翁祖铨｜福州大学｜学者主页

2026

Synergistic Wound Healing Enhancement by Extracellular Vesicles From Engineered Macrophages and Fibroblasts

Ping Liang, Jialin Ye, Kaiyang Lin, Qinghua Luo, Haisu Zheng, Yuyao Hu, Minglang Zou, Yanting Huang, Sifang Wu, Qi Sun, Yansong Guo, Zuquan Weng

Journal of Biomedical Materials Research Part A

DOI

2026

Gecko tail regeneration-inspired composite hydrogel scaffolds with “socket-plug” architecture for dynamically programmed repair of infected bone defects

Minglang Zou, Y F Tang, Yongming Wang, Ling Mo, Menghuan Wang, Qing He, Zhenjin Xu, Liu Su, Pengfei Wang, Fang Luo, Da Huang, Jiewei Luo, Zhenyu Lin, Zuquan Weng

Chemical Engineering Journal

DOI

2026

Proximal-distal coordination engineering of iron single-atom nanozyme for synergistic multi-enzymatic-photothermal control of antibiotic-resistant bacteria

Yunsen Wang, Zhichao Yu, Xiuhui Liang, Zhilan Bi, Minglang Zou, Shuo Tian, Da Huang, Zuquan Weng, Dianping Tang, Jinfeng Kong

Journal of Hazardous Materials

DOI

2026

A CRISPR/Cas12a−MXene Nanozyme Platform for Universal Detection of Trace DNA

Sufang Liu, Yuanlong Hu, Miao Zheng, F Zhang, Zhichao Yu, Qi Sun, Dianping Tang, Zuquan Weng, Zaisheng Ye

ACS Sensors

DOI

2026

A Controllable and Separable Nanozyme‐Based Platform for Enhanced Signal‐Off Colorimetric Biosensing

Minyang Su, Haiwei Hou, Zhiling Qu, Ruiping Wu, Yazhong Bu, Zuquan Weng, Baoji Du

Advanced Sustainable Systems

DOI

2026

Tuning d-f hybridization to mimic haloperoxidase for microneedle-assisted targeted therapy of drug-resistant infections

Zhichao Yu, Fengrui Gao, Minglang Zou, Man Xu, Sufang Liu, Da Huang, Zuquan Weng, Yongyi Zeng, Dianping Tang, Xiaolong Liu

Chemical Engineering Journal

DOI

2026

Machine learning for identifying risk factors of nosocomial infection in cancer patients with immune checkpoint inhibitor-related pneumonia

Jianzhong Xie, Zhuo Zhao, Cuiyun Zhou, Junxiang Wang, Xiufang Lin, Lingyu Lai, Jinchan Yao, Haiyan Lin, Zuquan Weng

BMC Infectious Diseases

DOI

2026

CRISPR-engineered zebrafish expression system for human type III collagen: Therapeutic efficacy in wound healing

Qinghua Luo, Yanting Huang, Houbing Zheng, Wenya Ke, Haisu Zheng, Qi Sun, M Wang, Zuquan Weng

International Journal of Biological Macromolecules

DOI

2025

Acid-Labile Liver-Targeted Unimolecular Micelles Based on Hyperbranched Polyprodrug Amphiphiles for Targeted Therapy of Hepatic Fibrosis

Jiahao Du, Jinyi Mu, Minglang Zou, Yi Ping Tang, Pengfei Wang, Zuquan Weng, JieWei Luo, Da Huang

Biomacromolecules

DOI

2025

Leak-free encapsulation of EGF-expressing yeast in a hyaluronic acid-based hydrogel for diabetes wound healing

Xiaofang Sun, Jingjing Shu, Jianan He, Jingwen Cai, Xuefeng Xu, Yan Fen, Fang Yuan Luo, Da Huang, Yuanzi Wu, Zuquan Weng

International Journal of Biological Macromolecules

DOI

2025

BPEI-Stabilized Photocatalytic Au/Titania Nanoclusters with Enhanced Antimicrobial Activity for Wound Healing Applications

Junheng Ke, Linhai Jiang, Qi Sun, Sifang Wu, Houbing Zheng, Jialin Ye, Haisu Zheng, Yijun Zhong, Da Huang, Yuanzi Wu, Biao Wang, Zuquan Weng

International Journal of Nanomedicine

DOI

2025

Rapid and non-destructive detection of formaldehyde adulteration in shrimp based on deep learning-assisted portable Raman spectroscopy

Chencheng Wei, Jiheng Zhang, Gaozheng Li, Yi Zhong, Zhaoting Ye, Handong Wang, Kezhi Li, Yuanzi Wu, Yuezhong Wu, Heng Luo, Qi Sun, Zuquan Weng

Food Chemistry

DOI

2025

A colorimetric immunoassay for visual detection of zearalenone based on the Fenton reaction on gold nanorods

Yuanlong Hu, Jiamin Chen, Sifang Wu, Yi Zhong, Jialin Ye, Lingqing Ye, Yuanzi Wu, Da Huang, Qi Sun, Fang Zhang, Zuquan Weng

Journal of Food Measurement & Characterization

DOI

2025

One-pot synthesis of highly stable CsPbBr₃@C6H7NO3S composite and its application in nitrite fluorescent sensing

Yongzhen Qiu, Yexin Zu, Yating Zhang, Yue Lin, Fang Luo, Zuquan Weng, Cuiying Lin, Jian Wang, Bin Qiu, Zhenyu Lin

Food Chemistry

DOI

2025

Advanced dual-signal point-of-care testing platform for sensitive T-2 toxin detection: Integrating copper-based conductive MOF with target-responsive DNA hydrogel

Jiarong Lin, Jiarong Lin, Ye Deng, Yue Lin, Yue Lin, Fang Luo, Zuquan Weng, Jian Wang, Zhenyu Lin, Cuiying Lin, Bin Qiu, Zhenyu Lin

Sensors and Actuators B Chemical

DOI

2025

Microbe-imprinted polymers for rapid drug-resistant bacteria recognition

Yuanzi Wu, Kaiqiang Zhou, Wenhui Li, Minghui Huan, Zhichao Yu, Fen Yan, Huixiao Hong, Dianping Tang, Yansong Guo, Zuquan Weng

Chemical Engineering Journal

DOI

2025

ROS-Responsive Cationic Polymers with Intrinsic Anti-Inflammatory Activity for Intracellular Protein Delivery

Yong-ming Wang, Yangcan Ming, Zhichao Yu, Zhenjin Xu, Minglang Zou, Cuiping Chen, Fang Luo, Da Huang, Na Wang, Zhenyu Lin, Zuquan Weng

Biomacromolecules

DOI

2025

Ultrasensitive Homogeneous Electrochemiluminescence Biosensor for N-Nitrosodimethylamine Detection Based on Vertically-Ordered Mesoporous Silica Film-Modified Electrode and CRISPR/Cas12a-Driven HRCA with Triple Signal Amplification

Zhenjie Zheng, Zhuozhen Qian, Da Huang, Zuquan Weng, Jian Wang, Cuiying Lin, Bin Qiu, Zhenyu Lin, Fang Luo

Analytical Chemistry

DOI

2025

Intelligent larval zebrafish phenotype recognition via attention mechanism for high-throughput screening

Baihua Wang, Qi Sun, Yujia Liu, Jiheng Zhang, Gaozheng Li, Sifang Wu, Houbing Zheng, Jialin Ye, Meihua Zhou, Haisu Zheng, Yongqiang Yu, Yi Zhong, Yuanzi Wu, Da Huang, Biao Wang, Zuquan Weng

Computers in Biology and Medicine

DOI

2025

Dual-signal point-of-care testing method for T-2 toxin utilizing target-responsive DNA hydrogel and starch iodide paper

Ye Deng, Jiarong Lin, Jingxuan Wang, Yue Lin, Fang Luo, Zuquan Weng, Jian Wang, Cuiying Lin, Bin Qiu, Zhenyu Lin

Microchemical Journal

DOI

2025

Facile Fabrication of Injectable Multifunctional Hydrogels Based on Gallium‐Polyphenol Networks with Superior Antibacterial Activity for Promoting Infected Wound Healing

Minglang Zou, Cuiping Chen, Ming-Da Wang, Lei Chen, Yongming Wang, Fang Luo, Da Huang, Meishui Wang, Houbing Zheng, Biao Wang, Zhenyu Lin, Zuquan Weng

Advanced Healthcare Materials

DOI

2024

基于小沟凹槽探针特异性检测23种人乳头瘤病毒分型的研究

黄妍婷，刘继来，高廷芳，许万里，柯文雅，何小镇，翁祖铨

《疾病监测》

2024

High-content imaging and deep learning-driven detection of infectious bacteria in wounds

Ziyi Zhang, Lanmei Gao, Houbing Zheng, Yi Zhong, Gaozheng Li, Zhaoting Ye, Qi Sun, Biao Wang, Zuquan Weng

Bioprocess and Biosystems Engineering

DOI

2024

Tailored Metal–Organic Framework‐Based Nanozymes for Enhanced Enzyme‐Like Catalysis

Zhichao Yu, Zhenjin Xu, Ruijin Zeng, Man Xu, Minglang Zou, Da Huang, Zuquan Weng, Dianping Tang

Angewandte Chemie

DOI

2024

D‐Band‐Center‐Engineered Platinum‐Based Nanozyme for Personalized Pharmacovigilance

Zhichao Yu, Zhenjin Xu, Ruijin Zeng, Man Xu, Haisu Zheng, Da Huang, Zuquan Weng, Dianping Tang

Angewandte Chemie

DOI

2024

Learning motif-based graphs for drug–drug interaction prediction via local–global self-attention

Yi Zhong, Gaozheng Li, Yang Ji, Houbing Zheng, Yongqiang Yu, Jiheng Zhang, Heng Luo, Biao Wang, Zuquan Weng

Nature Machine Intelligence

DOI

2024

Aluminium-copper-mesoporous silica molecular sieve-enabled dual-signal point-of-care aptasensor with integrated temperature and multicolor readout

Zhenjie Zheng, Linxiu Zhan, Liang Wang, Ye Deng, Yue Lin, Yue Lin, Fang Luo, Zuquan Weng, Cuiying Lin, Zhenyu Lin, Bin Qiu, Zhenyu Lin

Sensors and Actuators B Chemical

DOI

2024

Colon-targeted hydroxyethyl starch-curcumin microspheres with high loading capacity ameliorate ulcerative colitis via alleviating oxidative stress, regulating inflammation, and modulating gut microbiota

Da Huang, Yongming Wang, Chenlan Xu, Minglang Zou, Yangcan Ming, Fang Luo, Zhenjin Xu, Ying Miao, Na Wang, Zhenyu Lin, Zuquan Weng

International Journal of Biological Macromolecules

DOI

2024

Photoelectrochemical Sensor for H 2 S Based on a Lead-Free Perovskite/Metal–Organic Framework Composite

Mengfan Mao, Yexin Zu, Yating Zhang, Yongzhen Qiu, Yue Lin, Fang Luo, Zuquan Weng, Cuiying Lin, Bin Qiu, Zhenyu Lin

Analytical Chemistry

DOI

2024

Novel antimicrobial peptides against Cutibacterium acnes designed by deep learning

Qichang Dong, Shaohua Wang, Ying Miao, Heng Luo, Zuquan Weng, Lun Yu

Scientific Reports

DOI

2024

Injectable Hydrogels with Integrated Ph Probes and Ultrasound‐Responsive Microcapsules as Smart Wound Dressings for Visual Monitoring and On‐Demand Treatment of Chronic Wounds

Da Huang, Jiahao Du, Fang Luo, Gang He, Minglang Zou, Yongming Wang, Zhenyu Lin, Decheng Wu, Zuquan Weng

Advanced Healthcare Materials

DOI

2023

自噬抑制剂通过氧化应激诱导人头皮毛乳头细胞早衰进程

万梅，钟意，翁祖铨，吴亚光，宋潇，杨希川

《中国皮肤性病学杂志》

2023

Hydroxypropyl-beta-Cyclodextrin embedded resveratrol regulates gut microbiota to prevent NAFLD via activating AMPK signaling pathway

Wen-Hsing Ke, Juan Huang, Yi Zhong, Yuhong Shi, Fen Yan, Da Huang, Yuan-Zi Wu, Hou-Bing Zheng, Zu-Quan Weng

Food Bioscience

DOI

2023

Fluorescent biosensor based on MB-APT combined with Pt NPs for the detection of infectious bacteria in mouse and human wounds

Lanmei Gao, Hou-Bing Zheng, Yuanlong Hu, Yi Zhong, Linhai Jiang, Yuan-Zi Wu, Fen Yan, Da Huang, Jianhua Li, Fang Zhang, Zhenyu Lin, Mei-Shui Wang, Zu-Quan Weng

Sensors and actuators. B, Chemical

DOI

2023

Oxygen-induced dual-signal point-of-care testing aptasensor for aflatoxin B1 detection using platinum nanoparticle catalysis in visual fluorometry and gravimetry.

Fang Luo, Linxiu Zhan, Ye Deng, Kun Qiao, Nan Pan, Zu-Quan Weng, Cui-Ying Lin, Bin Qiu, Zhenyu Lin

Analytica Chimica Acta

DOI

2023

Recent Advances in Polymer-Based Biosensors for Food Safety Detection

Binhui Wang, Da Huang, Zu-Quan Weng

Polymers

DOI

2023

Unimolecular Cascaded Multienzyme Conjugates Modulate the Microenvironment of Diabetic Wound to Promote Healing

Yuanzi Wu, Yanwei Lyu, Ling Li, Kaiqiang Zhou, Jingwen Cai, Xuwei Wang, Huiru Wang, Yan Fen, Zuquan Weng

Biomacromolecules

DOI

2023

Colon‐Targeted Oral Delivery of Hydroxyethyl Starch–Curcumin Microcapsules Loaded with Multiple Drugs Alleviates DSS‐Induced Ulcerative Colitis in Mice

Da Huang, Da Huang, Minglang Zou, Chenlan Xu, Yongming Wang, Zhenjin Xu, Wancong Zhang, Wancong Zhang, Shijie Tang, Shijie Tang, Zuquan Weng

Macromolecular Bioscience

DOI

2023

A novel electrochemiluminescence aptasensor using Ti3C2@AuNRs-Ru for ultra-sensitive detection of T-2 toxin

Junyi Zhang, Ye Deng, Lifen Chen, Fang Luo, Zuquan Weng, Cuiying Lin, Cuiying Lin, Bin Qiu, Longhua Guo, Zhenyu Lin

Electrochimica Acta

DOI

2023

Signal-on photoelectrochemical sensing by highly stable perovskite nanocrystals based on in situ formation of heterojunction

Yating Zhang, Xiaoyu Zheng, Siqi Chen, Yongzhen Qiu, Fang Luo, Zuquan Weng, Bin Qiu, Jian Shou, Zhenyu Lin

Sensors and Actuators B Chemical

DOI

2023

Multiplex detection methods for mycotoxins in agricultural products: A systematic review

Chencheng Wei, Handong Wang, Gaozheng Li, Jianhua Li, Fang Zhang, Yuezhong Wu, Zuquan Weng

Food Control

DOI

2023

MMBERT: a unified framework for biomedical named entity recognition

Lei Fu, Zuquan Weng, Jiheng Zhang, Haihe Xie, Yiqing Cao

Medical & Biological Engineering & Computing

DOI

2023

Deep Learning-Based System for Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images

Xiaoming Chen, Ying Xue, Xiaoyan Wu, Yi Zhong, Huiying Rao, Heng Luo, Zuquan Weng

Translational Vision Science & Technology

DOI

2023

Anti-inflammatory unimolecular micelles of redox-responsive hyperbranched polycurcumin amphiphiles with enhanced anti-inflammatory efficacy in vitro and in vivo

Da Huang, Qiang Tang, Minglang Zou, Yongming Wang, Fang Luo, Jinyi Mu, Yuanzi Wu, Zuquan Weng, Zhenyu Lin

Polymer Chemistry

DOI

2022

Colon-targeted oral nanoparticles based on ROS-scavenging hydroxyethyl starch-curcumin conjugates for efficient inflammatory bowel disease therapy.

Chenlan Xu, Shuting Chen, Cuiping Chen, Yangcan Ming, Jiahao Du, Jinyi Mu, Fang Luo, Da Huang, Na Wang, Zhenyu Lin, Zu-Quan Weng

International journal of pharmaceutics

DOI

2022

Study on the Characteristics of Small-Molecule Kinase Inhibitors-Related Drug-Induced Liver Injury

Hui-Feng Dong, Jia You, Yu Zhao, Danhua Zheng, Yi Zhong, Gaozhen Li, Zu-Quan Weng, Heng Luo, Shan Jiang

Frontiers in Pharmacology

DOI

2022

Statistical Analysis and Machine Learning Prediction of Disease Outcomes for COVID-19 and Pneumonia Patients

Yu Zhao, Ru-Sen Zhang, Yi Zhong, Jing-Jing Wang, Zu-Quan Weng, Heng Luo, Cunrong Chen

Frontiers in Cellular and Infection Microbiology

DOI

2022

Photothermal sensor based on water-soluble CsPbBr3@sulfobutylether-β-cyclodextrins nanocomposite using a thermometer as readout

Shi-Qing Li, Yating Zhang, Yexing Zu, Yi-Ting Chen, Fang Luo, Da Huang, Zu-Quan Weng, Bin Qiu, Zhenyu Lin

Sensors and actuators. B, Chemical

DOI

2022

Deep learning detection of shrimp freshness via smartphone pictures

Yuehan Zhang, Chencheng Wei, Yi Zhong, Han-Dong Wang, Heng Luo, Zu-Quan Weng

Journal of Food Measurement & Characterization

DOI

2022

Morphological characteristics of zebrafish's yolk sac for malformation based on orthogonal‐polarization‐gating optical coherence tomography

Ke Li, Yi Wang, Yujia Liu, Wangbiao Li, Zuquan Weng, Hui Li, Youwu He, Zhifang Li

Journal of Biophotonics

DOI

2021

Association Between the Characteristics of Small-molecule Kinase Inhibitors and Drug-induced Liver Injury: A Scoping Study (Preprint)

Hui-Feng Dong, Jia You, Yu Zhao, Da-dong Zheng, Yi Zhong, Zu-Quan Weng, Heng Luo, Sha-sha Jiang

DOI

2021

A machine learning predictive model of in-hospital mortality in patients with sepsis complicated by anemia: a retrospective study based on the MIMIC-III database

Xiao-Bin Liu, Yu Zhao, Yi-Yang Qin, Dan Wang, Xiaoxin Yin, Ren-Qi Yao, Qi-Min Ma, Yu-Song Wang, Shihui Zhu, Shao-Lin Ma, Zu-Quan Weng, F. Zhu

DOI

2021

Hydroxyethyl Starch Curcumin Enhances Antiproliferative Effect of Curcumin Against HepG2 Cells via Apoptosis and Autophagy Induction

Linhai Jiang, Xiaoliang Cai, Sheng Li, Ying-Ke Miao, Xiaoyu Yang, Manbian Lin, Liang Chen, Xiao-Zhen He, Zu-Quan Weng

Frontiers in Pharmacology

DOI

2021

Partially Hydrolyzed Guar Gum Modulates Gut Microbiota, Regulates the Levels of Neurotransmitters and Prevents CUMS-Induced Depressive-like Behavior in Mice.

Yanqiu Chen, Mei Wan, Yi Zhong, Tingfang Gao, Yuehan Zhang, Fen Yan, Da Huang, Yuan-Zi Wu, Zu-Quan Weng

Molecular Nutrition & Food Research

DOI

2021

Protective effects of (-)-epigallocatechin gallate and curcumin against acrylamide toxicity

Shanshan Wang, Hufei Wang, Yanqiu Chen, Ji-Lai Liu, Xiao-Zhen He, Da Huang, Yuan-Zi Wu, Yong-Hai Chen, Zu-Quan Weng

Toxicological & Environmental Chemistry

DOI

2021

Biocompatible perovskite quantum dots with superior water resistance enable long-term monitoring of the H2S level in vivo.

Fang Luo, Shi-Qing Li, Li-Yun Cui, Yexing Zu, Yi-Ting Chen, Da Huang, Zu-Quan Weng, Zhen Lin

Nanoscale

DOI

2021

Preliminary Study on Hepatoprotective Effect and Mechanism of (-)-Epigallocatechin-3-gallate against Acetaminophen-induced Liver Injury in Rats

Yong-Xu Lin, Juan Huang, Tingfang Gao, Yuan-Zi Wu, Da Huang, Fen Yan, Zu-Quan Weng

Iranian journal of pharmaceutical research

DOI

2021

Application of optical coherence tomography for morphological change of Staphylococcus during reproduction

珂李，Dezi Li，Lanmei Gao，Zuquan Weng，Mingjie Zheng，Youwu He，Zhifang Li

DOI

2020

Machine-Learning Prediction of Oral Drug-Induced Liver Injury (DILI) via Multiple Features and Endpoints

Xiao-Bin Liu, Danhua Zheng, Yi Zhong, Z. Xia, Heng Luo, Zu-Quan Weng

BioMed Research International

DOI

2020

Aldehyde dehydrogenase 2 deficiency significantly exacerbates tert‐butyl alcohol‐induced toxicity in mice

Li-Ping Lin, M. Suda, Chenlan Xu, Yuehan Zhang, Y. Yanagiba, J. Nie, T. Nakajima, Zu-Quan Weng, Rui-Sheng Wang

Journal of Applied Toxicology

DOI

2020

Superior antibacterial activity of sulfur-doped g-C3N4 nanosheets dispersed by Tetrastigma hemsleyanum Diels & Gilg's polysaccharides-3 solution.

Xiao Chen, Mingfeng Weng, Maojin Lan, Zu-Quan Weng, Jian Wang, Long-Hua Guo, Zhenyu Lin, Bin Qiu

International Journal of Biological Macromolecules

DOI

2020

Nano-micelles based on hydroxyethyl starch-curcumin conjugates for improved stability, antioxidant and anticancer activity of curcumin.

Shuting Chen, Jie Wu, Q. Tang, Chenlan Xu, Yan Huang, Da Huang, Fang Luo, Yuan-Zi Wu, Fen Yan, Zu-Quan Weng, Shao-Yun Wang

Carbohydrate Polymers

DOI

2019

Microcapsule-embedded hydrogel patches for ultrasound responsive and enhanced transdermal delivery of diclofenac sodium.

Da Huang, Mi Sun, Yazhong Bu, Fang Luo, Cui-Ying Lin, Zhenyu Lin, Zu-Quan Weng, Fei Yang, Decheng Wu

Journal of materials chemistry. B

DOI

2019

A fluorescent biosensor based on catalytic activity of platinum nanoparticles for freshness evaluation of aquatic products.

Jiamin Chen, Yi Lu, Fen Yan, Yuan-Zi Wu, Da Huang, Zu-Quan Weng

Food Chemistry

DOI

2019

Polyphenol extract from superheated steam processed tea waste attenuates the oxidative damage in vivo and in vitro.

Tingfang Gao, Yuhong Shi, Ying Xue, Fen Yan, Da Huang, Yuan-Zi Wu, Zu-Quan Weng

Journal of food biochemistry

DOI

2019

Cytocompatible Modification of Thermoresponsive Polymers on Living Cells for Membrane Proteomic Isolation and Analysis.

Yuan-Zi Wu, Shui-Gen Wu, Shanyun Ma, Fen Yan, Zu-Quan Weng

Analytical Chemistry

DOI

2018

Inhalation exposure to low levels of ethyl tertiary butyl ether: Its genetic effects were significantly modified by ALDH2 activity

Zu-Quan Weng, Yuhong Shi, M. Suda, Y. Yanagiba, T. Kawamoto, T. Nakajima, Rui-Sheng Wang

Environmental and Molecular Mutagenesis

DOI

2018

Highly sensitive electrochemical immunosensor for golgi protein 73 based on proximity ligation assay and enzyme-powered recycling amplification.

Ying Zhang, Xiaocui Huang, Fang Luo, Yun Lei, Li Chen, Zu-Quan Weng, Long-Hua Guo, Zhenyu Lin

Analytica Chimica Acta

DOI

2018

Acute inhalation co‐exposure to 1,2‐dichloropropane and dichloromethane cause liver damage by inhibiting mitochondrial respiration and defense ability in mice

Hufei Wang, Jiamin Chen, M. Suda, Y. Yanagiba, Zu-Quan Weng, Rui-Sheng Wang

Journal of Applied Toxicology

DOI

2017

An electrochemiluminescence biosensor for Kras mutations based on locked nucleic acid functionalized DNA walkers and hyperbranched rolling circle amplification.

Ying Zhang, Lixu Wang, Fang Luo, Bin Qiu, Long-Hua Guo, Zu-Quan Weng, Zhenyu Lin, Guo-nan Chen

Chemical Communications

DOI

2017

Charge-reversible and pH-responsive biodegradable micelles and vesicles from linear-dendritic supramolecular amphiphiles for anticancer drug delivery

Da Huang, Yaqiang Wang, Fei Yang, Hong Shen, Zu-Quan Weng, Decheng Wu

DOI

2016

Significant association between decreased ALDH2 activity and increased sensitivity to genotoxic effects in workers occupationally exposed to styrene

Zu-Quan Weng, M. Suda, Mei Wan, Xing Zhang, Dongzhu Guan, Pei-Qing Zhao, Yuxin Zheng, M. Miyagawa, Rui-Sheng Wang

OncoTarget

DOI

2015

A comprehensive study of the association between drug hepatotoxicity and daily dose, liver metabolism, and lipophilicity using 975 oral medications

Zu-Quan Weng, Kejian Wang, Haibo Li, Q. Shi

OncoTarget

DOI

2015

Regorafenib impairs mitochondrial functions, activates AMP-activated protein kinase, induces autophagy, and causes rat hepatocyte necrosis.

Zu-Quan Weng, Yong Luo, Xi Yang, J. Greenhaw, Haibo Li, Li-Ming Xie, W. Mattes, Q. Shi

Toxicology

DOI

2015

Systematic drug safety evaluation based on public genomic expression (Connectivity Map) data: myocardial and infectious adverse reactions as application cases.

Kejian Wang, Zu-Quan Weng, Li-Ya Sun, Jia-Zhi Sun, Shu-Feng Zhou, Lin He

Biochemical and Biophysical Research Communications - BBRC

DOI

2014

Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria.

Zu-Quan Weng, P. Zhou, W. Salminen, Xi Yang, A. Harrill, Zhijun Cao, W. Mattes, D. Mendrick, Q. Shi

Biochemical and Biophysical Research Communications - BBRC

DOI

2014

Assessment of the reproductive toxicity of inhalation exposure to ethyl tertiary butyl ether in male mice with normal, low active and inactive ALDH2

Zu-Quan Weng, K. Ohtani, M. Suda, Y. Yanagiba, T. Kawamoto, T. Nakajima, Rui-Sheng Wang

Archives of Toxicology

DOI

2014

Circulating extracellular vesicles as a potential source of new biomarkers of drug-induced liver injury.

Xi Yang, Zu-Quan Weng, D. Mendrick, Q. Shi

Toxicology Letters

DOI

2013

Cell‐free microRNAs as Biomarkers in Human Diseases

Xi Yang, W. Mattes, Q. Shi, Zu-Quan Weng, W. Salminen

DOI

2013

Subchronic exposure to ethyl tertiary butyl ether resulting in genetic damage in Aldh2 knockout mice.

Zu-Quan Weng, M. Suda, K. Ohtani, Nan Mei, T. Kawamoto, T. Nakajima, Rui-Sheng Wang

Toxicology

DOI

2012

Enhanced reproductive effects of exposure to ETBE in Aldh2 knockout mice

Rui-Sheng Wang, K. Ohtani, Zu-Quan Weng, Y. Yanagiba, M. Suda

DOI

2012

Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes.

Zu-Quan Weng, J. Greenhaw, W. Salminen, Q. Shi

Toxicology Letters

DOI

2011

Differential genotoxic effects of subchronic exposure to ethyl tertiary butyl ether in the livers of Aldh2 knockout and wild-type mice

Zu-Quan Weng, M. Suda, K. Ohtani, Nan Mei, T. Kawamoto, T. Nakajima, Rui-Sheng Wang

Archives of Toxicology

DOI

2011

Reproductive effects of exposure to ethyl tertiary butyl ether as modified by aging in male ALDH2 knockout mice

Rui-Sheng Wang, K. Ohtani, Zu-Quan Weng, M. Suda

DOI

2011

Aldh2 knockout mice were more sensitive to DNA damage in leukocytes due to ethyl tertiary butyl ether exposure.

Zu-Quan Weng, M. Suda, K. Ohtani, Nan Mei, T. Kawamoto, T. Nakajima, Rui-Sheng Wang

Industrial Health

DOI

2011

Genetic effect of exposure to ethyl tertiary butyl ether in mice leukocytes as modified by aging and ALDH2 genotypes

Zu-Quan Weng, M. Suda, K. Ohtani, Y. Yanagiba, Rui-Sheng Wang

DOI

2010

Difference in the genotoxicity of chronic inhalation exposure to ethyl tertiary butyl ether in sperm between ALDH2 wild-type and ALDH2 knockout mice

Zu-Quan Weng, M. Suda, K. Ohtani, Rui-Sheng Wang

DOI

2010

Effects of alcohol-drinking behaviour and ADH1B and ALDH2 polymorphisms on basal DNA damage in human mononuclear cells as determined by the comet assay.

Hua-Chun Weng, Zu-Quan Weng, Yu-Quan Lu, Kunio Nakayama, K. Morimoto

Mutation research

DOI

2010

P104-026Toxic effects of ethyl tertiary butyl ether exposure as modified by ALDH2 gene in mice

Rui-Sheng Wang, K. Ohtani, M. Suda, Zu-Quan Weng

DOI

2010

Toxicokinetics of ethyl tertiary butyl ether metabolites in blood and tissues in ALDH2 knockout and wild type mice

M. Suda, Zu-Quan Weng, K. Ohtani, Rui-Sheng Wang

DOI

2009

ヒト血液単核細胞の基本的DNA損傷に対する喫煙,XRCC1遺伝的多型,年齢の影響

Hua-Chun Weng, Zu-Quan Weng, Yu-Quan Lu, Kunio Nakayama, K. Morimoto

2009

Effects of cigarette smoking, XRCC1 genetic polymorphisms, and age on basal DNA damage in human blood mononuclear cells.

Hua-Chun Weng, Zu-Quan Weng, Yu-Quan Lu, Kunio Nakayama, K. Morimoto

Mutation research

DOI

2008

Effects of the XRCC1 gene‐environment interactions on DNA damage in healthy Japanese workers

Zu-Quan Weng, Yu-Quan Lu, Hua-Chun Weng, K. Morimoto

Environmental and Molecular Mutagenesis

DOI

2008

Differential DNA damage induced by H2O2 and bleomycin in subpopulations of human white blood cells.

Hua-Chun Weng, Yu-Quan Lu, Zu-Quan Weng, K. Morimoto

Mutation research

DOI

精选作品

期刊论文

Synergistic Wound Healing Enhancement by Extracellular Vesicles From Engineered Macrophages and Fibroblasts

Gecko tail regeneration-inspired composite hydrogel scaffolds with “socket-plug” architecture for dynamically programmed repair of infected bone defects

Proximal-distal coordination engineering of iron single-atom nanozyme for synergistic multi-enzymatic-photothermal control of antibiotic-resistant bacteria

A CRISPR/Cas12a−MXene Nanozyme Platform for Universal Detection of Trace DNA

A Controllable and Separable Nanozyme‐Based Platform for Enhanced Signal‐Off Colorimetric Biosensing

Tuning d-f hybridization to mimic haloperoxidase for microneedle-assisted targeted therapy of drug-resistant infections

Machine learning for identifying risk factors of nosocomial infection in cancer patients with immune checkpoint inhibitor-related pneumonia

CRISPR-engineered zebrafish expression system for human type III collagen: Therapeutic efficacy in wound healing

Acid-Labile Liver-Targeted Unimolecular Micelles Based on Hyperbranched Polyprodrug Amphiphiles for Targeted Therapy of Hepatic Fibrosis

Leak-free encapsulation of EGF-expressing yeast in a hyaluronic acid-based hydrogel for diabetes wound healing

BPEI-Stabilized Photocatalytic Au/Titania Nanoclusters with Enhanced Antimicrobial Activity for Wound Healing Applications

Rapid and non-destructive detection of formaldehyde adulteration in shrimp based on deep learning-assisted portable Raman spectroscopy

A colorimetric immunoassay for visual detection of zearalenone based on the Fenton reaction on gold nanorods

One-pot synthesis of highly stable CsPbBr₃@C6H7NO3S composite and its application in nitrite fluorescent sensing

Advanced dual-signal point-of-care testing platform for sensitive T-2 toxin detection: Integrating copper-based conductive MOF with target-responsive DNA hydrogel

Microbe-imprinted polymers for rapid drug-resistant bacteria recognition

ROS-Responsive Cationic Polymers with Intrinsic Anti-Inflammatory Activity for Intracellular Protein Delivery

Ultrasensitive Homogeneous Electrochemiluminescence Biosensor for N-Nitrosodimethylamine Detection Based on Vertically-Ordered Mesoporous Silica Film-Modified Electrode and CRISPR/Cas12a-Driven HRCA with Triple Signal Amplification

Intelligent larval zebrafish phenotype recognition via attention mechanism for high-throughput screening

Dual-signal point-of-care testing method for T-2 toxin utilizing target-responsive DNA hydrogel and starch iodide paper

Facile Fabrication of Injectable Multifunctional Hydrogels Based on Gallium‐Polyphenol Networks with Superior Antibacterial Activity for Promoting Infected Wound Healing

基于小沟凹槽探针特异性检测23种人乳头瘤病毒分型的研究

High-content imaging and deep learning-driven detection of infectious bacteria in wounds

Tailored Metal–Organic Framework‐Based Nanozymes for Enhanced Enzyme‐Like Catalysis

D‐Band‐Center‐Engineered Platinum‐Based Nanozyme for Personalized Pharmacovigilance

Learning motif-based graphs for drug–drug interaction prediction via local–global self-attention

Aluminium-copper-mesoporous silica molecular sieve-enabled dual-signal point-of-care aptasensor with integrated temperature and multicolor readout

Colon-targeted hydroxyethyl starch-curcumin microspheres with high loading capacity ameliorate ulcerative colitis via alleviating oxidative stress, regulating inflammation, and modulating gut microbiota

Photoelectrochemical Sensor for H 2 S Based on a Lead-Free Perovskite/Metal–Organic Framework Composite

Novel antimicrobial peptides against Cutibacterium acnes designed by deep learning

Injectable Hydrogels with Integrated Ph Probes and Ultrasound‐Responsive Microcapsules as Smart Wound Dressings for Visual Monitoring and On‐Demand Treatment of Chronic Wounds

自噬抑制剂通过氧化应激诱导人头皮毛乳头细胞早衰进程

Hydroxypropyl-beta-Cyclodextrin embedded resveratrol regulates gut microbiota to prevent NAFLD via activating AMPK signaling pathway

Fluorescent biosensor based on MB-APT combined with Pt NPs for the detection of infectious bacteria in mouse and human wounds

Oxygen-induced dual-signal point-of-care testing aptasensor for aflatoxin B1 detection using platinum nanoparticle catalysis in visual fluorometry and gravimetry.

Recent Advances in Polymer-Based Biosensors for Food Safety Detection

Unimolecular Cascaded Multienzyme Conjugates Modulate the Microenvironment of Diabetic Wound to Promote Healing

Colon‐Targeted Oral Delivery of Hydroxyethyl Starch–Curcumin Microcapsules Loaded with Multiple Drugs Alleviates DSS‐Induced Ulcerative Colitis in Mice

A novel electrochemiluminescence aptasensor using Ti3C2@AuNRs-Ru for ultra-sensitive detection of T-2 toxin

Signal-on photoelectrochemical sensing by highly stable perovskite nanocrystals based on in situ formation of heterojunction

Multiplex detection methods for mycotoxins in agricultural products: A systematic review

MMBERT: a unified framework for biomedical named entity recognition

Deep Learning-Based System for Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images

Anti-inflammatory unimolecular micelles of redox-responsive hyperbranched polycurcumin amphiphiles with enhanced anti-inflammatory efficacy in vitro and in vivo

Colon-targeted oral nanoparticles based on ROS-scavenging hydroxyethyl starch-curcumin conjugates for efficient inflammatory bowel disease therapy.

Study on the Characteristics of Small-Molecule Kinase Inhibitors-Related Drug-Induced Liver Injury

Statistical Analysis and Machine Learning Prediction of Disease Outcomes for COVID-19 and Pneumonia Patients

Photothermal sensor based on water-soluble CsPbBr3@sulfobutylether-β-cyclodextrins nanocomposite using a thermometer as readout

Deep learning detection of shrimp freshness via smartphone pictures

Morphological characteristics of zebrafish's yolk sac for malformation based on orthogonal‐polarization‐gating optical coherence tomography

Association Between the Characteristics of Small-molecule Kinase Inhibitors and Drug-induced Liver Injury: A Scoping Study (Preprint)

A machine learning predictive model of in-hospital mortality in patients with sepsis complicated by anemia: a retrospective study based on the MIMIC-III database

Hydroxyethyl Starch Curcumin Enhances Antiproliferative Effect of Curcumin Against HepG2 Cells via Apoptosis and Autophagy Induction

Partially Hydrolyzed Guar Gum Modulates Gut Microbiota, Regulates the Levels of Neurotransmitters and Prevents CUMS-Induced Depressive-like Behavior in Mice.

Protective effects of (-)-epigallocatechin gallate and curcumin against acrylamide toxicity

Biocompatible perovskite quantum dots with superior water resistance enable long-term monitoring of the H2S level in vivo.

Preliminary Study on Hepatoprotective Effect and Mechanism of (-)-Epigallocatechin-3-gallate against Acetaminophen-induced Liver Injury in Rats

Application of optical coherence tomography for morphological change of Staphylococcus during reproduction

Machine-Learning Prediction of Oral Drug-Induced Liver Injury (DILI) via Multiple Features and Endpoints

Aldehyde dehydrogenase 2 deficiency significantly exacerbates tert‐butyl alcohol‐induced toxicity in mice

Superior antibacterial activity of sulfur-doped g-C3N4 nanosheets dispersed by Tetrastigma hemsleyanum Diels & Gilg's polysaccharides-3 solution.

Nano-micelles based on hydroxyethyl starch-curcumin conjugates for improved stability, antioxidant and anticancer activity of curcumin.

Microcapsule-embedded hydrogel patches for ultrasound responsive and enhanced transdermal delivery of diclofenac sodium.

A fluorescent biosensor based on catalytic activity of platinum nanoparticles for freshness evaluation of aquatic products.

Polyphenol extract from superheated steam processed tea waste attenuates the oxidative damage in vivo and in vitro.

Cytocompatible Modification of Thermoresponsive Polymers on Living Cells for Membrane Proteomic Isolation and Analysis.

Inhalation exposure to low levels of ethyl tertiary butyl ether: Its genetic effects were significantly modified by ALDH2 activity

Highly sensitive electrochemical immunosensor for golgi protein 73 based on proximity ligation assay and enzyme-powered recycling amplification.

Acute inhalation co‐exposure to 1,2‐dichloropropane and dichloromethane cause liver damage by inhibiting mitochondrial respiration and defense ability in mice

An electrochemiluminescence biosensor for Kras mutations based on locked nucleic acid functionalized DNA walkers and hyperbranched rolling circle amplification.

Charge-reversible and pH-responsive biodegradable micelles and vesicles from linear-dendritic supramolecular amphiphiles for anticancer drug delivery

Significant association between decreased ALDH2 activity and increased sensitivity to genotoxic effects in workers occupationally exposed to styrene

A comprehensive study of the association between drug hepatotoxicity and daily dose, liver metabolism, and lipophilicity using 975 oral medications

Regorafenib impairs mitochondrial functions, activates AMP-activated protein kinase, induces autophagy, and causes rat hepatocyte necrosis.

Systematic drug safety evaluation based on public genomic expression (Connectivity Map) data: myocardial and infectious adverse reactions as application cases.

Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria.

Assessment of the reproductive toxicity of inhalation exposure to ethyl tertiary butyl ether in male mice with normal, low active and inactive ALDH2

Circulating extracellular vesicles as a potential source of new biomarkers of drug-induced liver injury.