陈莎｜重庆医科大学｜学者主页

2026

Corrigendum to “Protocatechuic acid suppresses ferroptosis to protect against hypoxic-ischemic encephalopathy by targeting the HIF-1α/VEGFA axis” [Phytomedicine 143 (2025) 156900]

Xiaoling Zhang, Jingjing Luo, Laxman Bharati, Ziyu Hua, Sha Chen, Zhi Dong

Phytomedicine

DOI

2026

Paeoniflorin Alleviates Oxygen–Glucose Deprivation/Reoxygenation Injury by Mediating Crosstalk Between Neurons and Endothelial Cells Through the VEGF/PI3K-AKT/mTOR Pathway

Zike Xu, Hongxia Luo, Yimin Zhao, Xuhui Wang, Sha Chen

Pharmaceuticals

DOI

2026

Corrigendum to “Cuproptosis involvement in neonatal ischemic-hypoxic encephalopathy through the COMMD1/ATP7A signaling axis” [Biochem. Pharmacol. 239 (2025) 1–17/117054]

Jingjing Luo, Xiaoling Zhang, Laxman Bharati, Ziyu Hua, Sha Chen, Zhi Dong

Biochemical Pharmacology

DOI

2026

The early metabolic cardiac targets of empagliflozin during the development of heart failure, independent of SGLT2 inhibition.

Sha Chen, Xin Hu, Qian Wang, D. Bakker, I. van der Made, A. M. Tebbens, Ying-Yin Guan, Myrto Lykidou, Femke K. J. van Goor, M. Hollmann, Nina C. Weber, M. van Weeghel, B. Schomakers, Michael P. Pieper, R. Coronel, E. E. Creemers, C. Zuurbier

Metabolism: Clinical and Experimental

DOI

2024

香叶醇通过调控Nrf2/HO-1途径调节氧化应激减轻大鼠脑缺血/再灌注损伤

罗佳，吴宇，刘京东，陈莎，董志

《中国药理学通报》

2024

Empagliflozin mitigates cardiac hypertrophy through cardiac RSK/NHE-1 inhibition.

Sha Chen, Kenneth Overberg, Z. Ghouse, M. Hollmann, Nina C. Weber, Ruben Coronel, C. Zuurbier

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI

2024

Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2

Sha Chen, Qian Wang, D. Bakker, Xin Hu, Liping Zhang, I. van der Made, A. M. Tebbens, Csenger Kovácsházi, Z. Giricz, G. Brenner, P. Ferdinandy, G. Schaart, A. Gemmink, M. Hesselink, M. Rivaud, M. Pieper, M. Hollmann, Nina C. Weber, J. Balligand, E. E. Creemers, Ruben Coronel, C. Zuurbier

Basic Research in Cardiology

DOI

2023

Sodium Glucose Cotransporter-2 Inhibitor Empagliflozin Reduces Infarct Size Independently of Sodium Glucose Cotransporter-2.

Sha Chen, Qian Wang, Andriana Christodoulou, Nikolaos Mylonas, Diane Bakker, R. Nederlof, M. Hollmann, N. Weber, R. Coronel, Vincent Wakker, V. Christoffels, I. Andreadou, C. Zuurbier

Circulation

DOI

2023

Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

Sha Chen, C. Schumacher, S. V. van Amersfoorth, J. Fiolet, A. Baartscheer, M. Veldkamp, R. Coronel, C. Zuurbier

Frontiers in Physiology

DOI

2022

Direct cardiac effects of SGLT2 inhibitors

Sha Chen, R. Coronel, M. Hollmann, N. Weber, C. Zuurbier

Cardiovascular Diabetology

DOI

2021

棕榈酰转移酶ZDHHC3对脑缺血-再灌注损伤的影响

王萱，陈莎，邓玲，刘京东，赵虹霞，刘胜伟，董志

《中国病理生理杂志》

2021

肝癌细胞免疫治疗研究进展

卢梅，戴锴，陈莎

《医学综述》

2020

Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts

Hong Zhang, L. Uthman, Diane Bakker, Sahinda Sari, Sha Chen, M. Hollmann, R. Coronel, N. Weber, S. Houten, M. van Weeghel, C. Zuurbier

Frontiers in Cardiovascular Medicine

DOI

2019

[Study of the Role and Mechanism of Asprosin/Spartin Pathway in Cardiac Microvascular Endothelial Injury Induced by Diabete Mellitus].

Sha Chen, Xiong Wang, Chenming Qiu, Juan-Ni Hou, Xiao-yu Wei, Chao-xue Xiang, Ming-yang Tang, Rui Zhang, Hai-Feng Pei

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

2018

Potential Protective Mechanism in the Cardiac Microvascular Injury

Xiuchuan Li, Juan-Ni Hou, Jin Du, Jian Feng, Yi Yang, Yang Shen, Sha Chen, Juan Feng, Da-Chun Yang, De Li, Hai-Feng Pei, Yong-Jian Yang

HYPERTENSION

DOI

2018

GW29-e0099 Effect and mechanism of quercetin on impairment of cardiac microvascular endothelial cells induced by high glucose

Sha Chen, Jian Feng, Juan-Ni Hou, Yang Shen, Hai-Feng Pei

Journal of the American College of Cardiology

DOI

2018

The role of Tom70 in cardiac microvascular endothelial cell damage induced by high fat and high glucose

Juan-Ni Hou, Jin Du, Xiuchuan Li, Sha Chen, Jian Feng, Juan Feng, Yue Tian, Yi Yang, Hai-Feng Pei, Da-Chun Yang

2017

Effect and mechanism of uncoupling protein 2 on cardiomyocyte apoptosis induced by high glucose, high lipid and high uric acid

Yue Tian, Yi Yang, Lei He, Juan-Ni Hou, Jin Du, Sha Chen, Ting Wang, Hai-Feng Pei, Yong-Jian Yang

2017

Protection of MICU1 against myocardial hypertrophy induced by angiotensin II

Yi Yang, Yue Tian, Yang Shen, Mei-Li Guan, Sha Chen, Jian Feng, Hai-Feng Pei, Yong-Jian Yang

2017

Effect of perilipin-5 on apoptosis of cardiac microvascular endothelial cells induced by high fat and high glucose in mice

Jin Du, Juan-Ni Hou, Xiuchuan Li, Yi Yang, Jian Feng, Sha Chen, Yong-Jian Yang, Hai-Feng Pei

2005

Temporal dynamics of cerebro-cerebellar network recruitment during a cognitive task

SHA Chen, JE Desmond

Neuropsychologia，Vol. 43, No. 9

DOI

2003

A study of persistent post-concussion symptoms in mild head trauma using positron emission tomography

SHA Chen, DA Kareken, PS Fastenau, LE Trexler, GD Hutchins

Journal Of Neurology Neurosurgery And Psychiatry，Vol. 740, No. 3

DOI

1998

Buprenorphine alters ethanol self-administration in rats: dose-response and time-dependent effects

HL June, CR Cason, SHA Chen, MJ Lewis

Psychopharmacology，Vol. 1400, No. 1

DOI

陈莎

精选作品

期刊论文

Corrigendum to “Protocatechuic acid suppresses ferroptosis to protect against hypoxic-ischemic encephalopathy by targeting the HIF-1α/VEGFA axis” [Phytomedicine 143 (2025) 156900]

Paeoniflorin Alleviates Oxygen–Glucose Deprivation/Reoxygenation Injury by Mediating Crosstalk Between Neurons and Endothelial Cells Through the VEGF/PI3K-AKT/mTOR Pathway

Corrigendum to “Cuproptosis involvement in neonatal ischemic-hypoxic encephalopathy through the COMMD1/ATP7A signaling axis” [Biochem. Pharmacol. 239 (2025) 1–17/117054]

The early metabolic cardiac targets of empagliflozin during the development of heart failure, independent of SGLT2 inhibition.

香叶醇通过调控Nrf2/HO-1途径调节氧化应激减轻大鼠脑缺血/再灌注损伤

Empagliflozin mitigates cardiac hypertrophy through cardiac RSK/NHE-1 inhibition.

Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2

Sodium Glucose Cotransporter-2 Inhibitor Empagliflozin Reduces Infarct Size Independently of Sodium Glucose Cotransporter-2.

Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

Direct cardiac effects of SGLT2 inhibitors

棕榈酰转移酶ZDHHC3对脑缺血-再灌注损伤的影响

肝癌细胞免疫治疗研究进展

Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts

[Study of the Role and Mechanism of Asprosin/Spartin Pathway in Cardiac Microvascular Endothelial Injury Induced by Diabete Mellitus].

Potential Protective Mechanism in the Cardiac Microvascular Injury

GW29-e0099 Effect and mechanism of quercetin on impairment of cardiac microvascular endothelial cells induced by high glucose

The role of Tom70 in cardiac microvascular endothelial cell damage induced by high fat and high glucose

Effect and mechanism of uncoupling protein 2 on cardiomyocyte apoptosis induced by high glucose, high lipid and high uric acid

Protection of MICU1 against myocardial hypertrophy induced by angiotensin II

Effect of perilipin-5 on apoptosis of cardiac microvascular endothelial cells induced by high fat and high glucose in mice

Temporal dynamics of cerebro-cerebellar network recruitment during a cognitive task

A study of persistent post-concussion symptoms in mild head trauma using positron emission tomography

Buprenorphine alters ethanol self-administration in rats: dose-response and time-dependent effects

研究方向