胡家铭｜上海大学｜学者主页

2026

CRISPR/Cas13a: Compensatory Target Activation Mechanism

Bowen Jiang, Tenghua Zhang, Yao Lu, Shujun Zhou, Wenjing Xiao, Shuming Pan, Nan Shi, Yan Sheng, Jiaming Hu

Advanced Science

DOI

2026

CRISPR/Cas system for real-time water quality monitoring: Advances and challenges

Mei-Ru Liu, Zena Huang, Yan Lin, Yan-Yan Li, Weixue Xu, Yao Lu, Sicheng Cui, Tenghua Zhang, Yan Sheng, Jiaming Hu

Trends in Analytical Chemistry (TrAC)

DOI

2025

Modular Microfluidic Sensor Integrating Nucleic Acid Extraction, CRISPR/Cas13a, and Electrochemiluminescence for Multichannel RNA Detection.

Xinyuan Mao, Yao Lu, Zixi Gao, Jie Zhong, A. Xiao, Jin-Qiong Lin, Jiaming Hu, Bowen Shu, Chun-Sun Zhang

Analytical Chemistry

DOI

2025

Split proximity circuit initiated CRISPR-Cas12a system profiling exosomal surface proteins for early cancer detection.

Weixue Xu, Yan Lin, Zena Huang, Yanyan Li, Yao Lu, Mei-Ru Liu, Sicheng Cui, Tenghua Zhang, Nan Shi, Yan Sheng, Jiaming Hu

Biosensors & bioelectronics

DOI

2025

A bead-based dendritic amplification system for multiplex miRNA detection

Feiyang Qian, Rui Zhu, Yao Lu, Tenghua Zhang, Yu-Qing Zhu, Yan Sheng, Jiaming Hu

Chemical Engineering Journal

DOI

2024

The CRISPR-Cas13a Gemini System for noncontiguous target RNA activation

Hongrui Zhao, Yan Sheng, Tenghua Zhang, Shujun Zhou, Yu-Qing Zhu, Feiyang Qian, Mei-Ru Liu, Weixue Xu, Deng-Song Zhang, Jiaming Hu

Nature Communications

DOI

2024

An amplification-free CRISPR/cas13a-powered dry chemistry-based electrochemiluminescence gene sensor for ultrasensitive RNA detection

Xiao-Ya Liu, Shujun Zhou, R. Sun, Kang-Min Ye, Yao Lu, An He, Yang Yang, Jin-Qiong Lin, Jiaming Hu, Chun-Sun Zhang

Sensors and actuators. B, Chemical

DOI

2024

Correction: Polydopamine-assisted aptamer-carrying tetrahedral DNA microelectrode sensor for ultrasensitive electrochemical detection of exosomes

Bowen Jiang, Tenghua Zhang, Silan Liu, Yan Sheng, Jiaming Hu

Journal of Nanobiotechnology

DOI

2024

Polydopamine-assisted aptamer-carrying tetrahedral DNA microelectrode sensor for ultrasensitive electrochemical detection of exosomes

Bowen Jiang, Tenghua Zhang, Silan Liu, Yan Sheng, Jiaming Hu

Journal of Nanobiotechnology

DOI

2023

CRISPR-Cas12a powered multifunctional DNA nanodumbbell lock biosensor for multiple molecular detection

Yu-Qing Zhu, Xiaohe Zheng, Rui Zhu, Hongrui Zhao, Hongli Zhai, Feiyang Qian, Tenghua Zhang, Zi-Hui Xie, Silan Liu, Bowen Jiang, Yan Sheng, Jiaming Hu

Chemical Engineering Journal

DOI

2023

CRISPR-Cas12a powered hybrid nanoparticle for extracellular vesicle aggregation and in-situ microRNA detection.

Tenghua Zhang, Zi-Hui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Han-Kang Zhong, Feiyang Qian, Yu-Qing Zhu, Rui-Ting Sun, Yan Sheng, Jiaming Hu

Biosensors & bioelectronics

DOI

2023

Cas-Rainbow: Cas12a-driven single-reaction multiplex detection system

Yu-Qing Zhu, Jianming Zhou, Yuxin Liang, Yao Lu, Shujun Zhou, Feiyang Qian, Tenghua Zhang, Yan Sheng, Jiaming Hu

Chemical Engineering Journal

DOI

2023

A dual amplification-based CRISPR/Cas12a biosensor for sensitive detection of miRNA in prostate cancer.

Yu-Qing Zhu, Xiaohe Zheng, Shujun Zhou, Wenjing Xiao, Xiaorui Sun, Jianming Zhou, Feiyang Qian, Tenghua Zhang, Yan Sheng, Jiaming Hu

Analytica Chimica Acta

DOI

2022

Living Cell Nanoporation and Exosomal RNA Analysis Platform for Real-Time Assessment of Cellular Therapies.

Yan Sheng, Ze-Na Huang, Tenghua Zhang, Feiyang Qian, Yu-Qing Zhu, Zaizai Dong, Qing-yang Zhang, Qi Lei, Fanhui Kong, Yuqiong Wang, Madeline Walden, S. Wuttke, Lingqian Chang, Wei Zhu, Jiaming Hu

Journal of the American Chemical Society

DOI

2022

Analysis and Biomedical Applications of Functional Cargo in Extracellular Vesicles.

Feiyang Qian, Ze-Na Huang, Han-Kang Zhong, Qi Lei, Yirui Ai, Zi-Hui Xie, Tenghua Zhang, Bowen Jiang, Wei Zhu, Yan Sheng, Jiaming Hu, C. Brinker

ACS Nano

DOI

2021

A CRISPR/Cas13a-powered catalytic electrochemical biosensor for successive and highly sensitive RNA diagnostics.

Yan Sheng, Tenghua Zhang, Shi-Hong Zhang, M. Johnston, Xiaohe Zheng, Yuanyue Shan, Tong Liu, Ze-Na Huang, Feiyang Qian, Zi-Hui Xie, Yirui Ai, Han-Kang Zhong, Tai-Rong Kuang, C. Dincer, G. Urban, Jiaming Hu

Biosensors & bioelectronics

DOI

2020

Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction

Jinjin Shen, Xiaoming Zhou, Yuanyue Shan, Huahua Yue, Ru Huang, Jiaming Hu, D. Xing

Nature Communications

DOI

2020

Cascade CRISPR/cas enables amplification-free microRNA sensing with fM-sensitivity and single-base-specificity.

Yong-Ling Sha, Ru Huang, Mengqi Huang, Huahua Yue, Yuanyue Shan, Jiaming Hu, D. Xing

Chemical Communications

DOI

胡家铭

精选作品

期刊论文

CRISPR/Cas13a: Compensatory Target Activation Mechanism

CRISPR/Cas system for real-time water quality monitoring: Advances and challenges

Modular Microfluidic Sensor Integrating Nucleic Acid Extraction, CRISPR/Cas13a, and Electrochemiluminescence for Multichannel RNA Detection.

Split proximity circuit initiated CRISPR-Cas12a system profiling exosomal surface proteins for early cancer detection.

A bead-based dendritic amplification system for multiplex miRNA detection

The CRISPR-Cas13a Gemini System for noncontiguous target RNA activation

An amplification-free CRISPR/cas13a-powered dry chemistry-based electrochemiluminescence gene sensor for ultrasensitive RNA detection

Correction: Polydopamine-assisted aptamer-carrying tetrahedral DNA microelectrode sensor for ultrasensitive electrochemical detection of exosomes

Polydopamine-assisted aptamer-carrying tetrahedral DNA microelectrode sensor for ultrasensitive electrochemical detection of exosomes

CRISPR-Cas12a powered multifunctional DNA nanodumbbell lock biosensor for multiple molecular detection

CRISPR-Cas12a powered hybrid nanoparticle for extracellular vesicle aggregation and in-situ microRNA detection.

Cas-Rainbow: Cas12a-driven single-reaction multiplex detection system

A dual amplification-based CRISPR/Cas12a biosensor for sensitive detection of miRNA in prostate cancer.

Living Cell Nanoporation and Exosomal RNA Analysis Platform for Real-Time Assessment of Cellular Therapies.

Analysis and Biomedical Applications of Functional Cargo in Extracellular Vesicles.

A CRISPR/Cas13a-powered catalytic electrochemical biosensor for successive and highly sensitive RNA diagnostics.

Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction

Cascade CRISPR/cas enables amplification-free microRNA sensing with fM-sensitivity and single-base-specificity.

研究方向