肖斌｜重庆医科大学｜学者主页

2026

表观遗传修饰在乳腺癌可塑性和药物治疗抵抗中的作用

肖雨晗，向芹，张宏特，陈中午，吴顺红，肖斌，李林海

《分子诊断与治疗杂志》

DOI

2025

N4-乙酰胞苷修饰的基本特征及其在肿瘤进展和治疗中的作用

柘钞，赵峻秀，方嘉雯，刘水平，张雨芊，李林海，肖斌

《中国医学前沿杂志(电子版)》

2025

RNA修饰相互作用的分子机制及其在肿瘤诊疗中的作用

方嘉雯，柘钞，徐玲婷，李林海，肖斌

《生物化学与生物物理进展》

2025

CircABCA1 promotes ccRCC by reprogramming cholesterol metabolism and facilitating M2 macrophage polarization through IGF2BP3-mediated stabilization of SCARB1 mRNA

Hao Ning, Yan Jiang, Binbin Li, Junwu Ren, Cong Wang, Ling Wei, Linfei Li, Ai Ran, Zu-Mao Li, Jiao Li, Wei Li, Yong-Quan Wang, Bin Xiao

Molecular Cancer

DOI

2025

FNDC3B promotes gastric cancer metastasis via interacting with FAM83H and preventing its proteasomal degradation

Yuying Zhang, Lingyu Ran, Yuying Liu, Wei Li, Ai Ran, Hai-Ping Li, Bo Huang, Junwu Ren, Hao Ning, Qiang Ma, Xiaolin Wang, Feifei Yang, Xiaojuan Pan, Ce Liang, Shiming Wang, Changhong Qin, Yan Jiang, Kun Qian, Bin Xiao

Cellular & Molecular Biology Letters

DOI

2025

Targeted delivery of circPDHK1 siRNA via aptamer functionalized lipid nanoparticles inhibits ccRCC growth and migration.

Hao Ning, Yan Jiang, Binbin Li, Junwu Ren, Ai Ran, Wei Li, Bin Xiao

International journal of pharmaceutics

DOI

2024

Circ-0007766作为miR-1972海绵调控HER2表达促进乳腺癌细胞迁移和侵袭

赵峻秀，朱艺，宋筱羽，柘钞，肖雨晗，刘云多，李林海，肖斌

《中国癌症杂志》

2024

血清lncRNA T342620联合AFP对肝癌的诊断价值

陈敏，张卫云，徐宗琴，肖斌，刘娟子，李晓，孙朝晖

《国际检验医学杂志》

2024

RNA-binding protein IGF2BP2 suppresses metastasis of clear cell renal cell carcinoma by enhancing CKB mRNA stability and expression

Junwu Ren, Bo Huang, Wei Li, Yong-Quan Wang, Xiaojuan Pan, Qiang Ma, Yuying Liu, Xiaolin Wang, Ce Liang, Yuying Zhang, Shiming Wang, Feifei Yang, Hai-Ping Li, Hao Ning, Yan Jiang, Changhong Qin, Ai Ran, Bin Xiao

Translational Oncology

DOI

2024

Identification of Plasma hsa_circ_0001230 and hsa_circ_0023879 as Potential Novel Biomarkers for Focal Segmental Glomerulosclerosis and circRNA-miRNA-mRNA Network Analysis

Lingyu Ran, Wei Li, Hu-Hai Zhang, Jie Lin, Longyin Zhu, Huanping Long, Lunli Xiang, Liping Chen, Qi-Xuan Li, Yu-Han Hu, M. Gong, Bin Xiao, Hong-Wen Zhao

Kidney & Blood Pressure Research

DOI

2024

Emerging roles of circular RNAs in tumorigenesis, progression, and treatment of gastric cancer

Qiang Ma, Feifei Yang, Bin Xiao, Xiao-Lan Guo

Journal of Translational Medicine

DOI

2024

A novel protein FNDC3B-267aa encoded by circ0003692 inhibits gastric cancer metastasis via promoting proteasomal degradation of c-Myc

Yuying Liu, Yuying Zhang, Lingyu Ran, Bo Huang, Junwu Ren, Qiang Ma, Xiaojuan Pan, Feifei Yang, Ce Liang, Xiaolin Wang, Shiming Wang, Ai Ran, Hao Ning, Yan Jiang, Changhong Qin, Bin Xiao

Journal of Translational Medicine

DOI

2024

Construction of dual functional CuAl-LDHs nanocomposite loaded with IGF2BP3 siRNA for enhanced therapy of gastric cancer

Haiping Li, Yuying Zhang, Bo Huang, Feifei Yang, Qiang Ma, Xiaolin Wang, Yuying Liu, Junwu Ren, Xiaojuan Pan, Ce Liang, Shiming Wang, Hao Ning, Changhong Qin, Yan Jiang, Ai Ran, Bin Xiao

Chemical Engineering Journal

DOI

2024

A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway

Bo Huang, Junwu Ren, Qiang Ma, Feifei Yang, Xiaojuan Pan, Yuying Zhang, Yuying Liu, Cong Wang, Dawei Zhang, Ling Wei, Lingyu Ran, Hong-Wen Zhao, Ce Liang, Xiaolin Wang, Shiming Wang, Hai-Ping Li, Hao Ning, Ai Ran, Wei Li, Yong-Quan Wang, Bin Xiao

Molecular Cancer

DOI

2024

PTBP1 knockdown impairs autophagy flux and inhibits gastric cancer progression through TXNIP-mediated oxidative stress

Shiming Wang, Xiaolin Wang, Changhong Qin, Ce Liang, Wei Li, Ai Ran, Qiang Ma, Xiaojuan Pan, Feifei Yang, Junwu Ren, Bo Huang, Yuying Liu, Yuying Zhang, Hai-Ping Li, Hao Ning, Yan Jiang, Bin Xiao

Cellular & Molecular Biology Letters

DOI

2024

RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA

Xiaolin Wang, Ce Liang, Shiming Wang, Qiang Ma, Xiaojuan Pan, Ai Ran, Changhong Qin, Bo Huang, Feifei Yang, Yuying Liu, Yuying Zhang, Junwu Ren, Hao Ning, Hai-Ping Li, Yan Jiang, Bin Xiao

Cells

DOI

2023

CircNFATC3 promotes the proliferation of gastric cancer through binding to IGF2BP3 and restricting its ubiquitination to enhance CCND1 mRNA stability

Feifei Yang, Qiang Ma, Bo Huang, Xiaolin Wang, Xiaojuan Pan, Ting Yu, Lingyu Ran, Shan Jiang, Haiping Li, Ye Chen, Yuying Liu, Ce Liang, Junwu Ren, Yuying Zhang, Shimin Wang, Wei Li, Bin Xiao

Journal of Translational Medicine

DOI

2022

Circ-0003910在HER2阳性乳腺癌中的表达、定位、生物学作用及蛋白质组学研究

朱艺，肖斌，刘嘉慧，黄玲，孙朝晖，李林海

《中国癌症杂志》

2022

CBL通过泛素化降解NCK2抑制乳腺癌细胞的增殖和侵袭

宋筱羽，肖斌，陆景润，张文武，李锦潮，竹昕，孙朝晖，李林海

《南方医科大学学报》

2022

基于CRISPR/Cas13a技术检测肿瘤驱动基因TP53 R248W的研究

邝振展，肖斌，孙朝晖，罗镕，何洁雯，李林海

《南京医科大学学报(自然科学版)》

2022

乳腺癌组织miR-381和跨膜蛋白16A表达与临床病理特征及预后的关系

柯永莉，李黎，寇晓梅，李燕，喻兰雅，肖斌

《中华实用诊断与治疗杂志》

2022

Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA

Xiaojuan Pan, Bo Huang, Qiang Ma, Junwu Ren, Yuying Liu, Cong Wang, Dawei Zhang, Jian Fu, Lingyu Ran, Ting Yu, Haiping Li, Xiaolin Wang, Feifei Yang, Ce Liang, Yuying Zhang, Shimin Wang, Jingjing Ren, Wei Li, Yongquan Wang, Bin Xiao

Clinical and Translational Medicine

DOI

2022

CircARID1A binds to IGF2BP3 in gastric cancer and promotes cancer proliferation by forming a circARID1A-IGF2BP3-SLC7A5 RNA–protein ternary complex

Qiang Ma, Feifei Yang, Bo Huang, Xiaojuan Pan, Wei Li, Ting Yu, Xiaolin Wang, Lingyu Ran, Kun Qian, Hui Li, Haiping Li, Yuying Liu, Ce Liang, Junwu Ren, Yuying Zhang, Shimin Wang, Bin Xiao

Journal of Experimental & Clinical Cancer Research

DOI

2021

NR2F6在肿瘤中的研究进展

黄玲，刘嘉慧，朱艺，周泉，肖斌，孙朝晖，李林海

《生物工程学报》

2021

锌指蛋白家族的转录调控模式及其对肿瘤细胞发展进程的影响

张文武，肖斌，宋筱羽，孙朝晖，李林海

《东南大学学报(医学版)》

2021

Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL

Ting Yu, Lingyu Ran, Hongwen Zhao, Pin Yin, Wei Li, Jie Lin, Hui Mao, Dongping Cai, Qiang Ma, Xiaojuan Pan, Xiaolin Wang, Jingjing Wu, Hao Zeng, Weijun Zhang, Dongshui Lu, Ping Luo, Quanming Zou, Bin Xiao

Molecular Therapy — Nucleic Acids

DOI

2020

研究生肿瘤分子生物学实验课程的改革

陈川宁，张春燕，肖斌，甘淋

《教育教学论坛》

2020

乳腺癌组织CBL-B蛋白表达与生物学行为和预后关系

邓淳，肖斌，李纬玮，陆景润，李林海，莫非

《中华肿瘤防治杂志》

DOI

2020

立足交叉学科特色推进医学研究生肿瘤分子生物学课程的改革

肖斌，张春燕，甘淋

《学园》

2020

Casitas B系淋巴瘤原癌基因在乳腺癌组织中的表达水平及其临床预后分析

陆景润，肖斌，邓淳，李纬玮，李林海，黄健，张姝

《医学研究与战创伤救治》

DOI

2020

CBLC在各分型分期乳腺癌中的表达差异及预后分析

李纬玮，肖斌，陆景润，邓淳，李林海，罗昭逊

《安徽医科大学学报》

DOI

2020

miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells

Xingju Zhang, Fei Li, Ying Tang, Ren Qinglan, Bin Xiao, Ying Wan, Shan Jiang

Oncogene

DOI

2020

MiR-30a suppresses metastasis of gastric adenocarcinoma via targeting FAPα

Ting Yu, Li Gong, Wei Li, Qianfei Zuo, Dongping Cai, Hui Mao, Lina Wang, Jie Lin, Bin Xiao

Cancer Biomarkers

DOI

2020

Identification of plasma miR-106a-5p and miR-30a-5p as potential biomarkers for mesangial proliferative glomerulonephritis

Lina Wang, Jie Lin, Ting Yu, Qianfei Zuo, Bingbing Shen, Huhai Zhang, Baolian Liu, Dongping Cai, Hui Mao, Hongwen Zhao, Quanming Zou, Bin Xiao

Clinical Biochemistry

DOI

2019

稳定表达人源GRM4基因的乳腺癌细胞株的筛选及鉴定

林志坚，肖斌，孙朝晖，李林海

《实用癌症杂志》

2019

CRISPR/Cas9文库筛选技术的发展及在肿瘤研究中的应用

雷婷，肖斌，何咏茵，曲璟，孙朝晖，李林海

《南方医科大学学报》

2019

Plasma circular RNA panel acts as a novel diagnostic biomarker for colorectal cancer

Jie Lin, Dongping Cai, Wěi Li, Ting Yu, Hui Mao, Shan Jiang, Bin Xiao

Clinical Biochemistry

DOI

2018

GRM4正向别构调节剂抑制乳腺癌细胞的增殖并促进细胞凋亡

李林海，肖斌，郭梓璇，赖斯华，古丽米热·安外尔，符玉文，陈建芸，孙朝晖

《中国癌症杂志》

2018

Luminal亚型乳腺癌细胞与正常乳腺细胞的circRNA表达谱差异分析

肖斌，温嘉欣，赵超然，陈丽丹，孙朝晖，李林海

《南方医科大学学报》

2018

稳定表达GRIK3乳腺癌MDA-MB-231细胞株的筛选及鉴定

吴伊雪，肖斌，孙朝晖，陈丽丹，黄晓燕，李林海

《临床肿瘤学杂志》

2017

翻译调控肿瘤蛋白的结构、功能以及在肿瘤发展中的作用

肖斌，阳正盟，肖鸣，陈昊，马强

《生物化学与生物物理进展》

2015

长非编码RNA在基因调控和肿瘤形成中的作用

李笋，左钱飞，李俊林，曹力尹，肖斌

《现代生物医学进展》

2014

RNAi基因沉默对消化系统肿瘤化疗敏感性的影响

邵军，余文静，肖斌，曾凡才

《重庆医学》

2014

miRNA对T细胞分化与功能的调节作用

余婷，肖斌

《生命的化学》

DOI

2013

miR-25在人胃癌组织中的表达分析及其靶基因TOB1的鉴定

黎伯胜，左钱飞，肖斌，邹全明，郭刚

《中国肿瘤临床》

2011

幽门螺杆菌感染细胞模型的建立及感染相关microRNAs的筛选鉴定

刘真，贾赤宇，肖斌，唐彬，黎伯胜，毛旭虎，邹全明

《现代生物医学进展》

2010

microRNA在胃肠道肿瘤中的研究进展

黎伯胜，肖斌，刘真，邹全明

《中国肿瘤临床》

2010

miRNA在细胞因子表达调控中的作用

李娜，肖斌，邹全明，毛旭虎

《生命的化学》

2009

Mirtron——miRNA合成的新途径

唐彬，肖斌，邹全明，毛旭虎

《生命的化学》

2009

炎症与肿瘤的关系研究进展

刘真，肖斌，毛旭虎，邹全明

《现代生物医学进展》

精选作品

期刊论文

表观遗传修饰在乳腺癌可塑性和药物治疗抵抗中的作用

N4-乙酰胞苷修饰的基本特征及其在肿瘤进展和治疗中的作用

RNA修饰相互作用的分子机制及其在肿瘤诊疗中的作用

CircABCA1 promotes ccRCC by reprogramming cholesterol metabolism and facilitating M2 macrophage polarization through IGF2BP3-mediated stabilization of SCARB1 mRNA

FNDC3B promotes gastric cancer metastasis via interacting with FAM83H and preventing its proteasomal degradation

Targeted delivery of circPDHK1 siRNA via aptamer functionalized lipid nanoparticles inhibits ccRCC growth and migration.

Circ-0007766作为miR-1972海绵调控HER2表达促进乳腺癌细胞迁移和侵袭

血清lncRNA T342620联合AFP对肝癌的诊断价值

RNA-binding protein IGF2BP2 suppresses metastasis of clear cell renal cell carcinoma by enhancing CKB mRNA stability and expression

Identification of Plasma hsa_circ_0001230 and hsa_circ_0023879 as Potential Novel Biomarkers for Focal Segmental Glomerulosclerosis and circRNA-miRNA-mRNA Network Analysis

Emerging roles of circular RNAs in tumorigenesis, progression, and treatment of gastric cancer

A novel protein FNDC3B-267aa encoded by circ0003692 inhibits gastric cancer metastasis via promoting proteasomal degradation of c-Myc

Construction of dual functional CuAl-LDHs nanocomposite loaded with IGF2BP3 siRNA for enhanced therapy of gastric cancer

A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway

PTBP1 knockdown impairs autophagy flux and inhibits gastric cancer progression through TXNIP-mediated oxidative stress

RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA

CircNFATC3 promotes the proliferation of gastric cancer through binding to IGF2BP3 and restricting its ubiquitination to enhance CCND1 mRNA stability

Circ-0003910在HER2阳性乳腺癌中的表达、定位、生物学作用及蛋白质组学研究

CBL通过泛素化降解NCK2抑制乳腺癌细胞的增殖和侵袭

基于CRISPR/Cas13a技术检测肿瘤驱动基因TP53 R248W的研究

乳腺癌组织miR-381和跨膜蛋白16A表达与临床病理特征及预后的关系

Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA

CircARID1A binds to IGF2BP3 in gastric cancer and promotes cancer proliferation by forming a circARID1A-IGF2BP3-SLC7A5 RNA–protein ternary complex

NR2F6在肿瘤中的研究进展

锌指蛋白家族的转录调控模式及其对肿瘤细胞发展进程的影响

Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL

研究生肿瘤分子生物学实验课程的改革

乳腺癌组织CBL-B蛋白表达与生物学行为和预后关系

立足交叉学科特色推进医学研究生肿瘤分子生物学课程的改革

Casitas B系淋巴瘤原癌基因在乳腺癌组织中的表达水平及其临床预后分析

CBLC在各分型分期乳腺癌中的表达差异及预后分析

miR-21a in exosomes from Lewis lung carcinoma cells accelerates tumor growth through targeting PDCD4 to enhance expansion of myeloid-derived suppressor cells

MiR-30a suppresses metastasis of gastric adenocarcinoma via targeting FAPα

Identification of plasma miR-106a-5p and miR-30a-5p as potential biomarkers for mesangial proliferative glomerulonephritis

稳定表达人源GRM4基因的乳腺癌细胞株的筛选及鉴定

CRISPR/Cas9文库筛选技术的发展及在肿瘤研究中的应用

Plasma circular RNA panel acts as a novel diagnostic biomarker for colorectal cancer

GRM4正向别构调节剂抑制乳腺癌细胞的增殖并促进细胞凋亡

Luminal亚型乳腺癌细胞与正常乳腺细胞的circRNA表达谱差异分析

稳定表达GRIK3乳腺癌MDA-MB-231细胞株的筛选及鉴定

翻译调控肿瘤蛋白的结构、功能以及在肿瘤发展中的作用

长非编码RNA在基因调控和肿瘤形成中的作用

RNAi基因沉默对消化系统肿瘤化疗敏感性的影响

miRNA对T细胞分化与功能的调节作用

miR-25在人胃癌组织中的表达分析及其靶基因TOB1的鉴定

幽门螺杆菌感染细胞模型的建立及感染相关microRNAs的筛选鉴定

microRNA在胃肠道肿瘤中的研究进展

miRNA在细胞因子表达调控中的作用

Mirtron——miRNA合成的新途径

炎症与肿瘤的关系研究进展

会议论文

MicroRNA-141通过靶向PDZ结合功能域转录共活化因子-TAZ抑制胃癌肿瘤生长代谢

预印本

Lung Tumour Cell-derived Exosomes Promote the Expansion of MDSC Through miR-21a/PDCD4/IL-6/STAT3 Pathway

研究方向