张世卿｜暨南大学｜学者主页

2026

Discovery and Bioinspired Synthesis of Neuroprotective Geranylated Chalcones From Artocarpus communis

Rui-Li Huang, Shiqing Zhang, Bi‐Hai Chen, Yan Pan, Qiuping Miao, Xiao‐Jun Huang, Jian‐Guo Song, Wen Li, Lei Shi, Wen‐Cai Ye, Lijun Hu, Ying Wang

Angewandte Chemie

DOI

2026

Betulinaldehyde Ameliorates Aβ‐Induced Neurotoxicity and Cognitive Deficits by Modulating the eEF2K / eEF2 Pathway

Wang Cs, Xiaohe Han, Yali Lin, Yan Pan, Qiuping Miao, Yaping Wang, Shaobo Wang, Zhu Zhang, Luyao Wang, Zhi‐Ri Tang, Yinghui Peng, Ken Kin Lam Yung, Nan Ma, Dan Lu, Shiqing Zhang, Lei Shi

CNS Neuroscience & Therapeutics

DOI

2025

Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions

Daji Guo, Mengjiao Cai, Yanmin Xian, Yinyin Chen, Yujun Feng, Chun Hu, Lizhang Zeng, Lei Shi, Shiqing Zhang

CNS Neuroscience & Therapeutics

DOI

2025

In-Silico Screening-Based Discovery of New Natural eEF2K Inhibitors with Neuritogenic Activity

Shaobo Wang, Xinyu Wang, Lingling Guo, Xiaoxia Chen, Xiao‐Jun Huang, Shiqing Zhang, Wen‐Cai Ye, Xiaoqi Zhang, Lei Shi, Ying Wang, Lijun Hu

ACS Medicinal Chemistry Letters

DOI

2025

Deep Hypothermic Low Flow Results in Multiple Aspects of Neurological Deficits in Mice by eEF2 Hyperphosphorylation

Yumei Liao, Dongyang Che, Peng Liu, Xinyu Wang, Yanlin Zhang, Lingling Guo, Jinlin Hu, Tianyao Li, Lam Mei Fong, Nan Ma, Shiqing Zhang, Hua Lu, Lei Shi, Xiaoshen Zhang

Molecular Neurobiology

DOI

2025

Bioinformatic Identification of Risk Factors from an Immunological Viewpoint in Idiopathic Parkinson’s Disease

Zhenshan Sun, Pengfei Fu, Shiqing Zhang, Ken K. L. Yung

Journal of Neurorestoratology

DOI

2025

The gut microbiota in post-stroke depression: A systematic review of microbial mechanisms and therapeutic targeting of neuroinflammation.

Qianwen Zhang, Shiqing Zhang, Xingqin Cao, Ying-Hao Zhi, Ying Guo

Microbiology Research

DOI

2025

Exploring the mechanism of Polygonum Cuspidatum in the treatment of ischemic stroke by network pharmacology analysis and experimental validation.

Xingqin Cao, Shiqing Zhang, Mingjiang Mao, Qianwen Zhang, Ying Guo

Fitoterapia

DOI

2024

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu

Advanced Science

DOI

2023

The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation

Yumei Liao, Jun-Ya Wang, Pan Yan, Xueyi Zou, Chaoqun Wang, Yinghui Peng, Yun‐Lin Ao, Lam Mei Fong, Xiaoshen Zhang, Xiaoshen Zhang, Xiao‐Qi Zhang, Xiao‐Qi Zhang, Lei Shi, Shiqing Zhang

Molecules

DOI

2022

去甲氧基姜黄素通过促进海马神经发生对阿尔兹海默症认知损伤的改善作用

林凯莉，张世卿

《中成药》

2022

Tenuigenin ameliorates cognitive dysfunction in Alzheimer’s disease via hippocampal neurogenesis enhancement

Kai-Li Lin, Zhu Zhang, Zhang Zhang, Wen-jun Ding, Pei-Ru Zhu, Ying Wang, Xiao-Li Jiang, Bin Liu, Ken K. L. Yung, Shiqing Zhang

Phytochemistry Letters

DOI

2022

Facet-Dependent Activity of CeO2 Nanozymes Regulate the Fate of Human Neural Progenitor Cell via Redox Homeostasis.

Ying Wang, Zi-Cong Tan, Zhu Zhang, Pei-Ru Zhu, Sze-Wah Tam, Zhang Zhang, Xiao-Li Jiang, Kai-Li Lin, Linyuan Tian, Zhi-Feng Huang, Shiqing Zhang, Yung-Kang Peng, Ken K. L. Yung

ACS Applied Materials and Interfaces

DOI

2021

ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome

Xiaoyan Wu, Jin-yan Lv, Shiqing Zhang, X. Yi, Ziwei Xu, Yuanxing Zhi, Bo-Xin Zhao, Jian-Xin Pang, Ken K. L. Yung, Shu-Wen Liu, Pingzheng Zhou

Acta Pharmacologica Sinica

DOI

2021

Protective Effect of An-Gong-Niu-Huang Wan Pre-treatment Against Experimental Cerebral Ischemia Injury via Regulating GSK-3β/HO-1 Pathway

Shiqing Zhang, Xiao-Li Jiang, Ying Wang, Kai-Li Lin, Zhang Zhang, Zhu Zhang, Pei-Li Zhu, Man-Ling Ng, Shao-Gang Qu, S. Sze, Ken K. L. Yung

Frontiers in Pharmacology

DOI

2021

Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway

Kai-Li Lin, Zhang Zhang, Zhu Zhang, Pei-Li Zhu, Xiao-Li Jiang, Ying Wang, Qiu-Di Deng, Ken K. L. Yung, Shiqing Zhang

Pharmaceuticals

DOI

2021

Effects of α-Synuclein-Associated Post-Translational Modifications in Parkinson's Disease.

Song-Zhe He, Fu-Shun Wang, Ken K. L. Yung, Shiqing Zhang, Shao-Gang Qu

ACS Chemical Neuroscience

DOI

2020

Interaction of Sp1 and APP promoter elucidates a mechanism for Pb2+ caused neurodegeneration.

Qi Gao, Zi-Wen Dai, Shiqing Zhang, Yuqiang Fang, Ken K. L. Yung, P. Lo, K. Lai

Archives of Biochemistry and Biophysics

DOI

2020

20(S)-protopanaxadiol and oleanolic acid ameliorate cognitive deficits in APP/PS1 transgenic mice by enhancing hippocampal neurogenesis

Kai-Li Lin, S. Sze, Bin Liu, Zhang Zhang, Zhu Zhang, Pei-Ru Zhu, Ying Wang, Qiu-Di Deng, Ken K. L. Yung, Shiqing Zhang

Journal of Ginseng Research

DOI

2019

20(S)-protopanaxadiol promotes the migration, proliferation, and differentiation of neural stem cells by targeting GSK-3β in the Wnt/GSK-3β/β-catenin pathway

Kai-Li Lin, Bin Liu, Sze-Lam Lim, Xiuqiong Fu, S. Sze, Keng-Ang Yung, Shiqing Zhang

Journal of Ginseng Research

DOI

2019

Traditional Chinese medicine-based neurorestorative therapy for Alzheimer’s and Parkinson’s disease

Zhu Zhang, Shiqing Zhang, C. N. Lui, Pei-Li Zhu, Zhang Zhang, Kai-Li Lin, Yiwu Dai, Ken K. L. Yung

Journal of Neurorestoratology

DOI

2019

Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)

Shiqing Zhang, Peng Sun, Kai-Li Lin, Florence Hiu Ling Chan, Qi Gao, Wai-Fung Lau, V. A. L. Roy, Hongqi Zhang, K. Lai, Zhi-Feng Huang, Ken K. L. Yung

Advancement of science

DOI

2019

Roles of Glutamate Receptors in Parkinson’s Disease

Zhu Zhang, Shiqing Zhang, Pengfei Fu, Zhang Zhang, Kai-Li Lin, J. Ko, Ken K. L. Yung

International Journal of Molecular Sciences

DOI

2019

DCPIB, an Inhibitor of Volume-Regulated Anion Channels, Distinctly Modulates K2P Channels.

Jin-yan Lv, Ye-mei Liang, Shiqing Zhang, Qun-Sheng Lan, Ziwei Xu, Xiaoyan Wu, L. Kang, Jing Ren, Ying Cao, Ting Wu, Kai-Li Lin, Ken K. L. Yung, Xiong Cao, Jianxin Pang, Pingzheng Zhou

ACS Chemical Neuroscience

DOI

2019

Dynamic effect of beta-amyloid 42 on cell mechanics.

Qi Gao, Yuqiang Fang, Shiqing Zhang, H. Wong, Y. Chan, Samantha Sze Man Wong, Ken K. L. Yung, K. Lai

Journal of Biomechanics

DOI

2019

Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats

Shiqing Zhang, Peng Sun, Kai-Li Lin, Florence Hiu Ling Chan, Qi Gao, Wai-Fung Lau, V. A. L. Roy, Hongqi Zhang, K. Lai, Zhi-Feng Huang, Ken K. L. Yung

Advancement of science

DOI

2018

Biophysical Characteristics of Human Neuroblastoma Cell in Oligomeric $\beta $ -Amyloid (1–40) Cytotoxicity

Qi Gao, Yuqiang Fang, Shiqing Zhang, Hung-Wing Li, Ken K. L. Yung, K. Lai

IEEE Transactions on Nanobioscience

DOI

张世卿

精选作品

期刊论文

Discovery and Bioinspired Synthesis of Neuroprotective Geranylated Chalcones From Artocarpus communis

Betulinaldehyde Ameliorates Aβ‐Induced Neurotoxicity and Cognitive Deficits by Modulating the eEF2K / eEF2 Pathway

Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions

In-Silico Screening-Based Discovery of New Natural eEF2K Inhibitors with Neuritogenic Activity

Deep Hypothermic Low Flow Results in Multiple Aspects of Neurological Deficits in Mice by eEF2 Hyperphosphorylation

Bioinformatic Identification of Risk Factors from an Immunological Viewpoint in Idiopathic Parkinson’s Disease

The gut microbiota in post-stroke depression: A systematic review of microbial mechanisms and therapeutic targeting of neuroinflammation.

Exploring the mechanism of Polygonum Cuspidatum in the treatment of ischemic stroke by network pharmacology analysis and experimental validation.

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation

去甲氧基姜黄素通过促进海马神经发生对阿尔兹海默症认知损伤的改善作用

Tenuigenin ameliorates cognitive dysfunction in Alzheimer’s disease via hippocampal neurogenesis enhancement

Facet-Dependent Activity of CeO2 Nanozymes Regulate the Fate of Human Neural Progenitor Cell via Redox Homeostasis.

ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome

Protective Effect of An-Gong-Niu-Huang Wan Pre-treatment Against Experimental Cerebral Ischemia Injury via Regulating GSK-3β/HO-1 Pathway

Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway

Effects of α-Synuclein-Associated Post-Translational Modifications in Parkinson's Disease.

Interaction of Sp1 and APP promoter elucidates a mechanism for Pb2+ caused neurodegeneration.

20(S)-protopanaxadiol and oleanolic acid ameliorate cognitive deficits in APP/PS1 transgenic mice by enhancing hippocampal neurogenesis

20(S)-protopanaxadiol promotes the migration, proliferation, and differentiation of neural stem cells by targeting GSK-3β in the Wnt/GSK-3β/β-catenin pathway

Traditional Chinese medicine-based neurorestorative therapy for Alzheimer’s and Parkinson’s disease

Parkinson's Disease: Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats (Adv. Sci. 24/2019)

Roles of Glutamate Receptors in Parkinson’s Disease

DCPIB, an Inhibitor of Volume-Regulated Anion Channels, Distinctly Modulates K2P Channels.

Dynamic effect of beta-amyloid 42 on cell mechanics.

Extracellular Nanomatrix‐Induced Self‐Organization of Neural Stem Cells into Miniature Substantia Nigra‐Like Structures with Therapeutic Effects on Parkinsonian Rats

Biophysical Characteristics of Human Neuroblastoma Cell in Oligomeric $\beta $ -Amyloid (1–40) Cytotoxicity

会议论文

龟鹿补肾丸抗阿尔茨海默病的药效学研究

微/纳米塑料青春期暴露对小鼠认知损伤的影响

研究方向