陈璞｜武汉大学｜学者主页

2026

利用跨胚层共发育类器官芯片生物工程构建心脑共发育体模型（英文）

Xuemei Huang, Wen Zhao, Yuwen Wang, Yuxin Wang, Tao Chen, Lili Zhu, Yiran Zhang, Jibo Wang, Hanwen Cao, Yuhang Fan, Yunnan Liu, Xiaobing Jiang, Linlin Bi, Changyong Li, Pu Chen

Engineering

2026

High-throughput colorectal cancer organoid-on-a-chip for single-organoid-analysis-based personalized drug evaluation

Shuyan Xiong, Yong Zhao, Xi Cheng, Lingxiu Zeng, Yuwen Wang, Ying Zhou, Xiaoqiao Bai, Jibo Wang, Jie Hu, Yunnan Liu, Hanwen Cao, Chunyang Zhou, Changyong Li, Jing Liu, Pu Chen

Bio-Design and Manufacturing

精选作品

期刊论文

利用跨胚层共发育类器官芯片生物工程构建心脑共发育体模型（英文）

High-throughput colorectal cancer organoid-on-a-chip for single-organoid-analysis-based personalized drug evaluation

Human BBB-brain organoid on a millifluidic plate for modeling brain parenchymal pathology-induced barrier dysfunction

Spatiotemporal quantification of nanoplastic-induced oxidative stress in 3D cortical organoids by flexible electrodes

Erratum to “CX3CR1+ Monocytes/Macrophages Promote Regional Immune Injury in Mesangial Proliferative Glomerulonephritis through Crosstalk with Activated Mesangial Cells”

Clinical utility of BOLD-MRI in accurate diagnosis and prognostic evaluation of diabetic nephropathy: a prospective renal biopsy-based cohort study

Single-nephron eGFR and kidney function decline in IgA nephropathy.

Development of machine learning-driven non-invasive diagnostic models for idiopathic membranous nephropathy in Chinese patients.

An explainable machine learning model for predicting in-hospital infection in patients with systemic lupus erythematosus

Merging artificial intelligence and retinal vascular geometric parameters: A novel tool for diagnosis and prognosis prediction of diabetic nephropathy

Exertional heat stroke-related acute kidney injury: novel animal and cellular models

Bioengineering of Heart–Brain Codevelopoid Model via Trans-Germ-Layer Codevelopment Organoid Chip

High‐Throughput Formation of Pre‐Vascularized hiPSC‐Derived Hepatobiliary Organoids on a Chip via Nonparenchymal Cell Grafting

All-in-one generation and multiomic profiling of human whole brain organoid on a millifluidic plate

Compelling standardized and high-throughput micro-/millifluidic plates for biomedical research: from laboratory to market

Injectable and drug-loaded gelatin methacrylate and carboxymethylated-sulfated xanthan gum hydrogels as biomimetic mineralization constructs.

CX3CR1+ Monocytes/Macrophages Promote Regional Immune Injury in Mesangial Proliferative Glomerulonephritis through Crosstalk with Activated Mesangial Cells

Application of low-vacuum scanning electron microscopy and energy-dispersive X-ray spectrometry for detection of renal tubular crystals: a case of nephrocalcinosis in the setting of anorexia nervosa

Development and validation of a single-nephron estimated glomerular filtration rate model to predict disease progression in IgA nephropathy

Soft-lithographically defined template for arbitrarily patterned acoustic bioassembly

Depleting profibrotic macrophages using bioactivated in vivo assembly peptides ameliorates kidney fibrosis

The relationship between diabetic retinopathy and diabetic nephropathy in type 2 diabetes

External Validation of the International IgA Nephropathy Prediction Tool in Older Adult Patients

Correlation between retinal vascular geometric parameters and pathologically diagnosed type 2 diabetic nephropathy

Rational Design and Acoustic Assembly of Human Cerebral Cortex‐Like Microtissues from hiPSC‐Derived Neural Progenitors and Neurons

Ultrasound-controlled nano oxygen carriers enhancing cell viability in 3D GelMA hydrogel for the treatment of myocardial infarction

Bioengineering of a human physiologically relevant microfluidic blood-cerebrospinal fluid barrier model.

Serum levels of sonic hedgehog in patients with IgA nephropathy are closely associated with intrarenal arteriolar lesions.

Endothelial function, arterial stiffness and Framingham risk score in chronic kidney disease: A prospective observational cohort study

Proteomic profiling of IgA nephropathy reveals distinct molecular prognostic subtypes

Deep multi-task learning for nephropathy diagnosis on immunofluorescence images

Assessment of the Added Value of Intravoxel Incoherent Motion Diffusion‐Weighted MR Imaging in Identifying Non‐Diabetic Renal Disease in Patients With Type 2 Diabetes Mellitus

Recruiting the Best Teacher Modality: A Customized Knowledge Distillation Method for if Based Nephropathy Diagnosis

Size- and density-dependent acoustic differential bioassembly of spatially-defined heterocellular architecture

Development of a high-throughput micropatterned agarose scaffold for consistent and reproducible hPSC-derived liver organoids

Sevoflurane promotes premature differentiation of dopaminergic neurons in hiPSC-derived midbrain organoids

Acoustic Fabrication of Living Cardiomyocyte-based Hybrid Biorobots

High-throughput bioengineering of homogenous and functional human-induced pluripotent stem cells-derived liver organoids via micropatterning technique

Patent bibliometric analysis for global trend of organoid technologies in the past decade

Cerebral Organoids for Modeling of HSV-1-Induced-Amyloid β Associated Neuropathology and Phenotypic Rescue

Conductive, Injectable, and Spinnable Aniline Tetramer-Modified Polysaccharide Hydrogels for Self-Powered Electrically Responsive Drug Release

Genome-wide association study of SNP- and gene-based approaches to identify susceptibility candidates for lupus nephritis in the Han Chinese population

Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment

A Prediction Model for Acute Kidney Injury in Adult Patients With Minimal Change Disease

New Diagnostic Model for the Differentiation of Diabetic Nephropathy From Non-Diabetic Nephropathy in Chinese Patients

运动相关创伤性脑损伤的新兴三维体外模型研究进展

[Recent advances in emerging three-dimensional in vitro models for sport-related traumatic brain injury].

Editorial: 3D Cell Culture Systems for Cardiovascular Tissue Engineering: In vitro Modelling and in vivo Regenerative Therapies

Multi-Task Learning-Based Immunofluorescence Classification of Kidney Disease

The weak correlation between serum vitamin levels and chronic kidney disease in hospitalized patients: a cross-sectional study

Activated mesangial cells induce glomerular endothelial cells proliferation in rat anti‐Thy‐1 nephritis through VEGFA/VEGFR2 and Angpt2/Tie2 pathway

Krϋppel‐like factor 15 suppresses renal glomerular mesangial cell proliferation via enhancing P53 SUMO1 conjugation

Enhancing cell packing in buckyballs by acoustofluidic activation

Aligned soy protein isolate-modified poly(L-lactic acid) nanofibrous conduits enhanced peripheral nerve regeneration

Soft Robotics: Soft Ring‐Shaped Cellu‐Robots with Simultaneous Locomotion in Batches (Adv. Mater. 8/2020)

Multiscale brain research on a microfluidic chip

[Clinical characteristics and related factors of acute tubular necrosis in patients with minimal change disease].

GLA missense and promoter variants co-segregating in a Chinese family with Fabry disease.

Delivery of MSCs with a Hybrid β-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy

Delivery of MSCs with a Hybrid β-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy [Corrigendum]

Relationship between serum C3/C4 ratio and prognosis of immunoglobulin A nephropathy based on propensity score matching

Analysis of clinical and laboratory characteristics and pathology of lupus nephritis-based on 710 renal biopsies in China

Global Trends of Organoid and Organ-On-a-Chip in the Past Decade: A Bibliometric and Comparative Study

Rheological and ion-conductive properties of injectable and self-healing hydrogels based on xanthan gum and silk fibroin

Emerging organoid models: leaping forward in cancer research

Soft Ring‐Shaped Cellu‐Robots with Simultaneous Locomotion in Batches

Diagnostic efficacy of serum anti-phospholipase A2 receptor antibodies for idiopathic membranous nephropathy in patients with diabetic kidney disease.

Mitochondrial outer membrane voltage-dependent anion channel is involved in renal dysfunction in a spontaneously hypertensive rat carrying transfer RNA mutations.

Predictive Capabilities of Three Widely Used Pathology Classification Systems and a Simplified Classification (Beijing Classification) in Primary IgA Nephropathy

Commentary: Human brain organoid-on-a-chip to model prenatal nicotine exposure

Clinicopathological Features to Predict Progression of IgA Nephropathy with Mild Proteinuria

SP059 HEPARANASE A KEY REGULATOR OF THE CHRONIC PROFIBROTIC KIDNEY DAMAGE FOLLOWING ISCHEMIA/ REPERFUSION INJURY

SP142CLINICAL AND PROGNOSTIC CHARACTERISTICS OF NOCARDIOSIS IN PATIENTS ON LONG-TERM IMMUNOSUPPRESSIVE AGENTS TREATMENT

Analysis of related factors of acute kidney injury in adult minimal change nephrotic syndrome

SP062KIDNEY DISEASES IN ELDERLY: RENAL BIOPSY DATA FROM 768 PATIENTS IN ONE SINGLE CHINESE CENTER OVER 30 YEARS

Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue

Enhanced Peripheral Nerve Regeneration by a High Surface Area to Volume Ratio of Nerve Conduits Fabricated from Hydroxyethyl Cellulose/Soy Protein Composite Sponges

Efficacy and safety of calcineurin inhibitor treatment for IgA nephropathy: a meta-analysis