百晓学者学者目录

梁曦

助理教授、博士生导师、硕士生导师,青岛大学

精选作品

期刊论文

2026

ILA-producing bifidobacterium bifidum ameliorates chronic kidney disease via AHR signaling by modulating the gut-kidney axis.

Qinglian Hua, Yang Meng, Jin-Peng Hu, Yanchen Wei, H. Yi, Xi Liang, Lan-Wei Zhang, Zhe Zhang

Food Research International

2026

Bile salt hydrolase-active bifidobacterium animalis improves sarcopenia via the gut microbiota-bile acid-FXR-FGF15 axis and its functional fermented milk preparation.

Qinglian Hua, Qiyu Ma, H. Yi, Lan-Wei Zhang, Xi Liang, Zhe Zhang

Food Chemistry

2026

Compound Yeast Culture Reshapes Gut Microbiota and Functional Pathways to Enhance Antioxidant Capacity and Immune Homeostasis in Suckling Calves

Xue-Qiang Li, Xi Liang, Puguo Hao, Jingze Wu, Da-Cheng Liu

Microorganisms

2026

Early-Life Diarrhea Disrupts Antioxidant–Immune Homeostasis and Gut Microbiota in Suckling Calves

Xi Liang, Xue-Qiang Li, Ningning Mi, Yingga Wu, Jingze Wu, Hui Chen, Da-Cheng Liu

Biology

2026

FXR‐Mediated Atherosclerosis Alleviation by B. animalis F1‐7 Through Bile Acid Metabolism‐Driven Gut–Liver Axis Modulation

Tianhu Shan, Jiawen Wang, Yanyang Liu, Huaqi Zhang, Zhe Zhang, Lanwei Zhang, Hui Liang, Xi Liang

Food Frontiers

2025

Yeast culture improves growth, antioxidant status, immunity, and gut microbiota homeostasis in preweaning Holstein calves

Xue-Qiang Li, Xiaolin Yang, Shixiong Liu, Xi Liang, Hui Chen, Da-Cheng Liu

Frontiers in Veterinary Science

2025

Yeast culture in weaned lamb feed: a proteomic journey into enhanced rumen health and growth

Xue-Qiang Li, Xiaolin Yang, Hui Chen, Shixiong Liu, Puguo Hao, Jie Ning, Yingga Wu, Xi Liang, Yufei Zhang, Da-Cheng Liu

Journal of Animal Science and Biotechnology

2024

Bifidobacterium improves oestrogen-deficiency-induced osteoporosis in mice by modulating intestinal immunity.

Jin-Can Zhang, Xi Liang, Xiaoying Tian, Maozhen Zhao, Yunjuan Mu, H. Yi, Zhe Zhang, Lan-Wei Zhang

Food & Function

2024

Study on the Mechanism of Bifidobacterium animalis subsp. lactis F1-3–2 Regulating Bile Acid Metabolism Through TMA-TMAO Pathway to Improve Atherosclerosis

Xiumei Zheng, Zhe Zhang, Tianhu Shan, Maozhen Zhao, Haiyan Lu, Lan-Wei Zhang, Xi Liang

Probiotics and Antimicrobial Proteins

2024

Bifidobacterium animalis subsp. lactis F1-7 Alleviates Lipid Accumulation in Atherosclerotic Mice via Modulating Bile Acid Metabolites to Downregulate Intestinal FXR.

Xi Liang, Xiumei Zheng, Peng Wang, Hua-Qi Zhang, Yiqing Ma, Huichang Liang, Zhe Zhang

Journal of Agricultural and Food Chemistry

2024

Probiotics induce intestinal IgA secretion in weanling mice potentially through promoting intestinal APRIL expression and modulating the gut microbiota composition.

Maozhen Zhao, Xi Liang, Yang Meng, Haiyan Lu, Kai Lin, P. Gong, Tong-Jie Liu, H. Yi, Jian-Cun Pan, Yongjiu Zhang, Zhe Zhang, Lan-Wei Zhang

Food & Function

2024

Study on the Regulatory Mechanism of Niacin Combined with B. animalis F1-7 in Alleviating Alcoholic Fatty Liver Disease by Up-Regulating GPR109A

Xi Liang, Tianhu Shan, Xiumei Zheng, Zhe Zhang, Yanping Fan, Huaqi Zhang, Lanwei Zhang, Hui Liang

Nutrients

2023

Probiotics alleviate food protein allergy in mice by activating TLR4 signaling pathway.

Xiaoying Tian, Xi Liang, Hong He, Qing-Yu Cui, Qiqi Liu, Rong-Bo Fan, Tong-Jie Liu, H. Yi, P. Gong, Qingzhu Wang, Lan-Wei Zhang

Molecular Nutrition & Food Research

2023

Metabolite acetyl-L-carnitine participates in Bif. Animalis F1-7 to ameliorate atherosclerotic inflammation by downregulating theTLR4/NFκB pathway

Xi Liang, Zhe Zhang, Xiaoying Tian, Qing-Yu Cui, Haiyan Lu, Maozhen Zhao, Tong-Jie Liu, H. Yi, P. Gong, Lan-Wei Zhang

Food Science and Human Wellness

2023

Bifidobacterium bifidum Ameliorates DSS-Induced Colitis in Mice by Regulating AHR/NRF2/NLRP3 Inflammasome Pathways through Indole-3-lactic Acid Production.

Qing-Yu Cui, Zhe Zhang, Xiaoying Tian, Xi Liang, Youyou Lu, Yi-Xin Shi, Malina Kuerman, Rui Wang, Yu Zhou, P. Gong, Kai Lin, H. Yi, Jiadong Li, Tong-Jie Liu, Lan-Wei Zhang

Journal of Agricultural and Food Chemistry

2022

Bifidobacterium bifidum relieved DSS-induced colitis in mice potentially by activating the aryl hydrocarbon receptor.

Qing-Yu Cui, Xiaoying Tian, Xi Liang, Zhe Zhang, Rui Wang, Yu Zhou, H. Yi, P. Gong, Kai Lin, Tong-Jie Liu, Lan-Wei Zhang

Food & Function

2022

Bifidobacterium animalis sup F1-7 Acts as an Effective Activator to Regulate Immune Response Via Casepase-3 and Bak of FAS/CD95 Pathway

Youyou Lu, Xi Liang, Yeting Wu, Ruiqi Wang, Tong-Jie Liu, H. Yi, Zhuang Yu, Zhe Zhang, P. Gong, Lan-Wei Zhang

Probiotics and Antimicrobial Proteins

2022

Bifidobacterium animalis KV9 and Lactobacillus vaginalis FN3 alleviated β-lactoglobulin-induced allergy by modulating dendritic cells in mice

Xiaoying Tian, Rong-Bo Fan, Hong He, Qing-Yu Cui, Xi Liang, Qiqi Liu, Tong-Jie Liu, Kai Lin, Zhe Zhang, H. Yi, P. Gong, Lan-Wei Zhang

Frontiers in Immunology

2021

植物乳杆菌F3-2联合甘露低聚糖通过上调短链脂肪酸水平抑制PPARγ改善小鼠肥胖

赵茂臻,梁曦,张喆,吕优优,王引,刘同杰,易华西,公丕民,张兰威

《食品与发酵工业》

2021

Krill Oil Combined with Bifidobacterium animalis subsp. lactis F1-7 Alleviates the Atherosclerosis of ApoE−/− Mice

Xi Liang, Zhe Zhang, Youyou Lv, Haiyan Lu, Tong-Jie Liu, H. Yi, Maozhen Zhao, Lan-Wei Zhang, P. Gong

Foods

2021

Lactobacillus rhamnosus GG Derived Extracellular Vesicles Modulate Gut Microbiota and Attenuate Inflammatory in DSS-Induced Colitis Mice

Ling-Jun Tong, Xinyi Zhang, Haining Hao, Qiqi Liu, Zihan Zhou, Xi Liang, Tong-Jie Liu, P. Gong, Lan-Wei Zhang, Zheng-Yuan Zhai, Yan-Ling Hao, H. Yi

Nutrients

2021

Effect of Extracellular Vesicles Derived From Lactobacillus plantarum Q7 on Gut Microbiota and Ulcerative Colitis in Mice

Haining Hao, Xinyi Zhang, Ling-Jun Tong, Qiqi Liu, Xi Liang, Yu-Shan Bu, P. Gong, Tong-Jie Liu, Lan-Wei Zhang, Yong-Jun Xia, L. Ai, H. Yi

Frontiers in Immunology

2021

The edible Lactobacillus paracasei X11 with Konjac glucomannan promotes intestinal motility in zebrafish

Youyou Lu, Junxue Zhang, Xiaohong Zhou, Meiyu Guan, Zhe Zhang, Xi Liang, Ling-Jun Tong, H. Yi, P. Gong, Lu Bai, Hui Zhou, Tong-Jie Liu, Lan-Wei Zhang

Neurogastroenterology and Motility

2021

Bifidobacterium animalis F1-7 in combination with konjac glucomannan improves constipation in mice via humoral transport.

Youyou Lu, Zhuang Yu, Zhe Zhang, Xi Liang, P. Gong, H. Yi, Liuqing Yang, Tong-Jie Liu, Han-Ping Shi, Lan-Wei Zhang

Food & Function

2021

Mechanisms underlying the promotion of 5‐hydroxytryptamine secretion in enterochromaffin cells of constipation mice by Bifidobacterium and Lactobacillus

Youyou Lu, Zhe Zhang, Ling-Jun Tong, Xiaohong Zhou, Xi Liang, H. Yi, P. Gong, Tong-Jie Liu, Lan-Wei Zhang, Liuqing Yang, Han-Ping Shi

Neurogastroenterology and Motility

2021

Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota

Ling-Jun Tong, Haining Hao, Zhe Zhang, Youyou Lv, Xi Liang, Qiqi Liu, Tong-Jie Liu, P. Gong, Lan-Wei Zhang, Fang-Fang Cao, G. Pastorin, Chuen N. Lee, Xiaoyuan Chen, Jiong-Wei Wang, H. Yi

Theranostics

2021

Potential probiotics Lactobacillus casei K11 combined with plant extracts reduce markers of type 2 diabetes mellitus in mice

Zhe Zhang, Lu Bai, Meiyu Guan, Xiaohong Zhou, Xi Liang, Youyou Lv, H. Yi, Hui Zhou, Tong-Jie Liu, P. Gong, Ji-Ze Sun, Lan-Wei Zhang

Journal of Applied Microbiology

2021

The Metabolite β-Hydroxybutyrate of Lactobacillus Plantarum YZX21 Improves Type 2 Diabetes By Promoting Intestinal Secretion of GLP-1

Zhe Zhang, Xi Liang, Ling-Jun Tong, Youyou Lv, Haiyan Lu, Maozhen Zhao, P. Gong, Tong-Jie Liu, H. Yi, Lan-Wei Zhang

2020

Lactobacillus casei YRL577 ameliorates markers of non-alcoholic fatty liver and alters expression of genes within the intestinal bile acid pathway

Zhe Zhang, Hui Zhou, Xiaohong Zhou, Ji-Ze Sun, Xi Liang, Youyou Lv, Lu Bai, Junxue Zhang, P. Gong, Tong-Jie Liu, H. Yi, Jing-Feng Wang, Lan-Wei Zhang

British Journal of Nutrition

2020

Lactobacillus casei YRL577 combined with plant extracts reduce markers of non-alcoholic fatty liver disease in mice

Zhe Zhang, Hui Zhou, Meiyu Guan, Xiaohong Zhou, Xi Liang, Youyou Lv, Lu Bai, Junxue Zhang, P. Gong, Tong-Jie Liu, H. Yi, Jing-Feng Wang, Lan-Wei Zhang

British Journal of Nutrition

2020

Konjac glucomannan with probiotics acts as a combination laxative to improverelieve constipation in mice by increasing short-chain fatty acid metabolism and 5-hydroxytryptamine hormone release.

Youyou Lu, Junxue Zhang, Zhe Zhang, Xi Liang, Tong-Jie Liu, H. Yi, P. Gong, Lingli Wang, Wen-Jun Yang, Xinyi Zhang, Lan-Wei Zhang, Liuqing Yang, Han-Ping Shi

Nutrition (Burbank, Los Angeles County, Calif.)

2020

Evaluation of probiotics for improving and regulation metabolism relevant to type 2 diabetes in vitro

Zhe Zhang, Xi Liang, Youyou Lv, H. Yi, Yu-Jie Chen, Lu Bai, Hui Zhou, Tong-Jie Liu, Rui Li, Lan-Wei Zhang

2020

Reduction of intestinal trimethylamine by probiotics ameliorated lipid metabolic disorders associated with atherosclerosis.

Xi Liang, Zhe Zhang, Youyou Lv, Li-Tao Tong, Tong-Jie Liu, H. Yi, Xiaohong Zhou, Zhuang Yu, Xiaoying Tian, Qing-Yu Cui, Jie-Bing Yang, P. Gong, Lan-Wei Zhang

Nutrition (Burbank, Los Angeles County, Calif.)

2020

Study on intestinal survival and cholesterol metabolism of probiotics

Xi Liang, Youyou Lv, Zhe Zhang, H. Yi, Tong-Jie Liu, Rui Li, Zhuang Yu, Lan-Wei Zhang

2020

Probiotics improved hyperlipidemia in mice induced by a high cholesterol diet via downregulating FXR.

Xi Liang, Zhe Zhang, Xiaohong Zhou, Youyou Lu, Rui Li, Zhuang Yu, Ling-Jun Tong, P. Gong, H. Yi, Tong-Jie Liu, Lan-Wei Zhang

Food & Function

2019

Study of gastrointestinal tract viability and motility via modulation of serotonin in a zebrafish model by probiotics.

Youyou Lu, Zhe Zhang, Xi Liang, Yu-Jie Chen, Junxue Zhang, H. Yi, Tong-Jie Liu, Liuqing Yang, Han-Ping Shi, Lan-Wei Zhang

Food & Function

会议论文

2024

烟酸联合动物双歧杆菌乳亚种F1-7调节GPR109A改善酒精性脂肪肝的作用机制研究

梁曦,张喆,张华琦,梁惠,易华西,张兰威

《中国食品科学技术学会第二十一届年会论文摘要集》

2022

Bif. Animalis F1-7参与胆汁酸代谢靶向调节FXR改善动脉粥样硬化

梁曦,卢海燕,公丕民,刘同杰,易华西,张兰威

《中国食品科学技术学会第十八届年会摘要集》

2022

Bif.Animalis F1-7通过作用差异代谢物ALC调控TLR4/NFκB通路缓解动脉粥样硬化相关炎性反应

梁曦,张喆,张华琦,王鹏,孙礼瑞,张兰威,梁惠

《第七届海峡两岸暨港澳营养科学大会摘要集》

2021

益生菌靶向调控5-HT分泌缓解阿片诱导型肿瘤便秘的效果与新机制

吕优优,梁曦,张喆,易华西,张兰威

《第十六届益生菌与健康国际研讨会摘要集》

2020

双歧杆菌F1-7联合魔芋葡甘露聚糖通过体液转通路协同改善小鼠便秘效果与机制

吕优优,张喆,梁曦,易华西,张兰威

《中国食品科学技术学会第十七届年会》

2020

益生菌调控L细胞GLP-1分泌及作用机制研究

张喆,梁曦,仝令君,吕优优,易华西,张兰威

《第十五届益生菌与健康国际研讨会摘要集》

2020

益生菌与益生元通过调节肠嗜铬细胞释放五羟色胺及体液转运对便秘的改善作用及相关机制

吕优优,梁曦,张喆,仝令君,易华西,张兰威

《第十五届益生菌与健康国际研讨会摘要集》

2020

益生菌参与TMA-TMAO-脂质代谢改善动脉粥样硬化作用机制

梁曦,张喆,吕优优,公丕民,张兰威

《第十五届益生菌与健康国际研讨会摘要集》

2020

全谱代谢组学揭示益生菌调控2型糖尿病新机制

张喆,梁曦,仝令君,吕优优,易华西,张兰威

《中国食品科学技术学会第十七届年会摘要集》

2020

益生菌通过下调FXR缓解高胆固醇诱导的高脂血症

梁曦,张喆,吕优优,仝令君,公丕民,易华西,刘同杰,张兰威

《中国食品科学技术学会第十七届年会摘要集》

2019

基于体外实验筛选具有改善胰岛素抵抗和调节肠道激素释放功能的益生菌及其相关机制

张喆,梁曦,吕优优,易华西,刘同杰,张兰威

《中国食品科学技术学会第十六届年会暨第十届中美食品业高层论坛论文摘要集》

2019

动物双歧乳杆菌F1-7通过调节五羟色胺分泌促进斑马鱼肠蠕动

吕优优,张喆,梁曦,陈玉洁,张峻雪,易华西,刘同杰,杨柳青,石汉平,张兰威

《中国食品科学技术学会第十六届年会暨第十届中美食品业高层论坛论文摘要集》

2019

促进胆固醇代谢益生菌特性及其降脂途径的细胞学研究

梁曦,张喆,吕优优,易华西,刘同杰,张兰威

《中国食品科学技术学会第十六届年会暨第十届中美食品业高层论坛论文摘要集》

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