李付琸｜复旦大学｜学者主页

2026

Selective C18-Methyl Oxidation of Sclareol via an Engineered P450 Enables the Synthesis of Spiromyrrhene B

Chenhao Zhang, Shugong Liu, Guanwen Chen, Ying Shi, Liran Chen, Daofeng Chen, Fuzhuo Li

Journal of the American Chemical Society

DOI

2025

Synthesis of diverse terpenoid frameworks via enzyme-enabled abiotic scaffold hop

Heping Deng, Junhong Yang, Fuzhuo Li, Jian Li, Hans Renata

Nature Chemistry

DOI

2024

基于P450选择性氧化的天然产物化学-酶法合成进展

程中玉，李付琸

《合成生物学》

2024

Chemoenzymatic synthesis of macrocyclic peptides and polyketides via thioesterase-catalyzed macrocyclization

Senze Qiao, Zhongyu Cheng, Fuzhuo Li

Beilstein Journal of Organic Chemistry

DOI

2024

Microbe Engineering to Provide Drimane‐Type Building Blocks for Chiral Pool Synthesis of Meroterpenoids

Wenyu Du, Zhongyu Cheng, Xingming Pan, Chenhao Liu, Mingyu Yue, Tianhao Li, Zhixi Xiao, Lu‐Lu Li, Xuelan Zeng, Xiaoxu Lin, Fuzhuo Li, Liao‐Bin Dong

Angewandte Chemie

DOI

2023

Author Correction: Chemoenzymatic approaches for exploring structure–activity relationship studies of bioactive natural products

Fuzhuo Li, Heping Deng, Hans Renata

Nature Synthesis

DOI

2023

Chemoenzymatic approaches for exploring structure–activity relationship studies of bioactive natural products

Fuzhuo Li, Heping Deng, Hans Renata

Nature Synthesis

DOI

2022

Remote B-Ring Oxidation of Sclareol with an Engineered P450 Facilitates Divergent Access to Complex Terpenoids.

Fuzhuo Li, Heping Deng, Hans Renata

Journal of the American Chemical Society

DOI

2021

Diastereoselective Synthesis of b-Branched a-Amino Acids via Bio-catalytic Dynamic Kinetic Resolution

Fuzhuo Li, Li-Cheng Yang, Jingyang Zhang, Jason S. Chen, Hans Renata

DOI

2021

A Unified Strategy to Access Trans-Syn-Fused Drimane Meroterpe-noids: Chemoenzymatic Total Syntheses of Polysin, N-Acetyl-Polyveoline and the Chrodrimanins

Fuzhuo Li, Hans Renata

DOI

2021

A Chiral-Pool-Based Strategy to Access trans-syn-Fused Drimane Meroterpenoids: Chemoenzymatic Total Syntheses of Polysin, N-Acetyl-polyveoline and the Chrodrimanins.

Fuzhuo Li, Hans Renata

Journal of the American Chemical Society

DOI

2021

Stereoselective Synthesis of β-Branched Aromatic α-Amino Acids via Biocatalytic Dynamic Kinetic Resolution

Fuzhuo Li, Li-Cheng Yang, Jingyang Zhang, Jason S. Chen, Hans Renata

Angewandte Chemie

DOI

2019

Merging Chemoenzymatic and Radical-Based Retrosynthetic Logic For Rapid and Modular Synthesis of Oxidised Meroterpenoids

Jian Li, Fuzhuo Li, E. King-Smith, Hans Renata

Nature Chemistry

DOI

2018

Enzymatic C–H Functionalizations for Natural Product Synthesis

Fuzhuo Li, Xiao Zhang, Hans Renata

Current Opinion in Chemical Biology

DOI

2017

Bioinspired Asymmetric Synthesis of Hispidanin A.

Fuzhuo Li, Q. Tu, Si-Jia Chen, Lei Zhu, Y. Lan, Jianxian Gong, Zhen Yang

Angewandte Chemie

DOI

2016

A chiral pool approach for asymmetric syntheses of (-)-antrocin, (+)-asperolide C, and (-)-trans-ozic acid.

Fuzhuo Li, Shuang Li, Pengpeng Zhang, Zhihui Huang, Wei-Bin Zhang, Jianxian Gong, Zhen Yang

Chemical Communications

DOI

2015

Asymmetric Total Synthesis of (-)-Maoecrystal V.

Wei-Bin Zhang, Wen-Bing Shao, Fuzhuo Li, Jian-Xian Gong, Zhen Yang

Chemistry - An Asian Journal

DOI

2015

Palladium-catalyzed carbonylative cyclization of aryl alkenes/alkenols: a new reaction mode for the synthesis of electron-rich chromanes.

Shuang Li, Fuzhuo Li, Jianxian Gong, Zhen Yang

Organic Letters

DOI

2014

Collective synthesis of humulanolides using a metathesis cascade reaction.

Jing-Chun Han, Fuzhuo Li, Chuang-Chuang Li

Journal of the American Chemical Society

DOI

李付琸

精选作品

期刊论文

Selective C18-Methyl Oxidation of Sclareol via an Engineered P450 Enables the Synthesis of Spiromyrrhene B

Synthesis of diverse terpenoid frameworks via enzyme-enabled abiotic scaffold hop

基于P450选择性氧化的天然产物化学-酶法合成进展

Chemoenzymatic synthesis of macrocyclic peptides and polyketides via thioesterase-catalyzed macrocyclization

Microbe Engineering to Provide Drimane‐Type Building Blocks for Chiral Pool Synthesis of Meroterpenoids

Author Correction: Chemoenzymatic approaches for exploring structure–activity relationship studies of bioactive natural products

Chemoenzymatic approaches for exploring structure–activity relationship studies of bioactive natural products

Remote B-Ring Oxidation of Sclareol with an Engineered P450 Facilitates Divergent Access to Complex Terpenoids.

Diastereoselective Synthesis of b-Branched a-Amino Acids via Bio-catalytic Dynamic Kinetic Resolution

A Unified Strategy to Access Trans-Syn-Fused Drimane Meroterpe-noids: Chemoenzymatic Total Syntheses of Polysin, N-Acetyl-Polyveoline and the Chrodrimanins

A Chiral-Pool-Based Strategy to Access trans-syn-Fused Drimane Meroterpenoids: Chemoenzymatic Total Syntheses of Polysin, N-Acetyl-polyveoline and the Chrodrimanins.

Stereoselective Synthesis of β-Branched Aromatic α-Amino Acids via Biocatalytic Dynamic Kinetic Resolution

Merging Chemoenzymatic and Radical-Based Retrosynthetic Logic For Rapid and Modular Synthesis of Oxidised Meroterpenoids

Enzymatic C–H Functionalizations for Natural Product Synthesis

Bioinspired Asymmetric Synthesis of Hispidanin A.

A chiral pool approach for asymmetric syntheses of (-)-antrocin, (+)-asperolide C, and (-)-trans-ozic acid.

Asymmetric Total Synthesis of (-)-Maoecrystal V.

Palladium-catalyzed carbonylative cyclization of aryl alkenes/alkenols: a new reaction mode for the synthesis of electron-rich chromanes.

Collective synthesis of humulanolides using a metathesis cascade reaction.

研究方向