蒋晨｜复旦大学｜学者主页

2026

AI‐Optimized 3D‐Printed Dual‐Layer Implant: Resolving Chemo‐Immunotherapy Sequential Administration Dilemma for Colorectal Cancer Peritoneal Metastasis

W T Tang, Bing Liu, Ye Liu, Shuai Wang, Tiancong Zhao, Jiaqi Wang, Chen Jiang, Tao Sun

Advanced Materials

2025

Shutting Down the ‘Language Encoder’: A Pathogen‐Derived Nano‐Interferer Disrupt Sialylation Metabolism and Reprogram Intercellular Communication in Glioblastoma

Jingyi Zhou, Zonghua Tian, Yun Chen, Zhenhao Zhao, Xuwen Li, Haolin Song, Hongrui Fan, Yuxing Wu, Dongxu Wu, Shuo Geng, Yuchen Liu, Tao Sun, Chen Jiang

Advanced Materials

DOI

2025

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Zonghua Tian, Yun Chen, Jingyi Zhou, Shilin Zhang, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang

Advanced Science

DOI

2025

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

Jingyi Zhou, Chen Jiang

Advanced Science

DOI

2025

Intravenous Multifunctional Nanotherapy for Treating Dry Age‐Related Macular Degeneration

Xinyi Zhao, Weiyi Xia, Yu Wang, Yihan Zhang, Zheng Zhou, Peixin Liu, Shilin Zhang, Zihan Zheng, Weiai Shen, Shujie Zhang, Jing Yao, Tao Sun, Chen Jiang, Chen Zhao

Advanced Healthcare Materials

DOI

2025

Mitocytosis-inducing nanoparticles alleviate gemcitabine resistance via dual disruption of pyrimidine synthesis and redox homeostasis in pancreatic ductal adenocarcinoma

Yu Wang, Hongrui Fan, Qinjun Chen, Haolin Song, Xuwen Li, Boyu Su, Tao Sun, Leilei Cheng, Chen Jiang

Biomaterials

DOI

2025

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

Hongrui Fan, Hongyi Chen, Haolin Song, Chufeng Li, Yu Wang, Zhenhao Zhao, Qin Guo, Xuwen Li, Mingxuan Liu, Tao Sun, Chen Jiang

Advanced Science

DOI

2025

NIR-II Luminescent Nanothermometer for Precise Assessment of Ischemic Stroke

Xiaochen Qiu, Wei Yuan, Chen Jiang, Wei Feng, Fuyou Li

ACS Applied Materials & Interfaces

DOI

2025

Multiple‐Stimuli‐Responsive Biomimetic Polypyrrole Delivery System for Synergistic Regulation and Restoration of Epileptic Foci

Zheng Zhou, Mingxuan Liu, Haoyu You, Boyu Su, Yuxing Wu, Shilin Zhang, Tao Sun, Chen Jiang

Advanced Functional Materials

DOI

2025

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang

Advanced Science

DOI

2025

Disrupting Tumor Lactate Homeostasis to Sensitize Chemo-Immunotherapy Using a Glucose-Disguised Lactate Interceptor

Xuwen Li, Shuo Geng, Qinjun Chen, Boyu Su, Haolin Song, Jingyi Zhou, Ru Jia, Hongrui Fan, Chufeng Li, Yu Wang, Zonghua Tian, Tao Sun, Chen Jiang

ACS Nano

DOI

2025

Manganese-based virus-mimicking nanomedicine with triple immunomodulatory functions inhibits breast cancer brain metastasis

Zhenhao Zhao, Jingyi Zhou, Xuwen Li, Tongyu Zhang, Zonghua Tian, Tao Sun, Chen Jiang

Biomaterials

DOI

2025

Engineered Intelligent Microenvironment Responsive Prodrug Conjugates Navigated by Bioinspired Lipoproteins for Reversing Liver Fibrosis

Mingzhu Fang, Boyu Su, Shilin Zhang, Fangxin Li, Yun Guo, Qinjun Chen, Yuxing Wu, Huiyi Liu, Chen Jiang, Tao Sun

Small Methods

DOI

2025

PROTAC-loaded nanocapsules degrading BRD4 for radio-chemotherapy sensitization in glioblastoma

Yun Guo, Mingzhu Fang, Shilin Zhang, Zheng Zhou, Zonghua Tian, Haoyu You, Yun Chen, Jingyi Zhou, Xiaobao Yang, Yunke Bi, Chen Jiang, Tao Sun

Acta Pharmaceutica Sinica B

DOI

2025

Transcytosis-Triggering Nanoparticles for Overcoming Stromal Barriers and Reversing Immunosuppression in Pancreatic Cancer Combinatorial Therapy

Shilin Zhang, Haoyu You, Hongrui Fan, Yun Chen, Haolin Song, Zhenhao Zhao, Qinjun Chen, Yu Wang, Zonghua Tian, Yuxing Wu, Zheng Zhou, Yun Guo, Boyu Su, Xuwen Li, Ru Jia, Mingzhu Fang, Chen Jiang, Tao Sun

Nano Letters

DOI

2025

Polymer-engineered PROTAC nanovehicles amplify synergistic effects with temozolomide by BRD4 degradation

Yun Guo, Haoyu You, Yiyang Li, Zheng Zhou, Zonghua Tian, Chen Jiang, Tao Sun

Biomaterials Science

DOI

2024

Metabolic Nanoregulators Induce Ferroptosis and Change Metabolite Flow to Reverse Immunosuppressive Tumor Microenvironment

Yu Wang, Qinjun Chen, Yifan Luo, Yangqi Qu, Xuwen Li, Haolin Song, Chufeng Li, Yiwen Zhang, Tao Sun, Chen Jiang

ACS Nano

DOI

2024

PROTAC delivery in tumor immunotherapy: Where are we and where are we going?

Yiyang Li, Yike Wu, Sihan Gao, Tao Sun, Chen Jiang

Journal of Controlled Release

DOI

2024

Size and Charge Dual‐Switchable Nanoparticles for Achieving Chemosensitization and Immune Infiltration against Pancreatic Ductal Adenocarcinoma

Haolin Song, Hongyi Chen, Qinjun Chen, Hongrui Fan, Chufeng Li, Yu Wang, Shilin Zhang, Xuwen Li, Boyu Su, Tao Sun, Chen Jiang

Advanced Functional Materials

DOI

2024

Cabozantinib-encapsulated and maytansine-conjugated high-density lipoprotein for immunotherapy in colorectal cancer

Chao Zheng, Linyang Jiang, Xiang Gong, Wen Zhang, Rong Pu, Yuan Zhang, Mengmeng Zhao, Chen Jiang, Hao Wang, Pengcheng Zhang, Yaping Li

Journal of Controlled Release

DOI

2024

A Peptide‐Drug Conjugate‐Based Nanoplatform for Immunometabolic Activation and In Situ Nerve Regeneration in Advanced‐Stage Alzheimer's Disease

Peixin Liu, Tongyu Zhang, Yuxing Wu, Qinjun Chen, Tao Sun, Chen Jiang

Advanced Materials

DOI

2024

Intelligent micelles for on-demand drug delivery targeting extracellular matrix of pancreatic cancer

Chufeng Li, Qinjun Chen, Chen Jiang

Journal of Controlled Release

DOI

2024

Recent advances in biomimetic strategies for the immunotherapy of glioblastoma

Haoyu You, Shuo Geng, Shangkuo Li, Mohammad Imani, Davide Brambilla, Tao Sun, Chen Jiang

Biomaterials

DOI

2024

Reconciling the Cooperative–Competitive Patterns among Tumor and Immune Cells for Triple‐Negative Breast Cancer Treatment Using Multimodule Nanocomplexes

Xuwen Li, Qin Guo, Qinjun Chen, Yongchao Chu, Yiwen Zhang, Hongyi Chen, Zhenhao Zhao, Yu Wang, Yifan Luo, Chufeng Li, Haoyu You, Haolin Song, Boyu Su, Kiyumars Jalili, Tao Sun, Chen Jiang

Advanced Materials

DOI

2024

Therapeutic regulation of epigenetics in cancer treatment through drug delivery systems

Boyu Su, Shangkuo Li, Shuo Geng, Davide Brambilla, Rong Sun, Tao Sun, Tao Sun, Chen Jiang

Nano Today

DOI

2023

Intelligent Delivery Systems in Tumor Metabolism Regulation: Exploring the Path Ahead

Xuwen Li, Tao Sun, Chen Jiang

Advanced Materials

DOI

2023

Nanomaterials for brain metastasis

Zhenhao Zhao, Yun Chen, Tao Sun, Chen Jiang

Journal of Controlled Release

DOI

2023

Pleiotropic Microenvironment Remodeling Micelles for Cerebral Ischemia-Reperfusion Injury Therapy by Inhibiting Neuronal Ferroptosis and Glial Overactivation

Chao Li, Yuxing Wu, Qinjun Chen, Yifan Luo, Peixin Liu, Zheng Zhou, Zhenhao Zhao, Tongyu Zhang, Boyu Su, Tao Sun, Chen Jiang

ACS Nano

DOI

2023

Gradient tumor microenvironment-promoted penetrating micelles for hypoxia relief and immunosuppression reversion in pancreatic cancer treatment

Yifan Luo, Chao Li, Yiwen Zhang, Peixin Liu, Hongyi Chen, Zhenhao Zhao, Yu Wang, Zheng Zhou, Haolin Song, Boyu Su, Chufeng Li, Xuwen Li, Tongyu Zhang, Haoyu You, Yuxing Wu, Zonghua Tian, Shilin Zhang, Yun Guo, Hongrui Fan, Qinjun Chen, Chen Jiang, Tao Sun

Acta Biomaterialia

DOI

2023

Nanomaterials with dual immunomodulatory functions for synergistic therapy of breast cancer brain metastases

Zhenhao Zhao, Chufeng Li, Yiwen Zhang, Chao Li, Yongchao Chu, Xuwen Li, Peixin Liu, Hongyi Chen, Yu Wang, Boyu Su, Qinjun Chen, Tao Sun, Chen Jiang

Bioactive Materials

DOI

2023

ROS/Electro Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberrant Circuits and Inflammatory Microenvironment

Zheng Zhou, Keying Li, Yun Guo, Peixin Liu, Qinjun Chen, Hongrui Fan, Tao Sun, Chen Jiang

ACS Nano

DOI

2023

Transcytosis Mediated Deep Tumor Penetration for Enhanced Chemotherapy and Immune Activation of Pancreatic Cancer

Hongyi Chen, Haolin Song, Yifan Luo, Chufeng Li, Yu Wang, Jie Liu, Feifei Luo, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang

Advanced Functional Materials

DOI

2023

Stimuli-responsive drug delivery systems triggered by intracellular or subcellular microenvironments

Tao Sun, Chen Jiang

Advanced Drug Delivery Reviews

DOI

2023

Bioinspired nanoerythrocytes for metabolic microenvironment remodeling and long-term prognosis promoting of acute ischemic stroke

Peixin Liu, Tongyu Zhang, Chao Li, Yiwen Zhang, Zheng Zhou, Zhenhao Zhao, Qinjun Chen, Tao Sun, Chen Jiang

Nano Today

DOI

2023

Compound Nanoemulsion Combined with Differentiation/Cytotoxicity Drugs for Modulating Breast Cancer Stemness

Yongchao Chu, Boyu Su, Yifan Luo, Chao Li, Yiwen Zhang, Peixin Liu, Hongyi Chen, Maciej Serda, Chen Jiang, Tao Sun

Molecular Pharmaceutics

DOI

2022

纳米仿生型肿瘤疫苗的研究进展

杨玥，王海燕，孙野，孙涛，蒋晨

《药学学报》

2022

载奥沙利铂的还原敏感型四氧化三铁纳米粒的体内外靶向性评价

汪瑜，陈钦俊，孙涛，蒋晨

《药学学报》

2022

Microenvironment-tailored micelles restrain carcinoma-astrocyte crosstalk for brain metastasis

Zhenhao Zhao, Yujie Zhang, Chao Li, Xuwen Li, Yongchao Chu, Qin Guo, Yiwen Zhang, Weiyi Xia, Peixin Liu, Hongyi Chen, Yu Wang, Chufeng Li, Tao Sun, Chen Jiang

Journal of Controlled Release

DOI

2022

Extracellular vesicle-based macromolecule delivery systems in cancer immunotherapy

Hongyi Chen, Tao Sun, Chen Jiang

Journal of Controlled Release

DOI

2022

Transformable “Tubulin Traps” Interfere with Mitochondrial Autophagy and Promote the Elimination of Glioblastoma

Yiwen Zhang, Haoyu You, Zhenhao Zhao, Yifan Luo, Chao Li, Peixin Liu, Hongyi Chen, Yu Wang, Zheng Zhou, Tao Sun, Chen Jiang

Advanced Functional Materials

DOI

2022

ROS-removing nano-medicine for navigating inflammatory microenvironment to enhance anti-epileptic therapy

Zheng Zhou, Keying Li, Yongchao Chu, Chao Li, Tongyu Zhang, Peixin Liu, Tao Sun, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2022

A Triple Therapeutic Strategy with Antiexosomal Iron Efflux for Enhanced Ferroptosis Therapy and Immunotherapy

Yu Wang, Qinjun Chen, Haolin Song, Yiwen Zhang, Hongyi Chen, Peixin Liu, Tao Sun, Chen Jiang

Small

DOI

2022

A neutrophil-biomimic platform for eradicating metastatic breast cancer stem-like cells by redox microenvironment modulation and hypoxia-triggered differentiation therapy

Yongchao Chu, Yifan Luo, Boyu Su, Chao Li, Qin Guo, Yiwen Zhang, Peixin Liu, Hongyi Chen, Zhenhao Zhao, Zheng Zhou, Yu Wang, Chen Jiang, Tao Sun

Acta Pharmaceutica Sinica B

DOI

2022

Smart hypoxia-responsive transformable and charge-reversible nanoparticles for the deep penetration and tumor microenvironment modulation of pancreatic cancer

Hongyi Chen, Qin Guo, Yongchao Chu, Chao Li, Yiwen Zhang, Peixin Liu, Zhenhao Zhao, Yu Wang, Yifan Luo, Zheng Zhou, Tongyu Zhang, Haolin Song, Xuwen Li, Chufeng Li, Boyu Su, Haoyu You, Tao Sun, Chen Jiang

Biomaterials

DOI

2022

Brain‐targeting drug delivery systems

Peixin Liu, Chen Jiang

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology

DOI

2022

Penetrating Micelle for Reversing Immunosuppression and Drug Resistance in Pancreatic Cancer Treatment

Qinjun Chen, Qingbing Wang, Yu Wang, Yongchao Chu, Yifan Luo, Haoyu You, Boyu Su, Chao Li, Qin Guo, Tao Sun, Chen Jiang

Small

DOI

2022

Emerging landscapes of nanosystems based on pre-metastatic microenvironment for cancer theranostics

Yongchao Chu, Tao Sun, Chen Jiang

Chinese Chemical Letters

DOI

2022

Physicochemical Characterization and Pharmacological Evaluation of Novel Propofol Micelles with Low-Lipid and Low-Free Propofol

Yongchao Chu, Tao Sun, Zichen Xie, Keyu Sun, Chen Jiang

Pharmaceutics

DOI

2021

Exosomes derived from immunogenically dying tumor cells as a versatile tool for vaccination against pancreatic cancer

Wenxi Zhou, Xinli Chen, Yu Zhou, Si Shi, Chen Liang, Xianjun Yu, Hongyi Chen, Qin Guo, Yiwen Zhang, Peixin Liu, Chao Li, Yongchao Chu, Yifan Luo, Yu Wang, Zheng Zhou, Zhenhao Zhao, Qinjun Chen, Tao Sun, Chen Jiang

Biomaterials

DOI

2021

A Micro‐Environment Regulator for Filling the Clinical Treatment Gap after a Glioblastoma Operation

Yiwen Zhang, Haoyu You, Yaoben Wang, Qinjun Chen, Qin Guo, Yongchao Chu, Chao Li, Wenxi Zhou, Hongyi Chen, Peixin Liu, Yu Wang, Zhenhao Zhao, Zheng Zhou, Yifan Luo, Xuwen Li, Tongyu Zhang, Haolin Song, Chufeng Li, Boyu Su, Tao Sun, Yunke Bi, Lin Yu, Chen Jiang

Advanced Healthcare Materials

DOI

2021

Intravenous route to choroidal neovascularization by macrophage-disguised nanocarriers for mTOR modulation

Weiyi Xia, Chao Li, Qinjun Chen, Jiancheng Huang, Zhenhao Zhao, Peixin Liu, Kai Xu, Lei Li, Fangyuan Hu, Shujie Zhang, Tao Sun, Chen Jiang, Chen Zhao

Acta Pharmaceutica Sinica B

DOI

2021

Macrophage‐Disguised Manganese Dioxide Nanoparticles for Neuroprotection by Reducing Oxidative Stress and Modulating Inflammatory Microenvironment in Acute Ischemic Stroke

Chao Li, Zhenhao Zhao, Yifan Luo, Tingting Ning, Peixin Liu, Qinjun Chen, Yongchao Chu, Qin Guo, Yiwen Zhang, Wenxi Zhou, Hongyi Chen, Zheng Zhou, Yu Wang, Boyu Su, Haoyu You, Tongyu Zhang, Xuwen Li, Haolin Song, Chufeng Li, Tao Sun, Chen Jiang

Advanced Science

DOI

2021

A Versatile Theranostic Platform for Colorectal Cancer Peritoneal Metastases: Real‐Time Tumor‐Tracking and Photothermal‐Enhanced Chemotherapy

Tao Sun, Guang‐Ping Zhang, Tingting Ning, Qinjun Chen, Yongchao Chu, Yifan Luo, Haoyu You, Boyu Su, Chao Li, Qin Guo, Chen Jiang

Advanced Science

DOI

2021

Sequentially Triggered Bacterial Outer Membrane Vesicles for Macrophage Metabolism Modulation and Tumor Metastasis Suppression

Qin Guo, Xuwen Li, Wenxi Zhou, Yongchao Chu, Qinjun Chen, Yiwen Zhang, Chao Li, Hongyi Chen, Peixin Liu, Zhenhao Zhao, Yu Wang, Zheng Zhou, Yifan Luo, Chufeng Li, Haoyu You, Haolin Song, Boyu Su, Tongyu Zhang, Tao Sun, Chen Jiang

ACS Nano

DOI

2021

Biomimetic Dendrimer–Peptide Conjugates for Early Multi‐Target Therapy of Alzheimer's Disease by Inflammatory Microenvironment Modulation

Peixin Liu, Tongyu Zhang, Qinjun Chen, Chao Li, Yongchao Chu, Qin Guo, Yiwen Zhang, Wenxi Zhou, Hongyi Chen, Zheng Zhou, Yu Wang, Zhenhao Zhao, Yifan Luo, Xuwen Li, Haolin Song, Boyu Su, Chufeng Li, Tao Sun, Chen Jiang

Advanced Materials

DOI

2021

Recent advances on drug delivery nanocarriers for cerebral disorders

Zheng Zhou, Tao Sun, Chen Jiang

Biomedical Materials

DOI

2021

Postoperative cancer treatments: In-situ delivery system designed on demand

Yiwen Zhang, Chen Jiang

Journal of Controlled Release

DOI

2021

NIR-Light-Intensified Hypoxic Microenvironment for Cascaded Supra-Prodrug Activation and Synergistic Chemo/Photodynamic Cancer Therapy

Hongzhong Chen, Tao Sun, Weiwei Zeng, Xiaowei Zeng, Lin Mei, Chen Jiang, Yanli Zhao

ACS Materials Letters

DOI

2020

Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies

Liang Han, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2020

Click-Nucleic-Acid-Containing Codelivery System Inducing Collapse of Cellular Homeostasis for Tumor Therapy through Bidirectional Regulation of Autophagy and Glycolysis

Qin Guo, Qinjun Chen, Yujie Zhang, Wenxi Zhou, Xuwen Li, Chao Li, Yiwen Zhang, Hongyi Chen, Peixin Liu, Yongchao Chu, Tao Sun, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2020

Recent advances in nanomedicines for the treatment of ischemic stroke

Chao L. Li, Tao Sun, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2020

Penetrable Nanoplatform for “Cold” Tumor Immune Microenvironment Reeducation

Qinjun Chen, Yongqing He, Yu Wang, Chao Li, Yujie Zhang, Qin Guo, Yiwen Zhang, Yongchao Chu, Peixin Liu, Hongyi Chen, Zheng Zhou, Wenxi Zhou, Zhenhao Zhao, Xiaomin Li, Tao Sun, Chen Jiang

Advanced Science

DOI

2020

Carry-On Nitric-Oxide Luggage for Enhanced Chemotherapeutic Efficacy

Tao Sun, Yunhui Ding, Xiaofei Wang, Kai Zhang, Guang‐Ping Zhang, Donghui Liang, Kunjiao Yu, Yongchao Chu, Qinjun Chen, Chen Jiang

Nano Letters

DOI

2020

Supramolecular Hunter Stationed on Red Blood Cells for Detoxification Based on Specific Molecular Recognition

Chao Li, Zichen Xie, Qinjun Chen, Yujie Zhang, Yongchao Chu, Qin Guo, Wenxi Zhou, Yiwen Zhang, Peixin Liu, Hongyi Chen, Chen Jiang, Keyu Sun, Tao Sun

ACS Nano

DOI

2020

Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic

Tao Sun, Guang‐Ping Zhang, Zhongyuan Guo, Qinjun Chen, Yujie Zhang, Yongchao Chu, Qin Guo, Chao Li, Wenxi Zhou, Yiwen Zhang, Peixin Liu, Hongyi Chen, Haijun Yu, Liping Jiang, Chen Jiang

Journal of Controlled Release

DOI

2020

Theranostic nanoparticles enabling the release of phosphorylated gemcitabine for advanced pancreatic cancer therapy

Qingbing Wang, Xingjun Zhu, Zhiyuan Wu, Tao Sun, Wei Huang, Zhongmin Wang, Xiaoyi Ding, Chen Jiang, Fuyou Li

Journal of Materials Chemistry B

DOI

2020

Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment

Wenxi Zhou, Yu Zhou, Xinli Chen, Tingting Ning, Hongyi Chen, Qin Guo, Yiwen Zhang, Peixin Liu, Yujie Zhang, Chao Li, Yongchao Chu, Tao Sun, Chen Jiang

Biomaterials

DOI

2020

Delivery strategies for macromolecular drugs in cancer therapy

Qin Guo, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2019

Dynamic covalent chemistry-regulated stimuli-activatable drug delivery systems for improved cancer therapy

Qiwen Zhu, Madiha Saeed, Rundi Song, Tao Sun, Chen Jiang, Haijun Yu

Chinese Chemical Letters

DOI

2019

Dandelion‐Like Tailorable Nanoparticles for Tumor Microenvironment Modulation

Qin Guo, Xi He, Chao Li, Yongqing He, Yiying Peng, Yu Zhang, Yifei Lü, Xinli Chen, Yujie Zhang, Qinjun Chen, Tao Sun, Chen Jiang

Advanced Science

DOI

2019

Nano-engineered lymphocytes for alleviating suppressive tumor immune microenvironment

Lisha Liu, Qinjun Chen, Chunhui Ruan, Xinli Chen, Xi He, Yu Zhang, Yujie Zhang, Yifei Lü, Qin Guo, Wenxi Zhou, Chao Li, Tao Sun, Chen Jiang

Applied Materials Today

DOI

2019

Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein

Yu Zhang, Yujie Zhang, Qin Guo, Zhongyuan Guo, Xinli Chen, Lisha Liu, Chao Li, Qinjun Chen, Xi He, Yifei Lü, Tao Sun, Yongzhuo Huang, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2019

Codelivery Nanosystem Targeting the Deep Microenvironment of Pancreatic Cancer

Xinli Chen, Wenxi Zhou, Chen Liang, Si Shi, Xianjun Yu, Qinjun Chen, Tao Sun, Yifei Lü, Yujie Zhang, Qin Guo, Chao Li, Yu Zhang, Chen Jiang

Nano Letters

DOI

2019

Microthrombus‐Targeting Micelles for Neurovascular Remodeling and Enhanced Microcirculatory Perfusion in Acute Ischemic Stroke

Yifei Lü, Chao Li, Qinjun Chen, Peixin Liu, Qin Guo, Yu Zhang, Xinli Chen, Yujie Zhang, Wenxi Zhou, Donghui Liang, Yiwen Zhang, Tao Sun, Weigen Lu, Chen Jiang

Advanced Materials

DOI

2019

Drug Delivery: Activated Platelets‐Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer (Adv. Funct. Mater. 13/2019)

Yujie Zhang, Xi Zhu, Xinli Chen, Qinjun Chen, Wenxi Zhou, Qin Guo, Yifei Lü, Chao Li, Yu Xin Zhang, Donghui Liang, Tao Sun, Xunbin Wei, Chen Jiang

Advanced Functional Materials

DOI

2019

Pre-blocked molecular shuttle as an in-situ real-time theranostics

Tao Sun, Guang‐Ping Zhang, Qingbing Wang, Zhongyuan Guo, Qinjun Chen, Xinli Chen, Yifei Lü, Yu Xin Zhang, Yujie Zhang, Qin Guo, Xiang Gao, Yongzhong Cheng, Chen Jiang

Biomaterials

DOI

2019

Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)

Yifei Lü, Zhongyuan Guo, Yujie Zhang, Chao Li, Yu Zhang, Qin Guo, Qinjun Chen, Xinli Chen, Xi He, Lisha Liu, Chunhui Ruan, Tao Sun, Bin Ji, Weigen Lu, Chen Jiang

Advanced Science

DOI

2019

Tumor Microenvironment‐Triggered Aggregated Magnetic Nanoparticles for Reinforced Image‐Guided Immunogenic Chemotherapy

Qinjun Chen, Lisha Liu, Yifei Lü, Xinli Chen, Yujie Zhang, Wenxi Zhou, Qin Guo, Chao Li, Yiwen Zhang, Yu Xin Zhang, Donghui Liang, Tao Sun, Chen Jiang

Advanced Science

DOI

2019

Activated Platelets‐Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer

Yujie Zhang, Xi Zhu, Xinli Chen, Qinjun Chen, Wenxi Zhou, Qin Guo, Yifei Lü, Chao Li, Yu Xin Zhang, Donghui Liang, Tao Sun, Xunbin Wei, Chen Jiang

Advanced Functional Materials

DOI

2019

Bone marrow mesenchymal stem cells-derived exosomes for penetrating and targeted chemotherapy of pancreatic cancer

Yu Zhou, Wenxi Zhou, Xinli Chen, Qingbing Wang, Chao Li, Qinjun Chen, Yu Zhang, Yifei Lü, Xiaoyi Ding, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2019

GLUT1-mediated effective anti-miRNA21 pompon for cancer therapy

Qin Guo, Chao Li, Wenxi Zhou, Xinli Chen, Yu Zhang, Yifei Lü, Yujie Zhang, Qinjun Chen, Donghui Liang, Tao Sun, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2018

Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia

Yifei Lü, Zhongyuan Guo, Yujie Zhang, Chao Li, Yu Zhang, Qin Guo, Qinjun Chen, Xinli Chen, Xi He, Lisha Liu, Chunhui Ruan, Tao Sun, Bin Ji, Weigen Lu, Chen Jiang

Advanced Science

DOI

2018

Platelet for drug delivery

Yifei Lü, Quanyin Hu, Chen Jiang, Zhen Nan Gu

Current Opinion in Biotechnology

DOI

2018

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

Qian Chen, Chao Wang, Xudong Zhang, Guojun Chen, Quanyin Hu, Hongjun Li, Jinqiang Wang, Di Wen, Yuqi Zhang, Yifei Lü, Guang Yong Yang, Chen Jiang, Jun Wang, Gianpietro Dotti, Zhen Nan Gu

Nature Nanotechnology

DOI

2018

Double-sided effect of tumor microenvironment on platelets targeting nanoparticles

Xinli Chen, Qingbing Wang, Lisha Liu, Tao Sun, Wenxi Zhou, Qinjun Chen, Yifei Lü, Xi He, Yu Zhang, Yujie Zhang, Chunhui Ruan, Qin Guo, Chao Li, Chen Jiang

Biomaterials

DOI

2018

Endogenous albumin-mediated delivery of redox-responsive paclitaxel-loaded micelles for targeted cancer therapy

Yujie Zhang, Zhongyuan Guo, Zhonglian Cao, Wenxi Zhou, Yu Xin Zhang, Qinjun Chen, Yifei Lü, Xinli Chen, Qin Guo, Chao Li, Donghui Liang, Tao Sun, Chen Jiang

Biomaterials

DOI

2018

Dimeric Prodrug Self-Delivery Nanoparticles with Enhanced Drug Loading and Bioreduction Responsiveness for Targeted Cancer Therapy

Xi He, Kaimin Cai, Yu Xin Zhang, Yifei Lü, Qin Guo, Yujie Zhang, Lisha Liu, Chunhui Ruan, Qinjun Chen, Xinli Chen, Chao Li, Tao Sun, Jianjun Cheng, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2018

A targeting theranostics nanomedicine as an alternative approach for hyperthermia perfusion

Tao Sun, Guang‐Ping Zhang, Qingbing Wang, Qinjun Chen, Xinli Chen, Yifei Lü, Lisha Liu, Yu Xin Zhang, Xi He, Chunhui Ruan, Yujie Zhang, Qin Guo, Chen Jiang

Biomaterials

DOI

2018

Reactive Oxygen Species-Biodegradable Gene Carrier for the Targeting Therapy of Breast Cancer

Chunhui Ruan, Lisha Liu, Qingbing Wang, Xinli Chen, Qinjun Chen, Yifei Lü, Yu Zhang, Xi He, Yujie Zhang, Qin Guo, Tao Sun, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2018

Sequentially Triggered Nanoparticles with Tumor Penetration and Intelligent Drug Release for Pancreatic Cancer Therapy

Xi He, Xinli Chen, Lisha Liu, Yu Zhang, Yifei Lü, Yujie Zhang, Qinjun Chen, Chunhui Ruan, Qin Guo, Chao Li, Tao Sun, Chen Jiang

Advanced Science

DOI

2018

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

Yu Xin Zhang, Kaimin Cai, Chao Li, Qin Guo, Qinjun Chen, Xi He, Lisha Liu, Yujie Zhang, Yifei Lü, Xinli Chen, Tao Sun, Yongzhuo Huang, Jianjun Cheng, Chen Jiang

Nano Letters

DOI

2018

Enhanced bioreduction-responsive diselenide-based dimeric prodrug nanoparticles for triple negative breast cancer therapy

Xi He, Jinxiao Zhang, Chao Li, Yu Xin Zhang, Yifei Lü, Yujie Zhang, Lisha Liu, Chunhui Ruan, Qinjun Chen, Xinli Chen, Qin Guo, Tao Sun, Jianjun Cheng, Chen Jiang

Theranostics

DOI

2018

Platinum-Based Nanovectors Engineered with Immuno-Modulating Adjuvant for Inhibiting Tumor growth and Promoting Immunity

Lisha Liu, Qinjun Chen, Chunhui Ruan, Xinli Chen, Yu Zhang, Xi He, Yujie Zhang, Yifei Lü, Qin Guo, Tao Sun, Hao Wang, Chen Jiang

Theranostics

DOI

2017

Dehydroascorbic Acid and pGPMA Dual Modified pH-Sensitive Polymeric Micelles for Target Treatment of Liver Cancer

Haojun Ma, Chen Jiang

Journal of Pharmaceutical Sciences

DOI

2017

Brain-Targeted Polymers for Gene Delivery in the Treatment of Brain Diseases

Yifei Lü, Chen Jiang

Topics in Current Chemistry

DOI

2017

Supramolecular amphiphiles based on cyclodextrin and hydrophobic drugs

Tao Sun, Qingbing Wang, Yunke Bi, Xinli Chen, Lisha Liu, Chunhui Ruan, Zhifeng Zhao, Chen Jiang

Journal of Materials Chemistry B

DOI

2017

Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites

Fan Xu, Huihai Zhong, Ya Chang, Dongdong Li, Hongyue Jin, Meng Zhang, Huiyuan Wang, Chen Jiang, Youqing Shen, Yongzhuo Huang

Biomaterials

DOI

2017

Biomacromolecules as carriers in drug delivery and tissue engineering

Yujie Zhang, Tao Sun, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2017

Substance P-modified human serum albumin nanoparticles loaded with paclitaxel for targeted therapy of glioma

Chunhui Ruan, Lisha Liu, Yifei Lü, Yu Xin Zhang, Xi He, Xinli Chen, Yujie Zhang, Qinjun Chen, Qin Guo, Tao Sun, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2017

Substance P Mediated DGLs Complexing with DACHPt for Targeting Therapy of Glioma

Tao Sun, Xutao Jiang, Qingbing Wang, Qinjun Chen, Yifei Lü, Lisha Liu, Yu Zhang, Xi He, Chunhui Ruan, Yujie Zhang, Qin Guo, Yaohua Liu, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2017

Tumor-Targeting Micelles Based on Linear–Dendritic PEG–PTX8 Conjugate for Triple Negative Breast Cancer Therapy

Yujie Zhang, Yifei Lü, Yu Zhang, Xi He, Qinjun Chen, Lisha Liu, Xinli Chen, Chunhui Ruan, Tao Sun, Chen Jiang

Molecular Pharmaceutics

DOI

2017

Dehydroascorbic Acids-modified Polymer Micelles Target Cancer Cells to Enhance Anti-tumor Efficacy of Paclitaxel

Xiaoyu Pei, Feifei Luo, Jun Zhang, Wulian Chen, Chen Jiang, Jie Liu

Scientific Reports

DOI

2017

ROS-Switchable Polymeric Nanoplatform with Stimuli-Responsive Release for Active Targeted Drug Delivery to Breast Cancer

Yu Zhang, Qin Guo, Sai An, Yifei Lü, Jianfeng Li, Xi He, Lisha Liu, Yujie Zhang, Tao Sun, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2017

Biomimetic Human Serum Albumin Nanoparticle for Efficiently Targeting Therapy to Metastatic Breast Cancers

Lisha Liu, Yunke Bi, Muru Zhou, Xinli Chen, Xi He, Yujie Zhang, Tao Sun, Chunhui Ruan, Qingjun Chen, Hao Wang, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2016

Chemotherapy: Amino Acid Metabolism Abnormity and Microenvironment Variation Mediated Targeting and Controlled Glioma Chemotherapy (Small 40/2016)

Sai An, Xiuhong Lu, Weili Zhao, Tao Sun, Yu Zhang, Yifei Lü, Chen Jiang

Small

DOI

2016

siRNA capsulated brain-targeted nanoparticles specifically knock down OATP2B1 in mice: a mechanism for acute morphine tolerance suppression

Zi-Zhao Yang, Li Li, Lu Wang, Ming-cheng Xu, Sai An, Chen Jiang, Jing-Kai Gu, Zai-Jie Jim Wang, Lu-Shan Yu, Su Zeng

Scientific Reports

DOI

2016

Amino Acid Metabolism Abnormity and Microenvironment Variation Mediated Targeting and Controlled Glioma Chemotherapy

Sai An, Xiuhong Lu, Weili Zhao, Tao Sun, Yu Zhang, Yifei Lü, Chen Jiang

Small

DOI

2016

T7 Peptide-Functionalized PEG-PLGA Micelles Loaded with Carmustine for Targeting Therapy of Glioma

Yunke Bi, Lisha Liu, Yifei Lü, Tao Sun, Chen Shen, Xinli Chen, Qinjun Chen, Sai An, Xi He, Chunhui Ruan, Yinhao Wu, Yujie Zhang, Qin Guo, Zhixing Zheng, Yaohua Liu, Meiqing Lou, Shiguang Zhao, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2016

Drug Delivery Strategies Based on Nanotechnology for Cancer Immunotherapy

Lisha Liu, Chen Jiang

Current Organic Chemistry

DOI

2016

Photo and redox-responsive vesicles assembled from Bola-type superamphiphiles

Tao Sun, Lan Shu, Jian Hong Shen, Chunhui Ruan, Zhifeng Zhao, Chen Jiang

RSC Advances

DOI

2016

ATP/pH Dual Responsive Nanoparticle with d ‐[des‐Arg10]Kallidin Mediated Efficient In Vivo Targeting Drug Delivery

Yu Zhang, Yifei Lü, Feng Wang, Sai An, Yujie Zhang, Tao Sun, Jianhua Zhu, Chen Jiang

Small

DOI

2016

Charge-reversal nanoparticles: novel targeted drug delivery carriers

Xinli Chen, Lisha Liu, Chen Jiang

Acta Pharmaceutica Sinica B

DOI

2016

Dual Functional Peptide-Driven Nanoparticles for Highly Efficient Glioma-Targeting and Drug Codelivery

Yuyang Kuang, Xutao Jiang, Yu Zhang, Yifei Lü, Haojun Ma, Yubo Guo, Yujie Zhang, Sai An, Jianfeng Li, Lisha Liu, Yinhao Wu, Jianying Liang, Chen Jiang

Molecular Pharmaceutics

DOI

2015

Choline Derivate-Modified Doxorubicin Loaded Micelle for Glioma Therapy

Jianfeng Li, Huiying Yang, Yujie Zhang, Xutao Jiang, Yubo Guo, Sai An, Haojun Ma, Xi He, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2015

Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency

Kaimin Cai, Xi He, Ziyuan Song, Qian Yin, Yanfeng Zhang, Fatih Mehmet Uckun, Chen Jiang, Jianjun Cheng

Journal of the American Chemical Society

DOI

2015

Linear–Dendritic Copolymer Composed of Polyethylene Glycol and All-trans-Retinoic Acid as Drug Delivery Platform for Paclitaxel against Breast Cancer

Jianfeng Li, Xutao Jiang, Yubo Guo, Sai An, Yuyang Kuang, Haojun Ma, Xi He, Chen Jiang

Bioconjugate Chemistry

DOI

2015

Brain-targeted co-delivery of therapeutic gene and peptide by multifunctional nanoparticles in Alzheimer's disease mice

Yang Liu, Sai An, Jianfeng Li, Yuyang Kuang, Xi He, Yubo Guo, Haojun Ma, Yu Zhang, Bin Ji, Chen Jiang

Biomaterials

DOI

2015

Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer

Hao Bing, Song Tian Gao, Jianfeng Li, Chen Jiang, Bo Hong

Drug Design Development and Therapy

DOI

2015

Development of chitosan nanoparticles as drug delivery system for a prototype capsid inhibitor

Meiyan Xue, Steven X. Hu, Yifei Lü, Yu Zhang, Xutao Jiang, Sai An, Yubo Guo, Xue Zhou, Huimin Hou, Chen Jiang

International Journal of Pharmaceutics

DOI

2015

Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer

Xiaolin Wang, Qingbing Wang, Jianfeng Li, Sai An, Yi Chen, Chen Jiang

International Journal of Nanomedicine

DOI

2015

Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy

Sai An, Xutao Jiang, Jiashu Shi, Xi He, Jianfeng Li, Yubo Guo, Yu Zhang, Haojun Ma, Yifei Lü, Chen Jiang

Biomaterials

DOI

2015

Cell Microenvironment-Controlled Antitumor Drug Releasing-Nanomicelles for GLUT1-Targeting Hepatocellular Carcinoma Therapy

Yubo Guo, Yujie Zhang, Jianfeng Li, Yu Xin Zhang, Yifei Lü, Xutao Jiang, Xi He, Haojun Ma, Sai An, Chen Jiang

ACS Applied Materials & Interfaces

DOI

2015

Reply to “The Brain, Amphotericin B, and P-Glycoprotein”

Jiqin Wu, Kun Shao, Chen Jiang, Liping Zhu

Antimicrobial Agents and Chemotherapy

DOI

2014

四乙酰芍药苷聚合物胶束的制备及其对大鼠脑缺血再灌注损伤的保护作用

张赟，安佃云，沈腾，王建新，蒋晨

《中国医药工业杂志》

2014

Functionalized Nanoscale Micelles with Brain Targeting Ability and Intercellular Microenvironment Biosensitivity for Anti‐Intracranial Infection Applications

Kun Shao, Yu Xin Zhang, Ning Ding, Shixian Huang, Jiqin Wu, Jianfeng Li, Chunfu Yang, Qibin Leng, Liya Ye, Jinning Lou, Liping Zhu, Chen Jiang

Advanced Healthcare Materials

DOI

2014

A Bacteria Deriving Peptide Modified Dendrigraft Poly- l -lysines (DGL) Self-Assembling Nanoplatform for Targeted Gene Delivery

Yang Liu, Xi He, Yuyang Kuang, Sai An, Chenyu Wang, Yubo Guo, Haojun Ma, Jinning Lou, Chen Jiang

Molecular Pharmaceutics

DOI

2014

In Vitro and In Vivo Evidence for Amphotericin B as a P-Glycoprotein Substrate on the Blood-Brain Barrier

Jiqin Wu, Kun Shao, Xuan Wang, Ruiying Wang, Yahui Cao, Yunqiu Yu, Jinning Lou, Yanqiong Chen, Hua‐Zhen Zhao, Qiang-Qiang Zhang, Xinhua Weng, Chen Jiang, Liping Zhu

Antimicrobial Agents and Chemotherapy

DOI

2014

Smart Nanodevice Combined Tumor-Specific Vector with Cellular Microenvironment-Triggered Property for Highly Effective Antiglioma Therapy

Kun Shao, Ning Ding, Shixian Huang, Sumei Ren, Yu Xin Zhang, Yuyang Kuang, Yubo Guo, Haojun Ma, Sai An, Yingxia Li, Chen Jiang

ACS Nano

DOI

2014

Tumor cell membrane-targeting pH-dependent electron donor-acceptor fluorescence systems with low background signals

Liang Han, Mingming Liu, Deyong Ye, Ning Zhang, Ed Lim, Jing Lu, Chen Jiang

Biomaterials

DOI

2013

纳米药物递释系统的脑靶向研究进展

刘洋，蒋晨

《药学学报》

2013

脑胶质瘤靶向药物递送系统

李剑峰，蒋晨

《国际药学研究杂志》

2013

Choline transporter-targeting and co-delivery system for glioma therapy

Jianfeng Li, Yubo Guo, Yuyang Kuang, Sai An, Haojun Ma, Chen Jiang

Biomaterials

DOI

2013

A choline derivate-modified nanoprobe for glioma diagnosis using MRI

Jianfeng Li, Shixian Huang, Kun Shao, Yang Liu, Sai An, Yuyang Kuang, Yubo Guo, Haojun Ma, Xuxia Wang, Chen Jiang

Scientific Reports

DOI

2013

pH-sensitive drug-delivery Systems for Tumor Targeting

Xi He, Jianfeng Li, Sai An, Chen Jiang

Therapeutic Delivery

DOI

2013

T7 peptide-functionalized nanoparticles utilizing RNA interference for glioma dual targeting

Yuyang Kuang, Sai An, Yubo Guo, Shixian Huang, Kun Shao, Yang Liu, Jianfeng Li, Haojun Ma, Chen Jiang

International Journal of Pharmaceutics

DOI

2013

Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson’s Disease

Yang Liu, Yubo Guo, Sai An, Yuyang Kuang, Xi He, Haojun Ma, Jianfeng Li, Jing Lv, Ning Zhang, Chen Jiang

PLoS ONE

DOI

2013

Acid Active Receptor‐Specific Peptide Ligand for In Vivo Tumor‐Targeted Delivery

Liang Han, Yubo Guo, Haojun Ma, Xi He, Yuyang Kuang, Ning Zhang, Ed Lim, Wenjiang Zhou, Chen Jiang

Small

DOI

2013

pH‐Controlled Delivery of Nanoparticles into Tumor Cells

Liang Han, Haojun Ma, Yubo Guo, Yuyang Kuang, Xi He, Chen Jiang

Advanced Healthcare Materials

DOI

2013

Tumor targeting and microenvironment-responsive nanoparticles for gene delivery

Shixian Huang, Kun Shao, Yuyang Kuang, Yang Liu, Jianfeng Li, Sai An, Yubo Guo, Haojun Ma, Xi He, Chen Jiang

Biomaterials

DOI

2013

Tumor-Targeting and Microenvironment-Responsive Smart Nanoparticles for Combination Therapy of Antiangiogenesis and Apoptosis

Shixian Huang, Kun Shao, Yang Liu, Yuyang Kuang, Jianfeng Li, Sai An, Yubo Guo, Haojun Ma, Chen Jiang

ACS Nano

DOI

2012

Targeted imaging of activated caspase-3 in the central nervous system by a dual functional nano-device

Yang Liu, Yuzhi Hu, Yubo Guo, Haojun Ma, Jianfeng Li, Chen Jiang

Journal of Controlled Release

DOI

2012

A brain-vectored angiopep-2 based polymeric micelles for the treatment of intracranial fungal infection

Kun Shao, Jiqin Wu, Zhongqing Chen, Shixian Huang, Jianfeng Li, Liya Ye, Jinning Lou, Liping Zhu, Chen Jiang

Biomaterials

DOI

2012

Gene and doxorubicin co-delivery system for targeting therapy of glioma

Shuhuan Liu, Yubo Guo, Rongqin Huang, Jianfeng Li, Shixian Huang, Yuyang Kuang, Liang Han, Chen Jiang

Biomaterials

DOI

2011

诊断兼治疗的多功能肿瘤靶向纳米递释系统

韩亮，黄容琴，蒋晨

《国际药学研究杂志》

2011

Choline‐Derivate‐Modified Nanoparticles for Brain‐Targeting Gene Delivery

Jianfeng Li, Lu Zhou, Deyong Ye, Shixian Huang, Kun Shao, Rongqin Huang, Liang Han, Yang Liu, Shuhuan Liu, Liya Ye, Jinning Lou, Chen Jiang

Advanced Materials

DOI

2011

Chlorotoxin-modified macromolecular contrast agent for MRI tumor diagnosis

Rongqin Huang, Liang Han, Jianfeng Li, Shuhuan Liu, Kun Shao, Yuyang Kuang, Xing Hu, Xuxia Wang, Hao Chuan Lei, Chen Jiang

Biomaterials

DOI

2011

Peptide-conjugated polyamidoamine dendrimer as a nanoscale tumor-targeted T1 magnetic resonance imaging contrast agent

Liang Han, Jianfeng Li, Shixian Huang, Rongqin Huang, Shuhuan Liu, Xing Hu, Peiwei Yi, Dai Shan, Xuxia Wang, Hao Chuan Lei, Chen Jiang

Biomaterials

DOI

2010

脑靶向非病毒基因递释系统的研究进展

黄容琴，柯伟伦，蒋晨，裴元英

《国际药学研究杂志》

2010

Targeted delivery of chlorotoxin-modified DNA-loaded nanoparticles to glioma via intravenous administration

Rongqin Huang, Weilun Ke, Liang Han, Jianfeng Li, Shuhuan Liu, Chen Jiang

Biomaterials

DOI

2010

Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer

Liang Han, Rongqin Huang, Jianfeng Li, Shuhuan Liu, Shixian Huang, Chen Jiang

Biomaterials

DOI

2010

Peptide-Conjugated PAMAM for Targeted Doxorubicin Delivery to Transferrin Receptor Overexpressed Tumors

Liang Han, Rongqin Huang, Shuhuan Liu, Shixian Huang, Chen Jiang

Molecular Pharmaceutics

DOI

2010

Angiopep-2 modified PE-PEG based polymeric micelles for amphotericin B delivery targeted to the brain

Kun Shao, Rongqin Huang, Jianfeng Li, Liang Han, Liya Ye, Jinning Lou, Chen Jiang

Journal of Controlled Release

DOI

2009

Lactoferrin-modified nanoparticles could mediate efficient gene delivery to the brain in vivo

Rongqin Huang, Weilun Ke, Liang Han, Yang Liu, Kun Shao, Chen Jiang, Yuanying Pei

Brain Research Bulletin

DOI

2009

Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model

Rongqin Huang, Weilun Ke, Yang Liu, Dongdong Wu, Linyin Feng, Chen Jiang, Yuanying Pei

Journal of the Neurological Sciences

DOI

2009

Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer

Weilun Ke, Kun Shao, Rongqin Huang, Liang Han, Yang Liu, Jianfeng Li, Yuyang Kuang, Liya Ye, Jinning Lou, Chen Jiang

Biomaterials

DOI

2009

Brain-targeting gene delivery and cellular internalization mechanisms for modified rabies virus glycoprotein RVG29 nanoparticles

Yang Liu, Rongqin Huang, Liang Han, Weilun Ke, Kun Shao, Liya Ye, Jinning Lou, Chen Jiang

Biomaterials

DOI

2007

The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain

Rongqin Huang, Weilun Ke, Yang Liu, Chen Jiang, Yuanying Pei

Biomaterials

DOI

2007

Enhanced Oral Bioavailability of Doxorubicin in a Dendrimer Drug Delivery System

Weilun Ke, Yansong Zhao, Rongqin Huang, Chen Jiang, Yuanying Pei

Journal of Pharmaceutical Sciences

DOI

2007

Enhanced gene transfer into brain capillary endothelial cells using Antp-modified DNA-loaded nanoparticles

Rongqin Huang, Yuanying Pei, Chen Jiang

Journal of Biomedical Science

DOI

2007

Efficient gene delivery targeted to the brain using a transferrin‐conjugated polyethyleneglycol‐modified polyamidoamine dendrimer

Rongqin Huang, Yinghua Qu, Weilun Ke, Jianhua Zhu, Yuanying Pei, Chen Jiang

The FASEB Journal

DOI

精选作品

期刊论文

AI‐Optimized 3D‐Printed Dual‐Layer Implant: Resolving Chemo‐Immunotherapy Sequential Administration Dilemma for Colorectal Cancer Peritoneal Metastasis

Shutting Down the ‘Language Encoder’: A Pathogen‐Derived Nano‐Interferer Disrupt Sialylation Metabolism and Reprogram Intercellular Communication in Glioblastoma

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

Intravenous Multifunctional Nanotherapy for Treating Dry Age‐Related Macular Degeneration

Mitocytosis-inducing nanoparticles alleviate gemcitabine resistance via dual disruption of pyrimidine synthesis and redox homeostasis in pancreatic ductal adenocarcinoma

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

NIR-II Luminescent Nanothermometer for Precise Assessment of Ischemic Stroke

Multiple‐Stimuli‐Responsive Biomimetic Polypyrrole Delivery System for Synergistic Regulation and Restoration of Epileptic Foci

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Disrupting Tumor Lactate Homeostasis to Sensitize Chemo-Immunotherapy Using a Glucose-Disguised Lactate Interceptor

Manganese-based virus-mimicking nanomedicine with triple immunomodulatory functions inhibits breast cancer brain metastasis

Engineered Intelligent Microenvironment Responsive Prodrug Conjugates Navigated by Bioinspired Lipoproteins for Reversing Liver Fibrosis

PROTAC-loaded nanocapsules degrading BRD4 for radio-chemotherapy sensitization in glioblastoma

Transcytosis-Triggering Nanoparticles for Overcoming Stromal Barriers and Reversing Immunosuppression in Pancreatic Cancer Combinatorial Therapy

Polymer-engineered PROTAC nanovehicles amplify synergistic effects with temozolomide by BRD4 degradation

Metabolic Nanoregulators Induce Ferroptosis and Change Metabolite Flow to Reverse Immunosuppressive Tumor Microenvironment

PROTAC delivery in tumor immunotherapy: Where are we and where are we going?

Size and Charge Dual‐Switchable Nanoparticles for Achieving Chemosensitization and Immune Infiltration against Pancreatic Ductal Adenocarcinoma

Cabozantinib-encapsulated and maytansine-conjugated high-density lipoprotein for immunotherapy in colorectal cancer

A Peptide‐Drug Conjugate‐Based Nanoplatform for Immunometabolic Activation and In Situ Nerve Regeneration in Advanced‐Stage Alzheimer's Disease

Intelligent micelles for on-demand drug delivery targeting extracellular matrix of pancreatic cancer

Recent advances in biomimetic strategies for the immunotherapy of glioblastoma

Reconciling the Cooperative–Competitive Patterns among Tumor and Immune Cells for Triple‐Negative Breast Cancer Treatment Using Multimodule Nanocomplexes

Therapeutic regulation of epigenetics in cancer treatment through drug delivery systems

Intelligent Delivery Systems in Tumor Metabolism Regulation: Exploring the Path Ahead

Nanomaterials for brain metastasis

Pleiotropic Microenvironment Remodeling Micelles for Cerebral Ischemia-Reperfusion Injury Therapy by Inhibiting Neuronal Ferroptosis and Glial Overactivation

Gradient tumor microenvironment-promoted penetrating micelles for hypoxia relief and immunosuppression reversion in pancreatic cancer treatment

Nanomaterials with dual immunomodulatory functions for synergistic therapy of breast cancer brain metastases

ROS/Electro Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberrant Circuits and Inflammatory Microenvironment

Transcytosis Mediated Deep Tumor Penetration for Enhanced Chemotherapy and Immune Activation of Pancreatic Cancer

Stimuli-responsive drug delivery systems triggered by intracellular or subcellular microenvironments

Bioinspired nanoerythrocytes for metabolic microenvironment remodeling and long-term prognosis promoting of acute ischemic stroke

Compound Nanoemulsion Combined with Differentiation/Cytotoxicity Drugs for Modulating Breast Cancer Stemness

纳米仿生型肿瘤疫苗的研究进展

载奥沙利铂的还原敏感型四氧化三铁纳米粒的体内外靶向性评价

Microenvironment-tailored micelles restrain carcinoma-astrocyte crosstalk for brain metastasis

Extracellular vesicle-based macromolecule delivery systems in cancer immunotherapy

Transformable “Tubulin Traps” Interfere with Mitochondrial Autophagy and Promote the Elimination of Glioblastoma

ROS-removing nano-medicine for navigating inflammatory microenvironment to enhance anti-epileptic therapy

A Triple Therapeutic Strategy with Antiexosomal Iron Efflux for Enhanced Ferroptosis Therapy and Immunotherapy

A neutrophil-biomimic platform for eradicating metastatic breast cancer stem-like cells by redox microenvironment modulation and hypoxia-triggered differentiation therapy

Smart hypoxia-responsive transformable and charge-reversible nanoparticles for the deep penetration and tumor microenvironment modulation of pancreatic cancer

Brain‐targeting drug delivery systems

Penetrating Micelle for Reversing Immunosuppression and Drug Resistance in Pancreatic Cancer Treatment

Emerging landscapes of nanosystems based on pre-metastatic microenvironment for cancer theranostics

Physicochemical Characterization and Pharmacological Evaluation of Novel Propofol Micelles with Low-Lipid and Low-Free Propofol

Exosomes derived from immunogenically dying tumor cells as a versatile tool for vaccination against pancreatic cancer

A Micro‐Environment Regulator for Filling the Clinical Treatment Gap after a Glioblastoma Operation

Intravenous route to choroidal neovascularization by macrophage-disguised nanocarriers for mTOR modulation

Macrophage‐Disguised Manganese Dioxide Nanoparticles for Neuroprotection by Reducing Oxidative Stress and Modulating Inflammatory Microenvironment in Acute Ischemic Stroke

A Versatile Theranostic Platform for Colorectal Cancer Peritoneal Metastases: Real‐Time Tumor‐Tracking and Photothermal‐Enhanced Chemotherapy

Sequentially Triggered Bacterial Outer Membrane Vesicles for Macrophage Metabolism Modulation and Tumor Metastasis Suppression

Biomimetic Dendrimer–Peptide Conjugates for Early Multi‐Target Therapy of Alzheimer's Disease by Inflammatory Microenvironment Modulation

Recent advances on drug delivery nanocarriers for cerebral disorders

Postoperative cancer treatments: In-situ delivery system designed on demand

NIR-Light-Intensified Hypoxic Microenvironment for Cascaded Supra-Prodrug Activation and Synergistic Chemo/Photodynamic Cancer Therapy

Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies

Click-Nucleic-Acid-Containing Codelivery System Inducing Collapse of Cellular Homeostasis for Tumor Therapy through Bidirectional Regulation of Autophagy and Glycolysis

Recent advances in nanomedicines for the treatment of ischemic stroke

Penetrable Nanoplatform for “Cold” Tumor Immune Microenvironment Reeducation

Carry-On Nitric-Oxide Luggage for Enhanced Chemotherapeutic Efficacy

Supramolecular Hunter Stationed on Red Blood Cells for Detoxification Based on Specific Molecular Recognition

Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic

Theranostic nanoparticles enabling the release of phosphorylated gemcitabine for advanced pancreatic cancer therapy

Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment

Delivery strategies for macromolecular drugs in cancer therapy

Dynamic covalent chemistry-regulated stimuli-activatable drug delivery systems for improved cancer therapy

Dandelion‐Like Tailorable Nanoparticles for Tumor Microenvironment Modulation

Nano-engineered lymphocytes for alleviating suppressive tumor immune microenvironment

Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein

Codelivery Nanosystem Targeting the Deep Microenvironment of Pancreatic Cancer

Microthrombus‐Targeting Micelles for Neurovascular Remodeling and Enhanced Microcirculatory Perfusion in Acute Ischemic Stroke

Drug Delivery: Activated Platelets‐Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer (Adv. Funct. Mater. 13/2019)

Pre-blocked molecular shuttle as an in-situ real-time theranostics

Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)

Tumor Microenvironment‐Triggered Aggregated Magnetic Nanoparticles for Reinforced Image‐Guided Immunogenic Chemotherapy