韩俊伟｜哈尔滨医科大学｜学者主页

2026

PathTIGR: A pathway topology-informed graph representation learning framework for immunotherapy response prediction.

Xiangmei Li, Yalan He, Jiashuo Wu, Zi Wang, Xilong Zhao, Yongbao Zhang, Bingyue Pan, Yujie Tang, Junwei Han

PubMed

DOI

2026

Interpretable graph deep learning framework for drug synergy prediction by integrating functional and clinical similarities

Jiyin Lai, Jiashuo Wu, Yalan He, Yongbao Zhang, Bin Li, Tingyu Shi, Junwei Han

npj Digital Medicine

DOI

2025

ChatRadio-Valuer: A Chat Large Language Model for Generalizable Radiology Impression Generation on Multi-Institution and Multi-System Data

Tianyang Zhong, Wei Zhao, Yu-Tong Zhang, Yi Pan, Peixin Dong, Zuowei Jiang, Han-Qi Jiang, Yi-Fan Zhou, Xiao-Yan Kui, You-Lan Shang, Lin Zhao, Li Yang, Yao-Nai Wei, Zhuoyi Li, Jiadong Zhang, Long-Tao Yang, Hao Chen, Huan Zhao, Yuxiao Liu, N. Zhu, Yiwei Li, Yisong Wang, Jiaqi Yao, Jiaqi Wang, Ying Zeng, Lei He, Chao Zheng, Zhixue Zhang, Ming Li, Zheng Liu, Hai-Xing Dai, Zihao Wu, Shu Zhang, Xiao-Long Cai, Xintao Hu, Shijie Zhao, Xi Jiang, Xin Zhang, Wei Liu, Xiang Li, Lei Guo, Dinggang Shen, Junwei Han, Tianming Liu, Jun Liu, Tuo Zhang

IEEE Transactions on Biomedical Engineering

DOI

2025

PathHDNN: a pathway hierarchical-informed deep neural network framework for predicting immunotherapy response and mechanism interpretation

Xiangmei Li, Bingyue Pan, Yalan He, Ziyi Wang, Yujie Tang, Yongbao Zhang, Liqiang Wang, Junwei Han

Genome Medicine

DOI

2025

DeepCCDS: Interpretable Deep Learning Framework for Predicting Cancer Cell Drug Sensitivity through Characterizing Cancer Driver Signals

Jiashuo Wu, Jiyin Lai, Xilong Zhao, Ziyi Wang, Yongbao Zhang, Liqiang Wang, Yinchun Su, Yalan He, Siyuan Li, Ying He Jiang, Junwei Han

Advanced Science

DOI

2025

ProgModule: A novel computational framework to identify mutation driver modules for predicting cancer prognosis and immunotherapy response

Xiangmei Li, Bingyue Pan, Xilong Zhao, Yinchun Su, Jiyin Lai, Siyuan Li, Yalan He, Jiashuo Wu, Junwei Han

Journal of Translational Medicine

DOI

2025

Knowledge-Based Artificial Intelligence System for Drug Prioritization

Yinchun Su, Jiashuo Wu, Xilong Zhao, Yue Hao, Ziyi Wang, Yongbao Zhang, Yujie Tang, Bingyue Pan, Guangyou Wang, Qingfei Kong, Junwei Han

Journal of Chemical Information and Modeling

DOI

2025

iPRISM: Intelligent Predicting Response to Cancer Immunotherapy through Systematic Modeling

Yinchun Su, Siyuan Li, Qian Wang, Bingyue Pan, Jiyin Lai, Guangyou Wang, Junwei Han, Qingfei Kong

Advanced Intelligent Systems

DOI

2024

CITMIC: Comprehensive Estimation of Cell Infiltration in Tumor Microenvironment based on Individualized Intercellular Crosstalk

Xilong Zhao, Jiashuo Wu, Jiyin Lai, Bingyue Pan, Miao Ji, Xiangmei Li, Yalan He, Junwei Han

Advanced Science

DOI

2024

IDMIR: identification of dysregulated miRNAs associated with disease based on a miRNA–miRNA interaction network constructed through gene expression data

Jiashuo Wu, Xilong Zhao, Yalan He, Bingyue Pan, Jiyin Lai, Miao Ji, Si‐Yuan Li, Junling Huang, Junwei Han

Briefings in Bioinformatics

DOI

2024

ssMutPA: single-sample mutation-based pathway analysis approach for cancer precision medicine

Yalan He, Jiyin Lai, Qian Wang, Bingyue Pan, Siyuan Li, Xilong Zhao, Ziyi Wang, Yongbao Zhang, Yujie Tang, Junwei Han

GigaScience

DOI

2023

PathwayTMB: A pathway-based tumor mutational burden analysis method for predicting the clinical outcome of cancer immunotherapy

Xiangmei Li, Yalan He, Ying Jiang, Bingyue Pan, Jiashuo Wu, Xilong Zhao, Junling Huang, Qian Wang, Liang Cheng, Junwei Han

Molecular Therapy — Nucleic Acids

DOI

2023

DTSEA: A network-based drug target set enrichment analysis method for drug repurposing against COVID-19

Yinchun Su, Jiashuo Wu, Xiangmei Li, Ji Li, Xilong Zhao, Bingyue Pan, Junling Huang, Qingfei Kong, Junwei Han

Computers in Biology and Medicine

DOI

2023

iATMEcell: identification of abnormal tumor microenvironment cells to predict the clinical outcomes in cancer based on cell–cell crosstalk network

Yuqi Sheng, Jiashuo Wu, Xiangmei Li, Jiayue Qiu, Ji Li, Qinyu Ge, Liang Cheng, Junwei Han

Briefings in Bioinformatics

DOI

2023

A pathway-based mutation signature to predict the clinical outcomes and response to CTLA-4 inhibitors in melanoma

Qian Wang, Xiangmei Li, Jiayue Qiu, Yalan He, Jiashuo Wu, Ji Li, Wei Liu, Junwei Han

Computational and Structural Biotechnology Journal

DOI

2022

DrugSim2DR: systematic prediction of drug functional similarities in the context of specific disease for drug repurposing

Jiashuo Wu, Ji Li, Yalan He, Junling Huang, Xilong Zhao, Bingyue Pan, Yahui Wang, Liang Cheng, Junwei Han

GigaScience

DOI

2022

Analysis of Tumor Microenvironment Heterogeneity among Breast Cancer Subtypes to Identify Subtype-Specific Signatures

Ji Li, Jiashuo Wu, Junwei Han

Genes

DOI

2022

Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy

Jiayue Qiu, Xiangmei Li, Yalan He, Qian Wang, Ji Li, Jiashuo Wu, Ying Jiang, Junwei Han

Journal of Translational Medicine

DOI

2022

PCLassoLog: A protein complex-based, group Lasso-logistic model for cancer classification and risk protein complex discovery

Wei Wang, Haiyan Yuan, Junwei Han, Wei Liu

Computational and Structural Biotechnology Journal

DOI

2022

Tumor Microenvironment Characterization in Breast Cancer Identifies Prognostic Pathway Signatures

Ji Li, Jiayue Qiu, Junwei Han, Xiangmei Li, Ying Jiang

Genes

DOI

2022

DRviaSPCN: a software package for drug repurposing in cancer via a subpathway crosstalk network

Jiashuo Wu, Xiangmei Li, Qian Wang, Junwei Han

Bioinformatics

DOI

2022

A novel pathway mutation perturbation score predicts the clinical outcomes of immunotherapy

Xiangmei Li, Yalan He, Jiashuo Wu, Jiayue Qiu, Ji Li, Qian Wang, Ying Jiang, Junwei Han

Briefings in Bioinformatics

DOI

2022

Pan‐cancer analysis reveals sex‐specific signatures in the tumor microenvironment

Junwei Han, Yang Yang, Xiangmei Li, Jiashuo Wu, Yuqi Sheng, Jiayue Qiu, Qian Wang, Ji Li, Yalan He, Liang Cheng, Yan Zhang

Molecular Oncology

DOI

2022

Development and Validation of a Three-Gene Prognostic Signature Based on Tumor Microenvironment for Gastric Cancer

Qian Wang, Xiangmei Li, Yahui Wang, Jiayue Qiu, Jiashuo Wu, Yalan He, Ji Li, Qingfei Kong, Junwei Han, Ying Jiang

Frontiers in Genetics

DOI

2021

Identification of Somatic Mutation-Driven Immune Cells by Integrating Genomic and Transcriptome Data

Ying Jiang, Baotong Zheng, Yang Yang, Xiangmei Li, Junwei Han

Frontiers in Cell and Developmental Biology

DOI

2021

SubtypeDrug: a software package for prioritization of candidate cancer subtype-specific drugs

Xudong Han, Qingfei Kong, Chonghui Liu, Liang Cheng, Junwei Han

Bioinformatics

DOI

2020

CNA2Subpathway: identification of dysregulated subpathway driven by copy number alterations in cancer

Yuqi Sheng, Ying Jiang, Yang Yang, Xiangmei Li, Jiayue Qiu, Jiashuo Wu, Liang Cheng, Junwei Han

Briefings in Bioinformatics

DOI

2020

MiRNA-Mediated Subpathway Identification and Network Module Analysis to Reveal Prognostic Markers in Human Pancreatic Cancer

Yuejuan Liu, Yuxia Cui, Xuefeng Bai, Chenchen Feng, Meng Li, Xiaole Han, Bo Ai, Jian Zhang, Xuecang Li, Junwei Han, Jiang Zhu, Yong Jiang, Qi Pan, Fan Wang, Mingcong Xu, Chunquan Li, Qiuyu Wang

Frontiers in Genetics

DOI

2020

LncSEA: a platform for long non-coding RNA related sets and enrichment analysis

Jiaxin Chen, Jian Zhang, Yu Gao, Yanyu Li, Chenchen Feng, Chao Song, Ziyu Ning, Xinyuan Zhou, Jianmei Zhao, Minghong Feng, Yuexin Zhang, Ling Wei, Qi Pan, Yong Jiang, Fengcui Qian, Junwei Han, Yongsan Yang, Qiuyu Wang, Chunquan Li

Nucleic Acids Research

DOI

2020

Inference of Subpathway Activity Profiles Reveals Metabolism Abnormal Subpathway Regions in Glioblastoma Multiforme

Xudong Han, Donghua Wang, Ping Zhao, Chonghui Liu, Yue Hao, Lulu Chang, Jiarui Zhao, Wei Zhao, Lili Mu, Jing‐Hua Wang, Hulun Li, Qingfei Kong, Junwei Han

Frontiers in Oncology

DOI

2019

System level characterization of small molecule drugs and their affected long noncoding RNAs

Haixiu Yang, Yanan Jiang, Yunpeng Zhang, Yanjun Xu, Chunlong Zhang, Junwei Han, Fei Su, Xiaoqi Liu, Kai Mi, Bing Liu, Desi Shang

Aging

DOI

2019

psSubpathway: a software package for flexible identification of phenotype-specific subpathways in cancer progression

Junwei Han, Xudong Han, Qingfei Kong, Liang Cheng

Bioinformatics

DOI

2019

Computational Methods for Identifying Similar Diseases

Liang Cheng, Hengqiang Zhao, Pingping Wang, Wenyang Zhou, Meng Luo, Tianxin Li, Junwei Han, Shu‐Lin Liu, Qinghua Jiang

Molecular Therapy — Nucleic Acids

DOI

2019

Prioritization of candidate cancer drugs based on a drug functional similarity network constructed by integrating pathway activities and drug activities

Jieyi Di, Baotong Zheng, Qingfei Kong, Ying Jiang, Siyao Liu, Yang Yang, Xudong Han, Yuqi Sheng, Yunpeng Zhang, Liang Cheng, Junwei Han

Molecular Oncology

DOI

2019

Identification of Cancer Dysfunctional Subpathways by Integrating DNA Methylation, Copy Number Variation, and Gene-Expression Data

Siyao Liu, Baotong Zheng, Yuqi Sheng, Qingfei Kong, Ying Jiang, Yang Yang, Xudong Han, Liang Cheng, Yunpeng Zhang, Junwei Han

Frontiers in Genetics

DOI

2018

Inference of patient‐specific subpathway activities reveals a functional signature associated with the prognosis of patients with breast cancer

Junwei Han, Siyao Liu, Ying Jiang, Chaohan Xu, Baotong Zheng, Minghao Jiang, Haixiu Yang, Fei Su, Chunquan Li, Yunpeng Zhang

Journal of Cellular and Molecular Medicine

DOI

2017

Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma

Chunquan Li, Qiuyu Wang, Jiquan Ma, Shengshu Shi, Xin Chen, Haixiu Yang, Junwei Han

Molecules

DOI

2017

The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases

Haixiu Yang, Desi Shang, Yanjun Xu, Chunlong Zhang, Feng Li, Zeguo Sun, Xinrui Shi, Yunpeng Zhang, Junwei Han, Fei Su, Chunquan Li, Xia Li

Scientific Reports

DOI

2017

LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method

Junwei Han, Siyao Liu, Zeguo Sun, Yunpeng Zhang, Fan Zhang, Chunlong Zhang, Desi Shang, Haixiu Yang, Fei Su, Yanjun Xu, Chunquan Li, Huan Ren, Xia Li

Scientific Reports

DOI

2016

Identification of novel prognostic indicators for triple-negative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data

Fan Zhang, Chunyan Ren, Hengqiang Zhao, Lei Yang, Fei Su, Ming‐Ming Zhou, Junwei Han, Eric A. Sobie, Martin J. Walsh

Oncotarget

DOI

2016

Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways

Chenchen Feng, Jian Zhang, Xuecang Li, Bo Ai, Junwei Han, Qiuyu Wang, Taiming Wei, Yong Jie Xu, Meng Li, Shang Li, Chao Song, Chunquan Li

Scientific Reports

DOI

2016

Subpathway-LNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNA-mRNA expression profile and pathway topologies

Xinrui Shi, Yanjun Xu, Chunlong Zhang, Feng Li, Zeguo Sun, Junwei Han, Fei Su, Yunpeng Zhang, Chunquan Li, Xia Li

Oncotarget

DOI

2016

Identification of a lncRNA involved functional module for esophageal cancer subtypes

Shang Li, Yanjun Xu, Zeguo Sun, Feng Li, Desi Shang, Chunlong Zhang, Xinrui Shi, Junwei Han, Fei Su, Haixiu Yang, Jianmei Zhao, Chao Song, Yunpeng Zhang, Chunquan Li, Xia Li

Molecular BioSystems

DOI

2016

MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs

Junwei Han, Siyao Liu, Yunpeng Zhang, Yanjun Xu, Ying Jiang, Chunlong Zhang, Chunquan Li, Xia Li

Oncotarget

DOI

2015

Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network

Qianlan Yao, Yanjun Xu, Haixiu Yang, Desi Shang, Chunlong Zhang, Yunpeng Zhang, Zeguo Sun, Xinrui Shi, Feng Li, Junwei Han, Fei Su, Chunquan Li, Xia Li

Scientific Reports

DOI

2015

Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies

Feng Li, Yanjun Xu, Yunpeng Zhang, Zeguo Sun, Junwei Han, Chunlong Zhang, Haixiu Yang, Desi Shang, Fei Su, Xinrui Shi, Shang Li, Chunquan Li, Xia Li

Oncotarget

DOI

2015

Topologically inferring pathway activity toward precise cancer classification via integrating genomic and metabolomic data: prostate cancer as a case

Wei Liu, Xuefeng Bai, Yuejuan Liu, Wei Wang, Junwei Han, Qiuyu Wang, Yanjun Xu, Chunlong Zhang, Shihua Zhang, Xuecang Li, Zhonggui Ren, Jian Zhang, Chunquan Li

Scientific Reports

DOI

2015

ESEA: Discovering the Dysregulated Pathways based on Edge Set Enrichment Analysis

Junwei Han, Xinrui Shi, Yunpeng Zhang, Yanjun Xu, Ying Jiang, Chunlong Zhang, Feng Li, Haixiu Yang, Desi Shang, Zeguo Sun, Fei Su, Chunquan Li, Xia Li

Scientific Reports

DOI

2015

Prioritization of rheumatoid arthritis risk subpathways based on global immune subpathway interaction network and random walk strategy

Wenhua Lv, Qiuyu Wang, He Chen, Yongshuai Jiang, Jiajia Zheng, Miao Shi, Yanjun Xu, Junwei Han, Chunquan Li, Ruijie Zhang

Molecular BioSystems

DOI

2015

Integrative analysis of lung development–cancer expression associations reveals the roles of signatures with inverse expression patterns

Chunlong Zhang, Chunquan Li, Yanjun Xu, Feng Li, Desi Shang, Xinmiao Yang, Junwei Han, Zeguo Sun, Yixue Li, Xia Li

Molecular BioSystems

DOI

2014

A novel dysregulated pathway-identification analysis based on global influence of within-pathway effects and crosstalk between pathways

Junwei Han, Chunquan Li, Haixiu Yang, Yanjun Xu, Chunlong Zhang, Jiquan Ma, Xinrui Shi, Wei Liu, Desi Shang, Qianlan Yao, Yunpeng Zhang, Fei Su, Feng Li, Xia Li

Journal of The Royal Society Interface

DOI

2014

A global view of network of lncRNAs and their binding proteins

Desi Shang, Haixiu Yang, Yanjun Xu, Qianlan Yao, Wenbin Zhou, Xinrui Shi, Junwei Han, Fei Su, Bin Su, Chunlong Zhang, Chunquan Li, Xia Li

Molecular BioSystems

DOI

2014

Prioritizing Candidate Disease Metabolites Based on Global Functional Relationships between Metabolites in the Context of Metabolic Pathways

Desi Shang, Chunquan Li, Qianlan Yao, Haixiu Yang, Yanjun Xu, Junwei Han, Jing Li, Fei Su, Yunpeng Zhang, Chunlong Zhang, Dongguo Li, Xia Li

PLoS ONE

DOI

2014

Identification of miRNA-Mediated Core Gene Module for Glioma Patient Prediction by Integrating High-Throughput miRNA, mRNA Expression and Pathway Structure

Chunlong Zhang, Chunquan Li, Jing Li, Junwei Han, Desi Shang, Yunpeng Zhang, Wei Zhang, Qianlan Yao, Lei Han, Yanjun Xu, Wei Yan, Zhaoshi Bao, Gan You, Tao Jiang, Chunsheng Kang, Xia Li

PLoS ONE

DOI

2014

The detection of risk pathways, regulated by miRNAs, via the integration of sample-matched miRNA-mRNA profiles and pathway structure

Jing Li, Chunquan Li, Junwei Han, Chunlong Zhang, Desi Shang, Qianlan Yao, Yunpeng Zhang, Yanjun Xu, Wei Liu, Meng Zhou, Haixiu Yang, Fei Su, Xia Li

Journal of Biomedical Informatics

DOI

2014

MPINet: Metabolite Pathway Identification via Coupling of Global Metabolite Network Structure and Metabolomic Profile

Feng Li, Yanjun Xu, Desi Shang, Haixiu Yang, Wei Liu, Junwei Han, Zeguo Sun, Qianlan Yao, Chunlong Zhang, Jiquan Ma, Fei Su, Feng Li, Xinrui Shi, Yunpeng Zhang, Jing Li, Qi Gu, Xia Li, Chunquan Li

BioMed Research International

DOI

2013

Dissection of miRNA-miRNA Interaction in Esophageal Squamous Cell Carcinoma

Bingli Wu, Chunquan Li, Pixian Zhang, Qianlan Yao, Jian‐Yi Wu, Junwei Han, Lian‐Di Liao, Yanjun Xu, Ruijun Lin, Dawei Xiao, Li‐Yan Xu, En‐Min Li, Xia Li

PLoS ONE

DOI

2013

Topologically inferring risk-active pathways toward precise cancer classification by directed random walk

Wei Liu, Chunquan Li, Yanjun Xu, Haixiu Yang, Qianlan Yao, Junwei Han, Desi Shang, Chunlong Zhang, Fei Su, Xiaoxi Li, Xiaoxi Li, Yun Xiao, Fan Zhang, Meng Dai, Xia Li, Xia Li

Bioinformatics

DOI

2013

Subpathway-GM: identification of metabolic subpathways via joint power of interesting genes and metabolites and their topologies within pathways

Chunquan Li, Junwei Han, Qianlan Yao, Chendan Zou, Yanjun Xu, Chunlong Zhang, Desi Shang, Lingyun Zhou, Chaoxia Zou, Zeguo Sun, Jing Li, Yunpeng Zhang, Haixiu Yang, Xu Gao, Xia Li

Nucleic Acids Research

DOI

2012

Characterizing the Network of Drugs and Their Affected Metabolic Subpathways

Chunquan Li, Desi Shang, Yan Wang, Jing Li, Junwei Han, Shuyuan Wang, Qianlan Yao, Yingying Wang, Yunpeng Zhang, Chunlong Zhang, Yanjun Xu, Wei Jiang, Xia Li

PLoS ONE

DOI

2012

Identifying disease related sub-pathways for analysis of genome-wide association studies

Chunquan Li, Junwei Han, Desi Shang, Jing Li, Yan Wang, Yingying Wang, Yunpeng Zhang, Qianlan Yao, Chunlong Zhang, Kongning Li, Xia Li

Gene

DOI

2011

The Implications of Relationships between Human Diseases and Metabolic Subpathways

Xia Li, Xia Li, Chunquan Li, Desi Shang, Jing Li, Junwei Han, Yingbo Miao, Yan Wang, Qianghu Wang, Wei Li, Chao Wu, Yunpeng Zhang, Xiang Li, Xiang Li, Qianlan Yao

PLoS ONE

DOI

2009

SubpathwayMiner: a software package for flexible identification of pathways

Chunquan Li, X. Li, Y. Miao, Q. Wang, Wei Jiang, Chun Di Xu, Jing Li, Junwei Han, F. Zhang, Binsheng Gong, L. Xu

Nucleic Acids Research

DOI

精选作品

期刊论文

PathTIGR: A pathway topology-informed graph representation learning framework for immunotherapy response prediction.

Interpretable graph deep learning framework for drug synergy prediction by integrating functional and clinical similarities

ChatRadio-Valuer: A Chat Large Language Model for Generalizable Radiology Impression Generation on Multi-Institution and Multi-System Data

PathHDNN: a pathway hierarchical-informed deep neural network framework for predicting immunotherapy response and mechanism interpretation

DeepCCDS: Interpretable Deep Learning Framework for Predicting Cancer Cell Drug Sensitivity through Characterizing Cancer Driver Signals

ProgModule: A novel computational framework to identify mutation driver modules for predicting cancer prognosis and immunotherapy response

Knowledge-Based Artificial Intelligence System for Drug Prioritization

iPRISM: Intelligent Predicting Response to Cancer Immunotherapy through Systematic Modeling

CITMIC: Comprehensive Estimation of Cell Infiltration in Tumor Microenvironment based on Individualized Intercellular Crosstalk

IDMIR: identification of dysregulated miRNAs associated with disease based on a miRNA–miRNA interaction network constructed through gene expression data

ssMutPA: single-sample mutation-based pathway analysis approach for cancer precision medicine

PathwayTMB: A pathway-based tumor mutational burden analysis method for predicting the clinical outcome of cancer immunotherapy

DTSEA: A network-based drug target set enrichment analysis method for drug repurposing against COVID-19

iATMEcell: identification of abnormal tumor microenvironment cells to predict the clinical outcomes in cancer based on cell–cell crosstalk network

A pathway-based mutation signature to predict the clinical outcomes and response to CTLA-4 inhibitors in melanoma

DrugSim2DR: systematic prediction of drug functional similarities in the context of specific disease for drug repurposing

Analysis of Tumor Microenvironment Heterogeneity among Breast Cancer Subtypes to Identify Subtype-Specific Signatures

Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy

PCLassoLog: A protein complex-based, group Lasso-logistic model for cancer classification and risk protein complex discovery

Tumor Microenvironment Characterization in Breast Cancer Identifies Prognostic Pathway Signatures

DRviaSPCN: a software package for drug repurposing in cancer via a subpathway crosstalk network

A novel pathway mutation perturbation score predicts the clinical outcomes of immunotherapy

Pan‐cancer analysis reveals sex‐specific signatures in the tumor microenvironment

Development and Validation of a Three-Gene Prognostic Signature Based on Tumor Microenvironment for Gastric Cancer

Identification of Somatic Mutation-Driven Immune Cells by Integrating Genomic and Transcriptome Data

SubtypeDrug: a software package for prioritization of candidate cancer subtype-specific drugs

CNA2Subpathway: identification of dysregulated subpathway driven by copy number alterations in cancer

MiRNA-Mediated Subpathway Identification and Network Module Analysis to Reveal Prognostic Markers in Human Pancreatic Cancer

LncSEA: a platform for long non-coding RNA related sets and enrichment analysis

Inference of Subpathway Activity Profiles Reveals Metabolism Abnormal Subpathway Regions in Glioblastoma Multiforme

System level characterization of small molecule drugs and their affected long noncoding RNAs

psSubpathway: a software package for flexible identification of phenotype-specific subpathways in cancer progression

Computational Methods for Identifying Similar Diseases

Prioritization of candidate cancer drugs based on a drug functional similarity network constructed by integrating pathway activities and drug activities

Identification of Cancer Dysfunctional Subpathways by Integrating DNA Methylation, Copy Number Variation, and Gene-Expression Data

Inference of patient‐specific subpathway activities reveals a functional signature associated with the prognosis of patients with breast cancer

Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma

The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases

LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method

Identification of novel prognostic indicators for triple-negative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data

Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways

Subpathway-LNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNA-mRNA expression profile and pathway topologies

Identification of a lncRNA involved functional module for esophageal cancer subtypes

MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs

Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network

Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies

Topologically inferring pathway activity toward precise cancer classification via integrating genomic and metabolomic data: prostate cancer as a case

ESEA: Discovering the Dysregulated Pathways based on Edge Set Enrichment Analysis

Prioritization of rheumatoid arthritis risk subpathways based on global immune subpathway interaction network and random walk strategy

Integrative analysis of lung development–cancer expression associations reveals the roles of signatures with inverse expression patterns

A novel dysregulated pathway-identification analysis based on global influence of within-pathway effects and crosstalk between pathways

A global view of network of lncRNAs and their binding proteins

Prioritizing Candidate Disease Metabolites Based on Global Functional Relationships between Metabolites in the Context of Metabolic Pathways

Identification of miRNA-Mediated Core Gene Module for Glioma Patient Prediction by Integrating High-Throughput miRNA, mRNA Expression and Pathway Structure

The detection of risk pathways, regulated by miRNAs, via the integration of sample-matched miRNA-mRNA profiles and pathway structure

MPINet: Metabolite Pathway Identification via Coupling of Global Metabolite Network Structure and Metabolomic Profile

Dissection of miRNA-miRNA Interaction in Esophageal Squamous Cell Carcinoma

Topologically inferring risk-active pathways toward precise cancer classification by directed random walk

Subpathway-GM: identification of metabolic subpathways via joint power of interesting genes and metabolites and their topologies within pathways

Characterizing the Network of Drugs and Their Affected Metabolic Subpathways

Identifying disease related sub-pathways for analysis of genome-wide association studies

The Implications of Relationships between Human Diseases and Metabolic Subpathways

SubpathwayMiner: a software package for flexible identification of pathways

预印本

Comprehensive Characterization of Tumor Microenvironment Differences in Cancer between Male and Female Patients

研究方向