李珊珊｜湖北大学｜学者主页

2026

Author Correction: The SESAME complex regulates cell senescence through the generation of acetyl-CoA

Wanping Chen, Xilan Yu, Yinsheng Wu, Jie Tang, Qi Yu, Xiaodong Lv, Zitong Zha, 胡必成, Xin Li, Jianguo Chen, Lixin Ma, Jerry L. Workman, Shanshan Li

Nature Metabolism

DOI

2026

Local acetyl-CoA metabolism and acetate recycling as epigenetic regulators of chromatin dynamics

Jueun Kim, Fei He, Shanshan Li, Jung‐Shin Lee

FEMS Yeast Research

DOI

2025

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Yinsheng Wu, Xinlin Xu, Tong Yue, Min Wang, Feng Ge, Min Yi Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li

Advanced Science

DOI

2025

PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1

Wenjing Dai, Qi Yu, Rui Ma, Zhu Zheng, Lingling Hong, Yuqing Qi, Fei He, Min Wang, Feng Ge, Xilan Yu, Shanshan Li

Nature Communications

DOI

2025

Author Correction: Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy

Qi Yu, Xuanyunjing Gong, Tong Yue, Min Wang, Kai Duan, Xinyu Zhang, Feng Ge, Xilan Yu, Shanshan Li

Nature Communications

DOI

2024

Specific regulation of epigenome landscape by metabolic enzymes and metabolites

Xilan Yu, Shanshan Li

Biological reviews/Biological reviews of the Cambridge Philosophical Society

DOI

2023

Cla4 phosphorylates histone methyltransferase Set1 to prevent its degradation by the APC/C Cdh1 complex

Xuanyunjing Gong, Shanshan Wang, Qi Yu, Min Wang, Feng Ge, Shanshan Li, Xilan Yu

Science Advances

DOI

2023

Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability

Xinyu Zhang, Qi Yu, Yinsheng Wu, Yuan Zhang, Yi He, Rongsha Wang, Xilan Yu, Shanshan Li

Cell Discovery

DOI

2023

Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence

Yinsheng Wu, Lixu Tang, Han Huang, Qi Yu, Bicheng Hu, Gang Wang, Feng Ge, Tailang Yin, Shanshan Li, Xilan Yu

Nature Communications

DOI

2023

The TORC1 activates Rpd3L complex to deacetylate Ino80 and H2A.Z and repress autophagy

Xin Li, Qianyun Mei, Qi Yu, Min Wang, Fei He, Duncheng Xiao, Huan Liu, Feng Ge, Xilan Yu, Shanshan Li

Science Advances

DOI

2023

Transcriptional regulation of autophagy by chromatin remodeling complex and histone variant

Xin Li, Shanshan Wang, Xilan Yu, Shanshan Li

Autophagy

DOI

2022

SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing

Fei He, Qi Yu, Min Wang, Rongsha Wang, Xuanyunjing Gong, Feng Ge, Xilan Yu, Shanshan Li

Nature Communications

DOI

2022

Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy

Qi Yu, Xuanyunjing Gong, Tong Yue, Min Wang, Kai Duan, Xinyu Zhang, Feng Ge, Xilan Yu, Shanshan Li

Nature Communications

DOI

2022

Acetylation-dependent SAGA complex dimerization promotes nucleosome acetylation and gene transcription

Junhua Huang, Wenjing Dai, Duncheng Xiao, Qian Xiong, Cuifang Liu, Jie Hu, Feng Ge, Xilan Yu, Shanshan Li

Nature Structural & Molecular Biology

DOI

2021

妊娠期运动降低SHR子代血压的钙通道CACNA1C基因DNA甲基化机制

李珊珊，陈渝，张严焱，曾凡星，石丽君

《北京体育大学学报》，Vol. 44, No. 4

下载原文

2021

The SESAME complex regulates cell senescence through the generation of acetyl-CoA

Wanping Chen, Xilan Yu, Yinsheng Wu, Jie Tang, Qi Yu, Xiaodong Lv, Zitong Zha, Bicheng Hu, Xin Li, Jianguo Chen, Lixin Ma, Jerry L. Workman, Shanshan Li

Nature Metabolism

DOI

2021

Interplay Between Glucose Metabolism and Chromatin Modifications in Cancer

Rui Ma, Yinsheng Wu, Shanshan Li, Xilan Yu

Frontiers in Cell and Developmental Biology

DOI

2021

Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation

Shihao Zhang, Xilan Yu, Yuan Zhang, Xiangyan Xue, Qi Yu, Zitong Zha, Madelaine Gogol, Jerry L. Workman, Shanshan Li

Nature Communications

DOI

2020

Histone acetyltransferase Gcn5 regulates gene expression by promoting the transcription of histone methyltransferase SET1

Xuanyunjing Gong, Qi Yu, Kai Duan, Tong Yue, Xinyu Zhang, Qianyun Mei, Li Lü, Xilan Yu, Shanshan Li

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

DOI

2019

Exogenous pyruvate represses histone gene expression and inhibits cancer cell proliferation via the NAMPT–NAD+–SIRT1 pathway

Rui Ma, Yinsheng Wu, Yansheng Zhai, Bicheng Hu, Wei Ma, Wenqiang Yang, Qi Yu, Zhen Chen, Jerry L. Workman, Xilan Yu, Shanshan Li

Nucleic Acids Research

DOI

2019

Set1-catalyzed H3K4 trimethylation antagonizes the HIR/Asf1/Rtt106 repressor complex to promote histone gene expression and chronological life span

Qianyun Mei, Chen Xu, Madelaine Gogol, Jie Tang, Wanping Chen, Xilan Yu, Jerry L. Workman, Shanshan Li

Nucleic Acids Research

DOI

2019

Glycolysis regulates gene expression by promoting the crosstalk between H3K4 trimethylation and H3K14 acetylation in Saccharomyces cerevisiae

Yinsheng Wu, Shihao Zhang, Xuanyunjing Gong, Qi Yu, Yuan Zhang, Mingdan Luo, Xianhua Zhang, Jerry L. Workman, Xilan Yu, Shanshan Li

Journal of genetics and genomics/Journal of Genetics and Genomics

DOI

2018

运动改善高血压肠系膜动脉LTCC和BKCa通道功能的表观遗传调控机制

张严焱，徐召霞，陈渝，李珊珊，石丽君

《体育科学》，Vol. 38, No. 11

下载原文

2018

Reciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in Cancer

Xilan Yu, Rui Ma, Yinsheng Wu, Yansheng Zhai, Shanshan Li

Frontiers in Genetics

DOI

2017

Regulation of DNA replication-coupled histone gene expression

Qianyun Mei, Junhua Huang, Wanping Chen, Jie Tang, Chen Xu, Qi Yu, Ying Cheng, Lixin Ma, Xilan Yu, Shanshan Li

Oncotarget

DOI

2017

Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites

Qi Yu, Chong Tong, Mingdan Luo, Xiangyan Xue, Qianyun Mei, Lixin Ma, Xiaolan Yu, Xiaolan Yu, Wuxiang Mao, Lingbao Kong, Xilan Yu, Xilan Yu, Shanshan Li

PLoS ONE

DOI

2016

Anti-tumor activity of metformin: from metabolic and epigenetic perspectives

Xilan Yu, Xilan Yu, Wuxiang Mao, Yansheng Zhai, Chong Tong, Min Liu, Lixin Ma, Xiaolan Yu, Xiaolan Yu, Shanshan Li

Oncotarget

DOI

2016

Non-metabolic functions of glycolytic enzymes in tumorigenesis

Xilan Yu, Shanshan Li

Oncogene

DOI

李珊珊

精选作品

期刊论文

Author Correction: The SESAME complex regulates cell senescence through the generation of acetyl-CoA

Local acetyl-CoA metabolism and acetate recycling as epigenetic regulators of chromatin dynamics

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1

Author Correction: Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy

Specific regulation of epigenome landscape by metabolic enzymes and metabolites

Cla4 phosphorylates histone methyltransferase Set1 to prevent its degradation by the APC/C Cdh1 complex

Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability

Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence

The TORC1 activates Rpd3L complex to deacetylate Ino80 and H2A.Z and repress autophagy

Transcriptional regulation of autophagy by chromatin remodeling complex and histone variant

SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing

Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy

Acetylation-dependent SAGA complex dimerization promotes nucleosome acetylation and gene transcription

妊娠期运动降低SHR子代血压的钙通道CACNA1C基因DNA甲基化机制

The SESAME complex regulates cell senescence through the generation of acetyl-CoA

Interplay Between Glucose Metabolism and Chromatin Modifications in Cancer

Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation

Histone acetyltransferase Gcn5 regulates gene expression by promoting the transcription of histone methyltransferase SET1

Exogenous pyruvate represses histone gene expression and inhibits cancer cell proliferation via the NAMPT–NAD+–SIRT1 pathway

Set1-catalyzed H3K4 trimethylation antagonizes the HIR/Asf1/Rtt106 repressor complex to promote histone gene expression and chronological life span

Glycolysis regulates gene expression by promoting the crosstalk between H3K4 trimethylation and H3K14 acetylation in Saccharomyces cerevisiae

运动改善高血压肠系膜动脉LTCC和BKCa通道功能的表观遗传调控机制

Reciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in Cancer

Regulation of DNA replication-coupled histone gene expression

Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites

Anti-tumor activity of metformin: from metabolic and epigenetic perspectives

Non-metabolic functions of glycolytic enzymes in tumorigenesis

研究方向