百晓学者学者目录

张亚军

副教授、教授,西北大学

精选作品

期刊论文

2025

Affinity-Driven Two-Step Immobilization of Endogenous Natural GABAA Receptor to Quantify Drug–Protein Analysis with Enhanced Sensitivity and Accuracy

Xue Zhao, Xue Zhao, Mingxuan Kang, Sidi Cun, Ruoxue Bai, Mei Lv, Tongtong Li, Yajun Zhang, Xinfeng Zhao, Xinfeng Zhao

Analytical Chemistry

2025

Integrating click chemistry into protein expression for efficient preparation of immobilized protein bio-surface with enhanced stability and reproducibility in affinity chromatography

Xue Zhao, Yunshan Wang, Jiatai Yin, Sidi Cun, Yuanyuan Ou, Qian Li, Xinfeng Zhao, Yajun Zhang

Analytica Chimica Acta

2025

Transcriptomic analysis and experiment to verify the mechanism of Xiaoyao san in the treatment of irritable bowel syndrome with depression

Jiaoyan Yu, Xi Li, Yantao Sun, Ludan Wang, Yajun Zhang

Journal of Ethnopharmacology

2025

A strategy for selective screening of dual-target bioactive compounds against hypertrophic scar through inhibiting angiotensin II type 1 receptor while stimulating type 2 receptor from Chinese herbs

Lejing Qu, Meizhi Jiao, Zilong Zhang, Yuanyuan Ou, Xue Zhao, Yajun Zhang, Xinfeng Zhao

Chinese Medicine

2024

秦药研究现状及展望

范香立,窦红莉,张亚军

《中华中医药杂志》

2024

Protective effects of bioactive components targeting β2-adrenergic receptors and muscarinic-3 acetylcholine receptor in Zhisou San on ovalbumin-induced allergic asthma

Fengwu Li, Na Zhou, Jing-Jing Li, Yajun Zhang, Xue Zhi Zhao

Journal of Asian Natural Products Research

2024

Can the heptapeptide ASSIVSF of the β2-adrenoceptor recognize ephedrine and pseudoephedrine epimers in a complex system?

Jiatai Yin, Yiheng Gou, Yiheng Wang, Qingyuan Ma, Rui Wang, Jing Yu, Yajun Zhang, Jing Wang, Qian Li, Xinfeng Zhao

Journal of Chromatography A

2024

A chromatographic method for pursuing potential GPCR ligands with the capacity to characterize their intrinsic activities of regulating downstream signaling pathway

Ting Li, Ting Li, Xinxin Zheng, Yuanyuan Ou, Yuanyuan Ou, Sai Qiao, Xue Zhao, Xue Zhao, Yajun Zhang, Xinfeng Zhao, Xinfeng Zhao, Qianli Ma

Chinese Chemical Letters

2023

Screening and evaluation of the hit compound from a DNA-encoded library derived from natural products based on immobilized endothelin receptor A

Yajun Zhang, Li Lin, Sai Qiao, Xue Zhao, Ting Li, Qi Liang

International Journal of Biological Macromolecules

2023

Affinity Chromatographic Method for Determining Drug–Protein Interaction with Enhanced Speed Than Typical Frontal Analysis

Yuanyuan Ou, Sai Qiao, Ting Li, Xinxin Zheng, Xue Zhao, Lejing Qu, Xinfeng Zhao, Yajun Zhang

Langmuir

2023

Immobilization of M3 Muscarinic Receptor to Rapidly Analyze Drug—Protein Interactions and Bioactive Components in a Natural Plant

Hushuai Fan, Xiaomin Huang, Ziru Zhang, Ting Wang, Ludan Wang, Yajun Zhang

International Journal of Molecular Sciences

2022

Early potential evaluation of lead compounds from a DNA-encoded library by the determination of their thermodynamics through a chromatographic method based on immobilized β2-adrenoceptor

Qi Liang, Bowen Shi, Qingqing Yao, Taotao Wang, Xu Ji, Yajun Zhang, Jing Wang, Xinfeng Zhao

Bioorganic & Medicinal Chemistry

2022

Revealing the Antiepileptic Effect of α‑Asaronol on Pentylenetetrazole-Induced Seizure Rats Using NMR-Based Metabolomics

Xue Zhao, Lihong Liang, Ru Xu, Peixuan Cheng, Pu Jia, Yajun Bai, Yajun Zhang, Xinfeng Zhao, Xiaohui Zheng, Chaoni Xiao

ACS Omega

2022

Site-selective covalently immobilized alpha 1A adrenergic receptor for thermodynamic and extra-thermodynamic study of four ligands binding to the receptor by chromatographic methods

Xinyi Yuan, Aerduosi Shayiranbieke, Xu Ru, Hongmei Jiang, Yushan Yang, Yajun Zhang, Guowei Yin, Xinfeng Zhao

Journal of Chromatography A

2020

Covalent Inhibitor-Based One-Step Method for Endothelin Receptor A Immobilization: from Ligand Recognition to Lead Identification

Xinfeng Zhao, Yahui Jin, Xinyi Yuan, Zhaoling Hou, Ziyue Chen, Xiaoying Fu, Qian Li, Jing Wang, Yajun Zhang

Analytical Chemistry

2019

探讨大黄不同炮制品与水蛭联合用药对大鼠糖尿病肾病肾脏的保护作用

薛滋平,张志芳,李琛,曹瑞岗,张亚军

《时珍国医国药》

2019

中药骨炎方治疗胫骨慢性骨髓炎的作用机制

黄楠,齐明,张军,武永刚,李金宸,张亚军

《药学前沿》

2019

基于HPLC-Q-TOF/MS和GC/MS的香丹注射液化学成分分析

高添,杨凌鉴,盛鑫康,师白梅,韩焰青,贾璞,张亚军,王世祥,于洁,郑晓晖

《中成药》

2019

Polygala tenuifolia-Acori tatarinowii herbal pair as an inspiration for substituted cinnamic α-asaronol esters: Design, synthesis, anticonvulsant activity, and inhibition of lactate dehydrogenase study

Yajun Bai, Xirui He, Yujun Bai, Ying Sun, Zefeng Zhao, Xufei Chen, Bin Li, Jing Xie, Yang Li, Pu Jia, Xue Zheng Meng, Ye Zhao, Yanrui Ding, Chaoni Xiao, Shixiang Wang, Jie Yu, Sha Liao, Yajun Zhang, Zhiling Zhu, Qiang Zhang, Yuhui Zhao, Fanggang Qin, Yi Zhang, Xiaoyang Wei, Min Zeng, Jing Liang, Ye Cuan, Guangzhi Shan, Tai-Ping Fan, Biao Wu, Xiaohui Zheng

European Journal of Medicinal Chemistry

2019

Characterization of the heterogeneous adsorption of three drugs on immobilized bovine serum albumin by adsorption energy distribution

Huanmei Sun, Jiajun Liu, Yifei Li, Jing Wang, Yajun Zhang

Journal of Chromatography B

2019

Site-Specific Immobilization of β2-AR Using O6-Benzylguanine Derivative-Functionalized Supporter for High-Throughput Receptor-Targeting Lead Discovery

Jing Wang, Yuxin Wang, Jiajun Liu, Qian Li, Guowei Yin, Yajun Zhang, Chaoni Xiao, Tai‐Ping Fan, Xinfeng Zhao, Xiaohui Zheng

Analytical Chemistry

2018

Rapid screening and identification of bioactive compounds specifically binding to beta 2-adrenoceptor from San-ao decoction using affinity magnetic fine particles coupled with high-performance liquid chromatography–mass spectrometry

Fuhuan Fei, Huanmei Sun, Xixi Cheng, Jiajun Liu, Jing Wang, Qian Li, Yajun Zhang

Chinese Medicine

2018

Tanshinol borneol ester on nanostructured lipid carriers has longer brain and systemic effector retention and better antioxidant activity in vivo

Xinyi Yuan, Fuhuan Fei, Huanmei Sun, Chaoni Xiao, Xinfeng Zhao, Yajun Zhang, Xiaohui Zheng

International Journal of Nanomedicine

2017

[Optimization of preparation procedures of tanshinone-ⅡA /β-cyclodextrin inclusion complex and dissolution study of tanshinone-ⅡA in vitro].

Ni Wu, Jie Yu, Xia Zhang, Min Zeng, Yajun Zhang, Xiaohui Zheng

PubMed

2017

One-step methodology for the direct covalent capture of GPCRs from complex matrices onto solid surfaces based on the bioorthogonal reaction between haloalkane dehalogenase and chloroalkanes

Kaizhu Zeng, Qian Li, Jing Wang, Guowei Yin, Yajun Zhang, Chaoni Xiao, Tai‐Ping Fan, Xinfeng Zhao, Xiaohui Zheng

Chemical Science

2017

Anticonvulsant activities of α-asaronol (( E )-3′-hydroxyasarone), an active constituent derived from α-asarone

Xirui He, Yajun Bai, Min Zeng, Zefeng Zhao, Qiang Zhang, Ning Xu, Fanggang Qin, Xiaoyang Wei, Meimei Zhao, Ni Wu, Zehua Li, Yajun Zhang, Tai-Ping Fan, Xiaohui Zheng

Pharmacological Reports

2017

A fast affinity extraction methodology for rapid screening of bioactive compounds specifically binding to beta2-adrenergic receptor from Xie-Bai-San

Zhenyu Sun, Jing Wang, Qian Li, Meimei Zhao, Yajun Zhang, Xunyu Xiong, Xinfeng Zhao, Xiaohui Zheng

Medicinal Chemistry Research

2017

Identification of bioactive compounds in Shaoyao‐Gancao decoction using β2‐adrenoceptor affinity chromatography

Zehua Li, Haiyang Gao, LI Jiang-ying, Yajun Zhang

Journal of Separation Science

2016

基于HPLC-Q-TOF-MS/MS的广枣果肉化学成分分析

杨璐萌,杨凌鉴,贾璞,兰薇,张亚军,王世祥,张鹏,郑晓晖

《海军军医大学学报》

2016

Identifying the antiasthmatic target of doxofylline using immobilized β 2 -adrenoceptor based high-performance affinity chromatography and site-directed molecular docking

Yajun Zhang, Kaizhu Zeng, Jing Wang, Haiyang Gao, Yefei Nan, Xiaohui Zheng

Journal of Molecular Recognition

2016

Local and traditional uses, phytochemistry, and pharmacology of Sophora japonica L.: A review

Xirui He, Yajun Bai, Zefeng Zhao, Xiaoxiao Wang, Jiacheng Fang, Linhong Huang, Min Zeng, Qiang Zhang, Yajun Zhang, Xiaohui Zheng

Journal of Ethnopharmacology

2015

丹参素异丙酯经鼻吸收的影响因素

韩姣姣,曲秦,吕卓,王玥月,郑晓晖,张亚军

《中成药》

2015

β-(3,4-二羟基苯基)-α-羟基丙酸异丙酯滴丸制剂处方优化

韩姣姣,曲秦,王玥月,郑晓晖,张亚军

《中国医院药学杂志》

2015

The metabonomic study of Shaoyao-Gancao decoction in a rat model of acute bronchial asthma by 1 H NMR

Haiyang Gao, Zhe Sun, Chaoni Xiao, Xiaohui Zheng, Yajun Zhang

Analytical Methods

2015

Comparison of zonal elution and nonlinear chromatography in determination of the interaction between seven drugs and immobilised β2-adrenoceptor

Qian Li, Jing Wang, Yuqing Zheng, Lingjian Yang, Yajun Zhang, Liujiao Bian, Jianbin Zheng, Zijian Li, Xinfeng Zhao, Youyi Zhang

Journal of Chromatography A

2015

Binding interactions between prazosin and α 1A -adrenoceptor: investigation on the thermodynamic behaviors and the binding mechanism by high performance affinity chromatography

Jing Wang, Qian Li, Lingjian Yang, Yajun Zhang, Yajun Zhang, Jie Yu, Xinfeng Zhao, Jianbin Zheng, Youyi Zhang, Youyi Zhang, Xiaohui Zheng

Analytical Methods

2014

正交设计法优选跌打止痛巴布剂的基质处方

李江英,张亚军,刘超

《陕西中医》

2014

Revealing Metabolomic Variations in Cortex Moutan from Different Root Parts using HPLC–MS method

Chaoni Xiao, Man Wu, Yongyong Chen, Yajun Zhang, Xinfeng Zhao, Xiaohui Zheng

Phytochemical Analysis

2014

The structure‐dependent self‐association of five phenolic acids in aqueous solution

Chaoni Xiao, Man Wu, Yajun Zhang, Xinfeng Zhao, Jie Yu, Xiaohui Zheng

Magnetic Resonance in Chemistry

2014

Oriented immobilisation of histidine-tagged protein and its application in exploring interactions between ligands and proteins

Xinfeng Zhao, Qian Li, Chaoni Xiao, Yajun Zhang, Yajun Zhang, Liujiao Bian, Xiaohui Zheng, Xiaohui Zheng, Zijian Li, Youyi Zhang, Youyi Zhang, Tai‐Ping Fan

Analytical and Bioanalytical Chemistry

2014

Cold water forced swimming stress induced metabolic alterations in rats

Chaoni Xiao, Pu Jia, Man Wu, Yajun Zhang, Shixiang Wang, Xinfeng Zhao, Xiaohui Zheng

Analytical Methods

2013

家独行菜的化学成分研究

孙哲,白妮,肖超妮,赵晓旭,张亚军,郑晓晖

《中成药》

2013

在体皮肤微透析技术评价苦参碱传递体的透皮释药性能

张亚军,杨建宏,韩娇娇,戴贵东

《中草药》

2013

同时包载苦参碱和氧化苦参碱的传递体制备研究

王玥月,杨建宏,戴贵东,李江英,张亚军

《中成药》

2013

Targeted delivery of the RGD-labeled biodegradable polymersomes loaded with the hydrophilic drug oxymatrine on cultured hepatic stellate cells and liver fibrosis in rats

Jianhong Yang, Yanhui Hou, Gangjian Ji, Zhihua Song, Yanhua Liu, Guidong Dai, Yajun Zhang, Jianhai Chen

European Journal of Pharmaceutical Sciences

2013

Improved Process for Pilot-Scale Synthesis of Danshensu ((±)-DSS) and Its Enantiomer Derivatives

Yajun Bai, Qun-Zheng Zhang, Pu Jia, Lingjian Yang, Yuhong Sun, Yefei Nan, Shixiang Wang, Xue Zheng Meng, Yizhen Wu, Fanggang Qin, Zhe Sun, Xiaokang Gao, Pei Liu, Kai Luo, Yajun Zhang, Xinfeng Zhao, Chaoni Xiao, Sha Liao, Jianli Liu, Cuiling Wang, Jiacheng Fang, Xiaoxiao Wang, Jing Wang, Rong Gao, Xuexia An, Xunli Zhang, Xiaohui Zheng

Organic Process Research & Development

2012

交泰丸中肉桂对黄连小檗碱在大鼠体内药动学的影响

白妮,李江英,陈烨丹,郑晓晖,张亚军

《中成药》

2012

HPLC测定丹参素冰片酯脂肪乳注射液含量及有关物质

刘海静,王雨轩,李霞,张亚军,惠民权,郑晓晖

《药物分析杂志》

2011

双花连翘水凝胶的鉴别与含量测定

王小青,裴渭静,唐旭东,孟雪,张亚军,郑晓晖

《药物分析杂志》

2011

HPLC法测定活血胶囊中羟基红花黄色素A、柚皮苷

毛阿娟,王晓雯,王世祥,彭宁,张亚军,郑晓晖,刘勤社

《中成药》

2011

十字花科植物化学成分和药理作用研究概况

白妮,张亚军,王世祥,申旭霁,王倩,郑晓晖

《中药材》

2011

Isopropyl 3,4-dihydroxybenzoate

Xu-Ji Shen, Qun-Zheng Zhang, Shixiang Wang, Yajun Zhang, Xiaohui Zheng

Acta Crystallographica Section E Structure Reports Online

2010

高效液相色谱-二极管阵列-离子阱质谱法对红花水提物中有效成分群的定性分析

王晓雯,彭宁,张鹏,左燕,张亚军,赵新锋

《中国药业》

2010

溃结康结肠靶向微丸控释衣膜处方优化

张亚军,李江英,郑杭生

《中国医院药学杂志》

2010

丹参酮ⅡA自微乳制剂在大鼠体内血药浓度测定

张亚军,李江英,崔延堂

《中国现代应用药学》

2009

全缘千里光碱脂质体凝胶剂制备工艺的研究

郑杭生,张亚军,张彤,徐莲英

《中国药学杂志》

2009

流化床包衣法制备天麻效应组分缓释微丸的研究

洪燕龙,林晓,徐德生,冯怡,李峻松,张亚军

《中药材》

2009

溃结康结肠靶向微丸中黄芩苷在大鼠体内血药浓度测定

张亚军,郑杭生,李江英,徐莲英

《药物分析杂志》

2009

HPLC研究檀香对丹参素组织分布的影响

张前,唐一梅,王锐,王世祥,房敏峰,张亚军,郑晓晖

《中国中药杂志》

2009

Determination of Baicalin in Bikangbao Capsule by HPLC

Yajun Zhang

Journal of Pediatric Pharmacy

2008

溃结康微丸的制备和体外溶出度考察

张亚军,刘茵,李江英

《中国医院药学杂志》

2008

溃结康结肠靶向微丸中黄芩苷的体外释放度研究

李江英,张亚军,董力

《中成药》

2008

[Evaluation of targeting property for Kuikang colon targeted pellets].

Yajun Zhang, Jiang-Ying Li, XU Lian-ying

PubMed

2007

正交设计研究白芍的提取工艺

李江英,张亚军,董力

《陕西中医药大学学报》

2007

挤出滚圆法制备溃结康微丸及其性质

王巧玲,李爱婷,张亚军

《陕西中医》

2007

HPLC法同时测定溃结康微丸中芍药苷和黄芩苷的含量

张亚军,郑杭生,李江英,徐莲英

《药物分析杂志》

2007

全缘千里光碱脂质体包封率测定方法的研究

郑杭生,张亚军,徐真,徐莲英

《中国药学杂志》

2007

黄芩汤中黄芩苷在大鼠体内的药代动力学研究

李云,张亚军,李江英

《陕西中医》

2006

全缘千里光碱脂质体凝胶剂的HPLC测定

宋华,郑杭生,张亚军,熊阳,徐莲英

《中国医药工业杂志》

2006

HPD100大孔吸附树脂在白芍纯化工艺中的应用研究

张亚军,徐莲英

《中药材》

2003

天然药物及其有效成分降血糖作用机理的研究进展

张亚军,李江英

《西北药学杂志》

2003

注射用葛根素的质量标准研究

李江英,张亚军

《中成药》

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