林天然｜广西师范大学｜学者主页

2026

基于铜金属有机骨架纳米酶的活性检测与应用的智能手机辅助综合化学实验教学改革

林天然，侯丽

《广州化工》

DOI

2026

Ru-N coordination hydrogen-bonded organic frameworks with enhanced peroxidase-like activity for colorimetric determination of gastric cancer-related salivary D-amino acids

Haiting Liang, Qi Jiao, Jinghan Wu, Xiujuan Chen, Qi Liang, Li Hou, Shulin Zhao, Tianran Lin

Microchimica Acta

DOI

2026

Portable self-powered dual-photoelectrode PFC aptasensor based on the “on-off-on” signal response via a digital multimeter for dual-mycotoxin assay

Yanling Chen, Shanjuan Xu, Li Hou, Yanke Lu, Xiaojie Gao, Bo Weng, Tianran Lin, Shulin Zhao

Microchemical Journal

DOI

2025

Enzyme-free multicolor sensor for visual detection of malathion based on a bimetallic magnetic nanozyme-mediated gold nanorod etching

Yuanying Chen, Tianran Lin, Shuangshuang He, Jiao Qi, Shulin Zhao, Li Hou

Food Chemistry

DOI

2025

Colorimetric and ratio-fluorescence dual-mode assay for multicolor detection of acid phosphatase based on iron ions modified hydrogen-bonded organic framework nanozymes

Qi Jiao, Zihui Xie, Yuanying Chen, Shuangshuang He, Li Hou, Shulin Zhao, Tianran Lin

Analytica Chimica Acta

DOI

2025

Colorimetric and photothermal dual-mode vertical flow assay for sensitive detection of Escherichia coli O157:H7 based on 4-mercaptophenylboronic acid-functionalized Cu2-xSe-Au nanozyme

Tianran Lin, Xinlian Chen, Xiujuan Chen, Jincui Su, Hong Zhao, Shulin Zhao, Li Hou

Sensors and Actuators B Chemical

DOI

2025

Hydrogen-Bonded Organic Framework Nanozyme with Multi-Enzyme Activity for Chemiluminescence Sensing of Acetylcholinesterase and Screening Its Inhibitors

Yunping Lai, Shuangshuang He, Yuanying Chen, Tianran Lin, Li Hou, Shulin Zhao

Analytical Chemistry

DOI

2025

Pt nanoparticles functionalized hydrogen-bonded organic frameworks: A three-in-one nanozyme for colorimetric detection of alkaline phosphatase

Jiamin Huang, Hong Lin Zhao, Xinlian Chen, Tianran Lin, Li Hou, Shulin Zhao

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy

DOI

2025

Boric acid functionalized Cu2-xSe nanozyme for the immunomagnetic bead-based colorimetric assay of Escherichia coli O157:H7 coupled with smartphone

Xinlian Chen, Tianran Lin, Jincui Su, Li Hou, Shulin Zhao

Microchemical Journal

DOI

2025

Effect of reaction time on the morphology and electrochemical performance of Co₃O₄/Carbon cloth cathodes for zinc-ion batteries

Ke-Fan Wu, Zhe Wang, Yujia Wang, Ying Ma, Tianran Lin, You-Feng Zhang

International Journal of Electrochemical Science

DOI

2024

Rapid photothermal assay for ultrasensitive point-of-care detection of tumor markers based on a filter membrane

Shendong Liu, Xinlian Chen, Hong Zhao, Tianran Lin, Li Hou, Shulin Zhao

Microchimica Acta

DOI

2024

Dual-mode photothermal/chemiluminescence vertical flow assay for sensitive point-of-care detection of carcinoembryonic antigen using Cu2-xAgxS@liposome on a filter membrane

Yunping Lai, Jiamin Huang, Dianyong Tang, Xinlian Chen, Li Hou, Shulin Zhao, Tianran Lin

Biosensors and Bioelectronics

DOI

2024

An intelligent Cu/ZIF-8-based nanodrug delivery system for tumor-specific and synergistic therapy via tumor microenvironment-responsive cascade reaction

Fenghuang Wei, Li Hou, Yiyun Yao, Yunping Lai, Tianran Lin, Shulin Zhao, Dianping Tang

Microchimica Acta

DOI

2024

A novel split-type photoelectrochemical biosensor based on liposome-induced in situ formation of Bi2S3@BiOI/Ag2S heterojunction for the sensitive detection of CEA

Min Wang, Xiaojie Gao, Li Hou, Yanling Chen, Tianran Lin

Microchemical Journal

DOI

2023

基于双创型人才培养的化学类专业《仪器分析实验》课程教学改革

侯丽，林天然

《广州化工》

2023

肿瘤微环境智能响应型纳米载药系统用于多模态协同治疗

韦凤凰，侯丽，姚懿芸，来云平，林天然

《光谱学与光谱分析》

2023

杆菌肽与百里酚酞的共组装体用于大肠杆菌的可视化检测

陈新莲，林天然，蒋高艳，来云平，韦凤凰，侯丽

《光谱学与光谱分析》

2023

An intelligent readable and capture-antibody-independent lateral flow immunoassay based on Cu 2− x Se nanocrystals for point-of-care detection of Escherichia coli O157:H7

Yiyun Yao, Li Hou, Fenghuang Wei, Tianran Lin, Shulin Zhao

The Analyst

DOI

2023

An off–on fluorescence sensor based on hydrogen-bonded organic frameworks for the detection of glutathione

Xinlian Chen, Na Li, Tianran Lin, Jiamin Huang, Li Hou, Shulin Zhao

Microchemical Journal

DOI

2023

Iodide-Mediated Etching of Gold Nanostar for the Multicolor Visual Detection of Hydrogen Peroxide

Yunping Lai, Beirong Yu, Tianran Lin, Li Hou

Biosensors

DOI

2023

pH-Triggered visual detection of Escherichia coli based on the co-assembly of bacitracin and thymolphthalein

Tianran Lin, Yunping Lai, Gaoyan Jiang, Xinlian Chen, Li Hou, Shulin Zhao

Chemical Communications

DOI

2023

A methylene blue-functionalized DNA concatemer for the construction of a turn-off fluorescent immunosensor for the sensitive detection of carcinoembryonic antigen

Juanjuan Huang, Yanling Chen, Li Hou, Tianran Lin

Analytical Methods

DOI

2022

“三位一体”助力分析化学相关实验类课程的改革

林天然，侯丽，董家新，叶芳贵，田建袅，张亮亮，赵书林，邱建华，沈星灿

《大学化学》

2022

Design and preparation of a near-infrared-emissive nanosensor for the quantification and imaging of alpha-fetoprotein in vitro and in vivo

Yuefang Hu, Liangliang Zhang, Li Hou, Tianran Lin, Yulong Bai, Shulin Zhao

Sensors and Actuators B Chemical

DOI

2022

Gas-Mediated Immunoassay for the Carcinoembryonic Antigen at Atmospheric Pressure with Smartphone Coupling with the Fluorescence Quenching Length of Perovskite Capillary

Shendong Liu, Danxuan Lin, Yunping Lai, Li Hou, Tianran Lin, Shulin Zhao

Analytical Chemistry

DOI

2022

Zn-ZrMOF containing Lewis acid-base catalytic sites for hydrolysis and visual detection of profenofos

Li Hou, Xiaoyu Chen, Xuanhan Zhang, Yufang Tang, Yiyun Yao, Tianran Lin, Shulin Zhao

Sensors and Actuators B Chemical

DOI

2022

Polydopamine-Functionalized Copper Peroxide/ZIF-8 Nanoparticle-Based Fluorescence-Linked Immunosorbent Assay for the Sensitive Determination of Carcinoembryonic Antigen by Self-Supplied H2O2 Generation

Juanjuan Huang, Yiyun Yao, Yanling Chen, Tianran Lin, Li Hou, Dianping Tang

Biosensors

DOI

2022

Information encryption with a high information-carrying capacity based on a stimulus-responsive hydrogen-bonded organic framework and a smartphone

Tianran Lin, Chunsuo Tian, Ying Hui Sun, Shendong Liu, Di Wang, Li Hou, Shulin Zhao

Chinese Chemical Letters

DOI

2022

Homogeneous photoelectrochemical biosensor for sensitive detection of omethoate via ALP-mediated pesticide assay and Bi2S3@Bi2Sn2O7 heterojunction as photoactive material

Min Wang, Li Hou, Xiaoyu Chen, Tianran Lin

Analytical and Bioanalytical Chemistry

DOI

2022

Bacitracin-Functionalized Dextran-MoSe2 with Peroxidase-like and Near-Infrared Photothermal Activities for Low-Temperature and Synergetic Antibacterial Applications

Tianran Lin, Gaoyan Jiang, Danxuan Lin, Yunping Lai, Li Hou, Shulin Zhao

ACS Applied Bio Materials

DOI

2022

A silk-like hydrogen-bonded organic framework functionalized membrane with intrinsic catalytic activity for nonmetallic reduction of 4-nitrophenol

Tianran Lin, Ying Hui Sun, Chunsuo Tian, Di Wang, Li Hou, Fanggui Ye, Shulin Zhao

Chemical Engineering Journal

DOI

2022

Fluorescence immunosensor based on functional nanomaterials and its application in tumor biomarker detection

Juanjuan Huang, Fenghuang Wei, Yuling Cui, Li Hou, Tianran Lin

RSC Advances

DOI

2022

An ordered one-step colorimetric sensor for the selective determination of catechol based on the polyacrylic acid-coated cerium oxide with laccase-like activity

Xiaoyan Jiang, Min Wang, Li Hou, Tianran Lin

New Journal of Chemistry

DOI

2021

A FRET ratiometric fluorescence biosensor for the selective determination of pyrophosphate ion and pyrophosphatase activity based on difunctional Cu-MOF nanozyme

Li Hou, Yuanlin Huang, Tianran Lin, Fanggui Ye, Shulin Zhao

Biosensors and Bioelectronics X

DOI

2021

A ratiometric electrochemical biosensor via alkaline phosphatase mediated dissolution of nano-MnO2 and Ru(III) redox recycling for the determination of dimethoate

Li Hou, Xuanhan Zhang, Yuxiu Huang, Min Wang, Xiaoyu Chen, Tianran Lin, Yanhui Tan, Shulin Zhao

Journal of Pharmaceutical and Biomedical Analysis

DOI

2021

Multicolor and photothermal dual-mode assay of alkaline phosphatase based on the UV light-assisted etching of gold nanorods

Tianran Lin, Shendong Liu, Juanjuan Huang, Chunsuo Tian, Li Hou, Fanggui Ye, Shulin Zhao

Analytica Chimica Acta

DOI

2021

Carbon Dots with Absorption Red-Shifting for Two-Photon Fluorescence Imaging of Tumor Tissue pH and Synergistic Phototherapy

Yulong Bai, Jingjin Zhao, Shulong Wang, Tianran Lin, Fanggui Ye, Shulin Zhao

ACS Applied Materials & Interfaces

DOI

2021

Magneto-controlled fluorescent immunosensor for sensitive determination of biomarker via three-dimensional AuNCs/liposome networks

Li Hou, Juanjuan Huang, Shendong Liu, Tianran Lin, Shulin Zhao

Sensors and Actuators B Chemical

DOI

2021

A mitochondria-targeted ratiometric fluorescent nanoprobe for imaging of peroxynitrite in living cells

Keqin Yang, Li Hou, Zhifang Li, Tianran Lin, Jianniao Tian, Shulin Zhao

Talanta

DOI

2021

A self-correcting fluorescent assay of tyrosinase based on Fe-MIL-88B-NH2 nanozyme

Ying Sun, Tianran Lin, Cuihong Zeng, Gaoyan Jiang, Xuanhan Zhang, Fanggui Ye, Shulin Zhao

Microchimica Acta

DOI

2020

种基于智能手机可视化多色荧光检测碱性磷酸酶活性的方法——推荐一个本科生科研训练项目

秦雨欣，林天然，李金莹，覃思媛，侯丽

《大学化学》

2020

Michael reaction-assisted fluorescent sensor for selective and one step determination of catechol via bifunctional Fe-MIL-88NH2 nanozyme

Li Hou, Yuemei Qin, Tianran Lin, Ying Sun, Fanggui Ye, Shulin Zhao

Sensors and Actuators B Chemical

DOI

2020

A competitive immunoassay for electrochemical impedimetric determination of chlorpyrifos using a nanogold-modified glassy carbon electrode based on enzymatic biocatalytic precipitation

Li Hou, Xuanhan Zhang, Man Kong, Gaoyan Jiang, Ying Sun, Weiming Mo, Tianran Lin, Fanggui Ye, Shulin Zhao

Microchimica Acta

DOI

2020

Accelerating the peroxidase-like activity of MoSe 2 nanosheets at physiological pH by dextran modification

Gaoyan Jiang, Tianran Lin, Yuxin Qin, Xuanhan Zhang, Li Hou, Ying Sun, Juanjuan Huang, Shendong Liu, Shulin Zhao

Chemical Communications

DOI

2019

高校化学专业学生学习现状分析及对策研究

侯丽，林天然，梁东

《广东化工》

2019

Progress and Trend on the Regulation Methods for Nanozyme Activity and Its Application

Li Hou, Gaoyan Jiang, Ying Sun, Xuanhan Zhang, Juanjuan Huang, Shendong Liu, Tianran Lin, Fanggui Ye, Shulin Zhao

Catalysts

DOI

2019

A ratiometric multicolor fluorescence biosensor for visual detection of alkaline phosphatase activity via a smartphone

Li Hou, Yuxin Qin, Jinying Li, Siyuan Qin, Yuanlin Huang, Tianran Lin, Liangqia Guo, Fanggui Ye, Shulin Zhao

Biosensors and Bioelectronics

DOI

2019

Magnetic Cu/Fe3O4@FeOOH with intrinsic HRP-like activity at nearly neutral pH for one-step biosensing

Yuanlin Huang, Guangzhao Liang, Tianran Lin, Li Hou, Fanggui Ye, Shulin Zhao

Analytical and Bioanalytical Chemistry

DOI

2019

A bifunctional metal organic framework of type Fe(III)-BTC for cascade (enzymatic and enzyme-mimicking) colorimetric determination of glucose

Zhenghong Zhao, Junhong Pang, Wenren Liu, Tianran Lin, Fanggui Ye, Shulin Zhao

Microchimica Acta

DOI

2019

Colorimetric detection of blood glucose based on GOx@ZIF-8@Fe-polydopamine cascade reaction

Zhenghong Zhao, Tianran Lin, Wenren Liu, Li Hou, Fanggui Ye, Shulin Zhao

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy

DOI

2018

化学类专业仪器分析教学改革初探

侯丽，林天然，张宣晗，秦雨欣，李金莹，覃思源

《广东化工》

2018

Colorimetric detection of thioglycolic acid based on the enhanced Fe3+ ions Fenton reaction

Yuanlin Huang, Tianran Lin, Li Hou, Fanggui Ye, Shulin Zhao

Microchemical Journal

DOI

2018

Boron- and phenyl-codoped graphitic carbon nitride with greatly enhanced light responsive range for photocatalytic disinfection

Tianran Lin, Zhiping Song, Yarong Wu, Ling Chen, Shaoyun Wang, FengFu Fu, Liangqia Guo

Journal of Hazardous Materials

DOI

2018

Colorimetric detection of benzoyl peroxide based on the etching of silver nanoshells of Au@Ag nanorods

Tianran Lin, Minqing Zhang, Fuhai Xu, Xingyu Wang, Zhifei Xu, Liangqia Guo

Sensors and Actuators B Chemical

DOI

2018

A label-free fluorescence assay for hydrogen peroxide and glucose based on the bifunctional MIL-53(Fe) nanozyme

Tianran Lin, Yuemei Qin, Yuanlin Huang, Ruitao Yang, Li Hou, Fanggui Ye, Shulin Zhao

Chemical Communications

DOI

2017

化学类专业本科毕业论文(设计)教学改革初探

侯丽，莫蔚明，林天然

《广东化工》

2017

对分析化学理论和实验教学的几点思考

林天然，侯丽，叶芳贵

《广东化工》

精选作品

期刊论文

基于铜金属有机骨架纳米酶的活性检测与应用的智能手机辅助综合化学实验教学改革

Ru-N coordination hydrogen-bonded organic frameworks with enhanced peroxidase-like activity for colorimetric determination of gastric cancer-related salivary D-amino acids

Portable self-powered dual-photoelectrode PFC aptasensor based on the “on-off-on” signal response via a digital multimeter for dual-mycotoxin assay

Enzyme-free multicolor sensor for visual detection of malathion based on a bimetallic magnetic nanozyme-mediated gold nanorod etching

Colorimetric and ratio-fluorescence dual-mode assay for multicolor detection of acid phosphatase based on iron ions modified hydrogen-bonded organic framework nanozymes

Colorimetric and photothermal dual-mode vertical flow assay for sensitive detection of Escherichia coli O157:H7 based on 4-mercaptophenylboronic acid-functionalized Cu2-xSe-Au nanozyme

Hydrogen-Bonded Organic Framework Nanozyme with Multi-Enzyme Activity for Chemiluminescence Sensing of Acetylcholinesterase and Screening Its Inhibitors

Pt nanoparticles functionalized hydrogen-bonded organic frameworks: A three-in-one nanozyme for colorimetric detection of alkaline phosphatase

Boric acid functionalized Cu2-xSe nanozyme for the immunomagnetic bead-based colorimetric assay of Escherichia coli O157:H7 coupled with smartphone

Effect of reaction time on the morphology and electrochemical performance of Co₃O₄/Carbon cloth cathodes for zinc-ion batteries

Rapid photothermal assay for ultrasensitive point-of-care detection of tumor markers based on a filter membrane

Dual-mode photothermal/chemiluminescence vertical flow assay for sensitive point-of-care detection of carcinoembryonic antigen using Cu2-xAgxS@liposome on a filter membrane

An intelligent Cu/ZIF-8-based nanodrug delivery system for tumor-specific and synergistic therapy via tumor microenvironment-responsive cascade reaction

A novel split-type photoelectrochemical biosensor based on liposome-induced in situ formation of Bi2S3@BiOI/Ag2S heterojunction for the sensitive detection of CEA

基于双创型人才培养的化学类专业《仪器分析实验》课程教学改革

肿瘤微环境智能响应型纳米载药系统用于多模态协同治疗

杆菌肽与百里酚酞的共组装体用于大肠杆菌的可视化检测

An intelligent readable and capture-antibody-independent lateral flow immunoassay based on Cu 2− x Se nanocrystals for point-of-care detection of Escherichia coli O157:H7

An off–on fluorescence sensor based on hydrogen-bonded organic frameworks for the detection of glutathione

Iodide-Mediated Etching of Gold Nanostar for the Multicolor Visual Detection of Hydrogen Peroxide

pH-Triggered visual detection of Escherichia coli based on the co-assembly of bacitracin and thymolphthalein

A methylene blue-functionalized DNA concatemer for the construction of a turn-off fluorescent immunosensor for the sensitive detection of carcinoembryonic antigen

“三位一体”助力分析化学相关实验类课程的改革

Design and preparation of a near-infrared-emissive nanosensor for the quantification and imaging of alpha-fetoprotein in vitro and in vivo

Gas-Mediated Immunoassay for the Carcinoembryonic Antigen at Atmospheric Pressure with Smartphone Coupling with the Fluorescence Quenching Length of Perovskite Capillary

Zn-ZrMOF containing Lewis acid-base catalytic sites for hydrolysis and visual detection of profenofos

Polydopamine-Functionalized Copper Peroxide/ZIF-8 Nanoparticle-Based Fluorescence-Linked Immunosorbent Assay for the Sensitive Determination of Carcinoembryonic Antigen by Self-Supplied H2O2 Generation

Information encryption with a high information-carrying capacity based on a stimulus-responsive hydrogen-bonded organic framework and a smartphone

Homogeneous photoelectrochemical biosensor for sensitive detection of omethoate via ALP-mediated pesticide assay and Bi2S3@Bi2Sn2O7 heterojunction as photoactive material

Bacitracin-Functionalized Dextran-MoSe2 with Peroxidase-like and Near-Infrared Photothermal Activities for Low-Temperature and Synergetic Antibacterial Applications

A silk-like hydrogen-bonded organic framework functionalized membrane with intrinsic catalytic activity for nonmetallic reduction of 4-nitrophenol

Fluorescence immunosensor based on functional nanomaterials and its application in tumor biomarker detection

An ordered one-step colorimetric sensor for the selective determination of catechol based on the polyacrylic acid-coated cerium oxide with laccase-like activity

A FRET ratiometric fluorescence biosensor for the selective determination of pyrophosphate ion and pyrophosphatase activity based on difunctional Cu-MOF nanozyme

A ratiometric electrochemical biosensor via alkaline phosphatase mediated dissolution of nano-MnO2 and Ru(III) redox recycling for the determination of dimethoate

Multicolor and photothermal dual-mode assay of alkaline phosphatase based on the UV light-assisted etching of gold nanorods

Carbon Dots with Absorption Red-Shifting for Two-Photon Fluorescence Imaging of Tumor Tissue pH and Synergistic Phototherapy

Magneto-controlled fluorescent immunosensor for sensitive determination of biomarker via three-dimensional AuNCs/liposome networks

A mitochondria-targeted ratiometric fluorescent nanoprobe for imaging of peroxynitrite in living cells

A self-correcting fluorescent assay of tyrosinase based on Fe-MIL-88B-NH2 nanozyme

种基于智能手机可视化多色荧光检测碱性磷酸酶活性的方法——推荐一个本科生科研训练项目

Michael reaction-assisted fluorescent sensor for selective and one step determination of catechol via bifunctional Fe-MIL-88NH2 nanozyme

A competitive immunoassay for electrochemical impedimetric determination of chlorpyrifos using a nanogold-modified glassy carbon electrode based on enzymatic biocatalytic precipitation

Accelerating the peroxidase-like activity of MoSe 2 nanosheets at physiological pH by dextran modification

高校化学专业学生学习现状分析及对策研究

Progress and Trend on the Regulation Methods for Nanozyme Activity and Its Application

A ratiometric multicolor fluorescence biosensor for visual detection of alkaline phosphatase activity via a smartphone

Magnetic Cu/Fe3O4@FeOOH with intrinsic HRP-like activity at nearly neutral pH for one-step biosensing

A bifunctional metal organic framework of type Fe(III)-BTC for cascade (enzymatic and enzyme-mimicking) colorimetric determination of glucose

Colorimetric detection of blood glucose based on GOx@ZIF-8@Fe-polydopamine cascade reaction

化学类专业仪器分析教学改革初探

Colorimetric detection of thioglycolic acid based on the enhanced Fe3+ ions Fenton reaction

Boron- and phenyl-codoped graphitic carbon nitride with greatly enhanced light responsive range for photocatalytic disinfection

Colorimetric detection of benzoyl peroxide based on the etching of silver nanoshells of Au@Ag nanorods

A label-free fluorescence assay for hydrogen peroxide and glucose based on the bifunctional MIL-53(Fe) nanozyme

化学类专业本科毕业论文(设计)教学改革初探

对分析化学理论和实验教学的几点思考

会议论文

A MOF-based nanozyme fluorecent sensor for efficiently detecting tyrosinase activity

基于分级孔MOFs电化学传感平台的构建及其用于有机磷农药残留分析

基于GOx@ZIF-8@Fe-PDA的级联反应比色传感检测血糖

基于Fe(Ⅲ)类过氧化物酶活性的比色传感检测巯基乙酸

基于MIL-53(Fe)的荧光酶联免疫吸附测定方法的构建及其应用

基于荧光金属-有机框架UIO-66-NH 2 的亚硝酸盐测定

书籍章节

Fluorescence measurements, imaging and counting by a smartphone