刘祖国｜厦门大学｜学者主页

2026

眼周美容操作相关睑板腺疾病诊疗专家共识（2026）

邵毅，李正日，刘祖国，国际眼科协会，中国医药教育协会眼科影像与智能医疗分会，国际智能医学会眼科专业委员会

《国际眼科杂志》

2026

干眼是“打工人”的勋章

刘祖国，关文英

《大众医学》

2026

眼科手术表面麻醉剂应用专家共识

海峡两岸医药卫生交流协会眼科学专业委员会手术室麻醉学组，甘小亮，韩园，李晓峰，刘祖国，邵毅，张钦，归纯漪，刘颖，张海容

《眼科学报》

2026

The Hippo signaling pathway regulates corneal endothelial regeneration

Jingbin Zhuang, Yuli Guo, Haitao Zhang, Meiqin Zhong, Xu Hu, Lingyu Zhang, Jingwen Yu, Yuqian Wang, Shundong Cai, Huping Wu, Chengchao Chu, Hui He, Rongrong Zong, Weifu Huang, Andrew J. Quantock, Zuguo Liu, Jinghua Bu

The Ocular Surface

精选作品

期刊论文

眼周美容操作相关睑板腺疾病诊疗专家共识（2026）

干眼是“打工人”的勋章

眼科手术表面麻醉剂应用专家共识

The Hippo signaling pathway regulates corneal endothelial regeneration

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Targeted degradation of VEGFR2 via PROTAC encapsulated by cRGD-liposome reverses pathological corneal neovascularization

Lifitegrast ophthalmic solution 5% for the treatment of the signs and symptoms of dry eye disease: a review of clinical trials and real-world evidence

Adverse Drug Events Associated With Six Classes of Glaucoma Medications: A Retrospective Pharmacovigilance Study Using Real-World Data From The FAERS Database

TFOS DEWS III Management and Therapy Report.

A deep learning based system for detecting abnormalities in the lower eyelid of smartphone images

Advancing Ophthalmology With Large Language Models: Applications, Challenges, and Future Directions.

Topical Pharmacologic Treatments for Dry Eye Disease: A Systematic Review.

Prostaglandin F2α exacerbated dry eye by promoting lacrimal gland fibrosis progression through the activation of the RhoA/ROCKs signaling pathway

Ocular Surface Involvements in the Development of Sjögren's Syndrome–Associated Dry Eye in the IL14α Transgenic Mouse

L009 peptide as a novel antiangiogenic agent for corneal neovascularization via regulation of the TNFSF15-VEGF axis

Corrigendum to “Models for Meibomian gland dysfunction: In vivo and in vitro”, Review article [Ocul. Surf. 32 (2024) 154–165]

Assessment of the clonal growth potential of meibomian gland stem/progenitor cells via clonal analysis

Microbial influx during early postnatal life fortifies the ocular surface and guards against allergic eye disease in mice

A bioequivalent cornea cross-linking method using photo-initiators LAP and visible light

Retrospective cohort study of ocular adverse reactions to systemic drugs: insights from a multi-country spontaneous reporting database

Advances and challenges of targeted protein degradation in ophthalmology: Future directions and therapeutic potential

Drug-related visual blurring: findings from the U.S. Food and Drug Administration Adverse Event Reporting System database

Recent Achievements and Perspectives in Smart Nano-in-Micro Platforms for Ocular Disease Treatment

Topical delivery of cultivated limbal stem cells via porous photocurable hydrogel: A noninvasive, convenient, and efficient stem cells delivery strategy for limbal stem cell deficiency

Evaluation of Nano-Niclosamide in Killing Demodex folliculorum In Vitro and the Potential Application in Ocular Surface

Deep learning-based automatic image quality control system for anterior eye segment in slit lamp and smartphone

Disrupted Mitochondrial Dynamics Impair Corneal Epithelial Healing in Neurotrophic Keratopathy

Light-emitting diode-derived blue light overexposure accelerates corneal endothelial cell aging by inducing abnormal ROS accumulation

Current Pharmaceutical Therapies for Meibomian Gland Dysfunction: From Basic Research to Clinical Practice

Ursolic acid ameliorates ocular surface dysfunction in dry eye via targeting EGFR/RAS/RAF/MAP2K1/MAPK1 pathway

获得性免疫在干眼的启动与维持

Eye-redness grading system based on deep learning and smartphone images: Application and innovation of improved ConvNeXt model

In vitro killing effect of berberine and niclosamide on ocular Demodex folliculorum

Advances and prospects of multi-modal ophthalmic artificial intelligence based on deep learning: a review

Real-World Large Sample Assessment of Drug-related Dry Eye Risk: Based on the FDA Adverse Event Reporting System Database

Psychometric validation of the Chinese version of the dry eye-related quality-of-life score questionnaire

Alkali burn injury model of meibomian gland dysfunction in mice

Cell death pathways in dry eye disease: Insights into ocular surface inflammation

Models for Meibomian gland dysfunction: In vivo and in vitro

Advances in adhesive hydrogels applied for ophthalmology: An overview focused on the treatment

Drug-Related Keratitis: A Real-World FDA Adverse Event Reporting System Database Study

Effect of laughter exercise versus 0.1% sodium hyaluronic acid on ocular surface discomfort in dry eye disease: non-inferiority randomised controlled trial

Research progress of photo-crosslink hydrogels in ophthalmology: A comprehensive review focus on the applications

DEEPOREDNET: Contrastive Learning-Based Attention-Weighted Dual Channel Residual Network for Ocular Redness Assessment

Adverse events of topical ocular prostaglandin medications for glaucoma treatment: a pharmacovigilance study based on the FAERS database

Drug‐associated glaucoma: A real‐world study based on the Food and Drug Administration adverse event reporting system database

Multifaceted mitochondrial as a novel therapeutic target in dry eye: insights and interventions

Unleashing Novel Therapeutic Strategies for Dry Eye: Targeting ROS and the cGAS‐STING Signaling Pathway with Tetrahedral Framework Nucleic Acids

Bi-DenseNet: Automatic recognition of ocular surface disease using smartphone imaging

人工智能在眼前节疾病诊断中的应用指南(2023)

Limbal Stem Cell Dysfunction Induced by Severe Dry Eye via Activation of the p38 MAPK Signaling Pathway.

Transitory alkali exposure on meibomian gland orifices induces meibomian gland dysfunction.

AES-CSFS: an automatic evaluation system for corneal sodium fluorescein staining based on deep learning

A Fully Automatic Estimation of Tear Meniscus Height Using Artificial Intelligence

Accurate detection and grading of pterygium through smartphone by a fusion training model

Guidelines for the application of artificial intelligence in the diagnosis of anterior segment diseases (2023)

T-Cell Repertoire Analysis in the Conjunctiva of Murine Dry Eye Model

The cGAS-STING pathway-dependent sensing of mitochondrial DNA mediates ocular surface inflammation

Smart coating by thermo-sensitive Pluronic F-127 for enhanced corneal healing via delivery of biological macromolecule progranulin

Corneal stromal filler injection of gelatin-based photocurable hydrogels for maintaining the corneal thickness and reconstruction of corneal stroma

Decellularized squid mantle scaffolds as tissue‐engineered corneal stroma for promoting corneal regeneration

Highly effective corneal permeability of reactive oxygen species-responsive nano-formulation encapsulated cyclosporine a for dry eye management

A Rational Design of Metal–Organic Framework Nanozyme with High-Performance Copper Active Centers for Alleviating Chemical Corneal Burns

泪小点内睫毛异位生长

Meibomian Glands and Tear Film Findings in Type 2 Diabetic Patients: A Cross-Sectional Study

Fenofibrate suppresses corneal neovascularization by regulating lipid metabolism through PPARα signaling pathway

Lacrimal Gland Microenvironment Changes After Obstruction of Lacrimal Gland Ducts

Hyperglycemia Induces Meibomian Gland Dysfunction

Can the cGAS-STING Pathway Play a Role in the Dry Eye?

Downregulation of p38 MAPK Signaling Pathway Ameliorates Tissue-Engineered Corneal Epithelium

Obstructive Sleep Apnea Affects Lacrimal Gland Function

Sleep deprivation induces corneal epithelial progenitor cell over-expansion through disruption of redox homeostasis in the tear film

Repressing c-Jun N-terminal kinase signaling mitigates retinal pigment epithelium degeneration in mice with failure to clear all-trans-retinal.

Safety and efficacy of repeated crosslinking assisted by transepithelial double-cycle iontophoresis in keratoconus progression after primary corneal crosslinking

Real-time confocal microscopy imaging of corneal cytoarchitectural changes induced by different stresses.

Autoantibodies against C5aR1, C3aR1, CXCR3, and CXCR4 are decreased in primary Sjogren's syndrome.

Novel Cell Culture Paradigm Prolongs Mouse Corneal Epithelial Cell Proliferative Activity in vitro and in vivo

Engineered bio-adhesive polyhedral oligomeric silsesquioxane hybrid nanoformulation of amphotericin B for prolonged therapy of fungal keratitis