白钢｜南开大学｜学者主页

2026

基于化学生物学的中药药性-药效关联机制研究策略

白钢，侯媛媛，姜民，高洁，张曼，刘文娟

《药学学报》

DOI

2026

基于深度学习与近红外光谱技术对海洋中药马刀的数智评价研究

王江涛，刘至全，庞晓凤，郝二伟，侯媛媛，侯小涛，白钢，邓家刚

《中草药》

2026

黎欣，梁沁沁，张冰月，夏中尚，白钢，杜正彩，郝二伟，邓家刚，侯小涛

《中国中药杂志》

2025

Chuanjing Cheng, Kaixin Liu, Jinling Zhang, Yanqi Han, Tiejun Zhang, Yuanyuan Hou, Gang Bai

Acta Pharmaceutica Sinica B

DOI

2023

王洁，闫孟琳，张曼，姜民，白钢

《药学学报》

2022

桂枝茯苓胶囊的溶出度测试及评价研究

黄照博，王龙，康瑶，王团结，王振中，张宏达，白钢，李正，李文龙

《中国中药杂志》

2022

程传景，丛龙飞，李振强，郝二伟，侯小涛，侯媛媛，白钢，邓家刚

《天津中医药》

2020

扎冲十三味丸抗炎质量标志物筛选及作用机制研究

郭莹莹，常念伟，牛琳，姜民，白钢

《药学学报》

2020

20(S)-Protopanaxatriol promotes the binding of P53 and DNA to regulate the antitumor network via multiomic analysis

Zhihua Wang, Wenbo Wu, Xiangchen Guan, Shuang Guo, Chaowen Li, Ruixue Niu, Jie Gao, Min Jiang, Li‐Ping Bai, Elaine Lai‐Han Leung, Yuanyuan Hou, Zhi‐Hong Jiang, Gang Bai

Acta Pharmaceutica Sinica B

DOI

2020

闫孟琳，丁国钰，丛龙飞，李超雯，牛瑞雪，姜民，侯媛媛，张铁军，白钢，刘昌孝

《中草药》

2019

Guangcui Chu, Dandan Cheng, Wenjuan Liu, Xuefeng Wang, Xiaotao Hou, Yuanyuan Hou, Hongjun Wei, Jiagang Deng, Gang Bai

Chinese Chemical Letters

DOI

2017

复方芒果叶抗炎物质筛选和作用机制研究

刘颖，候小涛，姜民，侯媛媛，张铁军，白钢，邓家刚

《中草药》

2017

复方芒果叶拮抗博莱霉素致小鼠肺纤维化药效学研究

刘颖，邓家刚，白钢，张铁军，姜民

《中药药理与临床》

2017

基于“精准医学”的中药质量认识与评价研究路径

张铁军，白钢，许浚，韩彦琪，龚苏晓，张洪兵

《世界科学技术-中医药现代化》

2017

白钢，丁国钰，侯媛媛，姜民，高洁

《中国中药杂志》

2016

《世界科学技术-中医药现代化》

2014

李红艳，刘艳杰，王倩，邹敏杰，姜民，白钢

《药物评价研究》

2013

基于肾上腺素受体相关肺主宣发的藏象理论及药效物质基础的现代生物学思考

白钢

《中草药》

2013

Journal of Ethnopharmacology

DOI

2012

大黄对瘢痕成纤维细胞增殖抑制作用及其有效成分研究

王倩，张楠楠，李红艳，姜民，高洁，白钢

《药学学报》

2012

Yuanyuan Hou, Yang Yang, Yang Yao, Gang Bai

Chinese Herbal Medicines

2010

Ion Exchange and Adsorption

2006

Preparation and characterization of magnetic microspheres for the purification of interferon α-2b

Yuanyuan Cao, Gang Bai, Jinhua Chen, W TIAN, Shenqi Wang, W YANG

Journal of Chromatography B

DOI

2004

中药中α-糖苷酶抑制剂的筛选(英文)

白钢，王冬莉，曹学琳，肖会姣，耿鹏，刘茜，杨文博

《南开大学学报(自然科学版)》

2004

Screening #alpha#-glucosidase inhibitors in traditional Chinese medicines

Gang Bai, Dongli Wang, Cao Xue-lin, Huijiao Xiao, Peng Geng, Qian Liu, Wenbo Yang

Europe PMC (PubMed Central)

1994

松果有效成分的研究──Ⅲ.油松果多糖的含量测定

李好枝，吕永俊，白钢，曹征

《中草药》

精选作品

期刊论文

基于化学生物学的中药药性-药效关联机制研究策略

基于深度学习与近红外光谱技术对海洋中药马刀的数智评价研究

基于响应面法的复方中药软膏制备优化及其促创面愈合机制初探

系统生物学与化学生物学驱动中药关键质量属性研究

Effects and mechanism of carrier-free self-assembled nanoparticles of natural products in attenuating pulmonary edema

Ginsenoside CK, a major active metabolite of ginsenosides, ameliorates calcium overload-induced arrhythmias and myocardial oxidative injury by targeting CaMKII

Lobetyolin reinforces endothelial cytoskeletal integrity to alleviate Pseudomonas aeruginosa-induced acute lung injury via targeting ACTN1

Advancing TCM-derived active natural product drug discovery for novel drug targets: insights from AI powered tools

Intrinsic warhead-centered cooperative design and evaluation of a covalent UCP2 inhibitor Gen-ip for Alzheimer’s disease

Metabolism and efficacy-oriented screening of Q-markers for platycodon grandiflorum: A comprehensive evaluation framework of inflammation-specific metabolites and pharmacologically active components in chronic pharyngitis treatment

Research progress of polysaccharide detection methods in traditional Chinese medicine

Classification of pulmonary inflammation stages and assessment of multicomponent drug intervention based on spatiotemporal imaging variations utilizing RhB-conjugated poly-L-lysine nanoparticles

Self‐Assembled Baicalein–Resveratrol Nanomedicine Synergistically Modulates Multiple Pathways to Alleviate Pathogen‐Induced Pneumonia

Fuzheng Jiedu formula attenuates acute pneumonia by coordinated regulation of macrophage NLRP3 inflammasome and neutrophil NETs

斑马鱼模型的运动行为学评价方法在中药研究中的应用

基于理气关键药效成分的厚朴药材质量的近红外快速评价

Psoralen alleviates acute lung injury by covalently targeting Cys106 of HMGB1 in macrophages to inhibit inflammatory responses.

Ferulic acid ameliorates TLR4-mediated macrophage activation by irreversibly binding to peroxiredoxin 1 to inhibit its dimerization and secretion.

Ligustilide covalently binds to Cys254 of the creatine kinase, M-type protein, ameliorating acute myocardial ischemia by enhancing the creatine phosphate level.

Corrigendum to "Phillyrin and its metabolites treat pulmonary embolism by targeting PLCβ3 to inhibit platelet activation" [J. Ethnopharmacol. 333 (2024) 118457].

Target deconvolution strategies in TCM: Bridging medicinal properties with therapeutic efficacies

[Application of motor behavior evaluation method of zebrafish model in traditional Chinese medicine research].

Kunxinning granules alleviate perimenopausal syndrome by supplementing estrogen deficiency

Polydatin mitigates thrombosis by inhibiting PHD2-induced proline hydroxylation on collagen, reducing platelet adhesion

o-Phenanthrenequinone-mediated guanidinium nucleophilic attack of tanshinone IIA to Arg145 on Annexin A2 inhibits endothelial-monocyte adhesion and contributes to relieve atherosclerosis

Synergistic Effects of Anthocyanin-Enriched Morus alba L. Extract and Vitamin C: Promising Nutraceutical Ingredients in Functional Food Development for Neuroprotection

Self-assembled baicalein-2,4-decadienal nanomedicine synergistically inhibits PGE2 expression and elicits anti-inflammatory responses

Structure characterization of a polysaccharide isolated from sugarcane leaves and its macrophage polarization activity and beneficial effects for cisplatin treatment of lung cancer

基于氨基酸成分的淡水珍珠及海水珍珠对比分析及近红外快速检测

Honokiol targeting ankyrin repeat domain of TRPV4 ameliorates endothelial permeability in mice inflammatory bowel disease induced by DSS.

Resveratrol targeting NRF2 disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage in mice pulmonary infection.

Catalpolaglycone disrupts mitochondrial thermogenesis by specifically binding to a conserved lysine residue of UCP2 on the proton leak tunnel.

Phillyrin and its metabolites exert antipyretic effects by targeting the NAD+ binding domain of GAPDH, MDH2 and IDH2.

Acacetin alleviates rheumatoid arthritis by targeting HSP90 ATPase domain to promote COX-2 degradation.

Tetrandrine inhibits aldosterone synthesis by covalently targeting CYP11A1 to attenuate hypertension

Ligustilide improves functional constipation by non-covalently activating TRPA1 in colon tissue.

Ligustilide covalently binds to Cys703 in the pre-S1 helix of TRPA1, blocking the opening of channel and relieving pain in rats with acute soft tissue injury.

Phillyrin and its metabolites treat pulmonary embolism by targeting PLCβ3 to inhibit platelet activation.

Baicalein disrupts the KEAP1-NRF2 interaction to alleviate oxidative stress injury by inhibiting M1 macrophage polarization.

Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review

Research on the Mechanism and Material Basis of Corn (Zea mays L.) Waste Regulating Dyslipidemia

Covalent modulation of mPGES1 activity via α,β-unsaturated aldehyde group: Implications for downregulating PGE2 expression and antipyretic response

Revealing drug targets with multimodal bioorthogonal AMPD probes through visual metabolic labeling

Innovation theory, technical methods and industrial application of quality marker of traditional Chinese medicine

Ginsenoside CK targets PHD2 to prevent platelet adhesion and enhance blood circulation by modifying the three-dimensional arrangement of collagen

基于抗炎作用的质量标志物的金银花口服液质量评价研究

Astragaloside IV protects against lung injury and pulmonary fibrosis in COPD by targeting GTP-GDP domain of RAS and downregulating the RAS/RAF/FoxO signaling pathway.

Sinapine targeting PLCβ3 EF hands disrupts Gαq-PLCβ3 interaction and ameliorates cardiovascular diseases.

Metabolic regularity of bioactive compounds in Bufei Jianpi granule in rats using ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry analysis technology.

Ginsenoside CK targeting KEAP1-DGR/Kelch domain disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage

Astragaloside IV targets PRDX6, inhibits the activation of RAC subunit in NADPH oxidase 2 for oxidative damage

Psoralen prevents the inactivation of estradiol and treats osteoporosis via covalently targeting HSD17B2

Costunolide covalently targets and inhibits CaMKII phosphorylation to reduce ischemia-associated brain damage

Ligustilide covalently binds to Cys129 of HMGCS1 to ameliorate dyslipidemia

Magnolol alleviates pulmonary fibrosis inchronic obstructive pulmonary disease by targeting transient receptor potential vanilloid 4‐ankyrin repeat domain

Fuziline Ameliorates Glucose and Lipid Metabolism by Activating Beta Adrenergic Receptors to Stimulate Thermogenesis

Glucuronic acid metabolites of phenolic acids target AKT-PH domain to improve glucose metabolism

速效救心丸中冰片“引经”作用机制研究

桂枝茯苓胶囊的溶出度测试及评价研究

中国-东盟传统药用植物抗呼吸道常见病毒研究进展

Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo

Magnolol and honokiol target TRPC4 to regulate extracellular calcium influx and relax intestinal smooth muscle

Multi-omics analysis reveals the mechanisms of action and therapeutic regimens of traditional Chinese medicine, Bufei Jianpi granules: Implication for COPD drug discovery

Pharmacological effects of Bufei Jianpi granule on chronic obstructive pulmonary disease and its metabolism in rats

Ligustilide attenuates airway remodeling in COPD mice by covalently binding to MH2 domain of Smad3 in pulmonary epithelium, disrupting the Smad3‐SARA interaction

Anti-inflammatory/anti-oxidant properties and the UPLC-QTOF/MS-based metabolomics discrimination of three yellow camellia species

Chemical proteomics combined with metabonomics reveals berberine targets NDUFV1 of complex I in the respiratory chain to regulate energy metabolism

Exploring the Q‐markers of Angelica sinensis (Oliv.) Diels of anti‐platelet aggregation activity based on spectrum–effect relationships

Characterization of deglycosylated metabolites of platycosides reveals their biotransformation after oral administration

CaMKII, that binds with ligustilide, as a potential drug target of Suxiao jiuxin pill, a traditional Chinese medicine to dilate thoracic aorta

Integrated Network Pharmacology and UPLC/Q-TOF-MS Screen System to Exploring Anti-Inflammatory Active Components and Mechanism of Shunaoxin Pills

Ferulic acid targets ACSL1 to ameliorate lipid metabolic disorders in db/db mice

Mechanism Assay of Honeysuckle for Heat-Clearing Based on Metabolites and Metabolomics

GSH-Responsive Drug Delivery System for Active Therapy and Reducing the Side Effects of Bleomycin

A novel mode of action for COX‐2 inhibition: Targeting ATPase domain of HSP90 induces ubiquitin degradation of new client protein COX‐2

The role of Shunaoxin pills in the treatment of chronic cerebral hypoperfusion and its main pharmacodynamic components

Atractylenolide-I covalently binds to CYP11B2, selectively inhibits aldosterone synthesis, and improves hyperaldosteronism

Small-Molecule Fluorogenic Probe for the Detection of Mitochondrial Temperature In Vivo