秦娜｜河南中医药大学｜学者主页

2026

骨松强骨方入血成分分析及其抗骨质疏松症的作用机制预测和验证

陈汝娜，魏立伟，柴爽，张虹，滕军燕，秦娜

《世界中医药》

2026

中药和肠道菌群双向串扰在抗骨质疏松症中的作用

南懿琼，魏立伟，陈汝娜，郑旭霞，柴爽，有曼，张虹，秦娜

《中国中药杂志》

2026

[Role of bidirectional interaction between TCM and gut microbiota in treatment of osteoporosis].

Yi-Qiong Nan, Li-Wei Wei, Ru-Na Chen, Xu-Xia Zheng, Shuang Chai, Man-Mei You, Hong Zhang, Na Qin

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

DOI

2025

内质网应激与自噬交互作用在绝经后骨质疏松发病中的研究进展

陈汝娜，魏立伟，柴爽，张虹，秦娜

《中国药理学通报》

2024

基于肠道菌群及其代谢物探析骨松益骨方抗绝经后骨质疏松症

郑旭霞，魏立伟，谢艳，张虹，秦娜

《中医学报》

2024

基于内质网应激诱导的骨细胞凋亡探究骨松强骨方减轻去卵巢小鼠骨丢失的作用与机制

常宇博，潘博文，魏立伟，柴爽，郑旭霞，张虹，丁强，秦娜

《中国中药杂志》

2024

基于16S rRNA测序技术探讨骨松益骨方对去卵巢大鼠肠道菌群的影响

郑旭霞，柴爽，魏立伟，张虹，秦娜

《中国药理学通报》

2024

[Effect and mechanism of Gusong Qianggu Decoction on reducing bone loss in ovariectomized mice by targeting endoplasmic reticulum stress-induced apoptosis of osteocytes].

Yunhe Chang, Bo‐Wen Pan, Li-Wei Wei, Shuang Chai, Xu-Xia Zheng, Hong Zhang, Qiang Ding, Na Qin

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

DOI

2024

Luteolin rescues postmenopausal osteoporosis elicited by OVX through alleviating osteoblast pyroptosis via activating PI3K-AKT signaling.

Shuang Chai, Yan‐bing Yang, Li-Wei Wei, Yu-Ju Cao, Jiangtao Ma, Xu-Xia Zheng, Junyan Teng, Na Qin

Phytomedicine

DOI

2023

基于PI3K/Akt信号通路的骨松益骨方对去势大鼠的骨保护作用

郑旭霞，柴爽，魏立伟，秦娜

《中药新药与临床药理》

2023

骨松益骨方消补兼施治疗肾虚血瘀型绝经后骨质疏松症的组方分析

郑旭霞，柴爽，魏立伟，张虹，秦娜

《中医研究》

2023

Intra-articular administration of PLGA resveratrol sustained-release nanoparticles attenuates the development of rat osteoarthritis

Li-Wei Wei, Qingqing Pan, Junyan Teng, Hong Zhang, Na Qin

Materials Today Bio

DOI

2023

Resveratrol protects osteocytes against oxidative stress in ovariectomized rats through AMPK/JNK1-dependent pathway leading to promotion of autophagy and inhibition of apoptosis

Li-Wei Wei, Shuang Chai, Chen Yue, Hong Zhang, Ji-Tian Li, Na Qin

Cell Death Discovery

DOI

2022

仙灵骨葆胶囊治疗绝经后骨质疏松症的生物信息学和网络药理学分析和实验验证

柴爽，杨岩冰，马江涛，郭云鹏，滕军燕，秦娜，张虹

《世界中医药》

2022

大活络胶囊治疗类风湿性关节炎合并骨质疏松性脊柱陈旧性骨折腰痛的临床研究

秦娜

《中国中医药现代远程教育》

2021

桃仁膝康丸通过PI3K/AKT/mTOR信号通路激活软骨细胞自噬抗膝骨性关节炎的机制研究

秦娜，魏立伟，张虹

《中药药理与临床》

DOI

2019

Asperosaponin VI stimulates osteogenic differentiation of rat adipose-derived stem cells

Xingpo Ding, Wuyin Li, Dengshan Chen, Chuanwei Zhang, Lei Wang, Hong Zhang, Na Qin, Yongqiang Sun

Regenerative Therapy

DOI

2018

桃仁膝康丸激活软骨细胞自噬延缓骨性关节炎软骨退变的研究

秦娜，郭艳幸，魏立伟，张虹，罗石任，孙墨渊，孟璐

《中药新药与临床药理》

2018

桃仁膝康丸基于“温”“消”“补”治疗骨性关节炎的组方分析

罗石任，郭艳幸，张虹，魏立伟，刘培建，孟璐，刘晓红，秦娜

《中国中医基础医学杂志》

2017

Melatonin protects chondrocytes from impairment induced by glucocorticoids via NAD+‐dependent SIRT1

Wei Yang, Xiao-Min Kang, Na Qin, Feng Li, Xin-Xin Jin, Zheng-Min Ma, Z. Qian, Shu-Fang Wu

Steroids

DOI

2017

Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway.

Na Qin, Li-Wei Wei, Wuyin Li, Wei Yang, Litao Cai, Z. Qian, Shu-Fang Wu

Journal of Pharmacological Sciences

DOI

2016

Clock Gene Bmal1 Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1.

Wei Yang, Xiao-Min Kang, Jia-Li Liu, Hui-Xia Li, Zheng-Min Ma, Xin-Xin Jin, Z. Qian, Tianping Xie, Na Qin, Dong-Xu Feng, Wenjie Pan, Qian Chen, Hong-Zhi Sun, Shu-Fang Wu

Endocrinology

DOI

2014

[Effect of xuebijing injection on perioperative coagulation function and inflammatory reaction in senile patients receiving total hip arthroplasty].

Na Qin, Li-Wei Wei

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

2013

中药膝痛宁熏洗联合玻璃酸钠关节腔注射治疗膝骨性关节炎疗效观察

魏立伟，秦娜

《世界中医药》

2012

益气生骨颗粒剂的质量标准研究

谢艳，朱太咏，秦娜

《世界中医药》

2009

益气生骨注射液促进体外成肌细胞增殖作用的研究

谢艳，朱太咏，秦娜

《世界中医药》

秦娜

精选作品

期刊论文

骨松强骨方入血成分分析及其抗骨质疏松症的作用机制预测和验证

中药和肠道菌群双向串扰在抗骨质疏松症中的作用

[Role of bidirectional interaction between TCM and gut microbiota in treatment of osteoporosis].

内质网应激与自噬交互作用在绝经后骨质疏松发病中的研究进展

基于肠道菌群及其代谢物探析骨松益骨方抗绝经后骨质疏松症

基于内质网应激诱导的骨细胞凋亡探究骨松强骨方减轻去卵巢小鼠骨丢失的作用与机制

基于16S rRNA测序技术探讨骨松益骨方对去卵巢大鼠肠道菌群的影响

[Effect and mechanism of Gusong Qianggu Decoction on reducing bone loss in ovariectomized mice by targeting endoplasmic reticulum stress-induced apoptosis of osteocytes].

Luteolin rescues postmenopausal osteoporosis elicited by OVX through alleviating osteoblast pyroptosis via activating PI3K-AKT signaling.

基于PI3K/Akt信号通路的骨松益骨方对去势大鼠的骨保护作用

骨松益骨方消补兼施治疗肾虚血瘀型绝经后骨质疏松症的组方分析

Intra-articular administration of PLGA resveratrol sustained-release nanoparticles attenuates the development of rat osteoarthritis

Resveratrol protects osteocytes against oxidative stress in ovariectomized rats through AMPK/JNK1-dependent pathway leading to promotion of autophagy and inhibition of apoptosis

仙灵骨葆胶囊治疗绝经后骨质疏松症的生物信息学和网络药理学分析和实验验证

大活络胶囊治疗类风湿性关节炎合并骨质疏松性脊柱陈旧性骨折腰痛的临床研究

桃仁膝康丸通过PI3K/AKT/mTOR信号通路激活软骨细胞自噬抗膝骨性关节炎的机制研究

Asperosaponin VI stimulates osteogenic differentiation of rat adipose-derived stem cells

桃仁膝康丸激活软骨细胞自噬延缓骨性关节炎软骨退变的研究

桃仁膝康丸基于“温”“消”“补”治疗骨性关节炎的组方分析

Melatonin protects chondrocytes from impairment induced by glucocorticoids via NAD+‐dependent SIRT1

Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway.

Clock Gene Bmal1 Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1.

[Effect of xuebijing injection on perioperative coagulation function and inflammatory reaction in senile patients receiving total hip arthroplasty].

中药膝痛宁熏洗联合玻璃酸钠关节腔注射治疗膝骨性关节炎疗效观察

益气生骨颗粒剂的质量标准研究

益气生骨注射液促进体外成肌细胞增殖作用的研究

研究方向