戚丽霜｜哈尔滨医科大学｜学者主页

2026

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Li-Ying Wang, Gang Xu, Rou Li, D. Jia, Yan Yu

Advancement of science

DOI

2025

Integrating multi-omics to unveil PSMD12 as a critical gene in promoting brain metastases of lung adenocarcinoma

Xin Li, Ju-Xuan Zhang, Meng Zhang, Wenbin Jiang, D. Jia, Ruxiong Wang, Hao Li, Zhihui Wang, Yixin Liu, Lefan Tang, Jiaxing Deng, Wenyuan Zhao, Yan Yu, Shilong Liu, Lishuang Qi

Journal of Translational Medicine

DOI

2025

RBM15 recruits myeloid-derived suppressor cells via the m6A-IGF2BP3/CBR3-AS1/miR-409-3p/CXCL1 axis, facilitating radioresistance in non-small-cell lung cancer

Song-Liu Hu, Ning Zhan, Jian Li, Liqun Wang, Yiyan Liu, Ke Jin, Yi-Xuan Wang, Ju-Xuan Zhang, Yiyang Chen, Yang Bai, Yi-Chong Wang, Lishuang Qi, Shilong Liu

Journal of Translational Medicine

DOI

2024

Identification of a rank-based radiomic signature with individualized prognostic value for lung adenocarcinoma in a multi-cohort study.

Yixin Liu, Zhihui Wang, Liping Yang, Meng Zhang, Mengyue Li, Ju-Xuan Zhang, Lefan Tang, Zhi-Yun Jiang, Xin Li, Jiaxing Deng, Qingwei Meng, Shilong Liu, Ke-Zheng Wang, Lishuang Qi

European Journal of Radiology

DOI

2024

Draw on advantages and avoid disadvantages: CT-derived individualized radiomic signature for predicting chemo-radiotherapy sensitivity in unresectable advanced non-small cell lung cancer

Liping Yang, Mengyue Li, Yixin Liu, Zhi-Yun Jiang, Shichuan Xu, Hongchao Ding, Xing Gao, Shilong Liu, Lishuang Qi, Ke-Zheng Wang

Journal of Cancer Research and Clinical Oncology

DOI

2024

RHBDF1 modulates cisplatin sensitivity of small cell lung cancer through YAP1/Smad2 signaling pathway

Lei Wang, Lishuang Qi, Xiaoyi Huang, Xiao Feng, Junqing Gan, Juxuan Zhang, Yuhui Xi, Shuai Zhang, Qingwei Meng

Heliyon

DOI

2023

Sec61γ is a vital protein in the endoplasmic reticulum membrane promoting tumor metastasis and invasion in lung adenocarcinoma

Shanqi Xu, Xin Li, Jianxiong Geng, Yingyue Cao, Yan Yu, Lishuang Qi

British Journal of Cancer

DOI

2022

Identification of mutational signature for lung adenocarcinoma prognosis and immunotherapy prediction

Sainan Zhang, Mengyue Li, Yilong Tan, Juxuan Zhang, Yixin Liu, Wenbin Jiang, Xin Li, Haitao Qi, Lefan Tang, Ran Ji, Wenyuan Zhao, Yunyan Gu, Lishuang Qi

Journal of Molecular Medicine

DOI

2022

A genetic map of the chromatin regulators to drug response in cancer cells

Bo Chen, Pengfei Li, Mingyue Liu, Kaidong Liu, Min Zou, Yiding Geng, Shuping Zhuang, Huanhuan Xu, Linzhu Wang, Tingting Chen, Yawei Li, Zhangxiang Zhao, Lishuang Qi, Yunyan Gu

Journal of Translational Medicine

DOI

2022

Hierarchical identification of a transcriptional panel for the histological diagnosis of lung neuroendocrine tumors

Juxuan Zhang, Jiaxing Deng, Xiao Feng, Yilong Tan, Xin Li, Yixin Liu, Mengyue Li, Haitao Qi, Lefan Tang, Qingwei Meng, Haidan Yan, Lishuang Qi

Frontiers in Genetics

DOI

2022

Predicting Chemo-Radiotherapy Sensitivity With Concordant Survival Benefit in Non-Small Cell Lung Cancer via Computed Tomography Derived Radiomic Features

Yixin Liu, Haitao Qi, Chunni Wang, Jiaxing Deng, Yilong Tan, Lin Lin, Zhirou Cui, Jin Li, Lishuang Qi

Frontiers in Oncology

DOI

2021

Identifying 18F-FDG PET-metabolic radiomic signature for lung adenocarcinoma prognosis via the leveraging of prognostic transcriptomic module

Jin Li, Yixin Liu, Wenlei Dong, Yang Zhou, WU Jing-quan, Kuan Luan, Lishuang Qi

Quantitative Imaging in Medicine and Surgery

DOI

2021

RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma

Yingyue Cao, Jianxiong Geng, Xin Wang, Qingwei Meng, Shanqi Xu, Yaoguo Lang, Yongxu Zhou, Lishuang Qi, Zijie Wang, Zixin Wei, Yan Yu, Jin Shi, Bo Pan

International Journal of Biological Sciences

DOI

2021

Revealing biomarkers associated with PARP inhibitors based on genetic interactions in cancer genome

Qi Dong, Mingyue Liu, Bo Chen, Zhangxiang Zhao, Tingting Chen, Chengyu Wang, Shuping Zhuang, Yawei Li, Yuquan Wang, Liqiang Ai, Yaoyao Liu, Haihai Liang, Lishuang Qi, Yunyan Gu

Computational and Structural Biotechnology Journal

DOI

2021

The value of AGR2 and KRT5 as an immunomarker combination in distinguishing lung squamous cell carcinoma from adenocarcinoma.

Bo Pan, Zixin Wei, Juxuan Zhang, Xin Li, Qingwei Meng, Yingyue Cao, Lishuang Qi, Yan Yu

PubMed

2020

An individualized transcriptional signature to predict the epithelial-mesenchymal transition based on relative expression ordering

Tingting Chen, Zhangxiang Zhao, Bo Chen, Yuquan Wang, Fan Yang, Chengyu Wang, Qi Dong, Yaoyao Liu, Haihai Liang, Wenyuan Zhao, Lishuang Qi, Yan Xu, Yunyan Gu

Aging

DOI

2020

Reference genome and annotation updates lead to contradictory prognostic predictions in gene expression signatures: a case study of resected stage I lung adenocarcinoma

Zheyang Zhang, Sainan Zhang, Xin Li, Zhangxiang Zhao, Changjing Chen, Juxuan Zhang, Mengyue Li, Zixin Wei, Wenbin Jiang, Bo Pan, Ying Li, Yixin Liu, Yingyue Cao, Wenyuan Zhao, Yunyan Gu, Yan Yu, Qingwei Meng, Lishuang Qi

Briefings in Bioinformatics

DOI

2020

Identification of a small mutation panel of coding sequences to predict the efficacy of immunotherapy for lung adenocarcinoma

Ying Li, Wenbin Jiang, Tianhao Li, Mengyue Li, Xin Li, Zheyang Zhang, Sainan Zhang, Yixin Liu, Wenyuan Zhao, Yunyan Gu, Lishuang Qi, Lu Ao, Zheng Guo

Journal of Translational Medicine

DOI

2019

An absolute human stemness index associated with oncogenic dedifferentiation

Hailong Zheng, Kai Song, Yelin Fu, Tianyi You, Jing Yang, Wenbing Guo, Kai Wang, Liangliang Jin, Yunyan Gu, Lishuang Qi, Wenyuan Zhao

Briefings in Bioinformatics

DOI

2019

A qualitative transcriptional signature for the histological reclassification of lung squamous cell carcinomas and adenocarcinomas

Xin Li, Gengen Shi, Qing‐Song Chu, Wenbin Jiang, Yixin Liu, Sainan Zhang, Zheyang Zhang, Zixin Wei, Fei He, Zheng Guo, Lishuang Qi

BMC Genomics

DOI

2019

Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells

Yue Han, Chengyu Wang, Qi Dong, Tingting Chen, Fan Yang, Yaoyao Liu, Bo Chen, Zhangxiang Zhao, Lishuang Qi, Wenyuan Zhao, Haihai Liang, Zheng Guo, Yunyan Gu

Molecular Therapy — Nucleic Acids

DOI

2019

Identifying primary site of lung-limited Cancer of unknown primary based on relative gene expression orderings

Mengyao Li, Hongdong Li, Guini Hong, Zhongjie Tang, Guanghao Liu, Xiaofang Lin, Mingzhang Lin, Lishuang Qi, Zheng Guo

BMC Cancer

DOI

2017

A rank-based algorithm of differential expression analysis for small cell line data with statistical control

Xiangyü Li, Hao Cai, Xianlong Wang, Lu Ao, You Guo, Jun He, Yunyan Gu, Lishuang Qi, Qingzhou Guan, Xu Lin, Zheng Guo

Briefings in Bioinformatics

DOI

2017

An individualized gene expression signature for prediction of lung adenocarcinoma metastases

Lishuang Qi, Tianhao Li, Gengen Shi, Jiasheng Wang, Xin Li, Sainan Zhang, Libin Chen, Yuan Qin, Yunyan Gu, Wenyuan Zhao, Zheng Guo

Molecular Oncology

DOI

2017

Identification of driver copy number alterations in diverse cancer types and application in drug repositioning

Wenbin Zhou, Zhangxiang Zhao, Ruiping Wang, Yue Han, Chengyu Wang, Fan Yang, Ya Han, Haihai Liang, Lishuang Qi, Chenguang Wang, Zheng Guo, Yunyan Gu

Molecular Oncology

DOI

2017

Differential expression analysis at the individual level reveals a lncRNA prognostic signature for lung adenocarcinoma

Fuduan Peng, Ruiping Wang, Yuanyuan Zhang, Zhangxiang Zhao, Wenbin Zhou, Zhiqiang Chang, Haihai Liang, Wenyuan Zhao, Lishuang Qi, Zheng Guo, Yunyan Gu

Molecular Cancer

DOI

2016

A landscape of synthetic viable interactions in cancer

Yunyan Gu, Ruiping Wang, Yue Han, Wenbin Zhou, Zhangxiang Zhao, Tingting Chen, Yuanyuan Zhang, Fuduan Peng, Haihai Liang, Lishuang Qi, Wenyuan Zhao, Da Yang, Zheng Guo

Briefings in Bioinformatics

DOI

2016

An individualised signature for predicting response with concordant survival benefit for lung adenocarcinoma patients receiving platinum-based chemotherapy

Lishuang Qi, Yang Li, Yuan Qin, Gengen Shi, Tianhao Li, Jiasheng Wang, Libin Chen, Yunyan Gu, Wenyuan Zhao, Zheng Guo

British Journal of Cancer

DOI

2015

The influence of cancer tissue sampling on the identification of cancer characteristics

Hui Xu, Xin Guo, Qiang Sun, Mengmeng Zhang, Lishuang Qi, Yang Li, Libin Chen, Yunyan Gu, Zheng Guo, Wenyuan Zhao

Scientific Reports

DOI

2015

Critical limitations of prognostic signatures based on risk scores summarized from gene expression levels: a case study for resected stage I non-small-cell lung cancer

Lishuang Qi, Libin Chen, Yang Li, Yuan Qin, Rufei Pan, Wenyuan Zhao, Yunyan Gu, Hongwei Wang, Ruiping Wang, Xiangqi Chen, Zheng Guo

Briefings in Bioinformatics

DOI

2015

Individualized identification of disease-associated pathways with disrupted coordination of gene expression

Hongwei Wang, Hao Cai, Lu Ao, Haidan Yan, Wenyuan Zhao, Lishuang Qi, Yunyan Gu, Zheng Guo

Briefings in Bioinformatics

DOI

2014

Individual-level analysis of differential expression of genes and pathways for personalized medicine

Hongwei Wang, Qiang Sun, Wenyuan Zhao, Lishuang Qi, Yunyan Gu, Pengfei Li, Mengmeng Zhang, Yang Li, Shu‐Lin Liu, Zheng Guo

Bioinformatics

DOI

2014

Deconvolution of the Gene Expression Profiles of Valuable Banked Blood Specimens for Studying the Prognostic Values of Altered Peripheral Immune Cell Proportions in Cancer Patients

Lishuang Qi, Bailiang Li, Yu Dong, Hui Xu, Libin Chen, Hongwei Wang, Pengfei Li, Wenyuan Zhao, Yunyan Gu, Chenguang Wang, Zheng Guo

PLoS ONE

DOI

2013

Pitfalls in Experimental Designs for Characterizing the Transcriptional, Methylational and Copy Number Changes of Oncogenes and Tumor Suppressor Genes

Yuannv Zhang, Jiguang Xia, Yujing Zhang, Yao Qin, Da Yang, Lishuang Qi, Wenyuan Zhao, Chenguang Wang, Zheng Guo

PLoS ONE

DOI

精选作品

期刊论文

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Integrating multi-omics to unveil PSMD12 as a critical gene in promoting brain metastases of lung adenocarcinoma

RBM15 recruits myeloid-derived suppressor cells via the m6A-IGF2BP3/CBR3-AS1/miR-409-3p/CXCL1 axis, facilitating radioresistance in non-small-cell lung cancer

Identification of a rank-based radiomic signature with individualized prognostic value for lung adenocarcinoma in a multi-cohort study.

Draw on advantages and avoid disadvantages: CT-derived individualized radiomic signature for predicting chemo-radiotherapy sensitivity in unresectable advanced non-small cell lung cancer

RHBDF1 modulates cisplatin sensitivity of small cell lung cancer through YAP1/Smad2 signaling pathway

Sec61γ is a vital protein in the endoplasmic reticulum membrane promoting tumor metastasis and invasion in lung adenocarcinoma

Identification of mutational signature for lung adenocarcinoma prognosis and immunotherapy prediction

A genetic map of the chromatin regulators to drug response in cancer cells

Hierarchical identification of a transcriptional panel for the histological diagnosis of lung neuroendocrine tumors

Predicting Chemo-Radiotherapy Sensitivity With Concordant Survival Benefit in Non-Small Cell Lung Cancer via Computed Tomography Derived Radiomic Features

Identifying 18F-FDG PET-metabolic radiomic signature for lung adenocarcinoma prognosis via the leveraging of prognostic transcriptomic module

RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma

Revealing biomarkers associated with PARP inhibitors based on genetic interactions in cancer genome

The value of AGR2 and KRT5 as an immunomarker combination in distinguishing lung squamous cell carcinoma from adenocarcinoma.

An individualized transcriptional signature to predict the epithelial-mesenchymal transition based on relative expression ordering

Reference genome and annotation updates lead to contradictory prognostic predictions in gene expression signatures: a case study of resected stage I lung adenocarcinoma

Identification of a small mutation panel of coding sequences to predict the efficacy of immunotherapy for lung adenocarcinoma

An absolute human stemness index associated with oncogenic dedifferentiation

A qualitative transcriptional signature for the histological reclassification of lung squamous cell carcinomas and adenocarcinomas

Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells

Identifying primary site of lung-limited Cancer of unknown primary based on relative gene expression orderings

A rank-based algorithm of differential expression analysis for small cell line data with statistical control

An individualized gene expression signature for prediction of lung adenocarcinoma metastases

Identification of driver copy number alterations in diverse cancer types and application in drug repositioning

Differential expression analysis at the individual level reveals a lncRNA prognostic signature for lung adenocarcinoma

A landscape of synthetic viable interactions in cancer

An individualised signature for predicting response with concordant survival benefit for lung adenocarcinoma patients receiving platinum-based chemotherapy

The influence of cancer tissue sampling on the identification of cancer characteristics

Critical limitations of prognostic signatures based on risk scores summarized from gene expression levels: a case study for resected stage I non-small-cell lung cancer

Individualized identification of disease-associated pathways with disrupted coordination of gene expression

Individual-level analysis of differential expression of genes and pathways for personalized medicine

Deconvolution of the Gene Expression Profiles of Valuable Banked Blood Specimens for Studying the Prognostic Values of Altered Peripheral Immune Cell Proportions in Cancer Patients

Pitfalls in Experimental Designs for Characterizing the Transcriptional, Methylational and Copy Number Changes of Oncogenes and Tumor Suppressor Genes

会议论文

基于基因表达秩序关系识别非小细胞肺癌组织学亚型的鉴别标志

Ⅰ-Ⅱ期肺腺癌癌微转移预测及铂类耐药预测双联标志

预印本

RBM10 Interacts with CTBNNBIP1 and Represses Lung Adenocarcinoma Progression Through the Wnt/β- catenin Pathway

研究方向