张醉｜复旦大学｜学者主页

2026

脂质纳米药物递送系统

张醉，丁天皓，江宽，吴尔灿，庄卓萍，占昌友

《中国新药杂志》

2026

Hydroxyl-Terminated Polyethylene Glycol Evades Human Pre-existing Anti-polyethylene Glycol Antibodies.

Tian-Hao Ding, Jia-Ru Fu, Min Yang, Zui Zhang, Yinyu Ma, Ercan Wu, Zhiwei Guo, Shiqi Lin, Songli Wang, Xiaohua Liu, Weiping Wang, Bin Wang, Guanghui Li, Chang-You Zhan

ACS Nano

DOI

2026

Engineered protein corona by Bispecific Antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect

Xiaoli Wei, Tianhao Ding, Meili Xi, Kristofer J. Thurecht, Christopher B. Howard, Ji-Wei Cui, Changyou Zhan, Zui Zhang

Nano Today

DOI

2025

Activated platelet membrane vesicles for broad-spectrum bacterial pulmonary infections management.

Anqi Wei, Tianhao Ding, Guanghui Li, Feng Pan, Kaisong Tian, Ziwei Sun, Mengyuan Liu, Yinyu Ma, Zhiwei Guo, Yifei Yu, Chang-You Zhan, Zui Zhang, Ye Zhu, Xiaoli Wei

Journal of Controlled Release

DOI

2025

Pulmonary mRNA-LNP vaccines for rapid and durable protection against bacterial infection

Anqi Wei, Yu Miao, Zhou Yuan, Guanghui Li, D. Lei, Yinyu Ma, Zhiwei Guo, Yuansong Sun, Tianhao Ding, Kaisong Tian, Qin He, Zui Zhang, Lianfeng Fan, Chang-You Zhan, Xiaoli Wei

bioRxiv

DOI

2024

Brain-targeted drug delivery by in vivo functionalized liposome with stable D-peptide ligand.

Yang Yang, Yuxiu Chu, Cheng Li, Lianfeng Fan, Huiping Lu, Changyou Zhan, Zui Zhang

Journal of Controlled Release

DOI

2024

Exemplifying interspecies variation of liposome in vivo fate by the effects of anti-PEG antibodies

Ercan Wu, Juan Guan, Yifei Yu, Shiqi Lin, Tian-Hao Ding, Yuxiu Chu, Feng Pan, Mengyuan Liu, Yang Yang, Zui Zhang, Jian Zhang, Chang-You Zhan, Jun Qian

Acta Pharmaceutica Sinica B

DOI

2024

Hydroxy polyethylene glycol: a solution to evade human pre-existing anti-PEG antibodies for efficient delivery

Tian-Hao Ding, Jia-Ru Fu, Min Yang, Zui Zhang, Yinyu Ma, Ercan Wu, Zhiwei Guo, Shiqi Lin, Songli Wang, Xiaohuang Liu, Bin Wang, Guanghui Li, Chang-You Zhan

bioRxiv

DOI

2023

Effects of PEG antibodies on in vivo performance of LNP-mRNA vaccines.

Min Yang, Zeng-Yu Zhang, Pengpeng Jin, Kuan Jiang, Yifei Xu, Feng Pan, Kaisong Tian, Zhou Yuan, Xiaohua Eric Liu, Jia-Ru Fu, Bin Wang, Huafang Yan, Chang-You Zhan, Zui Zhang

International journal of pharmaceutics

DOI

2021

Facile Separation of PEGylated Liposomes Enabled by Anti-PEG scFv.

Wenjing Tang, Zui Zhang, Cheng Li, Yuxiu Chu, Jun Qian, T. Ying, Wei-Yue Lu, C. Zhan

Nano letters (Print)

DOI

2021

Deciphering Protein Corona by scFv-Based Affinity Chromatography.

Yuxiu Chu, Wenjing Tang, Zui Zhang, Cheng Li, Jun Qian, Xiao-Li Wei, T. Ying, Weiyue Lu, C. Zhan

Nano letters (Print)

DOI

2020

Unraveling GLUT‐mediated transcytosis pathway of glycosylated nanodisks

Huan Wang, Zui Zhang, J. Guan, Wei-Yue Lu, C. Zhan

Asian Journal of Pharmaceutical Sciences

DOI

2020

Anti-PEG scFv corona ameliorates accelerated blood clearance phenomenon of PEGylated nanomedicines.

Zui Zhang, Yuxiu Chu, Cheng Li, Wenjing Tang, Jun Qian, Xiao-Li Wei, Weiyue Lu, T. Ying, C. Zhan

Journal of Controlled Release

DOI

2019

Receptor-mediated transportation through BBB

Zui Zhang, C. Zhan

Brain Targeted Drug Delivery System

DOI

2019

Brain-targeted drug delivery by manipulating protein corona functions

Zui Zhang, J. Guan, Zhu-Xuan Jiang, Yang Yang, Ji-Can Liu, W. Hua, Ying Mao, Cheng Li, Weiyue Lu, Jun Qian, C. Zhan

Nature Communications

DOI

2019

Contributors

Ru-Jing Chen, S. Dhanda, Jiajun Fan, Huile Gao, Xiaoling Gao, Xiaojiao Ge, Xiao Gu, Qian Guo, Smriti Gupta, Liang Han, X. Hao, Kai-Li Hu, Yi-Lan Huang, Rong-Qin Huang, Meng Huang, Yongzhuo Huang, Kai Jin, Xiufeng Ju, D. Ju, Naveed Ullah Khan, Wahid Khan, G. Kulkarni, Guang-Zhe Li, Cheng-Yi Li, Cong Li, Yu-Bin Li, Qingfeng Liu, Er-Gang Liu, Kanishk Luhach, Tongtong Miao, Xiao-Peng Mo, Z. Pang, Min Qian, Raju Saka, R. Sandhir, Priyadarshini Sathe, K. Shao, B. Sharma, Xiaoyu Shen, C. S. Umeshappa, Shanshan Wang, Hualin Wang, C. Zhan, Zui Zhang, Qizhi Zhang, Yuyan Zhang, Xiao Zhao, Xiaowen Zhu

Brain Targeted Drug Delivery System

DOI

2018

Enhanced immunocompatibility of ligand-targeted liposomes by attenuating natural IgM absorption

J. Guan, Qing Shen, Zui Zhang, Zhu-Xuan Jiang, Yang Yang, Meiqi Lou, Jun Qian, Weiyue Lu, C. Zhan

Nature Communications

DOI

2017

Cholera Toxin Subunit B Enabled Multifunctional Glioma‐Targeted Drug Delivery

J. Guan, Zui Zhang, Xue-Feng Hu, Yang Yang, Zhilan Chai, Xiaoqin Liu, Ji-Can Liu, Bo Gao, Weiyue Lu, Jun Qian, C. Zhan

Advanced Healthcare Materials

DOI

张醉

精选作品

期刊论文

脂质纳米药物递送系统

Hydroxyl-Terminated Polyethylene Glycol Evades Human Pre-existing Anti-polyethylene Glycol Antibodies.

Engineered protein corona by Bispecific Antibody endows liposome with enhanced tumor targeting ability and mitigated accelerated blood clearance effect

Activated platelet membrane vesicles for broad-spectrum bacterial pulmonary infections management.

Pulmonary mRNA-LNP vaccines for rapid and durable protection against bacterial infection

Brain-targeted drug delivery by in vivo functionalized liposome with stable D-peptide ligand.

Exemplifying interspecies variation of liposome in vivo fate by the effects of anti-PEG antibodies

Hydroxy polyethylene glycol: a solution to evade human pre-existing anti-PEG antibodies for efficient delivery

Effects of PEG antibodies on in vivo performance of LNP-mRNA vaccines.

Facile Separation of PEGylated Liposomes Enabled by Anti-PEG scFv.

Deciphering Protein Corona by scFv-Based Affinity Chromatography.

Unraveling GLUT‐mediated transcytosis pathway of glycosylated nanodisks

Anti-PEG scFv corona ameliorates accelerated blood clearance phenomenon of PEGylated nanomedicines.

Receptor-mediated transportation through BBB

Brain-targeted drug delivery by manipulating protein corona functions

Contributors

Enhanced immunocompatibility of ligand-targeted liposomes by attenuating natural IgM absorption

Cholera Toxin Subunit B Enabled Multifunctional Glioma‐Targeted Drug Delivery