百晓学者学者目录

车慧

教授，皖南医学院

精选作品

期刊论文

2026

基于TGF-β1/Smad信号通路探讨桑枝总生物碱对糖尿病心肌纤维化的影响

孔洒洒，王梦亭，孟涵，谢兆宇，徐涛，傅雪莲，车慧

《中医药学报》

2025

甜叶菊根多糖通过调控PI3K/AKT/NF-κB通路缓解肥胖相关炎症

鲍玉龙，柳春燕，车慧，吕秋月，周心月，邵太丽，王国栋

《天然产物研究与开发》

DOI

2025

金丝桃苷通过激活PKC/mitoKATP信号通路减轻大鼠心肌缺血再灌注损伤的作用研究

杨著，贺诗涵，王书凡，曹文，吕秋月，吴江平，车慧，王国栋，韩军

《中国中药杂志》

2025

健脾清化颗粒对胃食管反流病脾虚湿热证模型大鼠食管组织炎症及脂多糖诱导的TLR4/NF-κB通路活化的影响

刘鑫，王凤云，吕咪，谢璟仪，车慧

《中国中医药信息杂志》

2025

Sitagliptin inhibits neuronal ferroptosis to alleviate cognitive dysfunction by activating Nrf2-SLC7A11-GPX4 axis in diabetic mice

Han Meng, Han Meng, Zhaoyu Xie, Tao Xu, Sasa Kong, Mengting Wang, Qin Zhu, Yu Zhang, Zhixu Zhu, Miaomiao Wu, Yueqiu Wang, Chao Chen, Jun Han, Hui Che, Hui Che

International Immunopharmacology

DOI

2025

Melatonin impedes NCOA4/ACSL4-dependent ferroptosis by targeting STING to ameliorate diabetic cognitive dysfunction

Tao Xu, Zhaoyu Xie, Yongting Zhao, Zhengrui Ren, Miaomiao Wu, Zhixu Zhu, Han Meng, Han Meng, Yu Zhang, Mengqi Wan, Chao Chen, Jun Han, Hui Che, Hui Che

Bioorganic Chemistry

DOI

2025

Hydrogen sulfide modulates the miR-27a/SLC7A11 axis to inhibit ferroptosis and reduce neuronal damage in ischemic stroke

Yu Zhang, Hongbo Lv, Chao Chen, Zixu Li, Zhaoyu Xie, Miaomiao Wu, Zhixu Zhu, Ying Fan, Jing Li, Qiang Gao, Jun Han, Hui Che, Lan Ma

Journal of Radiation Research and Applied Sciences

DOI

2024

A mechanism linking ferroptosis and ferritinophagy in melatonin-related improvement of diabetic brain injury

Jiaojiao Yu, Yu Zhang, Qin Zhu, Zhengrui Ren, Mengting Wang, Sasa Kong, Hongbo Lv, Tao Xu, Zhaoyu Xie, Han Meng, Jun Han, Jun Han, Hui Che, Hui Che

iScience

DOI

2023

Differentially expressed tRNA-derived fragments and their roles in primary cardiomyocytes stimulated by high glucose

Yong-Ting Zhao, Ruxin Wang, Qi Qin, Jiaojiao Yu, Hui Che, Li-Hong Wang

Frontiers in Endocrinology

DOI

2022

健脾清化颗粒对胃食管反流病脾虚湿热证病证结合大鼠食管黏膜肥大细胞活化的影响

车慧，王凤云，张佳琪，谢璟仪，唐旭东

《世界科学技术-中医药现代化》

2022

High glucose promotes hepatic fibrosis via miR-32/MTA3-mediated epithelial-to-mesenchymal transition

Qiang Li, Zhange Li, Yuan Lin, Hui Che, Ying-Ying Hu, Xujuan Kang, Y. Zhang, Li-Hong Wang, Yong Zhang

Molecular Medicine Reports

DOI

2021

肥大细胞活化对非糜烂性反流病患者食管黏膜瞬时感受器电位香草酸受体1的影响

车慧，王凤云，张佳琪，尹晓岚，谢璟仪，杨斌，唐旭东

《胃肠病学和肝病学杂志》

2020

Melatonin alleviates cardiac fibrosis via inhibiting lncRNA MALAT1/miR‐141‐mediated NLRP3 inflammasome and TGF‐β1/Smads signaling in diabetic cardiomyopathy

Hui Che, Yueqiu Wang, Hui Li, Yang Li, Abbas Sahil, Jie-xuan Lv, Yi-Ning Liu, Zhen-Yu Yang, Ruixue Dong, Hongru Xue, Li-Hong Wang

The FASEB Journal

DOI

2020

Harmine Ameliorates Cognitive Impairment by Inhibiting NLRP3 Inflammasome Activation and Enhancing the BDNF/TrkB Signaling Pathway in STZ-Induced Diabetic Rats

Pei-Fang Liu, Hui Li, Yueqiu Wang, Xiaolin Su, Yang Li, Meiling Yan, Lan Ma, Hui Che

Frontiers in Pharmacology

DOI

2020

miR-150 regulates glucose utilization through targeting GLUT4 in insulin-resistant cardiomyocytes.

Jin Ju, D. Xiao, Nannan Shen, Tong Zhou, Hui Che, Xia Li, Shuqian Zhang, Justine Nyakango Mokembo, Nabanit Kumar Jha, Seth Mikaye Monayo, Zhi-Guo Wang, Yong Zhang

Acta Biochimica et Biophysica Sinica

DOI

2020

Melatonin exerts neuroprotective effects by inhibiting neuronal pyroptosis and autophagy in STZ‐induced diabetic mice

Hui Che, Hui Li, Yang Li, Yueqiu Wang, Zhen-Yu Yang, Ruilie Wang, Li-Hong Wang

The FASEB Journal

DOI

2019

Inhibition of microRNA‐150‐5p alleviates cardiac inflammation and fibrosis via targeting Smad7 in high glucose‐treated cardiac fibroblasts

Hui Che, Yueqiu Wang, Yang Li, Jie-xuan Lv, Hui Li, Yi-Ning Liu, Ruixue Dong, Yongle Sun, Xiao-Dan Xu, Jie Zhao, Li-Hong Wang

Journal of Cellular Physiology

DOI

2019

Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy

Fan Yang, Ying Qin, Yueqiu Wang, Song-Yan Meng, Hui-Min Xian, Hui Che, Jie-xuan Lv, Yang Li, Ya-Han Yu, Yun-Long Bai, Li-Hong Wang

International Journal on Biological Sciences

DOI

2019

Coriolus versicolor alleviates diabetic cardiomyopathy by inhibiting cardiac fibrosis and NLRP3 inflammasome activation

Yueqiu Wang, Hui Li, Yang Li, Yi-Han Zhao, Fangfei Xiong, Yi-Ning Liu, Hongru Xue, Zhen-Yu Yang, Sha Ni, Abbas Sahil, Hui Che, Li-Hong Wang

Phytotherapy Research

DOI

2019

A Novel Circular RNA Mediates Pyroptosis of Diabetic Cardiomyopathy by Functioning as a Competing Endogenous RNA

Fan Yang, Anqi Li, Ying Qin, Hui Che, Yueqiu Wang, Jie-xuan Lv, Yang Li, Hui Li, Er Yue, Xueying Ding, Ya-Han Yu, Yun-Long Bai, Li-Hong Wang

Molecular Therapy: Nucleic Acids

DOI

2019

High glucose promotes hepatic fibrosis via miR-32/MTA3-mediated epithelial-to-mesenchymal transition

Qiang Li, Zhange Li, Yuan Lin, Hui Che, Ying-Ying Hu, Xujuan Kang, Ying Zhang, Li-Hong Wang, Yong Zhang

Molecular Medicine Reports

DOI

2018

PAHSA在糖尿病发病机制中的研究进展

赵永婷，王丽宏，车慧，梁梅花，傅雪莲

《新医学》

2018

LncRNA KCNQ1OT1 Mediates Pyroptosis in Diabetic Cardiomyopathy

Fan Yang, Ying Qin, Yueqiu Wang, Anqi Li, Jie-xuan Lv, Xi Sun, Hui Che, Tian-Shu Han, Song-Yan Meng, Yun-Long Bai, Li-Hong Wang

Cellular Physiology and Biochemistry

DOI

2018

The Relationship Between Liver Enzymes and Insulin Resistance in Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease

Xia Sheng, Hui Che, Q. Ji, Fan Yang, Jie-xuan Lv, Yueqiu Wang, Hui-Min Xian, Li-Hong Wang

Hormone and Metabolic Research

DOI

2018

Coriolus versicolor aqueous extract ameliorates insulin resistance with PI3K/Akt and p38 MAPK signaling pathways involved in diabetic skeletal muscle

Hui-Min Xian, Hui Che, Ying Qin, Fan Yang, Song-Yan Meng, Xiao-Guang Li, Yun-Long Bai, Li-Hong Wang

Phytotherapy Research

DOI

2018

Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy

Fan Yang, Ying Qin, Jie-xuan Lv, Yueqiu Wang, Hui Che, Xi Chen, Ya-Nan Jiang, Anqi Li, Xi Sun, Er Yue, Long Ren, Yang Li, Yun-Long Bai, Li-Hong Wang

Cell Death and Disease

DOI

2018

Silymarin ameliorates diabetic cardiomyopathy via inhibiting TGF‐β1/Smad signaling

Song-Yan Meng, Fan Yang, Yueqiu Wang, Ying Qin, Hui-Min Xian, Hui Che, Li-Hong Wang

Cell Biology International

DOI

2017

microRNA调控糖尿病及其并发症发生发展的研究进展

苏琳，王丽宏，车慧，梁梅花，付雪莲

《临床和实验医学杂志》

2017

The potential therapeutic effects of glucagon like peptide -1 receptor agonists in patients with diabetes mellitus induced erectile dysfunction

Fengjiao Dong, Li-Hong Wang, Hui Che, Mei-Hua Liang

DOI

2017

MicroRNA-27a Promotes Inefficient Lysosomal Clearance in the Hippocampi of Rats Following Chronic Brain Hypoperfusion

Hui Che, Yan Yan, Xiaohui Kang, Fei Guo, Mei-ling Yan, Huai-Lei Liu, Xu Hou, Tong Liu, De-Kang Zong, Lin-Lin Sun, Ya-Nan Bao, Li-Hua Sun, Bao-feng Yang, Jing Ai

Molecular Neurobiology

DOI

2016

LncRNA与糖尿病血管并发症

张蝶，王丽宏，车慧，傅雪莲，梁梅花

《东南大学学报(医学版)》

2016

LNCRNAと糖尿病血管合併症【JST・京大機械翻訳】

Die Zhang, Li-Hong Wang, Hui Che, Xuelian Fu, Mei-Hua Liang

2016

MDG-1 prevents high glucose-induced cytotoxicity and inflammation in rat brain microvessel endothelial cells

Qun Gu, Ming Shen, R. Sun, Hui Che, G. Cui, Xiaohong Wen, Hui Gong, X. Yao, M. Qian

2016

Regulation of Insulin Resistance by Multiple MiRNAs via Targeting the GLUT4 Signalling Pathway

Tong Zhou, Xian-Hong Meng, Hui Che, Nannan Shen, D. Xiao, Xiaotong Song, Mei-Hua Liang, Xuelian Fu, Jiaming Ju, Yang Li, Chao-Qian Xu, Yong Zhang, Li-Hong Wang

Cellular Physiology and Biochemistry

DOI

2015

长链非编码RNA对脂肪组织作用的研究进展

李佳宁，车慧，梁梅花，傅雪莲，王丽宏

《东南大学学报(医学版)》

2015

MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion

Li-Hua Sun, Mei-ling Yan, Xue-Ling Hu, Lilin Peng, Hui Che, Ya-Nan Bao, Fei Guo, Tong Liu, Xin Chen, Rong Zhang, Tao Ban, Ning Wang, Huai-Lei Liu, Xu Hou, Jing Ai

Molecular Neurodegeneration

DOI

2013

MicroRNA-195 Protects Against Dementia Induced by Chronic Brain Hypoperfusion via Its Anti-Amyloidogenic Effect in Rats

Jing Ai, Li-Hua Sun, Hui Che, Rong Zhang, Tian-Zhu Zhang, Wanchen Wu, Xiao-Lin Su, Xin Chen, Guang Yang, Kang Li, Ning-Zhi Wang, Tao Ban, Ya-Nan Bao, Fei Guo, Hui-Fang Niu, Yu-Lan Zhu, Xiu-Ying Zhu, Shi-Guang Zhao, Bao-feng Yang

Journal of Neuroscience

DOI

2011

Influence of fluvastatin on cardiac function and baroreflex sensitivity in diabetic rats

Fang Xie, Chao Sun, Li-Hua Sun, Jing-yuan Li, Xin Chen, Hui Che, Guan-yi Lu, Bao-feng Yang, Jing Ai

Acta Pharmacologica Sinica

DOI

Cellular Physiology and Biochemistry Cellular Physiology and Biochemistry Expression of Amyloid-associated Mirnas in Both the Forebrain Cortex and Hippocampus of Middle-aged Rat Key Words Aging @bullet Micrornas @bullet App @bullet Bace1 @bullet Learning @bullet Memory Cellular Physiology and Bioche

Jing Ai, Bao-feng Yang, Hui Che, Li-Hua Sun, Fei Guo, Hui-Fang Niu, Xiao-Lin Su, Ya-Nan Bao, Donna Zidong, Fu, Huai-Lei Liu, Xu Hou

研究方向

】非编码RNA在糖尿病及其并发症中的作用机制研究 【

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