洪科苗｜浙江理工大学｜学者主页

2026

Rhodium-Catalyzed Formal C-H and X-H Insertion Reaction Involving an Exocyclic Vinylic Cation Intermediate.

Kemiao Hong, Sha-Sha Chen, Jing-Xian Li, Zhuo-Feng Ke, Xin-Fang Xu

Organic Letters

DOI

2025

Rh(I)-Catalyzed [4+2]-annulation of furan-fused cyclobutanones with alkynes and synthetic applications

Xin-Fang Xu, Lixin Qian, Jing-Jing Huang, Kemiao Hong, Xinyu Jiang, Mengting Liu, Chen Gang, D. Gryko

Organic Chemistry Frontiers

DOI

2024

Enantioselective Construction of Quaternary Stereocenters via A Chiral Spiro Phosphoric Acid-Assisted Formal Gold Carbene gem-Dialkylation Reaction.

Kewei Chen, Su Zhou, Chao Li, Shan-Liang Dong, Kemiao Hong, Xin-Fang Xu

Journal of the American Chemical Society

DOI

2024

Gold-Catalyzed Alkyne Oxidative Cyclization/Mannich-Type Addition Cascade Reaction of Ynamides with 1,3,5-Triazinanes.

Kewei Chen, Chao Li, Shan-Liang Dong, Kemiao Hong, Jing-Jing Huang, Xin-Fang Xu

Journal of Organic Chemistry

DOI

2024

Catalytic (4+2) Annulation via Regio- and Enantioselective Interception of in-situ Generated Alkylgold Intermediate.

M. Bao, Yi Zhou, Haoxuan Yuan, Guizhi Dong, Chao Li, Xiongda Xie, Kewei Chen, Kemiao Hong, Zhi-Xiang Yu, Xin-Fang Xu

Angewandte Chemie

DOI

2024

Catalytic [4+2]- and [4+4]-cycloaddition using furan-fused cyclobutanone as a privileged C4 synthon

Kemiao Hong, Mengting Liu, Lixin Qian, M. Bao, Gang Chen, Xinyu Jiang, Jing-Jing Huang, Xin-Fang Xu

Nature Communications

DOI

2024

Catalytic Asymmetric Difluoroalkylation Using In Situ Generated Difluoroenol Species as the Privileged Synthon

Xiongda Xie, Shan-Liang Dong, Kemiao Hong, Jing-Jing Huang, Xin-Fang Xu

Advancement of science

DOI

2024

Practical and modular cycloadditions of in-situ formed exocyclic vinylcarbenes

Cheng Zhang, Shan-Liang Dong, M. Dietl, M. Rudolph, Xin-Ke Zhang, Kemiao Hong, Wei Yi, A. Hashmi, Xin-Fang Xu

Chem Catalysis

DOI

2024

Enantioselective Assembly of Fully Substituted α‐Amino Allenoates Through a Mannich Addition and Stepwise [3,3]‐σ Rearrangement Sequence

Haoxuan Yuan, Yi Zhou, Xiongda Xie, M. Bao, Kewei Chen, Kemiao Hong, Zhi-Xiang Yu, Xin-Fang Xu

Advancement of science

DOI

2023

Construction of Chiral Quaternary Carbon Centers via Asymmetric Metal Carbene gem-Dialkylation.

Shan-Liang Dong, Kemiao Hong, Zhijing Zhang, Jing-Jing Huang, Xiongda Xie, Haoxuan Yuan, Wenhao Hu, Xin-Fang Xu

Angewandte Chemie

DOI

2023

Catalytic 4-exo-dig carbocyclization for the construction of furan-fused cyclobutanones and synthetic applications

Kemiao Hong, Yi Zhou, Haoxuan Yuan, Zhijing Zhang, Jing-Jing Huang, Shan-Liang Dong, Wen-Hao Hu, Zhi-Xiang Yu, Xin-Fang Xu

Nature Communications

DOI

2023

Regio- and diastereoselective construction of conjugate oxindole derivatives enabled by delayed acyl transfer of pyridinium ylides

Mengchu Zhang, Geng-Xin Liu, Tianyuan Zhang, Kemiao Hong, Xiangji Yang, H. Qiu, Wenhao Hu

Organic Chemistry Frontiers

DOI

2023

Utilization of Sulfoxonium Ylides and Anthranils in Transition Metal-Catalyzed C − H Activation/Annulation Reaction

Yogesh N Aher, Amit B. Pawar, V. G. Alfonso, M. Suero, M. Álvarez, Francisco Villalba, A. Lledós, A. Albéniz, T. R. Belderrain, P. Pérez, Long-Hay Au, N. P. van Leest, Kexin Yin, C. Che, M. Bevilacqua, Kevin Breitwieser, F. Dankert, B. Morgenstern, A. Biffis, Christian Hering-Junghansc, Dominik Munz, Nemrud Demirel, E. Meggers, Hoi-Min Jung, Dongwook Kim, Sukbok Chang, Christina Ng, Jesse Ling, S. D. de Wit, Zhi-Yuan He, Samuel M. van der Loo, T. Kwakkelstein, J. I. van der Vlugt, B. de Bruin, Kemiao Hong, Shan-Liang Dong, Su Zhou, Xin-Fang Xu, Tingjie You, Si-Hao Zeng, Jianqiang Fan, Liangliang Wu, Fangyuan Kang, Yun-Gen Liu, Rik Bennis

2023

Generation and Utility of Cyclic Dienyl Gold Carbene Intermediates

Cheng Zhang, Kemiao Hong, Shan-Liang Dong, Mengting Liu, M. Rudolph, M. Dietl, Jian Yin, A. Hashmi, Xin-Fang Xu

ACS Catalysis

DOI

2022

氮宾/炔烃复分解串联反应研究进展（英文）

洪科苗，黄晶晶，姚铭瀚，徐新芳

《有机化学》

2022

Chiral rhodium(II)-catalyzed asymmetric aldol-type interception of an oxonium ylide to assemble chiral 2,3-dihydropyrans

Ai-Min Xu, Xiaoyu Zhou, Rimei Zheng, Zhijing Zhang, Xinru Yin, Kemiao Hong, Zhuofeng Ke, Y. Qian, Wenhao Hu

Science China Chemistry

DOI

2022

Asymmetric Three-Component Reaction of Enynal with Alcohol and Imine as An Expeditious Track to Afford Chiral α-Furyl-β-amino Carboxylate Derivatives

Kemiao Hong, Jirong Shu, Shan-Liang Dong, Zhijing Zhang, Yi-Cheng He, Mengting Liu, Jing-Jing Huang, Wenhao Hu, Xin-Fang Xu

ACS Catalysis

DOI

2022

Diastereoselective aldol-type interception of phenolic oxonium ylides for the direct assembly of 2,2-disubstituted dihydrobenzofurans.

Kemiao Hong, Xiangji Yang, Zhijing Zhang, Xiongda Xie, Xin-Xin Lv, Xin-Fang Xu, Wenhao Hu

Organic and biomolecular chemistry

DOI

2022

Recent Advances in Nitrene/Alkyne Metathesis Cascade Reaction

Kemiao Hong, Jing-Jing Huang, Ming-Han Yao, Xin-Fang Xu

Youji huaxue

DOI

2022

Asymmetric Three-Component Reaction of Two Diazo Compounds and Hyrdroxylamine Derivatives for the Access to Chiral α-Alkoxy-β-amino-carboxylates

Xiang Yang, Kemiao Hong, Sujie Zhang, Zhijing Zhang, Su Zhou, Jing-Jing Huang, Xin-Fang Xu, Wenhao Hu

ACS Catalysis

DOI

2021

Enantioselective assembly of 3,3-disubstituted succinimides via three-component reaction of vinyl diazosuccinimides with alcohols and imines.

Haoxuan Yuan, Kemiao Hong, Xiang-Rong Liu, Y. Qian, Xin-Fang Xu, Wenhao Hu

Chemical Communications

DOI

2021

Highly diastereoselective synthesis of vicinal diamines via a Rh-catalyzed three-component reaction of diazo compounds with diarylmethanimines and ketimines

Kai Zhou, M. Bao, Hong-Kai Sha, Guizhi Dong, Kemiao Hong, Xin-Fang Xu, Wenhao Hu

Organic Chemistry Frontiers

DOI

2021

Enantioselective Intermolecular Mannich-Type Interception of Phenolic Oxonium Ylide for the Direct Assembly of Chiral 2,2-Disubstituted Dihydrobenzofurans

Kemiao Hong, Shan-Liang Dong, Xin-Xin Xu, Zhijing Zhang, Tao-Da Shi, Haoxuan Yuan, Xin-Fang Xu, Wenhao Hu

DOI

2020

Rh-Catalyzed nitrene alkyne metathesis/formal C–N bond insertion cascade: synthesis of 3-iminoindolines

Kemiao Hong, Su Zhou, Wenhao Hu, Xin-Fang Xu

DOI

2020

Gold(I)-catalyzed intramolecular cyclization/intermolecular cycloaddition cascade as a fast track to polycarbocycles and mechanistic insights

Cheng Zhang, Kemiao Hong, Chao Pei, Su Zhou, Wenhao Hu, A. Hashmi, Xin-Fang Xu

Nature Communications

DOI

2020

Blue Light-Promoted Formal [4+1]-Annulation of Diazoacetates with o-Aminoacetophenones: Synthesis of Polysubstituted Indolines and Computational Study.

Jinzhou Chen, Shu-Hao Liu, Xin-Xin Lv, Kemiao Hong, Jinping Lei, Xin-Fang Xu, Wenhao Hu

Journal of Organic Chemistry

DOI

2020

Desaturation via Redox-Neutral Hydrogen Transfer Process: Synthesis of 2-Allyl Anilines, Mechanism and Applications

Yang Zheng, P. Dai, Dafang Gao, Kemiao Hong, Luyao Kou, Shan-Liang Dong, Jun-Die Hu, Lihua Qiu, Wenhao Hu, Xiao-Guang Bao, Xin-Fang Xu

iScience

DOI

2019

Gold(I)-Catalyzed Aromatization: Expeditious Synthesis of Polyfunctionalized Naphthalenes

Cheng Zhang, Kemiao Hong, Shan-Liang Dong, Chao Pei, Xiao-Lu Zhang, Ciwang He, Wenhao Hu, Xin-Fang Xu

iScience

DOI

2019

Rhodium-Catalyzed Nitrene/Alkyne Metathesis: An Enantioselective Process for the Synthesis of N-Heterocycles.

Kemiao Hong, H. Su, Chao Pei, Xin-Xin Lv, Wenhao Hu, Lihua Qiu, Xin-Fang Xu

Organic Letters

DOI

2018

Copper- or Thermally Induced Divergent Outcomes: Synthesis of 4-Methyl 2H-Chromenes and Spiro-4H-Pyrazoles.

Yang Zheng, Lihua Qiu, Kemiao Hong, Shan-Liang Dong, Xin-Fang Xu

Chemistry

DOI

2018

Frontispiece: Copper‐ or Thermally Induced Divergent Outcomes: Synthesis of 4‐Methyl 2H‐Chromenes and Spiro‐4H‐Pyrazoles

Yang Zheng, Lihua Qiu, Kemiao Hong, Shan-Liang Dong, Xin-Fang Xu

DOI

洪科苗

精选作品

期刊论文

Rhodium-Catalyzed Formal C-H and X-H Insertion Reaction Involving an Exocyclic Vinylic Cation Intermediate.

Rh(I)-Catalyzed [4+2]-annulation of furan-fused cyclobutanones with alkynes and synthetic applications

Enantioselective Construction of Quaternary Stereocenters via A Chiral Spiro Phosphoric Acid-Assisted Formal Gold Carbene gem-Dialkylation Reaction.

Gold-Catalyzed Alkyne Oxidative Cyclization/Mannich-Type Addition Cascade Reaction of Ynamides with 1,3,5-Triazinanes.

Catalytic (4+2) Annulation via Regio- and Enantioselective Interception of in-situ Generated Alkylgold Intermediate.

Catalytic [4+2]- and [4+4]-cycloaddition using furan-fused cyclobutanone as a privileged C4 synthon

Catalytic Asymmetric Difluoroalkylation Using In Situ Generated Difluoroenol Species as the Privileged Synthon

Practical and modular cycloadditions of in-situ formed exocyclic vinylcarbenes

Enantioselective Assembly of Fully Substituted α‐Amino Allenoates Through a Mannich Addition and Stepwise [3,3]‐σ Rearrangement Sequence

Construction of Chiral Quaternary Carbon Centers via Asymmetric Metal Carbene gem-Dialkylation.

Catalytic 4-exo-dig carbocyclization for the construction of furan-fused cyclobutanones and synthetic applications

Regio- and diastereoselective construction of conjugate oxindole derivatives enabled by delayed acyl transfer of pyridinium ylides

Utilization of Sulfoxonium Ylides and Anthranils in Transition Metal-Catalyzed C − H Activation/Annulation Reaction

Generation and Utility of Cyclic Dienyl Gold Carbene Intermediates

氮宾/炔烃复分解串联反应研究进展（英文）

Chiral rhodium(II)-catalyzed asymmetric aldol-type interception of an oxonium ylide to assemble chiral 2,3-dihydropyrans

Asymmetric Three-Component Reaction of Enynal with Alcohol and Imine as An Expeditious Track to Afford Chiral α-Furyl-β-amino Carboxylate Derivatives

Diastereoselective aldol-type interception of phenolic oxonium ylides for the direct assembly of 2,2-disubstituted dihydrobenzofurans.

Recent Advances in Nitrene/Alkyne Metathesis Cascade Reaction

Asymmetric Three-Component Reaction of Two Diazo Compounds and Hyrdroxylamine Derivatives for the Access to Chiral α-Alkoxy-β-amino-carboxylates

Enantioselective assembly of 3,3-disubstituted succinimides via three-component reaction of vinyl diazosuccinimides with alcohols and imines.

Highly diastereoselective synthesis of vicinal diamines via a Rh-catalyzed three-component reaction of diazo compounds with diarylmethanimines and ketimines

Enantioselective Intermolecular Mannich-Type Interception of Phenolic Oxonium Ylide for the Direct Assembly of Chiral 2,2-Disubstituted Dihydrobenzofurans

Rh-Catalyzed nitrene alkyne metathesis/formal C–N bond insertion cascade: synthesis of 3-iminoindolines

Gold(I)-catalyzed intramolecular cyclization/intermolecular cycloaddition cascade as a fast track to polycarbocycles and mechanistic insights

Blue Light-Promoted Formal [4+1]-Annulation of Diazoacetates with o-Aminoacetophenones: Synthesis of Polysubstituted Indolines and Computational Study.

Desaturation via Redox-Neutral Hydrogen Transfer Process: Synthesis of 2-Allyl Anilines, Mechanism and Applications

Gold(I)-Catalyzed Aromatization: Expeditious Synthesis of Polyfunctionalized Naphthalenes

Rhodium-Catalyzed Nitrene/Alkyne Metathesis: An Enantioselective Process for the Synthesis of N-Heterocycles.

Copper- or Thermally Induced Divergent Outcomes: Synthesis of 4-Methyl 2H-Chromenes and Spiro-4H-Pyrazoles.

Frontispiece: Copper‐ or Thermally Induced Divergent Outcomes: Synthesis of 4‐Methyl 2H‐Chromenes and Spiro‐4H‐Pyrazoles

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