李云晖｜东南大学｜学者主页

2026

Simultaneously PYCR-1 and ALH-6 inhibition exacerbates 6-PPD quinone toxicity via disrupting proline and glutamate metabolisms and activating insulin signals in Caenorhabditis elegans.

Wei Wang, Yunhui Li, Da-Yong Wang

Journal of Environmental Science

DOI

2026

Activation of Thiamine Pyrophosphokinase TPK-1 Contributes to 6-PPD Quinone-Induced Immunosuppression by Inhibiting Mitochondrial UPR in Caenorhabditis elegans

Zhe Wu, Guocheng Hu, Yunhui Li, Da-Yong Wang

Toxics

DOI

2026

Inhibition in β-hydroxybutyrate synthesis by 6-PPD quinone at environmentally relevant concentrations is associated with immunosuppression induction in Caenorhabditis elegans

Wei Wang, Zhe Wu, Yunhui Li, Dayong Wang

Aquatic Toxicology

DOI

2025

Exposure to 6-PPD Quinone Disrupts Adsorption and Catabolism of Leucine and Causes Mitochondrial Dysfunction in Caenorhabditis elegans

Wei Wang, Yunhui Li, Da-Yong Wang

Toxics

DOI

2025

Photo-aged polylactic acid microplastics causes severe transgenerational decline in reproductive capacity in C. elegans: Insight into activation of DNA damage checkpoints affected by multiple germline histone methyltransferases.

Jingwei Wu, Yuting Shao, Xin Hua, Yunhui Li, Da-Yong Wang

Environmental Pollution

DOI

2025

Long-Term Exposure to 6-PPD Quinone Inhibits Glutamate Synthesis and Glutamate Receptor Function Associated with Its Toxicity Induction in Caenorhabditis elegans

Wei Wang, Yunhui Li, Da-Yong Wang

Toxics

DOI

2024

Comparison of reproductive toxicity between pristine and aged polylactic acid microplastics in Caenorhabditis elegans.

Yuting Shao, Xin Hua, Yunhui Li, Da-Yong Wang

Journal of Hazardous Materials

DOI

2024

Polylactic acid microplastics cause transgenerational reproductive toxicity associated with activation of insulin and hedgehog ligands in C. elegans.

Yuting Shao, Yunhui Li, Da-Yong Wang

Science of the Total Environment

DOI

2024

Transgenerational response of glucose metabolism in Caenorhabditis elegans exposed to 6-PPD quinone.

Zhenjun Liu, Yunhui Li, Da-Yong Wang

Chemosphere

DOI

2024

Exposure to 6-PPD quinone disrupted glucose metabolism associated with lifespan reduction by affecting insulin and AMPK signals in Caenorhabditis elegans.

Zhenjun Liu, Yunhui Li, Da-Yong Wang

Chemosphere

DOI

2023

Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans

Yuting Shao, Yuxing Wang, Xin Hua, Yunhui Li, Dayong Wang

Chemosphere

DOI

2022

BTBD9 attenuates manganese-induced oxidative stress and neurotoxicity by regulating insulin growth factor signaling pathway

Pan Chen, Hong Cheng, Fuli Zheng, Shaojun Li, Julia Bornhorst, Bobo Yang, Kun He Lee, Tao Ke, Yunhui Li, Tanja Schwerdtle, Xiaobo Yang, Aaron B. Bowman, Michael Aschner

Human Molecular Genetics

DOI

2021

环境类课程思政设计探索——以“人类与环境”课程为例

孙蓉丽，李云晖，刘冉，梁戈玉，张娟

《教育教学论坛》

2020

Effect of chronic exposure to nanopolystyrene on nematode Caenorhabditis elegans

Yuexiu Qiu, Yaqi Liu, Yunhui Li, Guojun Li, Dayong Wang

Chemosphere

DOI

2019

浅析中美两国环境卫生学课程设置的差异

李云晖，刘冉，梁戈玉，沈孝兵，尹立红，金辉

《中国高等医学教育》

2019

邻苯二甲酸二(2-乙基己基)酯对秀丽线虫生殖能力的影响

岳营，李晶晶，屈满，邱月秀，刘冉，尹立红，李云晖

《癌变·畸变·突变》

2019

Identification and characterization of a novel indigenous algicidal bacterium Chryseobacterium species against Microcystis aeruginosa

Chengcheng Zhang, Isaac Yaw Massey, Yan Liu, Feiyu Huang, Ruihuan Gao, Ming Ding, Lin Xiang, Chuning He, Wei Ping Jia, Yunhui Li, Yuliang Ge, Fei Yang

Journal of Toxicology and Environmental Health

DOI

2018

戊唑醇对秀丽线虫的生殖毒性作用

吕荣荣，屈满，岳营，邱月秀，尹立红，李云晖

《癌变·畸变·突变》

2018

Removal of Microcystin-LR by a Novel Native Effective Bacterial Community Designated as YFMCD4 Isolated from Lake Taihu

Fei Yang, Jian Guo, Feiyu Huang, Isaac Yaw Massey, Ruixue Huang, Yunhui Li, Cong Wen, Ping Ding, Weiming Zeng, Geyu Liang

Toxins

DOI

2018

Using acs-22 mutant Caenorhabditis elegans to detect the toxicity of nanopolystyrene particles

Man Qu, Kangni Xu, Yunhui Li, Garry Wong, Dayong Wang

The Science of The Total Environment

DOI

2017

全氟辛烷磺酸对雄性秀丽隐杆线虫的生殖毒性

徐弘昕，简子海，李云晖

《世界最新医学信息文摘》

2016

The Use of the Nematode Caenorhabditis elegans to Evaluate the Adverse Effects of Epoxiconazole Exposure on Spermatogenesis

Yunhui Li, Min-hui Zhang, Shaojun Li, Rongrong Lv, Pan Chen, Ran Liu, Geyu Liang, Lihong Yin

International Journal of Environmental Research and Public Health

DOI

2015

微囊藻毒素-LR对大鼠海马组织中N-乙酰门冬氨酸及神经行为的作用（英文）

李云晖，周珏，张敏辉，杨明，李晓波，刘冉，尹立红，浦跃朴

Journal of Southeast University(English Edition)

2015

微囊藻毒素-LR所致神经小胶质细胞BV-2的炎性反应

张敏辉，周珏，刘冉，李晓波，梁戈玉，李云晖

《癌变·畸变·突变》

2015

Effects of Microcystin-LR Exposure on Spermiogenesis in Nematode Caenorhabditis elegans

Yunhui Li, Min-hui Zhang, Pan Chen, Ran Liu, Geyu Liang, Lihong Yin, Yuepu Pu

International Journal of Molecular Sciences

DOI

2015

Caenorhabditis elegans as a useful model to assess the effect of spermiogenesis induced by three teratogens

Yunhui Li, Min-hui Zhang, Xiaobo Li, Juan Zhang, Ran Liu, Geyu Liang, Yuepu Pu, Lihong Yin

Molecular & Cellular Toxicology

DOI

2014

微囊藻毒素-LR对秀丽线虫精子形成的毒性作用

杨菲飞，张敏辉，尹立红，李云晖

《癌变·畸变·突变》

2013

微囊藻毒素-LR对大鼠行为认知能力及血脑屏障通透性的影响

李洋，周珏，孙冰，李雪珂，李云晖

《东南大学学报(医学版)》

2013

Biodegradation of microcystin-LR and-RR by a novel microcystin-degrading bacterium isolated from Lake Taihu

Fei Yang, Yuanlong Zhou, Rongli Sun, Haiyan Wei, Yunhui Li, Lihong Yin, Yuepu Pu

Biodegradation

DOI

2012

2007～2010年无锡市滨湖区游泳池水质监测分析

黄文光，倪敏华，邵瑜，李云晖

《现代预防医学》

2012

微囊藻毒素-LR对PC12细胞氧化性损伤作用的实验研究

周珏，刘冉，李晓波，杨菲飞，李云晖

《癌变·畸变·突变》

2012

氯氰菊酯对模式动物秀丽隐杆线虫生殖能力的损伤作用

阮秦莉，居静娟，李云晖，李晓波，刘冉，梁戈玉，张娟，浦跃朴，尹立红，王大勇

《癌变·畸变·突变》

2012

Lysing activity of an indigenous algicidal bacteriumAeromonassp. againstMicrocystisspp. isolated from Lake Taihu

Fei Yang, Xiaoqin Li, Yunhui Li, Hai‐Yan Wei, Guang Yu, Lihong Yin, Geyu Liang, Yuepu Pu

Environmental Technology

DOI

2010

太湖水华藻的分离、鉴定和产毒特性

李小琴，杨飞，尹立红，梁戈玉，李云晖，浦跃朴

《东南大学学报(自然科学版)》

2009

超声除藻的参数优化及其在太湖除藻中的应用

丁暘，浦跃朴，尹立红，邱潇潇，李云晖，吴巍

《东南大学学报(自然科学版)》

2009

Evaluation of Pesticide Toxicities with Differing Mechanisms UsingCaenorhabditis elegans

Qinli Ruan, Jing‐Juan Ju, Yunhui Li, Ran Liu, Yuepu Pu, Lihong Yin, Dayong Wang

Journal of Toxicology and Environmental Health

DOI

2008

组合介质中太湖土著溶藻菌的优势度分析

李云晖，刘冉，浦跃朴，于光，尹立红，吕锡武

《环境与职业医学》

2008

聚己内酯纳米纤维膜固定化溶藻菌对藻类和藻毒素的生物降解作用

于光，李云晖，姚琛，尹立红，李新松，浦跃朴

《东南大学学报(自然科学版)》

2007

浅析医学Powerpoint电子教案授课中存在的几个误区

尹立红，浦跃朴，李云晖，梁戈玉

《卫生职业教育》

2006

以精品课程建设为契机,强化《环境卫生学》实验课程教学

李云晖，尹立红，浦跃朴，梁戈玉，张晖，沈孝兵

《东南大学学报(医学版)》

2006

环境卫生学设计性实验教学探索

张晖，尹立红，浦跃朴，沈孝彬，李云晖，梁戈玉

《中华医学教育探索杂志》

2003

对苯二胺氧化产物的细胞恶性转化研究

袁慧，浦跃朴，尹立红，李云晖

《环境与健康杂志》

2002

煤烟对大鼠肺细胞氧化性损伤作用途径的探讨

李云晖，浦跃朴，尹立红，张荣泉

《环境与健康杂志》

2002

对苯二胺氧化产物对小鼠经皮肤染毒的亚慢性毒性

袁慧，浦跃朴，尹立红，李云晖

《环境与职业医学》

2001

煤烟颗粒提取物对大鼠肺细胞的氧化性损伤作用

李云晖，浦跃朴，尹立红，仲伟鉴，张荣泉

《中国公共卫生》

2001

氧化型染发剂对大鼠皮肤角朊细胞毒作用的实验研究

吕冬梅，浦跃朴，尹立红，李云晖，戴修道，杨薇，周德灏

《环境与健康杂志》

2001

煤烟导致非细胞体系DNA氧化应激损伤的机制

李云晖，浦跃朴，仲伟鉴

《环境与职业医学》

2000

氧化型染发剂主要成分对皮肤细胞DNA、脂质和蛋白质合成能力的影响

吕冬梅，浦跃朴，尹立红，李云晖，戴修道，杨薇，周德灏

《东南大学学报(医学版)》

2000

氧化型染发剂主要成分对大鼠皮肤角朊细胞DNA损伤作用的研究

吕冬梅，浦跃朴，尹立红，李云晖，戴修道，杨薇，周德灏

《中国公共卫生》

1999

氧化型染发剂遗传毒性作用的实验研究

吕冬梅，浦跃朴，尹立红，李云晖，杨薇，戴修道，周德灏

《环境与健康杂志》

1999

烹调油烟颗粒有机提取物对大鼠肺Ⅱ型细胞周期的影响

尹立红，浦跃朴，李云晖，吕冬梅，印木泉

《环境与健康杂志》

1999

铁路危险品货运站空气污染指标的探讨

张徐军，浦跃朴，卢玉川，尹立红，李云晖，吕冬梅

《环境与健康杂志》

1999

铁路危险品货运站空气污染物的致遗传毒性作用研究

张徐军，浦跃朴，李云晖，吕冬梅，卢玉川

《中国公共卫生学报》

1998

煤烟颗粒提取物致大鼠肺细胞DNA交联作用的研究

李云晖，浦跃朴，尹立红，吕冬梅，仲伟鉴，肖萍，董妙珠，张荣泉

《东南大学学报(医学版)》

精选作品

期刊论文

Simultaneously PYCR-1 and ALH-6 inhibition exacerbates 6-PPD quinone toxicity via disrupting proline and glutamate metabolisms and activating insulin signals in Caenorhabditis elegans.

Activation of Thiamine Pyrophosphokinase TPK-1 Contributes to 6-PPD Quinone-Induced Immunosuppression by Inhibiting Mitochondrial UPR in Caenorhabditis elegans

Inhibition in β-hydroxybutyrate synthesis by 6-PPD quinone at environmentally relevant concentrations is associated with immunosuppression induction in Caenorhabditis elegans

Exposure to 6-PPD Quinone Disrupts Adsorption and Catabolism of Leucine and Causes Mitochondrial Dysfunction in Caenorhabditis elegans

Photo-aged polylactic acid microplastics causes severe transgenerational decline in reproductive capacity in C. elegans: Insight into activation of DNA damage checkpoints affected by multiple germline histone methyltransferases.

Long-Term Exposure to 6-PPD Quinone Inhibits Glutamate Synthesis and Glutamate Receptor Function Associated with Its Toxicity Induction in Caenorhabditis elegans

Comparison of reproductive toxicity between pristine and aged polylactic acid microplastics in Caenorhabditis elegans.

Polylactic acid microplastics cause transgenerational reproductive toxicity associated with activation of insulin and hedgehog ligands in C. elegans.

Transgenerational response of glucose metabolism in Caenorhabditis elegans exposed to 6-PPD quinone.

Exposure to 6-PPD quinone disrupted glucose metabolism associated with lifespan reduction by affecting insulin and AMPK signals in Caenorhabditis elegans.

Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans

BTBD9 attenuates manganese-induced oxidative stress and neurotoxicity by regulating insulin growth factor signaling pathway

环境类课程思政设计探索——以“人类与环境”课程为例

Effect of chronic exposure to nanopolystyrene on nematode Caenorhabditis elegans

浅析中美两国环境卫生学课程设置的差异

邻苯二甲酸二(2-乙基己基)酯对秀丽线虫生殖能力的影响

Identification and characterization of a novel indigenous algicidal bacterium Chryseobacterium species against Microcystis aeruginosa

戊唑醇对秀丽线虫的生殖毒性作用

Removal of Microcystin-LR by a Novel Native Effective Bacterial Community Designated as YFMCD4 Isolated from Lake Taihu

Using acs-22 mutant Caenorhabditis elegans to detect the toxicity of nanopolystyrene particles

全氟辛烷磺酸对雄性秀丽隐杆线虫的生殖毒性

The Use of the Nematode Caenorhabditis elegans to Evaluate the Adverse Effects of Epoxiconazole Exposure on Spermatogenesis

微囊藻毒素-LR对大鼠海马组织中N-乙酰门冬氨酸及神经行为的作用（英文）

微囊藻毒素-LR所致神经小胶质细胞BV-2的炎性反应

Effects of Microcystin-LR Exposure on Spermiogenesis in Nematode Caenorhabditis elegans

Caenorhabditis elegans as a useful model to assess the effect of spermiogenesis induced by three teratogens

微囊藻毒素-LR对秀丽线虫精子形成的毒性作用

微囊藻毒素-LR对大鼠行为认知能力及血脑屏障通透性的影响

Biodegradation of microcystin-LR and-RR by a novel microcystin-degrading bacterium isolated from Lake Taihu

2007～2010年无锡市滨湖区游泳池水质监测分析

微囊藻毒素-LR对PC12细胞氧化性损伤作用的实验研究

氯氰菊酯对模式动物秀丽隐杆线虫生殖能力的损伤作用

Lysing activity of an indigenous algicidal bacteriumAeromonassp. againstMicrocystisspp. isolated from Lake Taihu

太湖水华藻的分离、鉴定和产毒特性

超声除藻的参数优化及其在太湖除藻中的应用

Evaluation of Pesticide Toxicities with Differing Mechanisms UsingCaenorhabditis elegans

组合介质中太湖土著溶藻菌的优势度分析

聚己内酯纳米纤维膜固定化溶藻菌对藻类和藻毒素的生物降解作用

浅析医学Powerpoint电子教案授课中存在的几个误区

以精品课程建设为契机,强化《环境卫生学》实验课程教学

环境卫生学设计性实验教学探索

对苯二胺氧化产物的细胞恶性转化研究

煤烟对大鼠肺细胞氧化性损伤作用途径的探讨

对苯二胺氧化产物对小鼠经皮肤染毒的亚慢性毒性

煤烟颗粒提取物对大鼠肺细胞的氧化性损伤作用

氧化型染发剂对大鼠皮肤角朊细胞毒作用的实验研究

煤烟导致非细胞体系DNA氧化应激损伤的机制

氧化型染发剂主要成分对皮肤细胞DNA、脂质和蛋白质合成能力的影响

氧化型染发剂主要成分对大鼠皮肤角朊细胞DNA损伤作用的研究

氧化型染发剂遗传毒性作用的实验研究

烹调油烟颗粒有机提取物对大鼠肺Ⅱ型细胞周期的影响

铁路危险品货运站空气污染指标的探讨

铁路危险品货运站空气污染物的致遗传毒性作用研究

煤烟颗粒提取物致大鼠肺细胞DNA交联作用的研究

会议论文

纳米聚苯乙烯和微囊藻毒素联合暴露致秀丽线虫毒性机制的研究

微囊藻毒素LR对大鼠神经行为毒性作用机制初探

构建汉族永生化淋巴细胞库研究苯、甲醛关键代谢酶功能SNPs

预印本

BTBD9 is a novel component of IGF signaling and regulates manganese-induced dopaminergic dysfunction

研究方向