邱彦｜厦门大学｜学者主页

2023

Effect of palmitoylethanolamide on degeneration of a human-derived retinal pigment epithelial cell induced by all-trans retinal

Yun Han, Danxue He, Chaofeng Yu, Lei Tao, Chun-Yan Liao, Binxiang Cai, Zuguo Liu, Yan Qiu, Yalin Wu

International Journal of Ophthalmology

2022

Association between abnormal glycolipid level and cognitive dysfunction in drug-naive patients with bipolar disorder

Yan Qiu, Sujuan Li, Ziwei Teng, Yuxi Tan, Xuelei Xu, Min Yang, Ziru Zhao, Jieyu Liu, Hui Tang, Hui Xiang, Jindong Chen, Bolun Wang, Haishan Wu

Journal Of Affective Disorders，Vol. 297

DOI

2022

N-Acylethanolamine acid amidase (NAAA) exacerbates psoriasis inflammation by enhancing dendritic cell (DCs) maturation

Yuhang Li, Yitian Li, Sennan Xu, Yue Chen, Pan Zhou, Ting Hu, Hua Li, Ying Liu, Yaping Xu, Jie Ren, Yan Qiu, Can‐Zhong Lu

Pharmacological Research

DOI

2022

Genetic Blockade of NAAA Cell-specifically Regulates Fatty Acid Ethanolamides (FAEs) Metabolism and Inflammatory Responses

Xiaohua Xie, Yitian Li, Yitian Li, Sennan Xu, Pan Zhou, Longhe Yang, Yaping Xu, Yan Qiu, Yungang Yang, Yuhang Li, Yuhang Li

Frontiers in Pharmacology

DOI

2021

NAAA inhibitor F96 attenuates BBB disruption and secondary injury after traumatic brain injury (TBI)

Yitian Li, Yitian Li, Pan Zhou, Ting Hu, Jie Ren, Yaping Xu, Yan Qiu, Can‐Zhong Lu, Yuhang Li, Yuhang Li

European Journal of Pharmacology

DOI

2021

Inhibition of ceramide de novo synthesis ameliorates meibomian gland dysfunction induced by SCD1 deficiency

Chunyan Ji, Yuli Guo, Ying Liu, Sennan Xu, Sichen Zhao, Xin Luo, Funan Qiu, Rui Huang, Qing-yan Xu, Ruihe Zheng, Miao Xia, Yun Zhao, Jie Ren, Yan Qiu

The Ocular Surface

DOI

2021

NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis

Ruihe Zheng, Yibo Zhang, Funan Qiu, Zhaohui Liu, Yun Han, Rui Huang, Yun Zhao, Peijie Yao, Yan Qiu, Jie Ren

Cancer Biology & Therapy

DOI

2020

Palmitoylethanolamide (PEA) reduces postoperative adhesions after experimental strabismus surgery in rabbits by suppressing canonical and non-canonical TGFβ signaling through PPARα

Yitian Li, Sichen Zhao, Sennan Xu, Yuhang Li, Chaowei Wang, Jie Ren, Fei Li, Xiaokun Hu, Kuantian Lin, Yan Qiu, Yanghui Xiu

Biochemical Pharmacology

DOI

2020

Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation

Longhe Yang, Chunyan Ji, Yitian Li, Fan Hu, Fang Zhang, Haiping Zhang, Long Li, Jie Ren, Zhaokai Wang, Yan Qiu

Frontiers in Pharmacology

DOI

2020

N-Palmitoylethanolamine Maintains Local Lipid Homeostasis to Relieve Sleep Deprivation–Induced Dry Eye Syndrome

Qi Chen, Chunyan Ji, Ruihe Zheng, Longhe Yang, Jie Ren, Yitian Li, Yun Han, Pan Zhou, Zuguo Liu, Yan Qiu

Frontiers in Pharmacology

DOI

2020

PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis

Sihao Ye, Qian Chen, Nan Jiang, Liang Xu, Jingming Li, Rongrong Zong, Caihong Huang, Yan Qiu, Jian‐xing Ma, Zuguo Liu

Investigative Ophthalmology & Visual Science

DOI

2019

A New Use for an Old Drug: Carmofur Attenuates Lipopolysaccharide (LPS)-Induced Acute Lung Injury via Inhibition of FAAH and NAAA Activities

Kangni Wu, Yanghui Xiu, Pan Zhou, Yan Qiu, Yuhang Li

Frontiers in Pharmacology

DOI

2019

N-Acylethanolamine acid amidase (NAAA) inhibitor F215 as a novel therapeutic agent for osteoarthritis

Pan Zhou, Lei Xiang, Yulong Yang, Yuezhou Wu, Ting Hu, Xiaolong Liu, Feitai Lin, Yanghui Xiu, Kangni Wu, Can‐Zhong Lu, Jie Ren, Yan Qiu, Yuhang Li

Pharmacological Research

DOI

2018

Synthesis, biological evaluation, and structure activity relationship (SAR) study of pyrrolidine amide derivatives as N -acylethanolamine acid amidase (NAAA) inhibitors

Pan Zhou, Lei Xiang, Dongsheng Zhao, Jie Ren, Yan Qiu, Yuhang Li

MedChemComm

DOI

2018

Inflammation-restricted anti-inflammatory activities of a N -acylethanolamine acid amidase (NAAA) inhibitor F215

Yuhang Li, Pan Zhou, Hui-Xia Chen, Qi Chen, Xiaofei Kuang, Can‐Zhong Lu, Jie Ren, Yan Qiu

Pharmacological Research

DOI

2018

Sleep Deprivation Induces Dry Eye Through Inhibition of PPARα Expression in Corneal Epithelium

Liying Tang, Xue Wang, Jieli Wu, San Ming Li, Zhaoqiang Zhang, San‐Gang Wu, Ting Su, Zhirong Lin, Xueting Chen, Xu‐Lin Liao, Ting Bai, Yan Qiu, Peter Sol Reinach, Wei Shan Li, Yongxiong Chen, Zuguo Liu

Investigative Ophthalmology & Visual Science

DOI

2017

Identification of highly potent N -acylethanolamine acid amidase (NAAA) inhibitors: Optimization of the terminal phenyl moiety of oxazolidone derivatives

Yuhang Li, Qi Chen, Longhe Yang, Yanting Li, Yang Zhang, Yan Qiu, Jie Ren, Can‐Zhong Lu

European Journal of Medicinal Chemistry

DOI

2017

Design, synthesis, and biological evaluation of oxazolidone derivatives as highly potent N-acylethanolamine acid amidase (NAAA) inhibitors

Jie Ren, Yuhang Li, Yuhang Li, Hongwei Ke, Yanting Li, Yanting Li, Longhe Yang, Helin Yu, Rui Huang, Can‐Zhong Lu, Yan Qiu

RSC Advances

DOI

2017

Design and synthesis of uracil urea derivatives as potent and selective fatty acid amide hydrolase inhibitors

Yan Qiu, Jie Ren, Hongwei Ke, Yang Zhang, Qi Gao, Longhe Yang, Can‐Zhong Lu, Yuhang Li

RSC Advances

DOI

2016

Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase

Yan Qiu, Yang Zhang, Yuhang Li, Jie Ren

Molecules

DOI

2016

Stearoyl-CoA desaturase-1 mediated cell apoptosis in colorectal cancer by promoting ceramide synthesis

Ling Chen, Jie Ren, Longhe Yang, Yanting Li, Jin Xiang Fu, Yuhang Li, Yifeng Tian, Funan Qiu, Zuguo Liu, Yan Qiu

Scientific Reports

DOI

2015

Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells

Ling Chen, Long Li, Long Li, Junde Chen, Lei Li, Lei Li, Zihan Zheng, Jie Ren, Yan Qiu

Oncotarget

DOI

2015

Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

Longhe Yang, Long Li, Ling Chen, Yanting Li, Huixia Chen, Yuhang Li, Guangnian Ji, Donghai Lin, Zuguo Liu, Yan Qiu

Scientific Reports

DOI

2015

Endocannabinoid and ceramide levels are altered in patients with colorectal cancer

LING CHEN, HUIXIA CHEN, Yanting Li, Lei Li, Yan Qiu, Jie Ren

Oncology Reports

DOI

2014

Effect of oleoylethanolamide on diet-induced nonalcoholic fatty liver in rats

Long Li, Lei Li, Ling Chen, Xiaoyu Lin, Yaping Xu, Jie Ren, Jin Fu, Yan Qiu

Journal of Pharmacological Sciences

DOI

2014

Atheroprotective Effect of Oleoylethanolamide (OEA) Targeting Oxidized LDL

Angran Fan, Xiaofeng Wu, Huijuan Wu, Long Li, Rui Huang, Yueyong Zhu, Yan Qiu, Jin Fu, Jie Ren, Chenggang Zhu

PLoS ONE

DOI

2012

Design and Synthesis of Potent N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitor as Anti-Inflammatory Compounds

Yuhang Li, Longhe Yang, Ling Chen, Chenggang Zhu, Rui Huang, Xiao Zheng, Yan Qiu, Jin Xiang Fu

PLoS ONE

DOI

2011

Alteration of endocannabinoid system in human gliomas

Xi-Yue Wu, Lijun Han, Xiaolin Zhang, Long Li, Changzhen Jiang, Yan Qiu, Rui Huang, Baoying Xie, Zhixiong Lin, Jie Ren, Jin Xiang Fu

Journal of Neurochemistry

DOI

邱彦

精选作品

期刊论文

Effect of palmitoylethanolamide on degeneration of a human-derived retinal pigment epithelial cell induced by all-trans retinal

Association between abnormal glycolipid level and cognitive dysfunction in drug-naive patients with bipolar disorder

N-Acylethanolamine acid amidase (NAAA) exacerbates psoriasis inflammation by enhancing dendritic cell (DCs) maturation

Genetic Blockade of NAAA Cell-specifically Regulates Fatty Acid Ethanolamides (FAEs) Metabolism and Inflammatory Responses

NAAA inhibitor F96 attenuates BBB disruption and secondary injury after traumatic brain injury (TBI)

Inhibition of ceramide de novo synthesis ameliorates meibomian gland dysfunction induced by SCD1 deficiency

NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis

Palmitoylethanolamide (PEA) reduces postoperative adhesions after experimental strabismus surgery in rabbits by suppressing canonical and non-canonical TGFβ signaling through PPARα

Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation

N-Palmitoylethanolamine Maintains Local Lipid Homeostasis to Relieve Sleep Deprivation–Induced Dry Eye Syndrome

PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis

A New Use for an Old Drug: Carmofur Attenuates Lipopolysaccharide (LPS)-Induced Acute Lung Injury via Inhibition of FAAH and NAAA Activities

N-Acylethanolamine acid amidase (NAAA) inhibitor F215 as a novel therapeutic agent for osteoarthritis

Synthesis, biological evaluation, and structure activity relationship (SAR) study of pyrrolidine amide derivatives as N -acylethanolamine acid amidase (NAAA) inhibitors

Inflammation-restricted anti-inflammatory activities of a N -acylethanolamine acid amidase (NAAA) inhibitor F215

Sleep Deprivation Induces Dry Eye Through Inhibition of PPARα Expression in Corneal Epithelium

Identification of highly potent N -acylethanolamine acid amidase (NAAA) inhibitors: Optimization of the terminal phenyl moiety of oxazolidone derivatives

Design, synthesis, and biological evaluation of oxazolidone derivatives as highly potent N-acylethanolamine acid amidase (NAAA) inhibitors

Design and synthesis of uracil urea derivatives as potent and selective fatty acid amide hydrolase inhibitors

Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase

Stearoyl-CoA desaturase-1 mediated cell apoptosis in colorectal cancer by promoting ceramide synthesis

Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells

Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

Endocannabinoid and ceramide levels are altered in patients with colorectal cancer

Effect of oleoylethanolamide on diet-induced nonalcoholic fatty liver in rats

Atheroprotective Effect of Oleoylethanolamide (OEA) Targeting Oxidized LDL

Design and Synthesis of Potent N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitor as Anti-Inflammatory Compounds

Alteration of endocannabinoid system in human gliomas

研究方向