陈铮凯｜浙江理工大学｜学者主页

2026

Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles via Palladium‐Catalyzed [4 + 1] Oxidative Annulation of Trifluoroacetimidohydrazides and Isocyanides

Yu Zhang, Zhenwei Yu, Min Xia, Zhengkai Chen

European Journal of Organic Chemistry

DOI

2026

Rh(III)-Catalyzed Multicomponent Cascade Reaction of 2-Arylimidazo[1,2- a ]pyridines with CF3-Imidoyl Sulfoxonium Ylides via Multiple C–H Activation

Jian Chen, Huan Zhou, Zhengkai Chen

Organic Letters

DOI

2026

Rapid Assembly of Trifluoromethyl‐Substituted Thiazolidine‐2‐Thiones via [3 + 2] Annulation of Dithiocarbamate Salts with CF 3 ‐Imidoyl Sulfoxonium Ylides Under Mild Conditions

Feng Han, Qihua Chen, X Zhang, Zhengkai Chen

Advanced Synthesis & Catalysis

DOI

2026

Metal‐Free Synthesis of 3‐Trifluoromethyl‐1,2,4‐triazoles via [4+1] Cyclization of Trifluoroacetimidohydrazides With BrCF 2 COOEt as a C1 Synthon

Y Zhang, Min Xia, Zhengkai Chen

ChemistrySelect

DOI

2026

Rhodium(III)-Catalyzed C–H Bond Activation and [3+3] Spirocyclization of Benzoxazines with CF 3 -Imidoyl Sulfoxonium Ylides toward Trifluoromethyl-Substituted Spiroheterocyclic Compounds

Qihua Chen, Zhenye Cui, Zhengkai Chen

The Journal of Organic Chemistry

DOI

2026

Condition-controlled Rh( iii )-catalyzed C–H activation and annulation of 1-aryl-5-aminopyrazoles with CF 3 -imidoyl sulfoxonium ylides for the divergent synthesis of trifluoromethyl-functionalized pyrazole-fused heterocycles

Jian Chen, Huan Zhou, Zhengkai Chen

Organic Chemistry Frontiers

DOI

2026

Heating-induced cascade annulation of CF 3 -imidoyl sulfoxonium ylides with thioamides for the synthesis of multi-substituted imidazolines via sulfur and acyl migration

Zhenwei Yu, Yu Zhang, Zhengkai Chen

Organic Chemistry Frontiers

DOI

2025

Catalyst‐Controlled Cascade Annulation of CF 3 ‐Imidoyl Sulfoxonium Ylides with Activated Nitriles for the Divergent Synthesis of Trifluoromethyl‐Substituted Pyrroles and Quinolines

Feng Han, Guangming Wei, Qihua Chen, Zhengkai Chen

Advanced Synthesis & Catalysis

DOI

2025

Synthesis of Trifluoromethyl‐Substituted Tetrazoles via KI/TBHP‐Mediated Oxidative Annulation of Trifluoroacetimidohydrazides and Nitromethane

Jian Chen, Zijian Wang, Zhengkai Chen

Asian Journal of Organic Chemistry

DOI

2025

Synthesis of 2-Trifluoromethylindolines via Rh(III)-Catalyzed Chelation-Assisted C–H Bond Activation and Annulation of Anilines with CF 3 -Imidoyl Sulfoxonium Ylides

Pinyi Li, Jian Chen, Zuguang Yang, Xi Wang, Zhengkai Chen

The Journal of Organic Chemistry

DOI

2025

Synthesis of Spiro 3,3′-Cyclopropyl Oxindoles via Cyclopropanation of 3-Alkenyl-oxindoles with CF3-Imidoyl Sulfoxonium Ylides

Chen Li, Yu Zhang, Zhengkai Chen

The Journal of Organic Chemistry

DOI

2025

Rh(III)‐Catalyzed C(sp 2 )–H and C(sp 2 )–C(sp 2 ) Bond Activation of Aryl Oximes with CF 3 ‐Imidoyl Sulfoxonium Ylides: Access to N ‐(2‐Cyanoaryl)‐3‐(Trifluoromethyl)isoquinolin‐1( 2H )‐Imines

Pinyi Li, Jian Chen, Zuguang Yang, Zhengkai Chen

Advanced Synthesis & Catalysis

DOI

2025

Rh( iii )-catalyzed annulation of oxadiazolones with CF 3 -imidoyl sulfoxonium ylides: access to trifluoromethyl-substituted fused-dihydroisoquinolines

Sihao Ling, Qihua Chen, Zhengkai Chen

Organic & Biomolecular Chemistry

DOI

2025

Synthesis of trifluoromethyl-functionalized benzo[ de ][1,8]naphthyridines via Rh( iii )-catalyzed two-fold C–H activation of benzamidine hydrochlorides and annulation with CF 3 -imidoyl sulfoxonium ylides

Qihua Chen, Feng Han, Zhengkai Chen

New Journal of Chemistry

DOI

2024

强化学术牵引，深化科教融合：创新化学本科人才培养的探索与实践

左彪，张旖芝，陈铮凯，田厚宽，王勇能，张伟，王伟祖，郑旭明，王新平

《大学化学》

2024

Rhodium(III)-Catalyzed Coupling of Quinolin-8-carboxaldehydes with CF3-Imidoyl Sulfoxonium Ylides by Chelation-Assisted C(sp2)-H Bond Activation for the Synthesis of Trifluoromethyl-Substituted Enaminones.

Pinyi Li, Zuguang Yang, Zhengkai Chen

Journal of Organic Chemistry

DOI

2024

Synthesis of Trifluoromethyl‐Containing 2,3‐Dihydrobenzofurans via a Formal [4+1] Annulation of In‐situ Generated o‑Quinone Methides and CF3‐Imidoyl Sulfoxonium Ylides

Yue-Ling Sun, Sihao Ling, Zhengkai Chen

Asian Journal of Organic Chemistry

DOI

2024

Construction of trifluoromethyl-substituted enaminones via rhodium(III)-catalyzed aldehydic C(sp2)–H bond activation of N-sulfonyl-2-aminobenzaldehydes with CF3-imidoyl sulfoxonium ylides

Yubo Duan, Zhaolin Quan, Zhengkai Chen

Tetrahedron

DOI

2024

Palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o -bromobenzoic acids for the synthesis of fused isoquinolinones

Zhaolin Quan, Yubo Duan, Zhengkai Chen

Organic Chemistry Frontiers

DOI

2024

Base‐Mediated Cascade Reaction of CF3‐Imidoyl Sulfoxonium Ylides and Diimides for the Synthesis of Functionalized Amidines

Sihao Ling, Qihua Chen, Zhengkai Chen

Advanced Synthesis & Catalysis

DOI

2024

Base-mediated formal [4+1] annulation of ortho-hydroxyphenyl substituted para-quinone methides and CF3-imidoyl sulfoxonium ylides to access trifluoroacetimidoyl-substituted 2,3-dihydrobenzofurans

Chen Li, Mingshuo Zhou, Zhengkai Chen

Journal of Fluorine Chemistry

DOI

2024

Carbonylative synthesis of 2-(trifluoromethyl)quinazolin-4(3 H )-ones from trifluoroacetimidoyl chlorides and amines based on an activated carbon fiber supported palladium catalyst

Hui Wang, Sihao Ling, Tiefeng Xu, Zhengkai Chen

New Journal of Chemistry

DOI

2023

Radical selenylative cyclization of trifluoromethyl propargyl imines for the synthesis of trifluoromethyl- and seleno-azaspiro[4,5]-tetraenones and quinolines.

G. Wei, Jia-Jun Zhang, Hao Wang, Zhengkai Chen, Xiao-Feng Wu

Organic and biomolecular chemistry

DOI

2023

Palladium-catalyzed four-component cascade carbonylative cyclization to access carbonyl-bridged bisheterocycles

Yufei Song, G. Wei, Zhaolin Quan, Zhengkai Chen, Xiao-Feng Wu

Organic Chemistry Frontiers

DOI

2023

Divergent Synthesis of Trifluoromethyl-Substituted 1,2-Dihydroquinoxalines and Diimines by Cascade Reactions of CF3-Imidoyl Sulfoxonium Ylides with Azo Compounds.

G. Wei, Dongling Zheng, Chen Li, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2023

Synthesis of ester-containing phenanthridines via photoredox-catalyzed radical cascade cyclization of N-arylacrylamides with alkyloxalyl chlorides

Mei-Jin Chen, Jian-Qiang Chen, Zhengkai Chen, Jie Wu

Organic Chemistry Frontiers

DOI

2023

Rhodium(III)-catalyzed regioselective C2-alkenylation of indoles with CF3-imidoyl sulfoxonium ylides to give multi-functionalized enamines using a migratable directing group.

Zuguang Yang, Jianhua Tang, Chen Li, Zhengkai Chen, Xiao-Feng Wu

Chemical Communications

DOI

2023

Rh(III)‐Catalyzed Cascade Cyclization of 2‐Aryl‐3H‐indoles and CF3‐Imidoyl Sulfoxonium Ylides Toward Trifluoroacetimidoyl‐Substituted 11H‐Isoindolo[2,1‐a]indoles

Zuguang Yang, Pinyi Li, Zhengkai Chen, Xiao-Feng Wu

Advanced Synthesis & Catalysis

DOI

2023

Synthesis of 5 Trifluoromethyl‐1,4‐dihydro‐1,2,4‐triazines via Base‐mediated [3 + 3] Cycloaddition of Nitrile Imines and CF3−Imidoyl Sulfoxonium Ylides

Yue Sun, Sihao Ling, Yubo Duan, Jingxian Li, Zhengkai Chen, Xiao-Feng Wu

Advanced Synthesis & Catalysis

DOI

2023

Synthesis of 5‐Trifluoromethylpyrroles from Heating‐Induced Annulation of Pyridinium 1,4‐Zwitterionic Thiolates with CF3‐Imidoyl Sulfoxonium Ylides

Sihao Ling, Yu Zhang, Zhengkai Chen, Xiao-Feng Wu

Advanced Synthesis & Catalysis

DOI

2023

Rh(III)-Catalyzed C-H/C-C Activation of Benzoylacetonitriles and Cyclization with CF3-Imidoyl Sulfoxonium Ylides to 3-Trifluoromethyl-isoquinolones

Zuguang Yang, Pinyi Li, Zhengkai Chen, Xiao-Feng Wu

Journal of Catalysis

DOI

2023

Rh(iii)-catalyzed C–H activation/annulation of N-carbamoylindoles with CF3-imidoyl sulfoxonium ylides for the divergent synthesis of trifluoromethyl-substituted (dihydro)pyrimidoindolones

Yubo Duan, Shu-Ning Lu, Zuguang Yang, Zhengkai Chen, Xiao-Feng Wu

Organic Chemistry Frontiers

DOI

2023

Catalyst‐Free, Heating‐Induced Desulfurization Annulation of CF3‐Imidoyl Sulfoxonium Ylides with Isothiocyanates for the Synthesis of 2‐Trifluoromethyl‐4‐aminoquinolines

G. Wei, Yue Sun, Dongling Zheng, Shiqi Qiu, Zhengkai Chen, Xiao-Feng Wu

Annalen der Pharmacie

DOI

2023

Carbonylative Synthesis of Fused Quinoxalinones via Palladium-Catalyzed Cascade Cyclization of 2-Heteroaryl Iodobenzene and NaN3.

Yufei Song, Zhaolin Quan, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2023

Synthesis of 2‐Trifluoromethyl‐4‐aminoquinolines via Heating‐Promoted Multi‐component Reaction of CF3‐Imidoyl Sulfoxonium Ylides and Amines with Difluorocarbene as a C1 Synthon†

G. Wei, Chen Li, Haoyuan Wang, Zhengkai Chen, Xiao-Feng Wu

Chinese journal of chemistry

DOI

2023

Construction of trifluoromethyl-containing heterocycles from trifluoroacetimidoyl chlorides and derivatives.

Zuguang Yang, G. Wei, Zhengkai Chen, Xiao-Feng Wu

Chemical Communications

DOI

2022

Metal-free synthesis of 3-trifluoromethyl-1,2,4-triazoles via oxidative cyclization of trifluoroacetimidohydrazides with N,N-dimethylformamide as carbon synthons

Shu-Ning Lu, Jia-Jun Zhang, Jingxian Li, Zhengkai Chen, Xiao-Feng Wu

Green Synthesis and Catalysis

DOI

2022

Formal [4+1] Annulation of Azoalkenes with CF3-Imidoyl Sulfoxonium Ylides and Dual Double Bond Isomerization Cascade: Synthesis of Trifluoromethyl-Containing Pyrazole Derivatives.

Yue Sun, Zuguang Yang, Shu-Ning Lu, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2022

Controllable access to trifluoromethyl-containing indoles and indolines: palladium-catalyzed regioselective functionalization of unactivated alkenes with trifluoroacetimidoyl chlorides

Hefei Yang, Le-Cheng Wang, Yu Zhang, Dongling Zheng, Zhengkai Chen, Xiao-Feng Wu

Chemical Science

DOI

2022

Heating-induced decarboxylative cyclization for the synthesis of 5-trifluoromethyl-1,2,4-triazoles from trifluoroacetimidohydrazides and α-oxocarboxylic acids

Yu Zhang, G. Wei, Shiqi Qiu, Zhengkai Chen, Xiao-Feng Wu

Green Synthesis and Catalysis

DOI

2022

Metal-free Synthesis of 5-Trifluoromethyl-1,2,4-triazoles via elemental sulfur promoted oxidative cyclization of trifluoroacetimidohydrazides with benzylic and aliphatic amines

Shu-Ning Lu, Yue Sun, Jia-Jun Zhang, Zhengkai Chen, Xiao-Feng Wu

Molecular Catalysis

DOI

2022

Metal-free synthesis of 3-trifluoromethyl-1,2,4-triazoles via multi-component reaction of trifluoroacetimidoyl chlorides, hydrazine hydrate and benzene-1,3,5-triyl triformate

Bin-Jie Wang, Yue Sun, Anderson Cheng, Ye Zhu, Ji-Ye Wang, Zhengkai Chen, Xiao-Feng Wu

Frontiers in Chemistry

DOI

2022

Ruthenium-Catalyzed Hydroxyl-Directed peri-Selective C-H Activation and Annulation of 1-Naphthols with CF3-Imidoyl Sulfoxonium Ylides for the Synthesis of 2-(Trifluoromethyl)-2,3-dihydrobenzo[de]chromen-2-amines.

Zuguang Yang, Jianhua Tang, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2022

Rh(III)-Catalyzed Dual C-H Activation/Cascade Annulation of Benzimidates and CF3-Imidoyl Sulfoxonium Ylides for the Synthesis of Trifluoromethyl-Decorated Benzo[de][1,8]naphthyridines.

Yu Zhang, Sihao Ling, Pinyi Li, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2022

Recent Advances in Copper‐Catalyzed Carboxylation Reactions with CO2

Yu‐Fei Song, Yu Zhang, Zhengkai Chen, Xiao‐Feng Wu

Asian Journal of Organic Chemistry

DOI

2022

Palladium-catalyzed norbornene-mediated dehydrogenative annulation of 3-iodochromones with trifluoroacetimidoyl chlorides for the construction of trifluoromethyl-substituted chromeno[2,3-c]quinolin-12-ones

Jianhua Tang, Zuguang Yang, Yu‐Fei Song, Zhengkai Chen, Xiao‐Feng Wu

Molecular Catalysis

DOI

2022

Copper‐Catalyzed Decarbonylative Cyclization of Isatins and Trifluoroacetimidohydrazides for the Synthesis of 2‐(5‐Trifluoromethyl‐1,2,4‐triazol‐3‐yl)anilines

Yu Zhang, Zuguang Yang, Zhengkai Chen, Leifang Liu, Xiao‐Feng Wu

Advanced Synthesis & Catalysis

DOI

2021

Synthesis of 5-trifluoromethyl-1,2,3-triazoles via base-mediated cascade annulation of diazo compounds with trifluoroacetimidoyl chlorides

Hefei Yang, Tianyang Xu, Shu-Ning Lu, Zhengkai Chen, Xiao-Feng Wu

DOI

2021

The cascade coupling/iodoaminocyclization reaction of trifluoroacetimidoyl chlorides and allylamines: metal-free access to 2-trifluoromethyl-imidazolines.

Yufei Song, Le-Cheng Wang, Shiying Du, Zhengkai Chen, Xiao-Feng Wu

Organic and biomolecular chemistry

DOI

2021

Palladium-Catalyzed Cascade Carbonylative Synthesis of 1,2,4-Triazol-3-ones from Hydrazonoyl Chlorides and NaN3.

Shiying Du, Wei-Feng Wang, Yufei Song, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2021

Palladium-catalyzed carbonylative synthesis of 5-trifluoromethyl-1,2,4-triazoles from trifluoroacetimidohydrazides and aryl iodides

Jianhua Tang, Jia-Jun Zhang, Yu Zhang, Zhengkai Chen, Xiao-Feng Wu

Organic Chemistry Frontiers

DOI

2021

Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles via Metal‐Free Annulation of Trifluoroacetimidohydrazides and Methyl Ketones

Jia-Jun Zhang, Jianhua Tang, Zhengkai Chen, Xiao-Feng Wu

Advanced Synthesis and Catalysis

DOI

2021

TFBen (Benzene‐1,3,5‐triyl triformate): A Powerful and Versatile CO Surrogate

Hefei Yang, Jia-Jun Zhang, Zhengkai Chen, Xiao-Feng Wu

The chemical record

DOI

2021

Elemental Sulfur and Dimethyl Sulfoxide‐Promoted Oxidative Cyclization of Trifluoroacetimidohydrazides with Methylhetarenes for the Synthesis of 3‐Hetaryl ‐5‐trifluoromethyl‐1,2,4‐triazoles

Jia-Jun Zhang, Jianhua Tang, Zhengkai Chen, Xiao-Feng Wu

Chinese journal of chemistry

DOI

2021

Copper-mediated [3 + 2] cycloaddition of trifluoroacetimidoyl chlorides and N-isocyanoiminotriphenylphosphorane for the synthesis of 3-trifluoromethyl-1,2,4-triazoles

Hefei Yang, Shu-Ning Lu, Yufei Song, Zhengkai Chen, Xiao-Feng Wu

Organic Chemistry Frontiers

DOI

2021

Silver-Mediated [3 + 2] Cycloaddition of Azomethine Ylides with Trifluoroacetimidoyl Chlorides for the Synthesis of 5-(Trifluoromethyl)imidazoles.

Hefei Yang, Shu-Ning Lu, Zhengkai Chen, Xiao-Feng Wu

Journal of Organic Chemistry

DOI

2021

Metal-free oxidative cyclization of trifluoroacetimidohydrazides with methylhetarenes: a facile access to 3-hetaryl-5-trifluoromethyl-1,2,4-triazoles

Jia-Jun Zhang, Tianxiang Xu, Zhengkai Chen, Xiao-Feng Wu

DOI

2021

Oxidative Cyclization of Trifluoroacetimidohydrazides with D‐Glucose for the Metal‐Free Synthesis of 3‐Trifluoromethyl‐1,2,4‐Triazoles

Shu-Ning Lu, Hefei Yang, Jia-Jun Zhang, Zhengkai Chen, Xiao-Feng Wu

Advanced Synthesis and Catalysis

DOI

2021

Palladium‐Catalyzed Carbonylative Synthesis of 2‐(Trifluoromethyl)quinazolin‐4(3 H )‐ones from Trifluoroacetimidoyl Chlorides and Nitro Compounds

Le-Cheng Wang, Yu Zhang, Zhengkai Chen, Xiao-Feng Wu

Advanced Synthesis and Catalysis

DOI

2021

Efficient synthesis of 2-trifluoromethyl-benzimidazoles via cascade annulation of trifluoroacetimidoyl chlorides and amines based on a heterogeneous copper doped g-C3N4 catalyst

Tie-Feng Xu, Yu Zhang, Li-Li Yi, Wangyang Lu, Zhengkai Chen, Xiao-Feng Wu

Molecular Catalysis

DOI

2021

Synthesis of 3H-1,2,4-Triazol-3-ones via NiCl2-Promoted Cascade Annulation of Hydrazonoyl Chlorides and Sodium Cyanate.

Shiying Du, Zu-Guang Yang, Jianhua Tang, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2020

FeCl3-Mediated Synthesis of 2-(Trifluoromethyl)quinazolin-4(3H)-ones from Isatins and Trifluoroacetimidoyl Chlorides.

Le-Cheng Wang, Shiying Du, Zhengkai Chen, Xiao-Feng Wu

Organic Letters

DOI

2020

Carbonylative synthesis of heterocycles involving diverse CO surrogates.

Zhengkai Chen, Le-Cheng Wang, Xiao-Feng Wu

Chemical Communications

DOI

2020

Palladium-catalyzed three-component carbonylative synthesis of 2-(trifluoromethyl)quinazolin-4(3H)-ones from trifluoroacetimidoyl chlorides and amines

Zhengkai Chen, Le-Cheng Wang, Jia-Jun Zhang, Xiao-Feng Wu

DOI

2020

Base-mediated [3+2] annulation of trifluoroacetimidoyl chlorides and isocyanides: An improved approach for regioselective synthesis of 5-trifluoromethyl-imidazoles

Sipei Hu, Hefei Yang, Zhengkai Chen, Xiao-Feng Wu

DOI

2020

Trifluoroacetimidoyl halides: a potent synthetic origin

Zhengkai Chen, Sipei Hu, Xiao-Feng Wu

DOI

2020

A Convenient FeCl 3 ‐Mediated Synthesis of 5‐Trifluoromethyl‐1,2,4‐triazoles from Trifluoroacetimidoyl Chlorides and Hydrazides

Shiying Du, Le-Cheng Wang, Zu-Guang Yang, Zhengkai Chen, Xiao-Feng Wu

DOI

2020

Palladium-Catalyzed Four-Component Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides, Propargyl Amines, and Diaryliodonium Salts: Access to Trifluoromethyl-Containing Trisubstituted Imidazoles.

Zhengkai Chen, Wei-Feng Wang, Hefei Yang, Xiao-Feng Wu

Organic Letters

DOI

2020

Palladium‐Catalyzed Cascade Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides and 2‐Iodoanilines: Toward 2‐(Trifluoromethyl)quinazolin‐4(3H)‐ones Synthesis

Hefei Yang, Le-Cheng Wang, Wei-Feng Wang, Zhengkai Chen, Xiao-Feng Wu

ChemistrySelect

DOI

2019

Metal‐Free Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles from Iodine‐Mediated Annulation of Trifluoroacetimidoyl Chlorides and Hydrazones

Sipei Hu, Zu-Guang Yang, Zhengkai Chen, Xiao-Feng Wu

Advanced Synthesis and Catalysis

DOI

2016

ChemInform Abstract: I2‐Catalyzed Oxidative Coupling Reactions of Hydrazones and Amines and the Application in the Synthesis of 1,3,5‐Trisubstituted 1,2,4‐Triazoles.

Zhengkai Chen, Hongli Li, Weipeng Dong, Maozhong Miao, Hongjun Ren

ChemInform

DOI

2016

ChemInform Abstract: Synthesis of Benzo‐Fused Cyclic Compounds via Intramolecular Cyclization of Aryltriazenes

Weipeng Dong, Zhengkai Chen, Jianfeng Xu, Maozhong Miao, Hongjun Ren

ChemInform

DOI

2016

ChemInform Abstract: Nickel‐Catalyzed Regioselective Reductive Cross‐Coupling of Aryl Halides with Polysubstituted Allyl Halides in the Presence of Imidazolium Salts.

Zhan Zhang, Lijun Xu, Zhengkai Chen, Zhubo Liu, Maozhong Miao, Jinyu Song, Hongjun Ren

ChemInform

DOI

2015

铜和碘促进的1,2,3-三氮唑合成研究

陈铮凯

《浙江大学》

2013

ChemInform Abstract: Ru‐Catalyzed Synthesis of Dihydrofuroquinolines from Azido‐cyclopropyl Ketones.

Weijun Yang, Lijun Xu, Zhengkai Chen, Lili Zhang, Maozhong Miao, Hongjun Ren

ChemInform

DOI

精选作品

期刊论文

Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles via Palladium‐Catalyzed [4 + 1] Oxidative Annulation of Trifluoroacetimidohydrazides and Isocyanides

Rh(III)-Catalyzed Multicomponent Cascade Reaction of 2-Arylimidazo[1,2- a ]pyridines with CF3-Imidoyl Sulfoxonium Ylides via Multiple C–H Activation

Rapid Assembly of Trifluoromethyl‐Substituted Thiazolidine‐2‐Thiones via [3 + 2] Annulation of Dithiocarbamate Salts with CF 3 ‐Imidoyl Sulfoxonium Ylides Under Mild Conditions

Metal‐Free Synthesis of 3‐Trifluoromethyl‐1,2,4‐triazoles via [4+1] Cyclization of Trifluoroacetimidohydrazides With BrCF 2 COOEt as a C1 Synthon

Rhodium(III)-Catalyzed C–H Bond Activation and [3+3] Spirocyclization of Benzoxazines with CF 3 -Imidoyl Sulfoxonium Ylides toward Trifluoromethyl-Substituted Spiroheterocyclic Compounds

Condition-controlled Rh( iii )-catalyzed C–H activation and annulation of 1-aryl-5-aminopyrazoles with CF 3 -imidoyl sulfoxonium ylides for the divergent synthesis of trifluoromethyl-functionalized pyrazole-fused heterocycles

Heating-induced cascade annulation of CF 3 -imidoyl sulfoxonium ylides with thioamides for the synthesis of multi-substituted imidazolines via sulfur and acyl migration

Catalyst‐Controlled Cascade Annulation of CF 3 ‐Imidoyl Sulfoxonium Ylides with Activated Nitriles for the Divergent Synthesis of Trifluoromethyl‐Substituted Pyrroles and Quinolines

Synthesis of Trifluoromethyl‐Substituted Tetrazoles via KI/TBHP‐Mediated Oxidative Annulation of Trifluoroacetimidohydrazides and Nitromethane

Synthesis of 2-Trifluoromethylindolines via Rh(III)-Catalyzed Chelation-Assisted C–H Bond Activation and Annulation of Anilines with CF 3 -Imidoyl Sulfoxonium Ylides

Synthesis of Spiro 3,3′-Cyclopropyl Oxindoles via Cyclopropanation of 3-Alkenyl-oxindoles with CF3-Imidoyl Sulfoxonium Ylides

Rh(III)‐Catalyzed C(sp 2 )–H and C(sp 2 )–C(sp 2 ) Bond Activation of Aryl Oximes with CF 3 ‐Imidoyl Sulfoxonium Ylides: Access to N ‐(2‐Cyanoaryl)‐3‐(Trifluoromethyl)isoquinolin‐1( 2H )‐Imines

Rh( iii )-catalyzed annulation of oxadiazolones with CF 3 -imidoyl sulfoxonium ylides: access to trifluoromethyl-substituted fused-dihydroisoquinolines

Synthesis of trifluoromethyl-functionalized benzo[ de ][1,8]naphthyridines via Rh( iii )-catalyzed two-fold C–H activation of benzamidine hydrochlorides and annulation with CF 3 -imidoyl sulfoxonium ylides

强化学术牵引，深化科教融合：创新化学本科人才培养的探索与实践

Rhodium(III)-Catalyzed Coupling of Quinolin-8-carboxaldehydes with CF3-Imidoyl Sulfoxonium Ylides by Chelation-Assisted C(sp2)-H Bond Activation for the Synthesis of Trifluoromethyl-Substituted Enaminones.

Synthesis of Trifluoromethyl‐Containing 2,3‐Dihydrobenzofurans via a Formal [4+1] Annulation of In‐situ Generated o‑Quinone Methides and CF3‐Imidoyl Sulfoxonium Ylides

Construction of trifluoromethyl-substituted enaminones via rhodium(III)-catalyzed aldehydic C(sp2)–H bond activation of N-sulfonyl-2-aminobenzaldehydes with CF3-imidoyl sulfoxonium ylides

Palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o -bromobenzoic acids for the synthesis of fused isoquinolinones

Base‐Mediated Cascade Reaction of CF3‐Imidoyl Sulfoxonium Ylides and Diimides for the Synthesis of Functionalized Amidines

Base-mediated formal [4+1] annulation of ortho-hydroxyphenyl substituted para-quinone methides and CF3-imidoyl sulfoxonium ylides to access trifluoroacetimidoyl-substituted 2,3-dihydrobenzofurans

Carbonylative synthesis of 2-(trifluoromethyl)quinazolin-4(3 H )-ones from trifluoroacetimidoyl chlorides and amines based on an activated carbon fiber supported palladium catalyst

Radical selenylative cyclization of trifluoromethyl propargyl imines for the synthesis of trifluoromethyl- and seleno-azaspiro[4,5]-tetraenones and quinolines.

Palladium-catalyzed four-component cascade carbonylative cyclization to access carbonyl-bridged bisheterocycles

Divergent Synthesis of Trifluoromethyl-Substituted 1,2-Dihydroquinoxalines and Diimines by Cascade Reactions of CF3-Imidoyl Sulfoxonium Ylides with Azo Compounds.

Synthesis of ester-containing phenanthridines via photoredox-catalyzed radical cascade cyclization of N-arylacrylamides with alkyloxalyl chlorides

Rhodium(III)-catalyzed regioselective C2-alkenylation of indoles with CF3-imidoyl sulfoxonium ylides to give multi-functionalized enamines using a migratable directing group.

Rh(III)‐Catalyzed Cascade Cyclization of 2‐Aryl‐3H‐indoles and CF3‐Imidoyl Sulfoxonium Ylides Toward Trifluoroacetimidoyl‐Substituted 11H‐Isoindolo[2,1‐a]indoles

Synthesis of 5 Trifluoromethyl‐1,4‐dihydro‐1,2,4‐triazines via Base‐mediated [3 + 3] Cycloaddition of Nitrile Imines and CF3−Imidoyl Sulfoxonium Ylides

Synthesis of 5‐Trifluoromethylpyrroles from Heating‐Induced Annulation of Pyridinium 1,4‐Zwitterionic Thiolates with CF3‐Imidoyl Sulfoxonium Ylides

Rh(III)-Catalyzed C-H/C-C Activation of Benzoylacetonitriles and Cyclization with CF3-Imidoyl Sulfoxonium Ylides to 3-Trifluoromethyl-isoquinolones

Rh(iii)-catalyzed C–H activation/annulation of N-carbamoylindoles with CF3-imidoyl sulfoxonium ylides for the divergent synthesis of trifluoromethyl-substituted (dihydro)pyrimidoindolones

Catalyst‐Free, Heating‐Induced Desulfurization Annulation of CF3‐Imidoyl Sulfoxonium Ylides with Isothiocyanates for the Synthesis of 2‐Trifluoromethyl‐4‐aminoquinolines

Carbonylative Synthesis of Fused Quinoxalinones via Palladium-Catalyzed Cascade Cyclization of 2-Heteroaryl Iodobenzene and NaN3.

Synthesis of 2‐Trifluoromethyl‐4‐aminoquinolines via Heating‐Promoted Multi‐component Reaction of CF3‐Imidoyl Sulfoxonium Ylides and Amines with Difluorocarbene as a C1 Synthon†

Construction of trifluoromethyl-containing heterocycles from trifluoroacetimidoyl chlorides and derivatives.

Metal-free synthesis of 3-trifluoromethyl-1,2,4-triazoles via oxidative cyclization of trifluoroacetimidohydrazides with N,N-dimethylformamide as carbon synthons

Formal [4+1] Annulation of Azoalkenes with CF3-Imidoyl Sulfoxonium Ylides and Dual Double Bond Isomerization Cascade: Synthesis of Trifluoromethyl-Containing Pyrazole Derivatives.

Controllable access to trifluoromethyl-containing indoles and indolines: palladium-catalyzed regioselective functionalization of unactivated alkenes with trifluoroacetimidoyl chlorides

Heating-induced decarboxylative cyclization for the synthesis of 5-trifluoromethyl-1,2,4-triazoles from trifluoroacetimidohydrazides and α-oxocarboxylic acids

Metal-free Synthesis of 5-Trifluoromethyl-1,2,4-triazoles via elemental sulfur promoted oxidative cyclization of trifluoroacetimidohydrazides with benzylic and aliphatic amines

Metal-free synthesis of 3-trifluoromethyl-1,2,4-triazoles via multi-component reaction of trifluoroacetimidoyl chlorides, hydrazine hydrate and benzene-1,3,5-triyl triformate

Ruthenium-Catalyzed Hydroxyl-Directed peri-Selective C-H Activation and Annulation of 1-Naphthols with CF3-Imidoyl Sulfoxonium Ylides for the Synthesis of 2-(Trifluoromethyl)-2,3-dihydrobenzo[de]chromen-2-amines.

Rh(III)-Catalyzed Dual C-H Activation/Cascade Annulation of Benzimidates and CF3-Imidoyl Sulfoxonium Ylides for the Synthesis of Trifluoromethyl-Decorated Benzo[de][1,8]naphthyridines.

Recent Advances in Copper‐Catalyzed Carboxylation Reactions with CO2

Palladium-catalyzed norbornene-mediated dehydrogenative annulation of 3-iodochromones with trifluoroacetimidoyl chlorides for the construction of trifluoromethyl-substituted chromeno[2,3-c]quinolin-12-ones

Copper‐Catalyzed Decarbonylative Cyclization of Isatins and Trifluoroacetimidohydrazides for the Synthesis of 2‐(5‐Trifluoromethyl‐1,2,4‐triazol‐3‐yl)anilines

Synthesis of 5-trifluoromethyl-1,2,3-triazoles via base-mediated cascade annulation of diazo compounds with trifluoroacetimidoyl chlorides

The cascade coupling/iodoaminocyclization reaction of trifluoroacetimidoyl chlorides and allylamines: metal-free access to 2-trifluoromethyl-imidazolines.

Palladium-Catalyzed Cascade Carbonylative Synthesis of 1,2,4-Triazol-3-ones from Hydrazonoyl Chlorides and NaN3.

Palladium-catalyzed carbonylative synthesis of 5-trifluoromethyl-1,2,4-triazoles from trifluoroacetimidohydrazides and aryl iodides

Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles via Metal‐Free Annulation of Trifluoroacetimidohydrazides and Methyl Ketones

TFBen (Benzene‐1,3,5‐triyl triformate): A Powerful and Versatile CO Surrogate

Elemental Sulfur and Dimethyl Sulfoxide‐Promoted Oxidative Cyclization of Trifluoroacetimidohydrazides with Methylhetarenes for the Synthesis of 3‐Hetaryl ‐5‐trifluoromethyl‐1,2,4‐triazoles

Copper-mediated [3 + 2] cycloaddition of trifluoroacetimidoyl chlorides and N-isocyanoiminotriphenylphosphorane for the synthesis of 3-trifluoromethyl-1,2,4-triazoles

Silver-Mediated [3 + 2] Cycloaddition of Azomethine Ylides with Trifluoroacetimidoyl Chlorides for the Synthesis of 5-(Trifluoromethyl)imidazoles.

Metal-free oxidative cyclization of trifluoroacetimidohydrazides with methylhetarenes: a facile access to 3-hetaryl-5-trifluoromethyl-1,2,4-triazoles

Oxidative Cyclization of Trifluoroacetimidohydrazides with D‐Glucose for the Metal‐Free Synthesis of 3‐Trifluoromethyl‐1,2,4‐Triazoles

Palladium‐Catalyzed Carbonylative Synthesis of 2‐(Trifluoromethyl)quinazolin‐4(3 H )‐ones from Trifluoroacetimidoyl Chlorides and Nitro Compounds

Efficient synthesis of 2-trifluoromethyl-benzimidazoles via cascade annulation of trifluoroacetimidoyl chlorides and amines based on a heterogeneous copper doped g-C3N4 catalyst

Synthesis of 3H-1,2,4-Triazol-3-ones via NiCl2-Promoted Cascade Annulation of Hydrazonoyl Chlorides and Sodium Cyanate.

FeCl3-Mediated Synthesis of 2-(Trifluoromethyl)quinazolin-4(3H)-ones from Isatins and Trifluoroacetimidoyl Chlorides.

Carbonylative synthesis of heterocycles involving diverse CO surrogates.

Palladium-catalyzed three-component carbonylative synthesis of 2-(trifluoromethyl)quinazolin-4(3H)-ones from trifluoroacetimidoyl chlorides and amines

Base-mediated [3+2] annulation of trifluoroacetimidoyl chlorides and isocyanides: An improved approach for regioselective synthesis of 5-trifluoromethyl-imidazoles

Trifluoroacetimidoyl halides: a potent synthetic origin

A Convenient FeCl 3 ‐Mediated Synthesis of 5‐Trifluoromethyl‐1,2,4‐triazoles from Trifluoroacetimidoyl Chlorides and Hydrazides

Palladium-Catalyzed Four-Component Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides, Propargyl Amines, and Diaryliodonium Salts: Access to Trifluoromethyl-Containing Trisubstituted Imidazoles.

Palladium‐Catalyzed Cascade Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides and 2‐Iodoanilines: Toward 2‐(Trifluoromethyl)quinazolin‐4(3H)‐ones Synthesis

Metal‐Free Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles from Iodine‐Mediated Annulation of Trifluoroacetimidoyl Chlorides and Hydrazones

ChemInform Abstract: I2‐Catalyzed Oxidative Coupling Reactions of Hydrazones and Amines and the Application in the Synthesis of 1,3,5‐Trisubstituted 1,2,4‐Triazoles.

ChemInform Abstract: Synthesis of Benzo‐Fused Cyclic Compounds via Intramolecular Cyclization of Aryltriazenes

ChemInform Abstract: Nickel‐Catalyzed Regioselective Reductive Cross‐Coupling of Aryl Halides with Polysubstituted Allyl Halides in the Presence of Imidazolium Salts.

铜和碘促进的1,2,3-三氮唑合成研究

ChemInform Abstract: Ru‐Catalyzed Synthesis of Dihydrofuroquinolines from Azido‐cyclopropyl Ketones.

会议论文

廉价金属催化的C-N键构筑及杂环合成

基于过渡金属催化的杂环化合物的合成