宋国丽｜深圳大学｜学者主页

2026

浅海温跃层环境下基于水平阵的水面水下目标分辨

李倩岩，王文博，任群言，马力，宋国丽

《声学学报》

2025

Selenoprotein K Confers Protection against Iron Dyshomeostasis-Related Neurotoxicity by Regulating the Palmitoylation of TfR‑1

Shizheng Jia, Yu Li, Xin-Wen Xu, Yan-Ping Huang, Xiaoni Deng, Zhonghao Zhang, Guoli Song

Journal of Agricultural and Food Chemistry

DOI

2025

GluA2 palmitoylation by SELENOK modulates AMPAR assembly and synaptic plasticity in Alzheimer's disease

Jiaying Peng, Zhiyu Cai, Pei Ouyang, Shujing Lin, Shurui Zhang, Danchan Liang, Ziqi Feng, Changbin Chen, Xi-Lin Ye, Guoli Song, Zhonghao Zhang

Redox Biology

DOI

2024

Selenium metabolism and selenoproteins function in brain and encephalopathy

Nan Li, Zhonghao Zhang, Li-Ming Shen, Guoli Song, Jing Tian, Qiong Liu, Jiazuan Ni

Science China Life Sciences

DOI

2024

SELENOK-dependent CD36 palmitoylation regulates microglial functions and Aβ phagocytosis

Pei Ouyang, Zhiyu Cai, Jiaying Peng, Shujing Lin, Xiao-Chun Chen, Changbin Chen, Ziqi Feng, Lin Wang, Guoli Song, Zhonghao Zhang

Redox Biology

DOI

2023

Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway.

Yu Li, Zhonghao Zhang, Shao-Ling Huang, Zhongbao Yue, Xuezhi Yin, Zi-Qi Feng, Xu-Guang Zhang, Guoli Song

Journal of Dairy Science

DOI

2023

Different Effects and Mechanisms of Selenium Compounds in Improving Pathology in Alzheimer’s Disease

Zhonghao Zhang, Jiaying Peng, Yu-Bin Chen, Chao Wang, Chen Chen, Guoli Song

Antioxidants

DOI

2023

Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β.

Ya-Zhou Xie, Chen Chen, Shu-Jing Lin, Xi Yu, Shuixian Ye, Xiaojie Chen, Na Ouyang, Wei Xiong, Chenyang Li, Chen-Shu Xu, Guoli Song, Hai-Qiang Wu

European journal of medicinal chemistry

DOI

2023

SELENOM Knockout Induces Synaptic Deficits and Cognitive Dysfunction by Influencing Brain Glucose Metabolism.

Shujing Lin, Chen Chen, Pei Ouyang, Zhiyu Cai, Xibei Liu, Anwar Abdurahman, Jiaying Peng, Yu Li, Zhonghao Zhang, Guoli Song

Journal of Agricultural and Food Chemistry

DOI

2023

Multifunctional theranostic carbazole-based cyanine for real-time imaging of amyloid-β and therapeutic treatment of multiple pathologies in Alzheimer's disease.

Chen Chen, Xueli Wang, Di Xu, Haifeng Zhang, H. Chan, Zhonghao Zhan, Shizheng Jia, Qingting Song, Guoli Song, Hung-Wing Li, M. Wong

Journal of materials chemistry. B

DOI

2023

Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.

Anwar Abdurahman, Yu Li, Shizheng Jia, Xin-Wen Xu, Shujing Lin, Pei Ouyang, Zhi-Jun He, Zhonghao Zhang, Qiong Liu, Ying Xu, Guoli Song

Metallomics

DOI

2022

利用海洋环境噪声估计浅海海底表层声速

李赫，郭新毅，宋国丽，贾雨晴，马力

《声学学报》

2022

Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer’s Disease

Zhonghao Zhang, Xian-Chun Cao, Jiaxuan Peng, Shao-Ling Huang, Chen Chen, Shizheng Jia, Jia-Zuan Ni, Guoli Song

Antioxidants

DOI

2021

小胶质细胞的神经递质受体在阿尔茨海默病中的作用

陈宇彬，宋国丽

《中国细胞生物学学报》

2021

Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway

Shizheng Jia, Xin-Wen Xu, Zhonghao Zhang, Chen Chen, Yu-Bin Chen, Shao-Ling Huang, Qiong Liu, P. Hoffmann, Guoli Song

Redox Biology

DOI

2021

Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer’s Disease

Chen Chen, Yao Chen, Zhonghao Zhang, Shizheng Jia, Yu-Bin Chen, Shao-Ling Huang, Xin-Wen Xu, Guoli Song

Frontiers in Aging Neuroscience

DOI

2021

Roles of Selenoproteins in Brain Function and the Potential Mechanism of Selenium in Alzheimer’s Disease

Zhonghao Zhang, Guoli Song

Frontiers in Neuroscience

DOI

2021

Corrigendum: Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer's Disease

Chen Chen, Yao Chen, Zhonghao Zhang, Shizheng Jia, Yu-Bin Chen, Shao-Ling Huang, Xin-Wen Xu, Guoli Song

Frontiers in Aging Neuroscience

DOI

2020

Selenium Restores Synaptic Deficits by Modulating NMDA Receptors and Selenoprotein K in an Alzheimer's Disease Model

Zhonghao Zhang, Chen Chen, Shizheng Jia, Xian-Chun Cao, Min Liu, Jing Tian, P. Hoffmann, Hua-Xi Xu, Jiazuan Ni, Guoli Song

Antioxidants and Redox Signaling

DOI

2020

Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway.

Chen Chen, Di Xu, Zhonghao Zhang, Shizheng Jia, Xian-Chun Cao, Yu-Bin Chen, Guoli Song, M. Wong, Hung-Wing Li

Experimental Neurology

DOI

2019

海洋环境噪声中的α稳定分布模型

宋国丽，郭新毅，马力

《声学学报》

DOI

2019

内质网硒蛋白与阿尔茨海默症

贾师政，宋国丽

《中国细胞生物学学报》

2019

确定峰度非高斯海洋环境噪声模型研究

宋国丽，郭新毅，马力

《声学学报》

DOI

2019

Transcriptomic Insights into the Response of the Olfactory Bulb to Selenium Treatment in a Mouse Model of Alzheimer’s Disease

Rui Zheng, Zhonghao Zhang, Yu-Xi Zhao, Chen Chen, Shizheng Jia, Xian-Chun Cao, Li-ming Shen, Jia-Zuan Ni, Guoli Song

International Journal of Molecular Sciences

DOI

2018

南海北部海洋环境噪声谱级空间差异性分析

宋国丽，郭新毅，马力，张乾初

《声学学报》

2018

Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.

Guoli Song, Chen Chen, Qiu-Yan Wu, Zhonghao Zhang, Rui Zheng, Yao Chen, Shizheng Jia, Jia-Zuan Ni

Metallomics

DOI

2018

Effective Theranostic Cyanine for Imaging of Amyloid Species in Vivo and Cognitive Improvements in Mouse Model

Yin-Hui Li, Chen Chen, Di Xu, Chung-Yan Poon, See-Lok Ho, Rui Zheng, Qiong Liu, Guoli Song, Hung-Wing Li, M. Wong

ACS Omega

DOI

2018

Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease.

Zhonghao Zhang, Qiu-Yan Wu, Chen Chen, Rui Zheng, Yao Chen, Jia-Zuan Ni, Guoli Song

Food & Function

DOI

2017

阿尔茨海默症中的线粒体自噬

陈瑶，宋国丽

《中国细胞生物学学报》

2017

Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells

Zhonghao Zhang, Qiu-Yan Wu, Chen Chen, Rui Zheng, Yao Chen, Qiong Liu, Jia-Zuan Ni, Guoli Song

Journal of Alzheimer's Disease

DOI

2017

Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model

Zhonghao Zhang, Qiu-Yan Wu, Rui Zheng, Chen Chen, Yao Chen, Qiong Liu, P. Hoffmann, Jia-Zuan Ni, Guoli Song

Journal of Neuroscience

DOI

2017

Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.

Zhonghao Zhang, Lei Wen, Qiu-Yan Wu, Chen Chen, Rui Zheng, Qiong Liu, Jia-Zuan Ni, Guoli Song

Journal of Agricultural and Food Chemistry

DOI

2017

Selenomethionine promoted hippocampal neurogenesis via the PI3K-Akt-GSK3β-Wnt pathway in a mouse model of Alzheimer's disease.

Rui Zheng, Zhonghao Zhang, Chen Chen, Yao Chen, Shizheng Jia, Qiong Liu, Jia-Zuan Ni, Guoli Song

Biochemical and Biophysical Research Communications - BBRC

DOI

2016

Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer’s Disease

Zhonghao Zhang, Cheng Chen, Qiu-Yan Wu, Rui Zheng, Yao Chen, Qiong Liu, Jia-Zuan Ni, Guoli Song

International Journal of Molecular Sciences

DOI

2016

Selenomethionine reduces the deposition of beta-amyloid plaques by modulating β-secretase and enhancing selenoenzymatic activity in a mouse model of Alzheimer's disease.

Zhonghao Zhang, Chen Chen, Qiu-Yan Wu, Rui Zheng, Qiong Liu, Jia-Zuan Ni, P. Hoffmann, Guoli Song

Metallomics

DOI

2015

内溶酶体–自噬溶酶体对阿尔茨海默症病理进程的影响

吴秋艳，陈琛，宋国丽

《中国细胞生物学学报》

2015

纳米粒子对amyloid-β聚集的影响的研究进展

李冰石，薛山，宋国丽

《深圳大学学报(理工版)》

2015

Application of selenium enriched yeast in control of Alzheimer disease

Si Yang, Guoli Song, Jia-Zuan Ni, Yu-Ying Zhang

2014

蛋氨酸亚砜还原酶的结构特征及与神经退行性疾病的关系

王超，姜亮，王勇，宋国丽，刘琼，杨思林，宋云，倪嘉缵

《中国科学:化学》

2014

硒代蛋氨酸对Aβ1-42诱导N2a细胞损伤的保护作用

温蕾，陈琛，石庆学，张中豪，应明，宋国丽，杨思林，宋云

《中国细胞生物学学报》

2014

静磁场对骨髓间充质干细胞增殖及骨向分化的影响

宋国丽，周翠红，张宇，张小云

《中国康复理论与实践》

2014

不同强度静磁场间歇曝磁对骨髓间充质干细胞增殖及细胞周期的影响

周翠红，张小云，张宇，宋国丽

《中国骨质疏松杂志》

2014

Inhibitory act of selenoprotein P on Cu(+)/Cu(2+)-induced tau aggregation and neurotoxicity.

Xiubo Du, Youbiao Zheng, Zhi Wang, Yi-Jing Chen, Rui Zhou, Guoli Song, Jiazuan Ni, Qiong Liu

Inorganic Chemistry

DOI

2014

Selenomethionine Ameliorates Cognitive Decline, Reduces Tau Hyperphosphorylation, and Reverses Synaptic Deficit in the Triple Transgenic Mouse Model of Alzheimer's Disease

Guoli Song, Zhonghao Zhang, Lei Wen, Chen Chen, Qing Shi, Yu Zhang, Jiazuan Ni, Qiong Liu

Journal of Alzheimer's Disease

DOI

2013

阿尔茨海默病的防治策略研究进展

倪嘉缵，陈平，刘琼，郑易之，何晓阳，宋国丽，应明，续旭

《深圳大学学报(理工版)》

2013

Advance reseach on strategies for the prevention of Alzheimer’s disease: Advance reseach on strategies for the prevention of Alzheimer’s disease

Jiazuan Ni, Ping Chen, Qiong Liu, Yizhi Zheng, Xiao-Yang He, Guoli Song, Ming Ying, Xuezhou Xu

DOI

2011

分子生物学实验教学模式的多样性探索

田生礼，宋国丽，李辉，张建华

《教育教学论坛》

2009

不同强度的静磁场对K562细胞的作用

宋国丽，苏海静，张小云

《中国康复医学杂志》

2006

旋转磁场对放射损伤小鼠造血保护作用的研究

季百苗，宋国丽，张小云

《中华物理医学与康复杂志》

2006

旋转恒定磁场对化疗损伤小鼠造血功能保护作用的研究

宋国丽，季百苗，张小云

《中国康复理论与实践》

2006

抗CD44抗体HI44a对白血病细胞分化与凋亡作用的体外研究

宋国丽，廖晓龙，李彬，刁世勇，张丽艳，肖志坚，韩忠朝

《癌变·畸变·突变》

2006

抗CD44抗体HI44a诱导THP-1细胞凋亡作用的研究

宋国丽，廖晓龙，韩忠朝

《癌变·畸变·突变》

2006

不同频率旋转磁场对放射损伤小鼠的保护及造血作用恢复的研究

宋国丽，王敏，季百苗，徐燕侠，张小云

《中国康复医学杂志》

2005

抗CD44抗体单链抗体构建及表达

宋国丽，李彬，吴立华，刁世勇，韩忠朝

《医学研究杂志》

2005

抗CD33抗体在治疗急性髓系白血病中的应用

宋国丽，韩忠朝

《国际输血及血液学杂志》

2003

血小板第四因子对脐血CD34+细胞趋化作用的研究

冯义，卢士红，宋国丽，张志华，韩忠朝

《中国应用生理学杂志》

2003

腺病毒载体介导的血小板第4因子p17-70 cDNA对荷瘤裸鼠抗血管新生的作用

吴立华，宋国丽，刁世勇，蔡英林，李妍涵，李尚珠，杨仁池，韩忠朝

《中华血液学杂志》

2002

恶性血液系统疾病与血管新生

宋国丽，韩忠朝

《中华血液学杂志》

精选作品

期刊论文

浅海温跃层环境下基于水平阵的水面水下目标分辨

Selenoprotein K Confers Protection against Iron Dyshomeostasis-Related Neurotoxicity by Regulating the Palmitoylation of TfR‑1

GluA2 palmitoylation by SELENOK modulates AMPAR assembly and synaptic plasticity in Alzheimer's disease

Selenium metabolism and selenoproteins function in brain and encephalopathy

SELENOK-dependent CD36 palmitoylation regulates microglial functions and Aβ phagocytosis

Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway.

Different Effects and Mechanisms of Selenium Compounds in Improving Pathology in Alzheimer’s Disease

Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β.

SELENOM Knockout Induces Synaptic Deficits and Cognitive Dysfunction by Influencing Brain Glucose Metabolism.

Multifunctional theranostic carbazole-based cyanine for real-time imaging of amyloid-β and therapeutic treatment of multiple pathologies in Alzheimer's disease.

Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.

利用海洋环境噪声估计浅海海底表层声速

Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer’s Disease

小胶质细胞的神经递质受体在阿尔茨海默病中的作用

Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway

Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer’s Disease

Roles of Selenoproteins in Brain Function and the Potential Mechanism of Selenium in Alzheimer’s Disease

Corrigendum: Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer's Disease

Selenium Restores Synaptic Deficits by Modulating NMDA Receptors and Selenoprotein K in an Alzheimer's Disease Model

Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway.

海洋环境噪声中的α稳定分布模型

内质网硒蛋白与阿尔茨海默症

确定峰度非高斯海洋环境噪声模型研究

Transcriptomic Insights into the Response of the Olfactory Bulb to Selenium Treatment in a Mouse Model of Alzheimer’s Disease

南海北部海洋环境噪声谱级空间差异性分析

Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.

Effective Theranostic Cyanine for Imaging of Amyloid Species in Vivo and Cognitive Improvements in Mouse Model

Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease.

阿尔茨海默症中的线粒体自噬

Selenomethionine Attenuates the Amyloid-β Level by Both Inhibiting Amyloid-β Production and Modulating Autophagy in Neuron-2a/AβPPswe Cells

Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model

Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.

Selenomethionine promoted hippocampal neurogenesis via the PI3K-Akt-GSK3β-Wnt pathway in a mouse model of Alzheimer's disease.

Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer’s Disease

Selenomethionine reduces the deposition of beta-amyloid plaques by modulating β-secretase and enhancing selenoenzymatic activity in a mouse model of Alzheimer's disease.

内溶酶体–自噬溶酶体对阿尔茨海默症病理进程的影响

纳米粒子对amyloid-β聚集的影响的研究进展

Application of selenium enriched yeast in control of Alzheimer disease

蛋氨酸亚砜还原酶的结构特征及与神经退行性疾病的关系

硒代蛋氨酸对Aβ1-42诱导N2a细胞损伤的保护作用

静磁场对骨髓间充质干细胞增殖及骨向分化的影响

不同强度静磁场间歇曝磁对骨髓间充质干细胞增殖及细胞周期的影响

Inhibitory act of selenoprotein P on Cu(+)/Cu(2+)-induced tau aggregation and neurotoxicity.

Selenomethionine Ameliorates Cognitive Decline, Reduces Tau Hyperphosphorylation, and Reverses Synaptic Deficit in the Triple Transgenic Mouse Model of Alzheimer's Disease

阿尔茨海默病的防治策略研究进展

Advance reseach on strategies for the prevention of Alzheimer’s disease: Advance reseach on strategies for the prevention of Alzheimer’s disease

分子生物学实验教学模式的多样性探索

不同强度的静磁场对K562细胞的作用

旋转磁场对放射损伤小鼠造血保护作用的研究

旋转恒定磁场对化疗损伤小鼠造血功能保护作用的研究

抗CD44抗体HI44a对白血病细胞分化与凋亡作用的体外研究

抗CD44抗体HI44a诱导THP-1细胞凋亡作用的研究

不同频率旋转磁场对放射损伤小鼠的保护及造血作用恢复的研究

抗CD44抗体单链抗体构建及表达

抗CD33抗体在治疗急性髓系白血病中的应用

血小板第四因子对脐血CD34+细胞趋化作用的研究

腺病毒载体介导的血小板第4因子p17-70 cDNA对荷瘤裸鼠抗血管新生的作用

恶性血液系统疾病与血管新生

会议论文

硒化合物干预阿尔茨海默症的作用机制研究

硒和钒干预阿尔茨海默症小鼠病理进程的高分辨成像及作用通路研究

南海北部海洋环境噪声垂直分布特性分析

抗CD44抗体对白血病细胞分化凋亡作用的体外研究