百晓学者学者目录

孟志云

研究员,河南中医药大学

精选作品

期刊论文

2026

A Liposomal Delivery System of Blueberry Anthocyanins Ameliorates Corneal Laser Injury

Zihan Lv, Chao-Ran Li, Di Liang, Guangrui Chen, Meng-Qi Qiu, Zhiyun Meng, Ruo-Lan Gu, H. Gan, Zhuona Wu, Zai-Fu Yang, Gui-Fang Dou

Biomolecules

2025

具有止血活性的中药活性成分研究进展

吴鑫茹,胡瑄,孟志云,顾若兰,甘慧,吴卓娜,窦桂芳

《中华中医药杂志》

2025

三黄泻心汤联合还原型谷胱甘肽治疗脓毒症急性肾损伤临床观察

孟志云,刘瑞清

《中国中医药现代远程教育》

2024

病毒性肺炎中医病证结合动物模型研究进展

乔璇,翟慧婷,李南熹,杨磊,孟志云,刘曙晨,孙云波,甘慧,吴卓娜,窦桂芳,顾若兰

《中草药》

2024

Immune-Related Molecules CD3G and FERMT3: Novel Biomarkers Associated with Sepsis

Nanxi Li, Peng Ren, Jingya Wang, Xiao-Hui Zhu, Xuan Qiao, Zhirui Zeng, Tong Ye, Shanshan Wang, Zhiyun Meng, H. Gan, Shu-Chen Liu, Yun-Bo Sun, Xiaoxia Zhu, Gui-Fang Dou, Ruo-Lan Gu

International Journal of Molecular Sciences

2024

Preclinical Pharmacokinetics and Biodistribution of LR004, a Novel Antiepidermal Growth Factor Receptor Monoclonal Antibody

Ying Zheng, Gui-Fang Dou, Shu-Chen Liu, Zhiyun Meng, Eric I. Tsao, Gang Yu, Xiaoxia Zhu, Ruo-Lan Gu, Zhuona Wu, Yun-Bo Sun, Peng Han, H. Gan

Molecules

2024

A novel method to quantify chitosan in aqueous solutions by ultrahigh-performance liquid chromatography-tandem mass spectrometry.

Ting Xue, Lei Zhou, Fan-Jun Wang, Zhuang Tian, Nanxi Li, Tong Ye, Ruolin Hao, Lei Yang, Ruo-Lan Gu, H. Gan, Zhuona Wu, Xiaoxia Zhu, Shu-Chen Liu, Yun-Bo Sun, Gui-Fang Dou, Zhiyun Meng

Carbohydrate Polymers

2024

Development of bovine serum albumin-modified Fe3O4 embedded in porous α-ketoglutaric acid/chitosan (BSA/Fe3O4@KA/CS): A magnetically targeted hemostatic dressing for deep and irregular wounds.

Jin-Nan Guo, Yuanyuan Zhao, Guanqun Peng, Tong Ye, Xiao-Hui Zhu, Run-Tian Li, Jintao Shen, Lina Du, Shanshan Wang, Zhiyun Meng, H. Gan, Ruo-Lan Gu, Wenzhong Sun, Gui-Fang Dou, Shu-Chen Liu, Yun-Bo Sun

International Journal of Biological Macromolecules

2024

Injectable exosome-loaded quaternized chitosan/oxidized sodium alginate hydrogel with self-healing, bioadhesive, and antibacterial properties for treating combined radiation-wound injury

Guanqun Peng, Jia Hu, Jin-Nan Guo, Jiahui Dong, Yuanyuan Zhao, Tong Ye, Fengjun Xiao, Zhiyun Meng, H. Gan, Ruo-Lan Gu, Peng Han, Wenzhong Sun, Gui-Fang Dou, Yun-Bo Sun, Shu-Chen Liu

Chemical Engineering Journal

2024

Effect of different drying methods on the structure and properties of porous starch

Yuanyuan Zhao, S. Qiao, Xiao-Hui Zhu, Jin-Nan Guo, Guanqun Peng, Xiao-Xia Zhu, Ruo-Lan Gu, Zhiyun Meng, Zhuona Wu, H. Gan, Gui-Fang Dou, Yi-Guang Jin, Shu-Chen Liu, Yun-Bo Sun

Heliyon

2024

Highly Efficient Hemostatic Cross-Linked Polyacrylate Polymer Dressings for Immediate Hemostasis

Tong Ye, Zhiyuan Yang, Ruolin Hao, Jin-Nan Guo, Gui-Fang Dou, Zhiyun Meng, Shu-Chen Liu, Ruo-Lan Gu, Zhuona Wu, Yun-Bo Sun, Peng Han, Yi-Guang Jin, H. Gan

Polymers

2023

Effects of radon exposure on gut microbiota and its metabolites short-chain fatty acids in mice.

Huimeng Liu, Mei-Yu Wang, Guangrui Chen, Huiyu Zhou, Jiahui Dong, Lei Yang, Tong Li, Zhiyun Meng, Ruo-Lan Gu, H. Gan, Zhuona Wu, Shu-Chen Liu, Yun-Bo Sun, Yong Yuan, Gui-Fang Dou

Toxicology

2023

Blocking TRAIL-DR5 signaling pathway with soluble death receptor 5 fusion protein mitigates radiation-induced injury

Dan-Yang Zhao, Lei Yang, Peng Han, Haihui Zhang, Fan Wang, Zhiyun Meng, H. Gan, Zhuona Wu, Wenzhong Sun, Chuan Chen, Gui-Fang Dou, Ruo-Lan Gu

Frontiers in Pharmacology

2023

Effects of Radiation-Induced Skin Injury on Hyaluronan Degradation and Its Underlying Mechanisms

Jiahui Dong, Boyuan Ren, Yunfei Tian, Guanqun Peng, Huiting Zhai, Zhiyun Meng, Ruo-Lan Gu, H. Gan, Zhuona Wu, Yun-Bo Sun, Gui-Fang Dou, Shu-Chen Liu

Molecules

2023

Pharmacological Effects of Astragaloside IV: A Review

Yu-Tong Liang, Bi-Qiong Chen, Di Liang, Xiao-Xiao Quan, Ruo-Lan Gu, Zhiyun Meng, H. Gan, Zhuona Wu, Yun-Bo Sun, Shu-Chen Liu, Gui-Fang Dou

Molecules

2023

Combined Silver Sulfadiazine Nanosuspension with Thermosensitive Hydrogel: An Effective Antibacterial Treatment for Wound Healing in an Animal Model

Xiao-Ya Liu, Hai-ning Fan, Zhiyun Meng, Zhuona Wu, Ruo-Lan Gu, Xiaoxia Zhu, H. Gan, Gui-Fang Dou

International Journal of Nanomedicine

2023

A novel sodium polyacrylate–based stasis dressing to treat lethal hemorrhage in a penetrating trauma swine model

Wei Wang, Peng Han, Lei Yang, Zhiyun Meng, H. Gan, Zhuona Wu, Xiaoxia Zhu, Wenzhong Sun, Ruo-Lan Gu, Gui-Fang Dou

Journal of Trauma and Acute Care Surgery

2023

Glycosaminoglycans: Participants in Microvascular Coagulation of Sepsis

Nanxi Li, Ruolin Hao, Peng Ren, Jing-Ya Wang, Jiahui Dong, Tong Ye, Danyang Zhao, Xuan Qiao, Zhiyun Meng, H. Gan, Shu-Chen Liu, Yun-Bo Sun, Gui-Fang Dou, Ruo-Lan Gu

Thrombosis and Haemostasis

2023

Local Clays from China as Alternative Hemostatic Agents

Changjiao Gan, Hongjie Hu, Zhiyun Meng, Xiaoxia Zhu, Ruo-Lan Gu, Zhuona Wu, Wenzhong Sun, Peng Han, Hongliang Wang, Gui-Fang Dou, H. Gan

Molecules

2023

Effects of enzymatic treatments on different crystal types of starch

Yuanyuan Zhao, Yun-Bo Sun, Zhiyun Meng, Jingnan Guo, Guanqun Peng, Wenzhong Sun, Xiaoxia Zhu, Ruo-Lan Gu, Zhuona Wu, H. Gan, Gui-Fang Dou, Yi-Guang Jin, Shu-Chen Liu

Food Chemistry Advances

2023

Cepharanthine Ameliorates Pulmonary Fibrosis by Inhibiting the NF-κB/NLRP3 Pathway, Fibroblast-to-Myofibroblast Transition and Inflammation

Guangrui Chen, Jian Li, Huimeng Liu, Huiyu Zhou, Mingqi Liu, Di Liang, Zhiyun Meng, H. Gan, Zhuona Wu, Xiaoxia Zhu, Peng Han, Taoyun Liu, Ruo-Lan Gu, Shu-Chen Liu, Gui-Fang Dou

Molecules

2022

三黄泻心汤加味联合常规西药治疗脓毒症所致急性肾损伤42例

孟志云,刘瑞清,厉兆春,王斌

《河南中医》

2022

The pharmacokinetics and pharmacodynamics of a novel recombinant activated human factor VII, GEN-0828, in hemophilia B mice.

Yu-lu Liu, Xiao-Xia Zhu, Liyun Niu, Ya Gao, H. Gan, Zhuona Wu, Jian Li, Su-Xiang Feng, Gui-Fang Dou, Ruo-Lan Gu, Zhiyun Meng

Journal of Pharmacy and Science

2022

Evaluation of the metabolism of PEP06, an endostatin-RGDRGD 30-amino-acid polypeptide and a promising novel drug for targeting tumor cells

Liyun Niu, Huiyu Zhou, Y. Lian, Ya Gao, Yulu Liu, Ruo-Lan Gu, Zhuona Wu, Xiaoxia Zhu, H. Gan, Zhiyun Meng, Gui-Fang Dou

Journal of Pharmaceutical Analysis

2022

A rapid quantitative method by liquid chromatography–tandem mass spectrometry for the measurement of anthocyanins and their metabolic characteristics in Sprague–Dawley rats

Yueru Lian, Liyun Niu, Zhiyun Meng, Xiaoxia Zhu, Ruo-Lan Gu, Zhuona Wu, Jian Li, P. Han, Taoyun Liu, H. Gan, Gui-Fang Dou

European Food Research and Technology

2022

Preparation and characterization of tranexamic acid modified porous starch and its application as a hemostatic agent.

Xinhong Zhao, Yun-Bo Sun, Zhiyun Meng, Zhiyuan Yang, S. Fan, Tong Ye, Lei Yang, Tong Li, Ruo-Lan Gu, Zhuona Wu, H. Gan, Gui-Fang Dou, Yong-Xiu Qi, Shu-Chen Liu

International Journal of Biological Macromolecules

2022

Bioavailability Enhancement of Cepharanthine via Pulmonary Administration in Rats and Its Therapeutic Potential for Pulmonary Fibrosis Associated with COVID-19 Infection

Jian Li, Guangrui Chen, Zhiyun Meng, Zhuona Wu, H. Gan, Xiaoxia Zhu, P. Han, Taoyun Liu, Fan Wang, Ruo-Lan Gu, Gui-Fang Dou

Molecules

2022

Preparation of Chitosan/Clay Composites for Safe and Effective Hemorrhage Control

Zhiyuan Yang, Tong Ye, Fei Ma, Xinhong Zhao, Lei Yang, Gui-Fang Dou, H. Gan, Zhuona Wu, Xiaoxia Zhu, Ruo-Lan Gu, Zhiyun Meng

Molecules

2022

Accurate Determination of the Degree of Deacetylation of Chitosan Using UPLC–MS/MS

Ting Xue, Wen-Qing Wang, Zhiyuan Yang, Fan Wang, Lei Yang, Jian Li, H. Gan, Ruo-Lan Gu, Zhuona Wu, Gui-Fang Dou, Zhiyun Meng

International Journal of Molecular Sciences

2022

Evaluation of Novel Tranexamic Acid/Montmorillonite Intercalation Composite, as a New Type of Hemostatic Material

Fei Ma, Shujing Sui, Zhiyuan Yang, Tong Ye, Lei Yang, Peng Han, H. Gan, Zhuona Wu, Ruo-Lan Gu, Xiaoxia Zhu, Fei Li, Zhiyun Meng, Zhiping Jiang, Gui-Fang Dou

BioMed Research International

2022

Sdr5-Fc Alleviates Ir-Induced Keratinocyte Injury by Suppressing Trail-Mediated Apoptosis and the Trail-Induced Nf-Kb Activation Pathway

Huimin Li, Tong Li, Jiahui Dong, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Huimeng Liu, Gui-Fang Dou

Social Science Research Network

2021

An UPLC-MS/MS method to monitor Estriol injection and comparison of pharmacokinetic characteristics after irradiation

Han-min Zhang, Zhiyun Meng, Tong Ye, Taoyun Liu, Jian Li, Fei Ma, Ruo-Lan Gu, Xiaoxia Zhu, Zhuona Wu, Gui-Fang Dou, H. Gan

Radiation Medicine and Protection

2021

Lycium barbarum mitigates radiation injury via regulation of the immune function, gut microbiota, and related metabolites.

Ying Zheng, Xu Pang, Xiaoxia Zhu, Zhiyun Meng, Xiaojuan Chen, Jie Zhang, Qianzhi Ding, Qi Li, Gui-Fang Dou, Bai-Ping Ma

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2021

Hemostatic Efficacy and Biocompatibility Evaluation of a Novel Absorbable Porous Starch Hemostat

Jianjun Zhu, Zhuona Wu, Wenzhong Sun, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Xuan Guo, Gui-Fang Dou

Surgical Innovation

2021

In vitro and in vivo safety studies indicate that R15, a synthetic polyarginine peptide, could safely reverse the effects of unfractionated heparin

Tong Li, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Taoyun Liu, P. Han, Jia-Rui Gao, Su-Eun Han, Gui-Fang Dou

FEBS Open Bio

2020

Predicting the metabolic characteristics of neorudin, a novel anticoagulant fusion protein, in patients with deep vein thrombosis.

Xiao-Nan Dong, Zhiyun Meng, Ruo-Lan Gu, Xiaoxia Zhu, H. Gan, Jide Jin, Jiang-Lin Liu, Gui-Fang Dou

Thrombosis Research

2020

Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo

Y. Rong, Yi-Fan Tu, Tai-Jun Yin, Zhiyun Meng, Gui-Fang Dou, Ming Hu

Archives of Toxicology

2019

Characterization and Hemostatic Potential of Two Kaolins from Southern China

Changjiao Gan, Hong-Jie Hu, Zhiyun Meng, Xiaoxia Zhu, Ruo-Lan Gu, Zhuona Wu, Hongliang Wang, Dong-Gen Wang, H. Gan, Jinglin Wang, Gui-Fang Dou

Molecules

2019

Comparision of two new hemostatic dressings in controlling hemorrhage in a severe groin injury model in swine

Zhiyun Meng

The FASEB Journal

2019

Preclinical pharmacokinetics of M10 after intragastrical administration of M10-H and M10-Na in Wistar rats.

Jia-Rui Gao, Gui-Fang Dou, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Taoyun Liu, Su-Xiang Feng, Zhiyun Meng

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2019

Simultaneous quantitation of E0703, a novel radioprotective agent and its oxidative metabolite M1 in human plasma by UPLC-MS/MS, and application to clinical pharmacokinetics.

Jian Li, Zhiyun Meng, H. Gan, Ruo-Lan Gu, Zhuona Wu, Gui-Fang Dou, Yue Gao

Journal of Pharmaceutical and Biomedical Analysis

2019

Calcium ion-exchange cross-linked porous starch microparticles with improved hemostatic properties.

Jianjun Zhu, Yun-Bo Sun, Wenzhong Sun, Zhiyun Meng, Qiao-Li Shi, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Gui-Fang Dou

International Journal of Biological Macromolecules

2019

Development of a mass spectrometry method for the characterization of a series of chitosan.

Jing-Feng Li, Lifang Chen, Zhiyun Meng, Gui-Fang Dou

International Journal of Biological Macromolecules

2019

Pharmacokinetic Properties of Arsenic Species after Intravenous and Intragastrical Administration of Arsenic Trioxide Solution in Cynomolgus Macaques Using HPLC-ICP-MS

Qiao-Li Shi, Mingyan Ju, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Zhiyun Meng, Gui-Fang Dou

Molecules

2018

Application of ultra high‐performance liquid chromatography tandem mass spectrometry to investigate the regioselective glucuronidation of icaritin in vitro

Y. Rong, Zhiyun Meng, Jian Li, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Wenzhong Sun, Taoyun Liu, Ying Zheng, Mingji Jin, Jian Peng, Xinyu Wang, Gui-Fang Dou

Journal of Pharmaceutical and Biomedical Analysis

2018

Time-Course Investigation of Small Molecule Metabolites in MAP-Stored Red Blood Cells Using UPLC-QTOF-MS

Yong Zhou, Zhiyun Meng, H. Gan, Ying Zheng, Xiaoxia Zhu, Zhuona Wu, Jian Li, Ruo-Lan Gu, Gui-Fang Dou

Molecules

2018

Evaluating prodrug characteristics of a novel anticoagulant fusion protein neorudin, a prodrug targeting release of hirudin variant 2‐Lys47 at the thrombosis site, by means of in vitro pharmacokinetics

Xiaona Dong, Ruo-Lan Gu, Xiaoxia Zhu, H. Gan, Jiang-Lin Liu, Jide Jin, Zhiyun Meng, Gui-Fang Dou

European Journal of Pharmaceutical Sciences

2018

Silver sulfadiazine nanosuspension-loaded thermosensitive hydrogel as a topical antibacterial agent

Xiao-Ya Liu, H. Gan, Chao-Ran Hu, Wenzhong Sun, Xiaoxia Zhu, Zhiyun Meng, Ruo-Lan Gu, Zhuona Wu, Gui-Fang Dou

International Journal of Nanomedicine

2018

Preparation and characterization of a new type of porous starch microspheres (PSM) and effect of physicochemical properties on water uptake rate.

Jianjun Zhu, Wenzhong Sun, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Gui-Fang Dou

International Journal of Biological Macromolecules

2018

A LC-MS/MS method to monitor the concentration of HYD-PEP06, a RGD-modified Endostar mimetic peptide in rat blood.

Xiaona Dong, Yiwei Zhang, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Jian Li, Ying Zheng, Bao-Feng Yang, Gui-Fang Dou

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2018

An optimized LC-MS/MS method for determination of HYNIC-3PRGD2, a new promising imaging agent for tumor targeting, in rat plasma and its application.

Liyun Niu, Jian Li, Ruo-Lan Gu, Zhuona Wu, Xiaoxia Zhu, H. Gan, Bai-Ping Ma, Bing Jia, Fan Wang, Zhiyun Meng, Xinyu Wang, Gui-Fang Dou

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2017

Synthesis and pharmacokinetic property improvement of deuterated plinabulin 9

Jian-Chun Zhao, He-Juan Cheng, Tian-Wen Sun, Shi-Xiao Wang, Zhong-Peng Ding, Gui-Fang Dou, Zhiyun Meng, Hua-Shi Guan, Wen-Bao Li

Journal of Ocean University of China

2017

A sharp, robust, and quantitative method by liquid chromatography tandem mass spectrometry for the measurement of EAD for acute radiation syndrome and its application.

Yiwei Zhang, Jian Li, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Ying Zheng, Jin-Bin Wei, Gui-Fang Dou

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2017

Development, validation, and clinical pharmacokinetic application of ultra-performance liquid chromatography/tandem mass spectrometry method for simultaneously determining a novel recombinant hirudin derivative (Neorudin) and its active metabolite in human serum.

Xiaona Dong, Zhiyun Meng, Jide Jin, Ruo-Lan Gu, Gui-Fang Dou

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2016

Ability of Heparin to Reverse A Synthetic Peptide R15 Sulfate

Tong Li, Xiao-Xia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Zhiyun Meng, Gui-Fang Dou

2016

~(125)I-MIL50のラット体内での薬物動態学と生物分布【JST・京大機械翻訳】

Xiao Lei, Xiao-Xia Zhu, De-Cai Wang, Zhiyun Meng, H. Gan, Ruo-Lan Gu, Zhuona Wu, Ying Zheng, Jian Li, Ming Lu, Gui-Fang Dou

2016

硫酸R15のヘパリンへの拮抗作用【JST・京大機械翻訳】

Tong Li, Xiao-Xia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Zhiyun Meng, Gui-Fang Dou

2016

Evaluation of genipin-crosslinked chitosan hydrogels as a potential carrier for silver sulfadiazine nanocrystals.

Lei Gao, H. Gan, Zhiyun Meng, Ruo-Lan Gu, Zhuona Wu, Xiaoxia Zhu, Wenzhong Sun, Jian Li, Ying Zheng, T. Sun, Gui-Fang Dou

Colloids and Surfaces B: Biointerfaces

2016

Pharmacokinetics and pharmacodynamics of SCT800, a new recombinant FVIII, in hemophilia A mice

Ruo-Lan Gu, Liang Liu, Liangzhi Xie, Wenlin Gai, S. Cao, Zhiyun Meng, H. Gan, Zhuona Wu, Jian Li, Ying Zheng, Xiao-Xia Zhu, Gui-Fang Dou

Acta Pharmacologica Sinica

2016

Pharmacokinetics and bioavailability of tuftsin-derived T peptide, a promising antitumor agent, in beagles.

Ruo-Lan Gu, Yanlin He, Su-Eun Han, Shoujun Yuan, Yinghong An, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Zhuona Wu, Jian Li, Ying Zheng, Ling Zhang, Lei Gao, Gui-Fang Dou

Drug Metabolism and Pharmacokinetics

2016

A phase I trial of an oral subtype-selective histone deacetylase inhibitor, chidamide, in combination with paclitaxel and carboplatin in patients with advanced non-small cell lung cancer

Xing-Sheng Hu, Lin Wang, Lin Lin, Xiao-Hong Han, Gui-Fang Dou, Zhiyun Meng, Yuan-Kai Shi

Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

2016

進行肺非小細胞癌患者におけるパクリタキセルとカルボプラチンと併用した経口サブタイプ選択的ヒストンデアセチラーゼ阻害剤である、キダマイド,の第I相試験【Powered by NICT】

Xing-Sheng Hu, Lin Wang, Lin Lin, Xiao-Hong Han, Gui-Fang Dou, Zhiyun Meng, Yuan-Kai Shi

2016

Genipin cross-linked biogel as well as preparation method and application thereof

Gui-Fang Dou, Lei Gao, H. Gan, Zhiyun Meng, Tao Sun, Xiao-Xia Zhu, Ruo-Lan Gu, Zhuona Wu, Wenzhong Sun, Jian Li, Ying Zheng

2016

スルファジアジン銀ナノ結晶のための潜在的キャリアとしてのゲニピン‐架橋キトサンヒドロゲルの評価【Powered by NICT】

Lei Gao, H. Gan, Zhiyun Meng, Ruo-Lan Gu, Zhuona Wu, Xiaoxia Zhu, Wenzhong Sun, Jian Li, Ying Zheng, Tao Sun, Gui-Fang Dou

2015

New synthetic peptide with efficacy for heparin reversal and low toxicity and immunogenicity in comparison to protamine sulfate.

Tong Li, Zhiyun Meng, Xiaoxia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Jian Li, Ying Zheng, Taoyun Liu, P. Han, Su-Eun Han, Gui-Fang Dou

Biochemical and Biophysical Research Communications - BBRC

2015

Development and validation of a sensitive HPLC-MS/MS method for determination of chidamide (epidaza), a new benzamide class of selective histone deacetylase inhibitor, in human plasma and its clinical application.

Ruo-Lan Gu, Taoyun Liu, Xiaoxia Zhu, H. Gan, Zhuona Wu, Jian Li, Ying Zheng, Gui-Fang Dou, Zhiyun Meng

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2015

Quantitative and qualitative analysis of the novel antitumor 1,3,4-oxadiazole derivative (GLB) and its metabolites using HPLC-UV and UPLC-QTOF-MS

Pu Li, Xin Wang, Jian Li, Zhiyun Meng, Shu-Chun Li, Zhong-Jun Li, Ying-Ying Lu, Hong Ren, Ya-qing Lou, Chuang Lu, Gui-Fang Dou, Guo-Liang Zhang

Scientific Reports

2014

液相色谱-串联质谱法研究四物汤中芍药苷和芍药内酯苷在大鼠体内药代动力学

黄开福,王学美,孟志云,高月,李俭,甘慧,吴卓娜,朱晓霞,顾若兰,窦桂芳

《国际药学研究杂志》

2014

[Determination of yogliptin and its metabolite in Wistar rat plasma by liquid chromatography-tandem mass spectrometry].

Jun Dai, Zhiyun Meng, Xiao-Xia Zhu, H. Gan, Ruo-Lan Gu, Bo Yang, Li-Ying Yu, Gui-Fang Dou

Yao xue xue bao = Acta pharmaceutica Sinica

2014

A novel exendin-4 human serum albumin fusion protein, E2HSA, with an extended half-life and good glucoregulatory effect in healthy rhesus monkeys.

Ling Zhang, Lin Wang, Zhiyun Meng, H. Gan, Ruo-Lan Gu, Zhuona Wu, Lei Gao, Xiaoxia Zhu, Wenzhong Sun, Jian Li, Ying Zheng, Gui-Fang Dou

Biochemical and Biophysical Research Communications - BBRC

2014

Protamine analog peptides and pharmaceutically acceptable salts and Applications

Gui-Fang Dou, Su-Eun Han, Zhiyun Meng, Xiao-Xia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Taoyun Liu, Jian Li, Ying Zheng, Tong Li

2014

HPLC-MS/MS法同时测定大鼠血浆中优格列汀及其代谢产物

代俊婷,孟志云,朱晓霞,甘慧,顾若兰,杨波,余丽英,窦桂芳

《药学学报》

2014

Effects of genipin cross-linking of chitosan hydrogels on cellular adhesion and viability.

Lei Gao, H. Gan, Zhiyun Meng, Ruo-Lan Gu, Zhuona Wu, Ling Zhang, Xiaoxia Zhu, Wenzhong Sun, Jian Li, Ying Zheng, Gui-Fang Dou

Colloids and Surfaces B: Biointerfaces

2013

[In vitro metabolism of forscolin isolated from Coleus forskohlii].

Man Zhang, Zhiyun Meng, Xiao-Xia Zhu, Gui-Fang Dou

Yao xue xue bao = Acta pharmaceutica Sinica

2013

HPLC-MS/MS测定比格犬血浆中非诺贝酸浓度及其药代动力学研究

马飞,邢春宇,吴卓娜,孟志云,甘慧,朱晓霞,顾若兰,窦桂芳,王德才

《解放军药学学报》

2013

Protamine mimic peptide series with low molecular and application thereof

Gui-Fang Dou, Su-Eun Han, Zhiyun Meng, Xiao-Xia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Taoyun Liu, Jian Li

2013

Phase Ib study of chidamide (CS055), a new subtype-selective oral histone deacetylase inhibitor, in combination with paclitaxel and carboplatin in patients with advanced non-small cell lung cancer.

Xing-Sheng Hu, Yuan-Kai Shi, Lin Wang, Lin Lin, Xiao-Hong Han, Zhiyun Meng, Gui-Fang Dou, Yan Sun

2013

Self-locking quick hemostat

Gui-Fang Dou, Ruo-Lan Gu, Wei Chen, Zhiyun Meng, Hong-Bing Lu, Zhuona Wu, H. Gan, Xiao-Xia Zhu, Wenzhong Sun

2013

[Pharmacodynamics and pharmacokinetics of batroxobin in Beagle dog].

Zijia Zheng, Xiao-Xia Zhu, H. Gan, Ruo-Lan Gu, Zhuona Wu, Zhiyun Meng, Gui-Fang Dou

Yao xue xue bao = Acta pharmaceutica Sinica

2013

HPLC-MS/MS测定比格犬血浆中维他昔布浓度及其药代动力学研究

邢春宇,李靖,孟志云,吕鹏月,马飞,贺艳琳,冯育林,窦桂芳

《药物分析杂志》

2012

液相色谱-串联质谱法测定大鼠血浆中forsklin的浓度及其药代动力学(英文)

宋佃卫,王德才,孟志云,顾若兰,时美慧,吴卓娜,王敬泽,窦桂芳

《国际药学研究杂志》

2012

HPLC-MS/MS法测定大鼠血浆中LH14的含量

王彬,杨雷琼,吴卓娜,顾若兰,朱晓霞,孟志云,甘慧

《解放军药学学报》

2012

Enhanced oral bioavailability and anti‐tumour effect of paclitaxel by 20(s)‐ginsenoside Rg3 in vivo

Lei Yang, Bin Wang, H. Gan, Shou-Ting Fu, Xiao-Xia Zhu, Zhuona Wu, Da-wei Zhan, Ruo-Lan Gu, Gui-Fang Dou, Zhiyun Meng

Biopharmaceutics & drug disposition

2012

Phase I study of chidamide (CS055/HBI-8000), a new histone deacetylase inhibitor, in patients with advanced solid tumors and lymphomas

M. Dong, Z. Ning, P. Xing, Jia-lian Xu, H. Cao, Gui-Fang Dou, Zhiyun Meng, Yuan-Kai Shi, Xian-Ping Lu, F. Feng

Cancer Chemotherapy and Pharmacology

2011

[Lidamycin metabolism in vitro].

Yan Wen, Zhiyun Meng, Shu-Zhen Chen, Xiao-Xia Zhu, Gui-Fang Dou

Yao xue xue bao = Acta pharmaceutica Sinica

2011

Simultaneous determination of lidamycin enediyne chromophore (LDC) and its aromatized derivative (LDCA) using puerarin as internal standard in rat plasma by LC-MS/MS.

Y. Wen, Shu-Zhen Chen, Zhiyun Meng, H. Gan, Xiaoxia Zhu, Zhuona Wu, Ruo-Lan Gu, Gui-Fang Dou

Biomedical chromotography

2011

Determination of paclitaxel content in different parts of Taxus wallichiana var. mairei by HPLC internal standard method

Zhiyun Meng

2011

The Pharmalokinetics-pharmacodynamics study of an oral insulin hydrogel preparation

Zhiyun Meng

2011

1,5-二咖啡酰奎宁酸与其四乙酰化物相对生物利用度的研究

时美慧,顾若兰,甘慧,李俭,汤晴,宋佃卫,吴卓娜,董俊兴,孟志云

《解放军药学学报》

2010

An improved LC-MS/MS method for simultaneous determination of 1,5-dicaffeoylquinic acid and its active metabolites in human plasma and its application to a pharmacokinetic study in patients.

Jiang-Lin Liu, Gui-Fang Dou, Xiaona Dong, Dan Yuan, Xi-Wei Ji, Zhuona Wu, Zhiyun Meng

Biomedical chromotography

2010

液相色谱-电喷雾离子阱质谱法研究人尿中1,5-二咖啡酰奎宁酸的代谢产物

刘江林,袁丹,丁建刚,董晓娜,窦桂芳,吴卓娜,孟志云

《中国临床药理学杂志》

2010

The performance of a fly-larva shell-derived chitosan sponge as an absorbable surgical hemostatic agent.

Ruo-Lan Gu, Wenzhong Sun, Hong Zhou, Zhuona Wu, Zhiyun Meng, Xiao-Xiao Zhu, Qing-Zi Tang, Ji Dong, Gui-Fang Dou

Biomaterials

2010

Chitosan hemostatic sponge made from maggot shells as well as preparation method and application thereof

Zhuona Wu, Wenzhong Sun, Zhiyun Meng, Xiao-Xia Zhu, Yan-Lin Wang, H. Gan, Gui-Fang Dou, Ruo-Lan Gu

2010

Study on the metabolites of 1,5-dicaffeoylquinic acid in human urine by LC-ESI/MS/MS assay

Zhiyun Meng

2010

[LC-MSn analysis of metabolites of 1,2-[bis (1,2-benzisoselenazolone-3(2H)-ketone)]-ethane, a novel anti-cancer agent in rat].

Hai-yan Zhou, Zhiyun Meng, Gui-Fang Dou, Jin Ma, Ya-qing Lou, Guo-Liang Zhang

Yao xue xue bao = Acta pharmaceutica Sinica

2009

Quantitative determination of beta,beta-dimethylacrylshikonin (DASK) in rat whole blood by liquid chromatography-tandem mass spectrometry with pre-column derivation and its pharmacokinetic application.

Hui-Fang Tian, Dong-Xiao Sun, Gui-Fang Dou, Dan Yuan, Zhiyun Meng

Biomedical chromotography

2009

Simultaneous determination of epothilone D and its hydrolytic metabolite in human plasma by high performance liquid chromatography-tandem mass spectrometry for pharmacokinetic studies.

Chun-Lin Zhang, Lan Zhao, Wen-Yuan Qi, Zhiyun Meng, Guoxiang Sun, Gui-Fang Dou

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2009

[Rapid pharmacokinetics screening of drug candidates in vitro and in vivo].

Xiao-Hai Dong, Xiao-Xia Zhu, Zhiyun Meng, Jiang-Lin Liu, Ying-Lin Cao, Gui-Fang Dou

Yao xue xue bao = Acta pharmaceutica Sinica

2008

利肾血冲剂对慢性肾炎血瘀型患者血清中t-PA、PAI-1的影响及临床意义

刘春生,陈和平,韩淑莲,孟志云

《中医研究》

2008

R—hap在大鼠体内的组织分布,排泄及药动学研究

Jia-Yu Zhou, Zhiyun Meng, Gui-Fang Dou, Shou-Ting Fu, Zi-chun Hua, Xiang Yang, Jun Liu, Li-Jun Wei, Sun-Hua Zhang

2008

In vivo and in vitro metabolism of lefucoxib in rats.

Xuezhi Bi, Zhiyun Meng, He-Bing Chen, Xiaoxia Zhu, Gui-Fang Dou

Journal of Pharmaceutical and Biomedical Analysis

2008

Quantitative determination of acetylshikonin in macaque monkey blood by LC-ESI-MS/MS after precolumn derivatization with 2-mercaptoethanol and its application in pharmacokinetic study

Dong-Xiao Sun, Hui-Fang Tian, Zhiyun Meng, A. Du, Dan Yuan, Ruo-Lan Gu, Zhuona Wu, Gui-Fang Dou

Acta Pharmacologica Sinica

2008

[Recent advances in research on granulocyte colony-stimulating factor--review].

Jing-Min Yu, Zhiyun Meng, Gui-Fang Dou

Zhongguo shi yan xue ye xue za zhi

2008

小鼠灌胃3H-β,β-二甲基丙烯酰紫草素的组织分布与排泄研究

田慧芳,孙东晓,孟志云,袁丹,周佳雨,郑华宁,窦桂芳

《同位素》

2008

Development of a rapid and sensitive liquid chromatography/tandem mass spectrometry method for the determination of 1,2-[bis(1,2-benzisoselenazolone-3(2H)-ketone)]-ethane (BBSKE), a novel anti-cancer agent in rat plasma.

Hai-yan Zhou, Gui-Fang Dou, Zhiyun Meng, Ya-qing Lou, Guo-Liang Zhang

Biomedical chromotography

2008

[3H]-乙酰紫草素在小鼠体内的组织分布、排泄及血中分布研究

孙东晓,田慧芳,孟志云,周佳雨,丁建刚,吴广瑞,窦桂芳

《军事医学》

2007

[Biotherapy of cancer by anti-EGFR monoclonal antibody].

Jing Wang, Zhiyun Meng, S. Fu, Gui-Fang Dou

Zhongguo shi yan xue ye xue za zhi

2007

High performance liquid chromatographic determination of 1,2-[bis(1,2-benzisoselenazolone-3(2H)-ketone)]-ethane (BBSKE), a novel organoselenium compound, in dog plasma using pre-column derivatization and its application in pharmacokinetic study.

Hai-yan Zhou, Gui-Fang Dou, Zhiyun Meng, Ya-qing Lou, Guo-Liang Zhang

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2007

The Experimental Study of Shu Di,Cang Zhu and Different Compatibility of Them to Protect Rat's Remnant Kidney and Inhibit Transforming Growth Factor

Fa-Rong Zhang, Zhiyun Meng

2007

Simultaneous determination of 1,5-dicaffeoylquinic acid and its active metabolites in human plasma by liquid chromatography-tandem mass spectrometry for pharmacokinetic studies.

Ruo-Lan Gu, Gui-Fang Dou, Jing Wang, Jun-Xing Dong, Zhiyun Meng

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2007

Determination of lefucoxib in rat plasma, urine, and feces by high-performance liquid chromatography with fluorescence detection: application in pharmacokinetic studies.

Xuezhi Bi, Zhiyun Meng, Gui-Fang Dou

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2007

Pharmacokinetics and metabolism of 3,4-dichlorophenyl-propenoyl-sec.-butylamine in rats by high performance liquid chromatography-ion trap mass spectrometry.

Shu-Mei Wang, Gui-Fang Dou, Qiang Li, Ting Liu, Zhiyun Meng, Ya-qing Lou, Guo-Liang Zhang

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2006

熟地 苍术及两者不同配伍比例对大鼠残余肾功能的影响及其相使作用的研究

张法荣,苏珊珊,孟志云,朱继东

《中华中医药学刊》

2006

Pharmacokinetics and metabolism of 1,5-dicaffeoylquinic acid in rats following a single intravenous administration.

B. Yang, Zhiyun Meng, L.-P. Yan, J.-X. Dong, L.-B. Zou, Z.-M. Tang, Gui-Fang Dou

Journal of Pharmaceutical and Biomedical Analysis

2006

[Immunotherapy of non-Hodgkin's lymphomas (NHL) by anti-CD22 antibody--review].

Ping Lu, Zhiyun Meng, Mingzhu Zhou, Min-Wei Wang, Gui-Fang Dou

Zhongguo shi yan xue ye xue za zhi

2005

METABOLIC PROFILE OF 1,5-DICAFFEOYLQUINIC ACID IN RATS, AN IN VIVO AND IN VITRO STUDY

Bo Yang, Zhiyun Meng, Jun-Xing Dong, Liang-Ping Yan, Libo Zou, Zhong-Ming Tang, Gui-Fang Dou

Drug Metabolism And Disposition

2005

1,5-二咖啡酰奎宁酸对大鼠所微粒体细胞色素P450含量的影响

Bo Yang, Liang-Ping Yan, Zhiyun Meng, Li-Bo Zou, Gui-Fang Dou, Ya-Dong Zhang

2005

反相HPLC法测定大鼠血浆中17-烯丙胺基-17-脱甲基格尔德霉素及其代谢产物17-氨基-17-脱甲基格尔德霉素

佘高宏,孟志云,刘慧玲,王东援,窦桂芳

《药物分析杂志》

2005

RP-HPLC Measurement of 17-Allylamino-17-Demethoxygeldanamycin and Its Active Metabolite 7-Amino-17-Demethoxygeldanamycin in Rat Plasma

Gao-Hong She, Zhiyun Meng

2004

人抗凝血酶Ⅲ(AT-Ⅲ)在毕赤酵母中可溶性表达

于群,宋丽雅,贺敏,卜凤荣,孟志云,孙文种,章金刚

《中国生物制品学杂志》

2004

High performance liquid chromatography method for the determination of JBAT in human plasma sample

Y. Mu, Zhiyun Meng, Wen-Jing Gao, Gui-Fang Dou

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