肖芳

2026

The overlooked impact of polyether defoamer on sludge dewatering after anaerobic digestion

Water Research

DOI

2026

Prepregnancy Exposure to High Doses of Nanoplastics Triggers Persistent Vaginal Microbiome Dysbiosis to Induce Adverse Pregnant Outcomes

ACS Nano

DOI

2025

Association Between Heavy Metal Exposure and Central Nervous System Tumors: A Case-Control Study Using Single and Multi-Metal Models

Toxics

DOI

2025

Air Toxicity Surveillance across Thirteen Cities Using Rats

Environmental Science & Technology

DOI

2025

Corrigendum to “Blockage of ROS-ERK-DLP1 signaling and mitochondrial fission alleviates Cr (VI)-induced mitochondrial dysfunction in L02 hepatocyte” [Ecotoxicol. Environ. Saf. 186 (2019) 109749]

Ecotoxicology and Environmental Safety

DOI

2025

Why do microplastics aggravate cholestatic liver disease? The NLRP3-mediated intestinal barrier integrity damage matter

Environmental Pollution

DOI

2025

Ambient NO2 induces premature pulmonary senescence in rats: The role of the ROS-DRG1/CDK5 axis

Journal of Environmental Sciences

DOI

2024

The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component

Environmental Pollution

DOI

2023

重金属六价铬暴露后早衰肝细胞分泌表型中炎性成分的作用研究

《兰州大学学报(医学版)》

2023

Mechanism of NO2-induced migraine in rats: The exploration of the role of miR-653-3p/IGF1 axis

Journal of Hazardous Materials

DOI

2023

Ambient NO2 hinders neutrophil extracellular trap formation in rats: Assessment of the role of neutrophil autophagy

Journal of Hazardous Materials

DOI

2023

Curcumin attenuates diphenyl phosphate‐induced apoptosis in GC ‐2spd(ts) cells through activated autophagy via the Nrf2/P53 pathway

Environmental Toxicology

DOI

2023

The crosstalk between M1 macrophage polarization and energy metabolism disorder contributes to polystyrene nanoplastics-triggered testicular inflammation

Food and Chemical Toxicology

DOI

2022

Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-κB signaling pathway mediated by the DNA damage response

Ecotoxicology and Environmental Safety

DOI

2022

Ambient NO2 exposure induced cardiotoxicity associated with gut microbiome dysregulation and glycerophospholipid metabolism disruption

Ecotoxicology and Environmental Safety

DOI

2022

Effect of propiconazole on neutrophil extracellular traps formation: Assessing the role of autophagy

Food and Chemical Toxicology

DOI

2022

Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells

Food and Chemical Toxicology

DOI

2022

Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway

Environmental Science and Pollution Research

DOI

2021

Curcumin hinders PBDE-47-induced neutrophil extracellular traps release via Nrf2-associated ROS inhibition

Ecotoxicology and Environmental Safety

DOI

2021

Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway

Ecotoxicology and Environmental Safety

DOI

2021

ERK/p38/ROS burst responses to environmentally relevant concentrations of diphenyl phosphate-evoked neutrophil extracellular traps formation: Assessing the role of autophagy

Journal of Hazardous Materials

DOI

2021

Clusterin inhibits Cr(VI)-induced apoptosis via enhancing mitochondrial biogenesis through AKT-associated STAT3 activation in L02 hepatocytes

Ecotoxicology and Environmental Safety

DOI

2021

Role of Clusterin/NF-κB in the secretion of senescence-associated secretory phenotype in Cr(VI)-induced premature senescent L-02 hepatocytes

Ecotoxicology and Environmental Safety

DOI

2021

Polystyrene microplastics trigger hepatocyte apoptosis and abnormal glycolytic flux via ROS-driven calcium overload

Journal of Hazardous Materials

DOI

2021

The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence

Ecotoxicology and Environmental Safety

DOI

2021

Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium

Ecotoxicology and Environmental Safety

DOI

2021

Proteomic characteristics of PM2.5 -induced differentially expressed proteins in human renal tubular epithelial cells

Environmental Toxicology and Pharmacology

DOI

2020

Proteomic characteristics and identification of PM2.5-induced differentially expressed proteins in hepatocytes and c-Myc silenced hepatocytes

Ecotoxicology and Environmental Safety

DOI

2020

Clusterin alleviates Cr(VI)-induced mitochondrial apoptosis in L02 hepatocytes via inhibition of Ca2+-ROS-Drp1-mitochondrial fission axis

Ecotoxicology and Environmental Safety

DOI

2020

Keap1-Nrf2 pathway up-regulation via hydrogen sulfide mitigates polystyrene microplastics induced-hepatotoxic effects

Journal of Hazardous Materials

DOI

2020

Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity

Ecotoxicology and Environmental Safety

DOI

2020

In vivo respiratory toxicology of cooking oil fumes: Evidence, mechanisms and prevention

Journal of Hazardous Materials

DOI

2020

ROS-mediated miR-21-5p regulates the proliferation and apoptosis of Cr(VI)-exposed L02 hepatocytes via targeting PDCD4

Ecotoxicology and Environmental Safety

DOI

2020

Cellular and molecular mechanisms of xenobiotics-induced premature senescence

Toxicology Research

DOI

2020

Increased Mitochondrial Fragmentation Mediated by Dynamin-Related Protein 1 Contributes to Hexavalent Chromium-Induced Mitochondrial Respiratory Chain Complex I-Dependent Cytotoxicity

Toxics

DOI

2020

Alteration of DNA methylation induced by PM2.5 in human bronchial epithelial cells

Toxicology Research

DOI

2020

Cr(VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes

Biochemical Journal

DOI

2020

Metal Element Detection and Carcinogenicity Risk Assessment of PM2.5 Samples

Environmental Toxicology and Chemistry

DOI

2020

[Serum metabonomics study on Cr (Ⅵ ) subchronic exposure rats based on UPLC-Q-TOF-MS/MS platform].

PubMed

DOI

2019

Blockage of ROS-ERK-DLP1 signaling and mitochondrial fission alleviates Cr(VI)-induced mitochondrial dysfunction in L02 hepatocytes

Ecotoxicology and Environmental Safety

DOI

2019

Expression of Clusterin suppresses Cr(VI)-induced premature senescence through activation of PI3K/AKT pathway

Ecotoxicology and Environmental Safety

DOI

2018

Comparison of several commonly used detection indicators of cell senescence

Drug and Chemical Toxicology

DOI

2018

Role of mitochondrial damage in Cr(VI)‑induced endoplasmic reticulum stress in L‑02 hepatocytes

Molecular Medicine Reports

DOI

2018

Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes

Toxicology Research

DOI

2018

Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes

Metallomics

DOI

2018

The role of IP3R-SOCCs in Cr( vi )-induced cytosolic Ca2+ overload and apoptosis in L-02 hepatocytes

Toxicology Research

DOI

2018

Cr(VI)-Induced Autophagy Protects L-02 Hepatocytes from Apoptosis Through the ROS-AKT-mTOR Pathway

Cellular Physiology and Biochemistry

DOI

2017

几种常见细胞衰老检测指标的比较

《中国药理学与毒理学杂志》

2017

六价铬诱导的肝细胞线粒体依赖性凋亡中VDAC1的作用

《生态毒理学报》

2017

An evaluation of the protective role of vitamin C in reactive oxygen species-induced hepatotoxicity due to hexavalent chromium in vitro and in vivo

Journal of Occupational Medicine and Toxicology

DOI

2017

CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity

International Journal of Molecular Sciences

DOI

2017

Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway

Toxicology in Vitro

DOI

2017

In vitrocytotoxicity assessment of roundup (glyphosate) in L-02 hepatocytes

Journal of Environmental Science and Health Part B

DOI

2016

A Ca2+ chelator ameliorates chromium (VI)-induced hepatocyte L-02 injury via down-regulation of voltage-Dependent anion channel 1 (VDAC1) expression

Environmental Toxicology and Pharmacology

DOI

2016

Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes

Scientific Reports

DOI

2016

The role of STIM1 in the Cr( vi )-induced [Ca2+]iincrease and cell injury in L-02 hepatocytes

Metallomics

DOI

2015

生物样品中酸性鞘磷脂酶活性测定

《中国公共卫生》

2014

酸性鞘磷脂酶在二氧化硅致小鼠胚肺成纤维细胞纤维化体外模型中的作用

《中国药理学与毒理学杂志》

2014

Activation of Autophagy Protects Against ROS-Mediated Mitochondria-Dependent Apoptosis in L-02 Hepatocytes Induced by Cr(VI)

Cellular Physiology and Biochemistry

DOI

2014

Role of Mitochondrial Electron Transport Chain Dysfunction in Cr(VI)-Induced Cytotoxicity in L-02 Hepatocytes

Cellular Physiology and Biochemistry

DOI

2014

Desipramine Ameliorates Cr(VI)-Induced Hepatocellular Apoptosis via the Inhibition of Ceramide Channel Formation and Mitochondrial PTP Opening

Cellular Physiology and Biochemistry

DOI

2013

趋化因子与矽肺

《环境卫生学杂志》

2013

Time-order effects of vitamin C on hexavalent chromium-induced mitochondrial damage and DNA-protein crosslinks in cultured rat peripheral blood lymphocytes

Molecular Medicine Reports

DOI

2013

Reactive Oxygen Species Play a Central Role in Hexavalent Chromium-Induced Apoptosis in Hep3B Cells without the Functional Roles of p53 and Caspase-3

Cellular Physiology and Biochemistry

DOI

2012

Cr(Ⅵ)对肝细胞线粒体ATP酶6和ATP酶8基因表达的影响以及与能量代谢障碍的关系

《中国药理学与毒理学杂志》

2012

Cr（Ⅵ）诱导肝细胞线粒体呼吸链功能紊乱在细胞凋亡与早衰中的分子机制

《中南大学》

2012

Hexavalent chromium induces energy metabolism disturbance and p53-dependent cell cycle arrest via reactive oxygen species in L-02 hepatocytes

Molecular and Cellular Biochemistry

DOI

2012

Hexavalent chromium targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent caspase-3 activation in L-02 hepatocytes

International Journal of Molecular Medicine

DOI

2012

WITHDRAWN: Hexavalent chromium induces premature senescence through reactive oxygen species-mediated p53 pathway in L-02 hepatocytes

Biochemical and Biophysical Research Communications

DOI

2010

外源化学物干扰肝细胞线粒体ATP合成体系机制的研究进展

《中国药理学与毒理学杂志》

2023

六价铬通过DNA损伤反应介导的GATA4/NF-κκB信号通路诱导肝细胞早衰

《中国毒理学会第十次全国毒理学大会》

DOI

2023

内源性H2S通过调控Nrf2通路拮抗聚苯乙烯微塑料引发的肝毒性及机制研究

《中国毒理学会第十次全国毒理学大会论文集》

2017

SiO 2 致NIH3T3细胞纤维化与ASMase/Cer信号通路的关系及rAC的干预效应

《2017（第三届）毒性测试替代方法与转化毒理学（国际）学术研讨会》

2017

尘肺患者鞘磷脂类信号通路物质的表达及相关性研究

《2017（第三届）毒性测试替代方法与转化毒理学（国际）学术研讨会》