百晓学者学者目录

胡欣

副教授、博导、教授、硕导、讲师，青岛大学

精选作品

期刊论文

2023

In vivo CRISPR screens identify RhoV as a pro‐metastasis factor of triple‐negative breast cancer

M. Jin, Yue Gong, P. Ji, Xin Hu, Z. Shao

Cancer Science

DOI

2023

Regulation of ERα-dependent breast cancer metastasis by a miR-29a signaling

Jin-Hui Lu, Qian Zhao, Yuefan Guo, Danni Li, Heying Xie, Cui-Cui Liu, Xin Hu, Suling Liu, Zhaoyuan Hou, Xun-Bin Wei, De-You Zheng, R. Pestell, Zuo-Ren Yu

Journal of experimental & clinical cancer research : CR

DOI

2023

The overall survival analysis of FUTURE-C-PLUS: Combination of famitinib with camrelizumab plus nab-paclitaxel as first-line treatment for advanced, immunomodulatory triple-negative breast cancer—An open-label, single-arm, phase 2 trial.

Li Chen, Zhi-Min Shao, Zhong-Hua Wang, Wentao Yang, Yi-Zhou Jiang, Song-Yang Wu, Jiong Wu, Gen-Hong Di, Guang-Yu Liu, Ke-Da Yu, Lei Fan, Jun-Jie Li, Yi-Feng Hou, Zhen Hu, Can-Ming Chen, Xiao-Yan Huang, A. Cao, Xin Hu, Xiaoyu Zhu

Journal of Clinical Oncology

DOI

2023

An in vivo CRISPR screen identifies that SNRPC promotes triple-negative breast cancer progression.

Xunxi Lu, Wen-Xiao Yang, Yuchen Pei, Hong Luo, Xiaoguang Li, Yun-Jin Wang, Guo-Liang Zhang, Hong Ling, Zhiming Shao, Xin Hu

Cancer Research

DOI

2023

FUTURE-SUPER: A randomized, subtyping-based umbrella phase II trial for first-line treatment of metastatic triple-negative breast cancer.

Zhi-Min Shao, Lei Fan, Ma Linxiaoxi, Song-Yang Wu, Li Chen, Xi-Yu Liu, Wen-Juan Zhang, Xin Hu, Yi-Zhou Jiang, Zhong-Hua Wang, Huajun Li

Journal of Clinical Oncology

DOI

2022

Abstract P2-14-04: Updated data from FUTURE-C-PLUS: Combination of famitinib with camrelizumab plus nab-paclitaxel as first-line treatment for advanced, immunomodulatory triple-negative breast cancer, an open-label, single-arm, phase 2 trial

Li Chen, Yi-Zhou Jiang, Song-Yang Wu, Jiong Wu, Gen-Hong Di, Guang-Yu Liu, K. Yu, Lei Fan, Jun-Jie Li, Yi-Feng Hou, Zhen Hu, Can-Ming Chen, Xiao-Yan Huang, A. Cao, Xin Hu, Shen Zhao, Xiao-Yan Ma, Xiaoyu Zhu, J. Zou, Wentao Yang, Zhong-Hua Wang, Z. Shao

Cancer Research

DOI

2022

HNRNPU promotes the progression of triple-negative breast cancer via RNA transcription and alternative splicing mechanisms

Bo-Yue Han, Zhe-Bin Liu, Xin Hu, Hong Ling

Cell Death and Disease

DOI

2022

CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4‐Fatty Acid β‐Oxidation Pathway

Hong-Quan Li, Junjiao Song, Yifei He, Yi-Zhen Liu, Zhen Liu, Wei-Li Sun, Weiguo Hu, Qun-Ying Lei, Xin Hu, Zhiao Chen, Xiang-Huo He

Advancement of science

DOI

2022

The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer.

Hai Wang, Xing-Yu Rong, Gan Zhao, Yi-Fan Zhou, Yi Xiao, Ding Ma, Xi Jin, Yonglin Wu, Yuchen Yan, Hao Yang, Yuan Zhou, Manning Qian, C. Niu, Xin Hu, Da-Qiang Li, Qingyun Liu, Yumei Wen, Yi-Zhou Jiang, Chao Zhao, Z. Shao

Cell Metabolism

DOI

2022

Liquid Biopsy and Tissue Biopsy Comparison with Digital PCR and IHC/FISH for HER2 Amplification Detection in Breast Cancer Patients

Suo-Hong Xie, Yan Wang, Z. Gong, Yuan Li, Wen-Tao Yang, Guang-Yu Liu, Jian-Wei Li, Xin Hu, Yan-Chun Wang, Y. Tong, P. Yuan, Yiran Si, Yi Kang, Yong Mao, X. Qi, Yan-Kui Liu, Jia-Jia Ou, Zhao-Liang Li, Xin Pan, Zhao-Ying Lv, Kavanaugh Kaji, Lin Guo, R. Lu

Journal of Cancer

DOI

2022

RNA binding protein POP7 regulates ILF3 mRNA stability and expression to promote breast cancer progression

Yan-Ni Huang, Yi-Zi Zheng, L. Yao, Feng Qiao, Yi-Feng Hou, Xin Hu, Da-Qiang Li, Z. Shao

Cancer Science

DOI

2022

Identification of a novel signature with prognostic value in triple-negative breast cancer through clinico-transcriptomic analysis

Chao Chen, Cai-Jin Lin, Si-Yuan Li, Xin Hu, Z. Shao

Annals of Translational Medicine

DOI

2022

Combined angiogenesis and PD-1 inhibition for immunomodulatory TNBC: concept exploration and biomarker analysis in the FUTURE-C-Plus trial

Song-Yang Wu, Ying Xu, Li Chen, Lei Fan, Xiao-Yan Ma, Shen Zhao, Xiao-Qing Song, Xin Hu, Wen-tao Yang, W. Chai, Xiao-Mao Guo, Xi-Zi Chen, Yan-Hui Xu, Xiao-yu Zhu, J. Zou, Zhong-Hua Wang, Yi-Zhou Jiang, Z. Shao

Molecular Cancer

DOI

2022

In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer

P. Ji, Yue Gong, M. Jin, Huai-Liang Wu, Lin-Wei Guo, Yuchen Pei, Wenxian Chai, Yi-Zhou Jiang, Yin Liu, Xiao-Yan Ma, Gen-Hong Di, Xin Hu, Z. Shao

Science Advances

DOI

2022

Famitinib with Camrelizumab and Nab-Paclitaxel for Advanced Immunomodulatory Triple-Negative Breast Cancer (FUTURE-C-Plus): An Open-Label, Single-Arm, Phase II Trial

Li Chen, Yi-Zhou Jiang, Song-Yang Wu, Jiong Wu, Gen-Hong Di, Guang-Rong Liu, Ke-Da Yu, Lei Fan, Jun-Jie Li, Yi-Feng Hou, Zhen Hu, Can-Ming Chen, Xiao-Yan Huang, A. Cao, Xin Hu, Shen Zhao, Xiao-yan Ma, Ying Xu, Xiang-Jie Sun, Wenqing Chai, Xiao-Mao Guo, Xi-Zi Chen, Yan-Hui Xu, Xiao-yu Zhu, J. Zou, Wen-tao Yang, Zhong-Hua Wang, Z. Shao

Clinical Cancer Research

DOI

2022

The safety, tolerability, and preliminary antitumor activity of sitravatinib plus tislelizumab in patients with locally recurrent or metastatic triple-negative breast cancer.

Lei Fan, Xi-Yu Liu, Xi Jin, Yunsong Yang, Li Chen, Xin Hu, Zhong-Hua Wang, Yi-Zhou Jiang, Z. Shao

Journal of Clinical Oncology

DOI

2022

Comprehensive metabolomics expands precision medicine for triple-negative breast cancer

Yi Xiao, Ding Ma, Yun-Song Yang, Fan Yang, Jianlong Ding, Yue Gong, Linbailu Jiang, Li-Ping Ge, Song-Yang Wu, Qiang Z. Yu, Qing Zhang, F. Bertucci, Qiuzhuang Sun, Xin Hu, Da-Qiang Li, Z. Shao, Yi-Zhou Jiang

Cell Research

DOI

2022

Identification and validation of a prognostic risk model based on caveolin family genes for breast cancer

Q. Tang, Shu-Rui Wang, Z. Di, Huimin Li, Kai-Liang Xu, Xin Hu, Maojun Di

Frontiers in Cell and Developmental Biology

DOI

2021

GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer

Jin-Li Wei, Siyi Wu, Yun-Song Yang, Yi Xiao, Xi Jin, Xiao-En Xu, Xin Hu, Da-Qiang Li, Yi-Zhou Jiang, Z. Shao

Journal for ImmunoTherapy of Cancer

DOI

2021

Bulk and Single-cell Transcriptome Profiling Reveal the Metabolic Heterogeneity in Human Breast Cancers.

Tian-Jian Yu, Ding Ma, Ying-Ying Liu, Yi Xiao, Yue Gong, Yi-Zhou Jiang, Z. Shao, Xin Hu, Gen-Hong Di

Molecular Therapy

DOI

2021

Combination of famitinib with camrelizumab plus nab-paclitaxel as first-line treatment for patients with immunomodulatory advanced triple-negative breast cancer (FUTURE-C-PLUS): A prospective, single-arm, phase 2 study.

Li Chen, Zhi-Min Shao, Zhong-Hua Wang, Wentao Yang, Yi-Zhou Jiang, J. Zou, Jiong Wu, Gen-Hong Di, Guang-Yu Liu, Ke-Da Yu, Lei Fan, Jun-Jie Li, Yi-Feng Hou, Zhen Hu, Can-Ming Chen, Xiao-Yan Huang, A. Cao, Xin Hu, Song-Yan Wu, Shen Zhao

DOI

2021

Clinicopathological Characteristics and Survival Outcomes of Mammary Paget’s Disease: A Retrospective Study Based on a Chinese Population

Bo-Yue Han, Xiao-Li Xu, Xiuqin Zhu, Xiangrui Han, Xin Hu, Hong Ling

Cancer Management and Research

DOI

2021

Large‐scale genomic sequencing reveals adaptive opportunity of targeting mutated‐PI3Kα in early and advanced HER2‐positive breast cancer

Lin-Wei Guo, Xiaoguang Li, Yun-Song Yang, Xunxi Lu, Xiangming Han, G. Lang, Li Chen, Z. Shao, Xin Hu

Clinical and Translational Medicine

DOI

2021

Insights Into the Impacts of BRCA Mutations on Clinicopathology and Management of Early-Onset Triple-Negative Breast Cancer

Fu-Gui Ye, Min He, Liang Huang, G. Lang, Xin Hu, Z. Shao, Gen-Hong Di, A. Cao

Frontiers in Oncology

DOI

2021

PDSS1-Mediated Activation of CAMK2A-STAT3 Signaling Promotes Metastasis in Triple-Negative Breast Cancer

Tian-Jian Yu, Ying-Ying Liu, Xiaoguang Li, B. Lian, Xunxi Lu, Xi Jin, Z. Shao, Xin Hu, Gen-Hong Di, Yi-Zhou Jiang

Cancer Research

DOI

2021

Erratum: KCNN4 induces multiple chemoresistance in breast cancer by regulating BCL2A1.

Peiyang Lin, Junjing Li, Fu-Gui Ye, Wenfen Fu, Xin Hu, Z. Shao, Chuan-Gui Song

American Journal of Cancer Research

2021

A Risk Stratification Model for Predicting Survival in Breast Cancer Patients With Lung Metastasis: A Study of the SEER Database and A Chinese Cohort

Xiang Han, Yuchen Pei, Yun-Jin Wang, Xiaoguang Li, Xunxi Lu, Lin-Wei Guo, Bo-Yue Han, Yue Gong, Hong Ling, Xin Hu

DOI

2021

MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer

Siyi Wu, Yi Xiao, Jin-Li Wei, Xiao-En Xu, Xi Jin, Xin Hu, Da-Qiang Li, Yi-Zhou Jiang, Z. Shao

Journal for ImmunoTherapy of Cancer

DOI

2020

Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer

Xiuzhi Zhu, Li Chen, Binhao Huang, Xiaoguang Li, Liu Yang, Xin Hu, Yi-Zhou Jiang, Z. Shao, Zhong-Hua Wang

Journal of experimental & clinical cancer research : CR

DOI

2020

Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer

B. Lian, Yuchen Pei, Yi-Zhou Jiang, Meng-zhu Xue, Da-Qiang Li, Xiaoguang Li, Yi-Zi Zheng, Xi-Yu Liu, Feng Qiao, Wei-Li Sun, Hong Ling, Min He, L. Yao, Xin Hu, Z. Shao

Theranostics

DOI

2020

The Burden and Trends of Breast Cancer From 1990 to 2017 at the Global, Regional, and National Levels: Results From the Global Burden of Disease Study 2017

P. Ji, Yue Gong, M. Jin, Xin Hu, Gen-Hong Di, Z. Shao

Frontiers in Oncology

DOI

2020

Acetylation of MORC2 by NAT10 regulates cell-cycle checkpoint control and resistance to DNA-damaging chemotherapy and radiotherapy in breast cancer

Hong-Yi Liu, Ying-Ying Liu, Fan Yang, Lin Zhang, Fang-Lin Zhang, Xin Hu, Z. Shao, Da-Qiang Li

Nucleic Acids Research

DOI

2020

Nomogram for Predicting Breast Cancer-Specific Mortality of Elderly Women with Breast Cancer

Xunxi Lu, Xiaoguang Li, Hong Ling, Yue Gong, Lin-Wei Guo, Min He, He-Fen Sun, Xin Hu

Medical Science Monitor

DOI

2020

KCNN4 induces multiple chemoresistance in breast cancer by regulating BCL2A1.

Peiyang Lin, Junjing Li, Fu-Gui Ye, Wenfen Fu, Xin Hu, Z. Shao, Chuan-Gui Song

American Journal of Cancer Research

2020

Clinical features and survival of pregnancy-associated breast cancer: a retrospective study of 203 cases in China

Bo-Yue Han, Xiaoguang Li, Haiyun Zhao, Xin Hu, Hong Ling

BMC Cancer

DOI

2020

Molecular features and functional implications of germline variants in triple-negative breast cancer.

Ding Ma, Si-Yu Chen, Jin-Xiao Ren, Yuchen Pei, Cong Jiang, Shen Zhao, Yi Xiao, Xiao-En Xu, Guang-Yu Liu, Xin Hu, Xiao-Zhen Liang, Ke-Da Yu, Da-Qiang Li, Yi-Zhou Jiang, Z. Shao

Journal of the National Cancer Institute

DOI

2020

Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial

Yi-Zhou Jiang, Yin Liu, Yi Xiao, Xin Hu, Lin Jiang, Wen-Jia Zuo, Ding Ma, Jiahan Ding, Xiaoyu Zhu, J. Zou, C. Verschraegen, D. Stover, V. Kaklamani, Zhong-Hua Wang, Z. Shao

Cell Research

DOI

2020

Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets.

Yue Gong, P. Ji, Yun-Song Yang, S. Xie, Tian-Jian Yu, Yi Xiao, M. Jin, Ding Ma, Lin-Wei Guo, Yuchen Pei, W. Chai, Da-Qiang Li, F. Bai, F. Bertucci, Xin Hu, Yi-Zhou Jiang, Z. Shao

Cell Metabolism

DOI

2020

Outcomes and risk of subsequent breast events in breast‐conserving surgery patients with BRCA1 and BRCA2 mutation

Fu-Gui Ye, Liang Huang, G. Lang, Xin Hu, Gen-Hong Di, Z. Shao, A. Cao

Cancer Medicine

DOI

2020

Characterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing

G. Lang, Yi-Zhou Jiang, Jin-Xiu Shi, Fan Yang, Xiaoguang Li, Yuchen Pei, Chen-hui Zhang, Ding Ma, Yi Xiao, Pengchen Hu, Hai Wang, Yun-Song Yang, Lin-Wei Guo, Xunxi Lu, Meng-zhu Xue, Peng Wang, A. Cao, Hong Ling, Zhong-Hua Wang, Ke-Da Yu, Gen-Hong Di, Da-Qiang Li, Yun-Jin Wang, Ying Yu, Le-Ming Shi, Xin Hu, Wei Huang, Z. Shao

Nature Communications

DOI

2020

Dissecting the heterogeneity of the alternative polyadenylation profiles in triple-negative breast cancers

Lei Wang, G. Lang, Meng-zhu Xue, Liu Yang, Li Chen, L. Yao, Xiaoguang Li, Peng Wang, Xin Hu, Z. Shao

Theranostics

DOI

2020

Abstract P2-08-16: The burden and trends of breast cancer from 1990 to 2017 at the global, regional, and national level: Results from the global burden of disease study 2017

Yue Gong, P. Ji, Xin Hu, Z. Shao

Poster Session Abstracts

DOI

2020

Multiple cancer susceptible genes sequencing in BRCA-negative breast cancer with high hereditary risk

G. Lang, Jin-Xiu Shi, Liang Huang, A. Cao, Chen-hui Zhang, Chuan-Gui Song, Zhi-Gang Zhuang, Xin Hu, Wei Huang, Z. Shao

Annals of Translational Medicine

DOI

2020

Abstract P4-09-01: Clinical sequencing characterizes the genomic landscape and actionable mutations of Chinese breast cancer

G. Lang, Jin-Xiu Shi, Yi-Zhou Jiang, Xiaoguang Li, Yuchen Pei, Fang-Lin Zhang, Chen-hui Zhang, Ding Ma, Yi Xiao, Ke-Da Yu, Pengchen Hu, M. Jin, Hai Wang, Yun-Song Yang, Xuan Luo, Qi Hong, Feng Qiao, Wei-Li Sun, Meng-zhu Xue, Shiping Li, A. Cao, Zhong-Hua Wang, Jia-Xin Zhang, Gen-Hong Di, Peng Wang, Da-Qiang Li, Xin Hu, Wei Huang, Z. Shao

Poster Session Abstracts

DOI

2020

Association between socioeconomic factors at diagnosis and survival in breast cancer: A population‐based study

P. Ji, Yue Gong, Changchuan Jiang, Xin Hu, Gen-Hong Di, Z. Shao

Cancer Medicine

DOI

2019

Integration of whole‐genome sequencing and functional screening identifies a prognostic signature for lung metastasis in triple‐negative breast cancer

G. Xie, Haiyuan Yang, Ding Ma, Yi-Hua Sun, Hai-Quan Chen, Xin Hu, Yi-Zhou Jiang, Z. Shao

International Journal of Cancer

DOI

2019

High-Throughput Screening and Functional Validation Reveals Involvement of the KCNN4-BCL2A1 Axis in Breast Cancer Multidrug Chemoresistance

Pei-Yang Lin, Junjing Li, Fu-Gui Ye, Wenfen Fu, Xin Hu, Z. Shao, Chuan-Gui Song

Social Science Research Network

DOI

2019

Unveiling novel targets of paclitaxel resistance by single molecule long-read RNA sequencing in breast cancer

B. Lian, Xin Hu, Z. Shao

Scientific Reports

DOI

2019

Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies.

Yi-Zhou Jiang, Ding Ma, Chen Suo, Jinxiu Shi, Meng-zhu Xue, Xin Hu, Yi Xiao, Ke-Da Yu, Yi-Rong Liu, Ying Yu, Yuan-Ting Zheng, Xiangnan Li, Chen-hui Zhang, Pengchen Hu, Jing Zhang, Qi Hua, Ji-Yang Zhang, Wanwan Hou, Luyao Ren, Ding Bao, Bingying Li, Jingcheng Yang, L. Yao, Wen-Jia Zuo, Shen Zhao, Yue Gong, Yifan Ren, Ya-Xin Zhao, Yun-Song Yang, Zhenmin Niu, Zhi-Gang Cao, D. Stover, C. Verschraegen, V. Kaklamani, A. Daemen, J. Benson, K. Takabe, F. Bai, Da-Qiang Li, Peng Wang, Le-Ming Shi, Wei Huang, Z. Shao

Cancer Cell

DOI

2019

Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells

Yifei Zhu, Mingxu Xie, Zhaoyue Meng, L. Leung, F. Chan, Xin Hu, K. Chi, Cuiling Liu, Xiao-Qiang Yao

Oncogene

DOI

2019

Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer

Yi Xiao, Ding Ma, Shen Zhao, Chen Suo, Jinxiu Shi, Meng-zhu Xue, Miao Ruan, Hai Wang, Jing-Jing Zhao, Qin Li, Peng Wang, Le-Ming Shi, Wen-tao Yang, Wei Huang, Xin Hu, Ke-Da Yu, Sheng-Lin Huang, F. Bertucci, Yi-Zhou Jiang, Z. Shao

Clinical Cancer Research

DOI

2019

Neddylation Inactivation Facilitates FOXO3a Nuclear Export to Suppress Estrogen Receptor Transcription and Improve Fulvestrant Sensitivity

Xiao-Qing Jia, Chun-Jie Li, Lihui Li, Xiaoli Liu, Li-Sha Zhou, Wen-Juan Zhang, Shuai-Shuai Ni, Yunying Lu, Li Chen, L. Jeong, Jin-Ha Yu, Ying-Jian Zhang, Jian-Ping Zhang, Si-Min He, Xin Hu, He-Fen Sun, Ke-Da Yu, Guang-Yu Liu, Hu Zhao, Yan-Mei Zhang, L. Jia, Z. Shao

Clinical Cancer Research

DOI

2019

High expression of metabolic enzyme PFKFB4 is associated with poor prognosis of operable breast cancer

L. Yao, Lei Wang, Zhi-Gang Cao, Xin Hu, Z. Shao

Cancer Cell International

DOI

2019

Survival analysis of pregnancy-associated breast cancer: multiparous women might have better outcomes

Bo-Yue Han, Xiaoguang Li, Haiyun Zhao, Xin Hu, Hong Ling

DOI

2019

Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers

Dai-Song Wang, Xin Hu, Chun-Ye Liu, Ying-bo Jia, Yiqin Bai, Cheguo Cai, Jingqiang Wang, Lanyue Bai, Ruikai Yang, Chang-Dong Lin, Yi-Rong Liu, Shan Li, Feng Qiao, L. Yao, Li Chen, G. Ge, Hai Jiang, Dianfan Li, Lin Li, Jianfeng Chen, Z. Shao, Y. Zeng

Cell Research

DOI

2019

Modified lymph node ratio improves the prognostic predictive ability for breast cancer patients compared with other lymph node staging systems

M. Jin, Yue Gong, Yu-Cheng Pei, P. Ji, Xin Hu, Z. Shao

Breast

DOI

2019

The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation

Xi Jin, Xiao-En Xu, Yi-Zhou Jiang, Yi-Rong Liu, Wei Sun, Ya-Jie Guo, Yifan Ren, Wen-Jia Zuo, Xin Hu, Sheng-Lin Huang, Hong-Jie Shen, Fei Lan, Yunsong He, Guo-Xing Hu, Gen-Hong Di, Xiang-Huo He, Da-Qiang Li, Suling Liu, Ke-Da Yu, Z. Shao

Science Advances

DOI

2018

Integrative 3' Untranslated Region-Based Model to Identify Patients with Low Risk of Axillary Lymph Node Metastasis in Operable Triple-Negative Breast Cancer.

Lei Wang, Xin Hu, Peng Wang, Z. Shao

The Oncologist

DOI

2018

Author Correction: Impact of hormone receptor status and distant recurrence-free interval on survival benefits from trastuzumab in HER2-positive metastatic breast cancer

Haiyuan Yang, Ding Ma, Yi-Rong Liu, Xin Hu, Jian Zhang, Zhong-Hua Wang, Gen-Hong Di, Xi-Chun Hu, Z. Shao

Scientific Reports

DOI

2018

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients

Li Chen, Liu Yang, L. Yao, X. Kuang, Wen-Jia Zuo, Shan Li, Feng Qiao, Yi-Rong Liu, Zhi-Gang Cao, Shu-Ling Zhou, Xiao-Yan Zhou, Wen-tao Yang, Jin-Xiu Shi, Wei Huang, Xin Hu, Z. Shao

Nature Communications

DOI

2018

Nomogram for predicting preoperative lymph node involvement in patients with invasive micropapillary carcinoma of breast: a SEER population-based study

Fu-Gui Ye, Chen Xia, Ding Ma, Pei-Yang Lin, Xin Hu, Z. Shao

BMC Cancer

DOI

2018

Survival following breast-conserving therapy is equal to that following mastectomy in young women with early-stage invasive lobular carcinoma.

Tian-Jian Yu, Ying-Ying Liu, Xin Hu, Gen-Hong Di

European Journal of Surgical Oncology

DOI

2018

Elevated miR-301a expression indicates a poor prognosis for breast cancer patients

Jingyan Zheng, Yan-Ni Huang, L. Yao, Yi-Rong Liu, Sheng Liu, Xin Hu, Zhe-Bin Liu, Z. Shao

Scientific Reports

DOI

2018

Development and validation of nomograms for predicting overall and breast cancer-specific survival among patients with triple-negative breast cancer

Lin-Wei Guo, Linbailu Jiang, Yue Gong, H. Zhang, Xiaoguang Li, Min He, Wei-Li Sun, Hong Ling, Xin Hu

Cancer Management and Research

DOI

2018

MicroRNA‐493 is a prognostic factor in triple‐negative breast cancer

L. Yao, Yi-Rong Liu, Zhi-Gang Cao, Junjing Li, Yan-Ni Huang, Xin Hu, Z. Shao

Cancer Science

DOI

2018

PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression.

Yi-Zi Zheng, Meng-zhu Xue, Hong-Jie Shen, Xiaoguang Li, Ding Ma, Yue Gong, Yi-Rong Liu, Feng Qiao, Hong-Yan Xie, B. Lian, Wei-Li Sun, Haiyun Zhao, L. Yao, Wen-Jia Zuo, Da-Qiang Li, Peng Wang, Xin Hu, Z. Shao

Cancer Research

DOI

2018

CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription

Sheng Huang, Y. Chi, Yi Qin, Ziliang Wang, B. Xiu, Yong-Hui Su, R. Guo, Liang Guo, He-Fen Sun, Chu-Jia Zeng, Shu-Ling Zhou, Xin Hu, Sheng Liu, Z. Shao, Zhao-ming Wu, W. Jin, Jiong Wu

Theranostics

DOI

2018

Incidence and prognostic factors of patients with synchronous liver metastases upon initial diagnosis of breast cancer: a population-based study

Haiyun Zhao, Yue Gong, Fu-Gui Ye, Hong Ling, Xin Hu

Cancer Management and Research

DOI

2018

Incidence proportions and prognosis of breast cancer patients with bone metastases at initial diagnosis

Yue Gong, Jing Zhang, P. Ji, Hong Ling, Xin Hu, Z. Shao

Cancer Medicine

DOI

2018

Racial/ethnic differences in the outcomes of patients with metastatic breast cancer: contributions of demographic, socioeconomic, tumor and metastatic characteristics

Jin-Xiao Ren, Yue Gong, Hong Ling, Xin Hu, Z. Shao

Breast Cancer Research and Treatment

DOI

2018

Development and Validation of Nomograms for Predicting Overall and Breast Cancer–Specific Survival in Young Women with Breast Cancer: A Population-Based Study

Yue Gong, P. Ji, Wei Sun, Yi-Zhou Jiang, Xin Hu, Z. Shao

Translational Oncology

DOI

2018

No survival improvement of contralateral prophylactic mastectomy among women with invasive lobular carcinoma

Tian-Jian Yu, Ying-Ying Liu, Xin Hu, Gen-Hong Di

Journal of Surgical Oncology

DOI

2017

IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer

Dong Wang, Jiahui Xu, Bingjie Liu, Xueyan He, Lei Zhou, Xin Hu, Feng Qiao, An-Li Zhang, Xiao-Jun Xu, Hua-Feng Zhang, M. Wicha, Li-Xing Zhang, Z. Shao, Suling Liu

Cell Death and Differentiation

DOI

2017

Impact of hormone receptor status and distant recurrence-free interval on survival benefits from trastuzumab in HER2-positive metastatic breast cancer

Haiyuan Yang, Ding Ma, Yi-Rong Liu, Xin Hu, Jian Zhang, Zhong-Hua Wang, Gen-Hong Di, Xi-Chun Hu, Z. Shao

Scientific Reports

DOI

2017

Impact of molecular subtypes on metastatic breast cancer patients: a SEER population-based study

Yue Gong, Yi-Rong Liu, P. Ji, Xin Hu, Z. Shao

Scientific Reports

DOI

2017

High expression of PLA2G16 is associated with a better prognosis in HER2-positive breast cancer.

Xueli Yang, Zheng-Quan Zhang, Xiao-Qing Jia, Yanqin Zhang, Tianyang Mu, Bingzheng Zhou, Lin Li, D. Fu, Xin Hu, S. Xiong

Journal of Thoracic Disease

DOI

2017

The spectrum of BRCA mutations and characteristics of BRCA‐associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next‐generation sequencing

G. Lang, Jin-Xiu Shi, Xin Hu, Chen-hui Zhang, Shan Ling, Chuan-Gui Song, Zhi-Gang Zhuang, A. Cao, Hong Ling, Ke-Da Yu, Shan Li, Meng-Hong Sun, Xiao-Yan Zhou, Wei Huang, Z. Shao

International Journal of Cancer

DOI

2017

Protein C receptor stimulates multiple signaling pathways in breast cancer cells

Dai-Song Wang, Chun-Ye Liu, Jingqiang Wang, Yingying Jia, Xin Hu, Hai Jiang, Z. Shao, Y. Zeng

Journal of Biological Chemistry

DOI

2016

Dual Characteristics of Novel HER2 Kinase Domain Mutations in Response to HER2-Targeted Therapies in Human Breast Cancer

Wen-Jia Zuo, Yi-Zhou Jiang, Yu-Jie Wang, Xiao-En Xu, Xin Hu, Guang-Yu Liu, Jiong Wu, Gen-Hong Di, Ke-Da Yu, Z. Shao

Clinical Cancer Research

DOI

2016

SSBP1 Suppresses TGFβ-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling.

Hong-lin Jiang, He-Fen Sun, Shuiping Gao, Liang-Dong Li, Sheng Huang, Xin Hu, Sheng Liu, Jiong Wu, Z. Shao, W. Jin

Cancer Research

DOI

2016

Genetic evaluation of BRCA1-A complex genes with triple-negative breast cancer susceptibility in Chinese women

Hong Ling, Shan Li, Yang Wu, Yi-Zi Zheng, Feng Qiao, L. Yao, Zhi-Gang Cao, Fu-Gui Ye, Jiong Wu, Xin Hu, Bin Wang, Z. Shao

OncoTarget

DOI

2016

Comprehensive transcriptome analysis identifies novel molecular subtypes and subtype-specific RNAs of triple-negative breast cancer

Yi-Rong Liu, Yi-Zhou Jiang, Xiao-En Xu, Ke-Da Yu, Xi Jin, Xin Hu, Wen-Jia Zuo, S. Hao, Jiong Wu, Guang-Yu Liu, Gen-Hong Di, Da-Qiang Li, Xiang-Huo He, Wei-Guo Hu, Z. Shao

Breast Cancer Research

DOI

2016

Positive expression of miR-361-5p indicates better prognosis for breast cancer patients.

Zhi-Gang Cao, Yan-Ni Huang, L. Yao, Yi-Rong Liu, Xin Hu, Yi-Feng Hou, Z. Shao

Journal of Thoracic Disease

DOI

2016

The BMP inhibitor DAND5 in serum predicts poor survival in breast cancer

Y. Chi, L. Yao, Xin Hu, Sheng Huang, N. Huang, Shan Li, Z. Shao, Jiong Wu

OncoTarget

DOI

2016

Clinicopathological characteristics of patients with HER2-positive breast cancer and the efficacy of trastuzumab in the People’s Republic of China

P. Zhou, Yi-Zhou Jiang, Xin Hu, Wei Sun, Yi-Rong Liu, Fang Liu, Rong-cheng Luo, Z. Shao

OncoTargets and Therapy

DOI

2016

High expression of microRNA-454 is associated with poor prognosis in triple-negative breast cancer

Zhi-Gang Cao, Junjing Li, L. Yao, Yan-Ni Huang, Yi-Rong Liu, Xin Hu, Chuan-Gui Song, Z. Shao

OncoTarget

DOI

2016

Transcriptome Analysis of Triple-Negative Breast Cancer Reveals an Integrated mRNA-lncRNA Signature with Predictive and Prognostic Value.

Yi-Zhou Jiang, Yi-Rong Liu, Xiao-En Xu, Xi Jin, Xin Hu, Ke-Da Yu, Z. Shao

Cancer Research

DOI

2016

The 3′UTR signature defines a highly metastatic subgroup of triple-negative breast cancer

Lei Wang, Xin Hu, Peng Wang, Z. Shao

OncoTarget

DOI

2016

Clinicopathological Characteristics and Survival Outcomes in Invasive Papillary Carcinoma of the Breast: A SEER Population-Based Study

Yi-Zi Zheng, Xin Hu, Z. Shao

Scientific Reports

DOI

2016

The phosphorylation-specific association of STMN1 with GRP78 promotes breast cancer metastasis.

X. Kuang, Hesheng Jiang, Kai Li, Yi-Zi Zheng, Yi-Rong Liu, Feng Qiao, Shan Li, Xin Hu, Z. Shao

Cancer Letters

DOI

2016

Androgen receptor expression predicts different clinical outcomes for breast cancer patients stratified by hormone receptor status

Hesheng Jiang, X. Kuang, Wei-Li Sun, Yan Xu, Yi-Zi Zheng, Yi-Rong Liu, G. Lang, Feng Qiao, Xin Hu, Z. Shao

OncoTarget

DOI

2016

Comprehensive Transcriptome Profiling Reveals Multigene Signatures in Triple-Negative Breast Cancer

Yi-Rong Liu, Yi-Zhou Jiang, Xiao-En Xu, Xin Hu, Ke-Da Yu, Z. Shao

Clinical Cancer Research

DOI

2016

Elevated expression of RNA methyltransferase BCDIN3D predicts poor prognosis in breast cancer

L. Yao, Y. Chi, Xin Hu, Shan Li, Feng Qiao, Jong Wu, Z. Shao

OncoTarget

DOI

2015

In-line phase-contrast and grating-based phase-contrast synchrotron imaging study of brain micrometastasis of breast cancer

Sheng Huang, Binquan Kou, Y. Chi, Yan Xi, Yixin Cao, Wen-Li Cui, Xin Hu, Z. Shao, Han Guo, Yanan Fu, T. Xiao, Jianqi Sun, Jun Zhao, Yu-Jie Wang, Jiong Wu

Scientific Reports

DOI

2015

Abstract P6-08-27: Glucose-regulated protein 78 and C/-EBP homologous protein predict disease-free survival and responsiveness to chemotherapy in breast cancer

Yi-Zi Zheng, Zhi-Gang Cao, Xin Hu, Z. Shao

DOI

2015

Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer.

Fu-Gui Ye, Chuan-Gui Song, Zhi-Gang Cao, Chen Xia, Dan-Na Chen, Li Chen, Shan Li, Feng Qiao, Hong Ling, L. Yao, Xin Hu, Z. Shao

Cancer Research

DOI

2015

Loss of COX5B inhibits proliferation and promotes senescence via mitochondrial dysfunction in breast cancer

Shuiping Gao, He-Fen Sun, Hong-lin Jiang, Liang-Dong Li, Xin Hu, Xiao-En Xu, W. Jin

OncoTarget

DOI

2015

Expression of autophagy-related proteins ATG5 and FIP200 predicts favorable disease-free survival in patients with breast cancer.

Lei Wang, L. Yao, Yi-Zi Zheng, Qing Xu, Xiu Liu, Xin Hu, Peng Wang, Z. Shao

Biochemical and Biophysical Research Communications - BBRC

DOI

2015

Down-Regulation of NDUFB9 Promotes Breast Cancer Cell Proliferation, Metastasis by Mediating Mitochondrial Metabolism

Liang-Dong Li, He-Fen Sun, Xue-Xiao Liu, Shuiping Gao, Hong-lin Jiang, Xin Hu, W. Jin

PLoS ONE

DOI

2015

Stathmin and phospho-stathmin protein signature is associated with survival outcomes of breast cancer patients

X. Kuang, Li Chen, Zhi-jie Zhang, Yi-Rong Liu, Yi-Zi Zheng, Hong Ling, Feng Qiao, Shan Li, Xin Hu, Z. Shao

OncoTarget

DOI

2015

Abstract P3-11-09: Elevated peripheral blood lymphocyte-to-monocyte ratio predicts favorable response and prognosis in locally advanced breast cancer after neoadjuvant chemotherapy

Lei Wang, X. Ni, Guo-Wei Qian, Qian-Wen Ou-Yang, Xiao-Lan Zhang, Yi-Zhou Jiang, Sheng Chen, Xin Hu, Z. Shao

DOI

2015

High Levels of Nucleolar Spindle-Associated Protein and Reduced Levels of BRCA1 Expression Predict Poor Prognosis in Triple-Negative Breast Cancer

Li Chen, Liu Yang, Feng Qiao, Xin Hu, Shan Li, L. Yao, Xueli Yang, Z. Shao

PLoS ONE

DOI

2015

Loss of TIM50 suppresses proliferation and induces apoptosis in breast cancer

Shuiping Gao, He-Fen Sun, Hong-lin Jiang, Liang-Dong Li, Xin Hu, Xiao-En Xu, W. Jin

Tumor Biology

DOI

2015

Abstract P6-08-28: Prognostic and predictive value of an integrated mRNA-lncRNA signature in triple-negative breast cancer: A comprehensive transcriptome analysis

Yi-Zhou Jiang, Yi-Rong Liu, Ke-Da Yu, Xin Hu, Xiao-En Xu, L. Yao, Z. Shao

DOI

2015

Identification of a Comprehensive Spectrum of Genetic Factors for Hereditary Breast Cancer in a Chinese Population by Next-Generation Sequencing

Xiaochen Yang, Jiong Wu, Jin-Song Lu, Guang-Yu Liu, Gen-Hong Di, Can-Ming Chen, Yi-Feng Hou, Meng-Hong Sun, Wentao Yang, Xiao-Jin Xu, Yingqi Zhao, Xin Hu, Da-Qiang Li, Zhi-Gang Cao, Xiaoyan Zhou, Xiao-Yan Huang, Zhe-Bin Liu, Huan Chen, Yan-zi Gu, Y. Chi, Xiangang Yan, Q. Han, Zhenzhou Shen, Z. Shao, Zhen Hu

PLoS ONE

DOI

2014

An Elevated Peripheral Blood Lymphocyte-to-Monocyte Ratio Predicts Favorable Response and Prognosis in Locally Advanced Breast Cancer following Neoadjuvant Chemotherapy

X. Ni, Xiao-Lan Zhang, Qian-Wen Ou-Yang, Guo-Wei Qian, Lei Wang, Sheng Chen, Yi-Zhou Jiang, Wen-Jia Zuo, Jiong Wu, Xin Hu, Z. Shao

PLoS ONE

DOI

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