李亚馨｜河南工业大学｜学者主页

2026

Structure-Based Design and Free Energy Perturbation-Guided Synthesis of Novel VEGFR2 and HDAC Dual Inhibitors with Potent Antitumor Efficacy.

Yaxin Li, Sisi Liu, Shao-Han Hu, Ranran Zhang, Xiaoli Wang, Jiamin Xu, Keke Yao, Chenxuan Lu, Guo-Feng Li, Zhigang Wu, Chunyan Guo, Leifu Yang, Liming Hu

Journal of Medicinal Chemistry

DOI

2026

Design and Synthesis of Benzofuran-Pyrazole Hybrids as Dual TGF-βR1/VEGFR-2 Inhibitors for Anticancer Applications

Liming Hu, Yajing Song, Yanan Xu, Keke Yao, Xiaoling Wang, Jiamin Xu, Yaxin Li, Shan Hu

Journal of Molecular Structure

DOI

2026

Structure-based design, synthesis, and biological evaluation of benzofuran derivatives as dual TGF-βR1 and VEGFR2 inhibitors for potent antitumor therapy.

Liming Hu, Yanan Xu, Keke Yao, Xiaoli Wang, Jiamin Xu, Yaxin Li, Shan Hu

Bioorganic chemistry (Print)

DOI

2025

专业学位研究生培养模式改革研究与实践——以材料与化工专业硕士培养为例

谭梦茜，李亚馨，何春雨，马路山，陈静

《大学化学》

2025

食品科学与工程类专业无机化学课程教学改革探索

李亚馨，谭梦茜，闫萌，郭涛，胡乐乾

《化学工程与装备》

DOI

2025

Triclinic Liquid Crystal of Counter-Rotating Squashed Double Helices in a Side-Chain Polymer

Yi‐nan Xue, Yaxin Li, Yumin Tang, Shu-Gui Yang, Ruo‐Yin Jia, Liliana Cseh, Feng Liu, Xiangbing Zeng, Goran Ungar

Journal of the American Chemical Society

DOI

2025

On the Mechanism of Soft Self‐Assembly from Melt: The Ubiquitous Heat Capacity Hump and Spontaneous Melt Chirality

Yi‐nan Xue, Xiangbing Zeng, Bowen Wu, Yaxin Li, Liliana Cseh, Shu-Gui Yang, Jie Liu, Gillian Anne Gehring, Feng Liu, Goran Ungar

Angewandte Chemie

DOI

2024

Discovery of a urea-based hit compound as a novel inhibitor of transforming growth factor-β type 1 receptor: in silico and in vitro studies.

Yaxin Li, Sisi Liu, Zhuo-Ya Wang, Xiaoli Wang, Jiamin Xu, Keke Yao, Ranran Zhang, Chenxuan Lu, Zhigang Wu, Liming Hu

Physical Chemistry, Chemical Physics - PCCP

DOI

2024

Special Issue “Drug Discovery and Application of New Technologies”

Sha Hu, Yaxin Li, Liming Hu

International Journal of Molecular Sciences

DOI

2024

Thermotropic “Plumber's Nightmare”—A Tight Liquid Organic Double Framework

Yaxin Li, Ruo‐Yin Jia, Goran Ungar, Tao Ma, Kai Zhao, Xiang Zeng, Xiaohong Cheng

Angewandte Chemie

DOI

2024

Highly Ordered Gyroid Nanostructured Polymers: Facile Fabrication by Polymerizable Pluronic Surfactants

Yinuo Wang, Yaxin Li, Qing 'an Li, Ruo‐Yin Jia, Qingchen Tang, Hairui Huang, Yizhou Zhang, Xunda Feng

ACS Macro Letters

DOI

2024

Supertwisted Chiral Gyroid Mesophase in Chiral Rod‐Like Compounds

Yan Wang, Shu‐Gui Yang, Yaxin Li, Yu Cao, Feng Liu, Xiangbing Zeng, Liliana Cseh, Goran Ungar

Angewandte Chemie

DOI

2023

合成化学课程教学设计探索——以“碳负离子和碳正离子促进的碳链构建”为例

郭涛，胡乐乾，李亚馨，谢文磊

《广州化工》

2023

Integrated molecular modeling and dynamics approaches revealed the mechanism of selective inhibition of HDAC6/8

Yaxin Li, Sisi Liu, Ximing Xu, Jiamin Xu, Leifu Yang, Liming Hu

Journal of Biomolecular Structure and Dynamics

DOI

2023

Enantiomers Self-Sort into Separate Counter-Twisted Ribbons of the Fddd Liquid Crystal─Antiferrochirality and Parachirality

Yan Wang, Yaxin Li, Liliana Cseh, Yong-Xuan Chen, Shu-Gui Yang, Xiangbing Zeng, Feng Liu, Wenbing Hu, Goran Ungar

Journal of the American Chemical Society

DOI

2023

Cover Feature: The Effect of Mesogenic Coronas on the Type and Anisotropy of Gold Nanoparticle Superlattices: When Can the Tail Wag the Dog? (Chem. Eur. J. 11/2023)

Yangyang Zhao, Yaxin Li, Yu Cao, Georg H. Mehl, Feng Liu, Goran Ungar

Chemistry - A European Journal

DOI

2022

Computational Investigations of Coumarin Derivatives as Cyclin-Dependent Kinase 9 Inhibitors Using 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation.

Sisi Liu, Yaxin Li, Xi-Lin Wei, Ran Zhang, Yifan Zhang, Chun-Yan Guo

Current Computer - Aided Drug Design

DOI

2022

The Effect of Mesogenic Coronas on the Type and Anisotropy of Gold Nanoparticle Superlattices: When Can the Tail Wag the Dog?

Yangyang Zhao, Yaxin Li, Yu Cao, Georg H. Mehl, Feng Liu, Goran Ungar

Chemistry - A European Journal

DOI

2022

A case of antiferrochirality in a liquid crystal phase of counter-rotating staircases

Yaxin Li, Hongfei Gao, Ruibin Zhang, Kutlwano Gabana, Qing Chang, Gillian Anne Gehring, Xiaohong Cheng, Xiangbing Zeng, Goran Ungar

Nature Communications

DOI

2018

Off targets toxicological investigation of anti-cancer tubulin inhibitors

A. Sabbagh, Yaxin Li

李亚馨

精选作品

期刊论文

Structure-Based Design and Free Energy Perturbation-Guided Synthesis of Novel VEGFR2 and HDAC Dual Inhibitors with Potent Antitumor Efficacy.

Design and Synthesis of Benzofuran-Pyrazole Hybrids as Dual TGF-βR1/VEGFR-2 Inhibitors for Anticancer Applications

Structure-based design, synthesis, and biological evaluation of benzofuran derivatives as dual TGF-βR1 and VEGFR2 inhibitors for potent antitumor therapy.

专业学位研究生培养模式改革研究与实践——以材料与化工专业硕士培养为例

食品科学与工程类专业无机化学课程教学改革探索

Triclinic Liquid Crystal of Counter-Rotating Squashed Double Helices in a Side-Chain Polymer

On the Mechanism of Soft Self‐Assembly from Melt: The Ubiquitous Heat Capacity Hump and Spontaneous Melt Chirality

Discovery of a urea-based hit compound as a novel inhibitor of transforming growth factor-β type 1 receptor: in silico and in vitro studies.

Special Issue “Drug Discovery and Application of New Technologies”

Thermotropic “Plumber's Nightmare”—A Tight Liquid Organic Double Framework

Highly Ordered Gyroid Nanostructured Polymers: Facile Fabrication by Polymerizable Pluronic Surfactants

Supertwisted Chiral Gyroid Mesophase in Chiral Rod‐Like Compounds

合成化学课程教学设计探索——以“碳负离子和碳正离子促进的碳链构建”为例

Integrated molecular modeling and dynamics approaches revealed the mechanism of selective inhibition of HDAC6/8

Enantiomers Self-Sort into Separate Counter-Twisted Ribbons of the Fddd Liquid Crystal─Antiferrochirality and Parachirality

Cover Feature: The Effect of Mesogenic Coronas on the Type and Anisotropy of Gold Nanoparticle Superlattices: When Can the Tail Wag the Dog? (Chem. Eur. J. 11/2023)

Computational Investigations of Coumarin Derivatives as Cyclin-Dependent Kinase 9 Inhibitors Using 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation.

The Effect of Mesogenic Coronas on the Type and Anisotropy of Gold Nanoparticle Superlattices: When Can the Tail Wag the Dog?

A case of antiferrochirality in a liquid crystal phase of counter-rotating staircases

Off targets toxicological investigation of anti-cancer tubulin inhibitors

研究方向