孙冰

2025

Does living alone exacerbate depression in older adults?

Frontiers In Psychology，Vol. 16

DOI

2025

临床中药学课程思政教学探索与实践

《济宁医学院学报》

2023

农村订单定向省属公费临床医学生自主学习能力现状及影响因素调查分析

《中国高等医学教育》

2022

中西医比较史课程的实践与探索

《济宁医学院学报》

2021

孙冰教授治疗多囊卵巢综合征不孕经验及验案举隅

《济宁医学院学报》

2021

李东垣重胃思想探析

《济宁医学院学报》

2021

Lactate anions participate in T cell cytokine production and function

Science China Life Sciences

DOI

2021

Targeting lysophospholipid acid receptor 1 and ROCK kinases promotes antiviral innate immunity

Science Advances

DOI

2021

Allergen protease-induced Gsdmd p40 controls IL-33 secretion

DOI

2021

Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants

Genome Medicine

DOI

2021

Cancer metabolism and tumor microenvironment: fostering each other?

Science China Life Sciences

DOI

2021

Novel neutralization mechanism of a human antibody with pan-coronavirus reactivity

DOI

2020

矮小症儿童和青少年血尿酸与丙氨酸转氨酶的相关性

《济宁医学院学报》

2020

医学继续教育绩效管理模块化模式实践

《临床医学研究与实践》

DOI

2020

中医经典课程“《伤寒论》选读”思政教学切入点探讨

《医学教育研究与实践》

DOI

2020

Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies

Cellular & Molecular Immunology

DOI

2020

Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients

Cellular & Molecular Immunology

DOI

2020

Protective humoral immunity in SARS-CoV-2 infected pediatric patients

Cellular & Molecular Immunology

DOI

2020

ECM1 is an essential factor for the determination of M1 macrophage polarization in IBD in response to LPS stimulation

Proceedings of the National Academy of Sciences of the United States of America

DOI

2020

TRIM34 attenuates colon inflammation and tumorigenesis by sustaining barrier integrity

Cellular & Molecular Immunology

DOI

2020

Author Correction: Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment

Nature Immunology

DOI

2020

Junctional and somatic hypermutation-induced CX4C motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing antibody

Cellular & Molecular Immunology

DOI

2020

Correction: β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes

Journal of Immunology

DOI

2019

基于云班课的PBL教学模式在临床见习中的应用

《医学教育研究与实践》

2019

《脉经》与“儒医”文化刍议

《医学与哲学》

2019

ECM1 Prevents Activation of Transforming Growth Factor beta, Hepatic Stellate Cells, and Fibrogenesis in Mice.

Gastroenterology

DOI

2019

ECM1 is a gatekeeper that restrains TGF-β activation to maintain liver homeostasis and prevent fibrogenesis

Zeitschrift für Gastroenterologie - German Journal of Gastroenterology

DOI

2019

NME4 regulates TLR3 activation and type I IFN production through autophagy-dependent TRAF6 degradation

Journal of Immunology

DOI

2019

ECM1 stabilizes matrix deposited latent TGF-β to maintain liver homeostasis and prevent fibrogenesis

Zeitschrift für Gastroenterologie - German Journal of Gastroenterology

DOI

2019

Gasdermin D Drives the Nonexosomal Secretion of Galectin-3, an Insulin Signal Antagonist

Journal of Immunology

DOI

2019

Hyperactivation of the NLRP3 inflammasome protects mice against influenza A virus infection via IL-1β mediated neutrophil recruitment.

Cytokine

DOI

2019

Advances in the regulation of T helper cell differentiation in asthma and lung cancer

DOI

2019

The function and potential drug targets of tumour-associated Tregs for cancer immunotherapy

Science China Life Sciences

DOI

2018

基于课程整合的小组讨论式教学应用体会

《中国高等医学教育》

2018

科学搭建医院绩效评价体系

《中国卫生》

2018

Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production

Proceedings of the National Academy of Sciences of the United States of America

DOI

2018

Modeling endophilin-mediated Aβ disposal in glioma cells.

Biochimica et biophysica acta. Molecular cell research

DOI

2018

Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation

Journal of Experimental Medicine

DOI

2018

Antiviral effects of ferric ammonium citrate

Cell Discovery

DOI

2017

艾灸对脑缺血-再灌注损伤大鼠MMP-9表达的影响

《济宁医学院学报》

2017

西医院校小班制中医学PBL教学实践与探索

《中国医药科学》

2017

师生角色互换联合PBL教学在中医课程整合中的应用

《中国高等医学教育》

2017

西医院校中医经典诵读大赛活动初探及思考

《中国高等医学教育》

2017

The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination

Journal of Experimental Medicine

DOI

2017

Interferons command Trim22 to fight against viruses

Cellular &Molecular Immunology

DOI

2017

Activation by Modulating Reactive Oxygen Domain-Containing 3 Inflammasome Regulates NLR Family, Pyrin Tripartite-Motif Protein 30 Negatively

2016

Novel function of Extracellular matrix protein 1 in suppressing Th17 cell development in experimental autoimmune encephalomyelitis

Journal of Immunology

DOI

2016

TET3 Inhibits Type I IFN Production Independent of DNA Demethylation.

Cell Reports

DOI

2016

Extra-cellular Matrix protein 1 (ECM1) Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) through Inhibition of MMP9 Activity

Journal of Immunology

DOI

2016

IFN-λ4 desensitizes the response to IFN-α treatment in chronic hepatitis C through long-term induction of USP18.

Journal of General Virology

DOI

2016

Sustained viral response and treatment‐induced cytopenia correlate with SLCs and KLF12 genotypes in interferon/ribavirin‐treated Chinese chronic hepatitis C patients

Journal of Gastroenterology and Hepatology

DOI

2016

IFN‐λ4はUSP18の長期誘導を通して慢性C型肝炎におけるIFN‐α治療への応答を脱感作する

2016

Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses

Nature Communications

DOI

2016

IFNL4 ss469415590 polymorphism contributes to treatment decisions in patients with chronic hepatitis C virus genotype 1b, but not 2a, infection.

Infection, Genetics and Evolution

DOI

2015

康复治疗学专业本科培养方案和课程设置探讨

《医学教育研究与实践》

2015

Casein Kinase II Controls TBK1/IRF3 Activation in IFN Response against Viral Infection

Journal of Immunology

DOI

2015

A Vero-cell-adapted vaccine donor strain of influenza A virus generated by serial passages.

Vaccine

DOI

2015

Cross-protection against influenza virus infection by intranasal administration of nucleoprotein-based vaccine with compound 48/80 adjuvant

Human Vaccines & Immunotherapeutics

DOI

2015

Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes

Journal of Immunology

DOI

2015

Replication Inhibition of Hepatitis B Virus and Hepatitis C Virus in Co-Infected Patients in Chinese Population

PLoS ONE

DOI

2015

CD24 Ala57Val polymorphism is associated with spontaneous viral clearance in the HCV‐infected Chinese population

Liver international (Print)

DOI

2015

Use of parenteral caffeinum natrio-benzoicum: an underestimated risk factor for HCV transmission in China

BMC Public Health

DOI

2015

The ns12.9 Accessory Protein of Human Coronavirus OC43 Is a Viroporin Involved in Virion Morphogenesis and Pathogenesis

Journal of Virology

DOI

2015

Extracellular matrix protein 1 plays a critical role in driving Th2 cell migration and controlling Th17 cell differentiation (IRC7P.434)

Journal of Immunology

DOI

2015

β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes

Journal of Immunology

DOI

2015

Interferon alpha (IFNα)-induced TRIM22 interrupts HCV replication by ubiquitinating NS5A

Cellular & Molecular Immunology

DOI

2015

TRIM35 negatively regulates TLR7‐ and TLR9‐mediated type I interferon production by targeting IRF7

FEBS Letters

DOI

2015

A single NS2 mutation of K86R promotes PR8 vaccine donor virus growth in Vero cells.

Virology

DOI

2015

TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING

PLoS Pathogens

DOI

2014

TH1/TH2 cell differentiation and molecular signals.

Advances in Experimental Medicine and Biology

DOI

2014

Differential IL‐10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction

European Journal of Immunology

DOI

2014

Infection of influenza virus neuraminidase-vaccinated mice with homologous influenza virus leads to strong protection against heterologous influenza viruses.

Journal of General Virology

DOI

2014

Human NLRP3 inflammasome senses multiple types of bacterial RNAs

Proceedings of the National Academy of Sciences of the United States of America

DOI

2014

Genistein as Antiviral Drug against HIV Ion Channel

Planta Medica

DOI

2014

Erratum to: Th1/Th2 Cell Differentiation and Molecular Signals.

Advances in Experimental Medicine and Biology

DOI

2014

Acapsular Cryptococcus neoformans activates the NLRP3 inflammasome.

Microbes and infection

DOI

2014

Immunogenicity of a monovalent 2009 influenza A (H1N1) vaccine in infants: randomized, observer-masked, single-center clinical study

SpringerPlus

DOI

2014

T Helper Cell Differentiation and Their Function

Advances in Experimental Medicine and Biology

DOI

2014

Corrigendum to “Novel sinomenine derivative 1032 improves immune suppression in experimental autoimmune encephalomyelitis” [Biochem. Biophys. Res. Commun. 391 (2010) 1093–1098]

DOI

2014

Overview of orchestration of CD4+ T cell subsets in immune responses.

Advances in Experimental Medicine and Biology

DOI

2014

The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus.

Journal of General Virology

DOI

2014

Th1/Th2 cell's function in immune system.

Advances in Experimental Medicine and Biology

DOI

2014

Long-Term Effect on Natural Killer Cells by Interferon-α Therapy on the Outcomes of HCV Infection

Journal of Interferon and Cytokine Research

DOI

2014

Kaempferol Derivatives as Antiviral Drugs against the 3a Channel Protein of Coronavirus

Planta Medica

DOI

2014

Novel function of ECM1 on inhibiting Th17 differentiation and infiltration in EAE development (BA13P.116)

Journal of Immunology

DOI

2014

Sumoylation of Influenza A Virus Nucleoprotein Is Essential for Intracellular Trafficking and Virus Growth

Journal of Virology

DOI

2013

糖尿病周围神经病变中医病机探讨

《济宁医学院学报》

2013

Cellular localization of NLRP3 inflammasome

Protein & Cell

DOI

2013

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

Cell Research

DOI

2013

Viral and Host Factors Required for Avian H5N1 Influenza A Virus Replication in Mammalian Cells

Viruses

DOI

2013

Novel Function of Trim44 Promotes an Antiviral Response by Stabilizing VISA

Journal of Immunology

DOI

2013

Negative Regulation of Interferon-induced Transmembrane Protein 3 by SET7-mediated Lysine Monomethylation*

Journal of Biological Chemistry

DOI

2013

The ORF4a protein of human coronavirus 229E functions as a viroporin that regulates viral production

Biochimica et Biophysica Acta

DOI

2013

Negative regulation of NLRP3 inflammasome signaling

Protein & Cell

DOI

2013

Negative Regulation of Nmi on Virus-Triggered Type I IFN Production by Targeting IRF7

Journal of Immunology

DOI

2013

Trim21: a novel negative regulator in DNA sensor signaling

Cellular & Molecular Immunology

DOI

2013

Unusual architecture of the p7 channel from hepatitis C virus

Nature

DOI

2012

单臂外固定器和组合式外固定器治疗小儿胫骨骨折临床疗效比较(附78例报告)

《山东医药》

2012

PBL教学法在小儿内分泌临床见习中的应用

《现代医药卫生》

2012

PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection

Virology Journal

DOI

2012

IL28B Genetic Variation Is Associated with Spontaneous Clearance of Hepatitis C Virus, Treatment Response, Serum IL-28B Levels in Chinese Population

PLoS ONE

DOI

2012

Coronaviral Ion Channels as Target for Chinese Herbal Medicine

DOI

2012

Fully human broadly neutralizing monoclonal antibodies against influenza A viruses generated from the memory B cells of a 2009 pandemic H1N1 influenza vaccine recipient

Virology

DOI

2012

PEDV ORF3 encodes an ion channel protein and regulates virus production

FEBS Letters

DOI

2012

Amino acids 473V and 598P of PB1 from an avian-origin influenza A virus contribute to polymerase activity, especially in mammalian cells.

Journal of General Virology

DOI

2012

Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein

Virology Journal

DOI

2012

Guanylate binding protein (GBP) 4 negatively regulates virus induced type I interferon and antiviral response by targeting interferon regulatory factor (IRF) 7 (168.30)

Journal of Immunology

DOI

2012

The long-term immunogenicity of an inactivated split-virion 2009 pandemic influenza A H1N1 vaccine: Randomized, observer-masked, single-center clinical study.

Results in Immunology

DOI

2011

基于数据库的脏腑病证平性药用药规律研究

《济宁医学院学报》

2011

Broad Humoral and Cellular Immunity Elicited by a Bivalent DNA Vaccine Encoding HA and NP Genes from an H5N1 Virus

Viral immunology

DOI

2011

DIDS blocks a chloride-dependent current that is mediated by the 2B protein of enterovirus 71

Cell Research

DOI

2011

ECM1 controls TH2 cell egress from lymph nodes through re-expression of S1P1

Nature Immunology

DOI

2011

High efficient method for obtaining antigen-specific B cells rapidly

2011

Emodin inhibits current through SARS-associated coronavirus 3a protein

Antiviral Research

DOI

2011

A detective monoclonal antibody recognized conserved epitope of hemagglutinin from H5N1 influenza virus

DOI

2011

Current understanding of Th2 cell differentiation and function

Protein & Cell

DOI

2011

Guanylate Binding Protein 4 Negatively Regulates Virus-Induced Type I IFN and Antiviral Response by Targeting IFN Regulatory Factor 7

Journal of Immunology

DOI

2011

Regulatory Factor 7 Antiviral Response by Targeting IFN Regulates Virus-Induced Type I IFN and Guanylate Binding Protein 4 Negatively

2010

还原型谷胱甘肽及厄贝沙坦对糖尿病肾病氧化应激的影响

《山东医药》

2010

PBL教学方法在《中医内科学》教学中的应用

《中国中医药现代远程教育》

2010

In Vivo Disruption of TGF-β Signaling by Smad7 in Airway Epithelium Alleviates Allergic Asthma but Aggravates Lung Carcinogenesis in Mouse

PLoS ONE

DOI

2010

The progress on differentiation and function of Th17 Cells

2010

Dec2 regulates initial TH2 lineage commitment (99.12)

Journal of Immunology

DOI

2010

Modification of Nonstructural Protein 1 of Influenza A Virus by SUMO1

Journal of Virology

DOI

2010

Influenza A Virus Replication Induces Cell Cycle Arrest in G0/G1 Phase

Journal of Virology

DOI

2010

Immune Protection Induced on Day 10 Following Administration of the 2009 A/H1N1 Pandemic Influenza Vaccine

PLoS ONE

DOI

2010

Novel sinomenine derivative 1032 improves immune suppression in experimental autoimmune encephalomyelitis.

Biochemical and Biophysical Research Communications - BBRC

DOI

2010

Viral proteins function as ion channels

Biochimica et Biophysica Acta

DOI

2010

This information is current as Production by Modulating Reactive Oxygen Species Regulates NLRP 3 Inflammasome Activation Tripartite-Motif Protein 30 Negatively and

2010

Development of retinol-binding protein 4 immunocolloidal gold fast test strip using high-sensitivity monoclonal antibodies generated by DNA immunization.

Acta Biochimica et Biophysica Sinica

DOI

2010

Influenza Virus Non-Structural Protein 1 (NS1) Disrupts Interferon Signaling

PLoS ONE

DOI

2010

The progress on differentiation and function of T follicular helper cells

2009

早期糖尿病肾病研究现状

《山东医药》

2009

Negative regulation of Toll-like receptor signaling pathway.

Microbes and infection

DOI

2009

Dec2 Promotes Th2 Cell Differentiation by Enhancing IL-2R Signaling1

Journal of Immunology

DOI

2009

Novel function of perforin in negatively regulating CD4+ T cell activation by affecting calcium signaling

Cell Research

DOI

2009

Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment

Nature Immunology

DOI

2009

Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein

Virology

DOI

2009

SARS Accessory Proteins ORF3a and 9b and Their Functional Analysis

Molecular Biology of the SARS-Coronavirus

DOI

2009

Trichosanthin functions as Th2-type adjuvant in induction of allergic airway inflammation

Cell Research

DOI

2008

TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation

Nature Immunology

DOI

2008

Negative Regulation of Virus-triggered IFN-β Signaling Pathway by Alternative Splicing of TBK1*

Journal of Biological Chemistry

DOI

2007

Differential expression of neutrophilic granule proteins between Th1 and Th2 cells.

Acta Biochimica et Biophysica Sinica

DOI

2007

Monoclonal antibody against non-dominant epitopes of HBV e Ag was raised by antigen-antibody co-immunization.

Journal of Biotechnology

DOI

2006

中西药联合治疗排卵障碍性不孕的疗效观察

《济宁医学院学报》

2006

A novel NF-kappaB binding site controls human granzyme B gene transcription.

Journal of Immunology

2006

Experimental study on transplantation of mice islets to different sites of diabetic mice

2006

Novel Function of IFN-γ: Negative Regulation of Dendritic Cell Migration and T Cell Priming1

Journal of Immunology

DOI

2006

IL-12p40 is not required for islet allograft rejection

Acta Pharmacologica Sinica

DOI

2006

Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release

Proceedings of the National Academy of Sciences of the United States of America

DOI

2006

SARS coronavirus pharmaceutical target and application thereof

2006

Effect of Zishen Prescription on Learning and Memory Ability of AD Rats

2006

Identification of core functional region of murine IL-4 using peptide phage display and molecular modeling.

International Immunology

DOI

2005

组合外固定架治疗胫骨多段骨折9例

《山东医药》

2005

表达胶质细胞源性神经生长因子的骨髓基质干细胞的神经分化潜能

2005

Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential

FEBS Letters

DOI

2005

Antibodies in SARS research

2005

N protein of SARS-coronavirus

2005

Characterization and application of monoclonal antibodies against N protein of SARS-coronavirus

Biochemical and Biophysical Research Communications - BBRC

DOI

2005

Antibody responses to individual proteins of SARS coronavirus and their neutralization activities

Microbes and infection

DOI

2004

愈溃膜口宝含片治疗复发性溃疡80例疗效观察

《济宁医学院学报》

2004

自制愈溃膜、口宝含片治疗复发性口腔溃疡疗效观察

《山东医药》

2004

An experimental study on the effects of GDNF and TGF-β co-transfection gene therapy in a rat Parkinson's model

2004

The spike protein of severe acute respiratory syndrome (SARS) is cleaved in virus infected Vero-E6 cells

Cell Research

DOI

2004

GDNF、TGF-β1联合治疗帕金森病的实验研究

2004

Expression of intracellular domain of epidermal growth factor receptor and generation of its monoclonal antibody.

Cellular & Molecular Immunology

2004

Characterization of the 3a Protein of SARS-associated Coronavirus in Infected Vero E6 Cells and SARS Patients

Journal of Molecular Biology

DOI

2003

充血性心衰ACEI治疗后醛固酮逃逸与螺内脂治疗的预后

《广东医学》

2003

胰岛素抵抗血脂与老年2型糖尿病合并高血压的关系探讨

《济宁医学院学报》

2003

IFN-γ up-regulation of IL-12 beta 2 receptor is associated with experimental autoimmune uveitis susceptible B10.A mice, but not in EAU resistant BALB/c mice

DOI

2003

Pertussis Toxin Enhances Th1 Responses by Stimulation of Dendritic Cells 1

Journal of Immunology

DOI

2003

The suppressive effect of triptolide on experimental autoimmune uveoretinitis by down-regulating Th1-type response.

International Immunopharmacology

DOI

2003

Dopaminergic trophism after intrastriatal injection of lentivirus-transferred GDNF in Parkinson rat model.

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

2003

IRBP-specific Th1 cells from peripheral blood were predominant in the experimental autoimmune uveitis.

Biochemical and Biophysical Research Communications - BBRC

DOI

2003

Identification of an epitope of SARS-coronavirus nucleocapsid protein

Cell Research

DOI

2002

脑血治治疗高血压性脑出血46例临床观察

《山东医药》

2002

Identification of the amino acid residues in trichosanthin crucial for IgE response.

Biochemical and Biophysical Research Communications - BBRC

DOI

2001

Identification of epitopes of trichosanthin by phage peptide library.

Biochemical and Biophysical Research Communications - BBRC

DOI

2001

Roles of IL-4 and other factors in the trichosanthin-induced ovalbumin-specific IgE response.

Acta Pharmacologica Sinica

2001

Inhibition of Th1- and enhancement of Th2-initiating cytokines and chemokines in trichosanthin- treated macrophages.

Biochemical and Biophysical Research Communications - BBRC

DOI

2001

IMMUNE RESPONSES IN PREGNANT MOUSE UTERUS INDUCED BY A SPERM ANTIGEN SA-30

2001

白介素-4和其他因子在天花粉蛋白诱导的卵清白蛋白特异性IgE应答过程中的作用(英文)

2001

High IFN-α expression is associated with the induction of experimental autoimmune uveitis (EAU) in Fischer 344 rat

Cell Research

DOI

2001

Th1／Th2极化：实验性自身免疫性葡萄膜炎

1999

PSMA mimotope isolated from phage displayed peptide library can induce PSMA specific immune response

Cell Research

DOI

1998

硬膜外阻滞无痛分娩效果观察

《山东医药》

Research Article Factors Associated with Spontaneous Clearance of Hepatitis C Virus in Chinese Population