逄大欣｜吉林大学｜学者主页

2026

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

He-Yong Wu, Ao-Si Qi, Shu-Yu Zhong, H. Du, Shimeng Guo, H. Ouyang, Hong-Ming Yuan, Da-Xin Pang, Zi-Cong Xie

Animal Research and One Health

2026

Immunogenicity assessment and epitope mapping of the ASFV proteome by profiling serum antibodies with ASFV antigen phage libraries

Lerong Ma, Zhen Weng, Yuanzhu Zhang, Zhi Cao, Xingjun Ke, Ruize Sun, Yin Xie, Mengjie Lian, Lin Yang, Hongming Yuan, Zi-Cong Xie, H. Ouyang, Da-Xin Pang, Dongmei Lv

Communications Biology

DOI

2026

Whole-Genome Resequencing-Based Selection-Signal and Association Analyses Prioritize Candidate Genes and Haplotypes for PRRS Resistance-Related Traits in Pigs

Mengjie Lian, Jia-Qi Wang, Ai-Shi Xu, Zhi Cao, Shi-Ying Zhou, Hong-Ming Yuan, Zi-Cong Xie, Hong-Sheng Ouyang, Da-Xin Pang, Dongmei Lv

Animals

DOI

2026

PRMT3 restricts porcine epidemic diarrhea virus replication by disrupting the interaction between VAPA and the viral nucleocapsid protein

He-Yong Wu, Shu-Yu Zhong, Ao-Si Qi, Zi-Ru Wang, Qiu-Se Tu, Feng Li, Rui Wu, Jing-Yao Wang, Fan Song, Tian-Yi Zhang, Ting Li, Qing-Chun Yu, Hong-Ming Yuan, Dongmei Lv, Hong-Sheng Ouyang, Xiliang Du, Da-Xin Pang, Zi-Cong Xie

PLoS Pathogens

DOI

2025

Progress Toward Antigenic Epitopes of African Swine Fever Virus and Their Identification

Xingjun Ke, Zhi Cao, Zhen Weng, Yin Xie, Fengyun Wu, Xinzhu Liu, Shi-Ying Zhou, Mengjie Lian, Tongyu Liu, Ruize Sun, Lerong Ma, Ai-Shi Xu, Jiaqi Wang, H. Ouyang, Lin-Zhu Ren, Da-Xin Pang, Dongmei Lv

Transboundary and Emerging Diseases

DOI

2025

Author Correction: Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

Ying Liu, Lin Yang, Hong-Yong Xiang, Ming Niu, Jiacheng Deng, Xueyuan Li, Wen-Jie Hao, Hong-Sheng Ou-Yang, Tong-Yu Liu, Xiaohui Tang, Da-Xin Pang, Hong-Ming Yuan

Zoological Research

DOI

2024

Accelerated discovery and miniaturization of novel single-stranded cytidine deaminases

Jiacheng Deng, Xueyuan Li, Hao Yu, Lin Yang, Zi-Ru Wang, Wen-Feng Yi, Ying Liu, Wenyu Xiao, Hongyong Xiang, Zi-Cong Xie, Dongmei Lv, H. Ouyang, Da-Xin Pang, Hong-Ming Yuan

Nucleic Acids Research

DOI

2024

Regulatory Non-Coding RNAs during Porcine Viral Infections: Potential Targets for Antiviral Therapy

Feng Li, Hao Yu, Ao-Si Qi, Tian-Yi Zhang, Yuran Huo, Qiu-Se Tu, Chunyun Qi, He-Yong Wu, Xi Wang, Jian Zhou, Lanxin Hu, Hong-Sheng Ouyang, Da-Xin Pang, Zi-Cong Xie

Viruses

DOI

2024

Mechanism, structural and functional insights into nidovirus-induced double-membrane vesicles

Xi Wang, Yiwu Chen, Chunyun Qi, Feng Li, Yuanzhu Zhang, Jian Zhou, He-Yong Wu, Tian-Yi Zhang, Ao-Si Qi, Hong-Sheng Ouyang, Zi-Cong Xie, Da-Xin Pang

Frontiers in Immunology

DOI

2024

Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

Ying Liu, Lin Yang, Hong-Yong Xiang, Ming Niu, Jiacheng Deng, Xueyuan Li, Wen-Jie Hao, Hong-Sheng Ouyang, Tong-Yu Liu, Xiao-Chun Tang, Da-Xin Pang, Hong-Ming Yuan

Zoological Research

DOI

2024

Effective inhibition of PDCoV infection in chimeric APN gene-edited neonatal pigs

Ji-Zong Li, Jian Zhou, Tian-Yi Zhang, He-Yong Wu, Feng Li, Chunyun Qi, Liyuan Fan, Xuesong Yuan, Wei Wang, Rongli Guo, B. Fan, Xiao-Chun Tang, Da-Xin Pang, H. Ouyang, Zi-Cong Xie, Bin Li

Journal of Virology

DOI

2024

Yeast β-glucan promotes antiviral type I interferon response via dectin-1.

Jia-Qi Wang, Xuemin Jin, Shihan Yan, Haoran Zhao, Da-Xin Pang, Hong-Sheng Ouyang, Xiao-Chun Tang

Veterinary Microbiology

DOI

2024

Identification of porcine PARP11 as a restricted factor for pseudorabies virus

Chunyun Qi, Dehua Zhao, Xi Wang, Lanxin Hu, Yao Wang, He-Yong Wu, Feng Li, Jian Zhou, Tian-Yi Zhang, Ao-Si Qi, Yuran Huo, Qiu-Se Tu, Shuyu Zhong, Hong-Ming Yuan, Dongmei Lv, Shou-Qing Yan, H. Ouyang, Da-Xin Pang, Zi-Cong Xie

Frontiers in Cellular and Infection Microbiology

DOI

2023

Decreasing predictable DNA off-target effects and narrowing editing windows of adenine base editors by fusing human Rad18 protein variant

Ziru Wang, Hongming Yuan, Lin Yang, Lerong Ma, Yuan‐Zhu Zhang, Jiacheng Deng, Xueyuan Li, Wenyu Xiao, Zhanjun Li, Jiazhang Qiu, Hongsheng Ouyang, Daxin Pang

International Journal of Biological Macromolecules

DOI

2023

Transmissible Gastroenteritis Virus: An Update Review and Perspective

Yiwu Chen, Yuanzhu Zhang, Xi Wang, Jian Zhao Zhou, Lerong Ma, Jianing Li, Lin Yang, Hongsheng Ouyang, Hongming Yuan, Daxin Pang

Viruses

DOI

2022

Generation of APN-chimeric gene-edited pigs by CRISPR/Cas9-mediated knock-in strategy

Zhenying Liu, Mingjun Zhang, Peixuan Huang, Zhaoyang Ji, Chunyun Qi, Shuyu Jiao, Dehua Zhao, Yuan Jiang, Xue Chen, Dongmei Lv, Daxin Pang, Xin Zhang, Li Feng, Zicong Xie, Hongsheng Ouyang

Gene

DOI

2022

Generation of PCBP1-deficient pigs using CRISPR/Cas9-mediated gene editing

Chunyun Qi, Daxin Pang, Kang Yang, Shuyu Jiao, Heyong Wu, Chuheng Zhao, Lanxin Hu, Feng Li, Jian Zhou, Lin Yang, Dongmei Lv, Xiaochun Tang, Hongsheng Ouyang, Zicong Xie

iScience

DOI

2022

Porcine Epidemic Diarrhea Virus: An Updated Overview of Virus Epidemiology, Virulence Variation Patterns and Virus–Host Interactions

Yuanzhu Zhang, Yiwu Chen, Jian Zhao Zhou, Xi Wang, Lerong Ma, Jianing Li, Lin Yang, Hongming Yuan, Daxin Pang, Hongsheng Ouyang

Viruses

DOI

2022

Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis

Xiaodong Zou, Yang Yang, Lin Feng, Jiahuan Chen, Huanyu Zhang, Linquan Li, Hongsheng Ouyang, Daxin Pang, Linzhu Ren, Xiaochun Tang

iScience

DOI

2022

Advance of genetically modified pigs in xeno-transplantation

Jiacheng Deng, Lin Yang, Ziru Wang, Hongsheng Ouyang, Hao Yu, Hongming Yuan, Daxin Pang

Frontiers in Cell and Developmental Biology

DOI

2022

Cholesterol Biosynthesis Modulates CSFV Replication

Xiaodong Zou, Lin Feng, Yang Yang, Jiahuan Chen, Huanyu Zhang, Linquan Li, Hongsheng Ouyang, Daxin Pang, Xiaochun Tang

Viruses

DOI

2022

Porcine ZC3H11A Is Essential for the Proliferation of Pseudorabies Virus and Porcine Circovirus 2

Lin Yang, Ziru Wang, Hongsheng Ouyang, Yuan‐Zhu Zhang, Wenyu Xiao, Ying Liu, Jiacheng Deng, Mengjing Li, Lerong Ma, Chunyun Qi, Daxin Pang, Hongming Yuan

ACS Infectious Diseases

DOI

2022

AbSE Workflow: Rapid Identification of the Coding Sequence and Linear Epitope of the Monoclonal Antibody at the Single-cell Level

Lerong Ma, Hongsheng Ouyang, Ang Su, Yuan‐Zhu Zhang, Daxin Pang, Tao Zhang, Ruize Sun, Wentao Wang, Zicong Xie, Dongmei Lv

ACS Synthetic Biology

DOI

2022

Current Status of Genetically Modified Pigs That Are Resistant to Virus Infection

Hongming Yuan, Lin Yang, Yuanzhu Zhang, Wenyu Xiao, Ziru Wang, Xiaochun Tang, Hongsheng Ouyang, Daxin Pang

Viruses

DOI

2022

Identification and Functional Analysis of the Regulatory Elements in the pHSPA6 Promoter

Shuyu Jiao, Chunyan Bai, Chunyun Qi, Heyong Wu, Lanxin Hu, Feng Li, Kang Yang, Chuheng Zhao, Hongsheng Ouyang, Daxin Pang, Xiaochun Tang, Zicong Xie

Genes

DOI

2021

HMEJ-mediated site-specific integration of a myostatin inhibitor increases skeletal muscle mass in porcine

Mengjing Li, Xiao-Chun Tang, Wenni You, Yanbing Wang, Yiwu Chen, Ying Liu, Hong-Ming Yuan, Chuang Gao, Xue Chen, Zhi-Hong Xiao, Hong-Sheng Ouyang, Da-Xin Pang

Molecular Therapy: Nucleic Acids

DOI

2021

CRISPR/Cas9-Mediated Specific Integration of Fat-1 and IGF-1 at the pRosa26 Locus

Wenni You, Mengjing Li, Yilin Qi, Yanbing Wang, Yiwu Chen, Ying Liu, Li Li, Hongsheng Ouyang, Daxin Pang

Genes

DOI

2021

Generation and characterization of stable pig pregastrulation epiblast stem cell lines

Minglei Zhi, Jinying Zhang, Qianzi Tang, Dawei Yu, Shuai Gao, Dengfeng Gao, Pengliang Liu, Jianxiong Guo, Tang Hai, Jie Gao, Suying Cao, Zimo Zhao, Chongyang Li, Xiaogang Weng, Mengnan He, Tianzhi Chen, Yingjie Wang, Keren Long, Deling Jiao, Guanglei Li, Jiaman Zhang, Yan Liu, Yu Lin, Daxin Pang, Qianqian Zhu, Naixin Chen, Jingjing Huang, Xinze Chen, Yixuan Yao, Jingcang Yang, Zicong Xie, Xianya Huang, Mengxin Liu, Ran Zhang, Qiuyan Li, Yi‐Liang Miao, Jianhui Tian, Xingxu Huang, Hongsheng Ouyang, Bofeng Liu, Wei Xie, Qi Zhou, Hong‐Jiang Wei, Zhonghua Liu, Caihong Zheng, Mingzhou Li, Jianyong Han

Cell Research

DOI

2021

Investigation of the lncRNA THOR in Mice Highlights the Importance of Noncoding RNAs in Mammalian Male Reproduction

Lin Zhou, Jianing Li, Jinsong Liu, Anbei Wang, Ying Liu, Hao Yu, Hongsheng Ouyang, Daxin Pang

Biomedicines

DOI

2021

Pathological alterations in the gastrointestinal tract of a porcine model of DMD

Xiaodong Zou, Hongsheng Ouyang, Daxin Pang, Renzhi Han, Xiaochun Tang

Cell & Bioscience

DOI

2020

CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs

Jiahuan Chen, Beiying An, Biao Yu, Xiaohuan Peng, Hongming Yuan, Qiangbing Yang, Xue Chen, Tingting Yu, Lingyu Wang, Xinwei Zhang, He Wang, Xiaodong Zou, Daxin Pang, Hongsheng Ouyang, Xiaochun Tang

Haematologica

DOI

2020

Generation of a pHSPA6 gene-based multifunctional live cell sensor

Zicong Xie, Ruize Sun, Chunyun Qi, Shuyu Jiao, Yuan Jiang, Zhenying Liu, Dehua Zhao, Ruonan Liu, Qirong Li, Kang Yang, Lanxin Hu, Xinping Wang, Xiaochun Tang, Hongsheng Ouyang, Daxin Pang

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

DOI

2020

Investigation on the Effect of Two Fat Metabolism Related Pathways on Intramuscular Fat Content in Pigs

Chaogang Yao, Daxin Pang, Chao Lu, Aishi Xu, Peixuan Huang, Hongsheng Ouyang, Hao Yu

Pakistan Journal of Zoology

DOI

2020

A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans

Boyan Zhang, Chenyu Wang, Yue Zhang, Yuan Jiang, Yanguo Qin, Daxin Pang, Guizhen Zhang, He Liu, Zicong Xie, Hongming Yuan, Hongsheng Ouyang, Jincheng Wang, Xiaochun Tang

Bone

DOI

2019

DNA甲基化和组蛋白修饰在兔早期胚胎的动态分析

王安峰，黄永业，逄大欣

《吉林农业大学学报》

DOI

2019

Generation of pRSAD2 gene knock-in pig via CRISPR/Cas9 technology

Zicong Xie, Huping Jiao, Haonan Xiao, Yuan Jiang, Zhenying Liu, Chunyun Qi, Dehua Zhao, Shuyu Jiao, Tingting Yu, Xiaochun Tang, Daxin Pang, Hongsheng Ouyang

Antiviral Research

DOI

2019

Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system

Xiaodong Zou, Hongsheng Ouyang, Tingting Yu, Xue Chen, Daxin Pang, Xiaochun Tang, Chengzhen Chen

Cell Death and Disease

DOI

2019

CRISPR/Cas9-Mediated Hitchhike Expression of Functional shRNAs at the Porcine miR-17-92 Cluster

Chao Lu, Daxin Pang, Mengjing Li, Hongming Yuan, Tingting Yu, Peixuan Huang, Jianing Li, Xue Chen, Huping Jiao, Zicong Xie, Hongsheng Ouyang

Cells

DOI

2019

Efficient base editing by RNA-guided cytidine base editors (CBEs) in pigs

Hongming Yuan, Tingting Yu, Lingyu Wang, Lin Yang, Yuanzhu Zhang, Huan Liu, Mengjing Li, Xiaochun Tang, Zhiquan Liu, Zhanjun Li, Chao Lu, Xue Chen, Daxin Pang, Hongsheng Ouyang

Cellular and Molecular Life Sciences

DOI

2019

Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins

Ting Ouyang, Guyu Niu, Yifang Zhang, Xiaohua Liu, Xinwei Zhang, Shiqi Zhang, Yulu Geng, Daxin Pang, Hongsheng Ouyang, Linzhu Ren

Viruses

DOI

2019

Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro

Xiaohui Liu, Ting Ouyang, Hongsheng Ouyang, Xiaohua Liu, Guyu Niu, Wang Huo, Weihong Yin, Daxin Pang, Linzhu Ren

Scientific Reports

DOI

2019

Development of Whole-Porcine Monoclonal Antibodies with Potent Neutralization Activity against Classical Swine Fever Virus from Single B Cells

Haisi Dong, Ang Su, Dongmei Lv, Lerong Ma, Jianwei Dong, Nannan Guo, Linzhu Ren, Huping Jiao, Daxin Pang, Hongsheng Ouyan

ACS Synthetic Biology

DOI

2019

Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs

Chaogang Yao, Daxin Pang, Chao Lu, Aishi Xu, Peixuan Huang, Hongsheng Ouyang, Hao Yu

Animals

DOI

2019

The Possible Role of Complete Loss of Myostatin in Limiting Excessive Proliferation of Muscle Cells (C2C12) via Activation of MicroRNAs

Peixuan Huang, Daxin Pang, Kankan Wang, Aishi Xu, Chaogang Yao, Mengjing Li, Wenni You, Qiushuang Wang, Hao Yu

International Journal of Molecular Sciences

DOI

2018

Subculturing cells have no effect on CRISPR/Cas9‐mediated cleavage of UL30 gene in pseudorabies virus

Linzhu Ren, Zhiyuan Peng, Ting Ouyang, Xiaohui Liu, Xin‐rong Chen, Li Ye, Junwen Fan, Hongsheng Ouyang, Daxin Pang, Jieying Bai

Animal Models and Experimental Medicine

DOI

2018

Genetically modified pigs are protected from classical swine fever virus

Zicong Xie, Daxin Pang, Hongming Yuan, Huping Jiao, Chao Lu, Kankan Wang, Qiangbing Yang, Mengjing Li, Xue Chen, Tingting Yu, Xinrong Chen, Zhen Dai, Yani Peng, Xiaochun Tang, Zhanjun Li, Tiedong Wang, Huancheng Guo, Li Li, Changchun Tu, Liangxue Lai, Hongsheng Ouyang

PLoS Pathogens

DOI

2018

Immunogenicity evaluation of inactivated virus and purified proteins of porcine circovirus type 2 in mice

Xiaohui Liu, Ting Ouyang, Teng Ma, Hongsheng Ouyang, Daxin Pang, Linzhu Ren

BMC Veterinary Research

DOI

2018

Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs

Mengjing Li, Hongsheng Ouyang, Hongming Yuan, Jianing Li, Zicong Xie, Kankan Wang, Tingting Yu, Minghao Liu, Xue Chen, Xiaochun Tang, Huping Jiao, Daxin Pang

G3 Genes Genomes Genetics

DOI

2017

CRISPR/Cas9-mediated knockout of myostatin in Chinese indigenous Erhualian pigs

Kankan Wang, Xiaochun Tang, Zicong Xie, Xiaodong Zou, Mengjing Li, Hongming Yuan, Nannan Guo, Hongsheng Ouyang, Huping Jiao, Daxin Pang

Transgenic Research

DOI

2017

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

Zicong Xie, Daxin Pang, Kankan Wang, Mengjing Li, Nannan Guo, Hongming Yuan, Jianing Li, Xiaodong Zou, Huping Jiao, Hongsheng Ouyang, Zhanjun Li, Xiaochun Tang

Scientific Reports

DOI

2017

Characterization and comparative analysis of immunoglobulin lambda chain diversity in a neonatal porcine model

Nannan Guo, Menghan Su, Zicong Xie, Kankan Wang, Hongming Yuan, Mengjing Li, Jianing Li, Minghao Liu, Jing Bai, Jing Liu, Hongsheng Ouyang, Daxin Pang, Huping Jiao

Veterinary Immunology and Immunopathology

DOI

2016

HMGCR inhibits the early stage of PCV2 infection, while PKC enhances the infection at the late stage*

Teng Ma, Xinrong Chen, Hongsheng Ouyang, Xiaohui Liu, Ting Ouyang, Zhiyuan Peng, Xin Yang, Fuwang Chen, Daxin Pang, Jieying Bai, Linzhu Ren

Virus Research

DOI

2016

Porcine circovirus 2 proliferation can be enhanced by stably expressing porcine IL-2 gene in PK-15 cell

Teng Ma, Ting Ouyang, Hongsheng Ouyang, Fuwang Chen, Zhiyuan Peng, Xinrong Chen, Daxin Pang, Linzhu Ren

Virus Research

DOI

2016

WITHDRAWN: Crossbred Commercial Pigs immunoglobulin lambda chain usage diversity fluctuation after born

Nannan Guo, Huping Jiao, Zicong Xie, Kankan Wang, Jing Bai, Hongming Yuan, Mengjing Li, Jianing Li, Minghao Liu, Hongsheng Ouyang, Daxin Pang

Veterinary Immunology and Immunopathology

DOI

2016

Pseudorabies virus can escape from CRISPR-Cas9-mediated inhibition

Zhiyuan Peng, Ting Ouyang, Daxin Pang, Teng Ma, Xinrong Chen, Ning Guo, Fuwang Chen, Lin Yuan, Hongsheng Ouyang, Linzhu Ren

Virus Research

DOI

2016

N-3 polyunsaturated fatty acids attenuates triglyceride and inflammatory factors level in hfat-1 transgenic pigs

Xingxing Liu, Daxin Pang, Ting Yuan, Zhuang Li, Zhanjun Li, Mingjun Zhang, Wenzhi Ren, Hongsheng Ouyang, Xiaochun Tang

Lipids in Health and Disease

DOI

2016

Chimerism in piglets developed from aggregated cloned embryos

Yongye Huang, Zhanjun Li, Anfeng Wang, Xiaolei Han, Yuning Song, Lin Yuan, Tianye Li, Bing Wang, Liangxue Lai, Hongsheng Ouyang, Daxin Pang

FEBS Open Bio

DOI

2016

Expression, purification and antibody preparation of PCV2 Rep and ORF3 proteins

Zhiyuan Peng, Teng Ma, Daxin Pang, Dan Su, Fuwang Chen, Xinrong Chen, Ning Guo, Ting Ouyang, Hongsheng Ouyang, Linzhu Ren

International Journal of Biological Macromolecules

DOI

2016

Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair

Kankan Wang, Xiaochun Tang, Yan Liu, Zicong Xie, Xiaodong Zou, Mengjing Li, Hongming Yuan, Hongsheng Ouyang, Huping Jiao, Daxin Pang

Molecular Therapy — Nucleic Acids

DOI

2015

Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System

Kankan Wang, Hongsheng Ouyang, Zicong Xie, Chaogang Yao, Nannan Guo, Mengjing Li, Huping Jiao, Daxin Pang

Scientific Reports

DOI

2015

Germ cell‐specific expression of Cre recombinase using the VASA promoter in the pig

Yuning Song, Liangxue Lai, Li Li, Yongye Huang, Anfeng Wang, Xiaochun Tang, Daxin Pang, Zhanjun Li, Hongsheng Ouyang

FEBS Open Bio

DOI

2015

Overexpression of porcine lipoprotein-associated phospholipase A 2 in swine

Xiaochun Tang, Gangqi Wang, Xingxing Liu, Xiaolei Han, Zhuang Li, Guangyao Ran, Zhanjun Li, Qi Song, Yuan Ji, Haijun Wang, Yuhui Wang, Hongsheng Ouyang, Daxin Pang

Biochemical and Biophysical Research Communications

DOI

2015

Development of a Rapid Method for the Visible Detection of Pork DNA in Halal Products by Loop-Mediated Isothermal Amplification

Guangyao Ran, Linzhu Ren, Xiaolei Han, Xingxing Liu, Zhuang Li, Daxin Pang, Hongsheng Ouyang, Xiaochun Tang

Food Analytical Methods

DOI

2015

Valproic Acid Improves Porcine Parthenogenetic Embryo Development Through Transient Remodeling of Histone Modifiers

Yongye Huang, Lin Yuan, Tianye Li, Anfeng Wang, Zhanjun Li, Daxin Pang, Bing Wang, Hongsheng Ouyang

Cellular Physiology and Biochemistry

DOI

2014

HSP27和Annexin A2蛋白对PRRSV感染的影响

曹宇航，王斐，刘晓云，张潇，逄大欣，张明军，任林柱

《中国兽医学报》

2014

高效抗猪瘟病毒shRNA的筛选

戴祯，王铁东，王侃侃，欧阳红生，涂长春，逄大欣

《中国兽医学报》

2014

Overexpression of NPC1L1 in the livers of transgenic Bama miniature pigs accelerates lipid peroxidation

Chongli Xu, Yu Xin Liu, Yuchen Gong, Xinping Duan, Xiaochun Tang, Mingjun Zhang, Daxin Pang, Liqing Yu, Hong Kui WEI, Hongsheng Ouyang

Genes & Genomics

DOI

2013

猪MSTN基因敲除载体的构建及细胞筛选

高飞，唐成程，全龙泉，戴祯，苏佰通，赖良学，逄大欣，欧阳红生

《中国兽医学报》

2013

猪肌生成抑制素单克隆抗体的制备及鉴定

车东升，张春，李占军，李莉，逄大欣，欧阳红生

《吉林农业大学学报》

2013

新生长白仔猪尾尖成纤维细胞的分离培养及其对猪瘟病毒的易感性分析

武蓉，戴祯，赵致阳，高飞，全龙泉，逄大欣，王铁东，涂长春，欧阳红生

《中国兽医学报》

2013

Efficiency of porcine somatic cell nuclear transfer – a retrospective study of factors related to embryo recipient and embryos transferred

Yongye Huang, Hongsheng Ouyang, Hao Yu, Liangxue Lai, Daxin Pang, Zhanjun Li

Biology Open

DOI

2013

Scriptaid affects histone acetylation and the expression of development-related genes at different stages of porcine somatic cell nuclear transfer embryo during early development

Yan Zhou, Yongye Huang, Wanhua Xie, Qi Song, Yuan Ji, Yanping Zhang, Hongsheng Ouyang, Liangxue Lai, Daxin Pang, Xiaochun Tang

Chinese Science Bulletin

DOI

2013

Aberrant expression of Igf2/H19 in porcine parthenogenetic fetuses and placentas

Xiaolei Han, Hongsheng Ouyang, Xianju Chen, Yongye Huang, Yuning Song, Mingjun Zhang, Daxin Pang, Liangxue Lai, Zhanjun Li

Animal Reproduction Science

DOI

2013

Moderate expression of Wnt signaling genes is essential for porcine parthenogenetic embryo development

Yongye Huang, Hongsheng Ouyang, Wanhua Xie, Xianju Chen, Chaogang Yao, Yang Han, Xiaolei Han, Qi Song, Daxin Pang, Xiaochun Tang

Cellular Signalling

DOI

2012

茎环法RT-qPCR定量检测细胞抗猪瘟病毒siRNA的表达

刘帅，李江南，袁婷，杨凡力，逄大欣，涂长春

《生物工程学报》

2012

PIWIL1基因启动子调控的特异表达Cre重组酶的转基因猪的构建

段新平，高飞，全龙泉，唐成程，武蓉，戴祯，欧阳红生，逄大欣

《畜牧与兽医》

2012

慢病毒介导的猪CD4启动子在白血病Jurkat细胞中的启动作用

林晓晨，杨鑫，曹宇航，焦丽，戴甄，任林柱，逄大欣

《吉林大学学报(医学版)》

DOI

2012

热休克蛋白在抗病毒免疫中作用的研究进展

杨鑫，陈福旺，曹宇航，逄大欣，欧阳红生，任林柱

《畜牧与兽医》

2012

骨骼肌特异性表达猪FSⅠ-Ⅰ转基因猪胚胎成纤维细胞克隆的构建与鉴定

袁婷，刘帅，李小平，唐成程，韩晓蕾，逄大欣，欧阳红生

《吉林大学学报(医学版)》

2012

RNAi的毒性研究进展

戴祯，武蓉，高飞，姚潮刚，韩杨，唐成程，赵致阳，逄大欣

《畜牧与兽医》

2012

猪MSTN基因敲除载体的构建

高飞，唐成程，全龙泉，武蓉，戴祯，欧阳红生，逄大欣

《畜牧与兽医》

2012

单胚胎RT-qPCR对猪体细胞核移植囊胚全能性的分析

谢万华，陈仙菊，姚朝刚，韩阳，逄大欣，唐晓春

《中国饲料》

2012

Annexin A2在病毒感染中的作用

陈福旺，张田，曹宇航，杨鑫，逄大欣，欧阳红生，任林柱

《畜牧与兽医》

2012

组蛋白去乙酰化酶抑制剂Scriptaid对猪孤雌胚胎体外发育能力的影响

姚潮刚，戴祯，韩杨，韩晓蕾，逄大欣，李占军

《畜牧与兽医》

2012

哺乳动物的印记基因

韩晓蕾，姚潮刚，韩杨，高鹏飞，逄大欣，李占军

《畜牧与兽医》

2012

Direct Conversion of Porcine Embryonic Fibroblasts into Adipocytes by Chemical Molecules

Jianguo Zhu, Daxin Pang, Yang Zhou, Xiaochun Tang, Yongye Huang, Wanhua Xie, Fei Gao, Liangxue Lai, Mingjun Zhang, Hongsheng Ouyang

Cellular Reprogramming

DOI

2012

Start effect of lentiviral vector-mediated CD4 gene promoter in leukemia Jurkat cells

Daxin Pang

Journal of Jilin University

2011

Fat-1基因真核表达载体的构建及其对人口腔鳞癌细胞脂肪酸含量的影响

李栋，聂代邦，王海军，段新平，逄大欣，欧阳红生

《现代生物医学进展》

2011

表达Cre重组酶Cre-pCEP4载体的构建及其在Cre/loxP重组系统中的应用

周杨，朱建国，唐小春，闫森，宋娜，张明军，李莉，欧阳红生，逄大欣

《吉林大学学报(医学版)》

2011

Histone Deacetylase Inhibitor Significantly Improved the Cloning Efficiency of Porcine Somatic Cell Nuclear Transfer Embryos

Yongye Huang, Xiaochun Tang, Wanhua Xie, Yan Zhou, Dong Li, Chaogang Yao, Yang Zhou, Jianguo Zhu, Liangxue Lai, Hongsheng Ouyang, Daxin Pang

Cellular Reprogramming

DOI

2011

Characterization of a hypertriglyceridemic transgenic miniature pig model expressing human apolipoprotein CIII

Jingyuan Wei, Hongsheng Ouyang, Yuhui Wang, Daxin Pang, Nathan Cong, Tiedong Wang, Bingfeng Leng, Dong Li, Xiaoping Li, Rong Wu, Yu‐Qiang Ding, Fei Gao, Yanhong Deng, Bo Liu, Ziyi Li, Liangxue Lai, Haihua Feng, Chaojie Liu, Xuming Deng

FEBS Journal

DOI

2011

Production of cloned transgenic cow expressing omega-3 fatty acids

Xia Wu, Hongsheng Ouyang, Duan Biao, Daxin Pang, Li Zhang, Ting Yuan, Lian Xue, Daibang Ni, Lei Cheng, Shuhua Dong, Zhuying Wei, Lin Li, Ming Yu, Qing‐Yuan Sun, Da‐Yuan Chen, Liangxue Lai, Yifan Dai, Guangpeng Li

Transgenic Research

DOI

2011

Vitamin C enhances in vitro and in vivo development of porcine somatic cell nuclear transfer embryos

Yongye Huang, Xiaochun Tang, Wanhua Xie, Yan Zhou, Dong Li, Yang Zhou, Jianguo Zhu, Ting Yuan, Liangxue Lai, Daxin Pang, Hongsheng Ouyang

Biochemical and Biophysical Research Communications

DOI

2011

Isolation and culture of embryonic stem-like cells from pig nuclear transfer blastocysts of different days

Guangyun Tan, Linzhu Ren, Yongye Huang, Xiaochun Tang, Yang Zhou, Yan Zhou, Dong Li, Hongxiao Song, Hongsheng Ouyang, Daxin Pang

Zygote

DOI

2011

Human MxA protein inhibits the replication of classical swine fever virus

Yicheng Zhao, Daxin Pang, Tiedong Wang, Xin Yang, Rong Wu, Linzhu Ren, Ting Yuan, Yongye Huang, Hongsheng Ouyang

Virus Research

DOI

2011

Comparative analysis of the activity of two promoters in insect cells

Ren Linzhu, Pang DaXin, Zhang Mingjun, Li Li, Wang Tiedong, Ouyang Hongsheng, LI Ai-min

AFRICAN JOURNAL OF BIOTECHNOLOGY

DOI

2010

与细胞衰老相关的sirtuin家族

朱建国，周杨，段新平，逄大欣，欧阳红生

《生命的化学》

2010

绿色荧光小鼠胚胎干细胞的分离与培养

谭广云，谢万华，周焱，黄永业，宋红肖，李栋，宋娜，袁婷，段新平，逄大欣，欧阳红生

《现代生物医学进展》

2010

hiTAIL-PCR技术鉴定转基因猪整合位点的研究

李莉，李小平，任林柱，陈立梅，王铁东，张英，闫森，欧阳红生，逄大欣

《中国兽医学报》

2009

抗菌肽天蚕素B基因的克隆及其在山羊乳腺中的暂态表达

王铁东，李小平，逄大欣，欧阳红生

《中国兽医学报》

2009

诱导性表达Cre重组酶转基因猪成纤维细胞的构建及鉴定

陈立梅，逄大欣，李莉，李占军，杨春，聂代邦，欧阳红生

《中国兽医学报》

2009

Establishment of a Transgenic Pig Fetal Fibroblast Reporter Cell Line for Monitoring Cre Recombinase Activity

Li Li, Daxin Pang, Limei Chen, Tiedong Wang, Daibang Nie, Sen Rong Yan, Hongsheng Ouyang

DNA and Cell Biology

DOI

2009

Production of a reporter transgenic pig for monitoring Cre recombinase activity

Li Li, Daxin Pang, Tiedong Wang, Zhanjun Li, Limei Chen, Mingjun Zhang, Na Song, Daibang Nie, Zhenwen Chen, Liangxue Lai, Hongsheng Ouyang

Biochemical and Biophysical Research Communications

DOI

2008

Cre基因拼接及转基因细胞的构建

毛丹，逄大欣，聂代邦，吴婷婷，欧阳红生

《中国科技信息》

2007

体外培养枫径猪胚胎成纤维细胞系方法的建立

陈颖，逄大欣，车东升，赵增明，赖良学，欧阳红生

《吉林农业大学学报》

2006

猪肌生成抑制素作用靶位点的研究

逄大欣

《吉林大学》

精选作品

期刊论文

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Immunogenicity assessment and epitope mapping of the ASFV proteome by profiling serum antibodies with ASFV antigen phage libraries

Whole-Genome Resequencing-Based Selection-Signal and Association Analyses Prioritize Candidate Genes and Haplotypes for PRRS Resistance-Related Traits in Pigs

PRMT3 restricts porcine epidemic diarrhea virus replication by disrupting the interaction between VAPA and the viral nucleocapsid protein

Progress Toward Antigenic Epitopes of African Swine Fever Virus and Their Identification

Author Correction: Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

Accelerated discovery and miniaturization of novel single-stranded cytidine deaminases

Regulatory Non-Coding RNAs during Porcine Viral Infections: Potential Targets for Antiviral Therapy

Mechanism, structural and functional insights into nidovirus-induced double-membrane vesicles

Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

Effective inhibition of PDCoV infection in chimeric APN gene-edited neonatal pigs

Yeast β-glucan promotes antiviral type I interferon response via dectin-1.

Identification of porcine PARP11 as a restricted factor for pseudorabies virus

Decreasing predictable DNA off-target effects and narrowing editing windows of adenine base editors by fusing human Rad18 protein variant

Transmissible Gastroenteritis Virus: An Update Review and Perspective

Generation of APN-chimeric gene-edited pigs by CRISPR/Cas9-mediated knock-in strategy

Generation of PCBP1-deficient pigs using CRISPR/Cas9-mediated gene editing

Porcine Epidemic Diarrhea Virus: An Updated Overview of Virus Epidemiology, Virulence Variation Patterns and Virus–Host Interactions

Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis

Advance of genetically modified pigs in xeno-transplantation

Cholesterol Biosynthesis Modulates CSFV Replication

Porcine ZC3H11A Is Essential for the Proliferation of Pseudorabies Virus and Porcine Circovirus 2

AbSE Workflow: Rapid Identification of the Coding Sequence and Linear Epitope of the Monoclonal Antibody at the Single-cell Level

Current Status of Genetically Modified Pigs That Are Resistant to Virus Infection

Identification and Functional Analysis of the Regulatory Elements in the pHSPA6 Promoter

HMEJ-mediated site-specific integration of a myostatin inhibitor increases skeletal muscle mass in porcine

CRISPR/Cas9-Mediated Specific Integration of Fat-1 and IGF-1 at the pRosa26 Locus

Generation and characterization of stable pig pregastrulation epiblast stem cell lines

Investigation of the lncRNA THOR in Mice Highlights the Importance of Noncoding RNAs in Mammalian Male Reproduction

Pathological alterations in the gastrointestinal tract of a porcine model of DMD

CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs

Generation of a pHSPA6 gene-based multifunctional live cell sensor

Investigation on the Effect of Two Fat Metabolism Related Pathways on Intramuscular Fat Content in Pigs

A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans

DNA甲基化和组蛋白修饰在兔早期胚胎的动态分析

Generation of pRSAD2 gene knock-in pig via CRISPR/Cas9 technology

Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system

CRISPR/Cas9-Mediated Hitchhike Expression of Functional shRNAs at the Porcine miR-17-92 Cluster

Efficient base editing by RNA-guided cytidine base editors (CBEs) in pigs

Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins

Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro

Development of Whole-Porcine Monoclonal Antibodies with Potent Neutralization Activity against Classical Swine Fever Virus from Single B Cells

Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs

The Possible Role of Complete Loss of Myostatin in Limiting Excessive Proliferation of Muscle Cells (C2C12) via Activation of MicroRNAs

Subculturing cells have no effect on CRISPR/Cas9‐mediated cleavage of UL30 gene in pseudorabies virus

Genetically modified pigs are protected from classical swine fever virus

Immunogenicity evaluation of inactivated virus and purified proteins of porcine circovirus type 2 in mice

Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs

CRISPR/Cas9-mediated knockout of myostatin in Chinese indigenous Erhualian pigs

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

Characterization and comparative analysis of immunoglobulin lambda chain diversity in a neonatal porcine model

HMGCR inhibits the early stage of PCV2 infection, while PKC enhances the infection at the late stage*

Porcine circovirus 2 proliferation can be enhanced by stably expressing porcine IL-2 gene in PK-15 cell

WITHDRAWN: Crossbred Commercial Pigs immunoglobulin lambda chain usage diversity fluctuation after born

Pseudorabies virus can escape from CRISPR-Cas9-mediated inhibition

N-3 polyunsaturated fatty acids attenuates triglyceride and inflammatory factors level in hfat-1 transgenic pigs

Chimerism in piglets developed from aggregated cloned embryos

Expression, purification and antibody preparation of PCV2 Rep and ORF3 proteins

Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair

Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System

Germ cell‐specific expression of Cre recombinase using the VASA promoter in the pig

Overexpression of porcine lipoprotein-associated phospholipase A 2 in swine

Development of a Rapid Method for the Visible Detection of Pork DNA in Halal Products by Loop-Mediated Isothermal Amplification

Valproic Acid Improves Porcine Parthenogenetic Embryo Development Through Transient Remodeling of Histone Modifiers

HSP27和Annexin A2蛋白对PRRSV感染的影响

高效抗猪瘟病毒shRNA的筛选

Overexpression of NPC1L1 in the livers of transgenic Bama miniature pigs accelerates lipid peroxidation

猪MSTN基因敲除载体的构建及细胞筛选

猪肌生成抑制素单克隆抗体的制备及鉴定

新生长白仔猪尾尖成纤维细胞的分离培养及其对猪瘟病毒的易感性分析

Efficiency of porcine somatic cell nuclear transfer – a retrospective study of factors related to embryo recipient and embryos transferred

Scriptaid affects histone acetylation and the expression of development-related genes at different stages of porcine somatic cell nuclear transfer embryo during early development

Aberrant expression of Igf2/H19 in porcine parthenogenetic fetuses and placentas

Moderate expression of Wnt signaling genes is essential for porcine parthenogenetic embryo development

茎环法RT-qPCR定量检测细胞抗猪瘟病毒siRNA的表达

PIWIL1基因启动子调控的特异表达Cre重组酶的转基因猪的构建

慢病毒介导的猪CD4启动子在白血病Jurkat细胞中的启动作用

热休克蛋白在抗病毒免疫中作用的研究进展