黄震｜湖北大学｜学者主页

百晓学者学者目录

精选作品

期刊论文

2026

硒原子锁缓释核苷药物分子研究

秦童，罗丹妍，王绍昕，黄震

《中国药学杂志》

2026

Synthesis and RNA Transcription of Colored 4-Selenouridine Triphosphate with Atom Mutagenesis

Dan Liu, Huiyan Sun, Sibo Jiang, Jin Pei, Zhen Huang

RNA

DOI

2026

Enhancing DNAzyme Silencing via Phosphorothiolation to Reduce the Mg 2+ ‐Dependence

Zhongchun Zhou, Wen Sun, Xiang Gu, Zhen Huang

Biotechnology Journal

DOI

2025

Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD+

Chulei Cao, Jie Yang, Weizhen Zhang, Jiaqin Chen, Yanqing Gao, Yuqi Yao, Yixi Zhang, Huili Li, Linxi Li, Zhaorong Luo, Chenxi Wang, Guangli Tang, Cui Ruixue, Hehua Liu, Qiyao Wang, Zhen Huang, Jinbiao Ma, Jianhua Gan

Nature Communications

DOI

2025

Probing and Enhancing DNA Ligase Specificity via Se‐Atom‐Mutagenesis of ATP for Accurate Gene Synthesis and Detection

Dejin Xu, Bei Hu, Xiaoling Ding, Tong Qin, Ting Li, Jiaxin Li, Danyan Luo, Lu Chen, Yunfan Xu, Jun Zhang, Han Chang Kang, Yang Zhang, Zhen Huang

Angewandte Chemie

DOI

2025

Selenium-derivatized Nucleic Acids for Phasing, Crystal Growth, Structure Determination and Beyond

Zhen Huang, Hehua Liu, Jianhua Gan

Structural Dynamics

DOI

2025

Crystal Engineering of Nucleic Acid Macro-molecules using Selenium Atoms

Zhen Huang, Hehua Liu, Jianhua Gan

Structural Dynamics

DOI

2025

One-pot ligation of multiple mRNA fragments on dsDNA splint advancing regional modification and translation

Yunfan Xu, Shuopeng Qi, Gongrui Zhang, Dan Liu, Dejin Xu, Tong Qin, Qin Cheng, Han Chang Kang, Bei Hu, Zhen Huang

Nucleic Acids Research

DOI

2021

磷硫代siRNA的YAP基因沉默活性研究

唐硕，黄震

《四川大学学报(自然科学版)》

DOI

2020

磷硫代siRNA的抗肿瘤基因沉默活性研究

王均，黄震

《四川大学学报(自然科学版)》

2019

上市核酸药物的疗效分析和研究进展

王均，王兰，吕家臻，黄震

《中国新药杂志》

研究方向

mRNA/siRNA/反义核酸药物结构化学生物学病原体与癌症核酸追踪检测及早期诊断小分子创新药与抗癌化学生物学硒核酸生物信息学与营养健康

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