姚后宗｜江西师范大学｜学者主页

2026

Design, synthesis, and anti-necroptotic activity of novel Phenylbenzothiazole receptor-interacting protein kinase 1 (RIPK1) inhibitors

Jing Tao, Yuelun Xu, Zijun Chen, Yang Liu, Xiong Zuo, Tao Yuan, Houzong Yao

Bioorganic & Medicinal Chemistry Letters

DOI

2025

Synthesis of nucleoside drugs for the treatment of HBV infection: An updated review

Houzong Yao, Xianjing Zheng, Minjie Liu, Yuanyuan Xu, Ping Xu, Fen‐Er Chen

Green Synthesis and Catalysis

DOI

2025

Organelle-targeted BODIPY-conjugated platinum( iv ) anticancer prodrugs for overcoming drug resistance

Yuanyuan Xu, Fengling Zhang, Miaomiao Li, Huimin Zhang, Yuhong Yuan, Siying Lin, Liuxuan Yao, Song Xu, Tao Yuan, Houzong Yao

Dalton Transactions

DOI

2025

Reactive Cysteines in Proteins are the Dominant Reductants for Platinum(IV) Prodrug Activation in Live Cells

Shu Chen, Wang Peng, Houzong Yao, Zhi-Qin Deng, Zhao Yue, Gong-Yuan Liu, Jiaqian Xu, Nai-Xin Lin, Weikang Xu, Jian-Bo Yue, Guangyu Zhu

Angewandte Chemie

DOI

2025

Harnessing platinum(IV) prodrugs as versatile photoinitiators and photocrosslinkers for multifunctional hydrogels and protein labeling

Jiaqian Xu, Qiyuan Zhou, Guohan Sun, Gong-Yuan Liu, Shu Chen, Zhao Yue, Ka-Yan Ng, Houzong Yao, Fu-Shing Li, Yung-Kang Peng, Guangyu Zhu

Nature Communications

DOI

2023

An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy

Gong-Yuan Liu, Ya-Chao Zhang, Houzong Yao, Zhi-Qin Deng, Shu Chen, Yue Wang, Wang Peng, Guo-Han Sun, Man-Kit Tse, Xian-Feng Chen, J. Yue, Yung-Kang Peng, Li-Dai Wang, G. Zhu

Science Advances

DOI

2022

Front Cover: Synthesis, Characterization, and Cytotoxicity of a Reactive Platinum(IV) Monotrifluoromethyl Complex (Eur. J. Inorg. Chem. 3/2023)

Yanpeng Liu, Houzong Yao, Man‐Kit Tse, Shu Chen, Shek‐Man Yiu, Guangyu Zhu

European Journal of Inorganic Chemistry

DOI

2022

Synthesis, Characterization, and Cytotoxicity of a Reactive Platinum(IV) Monotrifluoromethyl Complex

Yanpeng Liu, Houzong Yao, Man‐Kit Tse, Shu Chen, Shek‐Man Yiu, Guangyu Zhu

European Journal of Inorganic Chemistry

DOI

2022

Blood Components as Carriers for Small‐Molecule Platinum Anticancer Drugs

Houzong Yao, Guangyu Zhu

ChemMedChem

DOI

2022

Enhancing Circulation and Tumor Accumulation of Carboplatin via an Erythrocyte-Anchored Prodrug Strategy.

Houzong Yao, Zhigang Wang, Na Wang, Zhi-Qin Deng, Gong-Yuan Liu, Jiang Zhou, Shu Chen, Jia-Hai Shi, G. Zhu

Angewandte Chemie

DOI

2022

A platinum-based fluorescent "turn on" sensor to decipher the reduction of platinum(IV) prodrugs.

Houzong Yao, Guangyu Zhu

Dalton Transactions

DOI

2021

An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs

Zhi-Qin Deng, Cai Li, Shu Chen, Qiyuan Zhou, Zou-Feng Xu, Zhigang Wang, Houzong Yao, H. Hirao, G. Zhu

Chemical Science

DOI

2021

Optimization of axial ligands to promote the photoactivation of BODIPY-conjugated platinum(IV) anticancer prodrugs.

Houzong Yao, Yuliana F. Gunawan, Gong-Yuan Liu, Man-Kit Tse, G. Zhu

Dalton Transactions

DOI

2021

The influence of different carbonate ligands on the hydrolytic stability and reduction of platinum(IV) prodrugs.

Shu Chen, K. Ng, Qiyuan Zhou, Houzong Yao, Zhi-Qin Deng, Man-Kit Tse, G. Zhu

Dalton Transactions

DOI

2020

BODI-Pt, a Green-Light-Activatable and Carboplatin-Based Platinum(IV) Anticancer Prodrug with Enhanced Activation and Cytotoxicity.

Houzong Yao, Shu Chen, Zhi-Qin Deng, Man-Kit Tse, Yudai Matsuda, G. Zhu

Inorganic Chemistry

DOI

2020

Stability, Reduction, and Cytotoxicity of Platinum(IV) Anticancer Prodrugs Bearing Carbamate Axial Ligands: Comparison with Their Carboxylate Analogues.

Shu Chen, Houzong Yao, Qiyuan Zhou, Man-Kit Tse, Yuliana F. Gunawan, G. Zhu

Inorganic Chemistry

DOI

2019

Synthesis and Cytotoxic Study of a Platinum(IV) Anticancer Prodrug with Selectivity toward Luteinizing Hormone-Releasing Hormone (LHRH) Receptor-Positive Cancer Cells.

Houzong Yao, Zou-Feng Xu, Cai Li, Man-Kit Tse, Zixuan Tong, G. Zhu

Inorganic Chemistry

DOI

2016

Antischistosomal activity of N,N'-arylurea analogs against Schistosoma japonicum.

Houzong Yao, Feng-You Liu, Jinglei Chen, Yan Li, Jinhao Cui, Chun-Hua Qiao

Bioorganic & Medicinal Chemistry Letters

DOI

2015

Design, synthesis and biological evaluation of praziquantel and endoperoxide conjugates as antischistosomal agents.

Jing-jing Yang, J. Boissier, Jinglei Chen, Houzong Yao, Shilin Yang, A. Rognon, Chun-Hua Qiao

Future Medicinal Chemistry

DOI

2014

一种氟代丁酸腺苷衍生物的合成

姚后宗，尹伟，陈晶磊，乔春华

《有机化学》

2014

Rational Design and Synthesis of a Fluorinated Butyric Adenosine Derivative

Houzong Yao, W. Yin, Jinglei Chen, Chun-Hua Qiao

DOI

姚后宗

精选作品

期刊论文

Design, synthesis, and anti-necroptotic activity of novel Phenylbenzothiazole receptor-interacting protein kinase 1 (RIPK1) inhibitors

Synthesis of nucleoside drugs for the treatment of HBV infection: An updated review

Organelle-targeted BODIPY-conjugated platinum( iv ) anticancer prodrugs for overcoming drug resistance

Reactive Cysteines in Proteins are the Dominant Reductants for Platinum(IV) Prodrug Activation in Live Cells

Harnessing platinum(IV) prodrugs as versatile photoinitiators and photocrosslinkers for multifunctional hydrogels and protein labeling

An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy

Front Cover: Synthesis, Characterization, and Cytotoxicity of a Reactive Platinum(IV) Monotrifluoromethyl Complex (Eur. J. Inorg. Chem. 3/2023)

Synthesis, Characterization, and Cytotoxicity of a Reactive Platinum(IV) Monotrifluoromethyl Complex

Blood Components as Carriers for Small‐Molecule Platinum Anticancer Drugs

Enhancing Circulation and Tumor Accumulation of Carboplatin via an Erythrocyte-Anchored Prodrug Strategy.

A platinum-based fluorescent "turn on" sensor to decipher the reduction of platinum(IV) prodrugs.

An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs

Optimization of axial ligands to promote the photoactivation of BODIPY-conjugated platinum(IV) anticancer prodrugs.

The influence of different carbonate ligands on the hydrolytic stability and reduction of platinum(IV) prodrugs.

BODI-Pt, a Green-Light-Activatable and Carboplatin-Based Platinum(IV) Anticancer Prodrug with Enhanced Activation and Cytotoxicity.

Stability, Reduction, and Cytotoxicity of Platinum(IV) Anticancer Prodrugs Bearing Carbamate Axial Ligands: Comparison with Their Carboxylate Analogues.

Synthesis and Cytotoxic Study of a Platinum(IV) Anticancer Prodrug with Selectivity toward Luteinizing Hormone-Releasing Hormone (LHRH) Receptor-Positive Cancer Cells.

Antischistosomal activity of N,N'-arylurea analogs against Schistosoma japonicum.

Design, synthesis and biological evaluation of praziquantel and endoperoxide conjugates as antischistosomal agents.

一种氟代丁酸腺苷衍生物的合成

Rational Design and Synthesis of a Fluorinated Butyric Adenosine Derivative

研究方向