百晓学者学者目录

张朝

研究员，复旦大学

精选作品

期刊论文

2026

Determinants of rapid antiretroviral therapy initiation and its longitudinal clinical outcomes among people living with HIV in China: a single-center retrospective cohort study

Yong-Bing Sun, Bing Song, Juan Cheng, Chao Zhang, Cheng Zhen, Rong-Jiao Liang, Xin-Yi Yang, Zhuang-Hong Zhao, Tian-Jun Jiang

BMC Infectious Diseases

DOI

2026

Impaired non-spike-specific Th1 CD4+ T cell responses to inactivated SARS-CoV-2 vaccines and Omicron breakthrough infection in older individuals who had recovered from COVID-19

Xing Fan, Jia-He Tian, Bo Zhang, Jing Wang, Qian-Xia Guo, Nan Guo, Xia Li, Guan-Zhen Wang, Ming-Ju Zhou, Jin-Wen Song, Le Song, Qiong Mo, W. Ni, Xun-Cheng Li, Li-Li Zhou, Xiu-Qing Xu, Chao Zhang, Fu-Sheng Wang, Lei Huang

Journal of Translational Medicine

DOI

2026

Distinct Innate and Adaptive Immune Modules Differentially Associate with HIV Reservoir Size and Decay During Early Antiretroviral Therapy

Wei-Zhe Li, Huihuang Huang, Hui-Fang Wang, Xia Li, Ming-Ju Zhou, Yuxuan Yang, You Wang, Meng-Meng Zhu, Ying Sun, Si-Yuan Chen, Xing Fan, Yan-Mei Jiao, Jin-Wen Song, Ruo-Nan Xu, Cheng Zhen, M. Shi, Chao Zhang, Fu-Sheng Wang

Cells

DOI

2026

A preS2 aa1–26-specific humoural response marks functional cure in chronic HBV infection

You Wang, Jun-Liang Fu, Wen-Xin Wang, Hongmei Wang, Shan-Quan Liu, Ying Sun, Ziwei Wang, Jing Li, Ming-Ju Zhou, Wei-Zhe Li, Mengmeng Zhu, Xia Li, Yuxuan Yang, Si-Yuan Chen, Tao Yang, Xing Fan, Ruo-Nan Xu, Yan-Mei Jiao, Jin-Wen Song, Cheng Zhen, Min Zhang, M. Shi, Fu-Sheng Wang, Chao Zhang

EBioMedicine

DOI

2026

Influencing factors of prognosis in HIV infected individuals undergoing surgical treatment for colorectal cancer

Xia Li, Chao Zhang, Guanzheng Wang, Min-Hong Mou, Meng-Meng Zhu, Qian-qian Guo, Yuxuan Yang, Ruyi Tian, Jian-Ning Deng, Lei Huang

Frontiers in Oncology

DOI

2026

High Frequency of Circulating IL-4R+SELL+ Naïve B Cells Is Associated with Functional Cure in Chronic Hepatitis B Patients Receiving Antiviral Treatment

Li-Li Tang, Chun-Mei Bao, Cheng Zhen, Huan Wang, Chao Zhang, Yang Zhang, Hong-Hong Liu, Jin-Wen Song, Yan-Mei Jiao, Tao Yang, Yue Yuan, Jin-Hong Yuan, Ying-Ying Gao, Yang Chen, Lin Cao, Jing Li, Jun-Liang Fu, Furang Wang, Ruo-Nan Xu

Journal of Clinical and Translational Hepatology

DOI

2026

Single-cell sequencing reveals NK cell dysregulation during chronic HIV infection and identifies transitional NK cell cytotoxicity related to HIV reservoir decay

Wen-Jing Cao, Baopeng Yang, Si-Yuan Chen, Cheng Zhen, Xuemiao Li, Xiang-Yi Cao, Lin-Yu Wan, Li-Ping Zhang, Mengyuan Zhang, Jia-Min Gao, Chao Zhang, Yan-Mei Jiao, Xing Fan, Ruo-Nan Xu, Huihuang Huang, Fu-Sheng Wang, Jin-Wen Song

EBioMedicine

DOI

2026

Sequential combination of anti-PD-1 antibody and PEG-IFNα in chronic hepatitis B patients: correlates of HBsAg loss with enhanced T-cell responses

Hong-Min Wang, Chao Zhang, Xiao-Ying Li, Ya-Ping Li, Xin Zhang, Ruo-Nan Xu, Kai-Li Wang, Sa Lv, Xing Fan, Qing Wang, Shan-Quan Liu, Sheng-Xian Yang, Xiao-Ning Zhang, Shuang-Suo Dang, Furang Wang, Jun-Liang Fu

Emerging Microbes and Infections

DOI

2025

Dose-escalation studies of mesenchymal stromal cell therapy for decompensated liver cirrhosis: phase Ia/Ib results and immune modulation insights

Lei Shi, Zi-Ying Zhang, Song Mei, Zerui Wang, Zhe Xu, Wei-Qi Yao, Liming Liu, Meng-Qi Yuan, Yuefei Pan, Kai-Di Zhu, Kai Liu, Fang-Lin Meng, Jiao Sun, Wen-Ying Liu, Xiao-yan Xie, T. Dong, Lei Huang, Fan-Ping Meng, Jun-Liang Fu, Yuan-Yuan Li, Chao Zhang, Xing Fan, M. Shi, Yu Zhang, Yong-Gang Li, Wei-Fen Xie, Peng Zhang, Fu-Sheng Wang

Signal Transduction and Targeted Therapy

DOI

2025

Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1

Lin-Yu Wan, Sin-Man Lam, Huihuang Huang, Wen-Jing Cao, Xiang-Yi Cao, Xuemiao Li, Li-Ping Zhang, Jia-Min Gao, Chao Zhang, Xing Fan, Yan-Mei Jiao, Guang-Hou Shui, Fu-Sheng Wang, Jin-Wen Song

Journal of Translational Medicine

DOI

2025

Safety and efficacy of human umbilical cord-derived mesenchymal stem cells in COVID-19 patients: A real-world observation

Siyu Wang, Tao Yang, Tiantian Li, Lei Shi, Ruo-Nan Xu, Chao Zhang, Zerui Wang, Zi-Ying Zhang, M. Shi, Zhe Xu, Fu-Sheng Wang

Chinese Medical Journal

DOI

2025

Long-term outcomes of mesenchymal stem cell therapy in severe COVID-19 patients: 3-year follow-up of a randomized, double-blind, placebo-controlled trial

Meng-Qi Yuan, Le Song, Zerui Wang, Zi-Ying Zhang, M. Shi, Junli He, Qiong Mo, Ning Zheng, Wei-Qi Yao, Yu Zhang, T. Dong, Yuan-Yuan Li, Chao Zhang, Jinwen Song, Lei Huang, Zhe Xu, Xin Yuan, Jun-Liang Fu, Cheng Zhen, Jianming Cai, Jinghui Dong, Jianzeng Zhang, Wei-Fen Xie, Yong-Gang Li, Bo Zhang, Lei Shi, Furang Wang

Stem cell research & therapeutics

DOI

2025

Single-cell transcriptomic profiling reveals dysregulation of B-cell subset function in patients with chronic hepatitis B

Jing Li, Siyuan Chen, Cheng Zhen, Pei-Yao Fan, Li-Li Tang, Yang Zhang, Fu-Sheng Wang, Chao Zhang

Hepatology International

DOI

2025

GNLY+CD8+ T cells bridge premature aging and persistent inflammation in people living with HIV

Hui-Fang Wang, Chao Zhang, Liping Zhang, Cheng Zhen, Liang Zhao, Huihuang Huang, Baopeng Yang, Si-Yuan Chen, Wei-Zhe Li, Ming-Ju Zhou, Qiang Guo, Xia Li, Bai-Lu Yin, Fang Sun, Jiyuan Zhang, Zhi-Xin Zhang, Fu-Sheng Wang, Qing-Lei Zeng

Emerging Microbes and Infections

DOI

2025

Dysfunction and Metabolic Reprogramming of Gut Regulatory T Cells in HIV-Infected Immunological Non-Responders

Minrui Yu, Mengmeng Qu, Zerui Wang, Cheng Zhen, Baopeng Yang, Yi Zhang, Huihuang Huang, Chao Zhang, Jinwen Song, Xing Fan, Ruo-Nan Xu, Yan-Mei Jiao, Fu-Sheng Wang

Cells

DOI

2025

Single-cell profiling reveals immunometabolic remodeling with T-cell dysfunction in HIV-1 infected people

Jinfang Zhao, Cheng Zhen, You Wang, Ming-Ju Zhou, Yong Sun, Huihuang Huang, Yan-Mei Jiao, Jin-Wen Song, Xing Fan, Xin Zhang, Tian Jiang, Chao Zhang, Fu-Sheng Wang

Infectious Diseases & Immunity

DOI

2024

Functional cure is associated with younger age in children undergoing antiviral treatment for active chronic hepatitis B

Min Zhang, Jing Li, Zhi-Qiang Xu, Pei-Yao Fan, Yi Dong, Fu-Chuan Wang, Yinjie Gao, Jianguo Yan, L. Cao, D. Ji, D. Feng, Yan-Wei Zhong, Yang Zhang, W. Hong, Chao Zhang, Furang Wang

Hepatology International

DOI

2024

New hope for cure of HIV-infected patients

Yan-Mei Jiao, Chao Zhang, Furang Wang

Infectious Diseases & Immunity

DOI

2024

Manipulating the 4-1BB Pathway to Cure HBV

Chao Zhang, Furang Wang

Infectious Diseases & Immunity

DOI

2024

Landscape of gut mucosal immune cells showed gap of follicular or memory B cells into plasma cells in immunological non‐responders

Zerui Wang, Cheng Zhen, Xiaoyan Guo, Mengmeng Qu, Chao Zhang, Jin-Wen Song, Xing Fan, Huihuang Huang, Ruo-Nan Xu, Jiyuan Zhang, Jinhong Yuan, W. Hong, Jiaying Li, Fu-Sheng Wang, Yan-Mei Jiao, En-Qiang Linghu

Clinical and Translational Medicine

DOI

2024

HLA-mismatched allogeneic adoptive immune therapy in patients with severely immunosuppressed AIDS: a multicenter, open-label, controlled, phase 2a study

Tao Yang, Zhi-Man Xie, Zhe Xu, Bo Tu, Huan Lu, Huihuang Huang, Lei Huang, Chao Zhang, Liying Gao, Lei-Yang Jin, P. Ma, Jun Zou, Liming Liu, Cheng Zhen, Chunbao Zhou, S. Meng, Yuan-Yuan Li, Jin-Wen Song, Shixiong Yang, Hui-Sheng Ai, Yan-Mei Jiao, M. Shi, Ruo-Nan Xu, Furang Wang

Emerging Microbes and Infections

DOI

2024

HBeAg induces neutrophils activation impairing NK cells function in patients with chronic hepatitis B

Zhiqian Feng, Junliang Fu, Li-Li Tang, Chun-Mei Bao, Hong-Hong Liu, Kai Liu, Tao Yang, Jinhong Yuan, Chun-Bao Zhou, Chao Zhang, Ruo-Nan Xu, Fu-Sheng Wang

Hepatology International

DOI

2024

Omicron neutralization character in patients with breast cancer and liver cancer after the nationwide omicron outbreak

Shaohua Zhang, Li-Li Tang, Chun-Mei Bao, Si-Yu Wang, Bo Li, Lei Huang, Hua Song, Junliang Fu, Zhe Xu, Fan-Ping Meng, Ling Cao, Ying-Ying Gao, Yue Yuan, Yang Chen, Jinhong Yuan, Chunbao Zhou, Fan Li, L. P. Qin, Ying Guo, Chao Zhang, Jin-Wen Song, Xing Fan, Ze-Fei Jiang, Fu-Sheng Wang, Ruo-Nan Xu

Cancer Medicine

DOI

2024

Implications of accumulation of clonally expanded and senescent CD4+GNLY+ T cells in immunological non-responders of HIV-1 infection

Xiu-Han Yang, Cheng Zhen, Huihuang Huang, Yan-Mei Jiao, Xing Fan, Chao Zhang, Jin-Wen Song, Song-Yau Wang, Chunbao Zhou, Xin-Xin Yang, Jinhong Yuan, Jiyuan Zhang, Ruo-Nan Xu, Fu-Sheng Wang

Emerging Microbes and Infections

DOI

2024

T-Cell Epitope Mapping of SARS-CoV-2 Reveals Coordinated IFN-γ Production and Clonal Expansion of T Cells Facilitates Recovery from COVID-19

Xing Fan, Jin-Wen Song, Wen-Jing Cao, Ming-Ju Zhou, Tao Yang, Jing Wang, Fan-Ping Meng, M. Shi, Chao Zhang, Fu-Sheng Wang

Viruses

DOI

2023

Characteristics of blood immune cell profile and their correlation with disease progression in patients infected with HIV-1

Xiaoyan Guo, Mengmeng Qu, Xi Wang, Zerui Wang, Jin-Wen Song, Baopeng Yang, Yun-Tian Guo, Yang Zhang, Chao Zhang, Xing Fan, Wen Xu, Ruo-Nan Xu, Jiyuan Zhang, Si-Yuan Chen, Yan-Mei Jiao, Li-Jun Sun, Fu-Sheng Wang

BMC Infectious Diseases

DOI

2023

Dynamics of SARS-CoV-2 Antibody Responses up to 9 Months Post-Vaccination in Individuals with Previous SARS-CoV-2 Infection Receiving Inactivated Vaccines

Jing Wang, Lei Huang, Nan Guo, Ya-Ping Yao, Chao Zhang, Ruo-Nan Xu, Yan-Mei Jiao, Ya-Qun Li, Yaoru Song, Fu Lee Wang, Xing Fan

Viruses

DOI

2023

Elevated glutamate impedes anti-HIV-1 CD8 + T cell responses in HIV-1-infected individuals on antiretroviral therapy

You Wang, Cheng Zhen, Wei Hu, Huihuang Huang, Yan-Jun Li, Ming-Ju Zhou, Jing Li, Yu Fu, P. Zhang, Xiaoyan Li, Tao Yang, Jin-Wen Song, Xing Fan, J. Zou, S. Meng, Yansong Qin, Yan-Mei Jiao, Ruo-Nan Xu, Ji-Yuan Zhang, Chun-Bao Zhou, Jin-Hong Yuan, Lei Huang, M. Shi, Liang Cheng, Fu Lee Wang, Chao Zhang

Communications Biology

DOI

2023

Advances and Challenges of Epidemic Outbreaks in the Post-COVID-19 Era in China

Chao Zhang, Ji-Yuan Zhang, Furang Wang

Infectious Diseases & Immunity

DOI

2023

The burden of cirrhosis and other chronic liver diseases due to hepatitis B in children and adolescents: results from global burden of disease study 2019

Chen-Yang Huang, Ya-Xin Wu, Chao Zhang, D. Ji, Furang Wang

Frontiers in Public Health

DOI

2023

Cured HCV patients with suboptimal hepatitis B vaccine response exhibit high self-reactive immune signatures

Ming-Ju Zhou, Chao Zhang, Yuansong Fu, Haiyan Wang, Yingjie Ji, Xia Huang, Lin Li, Ye Wang, Song Qing, Yan-Chao Shi, Lili Shen, You Wang, Xiaoyan Li, Yuan-Ying Li, Si-Yuan Chen, Cheng Zhen, Ruo-Nan Xu, M. Shi, Fu Lee Wang, Yong-Qian Cheng

Hepatology Communications

DOI

2023

Effect of SARS-CoV-2 Breakthrough Infection on HIV Reservoirs and T-Cell Immune Recovery in 3-Dose Vaccinated People Living with HIV

Mengmeng Qu, Bing Song, Baopeng Yang, Zerui Wang, Minrui Yu, Yi Zhang, Chao Zhang, Jin-Wen Song, Xing Fan, Ruo-Nan Xu, Jiyuan Zhang, Chun-Bao Zhou, F. Du, Fu-Sheng Wang, Huihuang Huang, Yan-Mei Jiao

Viruses

DOI

2023

Severe intestinal barrier damage in HIV-infected immunological non-responders

Xiaoyan Guo, Yun-Tian Guo, Zerui Wang, Yan-Mei Jiao, Yue Hu, Lina Fan, Rui Cheng, Mengmeng Qu, Chao Zhang, Jin-Wen Song, Ruo-Nan Xu, Xing Fan, Wen Xu, Jiyuan Zhang, B. Bai, En-Qiang Linghu, Yao-Kai Chen, P. Ma, Furang Wang

Heliyon

DOI

2023

Why is the functional cure rate of young children with chronic hepatitis B receiving antiviral therapy considerably high?

Furang Wang, Jing Li, Chao Zhang

Hepatology International

DOI

2023

Abnormal blood microbiota profiles are associated with inflammation and immune restoration in HIV/AIDS individuals

Xiaoyan Guo, Zerui Wang, Mengmeng Qu, Yun-Tian Guo, Minrui Yu, W. Hong, Chao Zhang, Xing Fan, Jin-Wen Song, Ruo-Nan Xu, Jiyuan Zhang, Huihuang Huang, E. Linghu, Fu Lee Wang, Li-Jun Sun, Yan-Mei Jiao

mSystems

DOI

2023

Functional Cure of Chronic Hepatitis B with Antiviral Treatment in Children having High-level Viremia and Normal or Mildly Elevated Serum Aminotransferase

Jing Li, Pei-Yao Fan, Zhiqiang Xu, Yi Dong, Fuchuan Wang, W. Hong, Jinfang Zhao, Yin-Jie Gao, Jianguo Yan, L. Cao, Chao Zhang, Shishu Zhu, Fu Lee Wang, Min Zhang

Journal of Clinical and Translational Hepatology

DOI

2023

Clinical Epidemiology, Illness Profiles, and the Implication of COVID-19 Before and After the Nationwide Omicron Outbreak During the Winter of 2022

Yu-Ming Guo, Zhe Xu, Wen-Xin Wang, Cheng Zhen, Jin-Hua Hu, Jinsong Mu, Cheng-Cheng Ji, Xin Yuan, Ruo-Nan Xu, Lei Huang, Lei Shi, Fan-Ping Meng, Jun-Liang Fu, Shuangnan Zhou, Si-Yu Wang, Feng-Yi Li, B. Tu, Dawei Zhang, Huihuang Huang, Yufeng Mao, Wen Xu, Chao Zhang, Xiuying Mu, Jun Zhao, B. Jin, Haibin Su, Yinying Lu, Yong-Qian Cheng, D. Ji, Shao-Li You, Jing-hui Dong, Changchun Liu, Meng-Meng Zhang, Yuan-Yuan Li, Tianjun Jiang, Yong-Gang Li, Furang Wang

Medicine

DOI

2023

Metabolic interventions improve HBV envelope-specific T-cell responses in patients with chronic hepatitis B

Yu Fu, Shuang-Nan Zhou, Wei Hu, Jing Li, Ming-Ju Zhou, Xiaoyan Li, You Wang, P. Zhang, Si-Yuan Chen, Xing Fan, Jin-Wen Song, Yan-Mei Jiao, Ruo-Nan Xu, Ji-Yuan Zhang, Cheng Zhen, Chun-Bao Zhou, Jin-Hong Yuan, M. Shi, Fu Lee Wang, Chao Zhang

Hepatology International

DOI

2023

The Imbalance Between Intestinal Th17 and Treg Cells Is Associated with an Incomplete Immune Reconstitution During Long-Term Antiretroviral Therapy in Patients with HIV

Yun-Tian Guo, Xiao-yan Guo, Li-Na Fan, Ze-Rui Wang, Mengmeng Qu, Chao Zhang, Xing Fan, Jin-Wen Song, Wen-Xu, Baopeng Yang, Ji-Yuan Zhang, Ruo-Nan Xu, Yan-Mei Jiao, P. Ma, Yao-Kai Chen, Fu Lee Wang

Viral immunology

DOI

2023

Human mesenchymal stem cell therapy in severe COVID-19 patients: 2-year follow-up results of a randomized, double-blind, placebo-controlled trial

Tiantian Li, Bo Zhang, Hui Fang, M. Shi, Wei-Qi Yao, Yuan-Yuan Li, Chao Zhang, Jin-Wen Song, Lei Huang, Zhe Xu, Xin Yuan, Jun-Liang Fu, Cheng Zhen, Yu Zhang, Ze-Rui Wang, Zi-Ying Zhang, M. Yuan, T. Dong, Rui-Dan Bai, Lu-Lu Zhao, Jian-Ming Cai, Jing-Hui Dong, Jianzeng Zhang, Wei-Xian Xie, Yong-Gang Li, Lei Shi, Furang Wang

EBioMedicine

DOI

2022

TNFα诱导STAT3信号转导的分子机制研究

曹婷，张朝，胡玲，蒋斌元，胡锦跃

《中国细胞生物学学报》

2022

Global transcriptomic characterization of T cells in individuals with chronic HIV-1 infection

Xiang-Ming Wang, Ji-Yuan Zhang, Xudong Xing, Huihuang Huang, P. Xia, Xiao-Peng Dai, Wei Hu, Chao Zhang, Jin-Wen Song, Xing Fan, Fengbo Wu, Fu-Hua Liu, Y. Ke, Yifan Zhao, Tian Jiang, Lifeng Wang, Yan-Mei Jiao, Ruo-Nan Xu, Lei Jin, M. Shi, Fan Bai, Furang Wang

Cell Discovery

DOI

2022

Prolonged Viral Shedding in Three Young Adult Cases of COVID-19

Wen Dong, Ming-Ju Zhou, Lei Huang, Chao Zhang, Fu-sheng Wang, Zhou-Hua Xie

Infectious Diseases & Immunity

DOI

2022

Reduction of natural killer cells is associated with poor outcomes in patients with hepatitis B virus-related acute-on-chronic liver failure

Huajie Li, Ning Yang, Xiuying Mu, Li‐Chuan Tang, Song-Shan Wang, Chun-Bao Zhou, Jin-Hong Yuan, Haiying Wang, Ying-Ying Yu, Jing Li, Siyu Chen, Zhiqian Feng, Tao Yang, Kai Liu, Wen-Jing Cao, Ming-Ju Zhou, Chao Zhang, Ji-Yuan Zhang, Yan-Mei Jiao, Jin-Wen Song, Xing Fan, M. Shi, Ruo-Nan Xu, Furang Wang

Hepatology International

DOI

2022

Activation-induced pyroptosis contributes to the loss of MAIT cells in chronic HIV-1 infected patients

P. Xia, X. Xing, Cui-Xian Yang, X. Liao, Fu-Hua Liu, Huihuang Huang, Chao Zhang, Jin-Wen Song, Yan-Mei Jiao, M. Shi, Tianjun Jiang, Chun-Bao Zhou, Xi-cheng Wang, Qing He, Qing-Lei Zeng, Fu-Sheng Wang, Ji-Yuan Zhang

Military Medical Research

DOI

2022

Characterization and distribution of HIV-infected cells in semen

Lin Gao, Yan-Mei Jiao, P. Ma, Li-Jun Sun, Hongxin Zhao, Anliang Guo, Xing Fan, Chao Zhang, Jin-Wen Song, Ji-Yuan Zhang, Fengmin Lu, Fu-sheng Wang

Emerging Microbes and Infections

DOI

2022

Low platelets: a new and simple prognostic marker for patients with hepatitis E virus-related acute liver failure

Xiuying Mu, J. Zou, Jing Chen, J. Tong, Lianfei Ma, P. Ning, Huajie Li, Zhi-xian Feng, Tao Yang, Kai Liu, Wen-Jing Cao, Ming-Ju Zhou, Chao Zhang, Ji-Yuan Zhang, Yan-Mei Jiao, Jin-Wen Song, Xing Fan, M. Shi, Jin-Hua Hu, Ruo-Nan Xu, Fu-Sheng Wang

Hepatology International

DOI

2022

Engineered anti-PDL1 with IFNα targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance

Chao-yang Meng, Shiyu Sun, Yong Liang, Hairong Xu, Chao Zhang, M. Zhang, Furang Wang, Yangbo Fu, Hua Peng

Gut

DOI

2022

CCL5-Secreting Virtual Memory CD8+ T Cells Inversely Associate With Viral Reservoir Size in HIV‐1−Infected Individuals on Antiretroviral Therapy

Wei Hu, Yan-Jun Li, Cheng Zhen, You Wang, Huihuang Huang, J. Zou, Yan-Qing Zheng, Gui-Chan Huang, S. Meng, Jiehua Jin, Jing Li, Ming-Ju Zhou, Yu Fu, Peng Zhang, Xiaoyan Li, Tao Yang, Xiu-Wen Wang, Xiugao Yang, Jin-Wen Song, Xing Fan, Yan-Mei Jiao, Ruo-Nan Xu, Ji-Yuan Zhang, Chun-Bao Zhou, Jin-Hong Yuan, Lei Huang, Ya-Qin Qin, Feng-Yao Wu, M. Shi, Furang Wang, Chao Zhang

Frontiers in Immunology

DOI

2022

Immune Dysfunctions of CD56neg NK Cells Are Associated With HIV-1 Disease Progression

Wen-Jing Cao, Xiao-Chang Zhang, Lingfei Wan, Qing-yu Li, Xiuying Mu, Anliang Guo, Ming-Ju Zhou, Lihui Shen, Chao Zhang, Xing Fan, Yan-Mei Jiao, Ruo-Nan Xu, Chun-Bao Zhou, Jin-Hong Yuan, Sheng-qi Wang, Fu-Sheng Wang, Jin-Wen Song

Frontiers in Immunology

DOI

2022

Revisiting the role of human memory CD8+ T cells in immune surveillance

Youfei Wang, Wei Hu, Furang Wang, Chao Zhang

Cellular & Molecular Immunology

DOI

2022

Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients

Chao Zhang, Jie-Sheng Li, Yong-Qian Cheng, Fan-Ping Meng, Jin-Wen Song, Xing Fan, Hong-Tao Fan, Jing Li, Yu Fu, Ming-Ju Zhou, Wei Hu, Si-Yu Wang, Yuan-Jie Fu, Ji-Yuan Zhang, Ruo-Nan Xu, M. Shi, Xue-Da Hu, Ze-Min Zhang, Xian-Wen Ren, Fu-Sheng Wang

Gut

DOI

2022

Distinct inflammation-related proteins associated with T cell immune recovery during chronic HIV-1 infection

Lin-Yu Wan, Huihuang Huang, Cheng Zhen, Si-Yuan Chen, Bing Song, Wen-Jing Cao, Lihui Shen, Ming-Ju Zhou, Xiao-Chang Zhang, Ruo-Nan Xu, Xing Fan, Ji-Yuan Zhang, M. Shi, Chao Zhang, Yan-Mei Jiao, Jin-Wen Song, Fu-Sheng Wang

Emerging Microbes and Infections

DOI

2022

Molecular mechanism of antibody neutralization of coxsackievirus A16

Chao Zhang, Caixuan Liu, Jinping Shi, Yalei Wang, Cong Xu, Xiaohua Ye, Qingwei Liu, Xue Li, Weihua Qiao, Yannan Yin, Yao Cong, Zhong Wei Huang

Nature Communications

DOI

2021

大肠上皮细胞中MDP活化NOD2诱导耐受性CXCL1、CXCL2、CXCL3和CXCL8表达的分子机制

张朝，曹婷，胡玲，胡锦跃

《中国细胞生物学学报》

2021

HLA-mismatched allogeneic adoptive immune therapy in severely immunosuppressed AIDS patients

Ruo-Nan Xu, Ji-Yuan Zhang, B. Tu, Zhe Xu, Huihuang Huang, Lei Huang, Yan-Mei Jiao, Tao Yang, Chao Zhang, E. Qin, Tianjun Jiang, Yunbo Xie, Yuan-Yuan Li, Lei Jin, Chun-Bao Zhou, M. Shi, M. Guo, Huisheng Ai, Lin-Qi Zhang, Fu-Sheng Wang

Signal Transduction and Targeted Therapy

DOI

2021

Mesenchymal stem cell therapy for severe COVID-19

Lei Shi, Lifeng Wang, Ruo-Nan Xu, Chao Zhang, Yunbo Xie, Kai Liu, Tiantian Li, Wei Hu, Cheng Zhen, Fu-Sheng Wang

Signal Transduction and Targeted Therapy

DOI

2021

Implications of the accumulation of CXCR5+ NK cells in lymph nodes of HIV-1 infected patients

Anliang Guo, Yan-Mei Jiao, Qi-Wen Zhao, Huihuang Huang, Jian-Ning Deng, Chao Zhang, Xing Fan, Ruo-Nan Xu, Ji-Yuan Zhang, Cheng Zhen, Zhiyue Xie, Ying-Mei Qin, Jian-Qing Xu, Yu Yang, M. Shi, Lei Huang, Jin-Wen Song, Fu-Sheng Wang

EBioMedicine

DOI

2021

A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19

Sin-Man Lam, Chao Zhang, Ze-Hua Wang, Zhen Ni, Shaohua Zhang, Si-Yuan Yang, Xia-He Huang, Le-Song Mo, Jie Li, Bernett Lee, Mei Mei, Lei Huang, M. Shi, Zhe Xu, Fan-Ping Meng, Wen-Jing Cao, Ming-Ju Zhou, Lei Shi, Gek Huey Chua, Bo-Wen Li, Jiabao Cao, Jun Wang, Shi-Lai Bao, Ying-Chun Wang, Jin-Wen Song, Fu-Jie Zhang, Fu-Sheng Wang, Guang-Hou Shui

Nature Metabolism

DOI

2021

Human mesenchymal stem cells treatment for severe COVID-19: 1-year follow-up results of a randomized, double-blind, placebo-controlled trial

Lei Shi, Xin Yuan, Wei-Qi Yao, Si-Yu Wang, Chao Zhang, Bo Zhang, Jin-Wen Song, Lei Huang, Zhe Xu, Jun-Liang Fu, Yuan-Yuan Li, Ruo-Nan Xu, Tian-Tian Li, Jing-Hui Dong, Jianming Cai, Gen Li, Yunbo Xie, M. Shi, Yong-Gang Li, Yu Zhang, Weidun Xie, Fulian Wang

EBioMedicine

DOI

2021

The Progress and Challenges of Convalescent Plasma Therapy for Coronavirus Disease 2019

M. Shi, Chao Zhang, Fu-Sheng Wang

Infectious Diseases & Immunity

DOI

2021

Increased Platelet-CD4+ T Cell Aggregates Are Correlated With HIV-1 Permissiveness and CD4+ T Cell Loss

Xiao-Peng Dai, Fengbo Wu, Cheng Cui, Xue-Jiao Liao, Yan-Mei Jiao, Chao Zhang, Jin-Wen Song, Xing Fan, Ji-Yuan Zhang, Qing He, Fu-Sheng Wang

Frontiers in Immunology

DOI

2021

Reversal of the CD8+ T-Cell Exhaustion Induced by Chronic HIV-1 Infection Through Combined Blockade of the Adenosine and PD-1 Pathways

Jing Li, Huihuang Huang, B. Tu, Ming-Ju Zhou, Wei Hu, Yu Fu, Xiao-Yu Li, Tao Yang, Jin-Wen Song, Xing Fan, Yan-Mei Jiao, Ruo-Nan Xu, Ji-Yuan Zhang, Chun-Bao Zhou, Jin-Hong Yuan, Cheng Zhen, M. Shi, Fu-Sheng Wang, Chao Zhang

Frontiers in Immunology

DOI

2021

Author response for "Compromised long‐lived memory CD8+ T cells are associated with reduced IL‐7 responsiveness in HIV‐infected immunological non‐responders"

Ming-Ju Zhou, Huihuang Huang, Jin-Wen Song, Bo-Xuan Tu, Xing Fan, Jing Li, Jiehua Jin, Wen-Jing Cao, Wei Hu, Tao Yang, Chun-Bao Zhou, Jin-song Yuan, Jin Fan, Ji-Yuan Zhang, Yan-Mei Jiao, Ruo-Nan Xu, Cheng Zhen, M. Shi, Chao Zhang, Furang Wang

DOI

2021

Compromised long‐lived memory CD8+ T cells are associated with reduced IL‐7 responsiveness in HIV‐infected immunological nonresponders

Ming-Ju Zhou, Huihuang Huang, Jin-Wen Song, B. Tu, Xing Fan, Jing Li, Jiehua Jin, Wen-Jing Cao, Wei Hu, Tao Yang, Chun-Bao Zhou, Jin-Hong Yuan, Jin Fan, Ji-Yuan Zhang, Yan-Mei Jiao, Ruo-Nan Xu, Cheng Zhen, M. Shi, Chao Zhang, Fu-Sheng Wang

European Journal of Immunology

DOI

2021

HIV-1-Specific CD11c+ CD8+ T Cells Display Low PD-1 Expression and Strong Anti-HIV-1 Activity

Anliang Guo, Jinfang Zhao, Lin Gao, Huihuang Huang, Ji-Yuan Zhang, Chao Zhang, Jin-Wen Song, Ruo-Nan Xu, Xing Fan, M. Shi, Yan-Mei Jiao, Fu-Sheng Wang

Frontiers in Immunology

DOI

2021

Increased Neutrophil Aging Contributes to T Cell Immune Suppression by PD-L1 and Arginase-1 in HIV-1 Treatment Naïve Patients

Kai Liu, Huihuang Huang, Tao Yang, Yan-Mei Jiao, Chao Zhang, Jin-Wen Song, Ji-Yuan Zhang, Chun-Bao Zhou, Jin-Hong Yuan, Wen-Jing Cao, Xiuying Mu, Ming-Ju Zhou, Huajie Li, M. Shi, Ruo-Nan Xu, Fu-Sheng Wang

Frontiers in Immunology

DOI

2021

Changes of Damage Associated Molecular Patterns in COVID-19 Patients

Xing Fan, Jin-Wen Song, Si-Yu Wang, Wen-Jing Cao, Xiu-Feng Wang, Ming-Ju Zhou, Tao Yang, Chun-Bao Zhou, Jun Hou, Ji-Yuan Zhang, Fan-Ping Meng, M. Shi, Fu-Sheng Wang, Chao Zhang

Infectious Diseases & Immunity

DOI

2021

Systematic Discovery and Pathway Analyses of Metabolic Disturbance in COVID-19

Bo-Wen Li, Xing Fan, Wen-Jing Cao, He Tian, Si-Yu Wang, Ji-Yuan Zhang, Sin-Man Lam, Jin-Wen Song, Chao Zhang, Shao-hua Zhang, Zhe Xu, Ruo-Nan Xu, Jun-Liang Fu, Lei Huang, Tian Jiang, M. Shi, Fu-Sheng Wang, Guang-Hou Shui

Infectious Diseases & Immunity

DOI

2021

NLRP3 inflammasome induces CD4+ T cell loss in chronically HIV-1-infected patients.

Chao Zhang, Jin-Wen Song, Huihuang Huang, Xing Fan, Lei Huang, Jian-Ning Deng, B. Tu, Kun Wang, Jing Li, Ming-Ju Zhou, Cui-Xian Yang, Qi-Wen Zhao, Tao Yang, Lifeng Wang, Ji-Yuan Zhang, Ruo-Nan Xu, Yan-Mei Jiao, M. Shi, F. Shao, R. Sékaly, Fu-Sheng Wang

Journal of Clinical Investigation

DOI

2021

Dynamics of HIV reservoir decay and naïve CD4 T-cell recovery between immune non-responders and complete responders on long-term antiretroviral treatment.

Luxue Zhang, Jin-Wen Song, Chao Zhang, Xing Fan, Huihuang Huang, Ruo-Nan Xu, Jia-Ye Liu, Ji-Yuan Zhang, Lifeng Wang, Chun-Bao Zhou, Lei Jin, M. Shi, Fu-Sheng Wang, Yan-Mei Jiao

Clinical Immunology

DOI

2020

血管非炎性分子1的生理及病理生理作用

张茵，张朝

《生命科学》

DOI

2020

Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial

Lei Shi, Hai Huang, Xue Lu, Xiao-Yan Yan, Xiao-Jing Jiang, Ruo-Nan Xu, Si-Yu Wang, Chao Zhang, Xin Yuan, Zhe Xu, Lei Huang, Jun-Liang Fu, Yuan-Yuan Li, Yu Zhang, Wei-Qi Yao, Tian-Yi Liu, Jin-Wen Song, Liang-Liang Sun, Fan Yang, Xin Zhang, Bo Zhang, M. Shi, Fan-Ping Meng, Yan-Ning Song, Yong-Pei Yu, Ji Wen, Qi Li, Q. Mao, M. Maeurer, Alimuddin Zumla, C. Yao, Wei Xie, Fu-Sheng Wang

Signal Transduction and Targeted Therapy

DOI

2020

Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial

Fan-Ping Meng, Ruo-Nan Xu, Si-Yu Wang, Zhe Xu, Chao Zhang, Yuan-Yuan Li, Tao Yang, Lei Shi, Jun-Liang Fu, Tianjun Jiang, Lei Huang, Peng Zhao, Xin Yuan, Xing Fan, Ji-Yuan Zhang, Jin-Wen Song, Dawei Zhang, Yan-Mei Jiao, Liming Liu, Chun-Bao Zhou, M. Maeurer, Alimuddin Zumla, M. Shi, Fu-Sheng Wang

Signal Transduction and Targeted Therapy

DOI

2020

Single-cell landscape of immunological responses in patients with COVID-19

Ji-Yuan Zhang, Xiang-Ming Wang, Xudong Xing, Zhe Xu, Chao Zhang, Jin-Wen Song, Xing Fan, P. Xia, Jun-Liang Fu, Si-Yu Wang, Ruo-Nan Xu, Xiao-Peng Dai, Lei Shi, Lei Huang, Tianjun Jiang, M. Shi, Yu-Xia Zhang, Alimuddin Zumla, M. Maeurer, F. Bai, Fu-Sheng Wang

Nature Immunology

DOI

2020

Is aberrant CD8+ T cell activation by hypertension associated with cardiac injury in severe cases of COVID-19?

Chao Zhang, Fu-Sheng Wang, J. Silvestre, F. Arenzana-Seisdedos, Hong Tang

Cellular & Molecular Immunology

DOI

2020

Mortality in COVID-19 disease patients: Correlating the association of major histocompatibility complex (MHC) with severe acute respiratory syndrome 2 (SARS-CoV-2) variants

E. de Sousa, D. Ligeiro, Joana R. Lérias, Chao Zhang, C. Agrati, Mohamed Osman, S. El-Kafrawy, E. Azhar, G. Ippolito, Fu-Sheng Wang, A. Zumla, M. Maeurer

International Journal of Infectious Diseases

DOI

2020

What to do next to control the 2019-nCoV epidemic?

Fu-Sheng Wang, Chao Zhang

The Lancet

DOI

2020

Higher Death Rates in the Italian COVID-19 Outbreak: A Comparative Modelling Analysis of 8,342 Italy and 44,672 China Cases

S. Lanini, F. Vairo, V. Puro, P. Scognamiglio, F. Locatelli, Chao Zhang, Fu-Sheng Wang, Alimuddin Zumla, G. Ippolito

Social Science Research Network

DOI

2020

Immunometabolism: new insights and lessons from antigen-directed cellular immune responses

Renata Ramalho, Martin Rao, Chao Zhang, C. Agrati, G. Ippolito, Fu-Sheng Wang, Alimuddin Zumla, M. Maeurer

Seminars in Immunopathology

DOI

2020

Liver injury in COVID-19: management and challenges

Chao Zhang, Lei Shi, Fu-Sheng Wang

The Lancet Gastroenterology and Hepatology

DOI

2020

Immunological and inflammatory profiles in mild and severe cases of COVID-19

Jin-Wen Song, Chao Zhang, Xing Fan, Fan-Ping Meng, Zhe Xu, P. Xia, Wen-Jing Cao, Tao Yang, Xiao-Peng Dai, Si-Yu Wang, Ruo-Nan Xu, Tianjun Jiang, Wen-Gang Li, Da-Wei Zhang, Peng Zhao, M. Shi, C. Agrati, G. Ippolito, M. Maeurer, Alimuddin Zumla, Fu-Sheng Wang, Ji-Yuan Zhang

Nature Communications

DOI

2020

Virtual memory CD8+ T cells restrain the viral reservoir in HIV-1-infected patients with antiretroviral therapy through derepressing KIR-mediated inhibition

Jiehua Jin, Huihuang Huang, Ming-Ju Zhou, Jing Li, Wei Hu, Lei Huang, Zhe Xu, B. Tu, Guang Yang, M. Shi, Yan-Mei Jiao, Xing Fan, Jin-Wen Song, Ji-Yuan Zhang, Chao Zhang, Fu-Sheng Wang

Cellular & Molecular Immunology

DOI

2020

Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

C. Agrati, A. Sacchi, V. Bordoni, E. Cimini, Stefania Notari, G. Grassi, R. Casetti, E. Tartaglia, E. Lalle, A. D'Abramo, C. Castilletti, L. Marchioni, Yufang Shi, A. Mariano, Jin-Wen Song, Ji-Yuan Zhang, Fu-Sheng Wang, Chao Zhang, G. Fimia, M. Capobianchi, M. Piacentini, A. Antinori, E. Nicastri, M. Maeurer, Alimuddin Zumla, G. Ippolito

Cell Death and Differentiation

DOI

2020

Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis

Jin-Wen Song, S. Lam, Xing Fan, Wen-Jing Cao, Si-Yu Wang, He Tian, Gek Huey Chua, Chao Zhang, Fan-Ping Meng, Zhe Xu, Jun-Liang Fu, Lei Huang, P. Xia, Tao Yang, Shaohua Zhang, Bo-Wen Li, Tianjun Jiang, Raoxu Wang, Ze-Hua Wang, M. Shi, Ji-Yuan Zhang, Fu-Sheng Wang, Guang-Hou Shui

Cell Metabolism

DOI

2020

HIV Reservoir Decay and CD4 Recovery Associated With High CD8 Counts in Immune Restored Patients on Long-Term ART

Luxue Zhang, Yan-Mei Jiao, Chao Zhang, Jin-Wen Song, Xing Fan, Ruo-Nan Xu, Huihuang Huang, Ji-Yuan Zhang, Lifeng Wang, Chun-Bao Zhou, Lei Jin, M. Shi, Fu-Sheng Wang

Frontiers in Immunology

DOI

2020

Transforming growth factor‐β promotes the function of HIV‐specific CXCR5+CD8 T cells

Hong-Ge Yang, Yan-Mei Jiao, Huihuang Huang, Chao Zhang, Ji-Yuan Zhang, Ruo-Nan Xu, Jin-Wen Song, Xing Fan, Lei Jin, M. Shi, Fu-Sheng Wang

Microbiology and immunology

DOI

2020

Hepatitis C: milestones from discovery to clinical cure

Wei Hu, Chao Zhang, Ji-Jing Shi, Ji-Yuan Zhang, Fu-Sheng Wang

Military Medical Research

DOI

2020

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

Zhe Xu, Lei Shi, Yijin Wang, Ji-Yuan Zhang, Lei Huang, Chao Zhang, Shu-Hong Liu, Peng Zhao, Hong-Xia Liu, Li Zhu, Y. Tai, Chang-Qing Bai, T. Gao, Jin-Wen Song, P. Xia, Jing-Hui Dong, Jing-Min Zhao, Fu-Sheng Wang

The Lancet Respiratory Medicine

DOI

2020

CD4+CD19+ conjugates favor HIV-1 infection and latency during chronic HIV-1 infection.

He-Qiang Zhang, P. Xia, Huihuang Huang, Chao Zhang, Jin-Wen Song, Lei Jin, Yan-Mei Jiao, M. Shi, Fu-Sheng Wang, Ji-Yuan Zhang

AIDS (London)

DOI

2020

Skewed CD39/CD73/adenosine pathway contributes to B-cell hyperactivation and disease progression in patients with chronic hepatitis B

Shuang-Nan Zhou, Ning Zhang, Hong-Hong Liu, P. Xia, Chao Zhang, Jin-Wen Song, Xing Fan, M. Shi, Lei Jin, Ji-Yuan Zhang, Fu-Sheng Wang

Gastroenterology Report

DOI

2019

Skewed CD39/CD73/adenosine pathway in B cells is associated with innate immune hyperactivation in chronic HIV-1 infection

Wen-xian Chang, Huihuang Huang, Lei Huang, Ji-Jing Shi, Yan-Mei Jiao, Chao Zhang, Lei Jin, Tao Yang, M. Shi, B. Tu, Zhe Xu, Tianjun Jiang, Fu-Sheng Wang, Ji-Yuan Zhang

Translational Medicine Communications

DOI

2019

Expression of CD39 Is Correlated With HIV DNA Levels in Naïve Tregs in Chronically Infected ART Naïve Patients

Jin-Wen Song, Huihuang Huang, Chao Zhang, Hong-Ge Yang, Ji-Yuan Zhang, Ruo-Nan Xu, Lei Jin, M. Shi, Fu-Sheng Wang, Yan-Mei Jiao

Frontiers in Immunology

DOI

2018

High levels of circulating GM-CSF+CD4+ T cells are predictive of poor outcomes in sepsis patients: a prospective cohort study

Huihuang Huang, Si-Yu Wang, Tianjun Jiang, Rong Fan, Zheng Zhang, J. Mu, Ke Li, Yonggang Wang, Lei Jin, F. Lin, J. Xia, Lijian Sun, Biao Xu, Cheng-Cheng Ji, Jing Chen, Juan Chang, B. Tu, Bing Song, Chao Zhang, Fu-Sheng Wang, Ruo-Nan Xu

Cellular & Molecular Immunology

DOI

2010

人Snapin基因片段的原核表达及多克隆抗体的制备

张沙沙，陈中，赵钟钟，孙晓莉，袁秀杰，张朝

《免疫学杂志》

2008

安妥沙星延长离体豚鼠心肌动作电位

尚曙玉，韩圣娜，景莹，成树模，乔鹏，张朝

《基础医学与临床》

2007

左氧氟沙星延长离体豚鼠乳头肌的动作电位时程

尚曙玉，韩圣娜，景莹，成树模，韦迎娜，乔鹏，张朝

《基础医学与临床》

2001

睡眠剥夺对大鼠免疫功能的影响

袁义强，乔鹏，章茜，王书春，张朝，王雨若

《基础医学与临床》

会议论文

2009

小鼠心脏发育过程中钙离子通道的表达

张沙沙，钱辉，赵钟钟，袁秀杰，石洁，刘金旭，郭佳，朱中华，胡振盛，张香梅，张朝

《第十一届中国细胞生物学学术大会暨2009西安细胞生物学国际会议》

2003

小鼠心房、心室细胞表达小电导钙激活钾通道

许彦芳，Dipika Tuteja，张朝，Jennifer Rodriguez，Nipavan Chiamvimonvat

《2003全国中青年药理学英文学术报告会》

2002

心肌细胞内Ca 2+ 对细胞膜K + 电流的调控作用

许彦芳，张朝，Jennifer Rodriguez，Nipavan Chiamvimonvat

《中国药理学会第八次全国代表大会论文摘要集（第二部分）》

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