李庆阁｜厦门大学｜学者主页

2026

A field-deployable high-resolution SNP genotyping platform for rapid surveillance of Yersinia pestis

Ying Liu, Qiu-Ying Huang, Yarong Wu, Jiahao Zheng, Ming-Zhu Xu, Liu Guo, Fang Liu, Meng-Nan Cui, Yan Guo, Xiujuan Zuo, Jian-Yun Li, Xin Wang, Huai-Qi Jing, Rui-Fu Yang, Yu-Jun Cui, Qingge Li

Virulence

DOI

2026

Etiologic diagnosis of suspected tuberculous meningitis by multiplex PCR of cerebrospinal fluid

Haohao Wang, Mingxiang Huang, Jiabao Song, Jinding Zhang, Shangying Yang, Xiaoxing Zhang, Yongzhen He, Yiqun Liao, Ye Xu, Qingge Li

Journal of Clinical Microbiology

DOI

2026

Comparative performance of L1- and E6/E7-targeted HPV genotyping assays based on a unified MeltArray platform

Ying Liu, Huihui Qu, Feng Zhang, Shuyang Gan, Yongqing Lai, Xiaoxing Zhang, Meiying Zhong, Xinyi Yang, Y Xu, Yiqun Liao, Qingge Li

Microbiology Spectrum

DOI

2025

Enhanced diagnosis of tuberculous pleurisy using a multiplex droplet digital PCR assay targeting circulating mycobacterial DNA

Siqi Zhang, Ye Xu, Mingxiang Huang, Yuying Pan, J. Shangguan, Rui Peng, Xiaoman Hu, Fang Zheng, Na Luo, Xiaohong Chen, Qingge Li

Thorax

DOI

2025

Innovative rapid screening for complex BCR-ABL1 kinase domain mutations in TKI-treated leukaemia patients

Yanping Lan, Jun Deng, Pujing He, Wen Huang, Anqi Zhu, Xiaoxia Guo, Lv Xiong, Qiuying Huang, Yu Hu, Qingge Li

British Journal of Cancer

DOI

2025

Identification and quantification of gyrA variants in fluoroquinolone-resistant Mycobacterium tuberculosis in a MeltArray reaction

Chunxia Tu, Biyi Su, Yunfan Xiong, Zihan Xia, Chunlin Xiang, Yaoju Tan, Ye Xu, Qingge Li

Journal of Clinical Microbiology

DOI

2024

人乳头瘤病毒分子检测方法研究进展

甘舒扬，廖逸群，李庆阁

《厦门大学学报(自然科学版)》

2024

Molecular serotyping of diarrheagenic Escherichia coli with a MeltArray assay reveals distinct correlation between serotype and pathotype

Chen Du, Yiqun Liao, Congcong Ding, Jiayu Huang, Shujuan Zhou, Yiyan Xu, Yiyan Xu, Zhaohui Yang, Xiaolu Shi, Yinghui Li, Min Jiang, Le Zuo, Minxu Li, Shengzhe Bian, Na Xiao, Liqiang Li, Xu Ye, Xu Ye, Qinghua Hu, Qingge Li

Gut Microbes

DOI

2024

Multiplex Asymmetric PCR by Combining the Amplification Refractory Mutation System with the Homo-Tag-Assisted Nondimer System

Ying Liu, Yinghua Liu, Guo Liu, Yazhe Wu, Wang Yf, Lingzhen Xu, Mingzhu Xu, Siyu Huang, Ping Chen, Ting Wang, Qiuying Huang, Qingge Li

Analytical Chemistry

DOI

2023

Ability of the MeltPro MTB/PZA Assay to Detect Susceptibility to Pyrazinamide in Rifampin-Resistant Tuberculosis Patients

Rong Li, Yang Li, Xinchang Chen, Lina Jia, Hongying Yu, Ya Huang, Qian-Hong Wu, Mingying Xiao, Shi-Jia Ge, Yilin Zhang, Zhen Feng, Qingge Li, Ye Xu, Wenzhi Shi, Feng Sun, Wen Zhang

Microbiology spectrum

DOI

2023

Quantification of Isoniazid-Heteroresistant Mycobacterium tuberculosis Using Droplet Digital PCR

Siqi Zhang, Xiao-Hong Chen, Zhonghui Lin, Yao-Ju Tan, Bin Liang, Yu-Ying Pan, Ming-Xiang Huang, B. Su, Xiaoman Hu, Ye Xu, Qingge Li

Journal of Clinical Microbiology

DOI

2023

Highly Sensitive Detection of PIK3CA Mutations by Looping-Out Probes-Based Melting Curve Analysis

Boheng Xu, Yanping Lan, Danjiao Luo, Ya-Yun Zheng, Runfang Ni, Guoqiang Su, Qiu-Ying Huang, Qingge Li

Biochemical Genetics

DOI

2023

Single-tube protocol for culture-independent spoligotyping of Mycobacterium tuberculosis based on MeltArray

Zihan Xia, Biyi Su, Chunxia Tu, Siyang Sun, Yaoju Tan, Ye Xu, Qingge Li

Journal of Clinical Microbiology

DOI

2023

Direct identification of pathogens via microbial cellular DNA in whole blood by MeltArray

Jiabao Song, Su Lin, Lin Zhu, Yong Lin, Wenbin An, Jinding Zhang, Haohao Wang, Zhuan Yang, Yiqun Liao, Ye Xu, Qingge Li

Microbial Biotechnology

DOI

2023

Epidemiological Insights into the Omicron Outbreak via MeltArray-Assisted Real-Time Tracking of SARS-CoV-2 Variants

Ting Yan, Rongrong Zheng, Yinghui Li, Siyang Sun, Xiaohong Zeng, Zhijiao Yue, Yiqun Liao, Qinghua Hu, Ye Xu, Qingge Li

Viruses

DOI

2023

Accurate Detection of Multiple Tumor Mutations in Formalin-Fixed Paraffin-Embedded Tissues by Coupling Sequence Artifacts Elimination and Mutation Enrichment With MeltArray

Yanping Lan, Bo-Heng Xu, Yuxin Xi, Yi Luo, Xiaoxia Guo, Zhibin Huang, Danjiao Luo, Anqi Zhu, Pujing He, Changxing Li, Qiuying Huang, Qingge Li

Laboratory Investigation

DOI

2023

Identification of pneumococcal serotypes with individual recognition of vaccine types by a highly multiplexed real-time PCR-based MeltArray approach

Shujuan Zhou, Jie Che, Xuran Wang, Yong Lin, Jianjun Niu, Weitong Liang, Li Xu, Maojun Zhang, Yiqun Liao, Zhujun Shao, Qingge Li

Journal of Microbiology Immunology and Infection

DOI

2023

CovidShiny: An Integrated Web Tool for SARS-CoV-2 Mutation Profiling and Molecular Diagnosis Assay Evaluation In Silico

Shaoqian Ma, Gezhi Xiao, Xusheng Deng, Mengsha Tong, Jialiang Huang, Qingge Li, Yongyou Zhang

Viruses

DOI

2022

Highly multiplex PCR assays by coupling the 5′-flap endonuclease activity of Taq DNA polymerase and molecular beacon reporters

Qiu-Ying Huang, Dongmei Chen, Chen Du, Qiaoqiao Liu, Su Lin, Lanlan Liang, Ye Xu, Yi-Qun Liao, Qingge Li

Proceedings of the National Academy of Sciences of the United States of America

DOI

2022

Qualitative and Quantitative Detection of Multiple Sexually Transmitted Infection Pathogens Reveals Distinct Associations with Cervicitis and Vaginitis

Wen-Tyng Kang, Hai-Bo Xu, Yi-Qun Liao, Qi-Wei Guo, Qiu-Ying Huang, Ye Xu, Qingge Li

Microbiology spectrum

DOI

2022

Accessible and Adaptable Multiplexed Real-Time PCR Approaches to Identify SARS-CoV-2 Variants of Concern

Ting-bo Yan, Ye Xu, R. Zheng, Xiaohong Zeng, Ze-Hui Chen, Su Lin, Zi-Han Xia, Yi-Qun Liao, Yongyou Zhang, Qingge Li

Microbiology spectrum

DOI

2021

A Novel Molecular Method for Simultaneous Identification of Vibrio parahaemolyticus 57 K-Serogroups Using Probe Melting Curve Analysis

Lin-Ying Lu, Minxu Li, Yinghui Li, Min Jiang, Yi-Xiang Jiang, Xiao-Lu Shi, Le Zuo, Lei Wang, S. Bian, Yaqun Qiu, R. Cai, Yi-Qun Liao, Qingge Li, Li-Qiang Li, Qing-Hua Hu

Frontiers in Cellular and Infection Microbiology

DOI

2021

Genotypic diversity of Mycobacterium tuberculosis isolates and its association with drug-resistance status in Xinjiang, China.

Wei-zhi Deng, Xiaohong Zeng, Zi-Han Xia, Ye Xu, Xing Yi, Jun-Lian Li, Quan Wang, Qingge Li

Tuberculosis

DOI

2021

Segmental duplication as potential biomarkers for non-invasive prenatal testing of aneuploidies

Xinwen Chen, Yifan Li, Qiu-Ying Huang, Xingming Lin, Xu-Dong Wang, Ya-fang Wang, Y. Liu, Qiu-Shun He, Yinghua Liu, Ting Wang, Zhisong Ji, Qingge Li

EBioMedicine

DOI

2020

Y染色体AZF基因微缺失在诊断苏南地区男性不育患者中的研究

刘英华，宋小艳，李庆阁，黄秋英，刘敏娟，向菁菁，唐慧，毛君

《中国优生与遗传杂志》

DOI

2019

锁核酸修饰探针熔解曲线分析在Kras基因突变检测中的应用

倪润芳，黄秋英，钱思雨，李腾文，苏国强，李庆阁

《厦门大学学报(自然科学版)》

2019

基于多色探针熔解曲线分析技术的华法林个体化用药相关基因多态性快速检测方法

黄秋英，夏众敏，洪国粦，李庆阁

《厦门大学学报(自然科学版)》

2019

结核分枝杆菌新型间隔区寡核甘酸分型技术临床应用价值研究

李辉，王少华，石洁，马晓光，朱岩昆，郑丹薇，周杨，许晔，李庆阁，赵雁林

《现代疾病预防控制》

DOI

2019

Multiplex ligation reaction based on probe melting curve analysis: a pragmatic approach for the identification of 30 common Salmonella serovars

Le Zuo, Min Jiang, Yi-Xiang Jiang, Xiao-Lu Shi, Yinghui Li, Yi-Man Lin, Yaqun Qiu, Yinhua Deng, Minxu Li, Zeren Lin, Yi-Qun Liao, Jian-Bin Xie, Qingge Li, Qing-Hua Hu

Annals of Clinical Microbiology and Antimicrobials

DOI

2019

Profile of MeltPro® HPV test for human papillomavirus genotyping and cervical precancer screening

Yi-Qun Liao, Qingge Li

Expert Review of Molecular Diagnostics

DOI

2019

Simultaneous Identification of Clinically Common Vibrio parahaemolyticus Serotypes Using Probe Melting Curve Analysis

Minxu Li, Yi-Xiang Jiang, Xiao-Lu Shi, Yinghui Li, Min Jiang, Yi-Man Lin, Yaqun Qiu, Le Zuo, Yinhua Deng, Zeren Lin, Yi-Qun Liao, Qingge Li, Qing-Hua Hu

Frontiers in Cellular and Infection Microbiology

DOI

2019

Chinese newborn screening for the incidence of G6PD deficiency and variant of G6PD gene from 2013 to 2017

Zhi-Dai Liu, Chao-Wen Yu, Qingge Li, R. Cai, Yi-Ping Qu, Wei-Peng Wang, Jie Wang, Jinwen Feng, Wen-Bin Zhu, Ming-Cai Ou, Weitong Huang, Deguo Tang, Wei Guo, Fangjie Liu, Yan-Hua Chen, Li-Fang Fu, Yan-Xia Zhou, Wen-Qiong Lv, Hang Zhang, Juan-Juan Zhang, Ming Wang, Jing Yang, Ke-Xing Wan, Jing-kun Miao, Zhao-Jian Yuan, Hao Liu, Xiaoyan He, Wen-Jie Li, Wen-Gao Chen, Lixin Ye, Yajun Chen, Shuodan Huang, Hai-Ping Liu, Hongxiang Ding, Xinhui Gan, Shu-Yuan Wang, Rong Qiang, Minhong Gong, Ping Teng, Hua Wang, Muping Zhou, Hong-Wei Wei, Xiang-Ju Liu, Kaijie Tang, Ya-Hong Ma, Hongliang Wu, Xiao-Li Shu, Yi-Zhen Chen, Dan-Yan Zhuang, Hui Li, Zhi Liu, Xiu-Lian Liu, Yao Chen, Li-Dan Zhu, Xiaoyan Zhu, Cai-Hong Mo, Hua Tang, F. Yin, Zhi-Bing Shao, Penghui Zhang, Bin Peng, Qing Lu, Zhi-Guo Wang, L. Zou

Human Mutation

DOI

2018

多色探针熔解曲线法在卡马西平不良反应相关基因检测中的临床评价

裴斌，郭晓彤，冉鹏，黄秋英，洪素云，钟雪婷，李庆阁

《中国现代应用药学》

2018

多色探针熔解曲线法应用于别嘌呤醇不良反应相关基因HLA-B* 58∶01的检测

裴斌，郭晓彤，冉鹏，黄秋英，洪素云，钟雪婷，李庆阁

《中国输血杂志》

2018

Correction to: Spectrum of PAH gene variants among a population of Han Chinese patients with phenylketonuria from northern China

Ning Liu, Qiu-Ying Huang, Qingge Li, Dehua Zhao, Xiao-Le Li, L. Cui, Ying Bai, Yin Feng, X. Kong

BMC Medical Genetics

DOI

2018

Probe based melting curve analysis in anti-HBV drug resistance gene mutation detection

M. Athar, Y. Mou, Yu-Zhen Wu, Ye Xu, Jian-Hua Wu, Zhenxing Xu, Zulfiqar Hayder, Saeed Khan, Muhammad Idrees Khan, M. Nasir, Yi-Qun Liao, Qingge Li

2018

McSpoligotyping, a One-Step Melting Curve Analysis-Based Protocol for Spoligotyping of Mycobacterium tuberculosis

Xiaohong Zeng, Ye Xu, Yang Zhou, Hui Li, R. Zheng, Yao-Ju Tan, Bingqi Sun, Yan-Lin Zhao, Qingge Li

Journal of Clinical Microbiology

DOI

2018

Rapid Identification of Clinically Relevant Mycobacterium Species by Multicolor Melting Curve Analysis

Ye Xu, Bin Liang, Chen Du, X. Tian, Xing-Shan Cai, Yanjie Hou, Hui Li, R. Zheng, Jun-Lian Li, Yu-Qin Liu, Kaili Wang, Muhammad Ammar Athar, Yao-Ju Tan, Qingge Li

Journal of Clinical Microbiology

DOI

2017

Simultaneous Genotyping of α-Thalassemia Deletional and Nondeletional Mutations by Real-Time PCR-Based Multicolor Melting Curve Analysis.

Qiu-Ying Huang, Xu-Dong Wang, Ning Tang, Tizhen Yan, Ping Chen, Qingge Li

Journal of Molecular Diagnostics

DOI

2017

Spectrum of PAH gene variants among a population of Han Chinese patients with phenylketonuria from northern China

Ning Liu, Qiu-Ying Huang, Qingge Li, Dehua Zhao, Xiao-Le Li, L. Cui, Ying Bai, Yin Feng, X. Kong

BMC Medical Genetics

DOI

2017

Highly Sensitive Detection of Isoniazid Heteroresistance in Mycobacterium tuberculosis by DeepMelt Assay

Bin Liang, Yao-Ju Tan, Zi Li, X. Tian, Chen Du, Hui Li, Guoli Li, Xiangyang Yao, Zhongan Wang, Ye Xu, Qingge Li

Journal of Clinical Microbiology

DOI

2017

Rapid and Reliable Detection of Nonsyndromic Hearing Loss Mutations by Multicolor Melting Curve Analysis

Xu-Dong Wang, Yong-Jun Hong, Pei-Yuan Cai, Ning Tang, Ying Chen, Tizhen Yan, Yinghua Liu, Qiu-Ying Huang, Qingge Li

Scientific Reports

DOI

2017

A comparison of the MeltPro® HPV Test with the Cobas® HPV Test for detecting and genotyping 14 high-risk human papillomavirus types

Zhiteng Tang, Ye Xu, Najie Song, Dongqing Zou, Yi-Qun Liao, Qingge Li, Chao Pan

Archives of Virology

DOI

2017

Review: Molecular detection of extended spectrum-β-lactamase- and carbapenemase-producing Enterobacteriaceae in a clinical setting.

I. Rood, Qingge Li

Diagnostic microbiology and infectious disease

DOI

2017

Simultaneous Genotyping of a-Thalassemia Deletional and Nondeletional Mutations by

Qiu-Ying Huang, Xu-Dong Wang, Ning Tang, Tizhen Yan, Ping Chen, Qingge Li

2017

Simultaneous Identification of Ten Bacterial Pathogens Using the Multiplex Ligation Reaction Based on the Probe Melting Curve Analysis

Yi-Xiang Jiang, Lian-Hua He, Ping-Fang Wu, Xiao-Lu Shi, Min Jiang, Yinghui Li, Yi-Man Lin, Yaqun Qiu, F. Bai, Yi-Qun Liao, Qingge Li, Renli Zhang, Qing-Hua Hu

Scientific Reports

DOI

2016

厦门地区遗传性耳聋流行病学调查

王旭东，洪拥军，陈艺文，黄秋英，李庆阁

《中华耳科学杂志》

2016

Rapid detection of G6PD mutations by multicolor melting curve analysis.

Zhongmin Xia, Ping Chen, Ning Tang, Tizhen Yan, Yu-Qiu Zhou, Qi-Zhi Xiao, Qiu-Ying Huang, Qingge Li

Molecular Genetics and Metabolism

DOI

2016

Rapid detection of non-deletional mutations causing α-thalassemia by multicolor melting curve analysis

Qiu-Ying Huang, Xu-Dong Wang, Ning Tang, Chun-Jiang Zhu, Tizhen Yan, Ping Chen, Qingge Li

Clinical Chemistry and Laboratory Medicine

DOI

2016

Spoligotyping of Mycobacterium tuberculosis Complex Isolates by Use of Ligation-Based Amplification and Melting Curve Analysis

Xiaohong Zeng, Hui Li, R. Zheng, N. Kurepina, B. Kreiswirth, Xi-Lin Zhao, Ye Xu, Qingge Li

Journal of Clinical Microbiology

DOI

2016

A strip array for spoligotyping of Mycobacterium tuberculosis complex isolates.

Yiling Tu, Xiaohong Zeng, Hui Li, R. Zheng, Ye Xu, Qingge Li

Journal of Microbiological Methods

DOI

2016

Detection of Anti-Hepatitis B Virus Drug Resistance Mutations Based on Multicolor Melting Curve Analysis

Y. Mou, M. Athar, Yu-Zhen Wu, Ye Xu, Jian-Hua Wu, Zhenxing Xu, Zulfiqar Hayder, Saeed Khan, M. Idrees, M. Nasir, Yi-Qun Liao, Qingge Li

Journal of Clinical Microbiology

DOI

2015

大肠埃希菌和肺炎克雷伯菌质粒型AmpC酶基因型的检测分析

郑港森，刘赞赞，张加勤，黄朝阳，马晓波，李庆阁，宋秀宇

《国际检验医学杂志》

2015

探针熔解曲线法快速检测结核分枝杆菌注射类二线药耐药突变

张婷，付军，王国治，陈保文，杨蕾，卢锦标，许晔，李庆阁

《中国人兽共患病学报》

2015

Rapid detection of HCV genotyping 1a, 1b, 2a, 3a, 3b and 6a in a single reaction using two-melting temperature codes by a real-time PCR-based assay

M. Athar, Ye Xu, Yi-Qun Liao, Qingge Li

DOI

2015

Heptaplex PCR melting curve analysis for rapid detection of plasmid-mediated AmpC β-lactamase genes.

Zan-Zan Liu, Jia-Qin Zhang, Shi-Tao Rao, Li Sun, Jie Zhang, Ran Liu, Gang-Sen Zheng, Xiao-Bo Ma, Shuyi Hou, Xin-Guo Zhuang, Xiu-Yu Song, Qingge Li

Journal of Microbiological Methods

DOI

2015

Evaluation of the MeltPro TB/STR assay for rapid detection of streptomycin resistance in Mycobacterium tuberculosis.

Ting Zhang, Si-Yu Hu, Guoli Li, Hui Li, Xiaoli Liu, Jian-Jun Niu, Feng Wang, Hui-Xin Wen, Ye Xu, Qingge Li

Tuberculosis

DOI

2015

Multicolor Melting Curve Analysis-Based Multilocus Melt Typing of Vibrio parahaemolyticus

Ran Liu, Zan-Zan Liu, Ye Xu, Yi-Qun Liao, Qing-Hua Hu, Jian-Wei Huang, Xiao-Lu Shi, Yinghui Li, Jian-Jun Niu, Qingge Li

PLoS ONE

DOI

2015

[Development of a rapid molecular typing method for Vibrio cholerae using melting curve-based multilocus melt typing].

Shi-Jie Huang, Zan-Zan Liu, Hui-Xin Wen, Li Li, Qingge Li, Jian-Wei Huang

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]

DOI

2014

厦门地区非缺失型α-地中海贫流行病学调查

孔德佳，黄秋英，王旭东，郭奇伟，周裕林，李庆阁

《中国优生与遗传杂志》

DOI

2014

Saliva as a sampling source for the detection of leukemic fusion transcripts

Dongmei Chen, Najie Song, Runfang Ni, Jiangning Zhao, Jia-Sheng Hu, Quanyi Lu, Qingge Li

Journal of Translational Medicine

DOI

2014

Rapid genetic typing of diarrheagenic Escherichia coli using a two-tube modified molecular beacon based multiplex real-time PCR assay and its clinical application

Qing-Liang Chen, Xiao-Lu Shi, Yinghui Li, Yi-Xiang Jiang, Yi-Man Lin, Yaqun Qiu, Qingge Li, Qing-Hua Hu

Annals of Clinical Microbiology and Antimicrobials

DOI

2014

Rapid Detection of Isoniazid Resistance in Mycobacterium tuberculosis Isolates by Use of Real-Time-PCR-Based Melting Curve Analysis

Si-Yu Hu, Guoli Li, Hui Li, Xiaoli Liu, Jian-Jun Niu, Sheng-Mao Quan, Feng Wang, Hui-Xin Wen, Ye Xu, Qingge Li

Journal of Clinical Microbiology

DOI

2014

Fluorescent probe-based lateral flow assay for multiplex nucleic acid detection.

Ye Xu, Yinghua Liu, Yan Wu, Xiaohu Xia, Yi-Qun Liao, Qingge Li

Analytical Chemistry

DOI

2014

Real-Time Bidirectional Pyrophosphorolysis-Activated Polymerization for Quantitative Detection of Somatic Mutations

Najie Song, Xu Zhong, Qingge Li

PLoS ONE

DOI

2014

Deafness susceptibility gene mutation detection kit as well as preparation method and application thereof

Qiu-Ying Huang, Qingge Li, Xu-Dong Wang

2013

荧光PCR探针熔解曲线法检测结核分枝杆菌耐异烟肼突变

马晓光，李辉，石洁，邢进，闫国蕊，李庆阁

《现代预防医学》

2013

用探针熔解曲线法检测急性髓细胞白血病c-kit基因突变

姜国强，赵晓明，王航，李庆阁，鹿全意

《中华临床医师杂志(电子版)》

2013

A highly sensitive europium nanoparticle-based lateral flow immunoassay for detection of chloramphenicol residue

Xiaohu Xia, Ye Xu, Rong-Qin Ke, Heng Zhang, M. Zou, Wei Yang, Qingge Li

Analytical and Bioanalytical Chemistry

DOI

2013

Combination of fluorescence color and melting temperature as a two-dimensional label for homogeneous multiplex PCR detection

Yi-Qun Liao, Xiao-Bo Wang, Chao-Yan Sha, Zhongmin Xia, Qiu-Ying Huang, Qingge Li

Nucleic Acids Research

DOI

2013

Natural phage nanoparticle-mediated real-time immuno-PCR for ultrasensitive detection of protein marker.

Heng Zhang, Ye Xu, Qiu-Ying Huang, C. Yi, Tan Xiao, Qingge Li

Chemical Communications

DOI

2013

A Modified Molecular Beacons–Based Multiplex Real-Time PCR Assay for Simultaneous Detection of Eight Foodborne Pathogens in a Single Reaction and Its Application

Qinghua Hu, Dongyue Lyu, Xiaolu Shi, Yixiang Jiang, Yiman Lin, Yinghui Li, Yaqun Qiu, Lianhua He, Ran Zhang, Qingge Li

Foodborne Pathogens and Disease

DOI

2012

PCR-探针熔解分析法检测结核分枝杆菌利福平耐药性的临床应用

李国利，李庆阁，王倩，张灵霞

《北京医学》

DOI

2012

急性白血病MLL融合基因新检测方法的建立和应用

赵晓明，王航，李志鹏，鹿全意，李庆阁

《中国实验血液学杂志》

2012

Application of europium(III) chelates-bonded silica nanoparticle in time-resolved immunofluorometric detection assay for human thyroid stimulating hormone.

Yu-Lin Zhou, Xiaohu Xia, Ye Xu, Wei Ke, Wei Yang, Qingge Li

Analytica Chimica Acta

DOI

2012

Simultaneous Detection, Genotyping, and Quantification of Human Papillomaviruses by Multicolor Real-Time PCR and Melting Curve Analysis

Yi-Qun Liao, Yu-Lin Zhou, Qi-Wei Guo, Xiao-Ting Xie, E. Luo, Jian Li, Qingge Li

Journal of Clinical Microbiology

DOI

2012

Human Papillomaviruses by Multicolor Real-Time PCR and

Yi-Qun Liao, Yu-Lin Zhou, Qi-Wei Guo, Xiao-Ting Xie, E. Luo, Jian Li, Qingge Li

2012

Molecular diagnosis of β-thalassemia

Qingge Li

Zhonghua jianyan yixue zazhi

DOI

2012

[A rapid screening program on the resistance to streptomycin and ethambutol in Mycobacterium tuberculosis isolates by PCR melting curve analysis].

Feng Wang, Si-yu Hu, Jing Gui, Yun-yong Cui, Xiaoli Liu, Qingge Li

PubMed

2011

急性髓系白血病NPM1基因突变检测方法的研究

李志鹏，张绚，赵晓明，李庆阁，陈亚玫，鹿全意

《中国实验血液学杂志》

2011

PCR-探针熔解分析法检测结核分枝杆菌氟喹诺酮耐药基因突变的临床应用评价

李国利，李庆阁，王倩，陈澎，张灵霞

《中华临床医师杂志(电子版)》

2011

荧光PCR探针熔解曲线法检测结核分枝杆菌耐利福平突变研究

马艳艳，李辉，赵东阳，李静，李庆阁

《中国国境卫生检疫杂志》

2011

探针熔解分析法快速检测结核分枝杆菌链霉素耐药突变

张向东，张婷，牛建军，温慧欣，胡思玉，李庆阁

《中国人兽共患病学报》

2011

荧光PCR熔解曲线法检测结核分枝杆菌耐利福平突变研究

马艳艳，李辉，赵东阳，李庆阁

《口岸卫生控制》

2011

Multicolor Combinatorial Probe Coding for Real-Time PCR

Qiu-Ying Huang, Linlin Zheng, Yu-Mei Zhu, Jiafeng Zhang, Hui-Xin Wen, Jian-Wei Huang, Jian-Jun Niu, Xi-Lin Zhao, Qingge Li

PLoS ONE

DOI

2011

Multiplex Fluorescence Melting Curve Analysis for Mutation Detection with Dual-Labeled, Self-Quenched Probes

Qiu-Ying Huang, Zan-Zan Liu, Yi-Qun Liao, Xiaoyun Chen, Yi Zhang, Qingge Li

PLoS ONE

DOI

2011

A melting curve analysis--based PCR assay for one-step genotyping of β-thalassemia mutations a multicenter validation.

F. Xiong, Qiu-Ying Huang, Xiaoyun Chen, Yu-Qiu Zhou, Xinhua Zhang, R. Cai, Yajun Chen, Jian-Sheng Xie, S. Feng, Xiao-Feng Wei, Qi-Zhi Xiao, Tian-Lang Zhang, Shiqiang Luo, Xue-Niu Yang, Ying Hao, Yan-Xia Qu, Qingge Li, Xiang-Min Xu

Journal of Molecular Diagnostics

DOI

2011

Molecular diagnosis and targeted therapy of a pediatric chronic eosinophilic leukemia patient carrying TPM3‐PDGFRB Fusion

Zhi-Peng Li, Rong Yang, Jiangning Zhao, R. Yuan, Quanyi Lu, Qingge Li, W. Tse

Pediatric Blood & Cancer

DOI

2011

Chromosome aneuploidy detection kit based on real-time fluorescent PCR

Min Xia, Qingge Li, Xiao-Bo Wang, Qi-Wei Guo, Qiu-Ying Huang

2011

Application and evaluation of a probe melting analysis-based assay for detection of Isoniazid-resistant mutations in Mycobacterium tuberculosis

Si-yu Hu, Shengmao Quan, Qingge Li

Zhonghua jianyan yixue zazhi

DOI

2010

Multicolor Real-Time PCR Genotyping of ABO System Using Displacing Probes

Li Ruan, Huian Zhao, Qingge Li

Journal Of Forensic Sciences，Vol. 550, No. 10

DOI

2010

Tandem conjugation of enzyme and antibody on silica nanoparticle for enzyme immunoassay.

Rong-Qin Ke, Wei Yang, Xiaohu Xia, Ye Xu, Qingge Li

Analytical Biochemistry

DOI

2010

Simultaneous detection of trisomies 13, 18, and 21 with multiplex ligation-dependent probe amplification-based real-time PCR.

Qi-Wei Guo, Yu-Lin Zhou, Xiao-Bo Wang, Qingge Li

Clinical Chemistry

DOI

2009

实时荧光PCR同时检测金黄色葡萄球菌和大肠杆菌O157:H7

吴海娟，扈庆华，李庆阁，石晓路，兰全学，刘涛，林一曼

《中国热带医学》

2009

产单核李斯特菌的改良分子信标荧光PCR-磁捕获快速检测体系的建立

王冰，扈庆华，石晓路，李庆阁，郑琳琳，林一曼，段永翔

《现代预防医学》

2009

Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells

Ye Xu, J. Phillips, Ji-Lin Yan, Qingge Li, Zhifang Fan, Weihong Tan

Analytical Chemistry

DOI

2009

Characterization of the 5' to 3' nuclease activity of Thermus aquaticus DNA polymerase on fluorogenic double-stranded probes.

Qiu-Ying Huang, Qingge Li

Molecular and Cellular Probes

DOI

2009

Quadruplex Real-Time PCR Assay for Detection and Identification of Vibrio cholerae O1 and O139 Strains and Determination of Their Toxigenic Potential

Jian-Wei Huang, Yu-Mei Zhu, Hui-Xin Wen, Jiafeng Zhang, Shi-Jie Huang, Jian-Jun Niu, Qingge Li

Applied and Environmental Microbiology

DOI

2009

Lateral flow immunoassay using europium chelate-loaded silica nanoparticles as labels.

Xiaohu Xia, Ye Xu, Xi-Lin Zhao, Qingge Li

Clinical Chemistry

DOI

2008

酶抗体应用实现热启动PCR

林晴，许木于，李庆阁

《中国生物化学与分子生物学报》

2007

荧光置换探针多重实时PCR检测结核杆菌3种耐药突变

张明河，温慧欣，黄建炜，李庆阁，牛建军

《海峡预防医学杂志》

2007

荧光PCR和PFGE在副溶血弧菌食物中毒诊断中的应用研究

兰全学，李庆阁，扈庆华，石晓路，王冰，林一曼

《现代预防医学》

2007

食品污染产单核李斯特菌不同检测方法学评估

王冰，扈庆华，石晓路，李庆阁，郑琳琳，林一曼，张顺祥，林世平，邓辉萍

《中国热带医学》

2007

单管实时PCR快速检验ABO基因型

赵会安，阮力，夏邦勇，栾国彦，李庆阁

《中国法医学杂志》

2007

快速检测副溶血弧菌及其毒力株方法的建立

朱海，张佳峰，李庆阁，赵芳，杨泽，范放，马淑棉

《中华微生物学和免疫学杂志》

2007

实时定量PCR快速检测O1群和O139群霍乱弧菌

张佳峰，朱海，杨泽，唐少冰，李庆阁

《中华微生物学和免疫学杂志》

2007

Dual-Lanthanide-Chelated Silica Nanoparticles as Labels for Highly Sensitive Time-Resolved Fluorometry

Heng Zhang, Ye Xu, Wei Yang, Qingge Li

DOI

2007

Multiple fluorescent labeling of silica nanoparticles with lanthanide chelates for highly sensitive time-resolved immunofluorometric assays.

Ye Xu, Qingge Li

Clinical Chemistry

DOI

2007

Real-time PCR genotyping of aldehyde dehydrogenase-2 using displacing probes.

Yingying Gu, Qingge Li

Clinical Biochemistry

DOI

2007

Real-time PCR detection of multiple lamivudine-resistant mutations with displacing probes in a single tube.

Hui-Xin Wen, Qingge Li

Journal of Clinical Virology

DOI

2007

Identification of 8 foodborne pathogens by multicolor combinational probe coding technology in a single real-time PCR.

Qiu-Ying Huang, Qing-Hua Hu, Qingge Li

Clinical Chemistry

DOI

2007

Multicolor real‐time polymerase chain reaction genotyping of six human platelet antigens using displacing probes

Li Ruan, B. Pei, Qingge Li

Transfusion

DOI

2006

改良分子信标-实时PCR快速检测产单核李斯特菌

王冰，扈庆华，石晓路，李庆阁，郑琳琳，林一曼，贺连华，张顺祥

《中国卫生检验杂志》

2006

改良分子信标-实时PCR快速检测志贺菌

吴平芳，石晓路，郑琳琳，扈庆华，李庆阁，张佳峰，庄志雄，刘小立，张顺祥，王冰，贺连华，林一曼

《中国卫生检验杂志》

2006

多重实时PCR快速同时检测沙门菌和志贺菌

石晓路，扈庆华，张佳峰，李庆阁，王冰，林一曼，庄志雄，刘小立，张顺祥

《中华流行病学杂志》

2006

改良分子信标实时PCR快速检测大肠杆菌O157:H7

贺连华，扈庆华，石晓路，郑琳琳，李庆阁，张佳峰，庄志雄，刘小立，张顺祥，王冰，吴平芳，刘涛

《中国热带医学》

2006

Preparation of His-Tagged Armored RNA Phage Particles as a Control for Real-Time Reverse Transcription-PCR Detection of Severe Acute Respiratory Syndrome Coronavirus

Yangjian Cheng, Jian-Jun Niu, Yongyou Zhang, Jian-Wei Huang, Qingge Li

Journal of Clinical Microbiology

DOI

2006

Preparation of a Chimeric Armored RNA as a Versatile Calibrator for Multiple Virus Assays

Qiu-Ying Huang, Yangjian Cheng, Qi-Wei Guo, Qingge Li

Clinical Chemistry

DOI

2006

[Rapid simultaneous detection of Salmonella and Shigella using modified molecular beacons and real-time PCR].

Xiaolu Shi, Qinghua Hu, Jiafeng Zhang, Qingge Li, Bing Wang, Yi-man Lin, Zhixiong Zhuang, Xiaoli Liu, Shunxiang Zhang

PubMed

2005

实时聚合酶链反应熔解曲线分析检测APC基因突变

郑薇薇，刘忠臣，李庆阁

《中华病理学杂志》

2005

MALDI-TOF-MS结合引物延伸反应检测K-ras基因型方法的建立

刘忠臣，郑薇薇，李庆阁，赵家宏

《中国肿瘤临床》

2005

改良分子信标-双重实时荧光PCR快速检测SARS病毒

扈庆华，刘小立，庄志雄，石晓路，何雅青，刘建军，王冰，刘涛，张永有，李庆阁，赵锦，何建凡，杨洪，房师松，张丹，周俊安

《卫生研究》

2005

ARMS实时PCR和MALDI-TOF-MS进行K-ras基因分型

刘忠臣，郑薇薇，李庆阁

《中国肿瘤》

2005

[Modified molecular beacon-based dual real-time PCR for detection of SARS virus and its application].

Qing-Hua Hu, Xiao-Li Liu, Zhi-Xiong Zhuang, Xiao-Lu Shi, Ya-Qing He, Jian-Jun Liu, Bing Wang, Tao Liu, Yongyou Zhang, Qingge Li, Jin Zhao, Jian-Fan He, Hong Yang, S. Fang, Dan Zhang, Jun'an Zhou

Wei sheng yan jiu = Journal of hygiene research

2005

Quantitative detection of a marine fish iridovirus isolated from large yellow croaker, Pseudosciaena crocea, using a molecular beacon

Xiaowen Wang, Jingqun Ao, Qingge Li, Xinhua Chen

Journal of Virological Methods

DOI

2005

[Detection of APC mutation by real-time polymerase chain reaction and melting curve analysis].

Weiwei Zheng, Zhong-chen Liu, Qingge Li

PubMed

2004

改良分子信标-实时PCR快速检测副溶血弧菌

扈庆华，郑薇薇，石晓路，李庆阁，王冰，庄志雄，刘小立

《现代预防医学》

2004

改良分子信标—实时PCR快速检测霍乱弧菌

扈庆华，郑薇薇，石晓路，叶宝英，李庆阁，王冰，庄志雄，刘小立

《中国热带医学》

2004

双重实时PCR快速同时检测霍乱弧菌和副溶血弧菌

扈庆华，郑薇薇，石晓路，李庆阁，王冰，庄志雄，刘小立，贺连华，吴平芳

《中华微生物学和免疫学杂志》

2004

Real-time PCR genotyping using displacing probes.

Jin-Ping Cheng, Yongyou Zhang, Qingge Li

Nucleic Acids Research

DOI

2003

双链探针同步荧光技术快速筛查C282Y点突变

张永有，李庆阁，栾国彦，梁基选

《遗传》

2002

新型铕络合物用于HBsAg的时间分辨荧光免疫检测

朱艳冰，李庆阁，王桂兰，袁景利

《标记免疫分析与临床》

2002

实时检测限制性内切酶活性的发夹型荧光探针

张永有，李庆阁，梁基选，朱艳冰

Acta Biochimica et Biophysica Sinica

2002

A new class of homogeneous nucleic acid probes based on specific displacement hybridization.

Qingge Li, G. Luan, Qiu-Ping Guo, Ji-Xuan Liang

Nucleic Acids Research

DOI

2000

分子信标探针用于PCR检测对虾白斑杆状病毒

章晓波，徐洵，李庆阁，徐丽美，public.xm.fj.cn

《生物化学与生物物理进展》

2000

分子信标用于结核分枝杆菌的均相荧光PCR检测

李庆阁，梁基选，栾国彦，张洋

《中华微生物学和免疫学杂志》

2000

Molecular Beacon-Based Homogeneous Fluorescence PCR Assay for the Diagnosis of Infectious Diseases

Qingge Li, Ji-Xuan Liang, Luan Guo-Yan, Zhang Yang, Kun Wang

Analytical Sciences

DOI

精选作品

期刊论文

A field-deployable high-resolution SNP genotyping platform for rapid surveillance of Yersinia pestis

Etiologic diagnosis of suspected tuberculous meningitis by multiplex PCR of cerebrospinal fluid

Comparative performance of L1- and E6/E7-targeted HPV genotyping assays based on a unified MeltArray platform

Enhanced diagnosis of tuberculous pleurisy using a multiplex droplet digital PCR assay targeting circulating mycobacterial DNA

Innovative rapid screening for complex BCR-ABL1 kinase domain mutations in TKI-treated leukaemia patients

Identification and quantification of gyrA variants in fluoroquinolone-resistant Mycobacterium tuberculosis in a MeltArray reaction

人乳头瘤病毒分子检测方法研究进展

Molecular serotyping of diarrheagenic Escherichia coli with a MeltArray assay reveals distinct correlation between serotype and pathotype

Multiplex Asymmetric PCR by Combining the Amplification Refractory Mutation System with the Homo-Tag-Assisted Nondimer System

Ability of the MeltPro MTB/PZA Assay to Detect Susceptibility to Pyrazinamide in Rifampin-Resistant Tuberculosis Patients

Quantification of Isoniazid-Heteroresistant Mycobacterium tuberculosis Using Droplet Digital PCR

Highly Sensitive Detection of PIK3CA Mutations by Looping-Out Probes-Based Melting Curve Analysis

Single-tube protocol for culture-independent spoligotyping of Mycobacterium tuberculosis based on MeltArray

Direct identification of pathogens via microbial cellular DNA in whole blood by MeltArray

Epidemiological Insights into the Omicron Outbreak via MeltArray-Assisted Real-Time Tracking of SARS-CoV-2 Variants

Accurate Detection of Multiple Tumor Mutations in Formalin-Fixed Paraffin-Embedded Tissues by Coupling Sequence Artifacts Elimination and Mutation Enrichment With MeltArray

Identification of pneumococcal serotypes with individual recognition of vaccine types by a highly multiplexed real-time PCR-based MeltArray approach

CovidShiny: An Integrated Web Tool for SARS-CoV-2 Mutation Profiling and Molecular Diagnosis Assay Evaluation In Silico

Highly multiplex PCR assays by coupling the 5′-flap endonuclease activity of Taq DNA polymerase and molecular beacon reporters

Qualitative and Quantitative Detection of Multiple Sexually Transmitted Infection Pathogens Reveals Distinct Associations with Cervicitis and Vaginitis

Accessible and Adaptable Multiplexed Real-Time PCR Approaches to Identify SARS-CoV-2 Variants of Concern

A Novel Molecular Method for Simultaneous Identification of Vibrio parahaemolyticus 57 K-Serogroups Using Probe Melting Curve Analysis

Genotypic diversity of Mycobacterium tuberculosis isolates and its association with drug-resistance status in Xinjiang, China.

Segmental duplication as potential biomarkers for non-invasive prenatal testing of aneuploidies

Y染色体AZF基因微缺失在诊断苏南地区男性不育患者中的研究

锁核酸修饰探针熔解曲线分析在Kras基因突变检测中的应用

基于多色探针熔解曲线分析技术的华法林个体化用药相关基因多态性快速检测方法

结核分枝杆菌新型间隔区寡核甘酸分型技术临床应用价值研究

Multiplex ligation reaction based on probe melting curve analysis: a pragmatic approach for the identification of 30 common Salmonella serovars

Profile of MeltPro® HPV test for human papillomavirus genotyping and cervical precancer screening

Simultaneous Identification of Clinically Common Vibrio parahaemolyticus Serotypes Using Probe Melting Curve Analysis

Chinese newborn screening for the incidence of G6PD deficiency and variant of G6PD gene from 2013 to 2017

多色探针熔解曲线法在卡马西平不良反应相关基因检测中的临床评价

多色探针熔解曲线法应用于别嘌呤醇不良反应相关基因HLA-B* 58∶01的检测

Correction to: Spectrum of PAH gene variants among a population of Han Chinese patients with phenylketonuria from northern China

Probe based melting curve analysis in anti-HBV drug resistance gene mutation detection

McSpoligotyping, a One-Step Melting Curve Analysis-Based Protocol for Spoligotyping of Mycobacterium tuberculosis

Rapid Identification of Clinically Relevant Mycobacterium Species by Multicolor Melting Curve Analysis

Simultaneous Genotyping of α-Thalassemia Deletional and Nondeletional Mutations by Real-Time PCR-Based Multicolor Melting Curve Analysis.

Spectrum of PAH gene variants among a population of Han Chinese patients with phenylketonuria from northern China

Highly Sensitive Detection of Isoniazid Heteroresistance in Mycobacterium tuberculosis by DeepMelt Assay

Rapid and Reliable Detection of Nonsyndromic Hearing Loss Mutations by Multicolor Melting Curve Analysis

A comparison of the MeltPro® HPV Test with the Cobas® HPV Test for detecting and genotyping 14 high-risk human papillomavirus types

Review: Molecular detection of extended spectrum-β-lactamase- and carbapenemase-producing Enterobacteriaceae in a clinical setting.

Simultaneous Genotyping of a-Thalassemia Deletional and Nondeletional Mutations by

Simultaneous Identification of Ten Bacterial Pathogens Using the Multiplex Ligation Reaction Based on the Probe Melting Curve Analysis

厦门地区遗传性耳聋流行病学调查

Rapid detection of G6PD mutations by multicolor melting curve analysis.

Rapid detection of non-deletional mutations causing α-thalassemia by multicolor melting curve analysis

Spoligotyping of Mycobacterium tuberculosis Complex Isolates by Use of Ligation-Based Amplification and Melting Curve Analysis

A strip array for spoligotyping of Mycobacterium tuberculosis complex isolates.

Detection of Anti-Hepatitis B Virus Drug Resistance Mutations Based on Multicolor Melting Curve Analysis

大肠埃希菌和肺炎克雷伯菌质粒型AmpC酶基因型的检测分析

探针熔解曲线法快速检测结核分枝杆菌注射类二线药耐药突变

Rapid detection of HCV genotyping 1a, 1b, 2a, 3a, 3b and 6a in a single reaction using two-melting temperature codes by a real-time PCR-based assay

Heptaplex PCR melting curve analysis for rapid detection of plasmid-mediated AmpC β-lactamase genes.

Evaluation of the MeltPro TB/STR assay for rapid detection of streptomycin resistance in Mycobacterium tuberculosis.

Multicolor Melting Curve Analysis-Based Multilocus Melt Typing of Vibrio parahaemolyticus

[Development of a rapid molecular typing method for Vibrio cholerae using melting curve-based multilocus melt typing].

厦门地区非缺失型α-地中海贫流行病学调查

Saliva as a sampling source for the detection of leukemic fusion transcripts

Rapid genetic typing of diarrheagenic Escherichia coli using a two-tube modified molecular beacon based multiplex real-time PCR assay and its clinical application

Rapid Detection of Isoniazid Resistance in Mycobacterium tuberculosis Isolates by Use of Real-Time-PCR-Based Melting Curve Analysis

Fluorescent probe-based lateral flow assay for multiplex nucleic acid detection.

Real-Time Bidirectional Pyrophosphorolysis-Activated Polymerization for Quantitative Detection of Somatic Mutations

Deafness susceptibility gene mutation detection kit as well as preparation method and application thereof

荧光PCR探针熔解曲线法检测结核分枝杆菌耐异烟肼突变

用探针熔解曲线法检测急性髓细胞白血病c-kit基因突变

A highly sensitive europium nanoparticle-based lateral flow immunoassay for detection of chloramphenicol residue

Combination of fluorescence color and melting temperature as a two-dimensional label for homogeneous multiplex PCR detection

Natural phage nanoparticle-mediated real-time immuno-PCR for ultrasensitive detection of protein marker.

A Modified Molecular Beacons–Based Multiplex Real-Time PCR Assay for Simultaneous Detection of Eight Foodborne Pathogens in a Single Reaction and Its Application

PCR-探针熔解分析法检测结核分枝杆菌利福平耐药性的临床应用

急性白血病MLL融合基因新检测方法的建立和应用

Application of europium(III) chelates-bonded silica nanoparticle in time-resolved immunofluorometric detection assay for human thyroid stimulating hormone.

Simultaneous Detection, Genotyping, and Quantification of Human Papillomaviruses by Multicolor Real-Time PCR and Melting Curve Analysis

Human Papillomaviruses by Multicolor Real-Time PCR and

Molecular diagnosis of β-thalassemia