百晓学者学者目录

崔闻

副教授、教授，重庆医科大学

精选作品

期刊论文

2025

Substrate recognition and cleavage mechanism of the monkeypox virus core protease

Yan Gao, Xiong Xie, Xiaoyu Zhang, Junyuan Cao, Weiqi Lan, Tian You, Dongxu Li, Xuxue Dong, Wenhao Dai, Yingchun Xiang, Shulei Hu, Weijuan Shang, Botao Wu, Yumin Zhang, Jin Xu, Xiaoce Liu, Haofeng Wang, Wanlong Hu, Mingjing Zhang, Yinkai Duan, Wen Cui, Hao Zhou, Shengjiang Mao, Handi Jia, Zhanqi Sun, Menghan Jia, Yue Yin, Henry C. Nguyen, Kailin Yang, Bei Yang, Xiuna Yang, Xiaoyun Ji, Gengfu Xiao, Wei Wang, Leike Zhang, Zihe Rao, Hong Shu Liu, Haitao Yang

Nature

DOI

2025

High-Throughput Discovery of Inhibitors Targeting Monkeypox Virus H1 Phosphatase

Chengcheng Tao, Mailikezhati Alifu, Haojun Huang, Zhi Luo, Yaxian Li, Xuecen Guan, Mengmeng Liu, Junchi Hu, Wen Cui, Wei J. Wang

Viruses

DOI

2025

Structural and mechanistic insight into the phosphorylation reaction catalyzed by mpox virus thymidine kinase

Tenan Zhang, Xiang Chen, Chengcheng Tao, Haojun Huang, Zhi Luo, Mengmeng Liu, Wen Cui, Wei Wang

Antiviral Research

DOI

2024

Structural review of SARS-CoV-2 antiviral targets

Wen Cui, Yinkai Duan, Yan Gao, Wei Wang, Haitao Yang

Structure

DOI

2024

Determinants of the interaction between the 5′-leader of HIV-1 genome and human lysyl-tRNA synthetase in reverse transcription primer release process

Yong Liu, Yong Liu, Zhi Luo, Xiang 'Anthony' Chen, Xin Thomas Yang, Qi Qi, Mailikezhati Alifu, Chengcheng Tao, Wen Cui, Mengmeng Liu, Wei Wang

Biochemical and Biophysical Research Communications

DOI

2023

Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors

Deping Wang, Rong Zhao, Hao-Feng Wang, Mei-Yue Wang, Wen-Shu Hu, Meng-Meng Lin, Wen Shu, Yaojun Sun, Ji‐Min Cao, Wen Cui, Xin Zhou

International Journal of Biological Macromolecules

DOI

2022

Crystal structure of monkeypox H1 phosphatase, an antiviral drug target

Wen Cui, Haojun Huang, Yinkai Duan, Zhi Luo, Haofeng Wang, Tenan Zhang, Henry C. Nguyen, Wei L. Shen, Dan Su, Xi Li, Xiaoyun Ji, Haitao Yang, Wei Wang

Protein & Cell

DOI

2022

Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue

Haofeng Wang, Yunjie Xiao, Xia Chen, Mengwen Zhang, Guangxin Sun, Feng Wang, Lin Wang, Hanxiao Zhang, Xiaoyu Zhang, Xin Yang, Wenling Li, Yi Wei, Deqiang Yao, Bing Zhang, Jun Li, Wen Cui, Fenghua Wang, Cheng Chen, Wei L. Shen, Dan Su, Fang Bai, Jinhai Huang, Sheng Ye, Lei Zhang, Xiaoyun Ji, Wei Wang, Zefang Wang, Mark Hochstrasser, Haitao Yang

Nature Communications

DOI

2022

Distinct Gag interaction properties of HIV-1 RNA 5′ leader conformers reveal a mechanism for dimeric genome selection

Xin Thomas Yang, Yong Liu, Wen Cui, Mengmeng Liu, Wei Wang

RNA

DOI

2022

Toward an accurate mechanistic understanding of Wolbachia‐ induced cytoplasmic incompatibility

Wei Wang, Wen Cui, Haitao Yang

Environmental Microbiology

DOI

2022

Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design

Deping Wang, Mei-Yue Wang, Yongmei Li, Wen Shu, Wen Cui, Fangying Jiang, Xin Zhou, Wenming Wang, Ji‐Min Cao

Cell & Bioscience

DOI

2021

Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis

Mengmeng Lin, Wen Cui, Hongliang Tian, Yan Zhang, Chen Chen, Xiaoyun Yang, Heng Chi, Zhongyu Mu, Cheng Chen, Zefang Wang, Xiaoyun Ji, Haitao Yang, Zhi Lin

ACS Infectious Diseases

DOI

2021

Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors

Yunjie Xiao, Hongli Chen, Haofeng Wang, Mengwen Zhang, Xia Chen, Jason M. Berk, Lilin Zhang, Yi Wei, Wenling Li, Wen Cui, Fenghua Wang, Qianfan Wang, Can Cui, Ting Li, Cheng Chen, Sheng Ye, Lei Zhang, Xiaoyun Ji, Jinhai Huang, Wei Wang, Zefang Wang, Mark Hochstrasser, Haitao Yang

Proceedings of the National Academy of Sciences

DOI

2020

Recent Progress in the Drug Development Targeting SARS-CoV-2 Main Protease as Treatment for COVID-19

Wen Cui, Kailin Yang, Haitao Yang

Frontiers in Molecular Biosciences

DOI

2019

鸟苷酸结合蛋白二聚化激活的机制研究

崔闻

《天津大学》

2019

The crystal structure of main protease from mouse hepatitis virus A59 in complex with an inhibitor

Wen Cui, S. Cui, Cheng Chen, Xia Chen, Zefang Wang, Haitao Yang, Lei Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

2019

Corrigendum to “The crystal structure of main protease from mouse hepatitis virus A59 in complex with an inhibitor” [BBRC 511/4 (2019) 794–799]

Wen Cui, S. Cui, Cheng Chen, Xia Chen, Zefang Wang, Haitao Yang, Lei Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

研究方向

重要病原体的关键药物靶点的结构和功能

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