姜宴｜复旦大学｜学者主页

2026

Development and Validation of a Rapid LC‐MS/MS Method for Quantification of 20 Bile Acids in Serum and Application to Murine Hepatotoxicity Models

Nianchang Zheng, Yaqin Niu, Juanna Wei, Lingjie Mo, Junyi Lin, Jingjing Cui, Liliang Li, Yan Jiang

Biomedical Chromatography

2025

AdipoRon ameliorates chronic ethanol induced cardiac necroptosis by reducing ceramide mediated mtROS

Yile Qian, Yanyu Qi, Junyi Lin, Tianyi Zhang, Lingjie Mo, Qiupeng Xue, Nianchang Zheng, Yaqin Niu, Xiaoru Dong, Yan Shi, Yan Jiang

Free Radical Biology and Medicine

DOI

2024

Chronic ethanol exposure induces cardiac fibroblast transdifferentiation via ceramide accumulation and oxidative stress

Tianyi Zhang, Yile Qian, Lingjie Mo, Xiaoru Dong, Qiupeng Xue, Nianchang Zheng, Yanyu Qi, Yan Jiang

Toxicology Mechanisms and Methods

DOI

2022

Inhibition of Ceramide Synthesis Attenuates Chronic Ethanol Induced Cardiotoxicity by Restoring Lysosomal Function and Reducing Necroptosis

Qiupeng Xue, Tianyi Zhang, Rongzhe Zhu, Yile Qian, Xiaoru Dong, Lingjie Mo, Yan Jiang

Alcohol and Alcoholism

DOI

2022

Diagnostic Value of PICP and PIIINP in Myocardial Fibrosis: A Systematic Review and Meta‐analysis

Tianyi Zhang, Qiupeng Xue, Rongzhe Zhu, Yan Jiang

Clinical Cardiology

DOI

2022

Comprehensive analysis of transcriptomics and metabolomics to understand chronic ethanol induced murine cardiotoxicity

Qiupeng Xue, Xiaochen Liu, Rongzhe Zhu, Tianyi Zhang, Xiaoru Dong, Yan Jiang

Molecular and Cellular Biochemistry

DOI

2022

Ethanol potentiates mirtazapine-induced cardiotoxicity by inducing dysfunctional autophagy via HMGB1-dependent Akt/mTOR signaling pathway

Rongzhe Zhu, Xiaochen Liu, Qiupeng Xue, Xiaoru Dong, Tianyi Zhang, Yan Jiang

Toxicology Letters

DOI

2020

[Review] Epigenetic mechanism of SETDB1 in brain: implications for neuropsychiatric disorders

Yueyan Zhu, Daijing Sun, Mira Jakovcevski, Yan Jiang

Translational Psychiatry，Vol. 10, No. 10

DOI

2020

CB1R Promotes Chronic Alcohol-Induced Neuronal Necroptosis in Mice Prefrontal Cortex

Lin Ye, Shuhao Li, Xiaochen Liu, Dingang Zhang, Liliang Li, Yan Jiang

Alcohol and Alcoholism

DOI

2020

Abnormally High Blood Acetaldehyde Concentrations Suggest Potential Postmortem Ethanol Generation

Xiaomin Chen, Xiaoru Dong, Rongzhe Zhu, Qiupeng Xue, Dingang Zhang, Xiaochen Liu, Lixing Zheng, Yan Jiang

Journal of Analytical Toxicology

DOI

2020

Pharmacological activation of CB2 receptor protects against ethanol-induced myocardial injury related to RIP1/RIP3/MLKL-mediated necroptosis

Xiaochen Liu, Dingang Zhang, Xiaoru Dong, Rongzhe Zhu, Yonghong Ye, Liliang Li, Yan Jiang

Molecular and Cellular Biochemistry

DOI

2020

Simultaneous Quantification of 38 Psychotropic Drugs and Relevant Metabolites in Blood using LC–MS-MS

Rongzhe Zhu, Xiaoru Dong, Dingang Zhang, Xiaochen Liu, Yong‐Hong Ye, Yan Jiang

Journal of Analytical Toxicology

DOI

2020

Proteomic Analysis of Brain Regions Reveals Brain Regional Differences and the Involvement of Multiple Keratins in Chronic Alcohol Neurotoxicity

Dingang Zhang, Xiaoru Dong, Xiaochen Liu, Lin Ye, Shuhao Li, Rongzhe Zhu, Yonghong Ye, Yan Jiang

Alcohol and Alcoholism

DOI

2019

Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors

Xiaoqing Li, Peng Zhao, Yiling Zhou, Jing Wang, Xinyi Lin, Xiaoru Dong, Xiaochen Liu, Jieqing Jiang, Yan Jiang, Liliang Li

Toxicology Letters

DOI

2019

Opposite effects of cannabinoid CB1 and CB2 receptors on antipsychotic clozapine‐induced cardiotoxicity

Liliang Li, Xiaoru Dong, Chunyan Tu, Xiaoqing Li, Peng Zhao, Yiling Zhou, Dingang Zhang, Jieqing Jiang, ALLEN P. BURKE, Ziqin Zhao, Jin Li, Yan Jiang

British Journal of Pharmacology

DOI

2018

24例长期服用精神类药物致猝死的法医学分析

叶星，史程，沈忆文，赵子琴，姜宴，李立亮

《法医学杂志》

2018

Surrogate analyte‐based quantification of main endocannabinoids in whole blood using liquid chromatography–tandem mass spectrometry

Xiaoru Dong, Liliang Li, Yong‐Hong Ye, Dingang Zhang, Lixing Zheng, Yan Jiang, Min Shen

Biomedical Chromatography

DOI

2018

Forensic Analysis of 24 Cases of Long-term Antipsychotics Use-Induced Sudden Unexpected Deaths.

X Ye, C Shi, Yiwen Shen, Ziqin Zhao, Yan Jiang, L L Li

PubMed

DOI

2017

2013—2016年134例精神疾病患者死亡案例的回顾性分析

史程，李立亮，叶永红，李凯，孙大明，姜宴

《复旦学报(医学版)》

2017

Overlooked fatal infectious diseases after long-term antipsychotic use in patients with psychiatric illness

Liliang Li, Xing Ye, Ziqin Zhao, Pan Gao, Yan Jiang

Schizophrenia Research

DOI

2017

Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects

D. Ibi, M. de la Fuente Revenga, Nebojsa Kezunovic, C. Muguruza, J. Saunders, Supriya A. Gaitonde, J. Moreno, Maryum K. Ijaz, V. Santosh, A. Kozlenkov, Terrell Holloway, Jeremy Seto, A. García-Bea, Mitsumasa Kurita, Grace E. Mosley, Yan Jiang, Daniel J. Christoffel, L. Callado, S. Russo, S. Dracheva, J. López-Giménez, Yongchao Ge, C. Escalante, J. Meana, S. Akbarian, George W. Huntley, J. González-Maeso

Nature Neuroscience

DOI

2016

大麻类物质体内代谢毒理及检测研究进展

董晓茹，姜宴，叶永红，郑力行

《药物分析杂志》

2016

Simultaneous determination of major phytocannabinoids, their main metabolites, and common synthetic cannabinoids in urine samples by LCMS/MS

Xiaoru Dong, Liliang Li, Yong‐Hong Ye, Lixing Zheng, Yan Jiang

Journal of Chromatography B

DOI

2015

法医毒物分析教学探索:感冒药中阿片类检测实验

吴争明，叶永红，林泽彬，姜宴，饶渝兰

《实验室研究与探索》

2015

Effects of triglycerides levels in human whole blood on the extraction of 19 commonly used drugs using liquid–liquid extraction and gas chromatography–mass spectrometry

Zhibin Huang, Tianfang Yu, Lin Guo, Zebin Lin, Ziqin Zhao, Yiwen Shen, Yan Jiang, Yonghong Ye, Yulan Rao

Toxicology Reports

DOI

2014

Simple and rapid analysis of four amphetamines in human whole blood and urine using liquid–liquid extraction without evaporation/derivatization and gas chromatography–mass spectrometry

Lin Guo, Zebin Lin, Zhibin Huang, Hao Liang, Yan Jiang, Yonghong Ye, Zongping Wu, Runsheng Zhang, Yurong Zhang, Yulan Rao

Forensic Toxicology

DOI

2013

多种药毒物同时检测的研究进展

李立亮，赵子琴，郑力行，姜宴

《中国法医学杂志》

2008

Chronic, but Not Acute Morphine Treatment, Up-regulates α-Ca2+/calmodulin Dependent Protein Kinase II Gene Expression in Rat Brain

Yuejun Chen, Yan Jiang, Wen Yue, Yuqing Zhou, Lin Lü, Lan Ma

Neurochemical Research

DOI

2006

生物检材中苯丙胺类兴奋剂和氯胺酮的LC-MS/MS分析

向平，卓先义，沈保华，马栋，姜宴，沈敏

《中国法医学杂志》

2006

生物检材中吗啡类生物碱的LC-MS/MS分析

向平，沈敏，沈保华，马栋，卜俊，姜宴，卓先义

《法医学杂志》

2003

Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations

Yan Jiang, Weilin Yang, Yuqing Zhou, Lan Ma

Neuroscience Letters

DOI

2002

甲基苯丙胺及其代谢产物在急性中毒豚鼠体内的分布

姜宴，沈敏，赵子琴，陈龙，叶永红，向平，沈保华

《中国法医学杂志》

2002

生物检材中甲基苯丙胺及苯丙胺的分析研究进展

姜宴，沈敏，赵子琴

《法医学杂志》

2001

甲基苯丙胺在豚鼠毛发中分布及转化的初步研究

姜宴，沈敏，赵子琴，叶永红，向平，沈保华

《法医学杂志》

2001

体内咪达唑仑代谢研究

沈保华，沈敏，卓先义，赵子琴，姜宴，吴何坚，刘伟，向平，卜俊，黄仲杰，叶永红

《中国司法鉴定》

2001

[Study of distribution and metabolism of methamphetamine in hair of guinea pig].

Yan Jiang, Min Shen, Zhao Zq, Ye Yh, Ping Xiang, Shen Bh

PubMed

2000

毛发中甲基苯丙胺及代谢产物苯丙胺的分析研究

姜宴，沈敏，赵子琴，沈保华，卜俊，叶永红

《法医学杂志》

2000

毛发中违禁苯丙胺类的代谢研究

沈敏，姜宴，向平，卜俊，沈保华

《质谱学报》

精选作品

期刊论文

Development and Validation of a Rapid LC‐MS/MS Method for Quantification of 20 Bile Acids in Serum and Application to Murine Hepatotoxicity Models

AdipoRon ameliorates chronic ethanol induced cardiac necroptosis by reducing ceramide mediated mtROS

Chronic ethanol exposure induces cardiac fibroblast transdifferentiation via ceramide accumulation and oxidative stress

Inhibition of Ceramide Synthesis Attenuates Chronic Ethanol Induced Cardiotoxicity by Restoring Lysosomal Function and Reducing Necroptosis

Diagnostic Value of PICP and PIIINP in Myocardial Fibrosis: A Systematic Review and Meta‐analysis

Comprehensive analysis of transcriptomics and metabolomics to understand chronic ethanol induced murine cardiotoxicity

Ethanol potentiates mirtazapine-induced cardiotoxicity by inducing dysfunctional autophagy via HMGB1-dependent Akt/mTOR signaling pathway

[Review] Epigenetic mechanism of SETDB1 in brain: implications for neuropsychiatric disorders

CB1R Promotes Chronic Alcohol-Induced Neuronal Necroptosis in Mice Prefrontal Cortex

Abnormally High Blood Acetaldehyde Concentrations Suggest Potential Postmortem Ethanol Generation

Pharmacological activation of CB2 receptor protects against ethanol-induced myocardial injury related to RIP1/RIP3/MLKL-mediated necroptosis

Simultaneous Quantification of 38 Psychotropic Drugs and Relevant Metabolites in Blood using LC–MS-MS

Proteomic Analysis of Brain Regions Reveals Brain Regional Differences and the Involvement of Multiple Keratins in Chronic Alcohol Neurotoxicity

Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors

Opposite effects of cannabinoid CB1 and CB2 receptors on antipsychotic clozapine‐induced cardiotoxicity

24例长期服用精神类药物致猝死的法医学分析

Surrogate analyte‐based quantification of main endocannabinoids in whole blood using liquid chromatography–tandem mass spectrometry

Forensic Analysis of 24 Cases of Long-term Antipsychotics Use-Induced Sudden Unexpected Deaths.

2013—2016年134例精神疾病患者死亡案例的回顾性分析

Overlooked fatal infectious diseases after long-term antipsychotic use in patients with psychiatric illness

Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects

大麻类物质体内代谢毒理及检测研究进展

Simultaneous determination of major phytocannabinoids, their main metabolites, and common synthetic cannabinoids in urine samples by LCMS/MS

法医毒物分析教学探索:感冒药中阿片类检测实验

Effects of triglycerides levels in human whole blood on the extraction of 19 commonly used drugs using liquid–liquid extraction and gas chromatography–mass spectrometry

Simple and rapid analysis of four amphetamines in human whole blood and urine using liquid–liquid extraction without evaporation/derivatization and gas chromatography–mass spectrometry

多种药毒物同时检测的研究进展

Chronic, but Not Acute Morphine Treatment, Up-regulates α-Ca2+/calmodulin Dependent Protein Kinase II Gene Expression in Rat Brain

生物检材中苯丙胺类兴奋剂和氯胺酮的LC-MS/MS分析

生物检材中吗啡类生物碱的LC-MS/MS分析

Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations

甲基苯丙胺及其代谢产物在急性中毒豚鼠体内的分布

生物检材中甲基苯丙胺及苯丙胺的分析研究进展

甲基苯丙胺在豚鼠毛发中分布及转化的初步研究

体内咪达唑仑代谢研究

[Study of distribution and metabolism of methamphetamine in hair of guinea pig].

毛发中甲基苯丙胺及代谢产物苯丙胺的分析研究

毛发中违禁苯丙胺类的代谢研究

研究方向