林泓域｜厦门大学｜学者主页

2026

Manganese-Doped Fluorinated Zeolitic Imidazolate Framework-90 for Activatable 1H/19F MRI and Metalloimmunotherapy of Hepatocellular Carcinoma

Yuanxi Zheng, Lingxuan Li, Weijia Fu, Yifan Li, Jingxue Yan, Xiaoqin Chi, 尹震宇, Hongyu Lin, Jinhao Gao

ACS Applied Materials & Interfaces

DOI

2026

Fluorinated Core–Shell Metal–Organic Framework-Based Dual-Activated 19F MRI Nanoprobes for In Vivo Visualization of the Tumor Microenvironment

Yifan Fan, Yuanxi Zheng, Xiaoqin Chi, Junjie Wang, YB Jiang, Chaoyong James Yang, Hongyu Lin, Jinhao Gao

Analytical Chemistry

DOI

2026

3,5-Bis(2-hexafluoro-isopropoxyl)phenyl: A Super-Fluorinated Moiety with Favorable Water-Solubility and Modifiability for 19F Magnetic Resonance Imaging

YB Jiang, Jiahao Yang, Lexue Lin, Nan Xiong, Hongyu Lin, Jinhao Gao

Journal of the American Chemical Society

DOI

2026

Nuclear Spin Relaxation Modulation of Fluorinated Deep Eutectic Solvents for Radiofrequency Information Encoding and Display

YB Jiang, Junjie Wang, Chenlei Tan, Lexue Lin, Yifan Li, Hongyu Lin, Jinhao Gao

Advanced Materials

DOI

2026

Hollow Prussian blue nanoparticles encapsulating fluorinated ionic liquids for activatable 19F magnetic resonance imaging and redox regulation of liver inflammation

Limin Chen, Yuanxi Zheng, Juan Shao, YB Jiang, Li Zheng, Lingxuan Li, Xiaoqin Chi, Hongyu Lin, Bengang Xing, Jinhao Gao

Nano Today

DOI

2026

SABRE Hyperpolarized Multichannel 19 F NMR for Sensitive Detection of Multiple Disease Marker Enzymes on a Benchtop NMR

Li Zheng, Qiwei Peng, Huijun Sun, Jingwei Deng, Yuhang Jiang, Yubin Xiong, Limin Chen, Xiaohong Cui, Hongyu Lin, Zhong Chen, Xinchang Wang, Jinhao Gao

Angewandte Chemie

DOI

2026

Bioactive manganese oxide nanoassembly as a highly sensitive magnetic resonance imaging probe for grading diagnosis of liver injury

Na Young Yang, Chunli Wang, Jiaxi Wang, Jikai Xia, Qingyong Cao, Henan Cao, Yingying Wang, Chunmin Bo, Shukai Ge, Chengjie Sun, Zhongyuan Cai, Hongyu Lin, Kun Liu

Journal of Nanobiotechnology

DOI

2025

Cu-ZIF-8金属有机框架纳米材料的合成及抗菌性能

李京燕，熊楠，樊一凡，林泓域，高锦豪

《厦门大学学报(自然科学版)》

2025

A Multifunctional Metal-Organic Frameworks-Based Nanoplatform for Tumor Imaging and Antimetastasis Immunotherapy by Exploiting the Versatility of Manganese Ions

Yuanxi Zheng, Yifan Fan, Yifan Li, Lingxuan Li, Xiaoqin Chi, Hongyu Lin, Jinhao Gao

ACS Applied Materials & Interfaces

DOI

2025

Cinnamaldehyde-Containing Organoarsenic Prodrug with Synergistic Anticancer Activity via Redox Dyshomeostasis

Hui Xiong, Jingxue Yan, Jun Zhang, Yuhang Jiang, Xiaoqin Chi, Hongyu Lin, Jinhao Gao

Molecular Pharmaceutics

DOI

2025

Small Fluorinated Aromatic Molecule‐Based Radiofrequency Identification Tags Enabled by Stepwise Tuning of Nuclear Shielding

Yuhang Jiang, Limin Chen, Junjie Wang, Hongyu Lin, Jinhao Gao

Angewandte Chemie

DOI

2025

Super-multiplexed imaging and coding in the range of radio frequency

Yuhang Jiang, Yifan Fan, Limin Chen, Hongyu Lin, Jinhao Gao

Nature Communications

DOI

2025

Sensitive Multichannel 19F Magnetic Resonance Imaging Enabled by Paramagnetic Fluorinated Ionic Liquid-Based Probes

Limin Chen, Yuhang Jiang, Nan Xiong, Yifan Fan, Hongyu Lin, Jinhao Gao

ACS Nano

DOI

2025

Subnanometer ultra-thin magnetic nanosheets for highly sensitive magnetic resonance angiography

Kun Liu, Na Young Yang, Chunmin Bo, Xianglong Zhu, Yifan Fan, Hong Hao, Zhen Jin, Jinhao Gao, Hongyu Lin, Chunli Wang

Chemical Engineering Journal

DOI

2025

Visualizing enterohepatic circulation in vivo by sensitive 19F MRI with a fluorinated ferrous chelate-based small molecule probe

Lingxuan Li, Ao Li, Junjie Wang, Juan Shao, Huijie Zhou, Zixiong Peng, Hongyu Lin, Jinhao Gao

Biomaterials

DOI

2024

Fluorinated 1,7-DO2A-Based Iron(II) Complexes as Sensitive 19F MRI Molecular Probes for Visualizing Renal Dysfunction in Living Mice

Lingxuan Li, Chuankai Chen, Yifan Bu, Junjie Wang, Juan Shao, Ao Li, Hongyu Lin, Jinhao Gao

Analytical Chemistry

DOI

2023

Fluorinated Iron Metal–Organic Frameworks for Activatable 19F Magnetic Resonance Imaging and Synergistic Therapy of Tumors

Yifan Fan, Dongxia Chen, Limin Chen, Kun Liu, Yuanxi Zheng, Lingxuan Li, Jingyan Li, Hongyu Lin, Jinhao Gao

Nano Letters

DOI

2023

Glycan Metabolic Fluorine Labeling for In Vivo Visualization of Tumor Cells and In Situ Assessment of Glycosylation Variations

Dongxia Chen, Yaying Lin, Yifan Fan, Lingxuan Li, Chenlei Tan, Junjie Wang, Hongyu Lin, Jinhao Gao

Angewandte Chemie

DOI

2023

Macrophage Reprogramming via Targeted ROS Scavenging and COX-2 Downregulation for Alleviating Inflammation

Xiangjie Luo, Hui Xiong, Yuhang Jiang, Yifan Fan, Cuicui Zuo, Dongxia Chen, Limin Chen, Hongyu Lin, Jinhao Gao

Bioconjugate Chemistry

DOI

2023

Nanoparticle-Based Activatable MRI Probes for Disease Imaging and Monitoring

Yifan Fan, Limin Chen, Yuanxi Zheng, Ao Li, Hongyu Lin, Jinhao Gao

Chemical & Biomedical Imaging

DOI

2023

Water-Soluble Chemically Precise Fluorinated Molecular Clusters for Interference-Free Multiplex 19F MRI in Living Mice

Xiaoxue Tang, Ao Li, Cuicui Zuo, Xing Liu, Xiangjie Luo, Limin Chen, Lingxuan Li, Hongyu Lin, Jinhao Gao

ACS Nano

DOI

2023

Metabolic fluorine labeling and hotspot imaging of dynamic gut microbiota in mice

Dongxia Chen, Junnan Guo, Ao Li, Chengjie Sun, Huibin Lin, Huibin Lin, Hongyu Lin, Hongyu Lin, Chaoyong James Yang, Wei Wang, Jinhao Gao

Science Advances

DOI

2023

Small Molecule Probes for 19 F Magnetic Resonance Imaging

Ao Li, Xiangjie Luo, Dongxia Chen, Lingxuan Li, Hongyu Lin, Jinhao Gao

Analytical Chemistry

DOI

2023

Constructing sequence-controlled heterolayered dendritic lanthanide chelates via a one-pot strategy using orthogonal chemistry

Zhaoxuan Yang, Haojin Lin, Haojin Lin, Yaying Lin, Jinzhi Wang, Yifan Bu, Hongyu Lin, Hongyu Lin, Jinhao Gao

Chemical Communications

DOI

2022

基于硼酸酯的19F磁共振分子探针的设计合成及活体深组织活性氧物种的激活响应成像（英文）

李奥，李凌轩，左翠翠，陈传凯，樊一凡，步逸凡，林泓域，高锦豪

《高等学校化学学报》

2022

Bio-orthogonal Metabolic Fluorine Labeling Enables Deep-Tissue Visualization of Tumor Cells In Vivo by 19 F Magnetic Resonance Imaging

Dongxia Chen, Yaying Lin, Ao Li, Xiangjie Luo, Chaoyong James Yang, Jinhao Gao, Hongyu Lin

Analytical Chemistry

DOI

2022

Berplatin: A Conjugate of Berberine and Cisplatin Serving as a Potent Antitumor Agent with Distinctive Tumor Cell Uptake and Minimal Side Effects

Beibei Xu, Xiangjie Luo, Jing Xiong, Qianwen Shen, Yongcheng Su, Ziyu Lei, Jiangquan Li, Hongyu Lin, Wenqing Zhang, Xiaoting Hong, Fu-Xing Zhang, Yan-yan Zhan, Jinhao Gao, Tianhui Hu

Advanced Therapeutics

DOI

2022

Multicolor 19F magnetic resonance imaging: A promising medical technique for in vivo visualization of multiple biological targets

Yuhang Jiang, Xiangjie Luo, Limin Chen, Hongyu Lin, Jinhao Gao

Fundamental Research

DOI

2022

Z-REX uncovers a bifurcation in function of Keap1 paralogs

Alexandra Van Hall‐Beauvais, Jesse R. Poganik, Kuan‐Ting Huang, Saba Parvez, Yi Zhao, Hongyu Lin, Xuyu Liu, Marcus J. C. Long, Yimon Aye

eLife

DOI

2022

Author response: Z-REX uncovers a bifurcation in function of Keap1 paralogs

Alexandra Van Hall‐Beauvais, Jesse R. Poganik, Kuan‐Ting Huang, Saba Parvez, Yi Zhao, Hongyu Lin, Xuyu Liu, Marcus J. C. Long, Yimon Aye

DOI

2022

19F Barcoding Enables Multiplex Detection of Biomarkers Associated with Organ Injury and Cancer

Xiangjie Luo, Bilun Kang, Xiaoqin Chi, Hui Xiong, Dongxia Chen, Yifan Fan, Lingxuan Li, Limin Chen, Ao Li, Jinhao Gao, Hongyu Lin

Angewandte Chemie

DOI

2022

An Activatable 19F MRI Molecular Probe for Sensing and Imaging of Norepinephrine

Lingxuan Li, Ao Li, Yaying Lin, Dongxia Chen, Bilun Kang, Hongyu Lin, Jinhao Gao

ChemistryOpen

DOI

2022

Multinuclear Mn(II) united-DOTA complexes with enhanced inertness and high MRI contrast ability

Chengjie Sun, Zhaoxuan Yang, Peng Wu, Xiangjie Luo, Kun Liu, Binju Wang, Hongyu Lin, Jinhao Gao

Cell Reports Physical Science

DOI

2022

Photoinduced Superhydrophilicity of Gd-Doped TiO2 Ellipsoidal Nanoparticles Boosts T1 Contrast Enhancement for Magnetic Resonance Imaging

Kun Liu, Zhongyuan Cai, Xiaoqin Chi, Bilun Kang, Shengxiang Fu, Xiangjie Luo, Zhiwei Lin, Hua Ai, Jinhao Gao, Hongyu Lin

Nano Letters

DOI

2022

Tandem Chemoimmunotherapy by a Cascade-Responsive Molecular Prodrug

Zhaoxuan Yang, Xiangjie Luo, Yaying Lin, Jiaqi Huang, Hongyu Lin, Jinhao Gao

ACS Chemical Biology

DOI

2022

Zwitterion-Coated Ultrasmall MnO Nanoparticles Enable Highly Sensitive T1-Weighted Contrast-Enhanced Brain Imaging

Ruixue Wei, Kun Liu, Ke Zhang, Yifan Fan, Hongyu Lin, Jinhao Gao

ACS Applied Materials & Interfaces

DOI

2022

A dual-responsive doxorubicin–indoximod conjugate for programmed chemoimmunotherapy

Zhaoxuan Yang, Jiaqi Huang, Yaying Lin, Xiangjie Luo, Haojin Lin, Haojin Lin, Hongyu Lin, Hongyu Lin, Jinhao Gao

RSC Chemical Biology

DOI

2021

Activatable Multiplexed 19F Magnetic Resonance Imaging Visualizes Reactive Oxygen and Nitrogen Species in Drug-Induced Acute Kidney Injury

Ao Li, Xiangjie Luo, Lingxuan Li, Dongxia Chen, Xing Liu, Zhaoxuan Yang, Lijiao Yang, Jinhao Gao, Hongyu Lin

Analytical Chemistry

DOI

2021

Arsenite-loaded albumin nanoparticles for targeted synergistic chemo-photothermal therapy of HCC

Ke Zhang, Dan Li, Bin Zhou, Jiani Liu, Xiangjie Luo, Ruixue Wei, Lizhu Wang, Xiaojun Hu, Zhongzhen Su, Hongyu Lin, Jinhao Gao, Hong Shan

Biomaterials Science

DOI

2021

Redox-Activated Contrast-Enhanced T 1‑Weighted Imaging Visualizes Glutathione-Mediated Biotransformation Dynamics in the Liver

Kun Liu, Bilun Kang, Xiangjie Luo, Zhaoxuan Yang, Chengjie Sun, Ao Li, Yifan Fan, Xiaoyuan Shawn Chen, Jinhao Gao, Hongyu Lin

ACS Nano

DOI

2021

Hypoxia-Activated Prodrug Enabling Synchronous Chemotherapy and HIF-1α Downregulation for Tumor Treatment

Xiangjie Luo, Ao Li, Xiaoqin Chi, Yaying Lin, Xing Liu, Lifan Zhang, Xinhui Su, Zhenyu Yin, Hongyu Lin, Jinhao Gao

Bioconjugate Chemistry

DOI

2021

Activatable 19 F MRI Nanoprobes for Visualization of Biological Targets in Living Subjects

Hongyu Lin, Xiaoxue Tang, Ao Li, Jinhao Gao

Advanced Materials

DOI

2021

A camptothecin prodrug induces mitochondria-mediated apoptosis in cancer cells with cascade activations

Xiangjie Luo, Xiaoqin Chi, Yaying Lin, Zhaoxuan Yang, Hongyu Lin, Jinhao Gao

Chemical Communications

DOI

2021

Deep-tissue real-time imaging of drug-induced liver injury with peroxynitrite-responsive 19 F MRI nanoprobes

Ao Li, Lingxuan Li, Xing Liu, Dongxia Chen, Yifan Fan, Hongyu Lin, Jinhao Gao

Chemical Communications

DOI

2020

基于竞争配位的Ca2+特异性响应1H/19F磁共振成像分子探针

陈洪明，唐小雪，林雅滢，龚玄清，林泓域，高锦豪

《无机化学学报》

2020

Nuclear innate sensors for nucleic acids in immunity and inflammation

Hongyu Lin, Xue-Tao Cao

Immunological Reviews

DOI

2020

A Fluorinated Ionic Liquid-Based Activatable 19F MRI Platform Detects Biological Targets

Xianglong Zhu, Xiaoxue Tang, Hongyu Lin, Saige Shi, Hehe Xiong, Qiuju Zhou, Ao Li, Wang Qiaoyang, Xiaoyuan Shawn Chen, Jinhao Gao

Chem

DOI

2020

Imaging Beyond Seeing: Early Prognosis of Cancer Treatment

Changrong Shi, Zijian Zhou, Hongyu Lin, Jinhao Gao

Small Methods

DOI

2020

Fluorinated Gadolinium Chelate-Grafted Nanoconjugates for Contrast-Enhanced T1-Weighted 1H and pH-Activatable 19F Dual-Modal MRI

Xiaoxue Tang, Xuanqing Gong, Jiang Ming, Dongxia Chen, Hongyu Lin, Jinhao Gao

Analytical Chemistry

DOI

2020

Activatable Mitochondria‐Targeting Organoarsenic Prodrugs for Bioenergetic Cancer Therapy

Xiangjie Luo, Xuanqing Gong, Liyun Su, Hongyu Lin, Zhaoxuan Yang, Xiaomei Yan, Jinhao Gao

Angewandte Chemie

DOI

2020

Recent advances of nanomedicines for liver cancer therapy

Xiaoqin Chi, Kun Liu, Xiangjie Luo, Zhenyu Yin, Hongyu Lin, Jinhao Gao

Journal of Materials Chemistry B

DOI

2020

Reversible redox-responsive 1 H/ 19 F MRI molecular probes

Hongming Chen, Xiaoxue Tang, Xuanqing Gong, Dongxia Chen, Ao Li, Chengjie Sun, Hongyu Lin, Jinhao Gao

Chemical Communications

DOI

2019

The long noncoding RNA Lnczc3h7a promotes a TRIM25-mediated RIG-I antiviral innate immune response

Hongyu Lin, Ming-Hong Jiang, Lun Liu, Zongheng Yang, Zhong-fei Ma, Shuo Liu, Yuanwu Ma, Lian-Feng Zhang, Xue-Tao Cao

Nature Immunology

DOI

2019

Cascaded Multiresponsive Self-Assembled 19F MRI Nanoprobes with Redox-Triggered Activation and NIR-Induced Amplification

Xiaoxue Tang, Xuanqing Gong, Ao Li, Hongyu Lin, Chenyu Peng, Xianzhong Zhang, Xiaoyuan Shawn Chen, Jinhao Gao

Nano Letters

DOI

2019

DOTA-Branched Organic Frameworks as Giant and Potent Metal Chelators

Chengjie Sun, Hongyu Lin, Xuanqing Gong, Zhaoxuan Yang, Yan Mo, Xiaoyuan Shawn Chen, Jinhao Gao

Journal of the American Chemical Society

DOI

2019

Surface Engineering to Boost the Performance of Nanoparticle‐Based T 1 Contrast Agents

Hongyu Lin, Kun Liu, Jinhao Gao

European Journal of Inorganic Chemistry

DOI

2019

Versatile Octapod-Shaped Hollow Porous Manganese(II) Oxide Nanoplatform for Real-Time Visualization of Cargo Delivery

Ruixue Wei, Xuanqing Gong, Hongyu Lin, Ke Zhang, Ao Li, Kun Liu, Hong Shan, Xiaoyuan Shawn Chen, Jinhao Gao

Nano Letters

DOI

2019

Sensitive Contrast-Enhanced Magnetic Resonance Imaging of Orthotopic and Metastatic Hepatic Tumors by Ultralow Doses of Zinc Ferrite Octapods

Lijiao Yang, Chengjie Sun, Hongyu Lin, Xuanqing Gong, Tiantian Zhou, Wen‐Ting Deng, Zhong Chen, Jinhao Gao

Chemistry of Materials

DOI

2019

Targeted arsenite-loaded magnetic multifunctional nanoparticles for treatment of hepatocellular carcinoma

Xiaoqin Chi, Renyuan Zhang, Tian Zhao, Xuanqing Gong, Ruixue Wei, Zhenyu Yin, Hongyu Lin, Dan Li, Hong Shan, Jinhao Gao

Nanotechnology

DOI

2019

A gadolinium-complex-based theranostic prodrug for in vivo tumour-targeted magnetic resonance imaging and therapy

Zhaoxuan Yang, Hongyu Lin, Jiaqi Huang, Ao Li, Chengjie Sun, Jonathan Richmond, Jinhao Gao

Chemical Communications

DOI

2019

A fluorinated bihydrazide conjugate for activatable sensing and imaging of hypochlorous acid by 19 F NMR/MRI

Ao Li, Xiaoxue Tang, Xuanqing Gong, Hongming Chen, Hongyu Lin, Jinhao Gao

Chemical Communications

DOI

2019

An extracellular pH-driven targeted multifunctional manganese arsenite delivery system for tumor imaging and therapy

Ke Zhang, Hongyu Lin, Junjie Mao, Xiangjie Luo, Ruixue Wei, Zhongzhen Su, Bin Zhou, Dan Li, Jinhao Gao, Hong Shan

Biomaterials Science

DOI

2018

Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response.

Ming-Hong Jiang, Shikun Zhang, Zongheng Yang, Hongyu Lin, Jun Zhu, Lun Liu, Wen-Die Wang, Shuo Liu, Wei Liu, Yuanwu Ma, Lian-Feng Zhang, Xue-Tao Cao

Cell

DOI

2018

Facile synthesis of aquo-cisplatin arsenite multidrug nanocomposites for overcoming drug resistance and efficient combination therapy

Jingyu Xin, Ke Zhang, Jiaqi Huang, Xiangjie Luo, Xuanqing Gong, Zhaoxuan Yang, Hongyu Lin, Hong Shan, Jinhao Gao

Biomaterials Science

DOI

2018

Biodegradable and Renal-Clearable Hollow Porous Iron Oxide Nanoboxes for in Vivo Imaging

Ruixue Wei, Zhongyuan Cai, Bin W. Ren, Ao Li, Hongyu Lin, Ke Zhang, Hongming Chen, Hong Shan, Hua Ai, Jinhao Gao

Chemistry of Materials

DOI

2018

A Self‐Assembled Biocompatible Nanoplatform for Multimodal MR/Fluorescence Imaging Assisted Photothermal Therapy and Prognosis Analysis

Lirong Wang, Hongyu Lin, Xiaoqin Chi, Chengjie Sun, Jiaqi Huang, Xiaoxue Tang, Hongming Chen, Xiangjie Luo, Zhenyu Yin, Jinhao Gao

Small

DOI

2018

The Roles of Morphology on the Relaxation Rates of Magnetic Nanoparticles

Lijiao Yang, Zhenyu Wang, Lingceng Ma, Ao Li, Jingyu Xin, Ruixue Wei, Hongyu Lin, Ruifang Wang, Zhong Chen, Jinhao Gao

ACS Nano

DOI

2018

Gold nanoparticles impair autophagy flux through shape-dependent endocytosis and lysosomal dysfunction

Hualu Zhou, Xuanqing Gong, Hongyu Lin, Hongming Chen, Dengtong Huang, Dan Li, Hong Shan, Jinhao Gao

Journal of Materials Chemistry B

DOI

2018

Iron-oxide-based twin nanoplates with strong T 2 relaxation shortening for contrast-enhanced magnetic resonance imaging

Ruixue Wei, Tiantian Zhou, Chengjie Sun, Hongyu Lin, Lijiao Yang, Bin W. Ren, Zhong Chen, Jinhao Gao

Nanoscale

DOI

2017

生物环境智能响应磁共振造影剂研究进展

孙乘杰，林泓域，高锦豪

《中国科学:化学》

2017

Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity

Meng Xia, Juan Liu, Shu-Xun Liu, Kun Chen, Hongyu Lin, Ming-Hong Jiang, Xiao-Qing Xu, Yi-Quan Xue, W. Liu, Yan Gu, Xiang Zhang, Zhiqing Li, Lin Yi, You-Cun Qian, Chen Zhou, Ru Li, Xuan Zhang, Zhanguo Li, Xue-Tao Cao

Nature Communications

DOI

2017

Surface manganese substitution in magnetite nanocrystals enhances T 1 contrast ability by increasing electron spin relaxation

Zhenghuan Zhao, Chengjie Sun, Jianfeng Bao, Lijiao Yang, Ruixue Wei, Jingliang Cheng, Hongyu Lin, Jinhao Gao

Journal of Materials Chemistry B

DOI

2017

Arsenite-loaded nanoparticles inhibit the invasion and metastasis of a hepatocellular carcinoma: in vitro and in vivo study

Xiaoqin Chi, Zhenyu Yin, Jianbin Jin, Hui Li, Jian Zhou, Zhenghuan Zhao, Sheng Zhang, Wenxiu Zhao, Chengrong Xie, Jie Li, Min Feng, Hongyu Lin, Xiaomin Wang, Jinhao Gao

Nanotechnology

DOI

2017

Activatable T1 Relaxivity Recovery Nanoconjugates for Kinetic and Sensitive Analysis of Matrix Metalloprotease 2

Xianglong Zhu, Hongyu Lin, Lirong Wang, Xiaoxue Tang, Lingceng Ma, Zhong Chen, Jinhao Gao

ACS Applied Materials & Interfaces

DOI

2017

Composition Tunable Manganese Ferrite Nanoparticles for Optimized T2 Contrast Ability

Lijiao Yang, Lingceng Ma, Jingyu Xin, Ao Li, Chengjie Sun, Ruixue Wei, Bin W. Ren, Zhong Chen, Hongyu Lin, Jinhao Gao

Chemistry of Materials

DOI

2017

Albumin-based nanoparticles loaded with hydrophobic gadolinium chelates as T 1 –T 2 dual-mode contrast agents for accurate liver tumor imaging

Lirong Wang, Hongyu Lin, Lingceng Ma, Jianbin Jin, Taipeng Shen, Ruixue Wei, Xiaomin Wang, Hua Ai, Zhong Chen, Jinhao Gao

Nanoscale

DOI

2017

Geometrical confinement directed albumin-based nanoprobes as enhanced T 1 contrast agents for tumor imaging

Lirong Wang, Hongyu Lin, Lingceng Ma, Chengjie Sun, Jiaqi Huang, Ao Li, Tian Zhao, Zhong Chen, Jinhao Gao

Journal of Materials Chemistry B

DOI

精选作品

期刊论文

Manganese-Doped Fluorinated Zeolitic Imidazolate Framework-90 for Activatable 1H/19F MRI and Metalloimmunotherapy of Hepatocellular Carcinoma

Fluorinated Core–Shell Metal–Organic Framework-Based Dual-Activated 19F MRI Nanoprobes for In Vivo Visualization of the Tumor Microenvironment

3,5-Bis(2-hexafluoro-isopropoxyl)phenyl: A Super-Fluorinated Moiety with Favorable Water-Solubility and Modifiability for 19F Magnetic Resonance Imaging

Nuclear Spin Relaxation Modulation of Fluorinated Deep Eutectic Solvents for Radiofrequency Information Encoding and Display

Hollow Prussian blue nanoparticles encapsulating fluorinated ionic liquids for activatable 19F magnetic resonance imaging and redox regulation of liver inflammation

SABRE Hyperpolarized Multichannel 19 F NMR for Sensitive Detection of Multiple Disease Marker Enzymes on a Benchtop NMR

Bioactive manganese oxide nanoassembly as a highly sensitive magnetic resonance imaging probe for grading diagnosis of liver injury

Cu-ZIF-8金属有机框架纳米材料的合成及抗菌性能

A Multifunctional Metal-Organic Frameworks-Based Nanoplatform for Tumor Imaging and Antimetastasis Immunotherapy by Exploiting the Versatility of Manganese Ions

Cinnamaldehyde-Containing Organoarsenic Prodrug with Synergistic Anticancer Activity via Redox Dyshomeostasis

Small Fluorinated Aromatic Molecule‐Based Radiofrequency Identification Tags Enabled by Stepwise Tuning of Nuclear Shielding

Super-multiplexed imaging and coding in the range of radio frequency

Sensitive Multichannel 19F Magnetic Resonance Imaging Enabled by Paramagnetic Fluorinated Ionic Liquid-Based Probes

Subnanometer ultra-thin magnetic nanosheets for highly sensitive magnetic resonance angiography

Visualizing enterohepatic circulation in vivo by sensitive 19F MRI with a fluorinated ferrous chelate-based small molecule probe

Fluorinated 1,7-DO2A-Based Iron(II) Complexes as Sensitive 19F MRI Molecular Probes for Visualizing Renal Dysfunction in Living Mice

Fluorinated Iron Metal–Organic Frameworks for Activatable 19F Magnetic Resonance Imaging and Synergistic Therapy of Tumors

Glycan Metabolic Fluorine Labeling for In Vivo Visualization of Tumor Cells and In Situ Assessment of Glycosylation Variations

Macrophage Reprogramming via Targeted ROS Scavenging and COX-2 Downregulation for Alleviating Inflammation

Nanoparticle-Based Activatable MRI Probes for Disease Imaging and Monitoring

Water-Soluble Chemically Precise Fluorinated Molecular Clusters for Interference-Free Multiplex 19F MRI in Living Mice

Metabolic fluorine labeling and hotspot imaging of dynamic gut microbiota in mice

Small Molecule Probes for 19 F Magnetic Resonance Imaging

Constructing sequence-controlled heterolayered dendritic lanthanide chelates via a one-pot strategy using orthogonal chemistry

基于硼酸酯的19F磁共振分子探针的设计合成及活体深组织活性氧物种的激活响应成像（英文）

Bio-orthogonal Metabolic Fluorine Labeling Enables Deep-Tissue Visualization of Tumor Cells In Vivo by 19 F Magnetic Resonance Imaging

Berplatin: A Conjugate of Berberine and Cisplatin Serving as a Potent Antitumor Agent with Distinctive Tumor Cell Uptake and Minimal Side Effects

Multicolor 19F magnetic resonance imaging: A promising medical technique for in vivo visualization of multiple biological targets

Z-REX uncovers a bifurcation in function of Keap1 paralogs

Author response: Z-REX uncovers a bifurcation in function of Keap1 paralogs

19F Barcoding Enables Multiplex Detection of Biomarkers Associated with Organ Injury and Cancer

An Activatable 19F MRI Molecular Probe for Sensing and Imaging of Norepinephrine

Multinuclear Mn(II) united-DOTA complexes with enhanced inertness and high MRI contrast ability

Photoinduced Superhydrophilicity of Gd-Doped TiO2 Ellipsoidal Nanoparticles Boosts T1 Contrast Enhancement for Magnetic Resonance Imaging

Tandem Chemoimmunotherapy by a Cascade-Responsive Molecular Prodrug

Zwitterion-Coated Ultrasmall MnO Nanoparticles Enable Highly Sensitive T1-Weighted Contrast-Enhanced Brain Imaging

A dual-responsive doxorubicin–indoximod conjugate for programmed chemoimmunotherapy

Activatable Multiplexed 19F Magnetic Resonance Imaging Visualizes Reactive Oxygen and Nitrogen Species in Drug-Induced Acute Kidney Injury

Arsenite-loaded albumin nanoparticles for targeted synergistic chemo-photothermal therapy of HCC

Redox-Activated Contrast-Enhanced T 1‑Weighted Imaging Visualizes Glutathione-Mediated Biotransformation Dynamics in the Liver

Hypoxia-Activated Prodrug Enabling Synchronous Chemotherapy and HIF-1α Downregulation for Tumor Treatment

Activatable 19 F MRI Nanoprobes for Visualization of Biological Targets in Living Subjects

A camptothecin prodrug induces mitochondria-mediated apoptosis in cancer cells with cascade activations

Deep-tissue real-time imaging of drug-induced liver injury with peroxynitrite-responsive 19 F MRI nanoprobes

基于竞争配位的Ca2+特异性响应1H/19F磁共振成像分子探针

Nuclear innate sensors for nucleic acids in immunity and inflammation

A Fluorinated Ionic Liquid-Based Activatable 19F MRI Platform Detects Biological Targets

Imaging Beyond Seeing: Early Prognosis of Cancer Treatment

Fluorinated Gadolinium Chelate-Grafted Nanoconjugates for Contrast-Enhanced T1-Weighted 1H and pH-Activatable 19F Dual-Modal MRI

Activatable Mitochondria‐Targeting Organoarsenic Prodrugs for Bioenergetic Cancer Therapy

Recent advances of nanomedicines for liver cancer therapy

Reversible redox-responsive 1 H/ 19 F MRI molecular probes

The long noncoding RNA Lnczc3h7a promotes a TRIM25-mediated RIG-I antiviral innate immune response

Cascaded Multiresponsive Self-Assembled 19F MRI Nanoprobes with Redox-Triggered Activation and NIR-Induced Amplification

DOTA-Branched Organic Frameworks as Giant and Potent Metal Chelators

Surface Engineering to Boost the Performance of Nanoparticle‐Based T 1 Contrast Agents

Versatile Octapod-Shaped Hollow Porous Manganese(II) Oxide Nanoplatform for Real-Time Visualization of Cargo Delivery

Sensitive Contrast-Enhanced Magnetic Resonance Imaging of Orthotopic and Metastatic Hepatic Tumors by Ultralow Doses of Zinc Ferrite Octapods

Targeted arsenite-loaded magnetic multifunctional nanoparticles for treatment of hepatocellular carcinoma

A gadolinium-complex-based theranostic prodrug for in vivo tumour-targeted magnetic resonance imaging and therapy

A fluorinated bihydrazide conjugate for activatable sensing and imaging of hypochlorous acid by 19 F NMR/MRI

An extracellular pH-driven targeted multifunctional manganese arsenite delivery system for tumor imaging and therapy

Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response.

Facile synthesis of aquo-cisplatin arsenite multidrug nanocomposites for overcoming drug resistance and efficient combination therapy

Biodegradable and Renal-Clearable Hollow Porous Iron Oxide Nanoboxes for in Vivo Imaging

A Self‐Assembled Biocompatible Nanoplatform for Multimodal MR/Fluorescence Imaging Assisted Photothermal Therapy and Prognosis Analysis

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