百晓学者学者目录

刘艺锦

副教授、博导、教授、研究员、讲师，南开大学

精选作品

期刊论文

2026

Pistol核酶介导催化型RNA药物的设计与体内功能验证

张晶晶，王璞，赵明，刘艺锦

《中国药学杂志》

2026

Engineered pistol ribozymes selectively target KRAS G12V with enhanced efficacy by capping modification

Zhenzhen Li, Ming Zhao, Zhiqin Xi, Jie Bai, Ying Zhang, Xuelin Zhan, Yili Yang, Yijin Liu

Cell chemical biology

DOI

2026

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

Ming Zhao, Shan Qiao, Jie Bai, George Zhang, Zhiqin Xi, Zhenzhen Li, Xuelin Zhan, Ying Zhang, Xiaotong Yu, Yao Chen, Yijin Liu

Advanced Science

DOI

2025

Pistol Ribozyme-Driven Catalytic Spherical Nucleic Acid Integrates Gene and Chemotherapy for Enhanced Cancer Therapy

Jingjing Zhang, Minglei Zhao, Zhiqin Xi, Xiaoqian Liu, Linyi Feng, Jie Bai, Xuelin Zhan, Chunqiu Zhang, Adam C. Midgley, Yijin Liu

Journal of the American Chemical Society

DOI

2025

A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA

Man Lu, Zhiqiang Cao, Luoan Xiong, Hongying Deng, Kangkang Ma, Ning Liu, Yanding Qin, Shen‐Bo Chen, Jun‐Hu Chen, Yao Li, Yijin Liu, Zhongbo Yu

Communications Biology

DOI

2024

The structure and catalytic mechanism of a pseudoknot-containing hammerhead ribozyme

Xuelin Zhan, Timothy J. Wilson, Zhenzhen Li, Jingjing Zhang, Yili Yang, David M.J. Lilley, Yijin Liu

Nature Communications

DOI

2023

Constructed Risk Prognosis Model Associated with Disulfidptosis lncRNAs in HCC

Xiao-Wei Jia, Yi-Qi Wang, Yang Yang, Yueyue Fu, Yi-Jin Liu

International Journal of Molecular Sciences

DOI

2023

Creation of a Prognostic Model Using Cuproptosis-Associated Long Noncoding RNAs in Hepatocellular Carcinoma

Lihong Yang, Xiao-Wei Jia, Yueyue Fu, Jiao Tian, Yi-Jin Liu, Jianping Lin

International Journal of Molecular Sciences

DOI

研究方向

RNA分子的结构和催化机理

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