百晓学者学者目录

曹灿

副教授、博士生导师、教授、研究员，中国科学技术大学

精选作品

期刊论文

2026

Structural insights into the ligand modulation of MRGPRX4 conformational plasticity

Mengna Zhang, Yongxia Wang, Yun Huang, Yaqi Liang, Pengxiao Chen, Zheng Ji, Minghu Song, He Chen, Chunyu Wang, Can Cao

Cell Discovery

DOI

2026

Structural basis of LY334370 recognition and selectivity at the 5-HT1F receptor

Yumeng Wang, Chunyu Wang, Chunyu Wang, Can Cao

Biochemical and Biophysical Research Communications

DOI

2025

Pathway-selective 5-HT1AR agonist as a rapid antidepressant strategy

Chunyu Wang, Nan Zhang, Yujie Shao, Tao Li, Mengna Zhang, Meng Gao, Yaqi Liang, Yumeng Wang, Tian Xue, Yiming Shi, He Chen, Can Cao

Cell

DOI

2018

Proton transfer during class-A GPCR activation: do the CWxP motif and the membrane potential act in concert?

Xuejun C.Zhang, Ye Zhou, Can Cao

Biophysics Reports

2015

Thermodynamics of GPCR activation

Xuejun C.Zhang, Ye Zhou, Can Cao

Biophysics Reports

2015

Proton transfer-mediated GPCR activation

Xuejun C.Zhang, Can Cao, Ye Zhou, Yan Zhao

Protein & Cell

2013

GPCR activation:protonation and membrane potential

Xuejun C.Zhang, Kening Sun, Laixing Zhang, Xuemei Li, Can Cao

Protein & Cell

研究方向

免疫与精神疾病GPCR结构药理学GPCR靶向药物发现

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