孟萌｜南开大学｜学者主页

2026

新医科背景下药学三维融合式教学模式改革

张昱，尹永梅，孟萌，尚鲁庆

《中国现代教育装备》

2026

Lysosome-Bursting Calcium Carbonate Nanoparticles Amplify Immunogenic Cell Death via Synergistic Phototherapy and Calcium Overload for Immune Checkpoint Blockade

Fei-Fei Cui, Qi-Fan Wu, Ren-Jie Li, Meng-Fan Han, Chao-Kun Wang, Dai-Lin Feng, Ying-Rui Su, Yu-Ling Liu, Meng Meng, Jun Ye

Research

DOI

2026

An adjuvant codelivery nanosystem using Poria cocos polysaccharide for strengthened antitumor immunophototherapy.

Linxuan Shi, Shuo Wang, Cheng-Zhu Song, Fei-Fei Cui, Mei Zhang, Yiping Ma, Yue-Ping Bai, Zhaorui Song, Zili Zhang, Fan Zhang, Xing-Xin Yang, Meng Meng, Jie Yu

Colloids and Surfaces B: Biointerfaces

DOI

2026

cRGD-Functionalized Calcium Carbonate Nanoprobe for Enhanced NIR-II Fluorescence Imaging and Tumor-Targeted Navigation.

Le-Nan Wang, Linxuan Shi, Zhaorui Song, Qi-Fan Wu, Zi-Ye Chen, Fei-Fei Cui, Wenhong Dong, Meng Meng, Zili Zhang, Qi Xin, Zhen Cheng

Analytical Chemistry

DOI

2025

Dual-Modulation Design to Develop ER-Targeting NIR Pyroptosis Inducers with Type I PDT Efficacy and Amplified Antitumor Immunity.

Yan-ping Ma, Meng-Fan Han, Hanchen Zhu, Fei-Fei Cui, Yanqi Qiao, Yong-Mei Yin, Xiu-Jie Zhao, Rimo Xi, Meng Meng

Analytical Chemistry

DOI

2025

Controllable Self-Assembly of Amphiphilic Heptamethine Cyanines for Turn-On Fluorescence-Guided Tumor Phototherapy.

Yan-ping Ma, Meng-Fan Han, Ying-Rui Su, Yong-Mei Yin, Xiu-Jie Zhao, Rimo Xi, Meng Meng

Analytical Chemistry

DOI

2025

Ultrasensitive terahertz microfluidic biosensor integrated with tetrahedral DNA nanostructure for specific detection of live cancer cells

Peng Shen, Yun-Yun Ji, Xinmin Yue, Yi-Feng Li, Meng-Fan Han, Yan-ping Ma, Meng Meng, Fei Fan, Sheng-Jiang Chang

Sensors and actuators. B, Chemical

DOI

2025

Fabricating streptavidin-embedded metal-organic frameworks for noninvasive gene detection of Helicobacter pylori infection

Jiangyue Yu, Hongli Fu, Hanchen Zhu, Yaning Yang, Zeyan Di, Shuo Zhou, Yue Ao Tong, Changjun Men, Long Xu, Chunze Zhang, Rimo Xi, Meng Meng, Yao Chen

Biosensors and Bioelectronics

DOI

2024

Synergetic Pyroptosis with Apoptosis Improving Phototherapy of Mitochondria-Targeted Cyanines with Superior Photostability.

Xiu-Jie Zhao, Yan-ping Ma, Jianhao Di, Yanqi Qiao, Jie Yu, Yong-Mei Yin, Rimo Xi, Meng Meng

ACS Applied Materials and Interfaces

DOI

2024

High-speed and wide-field 3D Raman imaging using flower-like gap-enhanced Raman tags

Ming Chen, Jing-Fan Wang, Da Li, Bin Wang, Shuo Wang, Xing Zhao, Meng Meng

Applied Physics Letters

DOI

2024

Cascaded Nanozyme Based pH-Responsive Oxygenation for Targeted Eradication of Resistant Helicobacter Pylori.

Yue Tong, Qian Liu, Hongli Fu, Meng-Fan Han, Hanchen Zhu, Kun Yang, Le Xu, Meng Meng, Yong-Mei Yin, Rimo Xi

Small

DOI

2024

Template-Free Self-Assembly of Hollow Microtubular Covalent Organic Frameworks for Oral Delivery of Insulin.

Lihui Dai, Fang Wu, Yi Xiao, Qian Liu, Meng Meng, Rimo Xi, Yong-Mei Yin

ACS Applied Materials and Interfaces

DOI

2023

Reversible Recognition-Based Boronic Acid Probes for Glucose Detection in Live Cells and Zebrafish

Kai Wang, Ruixiao Zhang, Xiu-Jie Zhao, Yan-ping Ma, Lijuan Ren, Youxiao Ren, Gaofei Chen, Ding-Ming Ye, Jin-Fang Wu, Xin-Yuan Hu, Yuan-Qiang Guo, Rimo Xi, Meng Meng, Qingqiang Yao, Ping Li, Qixin Chen, Tony D. James

Journal of the American Chemical Society

DOI

2023

Mitochondria-Mediated HSP Inhibition Strategy for Enhanced Low-Temperature Photothermal Therapy.

Wenting Liu, Jianhao Di, Yan-ping Ma, Shuo Wang, Meng Meng, Yong-Mei Yin, Rimo Xi, Xiu-Jie Zhao

ACS Applied Materials and Interfaces

DOI

2023

MOF-gold core-satellite nanostructure based SERS platform for fentanyl detection in multiple complex samples

Xiaoya Li, Lu Sun, Bin Xu, Lihui Dai, Yi Xiao, Yumeng Ding, Qian Liu, Meng Meng, Rimo Xi, Lei Guo, Yong-Mei Yin

Sensors and actuators. B, Chemical

DOI

2023

A visual diagnostic detection of Helicobacter pylori and the gastric carcinoma-related virulence genes (cagA and vacA) by a fluorescent loop-mediated isothermal amplification (LAMP).

Bei Wang, Qi Gan, Yue Tong, Yanqi Qiao, Mengfan Han, Ruixiao Zhang, Q. Han, Chuanbing Li, Su Bai, Long Xu, Yong-Mei Yin, Chun-Ze Zhang, B. Munkhtsetseg, Xiu-Jie Zhao, Meng Meng, Rimo Xi

Talanta: The International Journal of Pure and Applied Analytical Chemistry

DOI

2023

An MMP-2 sensitive and reduction-responsive prodrug amphiphile for actively targeted therapy of cancer by hierarchical cleavage.

Xueni Zhang, Lihui Dai, Yumeng Ding, Qian Liu, Xiaoya Li, Mengting Liu, Meng Meng, Jie Pan, Rimo Xi, Yong-Mei Yin

Chemical Communications

DOI

2023

Hierarchical integration of DNA nanostructures and NanoGold onto a microchip facilitates covalent chemistry-mediated purification of circulating tumor cells in head and neck squamous cell carcinoma

Na Sun, Ceng Zhang, Jing Wang, Xinmin Yue, Hyoyong Kim, Ryan Y. Zhang, Hong-Tao Liu, Josephine Widjaja, Hubert Tang, Tiffany X. Zhang, Jinglei Ye, Audrey Qian, Chen-Song Liu, Alex Wu, Katharina Wang, M. Johanis, Peng Yang, Hong-Gang Liu, Meng Meng, Li Liang, R. Pei, W. Chai-Ho, Yazhen Zhu, Hsian-Rong Tseng

Nano Today

DOI

2023

A Dual‐Function Hemicyanine Material with Highly Efficient Photothermal and Photodynamic Effect Used for Tumor Therapy

Minglu Zhang, Shuo Wang, Yue-Ping Bai, Danyang Wang, Yu Fu, Zongyi Su, Guoqiang Zhang, Meng Meng, Fan Yu, Bing Wang, Hong-Zhen Jin, Wei Zhao

Advanced Healthcare Materials

DOI

2023

Mucus-Penetrating Nanoassembly as Potential Oral Phototherapeutic Formulation against Multi-Drug Resistant Helicobacter pylori Infection.

Yanqi Qiao, Meng-Fan Han, Hongli Fu, Ya-Ying Xu, Yue-Ping Bai, Shuo Wang, Jie Yu, Chang-Jun Men, Yong-Mei Yin, Xiu-Jie Zhao, Rimo Xi, Meng Meng

Small

DOI

2022

Phototherapy and Mechanism Exploration of Biofilm and Multidrug-Resistant Helicobacter pylori by Bacteria-Targeted NIR Photosensitizer.

Yanqi Qiao, Yan-ping Ma, Yue Tong, Wenting Liu, Shuo Wang, Ying Zheng, Chang-Jun Men, Jie Yu, Jie Pan, Dong Wan, Yong-Mei Yin, Xiu-Jie Zhao, Rimo Xi, Meng Meng

Small

DOI

2022

Reversing Tumor to “Hot”: A NIR Light-Triggered Carrier-Free Nanoplatform for Enhanced Tumor Penetration and Photo-induced Immunotherapy

Shuo Wang, Yue-Ping Bai, Dayuan Wang, Yunqian Zhai, Yanqi Qiao, Xiu-Jie Zhao, Yong-Mei Yin, Rimo Xi, Wei Wang, Wei Zhao, Meng Meng

Chemical Engineering Journal

DOI

2022

Size-Controllable DNA Origami-Stacked Gold Nanoparticles for Deep Tumor-Penetrating Therapy.

Dening Gu, Yanqi Qiao, Hongli Fu, Hong-Jie Zhao, Xinmin Yue, Shuo Wang, Yong-Mei Yin, Rimo Xi, Xiaoling Fu, Xiu-Jie Zhao, Meng Meng

ACS Applied Materials and Interfaces

DOI

2022

Synergistic Release of Photothermal Molecules from Nanocarriers Induced by Light and Hyperthermia Benefits Efficient Anticancer Phototherapy.

Xiu-Jie Zhao, Shuo Wang, Yan-ping Ma, Wenting Liu, Hong-Jie Zhao, Jianhao Di, Zhiwen Fan, Yong-Mei Yin, Ying Zheng, Rimo Xi, Meng Meng

Analytical Chemistry

DOI

2022

An isothiocyanate-functionalized self-immolative near-infrared fluorescence probe for cysteine sensing and bioimaging in living systems

Minglu Zhang, Shuo Wang, Yu Wan Fu, Meng Meng, Hongzhen Jin, Wei Guang Zhao

Sensors and Actuators B Chemical

DOI

2021

DNA-Based pH Nanosensor with Adjustable FRET Responses to Track Lysosomes and pH Fluctuations.

Xinmin Yue, Yanqi Qiao, Dening Gu, Rui Qi, Hong-Jie Zhao, Yong-Mei Yin, Wei Zhao, Rimo Xi, Meng Meng

Analytical Chemistry

DOI

2021

Dual functional molecule aided background-free SERS sensor for intracellular pH dynamic monitoring based on foldable DNA transition

Ying Zhang, Qian Liu, Mengting Liu, Xueni Zhang, Xiaoya Li, Lihui Dai, Meng Meng, Dingbin Liu, Yong-Mei Yin, Rimo Xi

Sensors and Actuators B: Chemical

DOI

2021

A Tumor-Targeting Near-Infrared Heptamethine Cyanine Photosensitizer with Twisted Molecular Structure for Enhanced Imaging-Guided Cancer Phototherapy.

Xiu-Jie Zhao, Hong-Jie Zhao, Shuo Wang, Zhiwen Fan, Yan Ma, Yong-Mei Yin, Wei Wang, Rimo Xi, Meng Meng

Journal of the American Chemical Society

DOI

2021

Fluorogenic Biosensors Constructed via Aggregation-induced Emission Based on Enzyme-catalyzed Coupling Reactions for Detection of Hydrogen Peroxide

Xiaogang Li, Wenxiu Yu, Hong-Jie Zhao, Zhiwen Fan, M. Xiao, Rimo Xi, Ying-Chun Xu, Meng Meng

Analytical Sciences

DOI

2021

Synthesis of Diboronic Acid-Based Fluorescent Probes for the Sensitive Detection of Glucose in Aqueous Media and Biological Matrices.

Kai Wang, Ruixiao Zhang, Xinmin Yue, Zheng Zhou, Lihuan Bai, Yue Tong, Bei Wang, Dening Gu, Shuo Wang, Yanqi Qiao, Qian Liu, Xue Xue, Yong-Mei Yin, Rimo Xi, Meng Meng

ACS Sensors

DOI

2021

A novel SERS biosensor for ultrasensitive detection of mercury(II) in complex biological samples

Qian Liu, Fang Wu, Huixia Di, Yingna Bi, Meng Meng, Dingbin Liu, Yong-Mei Yin, Rimo Xi

Sensors and Actuators B: Chemical

DOI

2020

Reliable FRET-ON imaging of telomerase in living cells by a tetrahedral DNA nanoprobe integrated with structure-switchable molecular beacon

Xinmin Yue, Yanqi Qiao, Dening Gu, Zi-Xuan Wu, Wen-Hui Zhao, Xiao-Yu Li, Yong-Mei Yin, Wei Zhao, De-Ming Kong, Rimo Xi, Meng Meng

Sensors and actuators. B, Chemical

DOI

2020

Improved cancer phototheranostic efficacy of hydrophobic IR780 via parenteral route by association with tetrahedral nanostructured DNA.

Shuo Wang, Zengyi Liu, Yue Tong, Yunqian Zhai, Xiu-Jie Zhao, Xinmin Yue, Yanqi Qiao, Yonghui Liu, Yong-Mei Yin, Rimo Xi, Wei Zhao, Meng Meng

Journal of Controlled Release

DOI

2020

AIEgens Conjugation Improves Photothermal Efficacy and NIR Imaging of Heptamethine Cyanine IR-780.

Xiu-Jie Zhao, Zhiwen Fan, Yanqi Qiao, Yun Chen, Shuo Wang, Xinmin Yue, T. Shen, Wenting Liu, Jie Yang, He-Qi Gao, Xuelin Zhan, Lu-Qing Shang, Yong-Mei Yin, Wei Zhao, Dan Ding, Rimo Xi, Meng Meng

ACS Applied Materials and Interfaces

DOI

2019

Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer

Jiantong Dong, Ryan Y. Zhang, Na Sun, Matthew D. Smalley, Zipeng Wu, Anqi Zhou, Shih-Jie Chou, Jen-Jan Yu, Peng Yang, Lirong Bao, D. Qi, Xinghong Tang, Patrick Tseng, Yue Hua, Di Xu, R. Kao, Meng Meng, Xi-Run Zheng, Ying Liu, Tatyana Vagner, Xiao-Shu Chai, Dong-Jing Zhou, Mengyuan Li, Shih-Hwa Chiou, Guang-Juan Zheng, D. Di Vizio, V. Agopian, E. Posadas, S. Jonas, Shin-Pon Ju, P. Weiss, Meiping Zhao, Hsian-Rong Tseng, Yazhen Zhu

ACS Applied Materials and Interfaces

DOI

2019

Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells

Jiantong Dong, Jen-Jan Yu, Juiy-uan Cheng, Ryan Y. Zhang, Meng Meng, Matthew D. Smalley, Pin-Jung Chen, Xinghong Tang, Patrick Tseng, Lirong Bao, Tzu‐Yang Huang, Dong-Jing Zhou, Yupin Liu, Xiao-Shu Chai, Hai-Bo Zhang, Anqi Zhou, V. Agopian, E. Posadas, J. Shyue, S. Jonas, P. Weiss, Mengyuan Li, Guang-Juan Zheng, Hsiao-Hua Yu, Meiping Zhao, Hsian-Rong Tseng, Yazhen Zhu

Science Advances

DOI

2018

The chemical redox modulated switch-on fluorescence of carbon dots for probing alkaline phosphatase and its application in an immunoassay

Pei Song, Qian Liu, Ying Zhang, Liu Wei, Meng Meng, Yong-Mei Yin, Rimo Xi

DOI

2018

Pyrophosphate-triggered intermolecular cross-linking of tetraphenylethylene molecules for multianalyte detection

Liu Wei, Wenxiu Yu, Xiao-Gang Li, Xiaoyong Zhao, Yu Zhang, Pei Song, Yong-Mei Yin, Rimo Xi, Meng Meng

DOI

2017

A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe(III) ions

Pei Song, Li-Sha Zhang, Hao Long, Meng Meng, Ting Liu, Yong-Mei Yin, Rimo Xi

DOI

2012

荧光偏振免疫分析方法快速检测沙拉沙星残留

宋佩，孟萌，Sergei A Eremin，张太昌，田溪，薛虎寅，张昱，尹永梅，郗日沫

《分析化学》

精选作品

期刊论文

新医科背景下药学三维融合式教学模式改革

Lysosome-Bursting Calcium Carbonate Nanoparticles Amplify Immunogenic Cell Death via Synergistic Phototherapy and Calcium Overload for Immune Checkpoint Blockade

An adjuvant codelivery nanosystem using Poria cocos polysaccharide for strengthened antitumor immunophototherapy.

cRGD-Functionalized Calcium Carbonate Nanoprobe for Enhanced NIR-II Fluorescence Imaging and Tumor-Targeted Navigation.

Dual-Modulation Design to Develop ER-Targeting NIR Pyroptosis Inducers with Type I PDT Efficacy and Amplified Antitumor Immunity.

Controllable Self-Assembly of Amphiphilic Heptamethine Cyanines for Turn-On Fluorescence-Guided Tumor Phototherapy.

Ultrasensitive terahertz microfluidic biosensor integrated with tetrahedral DNA nanostructure for specific detection of live cancer cells

Fabricating streptavidin-embedded metal-organic frameworks for noninvasive gene detection of Helicobacter pylori infection

Synergetic Pyroptosis with Apoptosis Improving Phototherapy of Mitochondria-Targeted Cyanines with Superior Photostability.

High-speed and wide-field 3D Raman imaging using flower-like gap-enhanced Raman tags

Cascaded Nanozyme Based pH-Responsive Oxygenation for Targeted Eradication of Resistant Helicobacter Pylori.

Template-Free Self-Assembly of Hollow Microtubular Covalent Organic Frameworks for Oral Delivery of Insulin.

Reversible Recognition-Based Boronic Acid Probes for Glucose Detection in Live Cells and Zebrafish

Mitochondria-Mediated HSP Inhibition Strategy for Enhanced Low-Temperature Photothermal Therapy.

MOF-gold core-satellite nanostructure based SERS platform for fentanyl detection in multiple complex samples

A visual diagnostic detection of Helicobacter pylori and the gastric carcinoma-related virulence genes (cagA and vacA) by a fluorescent loop-mediated isothermal amplification (LAMP).

An MMP-2 sensitive and reduction-responsive prodrug amphiphile for actively targeted therapy of cancer by hierarchical cleavage.

Hierarchical integration of DNA nanostructures and NanoGold onto a microchip facilitates covalent chemistry-mediated purification of circulating tumor cells in head and neck squamous cell carcinoma

A Dual‐Function Hemicyanine Material with Highly Efficient Photothermal and Photodynamic Effect Used for Tumor Therapy

Mucus-Penetrating Nanoassembly as Potential Oral Phototherapeutic Formulation against Multi-Drug Resistant Helicobacter pylori Infection.

Phototherapy and Mechanism Exploration of Biofilm and Multidrug-Resistant Helicobacter pylori by Bacteria-Targeted NIR Photosensitizer.

Reversing Tumor to “Hot”: A NIR Light-Triggered Carrier-Free Nanoplatform for Enhanced Tumor Penetration and Photo-induced Immunotherapy

Size-Controllable DNA Origami-Stacked Gold Nanoparticles for Deep Tumor-Penetrating Therapy.

Synergistic Release of Photothermal Molecules from Nanocarriers Induced by Light and Hyperthermia Benefits Efficient Anticancer Phototherapy.

An isothiocyanate-functionalized self-immolative near-infrared fluorescence probe for cysteine sensing and bioimaging in living systems

DNA-Based pH Nanosensor with Adjustable FRET Responses to Track Lysosomes and pH Fluctuations.

Dual functional molecule aided background-free SERS sensor for intracellular pH dynamic monitoring based on foldable DNA transition

A Tumor-Targeting Near-Infrared Heptamethine Cyanine Photosensitizer with Twisted Molecular Structure for Enhanced Imaging-Guided Cancer Phototherapy.

Fluorogenic Biosensors Constructed via Aggregation-induced Emission Based on Enzyme-catalyzed Coupling Reactions for Detection of Hydrogen Peroxide

Synthesis of Diboronic Acid-Based Fluorescent Probes for the Sensitive Detection of Glucose in Aqueous Media and Biological Matrices.

A novel SERS biosensor for ultrasensitive detection of mercury(II) in complex biological samples

Reliable FRET-ON imaging of telomerase in living cells by a tetrahedral DNA nanoprobe integrated with structure-switchable molecular beacon

Improved cancer phototheranostic efficacy of hydrophobic IR780 via parenteral route by association with tetrahedral nanostructured DNA.

AIEgens Conjugation Improves Photothermal Efficacy and NIR Imaging of Heptamethine Cyanine IR-780.

Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer

Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells

The chemical redox modulated switch-on fluorescence of carbon dots for probing alkaline phosphatase and its application in an immunoassay

Pyrophosphate-triggered intermolecular cross-linking of tetraphenylethylene molecules for multianalyte detection

A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe(III) ions

荧光偏振免疫分析方法快速检测沙拉沙星残留

会议论文

Photostable pH-Sensitive Near-Infrared Aggregation-Induced Emission Luminogen for Long-Term Mitochondrial Tracking

研究方向