郑秋凌｜中国药科大学｜学者主页

2026

A Metabolomics-Based Strategy for Identifying Endogenous Inhibitors of IAPP Aggregation

Dandan Xia, Liubao Gu, Lei Yang, Jiaojiao Hu, Xiaowei Xu, Dechen Jiang, Qiuling Zheng, Bing Wan

Metabolites

2026

Cardiac α4β2 nicotinic receptors as a therapeutic target for fatal ventricular arrhythmias

Duanyang Xie, Wenjian Min, Guanghua Wang, Qicheng Zou, Qiuling Zheng, Z Chen, Beihua Shao, Peng Yang, Han Sun, Ke Xiong, Hongcheng Gu, Jiale Shi, Xiao Xu, Hongtao Xu, Yixin Yuan, Xuxia Zhao, Xiaofei Tao, Yuesheng Wang, Ying Liu, Nianguo Dong, Haiping Hao, Yi-Han Chen

European Heart Journal

精选作品

期刊论文

A Metabolomics-Based Strategy for Identifying Endogenous Inhibitors of IAPP Aggregation

Cardiac α4β2 nicotinic receptors as a therapeutic target for fatal ventricular arrhythmias

A Novel FXR-Targeted DUBTAC and Its Applications in Cholestasis Therapy

Integrated plasma and red blood cell membrane lipidomics analysis unveils novel biomarker panel for Alzheimer’s disease

Structural Optimization of Pyrazole Compounds as Hsp90 Regulators with Enhanced Antitumor Activity

Transient Cross-linking Mass Spectrometry: Taking Conformational Snapshots of Proteins

Methylcobalamin protects against liver failure via engaging gasdermin E

Unmodified methodologies in target discovery for small molecule drugs: A rising star

Selective Photoaffinity Probe for Monitoring Farnesoid X Receptor Expression in Cultured Cells

Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS

Evaluation of Untargeted Metabolomic Strategy for the Discovery of Biomarker of Breast Cancer

Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2

Boronic derivatization-based strategy for monoacylglycerol identification, isomer annotation and quantification

Drug target discovery by magnetic nanoparticles coupled mass spectrometry

Hydrogen selenide, a vital metabolite of sodium selenite, uncouples the sulfilimine bond and promotes the reversal of liver fibrosis

An improved detection and identification strategy for untargeted metabolomics based on UPLC-MS

Applications of Mass Spectrometry in the Onset of Amyloid Fibril Formation: Focus on the Analysis of Early-Stage Oligomers

Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis

脾氨肽口服冻干粉中活性多肽的分离及鉴定

Prediction of fibril formation by early-stage amyloid peptide aggregation

Boronic Derivatization of Monoacylglycerol and Monitoring in Biofluids

Ligand–protein target screening from cell matrices using reactive desorption electrospray ionization-mass spectrometry via a native-denatured exchange approach

Noncanonical farnesoid X receptor signaling inhibits apoptosis and impedes liver fibrosis

Probing specific ligand-protein interactions by native-denatured exchange mass spectrometry

会议论文

原态变性交换质谱表征蛋白配体相互作用

基于代谢-蛋白组学技术揭示小分子的作用靶标

原态-变性转换离子源进行蛋白-配体复合物的研究