周德方｜山东农业大学｜学者主页

百晓学者学者目录

精选作品

期刊论文

2025

基于RPA-CRISPR/Cas13a-LFD的鸭星状病毒2型快速可视化检测方法的建立

何书海，陶梦筱，王露遥，周德方，周静，成子强，黄立

《中国兽医学报》

DOI

2025

Avian leukosis virus subgroup J evades innate immunity by activating miR-155 to dually target TRAF3 and STAT1

Xinyue Zhang, Defang Zhou, Jing Zhou, Xiaoyang Liu, Longying Ding, Tianxing Yan, Mengyuan Shi, Shuhai He, Ziqiang Cheng

PLoS Pathogens

DOI

2025

Plus-strand RNA viruses hijack Musashi homolog 1 to shield viral RNA from cytoplasmic ribonuclease degradation

Defang Zhou, Menglu Xu, Qingjie Liu, Ruixue Xin, Gege Cui, Longying Ding, Xiaoyang Liu, Xinyue Zhang, Tianxing Yan, Jing Zhou, Shuhai He, Liangyu Yang, Bin Xiang, Ziqiang Cheng

Journal of Virology

DOI

2024

DCLK1 mediated cooperative acceleration of EMT by avian leukosis virus subgroup J and Marek’s disease virus via the Wnt/β-catenin pathway promotes tumor metastasis

Jing Zhou, Defang Zhou, Qian Zhang, Xinyue Zhang, Xiaoyang Liu, Longying Ding, Jing Wen, Xiaoyu Xu, Ziqiang Cheng

Journal of Virology

DOI

2023

miR-155 facilitates the synergistic replication between avian leukosis virus subgroup J and reticuloendotheliosis virus by targeting a dual pathway

Jingwen Xue, Defang Zhou, Jing Zhou, Xusheng Du, Xinyue Zhang, Xiaoyang Liu, Longying Ding, Ziqiang Cheng

Journal of Virology

DOI

2022

Musashi-1 and miR-147 Precursor Interaction Mediates Synergistic Oncogenicity Induced by Co-Infection of Two Avian Retroviruses

Defang Zhou, Longying Ding, Menglu Xu, Xiaoyao Liu, Jingwen Xue, Xinyue Zhang, Xusheng Du, Jing Zhou, Xiyao Cui, Ziqiang Cheng

Cells

DOI

2022

TMT-based proteomic analysis reveals integrins involved in the synergistic infection of reticuloendotheliosis virus and avian leukosis virus subgroup J

Xiyao Cui, Xinyue Zhang, Jingwen Xue, Yongxiu Yao, Defang Zhou, Ziqiang Cheng

BMC Veterinary Research

DOI

2022

Interaction of p10/p27 with macrophage migration inhibitory factor promotes avian leukosis virus subgroup J infection

Kunmei Yang, Jianhao Yang, Defang Zhou, Mingjun Zhu, Xusheng Du, Jing Zhou, Shenglong Liu, Ziqiang Cheng

Veterinary Microbiology

DOI

2021

High-frequency and activation of CD4+CD25+ T cells maintain persistent immunotolerance induced by congenital ALV-J infection

Shuhai He, Gaoying Zheng, Defang Zhou, Li Ping Huang, Jianguo Dong, Ziqiang Cheng

Veterinary Research

DOI

2021

The CCCH-Type Zinc Finger Antiviral Protein Relieves Immunosuppression of T Cells Induced by Avian Leukosis Virus Subgroup J via the NLP–PKC-δ–NFAT Pathway

Mingjun Zhu, Jing Zhou, Defang Zhou, Kunmei Yang, Bin Li, Ziqiang Cheng

Journal of Virology

DOI

2020

The Distribution and Localization of Collagen Triple Helix Repeat Containing-1 in Naturally and Experimentally Avian Leukosis Virus Subgroup J-Infected Chickens

Yu Pang, Defang Zhou, Jing Zhou, Jingwen Xue, Yiya Wang, Ziqiang Cheng

Frontiers in Veterinary Science

DOI

2020

Avian leukosis virus subgroup J induces B cell anergy mediated by Lyn inhibited BCR signal transduction

Shuhai He, Gaoying Zheng, Xiaoxia Yang, Jianguo Dong, Defang Zhou, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

Veterinary Microbiology

DOI

2019

Interplay between CTHRC1 and the SU protein of avian leukosis virus subgroup J (ALV-J) facilitates viral replication

Yu Pang, Defang Zhou, Jingwen Xue, Jing Zhou, Ya Zhang, Gaoying Zheng, Shiyu Yuan, Yongxiu Yao, Ziqiang Cheng

Virus Research

DOI

2019

Clonal anergy of CD117+chB6+ B cell progenitors induced by avian leukosis virus subgroup J is associated with immunological tolerance

Shuhai He, Gaoying Zheng, Defang Zhou, Gen Lin Li, Mingjun Zhu, Xusheng Du, Jing Zhou, Ziqiang Cheng

Retrovirology

DOI

2018

miRNA-155在ALV-J与REV共感染中对肌动蛋白细胞骨架通路的影响

李玲，庄萍萍，王小满，周德方，薛静雯，成子强，王桂花

《中国细胞生物学学报》

2018

J亚群禽白血病病毒与禽网状内皮组织增殖病病毒协同致瘤机制研究

周德方

《山东农业大学》

2018

Reticuloendotheliosis virus and avian leukosis virus subgroup J synergistically increase the accumulation of exosomal miRNAs

Defang Zhou, Jingwen Xue, Shuhai He, Xusheng Du, Jing Zhou, Chengui Li, Libo Huang, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

Retrovirology

DOI

2018

Outbreak of myelocytomatosis caused by mutational avian leukosis virus subgroup J in China, 2018

Defang Zhou, Jingwen Xue, Ya Zhang, Guihua Wang, Yongsheng Feng, Liping Hu, Yingli Shang, Ziqiang Cheng

Transboundary and Emerging Diseases

DOI

2018

A polyclonal antibody against extracellular loops 1 of chNHE1 blocks avian leukosis virus subgroup J infection

Wei Meng, Defang Zhou, Chengui Li, Guihua Wang, Libo Huang, Ziqiang Cheng

Research in Veterinary Science

DOI

2017

A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J

Xiaoyu Wang, Defang Zhou, Guihua Wang, Libo Huang, Qiankun Zheng, Chengui Li, Ziqiang Cheng

Vaccine

DOI

2017

Growth retardation induced by avian leukosis virus subgroup J associated with down-regulated Wnt/β-catenin pathway

Weiguo Feng, Defang Zhou, Wei Meng, Gen Lin Li, Pingping Zhuang, Zhifang Pan, Guihua Wang, Ziqiang Cheng

Microbial Pathogenesis

DOI

2016

Identification of a variant antigenic neutralizing epitope in hypervariable region 1 of avian leukosis virus subgroup J

Minbo Hou, Defang Zhou, Gen Li, Huijun Guo, Jianzhu Liu, Guihua Wang, Qiankun Zheng, Ziqiang Cheng

Vaccine

DOI

会议论文

2025

鸡贫血病毒诱导雏鸡再生障碍性贫血机制

严天行，王卓媛，李睿琪，陈守洁，周静，周德方，成子强

《中国畜牧兽医学会兽医病理学分会第二十八次学术研讨会、中国病理生理学会动物病理生理学专业委员会第二十七次学术研讨会、中国实验动物学会实验病理学专业委员会第七次学术研讨会、中国兽医协会兽医病理师分会第六次学术研讨会论文集》

DOI

2019

MDV和REV体外共感染状态下宿主细胞的蛋白组学分析

杜旭升，周静，周德方，成子强

《中国畜牧兽医学会兽医病理学分会第二十五次学术交流会、中国病理生理学会动物病理学专业委员会第二十四次学术研讨会、中国实验动物学会实验病理学专业委员会第四次学术研讨会、中国兽医病理学家第四次研讨会论文集》

2019

祖B细胞克隆无能与J亚群禽白血病病毒诱导的免疫耐受相关

何书海，郑高颖，周德方，李根，朱明君，成子强

2019

MiR-155介导ALV-J与REV协同复制机制初步研究

薛婧雯，周德方，郑高颖，袁世玉，张心悦，成子强

《中国畜牧兽医学会兽医病理学分会第二十五次学术交流会、中国病理生理学会动物病理学专业委员会第二十四次学术研讨会、中国实验动物学会实验病理学专业委员会第四次学术研讨会、中国兽医病理学家第四次研讨会》

2019

J亚群禽白血病病毒感染激活双肾上腺素样激酶-1促进DF-1细胞的增殖

周静，周德方，杜旭升，成子强

2019

广西玉林三家鸡场马立克氏病的发生与诊断

张贤文，周德方，成子强

2018

CD117 + chB6 + B细胞祖细分化障碍是ALV-J先天感染诱导免疫耐受的关键原因

何书海，郑高颖，周德方，李根，朱明君，周静，成子强

《中国畜牧兽医学会兽医病理学分会第二十四次学术研讨会、中国病理生理学会动物病理生理学专业委员会第二十三次学术研讨会、中国实验动物学会实验病理学专业委员会第三次学术研讨会、中国兽医病理学家第三次学术研讨会》

2018

J亚群禽白血病病毒及其囊膜表面蛋白gp85对禽网状内皮组织增殖病毒复制的影响

张贤文，周德方，成子强

2016

禽白血病病毒J亚群与鸡败血支原体混合感染的临床病理学观察

周德方，崔熙尧，成子强

《中国畜牧兽医学会2016年学术年会、中国畜牧兽医学会禽病学分会第十八次学术研讨会论文集》

DOI

2016

发现蛋鸡住白细胞原虫与禽腺病毒1型混合感染

周德方，李根，杜旭升，成子强

《中国畜牧兽医学会兽医病理学分会、中国病理生理学会动物病理生理专业委员会、中国实验动物学会实验病理学专业委员会2016年学术研讨会》

预印本

2020

Lyn inhibited BCR signal pathway mediates B-cell anergy induced by avian leukosis virus subgroup J

Shuhai He, Gaoying Zheng, Xiaoxia Yang, Jianguo Dong, Defang Zhou, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

DOI

2018

ALV-J and REV synergistically activate a new oncogene of KIAA1199 via NF-κB and EGFR signaling regulated by miR-147

Defang Zhou, Jingwen Xue, Pingping Zhuang, Xiyao Cui, Shuhai He, Shuai Su, Guihua Wang, Li Zhang, Chengui Li, Libo Huang, Yingli Shang, Yongxiu Yao, Venugopal Nair, Huang‐Ge Zhang, Ziqiang Cheng

bioRxiv (Cold Spring Harbor Laboratory)

DOI

研究方向

禽免疫抑制病理与防控禽病毒免疫逃逸及协同致瘤机制禽白血病病毒表位疫苗

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