宋瑞｜中国药科大学｜学者主页

2026

集成靶向和拟靶向策略测定健康及溃疡性结肠炎小鼠体内四逆散原型成分及代谢物

曹艳芳，郑媛，陈永顺，李思翰，冯凯，李兴佳，宋瑞

《中国药科大学学报》

2025

溃疡性结肠炎小鼠结肠及免疫组织中四逆散药源性成分的LC-MS分析

曹艳芳，汪雅莉，王安慧，陈永顺，李思翰，冯凯，杨婉薇，宋瑞

《中国药科大学学报》

2024

“拔尖计划”2.0背景下药物质量分析与控制课程建设

叶宝芬，宋瑞

《药学教育》

2023

非酒精性脂肪性肝病细胞模型中胆固醇代谢紊乱机制

章玉婷，王安慧，杨晋妮，林佳纯，田媛，董海娟，张尊建，宋瑞

《中国药科大学学报》

2023

Study on the effect of calibration standards prepared with different matrix on the accuracy of bile acid quantification using LC-MS/MS

Jinni Yang, Jia‐Chun Lin, Anhui Wang, Xue Yang, Xue Yang, Yuting Zhang, Yali Wang, Yuting Zhang, Yuting Zhang, Haijuan Dong, Yuan Tian, Zunjian Zhang, Min Wang, Rui Song

Journal of Pharmaceutical and Biomedical Analysis

DOI

2022

柴胡皂苷d的体内外肠道吸收机制研究

邢媛月，任偲琪，刘奇玮，杨晋妮，董海娟，宋瑞，张尊建

《中国药科大学学报》

2021

药源性糖尿病发病机制的研究进展

徐杰，王敏，宋瑞，葛卫红，张尊建

《药学进展》

2021

Saikosaponins and the deglycosylated metabolites exert liver meridian guiding effect through PXR/CYP3A4 inhibition

Qiwei Liu, Yunwen Xue, Jingjing Liu, Siqi Ren, Jie Xu, Jinni Yang, Yuanyue Xing, Zunjian Zhang, Rui Song

Journal of Ethnopharmacology

DOI

2020

Corrigendum to “Pharmacokinetics and oral bioavailability studies of three saikogenins in rats using a validated UFLC-MS/MS method” [J. Chromatogr. B 1124 (2019) 265–272]

Jingjing Liu, Yunwen Xue, Jianbo Sun, Rui‐Jia Fu, Siqi Ren, Zunjian Zhang, Rui Song

Journal of Chromatography B

DOI

2019

Pharmacokinetics and oral bioavailability studies of three saikogenins in rats using a validated UFLC-MS/MS method

Jingjing Liu, Yunwen Xue, Jianbo Sun, Rui‐Jia Fu, Siqi Ren, Zunjian Zhang, Rui Song

Journal of Chromatography B

DOI

2018

酚类化合物经UGTs代谢和药物相互作用的研究进展

胡光南，张尊建，宋瑞

《药学进展》

2018

Intestinal metabolism of Polygonum cuspidatum in vitro and in vivo

Jinfeng Fu, Songyan Wu, Min Wang, Yuan Tian, Zunjian Zhang, Rui Song

Biomedical Chromatography

DOI

2017

新加坡药学本科教育模式简介及思考

宋瑞，柳文媛，王欣然

《药学教育》

2017

Use of liquid chromatography hybrid triple‐quadrupole mass spectrometry for the detection of emodin metabolites in rat bile and urine

Songyan Wu, Yaqing Zhang, Zunjian Zhang, Rui Song

Biomedical Chromatography

DOI

2016

In vitro metabolism study of saikosaponin d and its derivatives in rat liver microsomes

Pei Yu, Hong-Cong Qiu, Min Wang, Yuan Tian, Zunjian Zhang, Rui Song

Xenobiotica

DOI

2016

Influence of wine-processing on the pharmacokinetics of anthraquinone aglycones and glycosides from rhubarb in hyperlipidemic hamsters

Min Wang, Guangnan Hu, Yuan Tian, Zunjian Zhang, Rui Song

RSC Advances

DOI

2015

Targeted quantitative analysis of anthraquinone derivatives by high-performance liquid chromatography coupled with tandem mass spectrometry to discriminate between crude and processed rhubarb samples

Min Wang, Yuan Tian, Mengying Lv, Fengguo Xu, Zunjian Zhang, Rui Song

Analytical Methods

DOI

2014

中药分析实验教学改革

王磊，严方，汪丽霞，宋瑞，狄斌

《药学教育》

2014

Discrimination of crude and processed rhubarb products using a chemometric approach based on ultra fast liquid chromatography with ion trap/time‐of‐flight mass spectrometry

Min Wang, Jinfeng Fu, Huimin Guo, Yuan Tian, Fengguo Xu, Rui Song, Zunjian Zhang

Journal of Separation Science

DOI

2014

Effect of wine processing and acute blood stasis on the serum pharmacochemistry of rhubarb: A possible explanation for processing mechanism

Min Wang, Jinfeng Fu, Mengying Lv, Yuan Tian, Fengguo Xu, Rui Song, Zunjian Zhang

Journal of Separation Science

DOI

2014

Metabolism of Brucine: The Important Metabolic Pathways of Dihydroindole-Type Alkaloid for Excretion in Rats

Ji-Xin Tian, Min Wang, Lei Xu, Yuan Tian, Rui Song, Fengguo Xu, Zunjian Zhang

Bioanalysis

DOI

2013

以实时求证为特色的药物分析研究性教学模式

宋瑞，杭太俊，张尊建

《药学教育》

DOI

2012

中药分析课程教学改革

严方，狄斌，宋瑞，杭太俊

《药学教育》

2012

柴胡醋制前后柴胡皂苷a、b2、c、d的LC-MS/MS法测定及比较

许磊，田稷馨，宋瑞，刘国强，田媛，张尊建

《中国药科大学学报》

2011

Quantitative Determination of Nitrendipine in Human Plasma Using High-performance Liquid Chromatography-Mass Spectrometry

Ying Liu, Fengguo Xu, Zunjian Zhang, Rui Song, Yuan Tian, Yun Chen

Arzneimittelforschung

DOI

2011

Analysis of saikosaponins in rat plasma by anionic adducts‐based liquid chromatography tandem mass spectrometry method

Lei Xu, Rui Song, Ji‐Xin Tian, Yuan Tian, Guoqiang Liu, Zunjian Zhang

Biomedical Chromatography

DOI

2010

大鼠灌服枳实提取液后体内黄酮类代谢产物的LC-MS/MS分析

李哲，宋瑞，许风国，许磊，田媛，张尊建

《中国药科大学学报》

2010

In vivo metabolism study of rhubarb decoction in rat using high-performance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples

Rui Song, Lei Xu, Fengguo Xu, Zhe Li, Haijuan Dong, Yuan Tian, Zunjian Zhang

Journal of Chromatography A

DOI

2010

Metabolic analysis of rhubarb extract by rat intestinal bacteria using liquid chromatography–tandem mass spectrometry

Rui Song, Lei Xu, Fengguo Xu, Haijuan Dong, Yuan Tian, Zunjian Zhang

Biomedical Chromatography

DOI

2010

HPLC/DAD Comparison of Sixteen Bioactive Components between Da-Cheng-Qi Decoction and its Parent Herbal Medicines

Fengguo Xu, Ying Liu, Rui Song, Haijuan Dong, Zunjian Zhang

Natural Product Communications

DOI

2010

Pharmacokinetic Comparison in Rats of Six Bioactive Compounds between Da-Cheng-Qi Decoction and its Parent Herbal Medicines

Fengguo Xu, Ying Liu, Haijuan Dong, Rui Song, Zunjian Zhang

Natural Product Communications

DOI

2010

Constituents of Da-Cheng-Qi Decoction and its Parent Herbal Medicines Determined by LC-MS/MS

Fengguo Xu, Ying Liu, Rui Song, Haijuan Dong, Zunjian Zhang

Natural Product Communications

DOI

2010

Determination of Gallic Acid in Rat Plasma by LC-MS-MS

Rui Song, Lei Xu, Zunjian Zhang, Yuan Tian, Fengguo Xu, Haijuan Dong

Chromatographia

DOI

2009

Profiling the metabolic differences of anthraquinone derivatives using liquid chromatography/tandem mass spectrometry with data‐dependent acquisition

Rui Song, Hui Yen Lin, Zunjian Zhang, Zhe Li, Lei Xu, Haijuan Dong, Yuan Tian

Rapid Communications in Mass Spectrometry

DOI

2008

LC-MS/MS法研究大承气汤与其君药大黄物质基础间的相关性

许风国，刘颖，宋瑞，董海娟，田媛，张尊建

《中国药科大学学报》

2008

Structural elucidation of in vitro metabolites of emodin by liquid chromatography–tandem mass spectrometry

Rui Song, Fengguo Xu, Zunjian Zhang, Ying Liu, Haijuan Dong, Yuan Tian

Biomedical Chromatography

DOI

2008

Simultaneous determination of naringenin and hesperetin in rats after oral administration of Da‐Cheng‐Qi decoction by high‐performance liquid chromatography–tandem mass spectrometry

Ying Liu, Fengguo Xu, Zunjian Zhang, Rui Song, Yuan Tian

Biomedical Chromatography

DOI

2008

Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction

Fengguo Xu, Ying Liu, Zunjian Zhang, Rui Song, Haijuan Dong, Yuan Tian

Journal of Pharmaceutical and Biomedical Analysis

DOI

2007

Simultaneous SPE-LC Determination of Three Flavonoid Glycosides of Naringin, Neohesperidin and Hesperidin in Da-Cheng-Qi Decoction

Fengguo Xu, Ying Liu, Zunjian Zhang, Rui Song, Cheng Yong Yang, Yuan Tian

Chromatographia

DOI

2006

非负矩阵因子分解算法解析手性药物重叠峰的HPLC-DAD数据

蒋淑敏，宋瑞，高洪涛，胡育筑

《中国药科大学学报》

精选作品

期刊论文

集成靶向和拟靶向策略测定健康及溃疡性结肠炎小鼠体内四逆散原型成分及代谢物

溃疡性结肠炎小鼠结肠及免疫组织中四逆散药源性成分的LC-MS分析

“拔尖计划”2.0背景下药物质量分析与控制课程建设

非酒精性脂肪性肝病细胞模型中胆固醇代谢紊乱机制

Study on the effect of calibration standards prepared with different matrix on the accuracy of bile acid quantification using LC-MS/MS

柴胡皂苷d的体内外肠道吸收机制研究

药源性糖尿病发病机制的研究进展

Saikosaponins and the deglycosylated metabolites exert liver meridian guiding effect through PXR/CYP3A4 inhibition

Corrigendum to “Pharmacokinetics and oral bioavailability studies of three saikogenins in rats using a validated UFLC-MS/MS method” [J. Chromatogr. B 1124 (2019) 265–272]

Pharmacokinetics and oral bioavailability studies of three saikogenins in rats using a validated UFLC-MS/MS method

酚类化合物经UGTs代谢和药物相互作用的研究进展

Intestinal metabolism of Polygonum cuspidatum in vitro and in vivo

新加坡药学本科教育模式简介及思考

Use of liquid chromatography hybrid triple‐quadrupole mass spectrometry for the detection of emodin metabolites in rat bile and urine

In vitro metabolism study of saikosaponin d and its derivatives in rat liver microsomes

Influence of wine-processing on the pharmacokinetics of anthraquinone aglycones and glycosides from rhubarb in hyperlipidemic hamsters

Targeted quantitative analysis of anthraquinone derivatives by high-performance liquid chromatography coupled with tandem mass spectrometry to discriminate between crude and processed rhubarb samples

中药分析实验教学改革

Discrimination of crude and processed rhubarb products using a chemometric approach based on ultra fast liquid chromatography with ion trap/time‐of‐flight mass spectrometry

Effect of wine processing and acute blood stasis on the serum pharmacochemistry of rhubarb: A possible explanation for processing mechanism

Metabolism of Brucine: The Important Metabolic Pathways of Dihydroindole-Type Alkaloid for Excretion in Rats

以实时求证为特色的药物分析研究性教学模式

中药分析课程教学改革

柴胡醋制前后柴胡皂苷a、b2、c、d的LC-MS/MS法测定及比较

Quantitative Determination of Nitrendipine in Human Plasma Using High-performance Liquid Chromatography-Mass Spectrometry

Analysis of saikosaponins in rat plasma by anionic adducts‐based liquid chromatography tandem mass spectrometry method

大鼠灌服枳实提取液后体内黄酮类代谢产物的LC-MS/MS分析

In vivo metabolism study of rhubarb decoction in rat using high-performance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples

Metabolic analysis of rhubarb extract by rat intestinal bacteria using liquid chromatography–tandem mass spectrometry

HPLC/DAD Comparison of Sixteen Bioactive Components between Da-Cheng-Qi Decoction and its Parent Herbal Medicines

Pharmacokinetic Comparison in Rats of Six Bioactive Compounds between Da-Cheng-Qi Decoction and its Parent Herbal Medicines

Constituents of Da-Cheng-Qi Decoction and its Parent Herbal Medicines Determined by LC-MS/MS

Determination of Gallic Acid in Rat Plasma by LC-MS-MS

Profiling the metabolic differences of anthraquinone derivatives using liquid chromatography/tandem mass spectrometry with data‐dependent acquisition

LC-MS/MS法研究大承气汤与其君药大黄物质基础间的相关性

Structural elucidation of in vitro metabolites of emodin by liquid chromatography–tandem mass spectrometry

Simultaneous determination of naringenin and hesperetin in rats after oral administration of Da‐Cheng‐Qi decoction by high‐performance liquid chromatography–tandem mass spectrometry

Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction

Simultaneous SPE-LC Determination of Three Flavonoid Glycosides of Naringin, Neohesperidin and Hesperidin in Da-Cheng-Qi Decoction

非负矩阵因子分解算法解析手性药物重叠峰的HPLC-DAD数据

预印本

In-Depth Practice and New Insights in Method Validation for the Absolute Quantification of Bile Acids Using Liquid Chromatography-Tandem Mass Spectrometry