邓强｜复旦大学｜学者主页

2026

Radiological characteristics in coronal and sagittal planes and short-term postoperative outcomes in patients with lumbar disc herniation accompanied by sciatic scoliosis

Ji-Tao Yang, Xuyang Xie, Wei-Bin Sheng, Hai-Long Guo, Qiang Deng

Scientific Reports

DOI

2026

Comparison of the efficacy of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis: a retrospective comparative study

Ze-Kun Ma, Hao-Peng Luan, Kadeyanmu Abulimiti, Xuyang Xie, Jiyuan Tao, Ji-Tao Yang, Weibin Sheng, Qiang Deng

BMC Surgery

DOI

2025

Suppressing MASH fibrotic progression by blocking succinate-GPR91 signaling in HSCs

Li Xie, Hui Chen, Li Zhang, Yong‐Yu Yang, Yuan Zhou, Yue Ma, Chang Liu, Yu-Li Wang, Qin Zhu, Ya-Jun Yan, Jia Ding, Ning‐Ping Zhang, Qiang Deng, Xiuping Liu, Wei Jiang, Jian Wu

Hepatology

DOI

2025

Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein

Qian Qiu, Zihan He, Jing Liu, Huijun Xu, Jinyu Wang, Nannan Liu, Ning Kang, Shaokun Pan, Weien Yu, Zixiang Gao, Shimei Zhang, Yang Yang, Qiang Deng, Youhua Xie, Jiming Zhang, Zhongliang Shen

PLoS Pathogens

DOI

2025

Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection

Lin Yu, Hao Chang, Wentao Xie, Yuan Zheng, Le Yang, Qiong Wu, Fan Bu, Yuanfei Zhu, Youhua Xie, Guoyu Pan, Ke Lan, Qiang Deng

PLoS Pathogens

DOI

2025

Percutaneous Endoscopic Lumbar Discectomy for Single-Level Lumbar Disc Herniation With Sciatic Scoliosis in Adults

Ji-Tao Yang, Hao-Peng Luan, Xuyang Xie, Wei-Bin Sheng, Hai-Long Guo, Qiang Deng

Clinical Spine Surgery

DOI

2025

Effects of Puerarin on Blood Fluoride, Micro-CT Parameters and Bone Histomorphology in Rats with Fluorosis

Ji-Tao Yang, Xuyang Xie, Jialu Liu, Yu-Heng Fan, Qiang Deng

Indian Journal of Pharmaceutical Education and Research

DOI

2024

lncRNA在肌少-骨质疏松症中作用机制的研究进展

刘晏东，邓强，彭冉东

《中国病理生理杂志》

2024

Hedgehog信号通路在肌少-骨质疏松症中的肌骨共生作用

刘晏东，邓强，李中锋，彭冉东，王雨榕，李家明，马平怡，杜健强

《中国临床药理学杂志》

2024

调节性T细胞/Th17细胞平衡在肌骨衰减及重建中作用的研究进展

刘晏东，邓强，张彦军，李中锋，彭冉东，陈博

《细胞与分子免疫学杂志》

2024

间充质干细胞源性外泌体治疗脊髓损伤的研究进展

江朔轩，邓强，张彦军，郭铁峰，朱宝，王鹏，李家明，马平怡

《神经损伤与功能重建》

2024

铁死亡对椎间盘变性的影响机制研究进展

张彦军，刘晏东，邓强，郭铁峰，李家明，檀盛，罗林钊

《中国细胞生物学学报》

2024

Augmented epigenetic repression of hepatitis B virus covalently closed circular DNA by interferon-α and small-interfering RNA synergy

Kongying Hu, Wenjing Zai, Mingzhu Xu, Haiyu Wang, Xinluo Song, Chao Huang, Jiangxia Liu, Juan Chen, Qiang Deng, Zhenghong Yuan, Jieliang Chen

mBio

DOI

2024

Development of a Cell Culture Model for Inducible SARS-CoV-2 Replication

Xiaoyan Wang, Yuanfei Zhu, Qiong Wu, Nan Jiang, Youhua Xie, Qiang Deng

Viruses

DOI

2024

Hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression

Yu Su, Fan Bu, Yuanfei Zhu, Le Yang, Qiong Wu, Yuan Zheng, Jianjin Zhao, Lin Yu, Nan Jiang, Yongxiang Wang, Jian Wu, Youhua Xie, Xinxin Zhang, Yueqiu Gao, Ke Lan, Qiang Deng

《中国科学通报：英文版》

DOI

2024

Construction and efficacy testing of DNA vaccines containing HLA-A*02:01-restricted SARS-CoV-2 T-cell epitopes predicted by immunoinformatics

Dan Tan, Ning Kang, Yuanfei Zhu, Jia Hou, Hanqing Wang, Huijun Xu, Cheng Zu, Zixiang Gao, Mu Liu, Nannan Liu, Qiang Deng, Hongzhou Lu, Jing Liu, Youhua Xie

Acta Biochimica et Biophysica Sinica

DOI

2024

Non-proteolytic ubiquitination of HBx controls HBV replication

Xiangpeng Sheng, Yi Yang, Min Zhu, Linlin Zhou, Fang Zhu, Yuanfei Zhu, Siying Dong, Hui Kong, Honghua Wang, Jiang Ji, Mingyue Wan, Mingyang Feng, Qiang Deng, Yumin Xu, Qing You, Ronggui Hu

Virologica Sinica

DOI

2024

Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus

Zhongliang Shen, Shenyan Zhang, Zixiang Gao, Xueping Yu, Jinyu Wang, Shaokun Pan, Ning Kang, Nannan Liu, Huijun Xu, Mu Liu, Yang Yang, Qiang Deng, Jing Liu, Youhua Xie, Jiming Zhang

Journal of Virology

DOI

2024

TGF-β2-modulating Anti-apoptosis Effect of Osteoblasts by Sodium Fluoride

Ji-Tao Yang, Jialu Liu, Xuyang Xie, Qiang Deng

Indian Journal of Pharmaceutical Education and Research

DOI

2024

Surgical strategy of ankylosing spondylitis combined with cervical fracture: a retrospective study.

Hao-Peng Luan, Xuyang Xie, Weibin Sheng, Qiang Deng

Asian Journal of Surgery

DOI

2024

Efficacy and safety of ultrasonic bone curette and high-speed drill in cervical expansive open-door laminoplasty: A systematic review and meta-analysis.

Hao-Peng Luan, Cong Peng, H. Jia, Qiang Deng

Asian Journal of Surgery

DOI

2023

外泌体在肌骨衰减性疾病中的作用

刘晏东，张彦军，邓强，李中锋，彭冉东

《中国细胞生物学学报》

2023

Canocapavir Is a Novel Capsid Assembly Modulator Inducing a Conformational Change of the Linker Region of HBV Core Protein

Yuan Zheng, Le Yang, Lin Yu, Yuanfei Zhu, Yang Wu, Zhijun Zhang, Tian Xia, Qiang Deng

Viruses

DOI

2022

人PKCα蛋白结构和功能的生物信息学分析

江岚，邓强，龙鼎新

《中南医学科学杂志》

2022

Interleukin-33 mediates both immune-related and non-immune-related inhibitory effects against hepatitis B virus

Zixiang Gao, Zhongliang Shen, Jingwen Wu, Yingying Song, Nannan Liu, Qiang Deng, Youhua Xie, Jing Liu

Antiviral Research

DOI

2022

Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

Xiaoyu Sun, Chunyan Yi, Yuanfei Zhu, Longfei Ding, Shuai Xia, Xingchen Chen, Mu Liu, Chenjian Gu, Xiaoxia Lü, Yadong Fu, Shuangfeng Chen, Tianlong Zhang, Yaguang Zhang, Zhuo Ru Yang, Liyan Ma, Wangpeng Gu, Gaowei Hu, Shujuan Du, Renhong Yan, Weihui Fu, Songhua Yuan, Chenli Qiu, Chen Zhao, Xiaoyan Zhang, Yonghui He, Aidong Qu, Xu Zhou, Xiuling Li, Gary Wong, Qiang Deng, Qiang Zhou, Hongzhou Lu, Zhiyang Ling, Jianping Ding, Lu Lu, Jianqing Xu, Youhua Xie, Bing Sun

Nature Microbiology

DOI

2022

Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection

Yingying Song, Shuyu Shou, Huimin Guo, Zixiang Gao, Nannan Liu, Yang� Yang, Feifei Wang, Qiang Deng, Jing Liu, Youhua Xie

Virologica Sinica

DOI

2022

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

Cheng Li, Wuqiang Zhan, Zhenlin Yang, Chao Tu, Gaowei Hu, Xiang Zhang, Wenping Song, Shujuan Du, Yuanfei Zhu, Keke Huang, Yu Kong, Meng Zhang, Qiyu Mao, Xiaodan Gu, Yi Zhang, Youhua Xie, Qiang Deng, Yuanlin Song, Zhenguo Chen, Lu Lu, Shibo Jiang, Yanling Wu, Lei Sun, Tianlei Ying

Cell

DOI

2022

High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein

Zhongliang Shen, Jingwen Wu, Zixiang Gao, Shenyan Zhang, Jingwen Chen, Jingjing He, Yifei Guo, Qiang Deng, Youhua Xie, Jing Liu, Jiming Zhang

Nucleic Acids Research

DOI

2021

Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein

Shiqi Xu, Yifan Wang, Yanxing Wang, Chao Zhang, Hong Qin, Chenjian Gu, Rong Xu, Tingfeng Wang, Yong Ping Yang, Jinkai Zang, Yu Zhou, Zuyang Li, Qixing Liu, Bingjie Zhou, Lulu Bai, Yuanfei Zhu, Qiang Deng, Haikun Wang, Dimitri Lavillette, Gary Wong, Youhua Xie, Yao Cong, Zhong Wei Huang

Emerging Microbes & Infections

DOI

2021

HBV covalently closed circular DNA minichromosomes in distinct epigenetic transcriptional states differ in their vulnerability to damage

Yang Wang, Yumeng Li, Wenjing Zai, Kongying Hu, Yuanfei Zhu, Qiang Deng, Min Wu, Yaming Li, Jieliang Chen, Zhenghong Yuan

Hepatology

DOI

2021

Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV

Shilin Yuan, Guanghong Liao, Menghuan Zhang, Yuanfei Zhu, Weidi Xiao, Kun Wang, Chuanyin Li, Caiwei Jia, Na Sun, Axel Karl Walch, Daming Gao, Ping Xu, Qiang Deng, Jian Zhang, He Wang, Ronggui Hu

Cell Discovery

DOI

2021

Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection

Jinkai Zang, Yuanfei Zhu, Yu Zhou, Chenjian Gu, Yufang Yi, Shuxia Wang, Shiqi Xu, Gaowei Hu, Shujuan Du, Yannan Yin, Yalei Wang, Yong Ping Yang, Xueyang Zhang, Haikun Wang, Feifei Yin, Chao Zhang, Qiang Deng, Youhua Xie, Zhong Wei Huang

Cell Discovery

DOI

2021

Lost Small Envelope Protein Expression from Naturally Occurring PreS1 Deletion Mutants of Hepatitis B Virus Is Often Accompanied by Increased HBx and Core Protein Expression as Well as Genome Replication

Shuwen Fu, Jing Zhang, Quan Yuan, Qianru Wang, Qiang Deng, Jisu Li, Ningshao Xia, Yongxiang Wang, Yumei Wen, Shuping Tong

Journal of Virology

DOI

2021

Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection

Shilin Yuan, Guanghong Liao, Menghuan Zhang, Yuanfei Zhu, Kun Wang, Weidi Xiao, Caiwei Jia, Minhui Dong, Na Sun, Axel Karl Walch, Ping Xu, Jiming Zhang, Qiang Deng, Ronggui Hu

Journal of Hepatology

DOI

2021

Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections

Chao Zhang, Yifan Wang, Yuanfei Zhu, Caixuan Liu, Chenjian Gu, Shiqi Xu, Yalei Wang, Yu Zhou, Yanxing Wang, Wenyu Han, Xiaoyu Hong, Yong Ping Yang, Xueyang Zhang, Tingfeng Wang, Cong Xu, Hong Qin, Shutian Wang, Qiaoyu Zhao, Weihua Qiao, Jinkai Zang, Liangliang Kong, Fangfang Wang, Haikun Wang, Di Qu, Dimitri Lavillette, Hong Tang, Qiang Deng, Youhua Xie, Yao Cong, Zhong Wei Huang

Nature Communications

DOI

2020

Protoporphyrin IX and verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2

Chenjian Gu, Yang Wu, Huimin Guo, Yuanfei Zhu, Wei Xu, Yuyan Wang, Yu Zhou, Zhiping Sun, Xia Cai, Yutang Li, Jing Liu, Zhong Wei Huang, Zhenghong Yuan, Rong Zhang, Qiang Deng, Di Qu, Youhua Xie

《中国科学通报：英文版》

DOI

2020

Immunomodulatory and Antiviral Activity of Metformin and Its Potential Implications in Treating Coronavirus Disease 2019 and Lung Injury

Xianyang Chen, Huifang Guo, Qiu Li, Chengdong Zhang, Qiang Deng, Qibin Leng

Frontiers in Immunology

DOI

2020

Restriction of exogenous DNA expression by SAMHD1

Chenjian Gu, Lijun Ming, Yili Fang, Xuejing Liu, Junqi Zhang, Gennadiy Zelinskyy, Qiang Deng, Jing Liu, Youhua Xie

《中国科学通报：英文版》

DOI

2020

Yin-Yang 1 and HBx protein activate HBV transcription by mediating the spatial interaction of cccDNA minichromosome with cellular chromosome 19p13.11

Congle Shen, Xiaoyu Feng, Tianhao Mao, Danli Yang, Jun Zou, Xiaobin Zao, Qiang Deng, Xiangmei Chen, Fengmin Lu

Emerging Microbes & Infections

DOI

2020

Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement

Jinkai Zang, Chenjian Gu, Bingjie Zhou, Chao Zhang, Yong Ping Yang, Shiqi Xu, Xueyang Zhang, Yu Zhou, Lulu Bai, Yang Wu, Zhiping Sun, Rong Zhang, Qiang Deng, Zhenghong Yuan, Hong Tang, Di Qu, Dimitri Lavillette, Youhua Xie, Zhong Wei Huang

Cell Discovery

DOI

2019

细辛脑的临床前毒性研究进展

张梦林，林娜，邓强，张汉桥，刘健，马卓，苏江涛

《毒理学杂志》

DOI

2019

“益气养阴、逐瘀化痰”法治疗老年性脊柱结核的思路初探

李军杰，邓强，张彦军，李中锋，彭冉东，唐兰兰，徐浩军

《中国中医基础医学杂志》

DOI

2019

IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse models

Zhongliang Shen, Jing Liu, Jingwen Wu, Yuanfei Zhu, Gaiyun Li, Jun Wang, Mengjun Luo, Qiang Deng, Jiming Zhang, Youhua Xie

Theranostics

DOI

2017

Recombinant covalently closed circular DNA of hepatitis B virus induces long‐term viral persistence with chronic hepatitis in a mouse model

Gaiyun Li, Yuanfei Zhu, Dianhui Shao, Hao Chang, Xiaoming Zhang, Dongming Zhou, Yueqiu Gao, Ke Lan, Qiang Deng

Hepatology

DOI

2015

中药熏蒸联合推拿治疗腰椎间盘突出症的临床效果

李中锋，邓强，张彦军，陈文，韩宪富

《现代生物医学进展》

1999

诱生型一氧化氮合酶与脑缺血后期损伤

邓强，徐洪，朱东亚

《生命科学》

精选作品

期刊论文

Radiological characteristics in coronal and sagittal planes and short-term postoperative outcomes in patients with lumbar disc herniation accompanied by sciatic scoliosis

Comparison of the efficacy of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis: a retrospective comparative study

Suppressing MASH fibrotic progression by blocking succinate-GPR91 signaling in HSCs

Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein

Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection

Percutaneous Endoscopic Lumbar Discectomy for Single-Level Lumbar Disc Herniation With Sciatic Scoliosis in Adults

Effects of Puerarin on Blood Fluoride, Micro-CT Parameters and Bone Histomorphology in Rats with Fluorosis

lncRNA在肌少-骨质疏松症中作用机制的研究进展

Hedgehog信号通路在肌少-骨质疏松症中的肌骨共生作用

调节性T细胞/Th17细胞平衡在肌骨衰减及重建中作用的研究进展

间充质干细胞源性外泌体治疗脊髓损伤的研究进展

铁死亡对椎间盘变性的影响机制研究进展

Augmented epigenetic repression of hepatitis B virus covalently closed circular DNA by interferon-α and small-interfering RNA synergy

Development of a Cell Culture Model for Inducible SARS-CoV-2 Replication

Hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression

Construction and efficacy testing of DNA vaccines containing HLA-A*02:01-restricted SARS-CoV-2 T-cell epitopes predicted by immunoinformatics

Non-proteolytic ubiquitination of HBx controls HBV replication

Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus

TGF-β2-modulating Anti-apoptosis Effect of Osteoblasts by Sodium Fluoride

Surgical strategy of ankylosing spondylitis combined with cervical fracture: a retrospective study.

Efficacy and safety of ultrasonic bone curette and high-speed drill in cervical expansive open-door laminoplasty: A systematic review and meta-analysis.

外泌体在肌骨衰减性疾病中的作用

Canocapavir Is a Novel Capsid Assembly Modulator Inducing a Conformational Change of the Linker Region of HBV Core Protein

人PKCα蛋白结构和功能的生物信息学分析

Interleukin-33 mediates both immune-related and non-immune-related inhibitory effects against hepatitis B virus

Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein

Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein

HBV covalently closed circular DNA minichromosomes in distinct epigenetic transcriptional states differ in their vulnerability to damage

Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV

Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection

Lost Small Envelope Protein Expression from Naturally Occurring PreS1 Deletion Mutants of Hepatitis B Virus Is Often Accompanied by Increased HBx and Core Protein Expression as Well as Genome Replication

Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection

Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections

Protoporphyrin IX and verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2

Immunomodulatory and Antiviral Activity of Metformin and Its Potential Implications in Treating Coronavirus Disease 2019 and Lung Injury

Restriction of exogenous DNA expression by SAMHD1

Yin-Yang 1 and HBx protein activate HBV transcription by mediating the spatial interaction of cccDNA minichromosome with cellular chromosome 19p13.11

Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement

细辛脑的临床前毒性研究进展

“益气养阴、逐瘀化痰”法治疗老年性脊柱结核的思路初探

IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse models

Recombinant covalently closed circular DNA of hepatitis B virus induces long‐term viral persistence with chronic hepatitis in a mouse model

中药熏蒸联合推拿治疗腰椎间盘突出症的临床效果

诱生型一氧化氮合酶与脑缺血后期损伤

中西医结合脊柱疾病治疗学

会议论文

Calpain在TOCP抑制SK-N-SH细胞自噬中的作用及机制研究

IP 3 R在TOCP调节的细胞自噬中的作用与机制

DC细胞TLR2/TLR4的表达与慢性HBV感染相关性研究

Blockade of Mtor in Innate Immune System Represents an Effective Strategy to Boost TLR-Induced Thl Response for HBV and HCV Vaccine

P91024的药理学研究

iNOS介导脑缺血损伤及iNOS抑制剂研究

书籍章节

The Cre/loxP-Based Recombinant HBV cccDNA System In Vitro and In Vivo