百晓学者学者目录

左正宏

副教授、助理教授、博士生导师、博导、教授,厦门大学

精选作品

期刊论文

2026

Neonatal exposure to PCB138 induces a polycystic ovary syndrome-like phenotype mediated by the aryl hydrocarbon receptor

Jinpeng Ruan, Pengtao Chen, Yixi Zhou, Zhiyuan Chen, Rongrong He, Min Xiao, Mingyue Chen, Chen Tang, Chao Shen, Jiali Cai, Chengyong He, Xiaoming Jiang, Zhenghong Zuo

Journal of Environmental Sciences

2026

Protective Effects of Nongxiang‐Type Tieguanyin on the Liver of D‐Galactose‐Induced Aging C57BL /6 Mice via the NF ‐ κB Signaling Pathway

Weihong Chen, Mingmei Li, Lingxiao Ye, Dongqin Huang, Jianjia Xiao, Yuchao Sang, Zizhen Wang, Jiehong Yang, Chengyong He, Jiabin Chen, Zhenghong Zuo, Xintan Chen

Food Science & Nutrition

2026

The guanine nucleotide exchange factor Rin-like is a repressor for renal uric acid excretion in human and mouse

Changshun Han, Chengyong He, Weiping Hu, Zhiyuan Chen, Xiaoyan Ding, Lingxiao Ye, Sihao Zhu, Lin Zhong, Shuni Zhuang, Tianyun Peng, Zixuan Li, Pan He, Lirong Lin, Yingyi Ren, Fengkai Ruan, Zizhen Wang, Yan Zhang, Fucong Zhang, Yitao Guo, Chunyan Yang, Baoding Zhang, Wei Wang, Changgui Li, Bo Wang, Jian Li, Chen‐Song Zhang, Xianming Deng, Zhenghong Zuo

Science Translational Medicine

2026

Theabrownin Alleviates Alcoholic Liver Disease in Mice by Improving Gut Microbiota and Tryptophan Metabolism

Lingxiao Ye, Zizhen Wang, Sihao Zhu, Xiaoyan Ding, Jianrong Han, Yuanwei Hao, Chengyong He, Yu Jiang, Zonghong Liu, Zhenghong Zuo

Molecular Nutrition & Food Research

2026

Early‐Life Exposure to InP/ZnS QDs Triggers Photoreceptor Apoptosis via ER Stress in Zebrafish: Implications for Nanomaterial‐Induced Retinal Toxicity

Naying Zheng, Junyu Liang, Ting Ouyang, Shu Zhao, Chunyan Yang, Zhenghong Zuo, Chengyong He

Small

2026

Black phosphorus nanomaterials induce hepatic lipid metabolism disorders by triggering oxidative stress and mitochondrial dysfunction

Sihao Zhu, Fengkai Ruan, Yan Zhang, Yucheng Leng, You Wu, Yuchen Sun, Chunyan Yang, Zhenghong Zuo, Shuzhen Chen

Particle and Fibre Toxicology

2026

Theabrownin Alleviates PCB138-Induced Intestinal Damage by Suppressing Oxidative Stress-Mediated Intestinal Epithelial Cell Necroptosis

Xiaoyan Ding, Yuting Zhong, Zhiyuan Chen, Chao Shen, Moye Ren, Lin Zhong, Changshun Han, Changqian Liu, Zitong Huang, Junwei Chen, Wei Zeng, Chengyong He, Zhenghong Zuo

Journal of Agricultural and Food Chemistry

2026

PCBs exposure and renal injury: comprehensive assessment strategy based upon TRAEC strategy

Zhiyuan Chen, Changqian Liu, Linlin Zhang, Jianrong Han, Xiaoyan Ding, Changshun Han, Sihao Zhu, Jiabao Cao, Jiaxin Song, Fucong Zhang, Jian Li, Zhenghong Zuo, Chengyong He

Journal of Environmental Management

2026

Esketamine Exposure Affects Neurodevelopment and Glutamate‐NMDAR Signaling in Zebrafish Larvae

Jingyi Wang, Shuo Huang, Tingting Lin, Zhineng Fu, Zhenghong Zuo, Z F Chen, Chengyong He

Journal of Biochemical and Molecular Toxicology

2026

Typical persistent organic pollutant exposure induces body axial curvature through binding to Kdm1a transcriptionally activating expression of urp2 in zebrafish

Pengtao Chen, Jinpeng Ruan, Min Xiao, Fanzheng Xue, Zhiyuan Chen, Rongrong He, Chen Tang, Qianqian Liu, Chunyan Yang, Chengyong He, Zhenghong Zuo

Journal of Hazardous Materials

2026

Black Phosphorus Nanosheets Penetrate the Blood–Testis Barrier and Induce Reproductive Toxicity in Male Mice

Suhua Jiang, Fengkai Ruan, Fucong Zhang, Zewei Long, Xiaoyan Ding, Sihao Zhu, Zhineng Fu, Zhenghong Zuo, Xiaoming Jiang, Chengyong He

Environment & Health

2026

Exposure to titanium and nickel as the novel risk factors for PCOS: Evidence from a case control study in Xiamen, China

Zhineng Fu, Lanlan Liu, Jingyi Wang, Fengkai Ruan, Yurong Chen, Liying Zhou, Chunyan Yang, Jiali Cai, Runzeng Liu, Chengyong He, Xiaoming Jiang, Zhenghong Zuo

Journal of Environmental Sciences

2025

培养生命科学一流人才的实践育人体系改革与探索

徐虹,程喆,邬小兵,左正宏,邓贤明,李勤喜

《高校生物学教学研究(电子版)》

2025

菟丝子通过调控光转导通路改善嘧菌胺诱导的斑马鱼视觉损伤及潜在活性成分鉴定(英文)

杨亚玲,赵梓邯,郑亚倩,郑娜英,杨莲,AnferneeKai Wing Tse,左正宏,何承勇,杨健,郭兰萍

Science of Traditional Chinese Medicine

2025

生物技术概论

左正宏

《科学出版社》

2025

Cuscutae Semen ameliorates mepanipyrim-induced visual impairment in zebrafish via the phototransduction pathway with identification of potential active constituents

Yaling Yang, Zihan Zhao, Yaqian Zheng, Naying Zheng, Lian Yang, Anfernee Kai‐Wing Tse, Zhenghong Zuo, Chengyong He, Jian Yang, Lanping Guo

Science of Traditional Chinese Medicine

2025

Early life exposure to environmental levels of PCB138 induces lipid metabolism disorders through activating aryl hydrocarbon receptor in female mice

Sihao Zhu, Rongrong He, Jinpeng Ruan, Pengtao Chen, Yan Zhang, Chunyan Yang, Wei Wang, Chengyong He, Zhenghong Zuo

Environmental Research

2025

Oocyte-specific Ahr deletion disrupts folliculogenesis and female fertility in mice

Pengtao Chen, Jinpeng Ruan, Fanzheng Xue, Xuejuan Dai, Chen Tang, Mingyue Chen, Nengming Xiao, Zhijian Cai, Chunyan Yang, Chengyong He, Weimin Wang, Zhenghong Zuo

Molecular and Cellular Endocrinology

2025

Mechanisms of metabolic-associated fatty liver disease induced by 48-week PCB138 exposure and theabrownin intervention

Jian-Rong Han, Changqian Liu, Zhiyuan Chen, Fengkai Ruan, Fanzheng Xue, Lingxiao Ye, Yi Yu, Zhenghong Zuo, Chengyong He

Environment International

2025

Fullerenol Doped Matrigel Promotes Maturation of Intestinal Organoids by Inhibiting Oxidative Stress and Apoptosis

Fengkai Ruan, Longyang Li, Mingtao Wu, Fanzheng Xue, Zhineng Fu, Fucong Zhang, Zhenghong Zuo, Liang Bu, Fanwei Zeng, Chengyong He

ACS Applied Bio Materials

2025

Neburon induced cardiotoxicity in embryonic and adult male zebrafish via over-activation of the Ahr-Notch1 signaling pathway

Chen Tang, Lide Su, Fanzheng Xue, Yiwen Sun, Fucong Zhang, Chengyong He, Zhenghong Zuo, Zonghong Liu

Environmental Pollution

2025

Evaluating the Effects of Neburon Exposure on Ovarian Folliculogenesis Using Zebrafish and Mouse Granulosa Cell Line

Chen Tang, Ying Zhang, Fucong Zhang, Yiwen Sun, Yue Chen Zhu, Fanzheng Xue, Zhenhong Wang, You Wu, Jinpeng Ruan, Yiming Yue, Chunyan Yang, Wei Ge, Chengyong He, Zhenghong Zuo

Environmental Health Perspectives

2025

Disruption of surfactant homeostasis leads to impaired inflation of zebrafish posterior swim bladder by non-dioxin-like PCB40

Min Xiao, Chengyong He, Pengtao Chen, Jinpeng Ruan, Yu Liang Jiang, Zhenghong Zuo, Chunyan Yang

Environmental Chemistry and Ecotoxicology

2025

Distribution and ecological risk of typical AhR agonistic pesticides in China's marginal seas and their reproductive toxicities on Oryzias melastigma

Yuxuan Zhang, Chengyong He, Jingyi Wang, Zixuan Li, Junling Xiao, Kaiwen Gu, Zhenghong Zuo, Chunyan Yang

Environmental Chemistry and Ecotoxicology

2024

Subacute exposure to black phosphorus quantum dots induces cardiac fibrosis and the potential role of gut microbiota

Jian‐Rong Han, Fengkai Ruan, Chunyan Yang, Zhenghong Zuo, Zonghong Liu, Chengyong He

Journal of Environmental Sciences

2024

Nano-sized titanium dioxide exposure induces non-hyperandrogenic polycystic ovarian syndrome in rats by increasing aromatase and apoptosis in granulosa cells

Weidong Zhou, Wenjing Zhang, Zhineng Fu, Chen Tang, Pengtao Chen, Pengtao Chen, Ruofan Huang, Chunyan Yang, Shuzhen Chen, Shuzhen Chen, Zhenghong Zuo, Chengyong He, Mingyue Chen, Chengyong He

Journal of Environmental Sciences

2024

Developmental exposure to echimidine induces locomotor hyperactivity in zebrafish larvae via inhibiting acetylcholinesterase activity

Tingting Lin, Siyu Chen, Yingyi Ren, Junyu Liang, Zhenghong Zuo, Zhiqiang Luo, Jian Yang, Chengyong He

Journal of Environmental Sciences

2024

Effects and mechanisms of theabrownin from black tea in improving hyperuricemia: Evidence from animal study and clinical trial

Xiaoyan Ding, Qin Yuan, Changshun Han, Chao Shen, Mingyue Chen, Hanying Yin, Hongbin Zhong, Chunyan Yang, Jiyi Huang, Chengyong He, Zhenghong Zuo

International Journal of Biological Macromolecules

2024

Black phosphorus nanomaterials mediate size-dependent acute lung injury by promoting macrophage polarization

Mingtao Wu, Jie Zeng, Wanru Huang, Fengkai Ruan, Zhenghong Zuo, Liang Bu, Chengyong He

Food and Chemical Toxicology

2024

Black phosphorus quantum dots induce lipid accumulation through PPARγ activation and mitochondrial dysfunction in adipocytes

Sihao Zhu, Fengkai Ruan, Lingxiao Ye, Suhua Jiang, Chunyan Yang, Zhenghong Zuo, Chengyong He

The Science of The Total Environment

2024

Quantum Dots‐caused Retinal Degeneration in Zebrafish Regulated by Ferroptosis and Mitophagy in Retinal Pigment Epithelial Cells through Inhibiting Spliceosome

Naying Zheng, Tingting Liao, Chuchu Zhang, Zheyang Zhang, Sen Rong Yan, Xiao-Han Xi, Fengkai Ruan, Chunyan Yang, Qingliang Zhao, Wenbo Deng, Jialiang Huang, Zi‐Tao Huang, Zhifeng Chen, Xiang Wang, Qingming Qu, Zhenghong Zuo, Chengyong He

Advanced Science

2024

Effects of whole life-cycle exposure to carbaryl on reproduction of female marine medaka (Oryzias melastigma) and their offspring

Yuxin Chen, Yuxuan Zhang, Qun Jiang, Chen Tang, Qian Wang, Chengyong He, Zhenghong Zuo, Chunyan Yang

The Science of The Total Environment

2024

Phenanthrene-induced hyperuricemia with intestinal barrier damage and the protective role of theabrownin: Modulation by gut microbiota-mediated bile acid metabolism

Changqian Liu, Fengkai Ruan, Zhiyuan Chen, Jian-Rong Han, Xiaoyan Ding, Changshun Han, Lingxiao Ye, Chunyan Yang, Yi Yu, Zhenghong Zuo, Chengyong He

The Science of The Total Environment

2024

Multi-omics integration identifies ferroptosis involved in black phosphorus quantum dots-induced renal injury

Fengkai Ruan, Changqian Liu, Jie Zeng, Fucong Zhang, Yu Jiang, Zhenghong Zuo, Chengyong He

The Science of The Total Environment

2024

Resveratrol ameliorates cyprodinil-induced zebrafish cardiac developmental defects as an aryl hydrocarbon receptor antagonist

Ruyu Zhan, Fushan Zhou, Chaoyang Liu, Chuanchang Chen, Mingmei Li, Dongqin Huang, Naying Zheng, Tingting Lin, Zhenghong Zuo, Chengyong He, Xintan Chen

Environmental Science and Pollution Research

2024

Comparative Analysis of Therapeutic Efficacy and Adverse Reactions among Various Thrombolytic Agents

Chenxi Xie, Naying Zheng, Mingmei Li, Zhiyang Zhang, Dongqin Huang, Meizhu Xiao, Dongdong Chen, Chengyong He, Zhenghong Zuo, Xintan Chen

Toxics

2024

WWC1 upregulation accelerates hyperuricemia by reduction in renal uric acid excretion through Hippo signaling pathway

Changshun Han, Chengyong He, Xiaoyan Ding, Zixuan Li, Tianyun Peng, Chen‐Song Zhang, Haibing Chen, Zhenghong Zuo, Jiyi Huang, Weiping Hu

Journal of Biological Chemistry

2024

Long-term carbaryl exposure leads to behavioral abnormalities and reproductive toxicity in male marine medaka through apoptosis-mediated HPA and HPG axes dysregulation

Yuxin Chen, Qun Jiang, Yuxuan Zhang, Zhenghong Zuo, Chunyan Yang

Ecotoxicology and Environmental Safety

2024

Letrozole induced a polycystic ovary syndrome model in zebrafish by interfering with the hypothalamic-pituitary-gonadal axis

Fucong Zhang, Chen Tang, Jingyi Wang, Tingting Lin, Wei Ge, Chengyong He, Chunyan Yang, Zhenghong Zuo

Environmental Pollution

2024

Gut microbiota dysbiosis mediates mouse kidney fibrosis induced by black phosphorus quantum dots

Fengkai Ruan, Jie Zeng, Changqian Liu, Jianrong Han, Naying Zheng, Kun Li, Hanying Yin, Mingtao Wu, Xiaoyan Ding, Changshun Han, Lingtao Yang, Chunyan Yang, Dai Wang, Nengming Xiao, Zhenghong Zuo, Chengyong He

Nano Today

2023

Long-term exposure to aryl hydrocarbon receptor agonist neburon induces reproductive toxicity in male zebrafish (Danio rerio)

Fucong Zhang, Chen Tang, Yue Chen Zhu, Qian Wang, Xin Huang, Chunyan Yang, Chengyong He, Zhenghong Zuo

Journal of Environmental Sciences

2023

Black phosphorus quantum dots induce myocardial inflammatory responses and metabolic disorders in mice

Chao Shen, Xiaoyan Ding, Jinpeng Ruan, Fengkai Ruan, Weiping Hu, Jiyi Huang, Chengyong He, Yi Yu, Zhenghong Zuo

Journal of Environmental Sciences

2023

Tributyltin causes generational neurodevelopmental toxicity and the protective effect of folic acid in zebrafish

Haoxing Cai, Naying Zheng, Chen Tang, Yuxuan Zhang, Zhenghong Zuo, Chengyong He

Journal of Environmental Sciences

2023

Corrigendum to “Kidney injury contributes to edema of zebrafish larvae caused by quantum dots” [Sci. Total Environ. 908 (2024) 168420]

Luanjin Wang, Cixin Liang, Naying Zheng, Chunyan Yang, Sen Rong Yan, Xiang Wang, Zhenghong Zuo, Chengyong He

The Science of The Total Environment

2023

Kidney injury contributes to edema of zebrafish larvae caused by quantum dots

Luanjin Wang, Cixin Liang, Naying Zheng, Chunyan Yang, Sen Rong Yan, Xiang Wang, Zhenghong Zuo, Chengyong He

The Science of The Total Environment

2023

Icariin induces developmental toxicity via thyroid hormone disruption in zebrafish larvae

Meifang Wu, Naying Zheng, Xiaoxiao Zhan, Jianzhang He, Min Xiao, Zhenghong Zuo, Chengyong He

Food and Chemical Toxicology

2023

Exposure to echimidine impairs the heart development and function of zebrafish larvae

Tingting Lin, Li Zhou, Zhibin Chen, Luanjin Wang, Jian Yang, Sheng Wang, Xintan Chen, Zhenghong Zuo, Chengyong He, Lanping Guo

Ecotoxicology and Environmental Safety

2023

Topically applied fullerenols protect against radiation dermatitis by scavenging reactive oxygen species

Hanying Yin, You Gao, Weiguang Chen, Chen Tang, Zihan Zhu, Kun Li, Siyu Xia, Changshun Han, Xiaoyan Ding, Fengkai Ruan, Han‐Rui Tian, Changfeng Zhu, Suyuan Xie, Zhenghong Zuo, Lixin Liao, Chengyong He

Discover Nano

2023

Transgenerational Effects and Mechanisms of Tributyltin Exposure on Neurodevelopment in the Male Offspring of Rats

Haoxing Cai, Mingyue Chen, Yang Gao, Jinpeng Ruan, Chengyong He, Zhenghong Zuo

Environmental Science & Technology

2023

Estradiol protects female mice from hyperuricemia induced by PCB138 exposure

Changqian Liu, Jinpeng Ruan, Fengkai Ruan, Xiaoyan Ding, Changshun Han, Chaoqun Huang, Hongbin Zhong, Chengyong He, Zhenghong Zuo, Jiyi Huang

Ecotoxicology and Environmental Safety

2023

Ferrous Oxide Nanoparticles Induced Abnormal Cardiac Development in Zebrafish Through Hypoxia and Ferroptosis

Naying Zheng, Xintan Chen, Ruyu Zhan, Tingting Liao, Yiyue Shi, Xiaolian Sun, Shuzhen Chen, Zhenghong Zuo

Chemical Research in Chinese Universities

2023

The hepatoprotective effects of Herbt Tea Essences on phenanthrene-induced liver damage in mice

Lingxiao Ye, Xiaoyan Ding, Changqian Liu, Fengkai Ruan, Hongbin Zhong, Rongfu Lv, Yi Yu, Chengyong He, Zhenghong Zuo, Jiyi Huang

Ecotoxicology and Environmental Safety

2023

Toxicity and ecological risk assessment for two AhR agonistic pesticides mepanipyrim and cyprodinil and their metabolites

Chao Shen, Chen Tang, Kongyang Zhu, Chengyong He, Chunyan Yang, Zhenghong Zuo

Environmental Science and Pollution Research

2023

Chronic diflubenzuron exposure causes reproductive toxic effects in female marine medaka (Oryzias melastigma)

Yuanyuan Bao, Yuxin Chen, Yixi Zhou, Qian Wang, Zhenghong Zuo, Chunyan Yang

Aquatic Toxicology

2022

Mepanipyrim induces visual developmental toxicity and vision-guided behavioral alteration in zebrafish larvae

Chao Shen, Yimei Cai, Jialing Li, Chengyong He, Zhenghong Zuo

Journal of Environmental Sciences

2022

Mepanipyrim induces cardiotoxicity of zebrafish (Danio rerio) larvae via promoting AhR-regulated COX expression pathway

Chao Shen, Jing He, Kongyang Zhu, Naying Zheng, Yue Yu, Chengyong He, Chunyan Yang, Zhenghong Zuo

Journal of Environmental Sciences

2022

Herbal Tea Essences (HTE) Ameliorate HFD-Induced Obesity

Yue Wang, Ying Han, Rongfu Lv, Chengyong He, Zhenghong Zuo, Ying Chen, Jiyi Huang

Evidence-based Complementary and Alternative Medicine

2022

Black phosphorus quantum dots cause glucose metabolism disorder and insulin resistance in mice

Jie Zeng, Fengkai Ruan, Mingtao Wu, Jiaying Xu, Zhenghong Zuo, Yi Yu, Chengyong He

Ecotoxicology and Environmental Safety

2022

Role of RNA m6A modification in titanium dioxide nanoparticle-induced acute pulmonary injury: An in vitro and in vivo study

Fengkai Ruan, Changqian Liu, Yi Wang, Xisen Cao, Zhen Tang, Jiaying Xu, Jie Zeng, Hanying Yin, Naying Zheng, Chunyan Yang, Zhenghong Zuo, Chengyong He

Environmental Pollution

2022

Reproductive toxicity of long-term exposure to environmental relevant concentrations of cyprodinil in female zebrafish (Danio rerio)

Chen Tang, Yue Chen Zhu, Chunyan Yang, Chengyong He, Zhenghong Zuo

The Science of The Total Environment

2022

Aryl hydrocarbon receptor agonist diuron and its metabolites cause reproductive disorders in male marine medaka (Oryzias melastigma)

Yixi Zhou, Kongyang Zhu, Qian Wang, Meng Chen, Chengyong He, Chunyan Yang, Zhenghong Zuo

Chemosphere

2022

Acute and Subacute Safety Evaluation of Black Tea Extract (Herbt Tea Essences) in Mice

Xiaoyan Ding, Changshun Han, Weiping Hu, Chengqing Fu, Yixi Zhou, Zheng Wang, Qingyan Xu, Rongfu Lv, Chengyong He, Zhenghong Zuo, Jiyi Huang

Toxics

2022

Early life PCB138 exposure induces kidney injury secondary to hyperuricemia in male mice

Fengkai Ruan, Changqian Liu, Weiping Hu, Jinpeng Ruan, Xiaoyan Ding, Lu Zhang, Chunyan Yang, Zhenghong Zuo, Chengyong He, Jiyi Huang

Environmental Pollution

2022

Parental diuron exposure causes lower hatchability and abnormal ovarian development in offspring of medaka (Oryzias melastigma)

Yuanyuan Bao, Yixi Zhou, Ruiyao Tang, Yanling Yao, Zhenghong Zuo, Chunyan Yang

Aquatic Toxicology

2022

Nanoparticle-Induced m6A RNA Modification: Detection Methods, Mechanisms and Applications

Yi Wang, Fengkai Ruan, Zhenghong Zuo, Chengyong He

Nanomaterials

2022

Developmental toxicity and neurotoxicity assessment of R-, S-, and RS-propylene glycol enantiomers in zebrafish (Danio rerio) larvae

Chao Shen, Xijing Zhao, Chengyong He, Zhenghong Zuo

Environmental Science and Pollution Research

2022

The Valence State of Iron-Based Nanomaterials Determines the Ferroptosis Potential in a Zebrafish Model

Naying Zheng, Xiaolian Sun, Yiyue Shi, Luheng Chen, Luanjin Wang, Haoxing Cai, Changshun Han, Tingting Liao, Chunyan Yang, Zhenghong Zuo, Chengyong He

The Science of The Total Environment

2021

黑磷纳米片应用及生物毒性研究进展

向思靓,曾洁,阮锋凯,左正宏,何承勇

《生态毒理学报》

2021

Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication

Mingyue Chen, Chengyong He, Kongyang Zhu, Zihan Chen, Zixiao Meng, Xiaoming Jiang, Jiali Cai, Chunyan Yang, Zhenghong Zuo

Theranostics

2021

Sacran polysaccharide improves atopic dermatitis through inhibiting Th2 type immune response

Songwen Ren, You Gao, Luanjin Wang, Ce Qiu, Lingtao Yang, Li Li, Yueyue Xiao, Nengming Xiao, Lixin Liao, Zhenghong Zuo, Chunyan Yang, Chengyong He

Life Sciences

2021

Long-term exposure to cyprodinil causes abnormal zebrafish aggressive and antipredator behavior through the hypothalamic–pituitary–interrenal axis

Chen Tang, Yue Chen Zhu, Yibimu Laziyan, Chunyan Yang, Chengyong He, Zhenghong Zuo

Aquatic Toxicology

2021

Acute and subacute oral toxicity of propylene glycol enantiomers in mice and the underlying nephrotoxic mechanism

Yixi Zhou, Xijing Zhao, Weiping Hu, Fengkai Ruan, Chengyong He, Jiyi Huang, Zhenghong Zuo

Environmental Pollution

2021

Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma)

Yixi Zhou, Xue Han, Yuanyuan Bao, Zihan Zhu, Jiali Huang, Chunyan Yang, Chengyong He, Zhenghong Zuo

Aquatic Toxicology

2021

Long-term exposure to environmental level of phenanthrene causes adaptive immune response and fibrosis in mouse kidneys

Fengkai Ruan, Lifang Wu, Hanying Yin, Lu Fang, Chen Tang, Si‐Yang Huang, Longxiang Fang, Zhenghong Zuo, Chengyong He, Jiyi Huang

Environmental Pollution

2021

RNA m6A Modification Alteration by Black Phosphorus Quantum Dots Regulates Cell Ferroptosis: Implications for Nanotoxicological Assessment

Fengkai Ruan, Jie Zeng, Hanying Yin, Shengwei Jiang, Xisen Cao, Naying Zheng, Changshun Han, Chuchu Zhang, Zhenghong Zuo, Chengyong He

Small Methods

2020

Comparison of developmental toxicity of different surface modified CdSe/ZnS QDs in zebrafish embryos

Naying Zheng, Jinhui Yan, Qian Wang, Chao Song, Zhenghong Zuo, Chengyong He

Journal of Environmental Sciences

2020

The interference effects of bisphenol A on the synthesis of steroid hormones in human ovarian granulosa cells

Junxia Shi, Chenyu Liu, Mingyue Chen, Jinhui Yan, Chonggang Wang, Zhenghong Zuo, Chengyong He

Environmental Toxicology

2020

Improvement in the screening performance of potential aryl hydrocarbon receptor ligands by using supervised machine learning

Kongyang Zhu, Chao Shen, Chen Tang, Yixi Zhou, Chengyong He, Zhenghong Zuo

Chemosphere

2020

Screening of potential oestrogen receptor α agonists in pesticides via in silico, in vitro and in vivo methods

Chao Shen, Kongyang Zhu, Jinpeng Ruan, Jialing Li, Yi Wang, Meirong Zhao, Chengyong He, Zhenghong Zuo

Environmental Pollution

2020

Zebrafish (Danio rerio) as an excellent vertebrate model for the development, reproductive, cardiovascular, and neural and ocular development toxicity study of hazardous chemicals

Chao Shen, Zhenghong Zuo

Environmental Science and Pollution Research

2020

Exposure to the AhR agonist cyprodinil impacts the cardiac development and function of zebrafish larvae

Chen Tang, Chao Shen, Kongyang Zhu, Yixi Zhou, Yung‐Jen Chuang, Chengyong He, Zhenghong Zuo

Ecotoxicology and Environmental Safety

2020

Developmental exposure to mepanipyrim induces locomotor hyperactivity in zebrafish (Danio rerio) larvae

Chao Shen, Yixi Zhou, Chen Tang, Chengyong He, Zhenghong Zuo

Chemosphere

2020

Black Phosphorus Quantum Dots Cause Nephrotoxicity in Organoids, Mice, and Human Cells

Chengyong He, Fengkai Ruan, Shengwei Jiang, Jie Zeng, Hanying Yin, Rong Liu, Yongxing Zhang, Laiqiang Huang, Chonggang Wang, Shaohua Ma, Zhenghong Zuo

Small

2020

Neonatal exposure to environment-relevant levels of tributyltin leads to uterine dysplasia in rats

Mingyue Chen, Jiaojiao Guo, Jinpeng Ruan, Zhibing Yang, Chengyong He, Zhenghong Zuo

The Science of The Total Environment

2020

Generation and application of a Tg(cyp1a:egfp) transgenic marine medaka (Oryzias melastigma) line as an in vivo assay to sensitively detect dioxin-like compounds in the environment

Yixi Zhou, Chao Shen, Jinpeng Ruan, Chengyong He, Meng Chen, Chonggang Wang, Zhenghong Zuo

Journal of Hazardous Materials

2020

Graphene oxide quantum dot exposure induces abnormalities in locomotor activities and mechanisms in zebrafish ( Danio rerio )

Jinhui Yan, Shujing Chen, Zhenghong Zuo, Chengyong He, Muqing Yi

Journal of Applied Toxicology

2019

书院制国际化办学模式的实践探索——以博伊特勒书院为例

江子扬,左正宏,张弘

《黑龙江教育(高教研究与评估)》

2019

AhR Agonist Activity Confirmation of Polyhalogenated Carbazoles (PHCZs) Using an Integration of in Vitro, in Vivo, and in Silico Models

Chenyang Ji, Chao Shen, Yixi Zhou, Kongyang Zhu, Zhe Sun, Zhenghong Zuo, Meirong Zhao

Environmental Science & Technology

2019

Adolescent exposure to environmental level of PCBs (Aroclor 1254) induces non-alcoholic fatty liver disease in male mice

Jinpeng Ruan, Jiaojiao Guo, Yameng Huang, Yunzi Mao, Zhenggang Yang, Zhenghong Zuo

Environmental Research

2019

Exposure to Aroclor 1254 differentially affects the survival of pancreatic β-cells and α-cells in the male mice and the potential reason

Lu Fang, Shiqi Zhang, Kunlin Ou, Zhenghong Zuo, Ang Yu, Chonggang Wang

Ecotoxicology and Environmental Safety

2019

Tributyltin exposure disturbs hepatic glucose metabolism in male mice

Jing Xu, Kunlin Ou, Chuqiao Chen, Binshui Li, Jiaojiao Guo, Zhenghong Zuo, Chonggang Wang

Toxicology

2019

A pilot study on polycystic ovarian syndrome caused by neonatal exposure to tributyltin and bisphenol A in rats

Zhibing Yang, Junxia Shi, Zhizhun Guo, Mingyue Chen, Chonggang Wang, Chengyong He, Zhenghong Zuo

Chemosphere

2019

Exposure to low-level metalaxyl impacts the cardiac development and function of zebrafish embryos

Yuqiong Wu, Ying Zhang, Meng Chen, Qihong Yang, Shanshan Zhuang, Liangju Lv, Zhenghong Zuo, Chonggang Wang

Journal of Environmental Sciences

2019

Exposure to Aroclor 1254 persistently suppresses the functions of pancreatic β-cells and deteriorates glucose homeostasis in male mice

Zhihui Xi, Lu Fang, Jing Xu, Bingshui Li, Zhenghong Zuo, Liangju Lv, Chonggang Wang

Environmental Pollution

2019

Maternal Supplementation with β‐Carotene During Pregnancy Disturbs Lipid Metabolism and Glucose Homoeostasis in F1 Female Mice

Jiaojiao Guo, Bingshui Li, Zhenghong Zuo, Meng Chen, Chonggang Wang

Molecular Nutrition & Food Research

2019

Phenotypic characterization, virulence, and immunogenicity of Pseudomonas plecoglossicida rpoE knock-down strain

Lixing Huang, Youyu Zhang, Rongchao He, Zhenghong Zuo, Zhu-Hua Luo, Wei Xu, Qingpi Yan

Fish & Shellfish Immunology

2018

以课题式实验教学提高学生科研兴趣和科研能力的探索——以“遗传学实验”为例

章军,王勤,王立红,陈林娇,徐虹,左正宏,李勤喜,周大旺

《高校生物学教学研究(电子版)》

2018

“双一流”背景下对生命科学领域拔尖人才培养体系的探索

徐虹,王勤,郑毅芳,左正宏,周大旺,李勤喜

《高校生物学教学研究(电子版)》

2018

本科生导师制在人才培养工作中的探索与实践——以厦门大学生命科学学院为例

江子扬,左正宏,郑毅芳

《河南教育(高教)》

2018

生物科学本科教学质量保障监控体系的构建与探索

王勤,李勤喜,郑毅芳,田静,左正宏,宋思扬,林圣彩,周大旺

《高校生物学教学研究(电子版)》

2018

国家级实验教学示范中心综合育人功能

陈林姣,石艳,李勤喜,周大旺,左正宏

《实验技术与管理》

2018

Bioassay system for the detection of aryl hydrocarbon receptor agonists in waterborne pesticides using zebrafish cyp1a1 promoter-luciferase recombinant hepatic cells

Yixi Zhou, Chao Shen, Hong Du, Yuanyuan Bao, Chengyong He, Chonggang Wang, Zhenghong Zuo

Chemosphere

2018

The protective effects of Nile tilapia (Oreochromis niloticus) scale collagen hydrolysate against oxidative stress induced by tributyltin in HepG2 cells

Jinpeng Ruan, Junde Chen, Jie Zeng, Zhenggang Yang, Chonggang Wang, Zhuan Hong, Zhenghong Zuo

Environmental Science and Pollution Research

2018

Generation of a Tg(cyp1a-12DRE:EGFP) transgenic zebrafish line as a rapid in vivo model for detecting dioxin-like compounds

Chao Shen, Yixi Zhou, Jinpeng Ruan, Yung‐Jen Chuang, Chonggang Wang, Zhenghong Zuo

Aquatic Toxicology

2018

Combined effects of ocean acidification and crude oil pollution on tissue damage and lipid metabolism in embryo–larval development of marine medaka (Oryzias melastigma)

Lingbin Sun, Jinpeng Ruan, Mengchao Lu, Meng Chen, Zhongliang Dai, Zhenghong Zuo

Environmental Geochemistry and Health

2018

Embryonic exposure to benzo(a)pyrene inhibits reproductive capability in adult female zebrafish and correlation with DNA methylation

Dongxu Gao, Jing Lin, Kunlin Ou, Ying Chen, Hongbin Li, Qinhua Dai, Zhenni Yu, Zhenghong Zuo, Chonggang Wang

Environmental Pollution

2018

Fenbuconazole exposure impacts the development of zebrafish embryos

Yuqiong Wu, Qihong Yang, Meng Chen, Ying Zhang, Zhenghong Zuo, Chonggang Wang

Ecotoxicology and Environmental Safety

2018

Exposure to environmental level phenanthrene induces a NASH-like phenotype in new born rat

Jiaojiao Guo, Chonggang Wang, Zhizhun Guo, Zhenghong Zuo

Environmental Pollution

2017

四种新型农药对斑马鱼胚胎发育的毒性效应

吴玉琼,陈莹,胡永乐,左正宏,王重刚

《生物技术通报》

2017

二噁类化合物的生物检测方法研究进展

阮金鹏,周懿翕,沈超,左正宏

《环境科学与技术》

2017

Protective effects of fucoxanthin and fucoxanthinol against tributyltin-induced oxidative stress in HepG2 cells

Jie Zeng, Yiping Zhang, Jinpeng Ruan, Zhenggang Yang, Chonggang Wang, Zhuan Hong, Zhenghong Zuo

Environmental Science and Pollution Research

2017

The developmental effects of low-level procymidone towards zebrafish embryos and involved mechanism

Yuqiong Wu, Zhenghong Zuo, Meng Chen, Yixi Zhou, Qihong Yang, Shanshan Zhuang, Chonggang Wang

Chemosphere

2017

Maternal and embryonic exposure to the water soluble fraction of crude oil or lead induces behavioral abnormalities in zebrafish (Danio rerio), and the mechanisms involved

Yuanchuan Wang, Chao Shen, Chonggang Wang, Yixi Zhou, Dongxu Gao, Zhenghong Zuo

Chemosphere

2017

Exposure to difenoconazole inhibits reproductive ability in male marine medaka ( Oryzias melastigma )

Xiaocui Dong, Lemeng Zhang, Meng Chen, Zhibin Yang, Zhenghong Zuo, Chonggang Wang

Journal of Environmental Sciences

2017

Rücktitelbild: Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals (Angew. Chem. 11/2017)

Xiangzhao Ai, Linna Lyu, Yang Zhang, Yanxia Tang, Jing Mu, Fang Liu, Yixi Zhou, Zhenghong Zuo, Gang Liu, Bengang Xing

Angewandte Chemie

2017

Back Cover: Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals (Angew. Chem. Int. Ed. 11/2017)

Xiangzhao Ai, Linna Lyu, Yang Zhang, Yanxia Tang, Jing Mu, Fang Liu, Yixi Zhou, Zhenghong Zuo, Gang Liu, Bengang Xing

Angewandte Chemie International Edition

2017

Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals

Xiangzhao Ai, Linna Lyu, Yang Zhang, Yanxia Tang, Jing Mu, Fang Liu, Yixi Zhou, Zhenghong Zuo, Gang Liu, Bengang Xing

Angewandte Chemie

2017

Early-Life Benzo[a]Pyrene Exposure Causes Neurodegenerative Syndromes in Adult Zebrafish (Danio rerio) and the Mechanism Involved

Dongxu Gao, Chonggang Wang, Zhihui Xi, Yixi Zhou, Yuanchuan Wang, Zhenghong Zuo

Toxicological Sciences

2016

遵循人才培养规律的生物科学专业课程体系建设探讨

王勤,李勤喜,郑毅芳,田静,左正宏,宋思扬,林圣彩,周大旺

《高校生物学教学研究(电子版)》

2016

Maternal exposure to the water soluble fraction of crude oil, lead and their mixture induces autism-like behavioral deficits in zebrafish (Danio rerio) larvae

Yuanchuan Wang, Hongxiu Zhong, Chonggang Wang, Dongxu Gao, Yulin Zhou, Zhenghong Zuo

Ecotoxicology and Environmental Safety

2016

Polychlorinated biphenyls impair endometrial receptivity in vitro via regulating mir-30d expression and epithelial mesenchymal transition

Jiali Cai, Lanlan Liu, Yuqin Hu, Xiaoming Jiang, Hui-Ling Qiu, Aiguo Sha, Chonggang Wang, Zhenghong Zuo, Jianzhi Ren

Toxicology

2016

Bioaccumulation and the expression of hepatic cytochrome P450 genes in marine medaka ( Oryzias melastigma ) exposed to difenoconazole

Lemeng Zhang, Xiaocui Dong, Chonggang Wang, Zhenghong Zuo, Meng Chen

Journal of Environmental Sciences

2016

Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation

Lixing Huang, Zhihui Xi, Chonggang Wang, Youyu Zhang, Zhibing Yang, Shiqi Zhang, Yixin Chen, Zhenghong Zuo

Scientific Reports

2016

Association of serum organochlorine pesticides concentrations with reproductive hormone levels and polycystic ovary syndrome in a Chinese population

Zhizhun Guo, Huiling Qiu, Lingling Wang, Lijun Wang, Chonggang Wang, Meng Chen, Zhenghong Zuo

Chemosphere

2015

Hexabromocyclododecane exposure induces cardiac hypertrophy and arrhythmia by inhibiting miR-1 expression via up-regulation of the homeobox gene Nkx2.5

Meifang Wu, Di Wu, Chonggang Wang, Zhizhun Guo, Bowen Li, Zhenghong Zuo

Journal of Hazardous Materials

2015

Chronic exposure to low benzo[a]pyrene level causes neurodegenerative disease-like syndromes in zebrafish (Danio rerio)

Dongxu Gao, Mei-Fang Wu, Chonggang Wang, Yuanchuan Wang, Zhenghong Zuo

Aquatic Toxicology

2015

Chronic Exposure to Aroclor 1254 Disrupts Glucose Homeostasis in Male Mice via Inhibition of the Insulin Receptor Signal Pathway

Shiqi Zhang, Tian Wu, Meng Chen, Zhizhun Guo, Zhibin Yang, Zhenghong Zuo, Chonggang Wang

Environmental Science & Technology

2015

Reproductive and transgenerational toxicities of phenanthrene on female marine medaka ( Oryzias melastigma )

Lingbin Sun, Zhenghong Zuo, Meng Chen, Yixin Chen, Chonggang Wang

Aquatic Toxicology

2015

Association of Serum Heavy Metals and Trace Element Concentrations with Reproductive Hormone Levels and Polycystic Ovary Syndrome in a Chinese Population

Guanchao Zheng, Lijun Wang, Zhizhun Guo, Lingbin Sun, Lingling Wang, Chonggang Wang, Zhenghong Zuo, Huiling Qiu

Biological Trace Element Research

2015

Influences of Domoic Acid Exposure on Cardiac Development and the Expression of Cardiovascular Relative Genes in Zebrafish (Daniorerio) Embryos

Zhuan Hong, Youyu Zhang, Zhenghong Zuo, Ruilin Zhu, Yahui Gao

Journal of Biochemical and Molecular Toxicology

2015

Decrease in prosaposin in spermatozoon is associated with polychlorinated biphenyl exposure.

Jiali Cai, Lingbin Sun, Zhizhun Guo, Xiao-Ming Jiang, Guanchao Zheng, Hui-Ling Qiu, Aiguo Sha, Chonggang Wang, Jianzhi Ren, Zhenghong Zuo

PubMed

2014

褐菖鲉肝HSC70基因的环介导等温扩增技术的建立及在石油污染剂量效应研究中的应用

莫正平,陈荣,黄火清,左正宏

《生态毒理学报》

2014

Aroclor 1254 causes atrophy of exocrine pancreas in mice and the mechanism involved

Moudan Lin, Tian Wu, Lingbin Sun, Jackie Jin Lin, Zhenghong Zuo, Chonggang Wang

Environmental Toxicology

2014

Toxicogenomic analysis in the combined effect of tributyltin and benzo[a]pyrene on the development of zebrafish embryos

Lixing Huang, Zhenghong Zuo, Youyu Zhang, Chonggang Wang

Aquatic Toxicology

2014

Modulation of the DNA repair system and ATR-p53 mediated apoptosis is relevant for tributyltin-induced genotoxic effects in human hepatoma G2 cells

Bowen Li, Lingbin Sun, Jiali Cai, Chonggang Wang, Mengmeng Wang, Huiling Qiu, Zhenghong Zuo

Journal of Environmental Sciences

2014

Levels of Heavy Metals and Trace Elements in Umbilical Cord Blood and the Risk of Adverse Pregnancy Outcomes: a Population-Based Study

Guanchao Zheng, Hongxiu Zhong, Zhizhun Guo, Zhuangchu Wu, Huaiqing Zhang, Chonggang Wang, Yulin Zhou, Zhenghong Zuo

Biological Trace Element Research

2014

High mobility group Box-1 inhibits cancer cell motility and metastasis by suppressing activation of transcription factor CREB and nWASP expression

Zhenghong Zuo, Xun Che, Yulei Wang, Bowen Li, Jingxia Li, Wei Hao Dai, Charles P. Lin, Chuanshu Huang

Oncotarget

2014

Exposure to low dose benzo[a]pyrene during early life stages causes symptoms similar to cardiac hypertrophy in adult zebrafish

Lixing Huang, Dongxu Gao, Youyu Zhang, Chonggang Wang, Zhenghong Zuo

Journal of Hazardous Materials

2014

Use of toxicogenomics to predict the potential toxic effect of Benzo(a)pyrene on zebrafish embryos: Ocular developmental toxicity

Lixing Huang, Zhenghong Zuo, Youyu Zhang, Meifang Wu, Jackie Jin Lin, Chonggang Wang

Chemosphere

2014

Chronic Exposure to Tributyltin Chloride Induces Pancreatic Islet Cell Apoptosis and Disrupts Glucose Homeostasis in Male Mice

Zhenghong Zuo, Tian Wu, Moudan Lin, Shiqi Zhang, Feihuan Yan, Zhibin Yang, Yuanchuan Wang, Chonggang Wang

Environmental Science & Technology

2013

Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling

Youyu Zhang, Lixing Huang, Zhenghong Zuo, Yixin Chen, Chonggang Wang

Aquatic Toxicology

2013

Phenanthrene causes ocular developmental toxicity in zebrafish embryos and the possible mechanisms involved

Lixing Huang, Chonggang Wang, Youyu Zhang, Meifang Wu, Zhenghong Zuo

Journal of Hazardous Materials

2013

Phenanthrene exposure produces cardiac defects during embryo development of zebrafish (Danio rerio) through activation of MMP-9

Youyu Zhang, Lixing Huang, Chonggang Wang, Dongxu Gao, Zhenghong Zuo

Chemosphere

2013

Sex-different effects of tributyltin on brain aromatase, estrogen receptor and retinoid X receptor gene expression in rockfish (Sebastiscus marmoratus)

Jiliang Zhang, Zhenghong Zuo, Wenwen Zhu, Ping Sun, Chonggang Wang

Marine Environmental Research

2013

Cloning, expression and identification of two glutathione S-transferase isoenzymes from Perna viridis

Zhenzhen Li, Rong Chen, Zhenghong Zuo, Zhengping Mo, Ang Yu

Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology

2013

A Novel Effect of Polychlorinated Biphenyls: Impairment of the Tight Junctions in the Mouse Epididymis

Jiali Cai, Chonggang Wang, Lixing Huang, Meng Chen, Zhenghong Zuo

Toxicological Sciences

2012

Transcriptome Analysis of Male and Female Sebastiscus marmoratus

Lingbin Sun, Chonggang Wang, Lixing Huang, Meifang Wu, Zhenghong Zuo

PLoS ONE

2012

Tributyltin exposure causes lipotoxicity responses in the ovaries of rockfish, Sebastiscus marmoratus

Jiliang Zhang, Zhenghong Zuo, Jianli Xiong, Ping Sun, Yixin Chen, Chonggang Wang

Chemosphere

2012

Chronic exposure to paclobutrazol causes hepatic steatosis in male rockfish Sebastiscus marmoratus and the mechanism involved

Lingbin Sun, Jinshou Li, Zhenghong Zuo, Meng Chen, Chonggang Wang

Aquatic Toxicology

2012

Effects of Paclobutrazol Exposure on Antioxidant Defense System in Sebastiscus marmoratus

Jinshou Li, Lingbin Sun, Zhenghong Zuo, Meng Chen, Chonggang Wang

Bulletin of Environmental Contamination and Toxicology

2012

Pyrene exposure influences the thyroid development of Sebastiscus marmoratus embryos

Chengyong He, Zhenghong Zuo, Xiao Shi, Lingbin Sun, Chonggang Wang

Aquatic Toxicology

2012

Exposure to paclobutrazol disrupts spermatogenesis in male Sebastiscus marmoratus

Jinshou Li, Lingbin Sun, Zhenghong Zuo, Meng Chen, Hong Geng, Chonggang Wang

Aquatic Toxicology

2012

Exposure to tributyltin and triphenyltin induces DNA damage and alters nucleotide excision repair gene transcription in Sebastiscus marmoratus liver

Zhenghong Zuo, Chonggang Wang, Meifang Wu, Yuqing Wang, Yixin Chen

Aquatic Toxicology

2012

Exposure of Sebastiscus marmoratus embryos to pyrene results in neurodevelopmental defects and disturbs related mechanisms

Chengyong He, Chonggang Wang, Bowen Li, Meifang Wu, Hong Geng, Yixin Chen, Zhenghong Zuo

Aquatic Toxicology

2012

Low-level pyrene exposure causes cardiac toxicity in zebrafish (Danio rerio) embryos

Youyu Zhang, Chonggang Wang, Lixing Huang, Rong Chen, Yixin Chen, Zhenghong Zuo

Aquatic Toxicology

2012

Seminal Plasma Metals Concentration with Respect to Semen Quality

Ping Li, Yuanfu Zhong, Xiaoming Jiang, Chonggang Wang, Zhenghong Zuo, Aiguo Sha

Biological Trace Element Research

2012

Pyrene exposure influences the craniofacial cartilage development of Sebastiscus marmoratus embryos

Xiao Shi, Chengyong He, Zhenghong Zuo, Ruixia Li, Donglei Chen, Rong Chen, Chonggang Wang

Marine Environmental Research

2012

Embryonic exposure to benzo(a)pyrene influences neural development and function in rockfish (Sebastiscus marmoratus)

Chengyong He, Chonggang Wang, Yulin Zhou, Jian Li, Zhenghong Zuo

NeuroToxicology

2012

Tributyltin exposure results in craniofacial cartilage defects in rockfish (Sebastiscus marmoratus) embryos

Jiliang Zhang, Zhenghong Zuo, Ping Sun, Hongwei Wang, Ang Yu, Chonggang Wang

Marine Environmental Research

2012

Hexavalent Chromium Cr(VI) Up-Regulates COX-2 Expression through an NFκB/c-Jun/AP-1–Dependent Pathway

Zhenghong Zuo, Tongjian Cai, Jingxia Li, Dongyun Zhang, Yonghui Yu, Chuanshu Huang

Environmental Health Perspectives

2011

Benzo[a]pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos

Lixing Huang, Chonggang Wang, Youyu Zhang, Jian Li, Yuanfu Zhong, Yulin Zhou, Yixin Chen, Zhenghong Zuo

Chemosphere

2011

Chronic Exposure to Phenanthrene Influences the Spermatogenesis of Male Sebastiscus marmoratus: U-Shaped Effects and the Reason for Them

Lingbin Sun, Zhenghong Zuo, Hongmin Luo, Meng Chen, Yuanfu Zhong, Yixin Chen, Chonggan Wang

Environmental Science & Technology

2011

Disruption of spermatogenesis and differential regulation of testicular estrogen receptor expression in mice after polychlorinated biphenyl exposure

Jiali Cai, Chonggang Wang, Tian Bao Wu, João Manuel Lopes Moreno, Yuanfu Zhong, Xin Huang, Yixin Chen, Zhenghong Zuo

Toxicology

2011

Influence of triphenyltin exposure on the hypothalamus–pituitary–gonad axis in male Sebastiscus marmoratus

Lingbin Sun, Jiliang Zhang, Zhenghong Zuo, Yixin Chen, Xinhong Wang, Xin Huang, Chonggang Wang

Aquatic Toxicology

2010

Effects of benzo(a)pyrene on the skeletal development of Sebastiscus marmoratus embryos and the molecular mechanism involved

Chengyong He, Zhenghong Zuo, Xiao Shi, Ruixia Li, Donglei Chen, Xin Huang, Yixin Chen, Chonggang Wang

Aquatic Toxicology

2010

Inhibition by polycyclic aromatic hydrocarbons of ATPase activities in Sebastiscus marmoratus larvae:Relationship with the development of early life stages

Ruixia Li, Zhenghong Zuo, Donglei Chen, Chengyong He, Rong Chen, Yixin Chen, Chonggang Wang

Marine Environmental Research

2010

Tributyltin chloride results in dorsal curvature in embryo development of Sebastiscus marmoratus via apoptosis pathway

Jiliang Zhang, Zhenghong Zuo, Yuqing Wang, Ang Yu, Yixin Chen, Chonggang Wang

Chemosphere

2010

Identification of differentially expressed genes in the brain of Sebastiscus marmoratus in response to tributyltin exposure

Bowen Li, Chonggang Wang, Ang Yu, Yixin Chen, Zhenghong Zuo

Aquatic Toxicology

2009

我国几种野鸭和家鸭遗传多样性的SSR分析

鄢绯寰,左正宏,吕良炬,陈美,陈奕欣

《厦门大学学报(自然科学版)》

2009

Tissue-specific and embryonic expression of the retinoid X receptors in Sebastiscus marmoratus.

Cheng-Yong He, Chonggang Wang, Bo-Wen Li, F. Xie, Yi-Xin Chen, Zhenghong Zuo

Comparative Biochemistry and Physiology Part B Comparative Biochemistry

2009

Tributyltin causes obesity and hepatic steatosis in male mice

Zhenghong Zuo, Shuzhen Chen, Tian Bao Wu, Jiliang Zhang, Ying Su, Yixin Chen, Chonggang Wang

Environmental Toxicology

2009

Apoptotic and Necrotic Action Mechanisms of Trimethyltin in Human Hepatoma G2 (HepG2) Cells

Jiali Cai, Mengmeng Wang, Bowen Li, Chonggang Wang, Yixin Chen, Zhenghong Zuo

Chemical Research in Toxicology

2009

DNA hypomethylation induced by tributyltin, triphenyltin, and a mixture of these in Sebastiscus marmoratus liver

Yuqing Wang, Chonggang Wang, Jiliang Zhang, Yixin Chen, Zhenghong Zuo

Aquatic Toxicology

2009

Inhibition of thyroidal status related to depression of testicular development in Sebastiscus marmoratus exposed to tributyltin

Jiliang Zhang, Zhenghong Zuo, Chengyong He, Di Wu, Yixin Chen, Chonggang Wang

Aquatic Toxicology

2009

Effect of tributyltin on testicular development in Sebastiscus marmoratus and the mechanism involved

Jiliang Zhang, Zhenghong Zuo, Chengyong He, Jiali Cai, Yuqing Wang, Yixin Chen, Chonggang Wang

Environmental Toxicology and Chemistry

2009

Effects of tributyltin on epididymal function and sperm maturation in mice

Feihuan Yan, Yufang Chen, Zhenghong Zuo, Yixin Chen, Zeng‐Ming Yang, Chonggang Wang

Environmental Toxicology and Pharmacology

2009

Acute administration of tributyltin and trimethyltin modulate glutamate and N-methyl-d-aspartate receptor signaling pathway in Sebastiscus marmoratus

Zhenghong Zuo, Jiali Cai, Xinli Wang, Bowen Li, Chonggang Wang, Yixin Chen

Aquatic Toxicology

2008

基因功能研究方法的新进展

杜玉梅,左正宏

《生命科学》

2008

不同培养条件对坛紫菜叶状体体细胞发育分化影响的研究

赵扬,蔡嘉力,左正宏,吕良炬,陈奕欣

《应用海洋学学报》

2008

三丁基锡(TBT)对褐菖鲉肝脏抗氧化系统的影响

赵扬,王云,左正宏,陈奕欣,王重刚

《厦门大学学报(自然科学版)》

2008

Differential gene expression in the brain of Sebastiscus marmoratus in response to exposure to polychlorinated biphenyls (PCBs)

Bowen Li, Chonggang Wang, Kai Ye, Ang Yu, Yixin Chen, Zhenghong Zuo

Marine Environmental Research

2008

Acute trimethyltin exposure induces oxidative stress response and neuronal apoptosis in Sebastiscus marmoratus

Xinli Wang, Jiali Cai, Jiliang Zhang, Chonggang Wang, Ang Yu, Yixin Chen, Zhenghong Zuo

Aquatic Toxicology

2008

Tributyltin exposure causes brain damage in Sebastiscus marmoratus

Jiliang Zhang, Zhenghong Zuo, Rong Chen, Yixin Chen, Chonggang Wang

Chemosphere

2008

Reduction of spermatogenesis in mice after tributyltin administration

Yufang Chen, Zhenghong Zuo, Shuzhen Chen, Feihuan Yan, Yixin Chen, Zeng‐Ming Yang, Chonggang Wang

Toxicology

2008

The concentration-dependent induction of cell death by trimethyltin chloride in rat liver epithelial IAR20 cells

Mengmeng Wang, Bowen Li, Chonggang Wang, Yixin Chen, Zhenghong Zuo

Toxicology in Vitro

2008

Exogenous leptin promotes the recovery of regressed ovary in fasted ducks

Yueqiang Song, Chonggang Wang, Cheng Wang, Liangju Lv, Yixin Chen, Zhenghong Zuo

Animal Reproduction Science

2008

Relation of hepatic EROD activity and cytochrome P4501A level in Sebastiscus marmoratus exposed to benzo[a]pyrene

Yun Wang, Ronghui Zheng, Zhenghong Zuo, Yixin Chen, Chonggang Wang

Journal of Environmental Sciences

2007

瘦素在禽类中的研究进展

宋岳强,左正宏,王诚,陈奕欣

《动物学杂志》

2007

坛紫菜种质资源遗传多样性的AFLP分析

陈奕欣,左正宏,陈骁,王重刚,吕良炬

《厦门大学学报(自然科学版)》

2007

三丁基锡对褐菖鲉肝脏DNA损伤的研究

王云,魏炜,左正宏,陈奕欣,赵扬,王重刚

《厦门大学学报(自然科学版)》

2007

坛紫菜别藻蓝蛋白β亚基的表达及鉴定

杨听林,左正宏,蔡嘉力,王重刚,陈奕欣

《厦门大学学报(自然科学版)》

2007

三丁基锡对褐菖鲉(Sebastiscus marmoratus)体内苯并(α)芘代谢的影响

郑榕辉,赵扬,陈奕欣,左正宏,王重刚

《海洋学报》

2007

0#柴油水溶性成分暴露对雌性褐菖鲉血浆卵黄蛋白原水平的影响

刘睿智,李瑞霞,左正宏,陈奕欣,王重刚

《厦门大学学报(自然科学版)》

2007

Increasing transient expression of CAT gene in Porphyra haitanensis by Matrix attachment regions and 18S rDNA targeted homologous recombination

Zhenghong Zuo, Bowen Li, Chonggang Wang, Jiali Cai, Yixin Chen

Aquaculture Research

2007

Effect of tributyltin on the development of ovary in female cuvier (Sebastiscus marmoratus)

Jiliang Zhang, Zhenghong Zuo, Yixin Chen, Yang Zhao, Shuai Hu, Chonggang Wang

Aquatic Toxicology

2007

Antioxidant responses to benzo[a]pyrene, tributyltin and their mixture in the spleen of Sebasticus marmoratus

Yuqiong Wu, Chonggang Wang, Yun WANG, Yang Zhao, Yixin Chen, Zhenghong Zuo

Journal of Environmental Sciences

2006

坛紫菜别藻蓝蛋白α亚基基因的原核表达与鉴定

左正宏,李博文,聂鑫怡,王重刚,陈奕欣

《水生生物学报》

2006

坛紫菜突变体的品质性状分析

董宏坡,左正宏,陈奕欣

《广东石油化工学院学报》

2006

金定鸭和南安鸭肉用性状的比较

陈德猛,陈美,左正宏,陈奕欣

《厦门大学学报(自然科学版)》

2006

小鼠OB基因的克隆及在大肠杆菌中的高效表达

宋岳强,左正宏,王诚,吕良炬,陈奕欣

《厦门大学学报(自然科学版)》

2006

家蚕精子介导报告基因gfp和egfp转移技术的研究

左正宏,吴春旭,桂慕燕,陈元霖,洪满贤

《厦门大学学报(自然科学版)》

2006

MNNG(N-甲基-N′-硝基-N-亚硝基胍)诱变坛紫菜原生质体的初步研究

李勇斌,左正宏,李博文,江雨,陈奕欣

《厦门大学学报(自然科学版)》

2006

四种启动子调控RFP报告基因在家蚕细胞(Bm-e-HNU5)内的瞬时表达

王云,叶向群,吴亦亮,桂慕燕,左正宏

《昆虫学报》

2006

60Co-γ诱变坛紫菜的海区栽培选育及品质性状初步分析

黄秋,左正宏,李勇斌,李博文,陈奕欣

《应用海洋学学报》

2006

三丁基锡对文蛤消化腺脂质过氧化及抗氧化酶活性的影响

黄周英,陈奕欣,左正宏,赵扬,王重刚

《厦门大学学报(自然科学版)》

2006

坛紫菜中别藻蓝蛋白的纯化及洗脱组分光谱研究

董宏坡,左正宏,陈奕欣

《植物科学学报》

2006

Isolation and characterization of microsatellite loci from a commercial cultivar of Porphyra haitanensis

Zhenghong Zuo, Chonggang Wang, XIAOHUA CAO, YING SU, LIJING LIAO, Yixin Chen

Molecular Ecology Notes

2006

AFLP analysis of genetic diversity and relationship among some Chinese domestic ducks and wild ducks

Feihuan Yan, Zhenghong Zuo, Mei Chen, Yueqiang Song, Liangju Lü, Yixin Chen

Frontiers in Biology

2005

坛紫菜别藻蓝蛋白α,β亚基基因的克隆和序列分析

左正宏,邓元告,陈奕欣,赵扬,郑微云

《海洋学报》

2005

60Co-γ辐照对坛紫菜原生质体诱变的研究

姚继承,王诚,左正宏,林芳,陈奕欣

《海洋科学》

2005

三丁基锡对文蛤外套膜代谢酶活性的影响

黄周英,陈奕欣,左正宏,赵扬,陈美,王重刚

《应用海洋学学报》

2005

几种紫菜种质资源遗传多样性的RAPD分析

陈骁,左正宏,姚继承,陈奕欣

《海洋科学》

2005

Effect of Tributyltin, Benzo[a]pyrene, and Their Mixture on the Hepatic Monooxygenase System in Sebastiscus marmoratus

C. G. Wang, Ronghui Zheng, Xiaojun Ding, Zhenghong Zuo, Yang Zhao, Yanxia Chen

Bulletin of Environmental Contamination and Toxicology

2005

Effect of Tributyltin at Environmentally Relevant Doses on Levels of Sex Hormones in Female Clams Meretrix meretrix

C. G. Wang, Z. Y. Huang, Yanxia Chen, Yang Zhao, Zhenghong Zuo

Bulletin of Environmental Contamination and Toxicology

2005

Effects of tributyltin, benzo[a]pyrene, and their mixture on antioxidant defense systems in Sebastiscus marmoratus

Chonggang Wang, Yang Zhao, Ronghui Zheng, Xin Ding, Wei Wei, Zhenghong Zuo, Yixin Chen

Ecotoxicology and Environmental Safety

2005

Effect of tributyltin, benzo(a)pyrene and their mixture exposure on the sex hormone levels in gonads of cuvier (Sebastiscus marmoratus)

Ronghui Zheng, Chonggang Wang, Yang Zhao, Zhenghong Zuo, Yixin Chen

Environmental Toxicology and Pharmacology

2005

Antioxidant responses in Meretrix meretrix exposed to environmentally relevant doses of tributyltin

Zhouying Huang, Yixin Chen, Yang Zhao, Zhenghong Zuo, Mei Chen, Chonggang Wang

Environmental Toxicology and Pharmacology

2004

坛紫菜叶状体体细胞对抗生素敏感性的研究

赵扬,李秀,左正宏,王诚,王重刚,陈奕欣

《应用海洋学学报》

2004

中华盒形藻有性生殖过程中的光效应和光受体

杨听林,左正宏,林均民

《海洋科学》

2004

野生及家养动物胰吸虫病原DNA多态性的比较研究

叶向群,左正宏,杨文川,彭文峰

《中国人兽共患病学报》

2003

应用精子载体法导入外源DNA影响家蚕遗传性的研究

桂慕燕,叶向群,左正宏,吴春旭,陈元霖,羿红,朱明贞,林友照

《蚕业科学》

2001

五种绢丝昆虫随机扩增多态性DNA分析

桂慕燕,左正宏,陈元霖

《遗传》

2001

RAPD分析在绢丝昆虫亲缘关系研究中的应用Ⅱ.柞蚕品种间的遗传差异

桂慕燕,左正宏,王学民,陈元霖

《遗传》

1999

玉米α_微管蛋白分子生物学研究进展

许莉,郑文竹,左正宏,周涵韬,许玉德

《植物学报》

1999

蚕丝昆虫分子系统学与物种分子标记研究初报

桂慕燕,左正宏,陈元霖,王学民

《云南大学学报(自然科学版)》

1999

我国部分家鸭品种遗传多样性及与野鸭亲缘关系的探讨

陈奕欣,左正宏,陈小麟,吕良炬,赵扬

《云南大学学报(自然科学版)》

会议论文

2023

肠道菌群在黑磷量子点诱导小鼠肾脏免疫损伤中的机制研究

阮锋凯,曾洁,刘常乾,尹涵颖,左正宏,何承勇

《中国毒理学会第十次全国毒理学大会》

2023

RNA m 6 A修饰差异调控纳米材料诱导的肺损伤

阮锋凯,曾洁,尹涵颖,刘常乾,左正宏,何承勇

《中国毒理学会第十次全国毒理学大会》

2023

BPQDs诱导的体内外肺损伤效应及其机制研究

曾洁,阮锋凯,吴鸣涛,许佳滢,左正宏,何承勇

《中国毒理学会第十次全国毒理学大会》

2023

多氯联苯138哺乳期暴露对小鼠子宫发育的影响及机制研究

阮金鹏,马文溯,肖敏,唐晨,何承勇,左正宏

《中国毒理学会第十次全国毒理学大会》

2023

三丁基锡诱导多囊卵巢综合征对雄性后代神经发育的影响及其机制

蔡浩星,陈明月,高洋,何承勇,左正宏

《中国毒理学会第十次全国毒理学大会论文集》

2015

Benzo[a]pyrene exposure during the embryo stage causes Parkinson's disease-like syndrome in adult zebrafish(Danio rerio)

Dongxu Gao, Chonggang Wang, Yuanchuan Wang, Hong Du, Zhenghong Zuo

《2015毒性测试替代方法与转化毒理学(国际)学术研讨会会议论文集》

2014

环境水平的PAHs暴露引发心脏毒性及其分子机制

黄力行,王重刚,章幼玉,杨志兵,张诗琦,左正宏

《第八届全国分析毒理学大会暨中国毒理学会分析毒理专业委员会第五届会员代表大会论文摘要集》

2014

利用基因组学技术分析多环芳烃对斑马鱼的发育毒性效应和机制

黄力行,左正宏,章幼玉,王重刚

《第八届全国分析毒理学大会暨中国毒理学会分析毒理专业委员会第五届会员代表大会》

2006

坛紫菜别藻蓝蛋白的表达、纯化及生物学活性的分析

左正宏,杨听林,王礞礞,蔡嘉力,陈奕欣

《第十次中国生物物理学术大会论文摘要集》

2006

外源植物激素对坛紫菜生长发育的影响及蛋白组学分析

左正宏,江雨,陈瑜芳,王重刚,陈奕欣

《第十次中国生物物理学术大会》

预印本

2026

Pterostilbene ameliorates tributyltin-induced uterine injury by activating Estrogen Receptor-α and the PI3K/ Akt signaling pathway

Fanzheng Xue, Zizhen Wang, Chen Tang, Pengtao Chen, Fucong Zhang, Chunyan Yang, Chengyong He, Zhenghong Zuo

SSRN Electronic Journal

2025

CEP76 Mutation Causes Male Infertility by Disrupting Histone-to-Protamine Transition During Sperm Chromatin Condensation

Fucong Zhang, Wensheng Liu, Suhua Jiang, Jingyi Wang, Zewei Long, Zhiyuan Chen, Shu Li, Zhineng Fu, Xianhan Qin, Hao Yuan, Mengnan Jiang, Wei Wang, Chunyan Yang, Yu Jiang, Chuan‐Qi Zhong, Xun Lan, Yan-Wei Sha, Zhenghong Zuo, Chengyong He

SSRN Electronic Journal

2021

Mepanipyrim and cyprodinil induce divergent temporal patterns of AhR-mediated responses in zebrafish (Danio rerio) embryos and larvae

Chao Shen, Chen Ying Tang, Kongyang Zhu, Chengyong He, Chunyan Yang, Zhenghong Zuo

Research Square

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