赵冰夏｜南方医科大学｜学者主页

2026

Gold nanozyme-decorated Cu/Mn MOFs simultaneously enhances immunogenicity and alleviates immunosuppression in triple-negative breast cancer

Haibo Lan, Zede Wu, J. Xia, Qiuyu Li, Mengdan Gao, Zhuo-Han Cai, Wei-Hong Tan, Min-Yi Liu, Zi-Ting Xu, Yang Gao, Li Zhang, Bingxia Zhao, Ying-Jia Li, Yu Liang

Journal of Nanobiotechnology

DOI

2026

Quantity‐Quality Dual‐Regulation Strategy: Enzyme‐Like Nanoclusters for Improved Cancer Immunotherapy

Min-Yi Liu, Min Liang, Tianyu Xiao, Mengdan Gao, Yushu Liao, Qiuyu Li, Haibo Lan, Shuting Zheng, Zede Wu, Jiaming Wu, Xiaoli Feng, Bingxia Zhao

Advanced Functional Materials

DOI

2025

Ion-interference amplifier nano-system enhances radiotherapy via mitochondrial dysfunction and efferocytosis Inhibition

Shuting Zheng, Yinfei Zheng, Honglei Hu, Min-Yi Liu, Chenxi He, Zede Wu, Meirong Hou, Guoqiang Liu, Yi-Kai Xu, Cheng-Gong Yan, Bingxia Zhao

Journal of Nanobiotechnology

DOI

2025

Copper metal-organic framework-based multifaceted strategy for boosting cancer therapy via synergistic cuproptosis and disulfidptosis.

Zede Wu, Mengdan Gao, Qiuyu Li, Haibo Lan, Yinfei Zheng, Shuting Zheng, Meirong Hou, Yi-Kai Xu, Zheyu Shen, Bingxia Zhao, Cheng-Gong Yan

Biomaterials

DOI

2025

Low-intensity pulsed ultrasound (LIPUS)-augmented calcicoptosis by calcium-based nanoparticles for enhanced immunogenic cell death induction in triple-negative breast cancer

Yang Gao, Zi-Ting Xu, Ying-Shan Gao, Li Zhang, Yu Liang, Qiuyu Li, Min-Yi Liu, Haibo Lan, Yanyan Zhang, Bingxia Zhao, Ying-Jia Li

Journal of Nanobiotechnology

DOI

2025

Multifunctional nanoagent for enhanced cancer radioimmunotherapy via pyroptosis and cGAS-STING activation

Zi-Ting Xu, Yang Gao, Li Zhang, Ying-Shan Gao, Yushu Liao, Yu Liang, Zhen Yuan, Ying-Jia Li, Bingxia Zhao, Ge Wen

Journal of Nanobiotechnology

DOI

2025

Exploiting metabolic vulnerabilities through synergistic ferroptosis and disulfidptosis for breast cancer therapy

Yu Liang, Haibo Lan, Qiuyu Li, Mengdan Gao, Min-Yi Liu, Zi-Ting Xu, Yang Gao, Li Zhang, Ying-Jia Li, Bingxia Zhao

Journal of Advanced Research

DOI

2025

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

Yinfei Zheng, Shuting Zheng, Yushu Liao, Zede Wu, Chenxi He, Qiuyu Li, Honglei Hu, Zheyu Shen, Yi-Kai Xu, Cheng-Gong Yan, Bingxia Zhao, Meirong Hou

Advancement of science

DOI

2025

Retraction Note: Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) Paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP)

Weihong Guo, Zhian Chen, Xiaoli Feng, Guodong Shen, Huilin Huang, Yanrui Liang, Bingxia Zhao, Guoxin Li, Yanfeng Hu

Journal of Nanobiotechnology

DOI

2024

Enhancing immunotherapy using a synergistic T-lymphocyte and neutrophil-targeting activation (TNTa) strategy for triple-negative breast cancer treatment

Li Zhang, Huajian Chen, Zhouyue Jiang, Zi-Ting Xu, Yang Gao, Ying-Shan Gao, Yu Liang, Qiuyu Li, Haibo Lan, Min-Yi Liu, Ying-Jia Li, Bingxia Zhao

Chemical Engineering Journal

DOI

2024

Radiotherapy-sensitized cancer immunotherapy via cGAS-STING immune pathway by activatable nanocascade reaction

Honglei Hu, Shuting Zheng, Chenxi He, Yinfei Zheng, Qiming Wei, Si-Wen Chen, Zede Wu, Yi-Kai Xu, Bingxia Zhao, Cheng-Gong Yan

Journal of Nanobiotechnology

DOI

2024

Reshaping Immunosuppressive Tumor Microenvironment Using Ferroptosis/Cuproptosis Nanosensitizers for Enhanced Radioimmunotherapy

Chenxi He, Nan Zhu, Ying Chen, Yinfei Zheng, Si-Wen Chen, Zede Wu, Shuting Zheng, Honglei Hu, Li Qi, Meirong Hou, Zheyu Shen, Bingxia Zhao, Weihong Guo, Cheng-Gong Yan

Advanced Functional Materials

DOI

2024

Enhancing Ferroptosis-Mediated Radiosensitization via Synergistic Disulfidptosis Induction.

Qiuyu Li, Zede Wu, Si-Wen Chen, Yu Liang, Kai Zhu, Ning Su, Tian-Cai Liu, Bingxia Zhao

ACS Nano

DOI

2024

Cancer Radiosensitization Nanoagent to Activate cGAS‐STING Pathway for Molecular Imaging Guided Synergistic Radio/Chemo/Immunotherapy

Zede Wu, Qiuyu Li, Kai Zhu, Shuting Zheng, Honglei Hu, Meirong Hou, Li Qi, Si-Wen Chen, Yi-Kai Xu, Bingxia Zhao, C. Yan

Advanced Healthcare Materials

DOI

2024

Less is More: Biomimetic Hybrid Membrane Nanocarriers for Highly Efficient Tumor Targeted Drug Delivery

Siwen Chen, Haibo Lan, Minyi Liu, Chenxi He, Qiuyu Li, Shuting Zheng, Yinfei Zheng, Zede Wu, Tiancai Liu, Bingxia Zhao

Small

DOI

2023

Proton Pump Inhibitor-Enhanced Nanocatalytic Ferroptosis Induction for Stimuli-responsive Dual-modal Molecular Imaging Guided Cancer Radiosensitization.

Shuting Zheng, Honglei Hu, Meirong Hou, Kai Zhu, Zede Wu, Li Qi, H. Xia, Guo-Qiang Liu, Yunyan Ren, Yi-Kai Xu, C. Yan, Bingxia Zhao

Acta Biomaterialia

DOI

2023

A Versatile NiS2/FeS2 hybrid nanocrystal for Synergistic Cancer Therapy by inducing Ferroptosis and Pyroptosis

Shuxiang Xu, Shuyi Zhou, Luoyijun Xie, Wenlong Dou, Rongjun Zhang, Bingxia Zhao, Xu Yang, Xue-Mei Fu, Miaomiao Yuan

Chemical Engineering Journal

DOI

2023

Cancer Immunotherapy Based on Cell Membrane-Coated Nanocomposites Augmenting cGAS/STING Activation by Efferocytosis Blockade.

Zhian Chen, Zhen-Hao Li, Hui-Lin Huang, Guodong Shen, Yingxin Ren, Xinyuan Mao, Ling-Zhi Wang, Zhen-Yuan Li, Weisheng Wang, Guoxin Li, Bingxia Zhao, Weihong Guo, Yan-Feng Hu

Small

DOI

2022

Cancer Cell Membrane Biomimetic Mesoporous Silica Nanotheranostics for Enhanced Ferroptosis-mediated Immuogenic Cell Death on Gastric Cancer

Weihong Guo, Zhian Chen, Zhen-Hao Li, Hui-Lin Huang, Yingxin Ren, Zhen-Yuan Li, Bingxia Zhao, Guo-Xin Li, Yan-Feng Hu

Chemical Engineering Journal

DOI

2022

Rapid synthesis of 'yolk-shell'-like nanosystem for MR molecular and chemo-radio sensitization.

Meirong Hou, Kai Zhu, Honglei Hu, Shuting Zheng, Zede Wu, Yunyan Ren, Bin Wu, Li Qi, Dong Wu, Yi-Kai Xu, C. Yan, Bingxia Zhao

Journal of Controlled Release

DOI

2022

Dual nanoenzymes loaded hollow mesoporous organotantalum nanospheres for chemo-radio sensitization.

Chao Peng, Y. Liang, Ning Su, Si-Wen Chen, Zhen Yuan, Yanqun Chen, Dong Wu, Bin Wu, Yang Zhang, Ziting Xu, Si Zheng, Ying-Jia Li, Bingxia Zhao

Journal of Controlled Release

DOI

2022

Tumor microenvironments self-activated cascade catalytic nanoscale metal organic frameworks as ferroptosis inducer for radiosensitization

Y. Liang, Chao Peng, Ning Su, Qiu-Tian Li, Si-Wen Chen, Dong Wu, Bin Wu, Yang Gao, Ziting Xu, Qing Dan, Si Zheng, Bingxia Zhao, Ying-Jia Li

Chemical Engineering Journal

DOI

2022

Immune microenvironment-reshaping Au@Bi_2Te_3 nanoparticles for spectral computed tomography/photoacoustic imaging-guided synergetic photo/radio/immunotherapy

Kai Zhu, Zede Wu, Qiu-Tian Li, Meirong Hou, Honglei Hu, Shuting Zheng, Li Qi, Yi-Kai Xu, C. Yan, Bingxia Zhao

Nano Reseach

DOI

2022

Functionalized Au@Cu-Sb-S Nanoparticles for Spectral CT/Photoacoustic Imaging-Guided Synergetic Photo-Radiotherapy in Breast Cancer

Honglei Hu, Shuting Zheng, Meirong Hou, K. Zhu, Chuyao Chen, Zede Wu, Li Qi, Yun-Zhu Ren, Bin Wu, Yi-Kai Xu, C. Yan, Bingxia Zhao

International Journal of Nanomedicine

DOI

2022

Improved Immunotherapy for Gastric Cancer by Nanocomposites with Capability of Triggering Dual-Damage of Nuclear/Mitochondrial DNA and Cgas/Sting-Mediated Innate Immunity

Weihong Guo, Zhian Chen, Zhenhao Li, Huilin Huang, Yingxin Ren, Bingxia Zhao, Guoxin Li, Yanfeng Hu

Chemical Engineering Journal

DOI

2021

Tumor microenvironments self-activated nanoscale metal-organic frameworks for ferroptosis based cancer chemodynamic/photothermal/chemo therapy

Yu Liang, Li Zhang, Chao Peng, Shi-Yu Zhang, Si-Wen Chen, Xin Qian, Wan-Xian Luo, Qing Dan, Yongyan Ren, Ying-Jia Li, Bingxia Zhao

Acta Pharmaceutica Sinica B

DOI

2021

Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP)

Weihong Guo, Zhian Chen, Xiao-Li Feng, G. Shen, Hui-Lin Huang, Yanrui Liang, Bingxia Zhao, Guo-Xin Li, Yan-Feng Hu

Journal of Nanobiotechnology

DOI

2021

Natural Melanin-Based Nanoparticles With Combined Chemo/Photothermal/Photodynamic Effect Induce Immunogenic Cell Death (ICD) on Tumor

Ding Liu, Hui-Lin Huang, Bingxia Zhao, Weihong Guo

Frontiers in Bioengineering and Biotechnology

DOI

2020

Biodegradable hollow mesoporous organosilica nanotheranostics (HMON) for multi-mode imaging and mild photo-therapeutic-induced mitochondrial damage on gastric cancer

Wei-Hong Guo, Zhian Chen, Jiajia Chen, Xiao-Li Feng, Yang Yang, Hui-Lin Huang, Yanrui Liang, G. Shen, Y. Liang, Chao Peng, Yanbing Li, Guo-Xin Li, Wen-Hua Huang, Bingxia Zhao, Yan-Feng Hu

Journal of Nanobiotechnology

DOI

2020

An acoustic/thermo-responsive hybrid system for advanced doxorubicin delivery in tumor treatment.

Li Zhang, Shi-Yu Zhang, Huajian Chen, Yu Liang, Bingxia Zhao, Wan-Xian Luo, Qian Xiao, Jin-Heng Li, Jun-Qiao Zhu, Chao Peng, Ya-ru Zhang, Zhe Hong, Ying Wang, Ying-Jia Li

Biomaterials Science

DOI

2020

CuS–NiS2 nanomaterials for MRI guided phototherapy of gastric carcinoma via triggering mitochondria-mediated apoptosis and MLKL/CAPG-mediated necroptosis

Jian Chen, Rongjun Zhang, Cheng Tao, Xiaofei Huang, Zide Chen, Xinping Li, Jian-Long Zhou, Q. Zeng, Bingxia Zhao, Miaomiao Yuan, Min Ma, Zheng-Zhi Wu

Nanotoxicology

DOI

2020

Bicompatible porous Co3O4 nanoplates with intrinsic tumor metastasis inhibition for multimodal imaging and DNA damage–mediated tumor synergetic photothermal/photodynamic therapy

Miaomiao Yuan, Shuxiang Xu, Qianbing Zhang, Bingxia Zhao, Bingbing Feng, Kai-yuan Ji, Lili Yu, Wancheng Chen, Meirong Hou, Yang Xu, Xue-Mei Fu

DOI

2020

Vitamin-B12-conjugated PLGA-PEG nanoparticles incorporating miR-532-3p induce mitochondrial damage by targeting apoptosis repressor with caspase recruitment domain (ARC) on CD320-overexpressed gastric cancer.

Zhian Chen, Yanrui Liang, Xiao-Li Feng, Y. Liang, Guo-Dong Shen, Hui-Lin Huang, Zhao-Yu Chen, Jiang Yu, Hao Liu, Tian Lin, Hao Chen, Dong Wu, Guo-Xin Li, Bingxia Zhao, Weihong Guo, Yan-Feng Hu

Materials Science and Engineering C: Materials for Biological Applications

DOI

2019

CuS-MnS2 nano-flowers for magnetic resonance imaging guided photothermal/photodynamic therapy of ovarian cancer through necroptosis.

Wancheng Chen, Xuefei Wang, Bingxia Zhao, Rongjun Zhang, Zhen Xie, Yi He, Ali Chen, Xiaofan Xie, K. Yao, M. Zhong, Miaomiao Yuan

Nanoscale

DOI

2019

Hollow Mesoporous Tantalum Oxide based Nanospheres for Triple Sensitization of Radiotherapy.

Chao Peng, Yu Liang, Yanqun Chen, Xin Qian, Wan-Xian Luo, Si-Wen Chen, Shi-Yu Zhang, Qing Dan, Li Zhang, Miaosheng Li, Miaomiao Yuan, Bingxia Zhao, Ying-Jia Li

ACS Applied Materials and Interfaces

DOI

2018

Multifunctional NIR-responsive poly(vinylpyrrolidone)-Cu-Sb-S nanotheranostic agent for photoacoustic imaging and photothermal/photodynamic therapy.

Meirong Hou, C. Yan, Ze-Long Chen, Qing-Liang Zhao, Miaomiao Yuan, Yi-Kai Xu, Bingxia Zhao

Acta Biomaterialia

DOI

赵冰夏

精选作品

期刊论文

Gold nanozyme-decorated Cu/Mn MOFs simultaneously enhances immunogenicity and alleviates immunosuppression in triple-negative breast cancer

Quantity‐Quality Dual‐Regulation Strategy: Enzyme‐Like Nanoclusters for Improved Cancer Immunotherapy

Ion-interference amplifier nano-system enhances radiotherapy via mitochondrial dysfunction and efferocytosis Inhibition

Copper metal-organic framework-based multifaceted strategy for boosting cancer therapy via synergistic cuproptosis and disulfidptosis.

Low-intensity pulsed ultrasound (LIPUS)-augmented calcicoptosis by calcium-based nanoparticles for enhanced immunogenic cell death induction in triple-negative breast cancer

Multifunctional nanoagent for enhanced cancer radioimmunotherapy via pyroptosis and cGAS-STING activation

Exploiting metabolic vulnerabilities through synergistic ferroptosis and disulfidptosis for breast cancer therapy

Nanosensitizer for Cancer Radioimmunotherapy via Anti‐IL‐35 Blockade Boosted Innate Immunity Activation

Retraction Note: Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) Paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP)

Enhancing immunotherapy using a synergistic T-lymphocyte and neutrophil-targeting activation (TNTa) strategy for triple-negative breast cancer treatment

Radiotherapy-sensitized cancer immunotherapy via cGAS-STING immune pathway by activatable nanocascade reaction

Reshaping Immunosuppressive Tumor Microenvironment Using Ferroptosis/Cuproptosis Nanosensitizers for Enhanced Radioimmunotherapy

Enhancing Ferroptosis-Mediated Radiosensitization via Synergistic Disulfidptosis Induction.

Cancer Radiosensitization Nanoagent to Activate cGAS‐STING Pathway for Molecular Imaging Guided Synergistic Radio/Chemo/Immunotherapy

Less is More: Biomimetic Hybrid Membrane Nanocarriers for Highly Efficient Tumor Targeted Drug Delivery

Proton Pump Inhibitor-Enhanced Nanocatalytic Ferroptosis Induction for Stimuli-responsive Dual-modal Molecular Imaging Guided Cancer Radiosensitization.

A Versatile NiS2/FeS2 hybrid nanocrystal for Synergistic Cancer Therapy by inducing Ferroptosis and Pyroptosis

Cancer Immunotherapy Based on Cell Membrane-Coated Nanocomposites Augmenting cGAS/STING Activation by Efferocytosis Blockade.

Cancer Cell Membrane Biomimetic Mesoporous Silica Nanotheranostics for Enhanced Ferroptosis-mediated Immuogenic Cell Death on Gastric Cancer

Rapid synthesis of 'yolk-shell'-like nanosystem for MR molecular and chemo-radio sensitization.

Dual nanoenzymes loaded hollow mesoporous organotantalum nanospheres for chemo-radio sensitization.

Tumor microenvironments self-activated cascade catalytic nanoscale metal organic frameworks as ferroptosis inducer for radiosensitization

Immune microenvironment-reshaping Au@Bi_2Te_3 nanoparticles for spectral computed tomography/photoacoustic imaging-guided synergetic photo/radio/immunotherapy

Functionalized Au@Cu-Sb-S Nanoparticles for Spectral CT/Photoacoustic Imaging-Guided Synergetic Photo-Radiotherapy in Breast Cancer

Improved Immunotherapy for Gastric Cancer by Nanocomposites with Capability of Triggering Dual-Damage of Nuclear/Mitochondrial DNA and Cgas/Sting-Mediated Innate Immunity

Tumor microenvironments self-activated nanoscale metal-organic frameworks for ferroptosis based cancer chemodynamic/photothermal/chemo therapy

Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP)

Natural Melanin-Based Nanoparticles With Combined Chemo/Photothermal/Photodynamic Effect Induce Immunogenic Cell Death (ICD) on Tumor

Biodegradable hollow mesoporous organosilica nanotheranostics (HMON) for multi-mode imaging and mild photo-therapeutic-induced mitochondrial damage on gastric cancer

An acoustic/thermo-responsive hybrid system for advanced doxorubicin delivery in tumor treatment.

CuS–NiS2 nanomaterials for MRI guided phototherapy of gastric carcinoma via triggering mitochondria-mediated apoptosis and MLKL/CAPG-mediated necroptosis

Bicompatible porous Co3O4 nanoplates with intrinsic tumor metastasis inhibition for multimodal imaging and DNA damage–mediated tumor synergetic photothermal/photodynamic therapy

Vitamin-B12-conjugated PLGA-PEG nanoparticles incorporating miR-532-3p induce mitochondrial damage by targeting apoptosis repressor with caspase recruitment domain (ARC) on CD320-overexpressed gastric cancer.

CuS-MnS2 nano-flowers for magnetic resonance imaging guided photothermal/photodynamic therapy of ovarian cancer through necroptosis.

Hollow Mesoporous Tantalum Oxide based Nanospheres for Triple Sensitization of Radiotherapy.

Multifunctional NIR-responsive poly(vinylpyrrolidone)-Cu-Sb-S nanotheranostic agent for photoacoustic imaging and photothermal/photodynamic therapy.

研究方向