百晓学者学者目录

赵国屏

教授，复旦大学

精选作品

期刊论文

2026

微生物资源研究的时代机遇与发展方向

赵国屏

《微生物学报》

2026

从“经验试错”向“理性设计”的生命科学创新逻辑演进

赵国屏

《生命科学》

2026

Engineering organoids toward implantable living therapeutics

Zhichen Shi, Qianrong Yang, Xiaoyan You, Hui Wang, Han Wang, Guoping Zhao

hLife

DOI

2026

On-chip hydrogel microfibers for biomedical sensing applications

Qianrong Yang, Zhi-Cheng Shi, Guoping Zhao, Hui Wang

Engineered Regeneration

DOI

2026

DeepSeMS: revealing the hidden biosynthetic potential of the global ocean microbiome with a large language model

Tingjun Xu, Yuwei Yang, Rui-Xin Zhu, Wei-Li Lin, Jixuan Li, Yan Zheng, Peng Zhang, Guoqing Zhang, Guoping Zhao, Na Jiao

Nature Computational Science

DOI

2026

Invasive non-typhoidal Salmonella infections in China (1961–2024): a retrospective systematic analysis of multicentre case reports

Hai-Yang Zhou, Cheng-Hao Jia, Qianzhe Cao, Linlin Huang, Lin Teng, Zi-Ning Wang, Chenghu Huang, Fang He, Yan Li, Guoping Zhao, Min Yue

Journal of Global Health

DOI

2026

CEN-Display: Construction and optimization of a surface display system in Saccharomyces cerevisiae CEN.PK2-1C.

Zhengzheng Li, Bei Zhang, Meizi Liu, C. Deng, Xinyu Wu, Li-Xia Wang, K. Verstrepen, Guoping Zhao, Yan-Fei Zhang

Bioresource Technology

DOI

2026

One Health genomics reveals niche-specific lineage replacement in Salmonella Enteritidis

Hai-Yang Zhou, Linlin Huang, J. Gong, Cheng-Hao Jia, Qianzhe Cao, Zubin Wang, Yan Song, Jiaqi Chen, Aizhong Chen, Yi Zhang, Abdelaziz Ed-Dra, Yan Li, Guoping Zhao, Min Yue

National Science Review

DOI

2026

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae : Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao

Advanced Science

DOI

2026

Recombinant Immunogens Designed by AI Epitope Prioritization Confer Protection Against Mycobacterium tuberculosis

Ning Fang, Anke Chen, Zhifei Zhang, Menglin Ye, Jiasong Pan, Weili Huang, Decheng Wang, Zhidong Hu, Xiao‐Yong Fan, Bingdong Zhu, Ying Wang, Guoping Zhao, Lu Zhang, Jixi Li

Vaccines

DOI

2026

Ergothioneine: from biosynthesis to sustainable biomanufacturing and health applications

Junjun Yan, Huaming Dong, Jiaxing Hao, Yuyue Ma, Zhao Guoping, Yanfei Zhang

Biotechnology Advances

DOI

2025

序言

张国庆，赵国屏

《生命科学》

DOI

2025

水圈微生物组大数据平台：驱动数据密集型研究范式转型的体系化实践

张国庆，刘婉，吴祉乐，周成效，李强，沈东婧，赵国屏

《生命科学》

DOI

2025

序

赵国屏

《生命科学》

DOI

2025

古菌功能演化与真核生物起源

卢中一，东秀珠，申玉龙，曾芝瑞，荆新云，周瑾洁，邹大雨，戴欣，李之萌，郑小伟，祁磊，宋宁，黄奇洪，李洁，郑峰峰，杨威，李凌燕，佘群新，黄力，赵国屏，李猛

《中国科学:生命科学》

2025

Organoids-on-Chips Technology: Unveiling New Perspectives in Rare-Disease Research

Xiangyang Li, Hui Wang, Xiaoyan You, Guoping Zhao

International Journal of Molecular Sciences

DOI

2025

A Comprehensive Safety Assessment of Ralstonia eutropha H16 for Food Applications: Integrating Genomic, Phenotypic, and Toxicological Analyzes

Xiaoyan You, Shuxia Song, Bing Li, Hui Wang, Le Zhang, Xiangyang Li, Junliang Chen, Zhi-Guang Zhu, Guoping Zhao

Microorganisms

DOI

2025

The sex hormone-gut microbiome axis: mechanistic drivers of sex-disparate bacterial infection outcomes and precision clinical interventions

Li Tang, Peilu Xie, Hao Wang, Xinhuizi Hong, Zhengwen Gong, Guoping Zhao, Min Yue

Clinical Microbiology Reviews

DOI

2025

Heterologous Substitution of Mycobacterium tuberculosis rRNA in Mycobacterium smegmatis and Its Impact on Antimicrobial Susceptibility

Qianwen Yue, Chan Shan, Arslan Habib, Guoping Zhao, Xiaoming Ding

Antibiotics

DOI

2025

Urban trash bins as reservoirs of multidrug-resistant Enterococcus with shared resistance genes across clinical and environmental niches

Jie Li, Xiaorui Mao, Yu Qing Song, Xiaohe Hu, Guoping Zhao, Biao Tang

Journal of Hazardous Materials

DOI

2025

Global prevalence of acquired antimicrobial resistance genes in Helicobacter pylori revealed by whole-genome sequence

Biao Tang, Yuhan Sun, Yu Song, Guoping Zhao, Min Yue

Journal of Infection

DOI

2025

Genetic determinants of Mycobacterium tuberculosis adaptation and drug efficacy during stationary phase growth

Xiaojie Shi, Kun-Xiong Shi, Fu Han, Li Wang, Xia Cai, Guoping Zhao, Wei Sha, Liang-Dong Lyu

Microbiology Spectrum

DOI

2025

Enterococcus faecalis hijacks FABP2 to activate quorum-sensing signals and aggravate Crohn’s disease by inducing gut dysbiosis

Yunwei Sun, Xi Xiao Huang, Yakun Zhang, Weiwen Bao, Zerong Lu, Wenying Zhao, Yusufu Rukeya, Ping He, Ji Qi, Sanhong Liu, Xiaoli Jiang, Ruidong Zhang, Kaiwen Yu, Difan Wang, Yiwen Sun, Guoping Zhao, Qijun Wang

Gut

DOI

2025

A recombinant BCG with surface-displayed antigen induces humoral and cellular immune responses

Jinyu Zhang, Zhidong Hu, Lixiao Xing, Zhenyan Chen, Jinchuan Xu, Qiaofeng Wu, Juan Wu, Guoping Zhao, Xiao‐Yong Fan, Liang-Dong Lyu

Scientific Reports

DOI

2025

Fasting-induced ketogenesis sensitizes bacteria to antibiotic treatment

Shujun Cui, Danyang Chong, Yixin Wang, Huixian Tong, Minggui Wang, Guoping Zhao, Liang-Dong Lyu

Cell Metabolism

DOI

2025

Characterisation of blaNDM-5-bearing IncHI2 plasmid from Escherichia fergusonii in China

Yan Shi, Yue Yang, Yu Song, Yujie Zhu, Guoping Zhao, Biao Tang

Journal of Global Antimicrobial Resistance

DOI

2025

Impact of DNA Extraction Methods on Gut Microbiome Profiles: A Comparative Metagenomic Study

Yanni Pu, Xiaofeng Zhou, Hao Cai, Tao Lou, Chenglin Liu, Mengmeng Kong, Zhonghan Sun, Yan-Ren Wang, Ruyi Zhang, Yuxuan Zhu, Ye Lin, Yuanting Zheng, Yuanting Zheng, Baoli Zhu, Zhe‐Xue Quan, Guoping Zhao, Yan Zheng, Yan Zheng

Phenomics

DOI

2025

Recent advances in the synthesis and application of biomolecular condensates

Zhongyue Li, Wei Tan, Guoping Zhao, Xiangze Zeng, Wei Zhao

Journal of Biological Chemistry

DOI

2024

合成生物学赋能：从学科发展到产业转化

熊燕，马雪晴，陈大明，刘晓，赵国屏

《中国科学院院刊》，Vol. 39, No. 5

下载原文

2024

[Advances of gut-on-a-chip for exploring host-microbe interactions].

Xiangyang Li, Pengcheng Shi, Le Zhang, Hui Wang, Xiaoyan You, Guoping Zhao

Sheng wu gong cheng xue bao = Chinese journal of biotechnology

DOI

2024

Harnessing the power of artificial intelligence for human living organoid research

Hui Wang, Xiangyang Li, Xiaoyan You, Guoping Zhao

Bioactive Materials

DOI

2024

Ginsenoside Rb1 improves human nonalcoholic fatty liver disease with liver organoids-on-a-chip

Hui Wang, Yue Zhu, Pengcheng Shi, Xiangyang Li, Qing-Yun Bu, Ya-chun Li, Xiaoyan You, Guoping Zhao

Engineered Regeneration

DOI

2024

Establishment and evaluation of on-chip intestinal barrier biosystems based on microfluidic techniques

Hui Wang, Xiangyang Li, Pengcheng Shi, Xiaoyan You, Guoping Zhao

Materials Today Bio

DOI

2024

Nationwide trends and features of human salmonellosis outbreaks in China

Zi-Ning Wang, Hai-Yang Zhou, Yuhao Liu, Chenghu Huang, Jiaqi Chen, A. Siddique, Rui Yin, Cheng-Hao Jia, Yan Li, Guoping Zhao, Min Yue

Emerging Microbes and Infections

DOI

2024

Genomic investigation and nationwide tracking of pediatric invasive nontyphoidal Salmonella in China

Ye-Fang Ke, Lin Teng, Zhe Zhu, Wen-Bo Lu, Wen-Yuan Liu, Hai-Yang Zhou, Qi Yu, Li-Na Ye, Pan Zhu, Guoping Zhao, Min Yue

mLife

DOI

2024

Impact of COVID-19-related Nonpharmaceutical Interventions on Diarrheal Diseases and Zoonotic Salmonella

Linlin Huang, Hai-Yang Zhou, Jiaqi Chen, Cheng-Hao Jia, A. Siddique, Bei-Bei Wu, Hao-Qiu Wang, Biao Tang, Fang He, Guoping Zhao, Min Yue

hLife

DOI

2024

Bacterial exonuclease III expands its enzymatic activities on single-stranded DNA

Hao Wang, Chen Ye, Qi Lu, Zhijie Jiang, Chao Jiang, Chun Zhou, Na Li, Caiqiao Zhang, Guoping Zhao, Min Yue, Yan Li

eLife

DOI

2024

Navigating the B vitamins: Dietary diversity, microbial synthesis, and human health

Yudie Yang, Yize Ke, Xinyan Liu, Zhidong Zhang, Rongji Zhang, Fang Tian, Luqian Zhi, Guoping Zhao, Bomin Lv, Sha Hua, Hao Wu

Cell Host & Microbe

DOI

2024

In vivo assembly of complete eukaryotic nucleosomes and (H3-H4)-only non-canonical nucleosomal particles in the model bacterium Escherichia coli

Xiaojuan Zhou, Niubing Zhang, Jie Gong, Kaixiang Zhang, Ping Chen, Xiang Lin Cheng, Bang‐Ce Ye, Guoping Zhao, Xinyun Jing, Xuan Li

Communications Biology

DOI

2024

Structural basis of the monkeypox virus mRNA cap N7 methyltransferase complex

Anke Chen, Ning Fang, Zhifei Zhang, Yiqing Wen, Yajie Shen, Yanjie Zhang, Lu Zhang, Guoping Zhao, Jin Ding, Jixi Li

Emerging Microbes & Infections

DOI

2024

MASH‐Ocean 1.0: Interactive platform for investigating microbial diversity, function, and biogeography with marine metagenomic data

Yinzhao Wang, Liuyang Li, Qiang Li, Yaoxun Hu, Wenjie Li, Zhile Wu, Hungchia Huang, Zhenbo Lv, Wan Liu, Ruifang Cao, Guoping Zhao, Yinzhao Wang, Guoqing Zhang

iMeta

DOI

2024

Advance typing of Vibrio parahaemolyticus through the mtlA and aer gene: A high-resolution, cost-effective approach

Lei Zhou, Danlei Liu, Yongqiang Zhu, Zilong Zhang, Shiwen Chen, Guoping Zhao, Huajun Zheng

Heliyon

DOI

2024

Reduced clinical severity during 2022 Shanghai Spring epidemic of SARS-CoV-2 omicron BA.2 variant infection—an integrated account of virus pathogenicity and vaccination effectiveness

Xingyue Wu, Yao Chen, Kangli Cao, Yao Shen, Xueling Wu, Yilin Yang, Zhongshu Kuang, Qingrun Li, Zhen-Zhen Lu, Yichen Jia, Mian Shao, Guorong Gu, Xiangwei Wang, Ye Yao, Ying Wang, Shaodie Chen, Zhigao Yu, Wei Wei, Longfei Ding, Lulu Lan, Tianwen Gu, Xiangyu Long, Jian Sun, Lingyu Xing, Jia‐Yuan Shen, Yi Han, Yue Luo, Sucheng Mu, Mengna Lin, Xiaoyan Zhang, Rong Zeng, Jianqing Xu, Guoping Zhao, Lihong Huang, Zhenju Song

National Science Review

DOI

2023

生物医学大数据生产要素价值的实现：从数据元素起步

张国庆，赵国屏，李亦学

《生命科学》

2023

会聚研究内核与赋能人类潜质——合成生物学的机遇和挑战

赵国屏

《张江科技评论》

2023

合成生物学2035发展战略

赵国屏

《世界科学》

2023

基于人工智能和计算生物学的合成生物学元件设计

王晟，王泽琛，陈威华，陈珂，彭向达，欧发芬，郑良振，孙瑨原，沈涛，赵国屏

《合成生物学》

2023

Transcriptional Self-Regulation of the Master Nitrogen Regulator GlnR in Mycobacteria

Juanmei He, Xiaoman Kang, Jia-Cheng Wu, Zhihui Shao, Zhenhua Zhang, Yuqian Wu, Hua Yuan, Guo-Ping Zhao, Jin Wang

Journal of Bacteriology

DOI

2023

Acetylation coordinates the crosstalk between carbon metabolism and ammonium assimilation in Salmonella enterica

Yun-wei Sun, Yuebin Zhang, Ting Zhao, Yi Luan, Ying Wang, Chen Yang, B. Shen, Xi Huang, Guohui Li, Shimin Zhao, Guo-Ping Zhao, Qi-Jun Wang

EMBO Journal

DOI

2023

Genome degradation promotes Salmonella pathoadaptation by remodeling fimbriae-mediated proinflammatory response

Xiao Zhou, Xiamei Kang, Jiaqi Chen, Yan Song, Chenghao Jia, Lin Teng, Yanting Tang, Zhijie Jiang, Xianqi Peng, Xiaoxia Tao, Yi-Wei Xu, Linlin Huang, Xue-Bin Xu, Yao-Hui Xu, Tengfei Zhang, Shenye Yu, J. Gong, Shaohui Wang, Yu-Qing Liu, Guoqiang Zhu, C. Kehrenberg, F. Weill, P. Barrow, Yan Li, Guoping Zhao, Min Yue

National Science Review

DOI

2023

An integrated nationwide genomics study reveals transmission modes of typhoid fever in China

Ye Feng, Hang Pan, B. Zheng, Fang Li, Lin Teng, Zhijie Jiang, Mengyao Feng, Xiao Zhou, Xianqi Peng, Xue-Bin Xu, Hao-Qiu Wang, Bei-Bei Wu, Yong-Hong Xiao, Stephen Baker, Guoping Zhao, Min Yue

mBio

DOI

2023

CRISPR-Cas9 Mediated Stable Expression of Exogenous Proteins in the CHO Cell Line through Site-Specific Integration

Zhipeng Huang, Arslan Habib, Guoping Zhao, Xiaoming Ding

International Journal of Molecular Sciences

DOI

2023

Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism

Luyao Bao, Juan Hu, Bowen Zhan, Mingzhe Chi, Zhengyang Li, Sen Wang, Chan Shan, Zhaozhao Zhao, Yanchao Guo, Xiaoming Ding, Chaoneng Ji, Sheng‐ce Tao, Ting Ni, Xuelian Zhang, Guoping Zhao, Jixi Li

Nature Communications

DOI

2023

Genome-wide screen reveals cellular functions that counteract rifampicin lethality in Escherichia coli

Yu Wang, Han Fu, Xiaojie Shi, Guoping Zhao, Liang-Dong Lyu

Microbiology Spectrum

DOI

2023

Ginsenoside compound-K attenuates OVX-induced osteoporosis via the suppression of RANKL-induced osteoclastogenesis and oxidative stress

Lingli Ding, Zhao Gao, Siluo Wu, Chen Chen, Yamei Liu, Min Wang, Yage Zhang, Ling Li, Hong Zou, Guoping Zhao, Shengnan Qin, Liangliang Xu

Natural Products and Bioprospecting

DOI

2023

Human Gut Microbiome Researches Over the Last Decade: Current Challenges and Future Directions

Hao Wu, Sofia Kirke Forslund, Zeneng Wang, Guoping Zhao

Phenomics

DOI

2023

A follow-up study on the recovery and reinfection of Omicron COVID-19 patients in Shanghai, China

Mengna Lin, Kangli Cao, Feixiang Xu, Xueling Wu, Yao Shen, Su Lü, Zhongshu Kuang, Hailin Ding, Shuyun Yuan, Mian Shao, Guorong Gu, Lingyu Xing, Tianwen Gu, Shaodie Chen, Jian Sun, Jiamin Zhu, Xiaoyan Zhang, Yilin Yang, Guoping Zhao, Lihong Huang, Jianqing Xu, Zhenju Song

Emerging Microbes & Infections

DOI

2023

Scaffold-Scaffold Interaction Facilitates Cell Polarity Development in Caulobacter crescentus

Ning Lü, Samuel W. Duvall, Guohong Zhao, Kimberley A. Kowallis, Chao Zhang, Wei Tan, Jingxian Sun, Haley N. Petitjean, Dylan T. Tomares, Guoping Zhao, W. Seth Childers, Wei Zhao

mBio

DOI

2023

Sample Collection, DNA Extraction, and Library Construction Protocols of the Human Microbiome Studies in the International Human Phenome Project

Yetong Wang, Ruyi Zhang, Yanni Pu, Danqi Wang, Yan-Ren Wang, Xuemei Wu, Yujie Pan, Luo Chen, Guoping Zhao, Zhe‐Xue Quan, Yan Zheng

Phenomics

DOI

2023

Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis

Sen Wang, Baocai Gao, Anke Chen, Zhifei Zhang, Sheng Wang, Liangdong Lv, Guoping Zhao, Jixi Li

Frontiers in Microbiology

DOI

2023

Disruption of hrcA, the repression gene of groESL and rpoH, enhances heterologous biosynthesis of the nonribosomal peptide/polyketide compound epothilone in Schlegelella brevitalea

Huimin Wang, Yan Shi, Junheng Liang, Guoping Zhao, Xiaoming Ding

Biochemical Engineering Journal

DOI

2023

RT-RPA-Cas12a-based assay facilitates the discrimination of SARS-CoV-2 variants of concern

Guiyue Tang, Zilong Zhang, Wei Liang Tan, Fei Long, Jingxian Sun, Yingying Li, Siwei Zou, Yujiao Yang, Kezhu Cai, Shenwei Li, Zhiyi Wang, Jiakun Liu, Guobing Mao, Yingxin Ma, Guoping Zhao, Zhengan Tian, Wei Zhao

Sensors and Actuators B Chemical

DOI

2022

VENAS：新冠病毒大规模基因组进化网络的快速分析方法（英文）

凌鋆超，曹瑞芳，钱嘉强，李杰夫，周豪魁，袁力贇，王振，马良宵，郑广勇，赵国屏，王泽峰，张国庆，李亦学

Science Bulletin

2022

临床研究大数据治理平台的建设与实践

潘逸航，郑子龙，张国庆，赵国屏，何裕隆

《中国卫生信息管理杂志》

2022

合成生物学：从“造物致用”到产业转化

赵国屏

《生物工程学报》

2022

合成生物学时代的生物安全治理

刘晓，汪哲，陈大明，熊燕，赵国屏

《科学与社会》

2022

Phase separation modulates the assembly and dynamics of a polarity-related scaffold-signaling hub

Wei Tan, Sihua Cheng, Yingying Li, Xiaoyang Li, Ning Lu, Jingxian Sun, Guiyue Tang, Yujiao Yang, Kezhu Cai, Xuefei Li, Xijun Ou, Xiang Gao, Guoping Zhao, W. Seth Childers, Wei Zhao

Nature Communications

DOI

2022

An interactive viral genome evolution network analysis system enabling rapid large-scale molecular tracing of SARS-CoV-2

Yunchao Ling, Ruifang Cao, Jiaqiang Qian, Jiefu Li, Haokui Zhou, Liyun Yuan, Zhen Wang, Zhen Wang, Liangxiao Ma, Guangyong Zheng, Guoping Zhao, Zefeng Wang, Zefeng Wang, Guoqing Zhang, Yixue Li

《中国科学通报：英文版》

DOI

2022

Display of receptor-binding domain of SARS-CoV-2 Spike protein variants on the Saccharomyces cerevisiae cell surface

Hongguan Xing, Liyan Zhu, Pingping Wang, Guoping Zhao, Zhihua Zhou, Yi An Yang, Hong Zou, Xing Yan

Frontiers in Immunology

DOI

2022

Corrigendum: Ginsenoside Compound K Enhances Fracture Healing via Promoting Osteogenesis and Angiogenesis

Lingli Ding, Song Gu, Bingyu Zhou, Min Wang, Yage Zhang, Siluo Wu, Hong Zou, Guoping Zhao, Zhao Gao, Liangliang Xu

Frontiers in Pharmacology

DOI

2022

Detecting Genetic Variation of Colonizing Streptococcus agalactiae Genomes in Humans: A Precision Protocol

Yan Zhou, Xue-Chao Zhao, Linqi Wang, Chengwen Chen, Mei‐Hua Hsu, Wan-Ting Liao, Xiao Deng, Qing Yan, Guoping Zhao, Chyi‐Liang Chen, Liang Zhang, Cheng‐Hsun Chiu

Frontiers in Bioinformatics

DOI

2022

Ginsenoside Rb1 Improves Metabolic Disorder in High-Fat Diet-Induced Obese Mice Associated With Modulation of Gut Microbiota

Hong Zou, Man Zhang, Xiaoting Zhu, Liyan Zhu, Shuo Chen, Mingjing Luo, Qinglian Xie, Yue Chen, Kangxi Zhang, Qingyun Bu, Yuchen Wei, Ye Tao, Qiang Li, Xing Yan, Zhihua Zhou, Chen Yang, Yu Li, Haokui Zhou, Chenhong Zhang, Xiaoyan You, Guangyong Zheng, Guoping Zhao

Frontiers in Microbiology

DOI

2022

Ginsenoside Compound K Enhances Fracture Healing via Promoting Osteogenesis and Angiogenesis

Lingli Ding, Song Gu, Bingyu Zhou, Min Wang, Yage Zhang, Siluo Wu, Hong Zou, Guoping Zhao, Zhao Gao, Liangliang Xu

Frontiers in Pharmacology

DOI

2021

从人类基因组计划到精准医学——比较医学的发展趋势与挑战

赵国屏

《实验动物与比较医学》

2021

新型冠状病毒基因组的演化分析及谱系划分（英文）

唐小鹿，应若晨，姚欣敏，李广浩，吴长城，汤易雨立，李志达，邝碧姗，伍锋，池昌盛，杜晓满，覃依，高胜寒，胡松年，马俊才，刘天罡，庞星火，王建伟，赵国屏，谭文杰，张亚平，吕雪梅，陆剑

Science Bulletin

2021

行至半山坡更陡认识合成生物学发展的关键节点

赵国屏

《生命科学》

DOI

2021

合成生物学的科学问题

罗楠，赵国屏，刘陈立

《生命科学》

DOI

2021

我国迎来定量合成生物学发展重要契机

赵国屏，刘陈立，赵广立

《中国科学报》

2021

50岁转行，为关键大事发光发热

赵国屏，黄海华

《解放日报》

2021

Unbalanced dietary patterns contribute to the pathogenesis of precocious puberty by affecting gut microbiota and host metabolites

Ying Wang, Ding-Feng Wu, Hongying Li, Xian-quan Liang, Na Jiao, Wen-Xing Gao, Lu Zhao, Han Yu, Qian Wang, Yongsheng Ge, Changying Zhao, Mei-Ling Huo, Ruifang Cao, Sheng Gao, Liwen Tao, Yun-Chao Ling, Ling-Nan Zhao, X. Lv, Yi Liu, Le-Hai Zhang, Hao-Kui Zhou, Guo-Qing Zhang, Guo-Ping Zhao, Lei Zhang, Rui-Xin Zhu, Z. Gai

bioRxiv

DOI

2021

Reversible regulation of Cas12a activities by AcrVA5-mediated acetylation and CobB-mediated deacetylation

X. Kang, L. Yin, Songkuan Zhuang, Tianshuai Hu, Zhi-Le Wu, Guo-Ping Zhao, Yijian Chen, Yong Xu, Jin Wang

Cell Discovery

DOI

2021

Putative Familial Transmissible Bacteria of Various Body Niches Link with Home Environment and Children’s Immune Health

Lu Zhao, Wanning Chen, Yongsheng Ge, X. Lv, Ying Wang, Han Yu, Yi Liu, Ding-Feng Wu, Na Jiao, Yuanqi Wu, Daqing Lv, Guo-Qing Zhang, Fu-Zhong Xue, Xiaohong Xu, Z. Gai, Rui-Xin Zhu, Lei Zhang, Guo-Ping Zhao

Microbiology spectrum

DOI

2021

Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity

Huimin Wang, Junheng Liang, Qianwen Yue, Long Li, Yan Shi, Guosong Chen, Yue‐zhong Li, Xiaoying Bian, Youming Zhang, Guoping Zhao, Xiaoming Ding

Microbial Cell Factories

DOI

2021

Mycobacterial fatty acid catabolism is repressed by FdmR to sustain lipogenesis and virulence

Wenyue Dong, Xiaoqun Nie, Hong Mei Zhu, Qingyun Liu, Kun-Xiong Shi, Linlin You, Yu Zhang, H. Christina Fan, Bo Yan, Chen Niu, Liang-Dong Lyu, Guoping Zhao, Chen Yang

Proceedings of the National Academy of Sciences

DOI

2020

助推合成生物学会聚研究、提升中华民族科技创新能力——《合成生物学》创刊有感

赵国屏

《合成生物学》

2020

CRISPR-Cas12a-Assisted Genome Editing in Amycolatopsis mediterranei

Ya-Juan Zhou, Xin-Qiang Liu, Jia-Cheng Wu, Guo-Ping Zhao, Jin Wang

Frontiers in Bioengineering and Biotechnology

DOI

2020

A recently evolved diflavin-containing monomeric nitrate reductase is responsible for highly efficient bacterial nitrate assimilation

Wei Tan, Tian-Hua Liao, Jin Wang, Yu Ye, Yu-Chen Wei, Hao Zhou, Youli Xiao, Xiao-Yang Zhi, Zhihui Shao, Liangdong Lyu, Guo-Ping Zhao

Journal of Biological Chemistry

DOI

2020

GlnR Dominates Rifamycin Biosynthesis by Activating the rif Cluster Genes Transcription Both Directly and Indirectly in Amycolatopsis mediterranei

Xin-Qiang Liu, Yuanyuan Liu, Chao Lei, Guo-Ping Zhao, Jin Wang

Frontiers in Microbiology

DOI

2020

Reassembly of the biosynthetic gene cluster enables high epothilone yield in engineered Schlegelella brevitalea.

Yu-Cong Yu, Hui-Min Wang, Biao Tang, Junheng Liang, Lin Zhang, Hongkuan Wang, Xiao-Ying Bian, Yue-Zhong Li, You-Ming Zhang, Guo-Ping Zhao, Xiao-Ming Ding

ACS Synthetic Biology

DOI

2020

Deacetylation enhances ParB–DNA interactions affecting chromosome segregation in Streptomyces coelicolor

Peng Li, Hong Zhang, Guoping Zhao, Wei Zhao

Nucleic Acids Research

DOI

2020

Heterologous redox partners supporting the efficient catalysis of epothilone B biosynthesis by EpoK in Schlegelella brevitalea

Junheng Liang, Huimin Wang, Xiaoying Bian, Youming Zhang, Guoping Zhao, Xiaoming Ding

Microbial Cell Factories

DOI

2019

CRISPR技术在生物传感中的应用——胞内核酸成像、体外核酸检测与胞内DNA记录

李诗渊，赵国屏，王金

《生物产业技术》

2019

合成生物学——生物工程产业化发展的新时期

赵国屏

《生物产业技术》

2019

编者按

赵国屏

《中国细胞生物学学报》

2019

基因合成与基因组编辑

刘晓，王慧媛，熊燕，赵国屏，王金

《中国细胞生物学学报》

2019

HOLMESv2: a CRISPR-Cas12b-assisted platform for nucleic acid detection and DNA methylation quantitation.

Linxian Li, Shi-Yuan Li, Na Wu, Jia-Cheng Wu, Gang Wang, Guo-Ping Zhao, Jin Wang

ACS Synthetic Biology

DOI

2019

Author Correction: CRISPR-Cas12a-assisted nucleic acid detection

Shi-Yuan Li, Qiu-Xiang Cheng, Jing-Man Wang, Xiao-Yan Li, Zi-Long Zhang, Song Gao, Rui-Bing Cao, Guo-Ping Zhao, Jin Wang

Cell Discovery

DOI

2019

CRISPR/ddCas12a-based programmable and accurate gene regulation

Jing-Man Wang, A. Lu, Jin-Xin Bei, Guo-Ping Zhao, Jin Wang

Cell Discovery

DOI

2019

Reprogrammable CRISPR/dCas9-based recruitment of DNMT1 for site-specific DNA demethylation and gene regulation

A. Lu, Jing-Man Wang, Wei-Hong Sun, Wei-Ren Huang, Zhi-Ming Cai, Guo-Ping Zhao, Jin Wang

Cell Discovery

DOI

2019

Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment

Ning Li, Junjie Yang, Jiaming Zhang, Cheng Liang, Ying Wang, Bin Chen, Changying Zhao, Jingwen Wang, Guangye Zhang, Dong-Mei Zhao, Yi Liu, Le-Hai Zhang, Jun Yang, Guimei Li, Z. Gai, Lei Zhang, Guo-Ping Zhao

Genomics, Proteomics & Bioinformatics

DOI

2019

Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor

Juncao Xu, Kaijie Cui, Liqiang Shen, Jing Shi, Lingting Li, Linlin You, Chengli Fang, Guoping Zhao, Yu Feng, Bei Yang, Yu Zhang

eLife

DOI

2019

tmap: an integrative framework based on topological data analysis for population-scale microbiome stratification and association studies

Tianhua Liao, Yuchen Wei, Mingjing Luo, Guoping Zhao, Haokui Zhou

Genome biology

DOI

2019

Modification of the genome topology network and its application to the comparison of group B Streptococcus genomes

Xiao Jun Deng, Xuechao Zhao, Yuan Liang, Liang Zhang, Jianping Jiang, Guoping Zhao, Yan Zhou

BMC Genomics

DOI

2019

Author response: Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor

Juncao Xu, Kaijie Cui, Liqiang Shen, Jing Shi, Lingting Li, Linlin You, Chengli Fang, Guoping Zhao, Yu Feng, Bei Yang, Yu Zhang

DOI

2019

ScCobB2-mediated Lysine Desuccinylation Regulates Protein Biosynthesis and Carbon Metabolism in Streptomyces coelicolor*[S]

Hong Zhang, Peng Li, Shuangxi Ren, Zhongyi Cheng, Guoping Zhao, Wei Zhao

Molecular & Cellular Proteomics

DOI

2019

Efficient circular gene knockout system for strain DSM 7029 and mc 155

Xiaolai Lei, Qiuxia Fan, Tian Jun Huang, Haiyun Liu, Guoping Zhao, Xiaoming Ding

Acta Biochimica et Biophysica Sinica

DOI

2018

生物医学大数据发展的新挑战与趋势

张国庆，李亦学，王泽峰，赵国屏

《中国科学院院刊》，Vol. 33, No. 8

下载原文

2018

中国微生物组计划:机遇与挑战

刘双江，施文元，赵国屏

《中国农业文摘-农业工程》

2018

雨生红球藻低覆盖度基因组草图分析

陈军，郑华军，刘亚铭，赵国屏，秦松

《中国生物工程杂志》

2018

合成生物学：开启生命科学“会聚”研究新时代

赵国屏

《中国科学院院刊》，Vol. 33, No. 11

下载原文

2018

CADS: CRISPR/Cas12a-Assisted DNA Steganography for Securing the Storage and Transfer of DNA-Encoded Information.

Shi-Yuan Li, Jia-Kun Liu, Guo-Ping Zhao, Jin Wang

ACS Synthetic Biology

DOI

2018

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

Shi-Yuan Li, Qiu-Xiang Cheng, Jia-Kun Liu, Xiaoling Nie, Guo-Ping Zhao, Jin Wang

Cell Research

DOI

2018

Deciphering the late steps of rifamycin biosynthesis

Fei-Fei Qi, Chao Lei, Fengwei Li, Xing-Wang Zhang, Jin Wang, Wei Zhang, Zhen Fan, Weichao Li, Gong-Li Tang, Youli Xiao, Guo-Ping Zhao, Shengying Li

Nature Communications

DOI

2018

CRISPR-Cas12a-assisted nucleic acid detection

Shi-Yuan Li, Qiu-Xiang Cheng, Jing-Man Wang, Xiao-Yan Li, Zi-Long Zhang, Song Gao, Rui-Bing Cao, Guo-Ping Zhao, Jin Wang

Cell Discovery

DOI

2018

GlnR positive transcriptional regulation of the phosphate-specific transport system pstSCAB in Amycolatopsis mediterranei U32

Yuhui Zhang, Yixuan Zhang, Pengfei Li, Ying Wang, Jin Wang, Zhihui Shao, Guo-Ping Zhao

Acta Biochimica et Biophysica Sinica

DOI

2018

iCatch: a new strategy for capturing large DNA fragments using homing endonucleases

Jing-Man Wang, A. Lu, Jia-Kun Liu, Wei-Ren Huang, Jin Wang, Zhi-Ming Cai, Guo-Ping Zhao

Acta Biochimica et Biophysica Sinica

DOI

2018

Insight into the Molecular Mechanism of the Transcriptional Regulation of amtB Operon in Streptomyces coelicolor

Zhen-Dong Li, Xin-Qiang Liu, Jing-Zhi Wang, Ying Wang, Guo-Song Zheng, Yin-Hua Lu, Guo-Ping Zhao, Jin Wang

Frontiers in Microbiology

DOI

2018

A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei

Chao Lei, Jing-Zhi Wang, Yuanyuan Liu, Xin-Qiang Liu, Guo-Ping Zhao, Jin Wang

Microbial Cell Factories

DOI

2018

A single circular chromosome yeast

Yangyang Shao, Ning Lü, Chen Cai, Fan Zhou, Shanshan Wang, Zhihu Zhao, Guoping Zhao, Jin‐Qiu Zhou, Xiaoli Xue, Zhongjun Qin

Cell Research

DOI

2018

Creating a functional single-chromosome yeast

Yangyang Shao, Ning Lü, Zhenfang Wu, Chen Cai, Shanshan Wang, Ling-Li Zhang, Fan Zhou, Shijun Xiao, Lin Liu, Xiaofei Zeng, Huajun Zheng, Chen Yang, Zhihu Zhao, Guoping Zhao, Jin‐Qiu Zhou, Xiaoli Xue, Zhongjun Qin

Nature

DOI

2018

The draft genomes and investigation of serotype distribution, antimicrobial resistance of group B Streptococcus strains isolated from urine in Suzhou, China

Yong Guo, Xiao Jun Deng, Yuan Liang, Liang Zhang, Guoping Zhao, Yan Zhou

Annals of Clinical Microbiology and Antimicrobials

DOI

2018

The cyanobacterial ornithine–ammonia cycle involves an arginine dihydrolase

Hao Zhang, Yujie Liu, Xiaoqun Nie, Lixia Liu, Qiang Hua, Guoping Zhao, Chen Yang

Nature Chemical Biology

DOI

2018

Site‐specificity of serine integrase demonstrated by the attB sequence preference of ɸ BT 1 integrase

Xiaolai Lei, Lu Wang, Guoping Zhao, Xiaoming Ding

FEBS Letters

DOI

2018

Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp. strain fd1-xmd

Yucong Yu, Biao Tang, Ruixue Dai, Bo Zhang, Liqiang Chen, Hua Yang, Guoping Zhao, Xiaoming Ding

Applied Microbiology and Biotechnology

DOI

2018

Identification and characterisation of bifidobacteria in infant formula milk powder obtained from the Chinese market

Yang Liu, Wenwen Chen, Yi Yu, Qingping Zhang, Qinfeng Qu, Wenfeng Duan, Yu Zhao, Weng Shiyu, Guoping Zhao, Tonghai Dou

International Dairy Journal

DOI

2018

Oxidation of dCTP contributes to antibiotic lethality in stationary-phase mycobacteria

Xiao‐Yong Fan, Bikui Tang, Yuanyuan Xu, A.D. Han, Kun-Xiong Shi, Yong-Kai Wu, Ye Yu, Meili Wei, Chen Niu, Ka‐Wing Wong, Guoping Zhao, Liang-Dong Lyu

Proceedings of the National Academy of Sciences

DOI

2017

合成生物学技术的研究进展——DNA合成、组装与基因组编辑

李诗渊，赵国屏，王金

《生物工程学报》

2017

中国微生物组计划：机遇与挑战

刘双江，施文元，赵国屏

《中国科学院院刊》，Vol. 32, No. 3

下载原文

2017

建设微生物组大数据中心发挥长期科学影响

张国庆，宁康，职晓阳，刘婉，徐萍，周豪魁，胡黔楠，赵国屏

《中国科学院院刊》，Vol. 32, No. 3

下载原文

2017

Multiplex gene regulation by CRISPR-ddCpf1

Xiao-Chun Zhang, Jing-Man Wang, Qiu-Xiang Cheng, Xuan S Zheng, Guo-Ping Zhao, Jin Wang

Cell Discovery

DOI

2017

The CCTL (Cpf1-assisted Cutting and Taq DNA ligase-assisted Ligation) method for efficient editing of large DNA constructs in vitro

Chao Lei, Shi-Yuan Li, Jia-Kun Liu, Xuan Zheng, Guo-Ping Zhao, Jin Wang

Nucleic Acids Research

DOI

2017

A Novel and Efficient Method for Bacteria Genome Editing Employing both CRISPR/Cas9 and an Antibiotic Resistance Cassette

Hong Zhang, Qiu-Xiang Cheng, Ai-Min Liu, Guo-Ping Zhao, Jin Wang

Frontiers in Microbiology

DOI

2017

[Enabling technologies in synthetic biology--DNA synthesis, assembly and editing].

Shi-Yuan Li, Guo-Ping Zhao, Jin Wang

Sheng wu gong cheng xue bao = Chinese journal of biotechnology

DOI

2017

Protocols for C-Brick DNA Standard Assembly Using Cpf1.

Shi-Yuan Li, Guo-Ping Zhao, Jin Wang

Journal of Visualized Experiments

DOI

2017

RifZ (AMED_0655) Is a Pathway-Specific Regulator for Rifamycin Biosynthesis in Amycolatopsis mediterranei

Chen Li, Xin-Qiang Liu, Chao Lei, Han Yan, Zhihui Shao, Ying Wang, Guo-Ping Zhao, Jin Wang, Xiao-Ming Ding

Applied and Environmental Microbiology

DOI

2017

Conjugation of φBT1-derived integrative plasmid pDZL802 in Amycolatopsis mediterranei U32

Chen Li, Li Zhou, Ying Wang, Guo-Ping Zhao, Xiao-Ming Ding

Bioengineered

DOI

2017

An efficient system for deletion of large DNA fragments in Escherichia coli via introduction of both Cas9 and the non-homologous end joining system from Mycobacterium smegmatis.

Xuan Zheng, Shi-Yuan Li, Guo-Ping Zhao, Jin Wang

Biochemical and Biophysical Research Communications - BBRC

DOI

2017

Morphology engineering of Streptomyces coelicolor M145 by sub-inhibitory concentrations of antibiotics

Wang Hu, Guoping Zhao, Xiaoming Ding

Scientific Reports

DOI

2017

Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029

Xiaoying Bian, Biao Tang, Yucong Yu, Qiang Tu, Frank Gross, Hailong Wang, Aiying Li, Jun Fu, Yuemao Shen, Yue‐zhong Li, Adrian Francis Stewart, Guoping Zhao, Xiaoming Ding, Rolf Müller, Youming Zhang

ACS Chemical Biology

DOI

2016

基因与基因组的精细合成原理和技术研究报告

赵国屏，王金，周湘元

《科技资讯》

2016

Direct Involvement of the Master Nitrogen Metabolism Regulator GlnR in Antibiotic Biosynthesis in Streptomyces*

Juanmei He, Hong Zhu, Guo-Song Zheng, Pan Liu, Jin Wang, Guo-Ping Zhao, Guo-qiang Zhu, Wei-Fang Jiang, Yin-Hua Lu

Journal of Biological Chemistry

DOI

2016

Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli

Qiu-Fen Zhang, A. Zhou, Shu-Xian Li, Jin-Jing Ni, Jing Tao, Jie Lu, Bao-Shan Wan, Shuai Li, Jian Zhang, Shimin Zhao, Guo-Ping Zhao, F. Shao, Yu-Feng Yao

Scientific Reports

DOI

2016

C-Brick: A New Standard for Assembly of Biological Parts Using Cpf1.

Shi-Yuan Li, Guo-Ping Zhao, Jin Wang

ACS Synthetic Biology

DOI

2016

Characterization of the Ca2+‐responsive signaling pathway in regulating the expression and secretion of cellulases in Trichoderma reesei Rut‐C30

Ling Chen, Gen Zou, Jing-Zhi Wang, Jin Wang, Rui Liu, Yanping Jiang, Guo-Ping Zhao, Zhi-Hua Zhou

Molecular Microbiology

DOI

2016

Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket*

Xiaobiao Han, Li-Qiang Shen, Qi-Jun Wang, Xufeng Cen, Jin Wang, Meng Wu, Peng Li, Wei Zhao, Yu Zhang, Guo-Ping Zhao

Journal of Biological Chemistry

DOI

2016

Alpha-ketoglutarate protects Streptomyces coelicolor from visible light-induced phototoxicity

Feng Xu, Jin Wang, Guo-Ping Zhao

Biochemistry and Biophysics Reports

DOI

2016

Molecular evidence for the coordination of nitrogen and carbon metabolisms, revealed by a study on the transcriptional regulation of the agl3EFG operon that encodes a putative carbohydrate transporter in Streptomyces coelicolor.

Xu-Feng Cen, Jing-Zhi Wang, Guo-Ping Zhao, Ying Wang, Jin Wang

Biochemical and Biophysical Research Communications - BBRC

DOI

2016

Bxb1 integrase serves as a highly efficient DNA recombinase in rapid metabolite pathway assembly

Xianwei Wang, Biao Tang, Yu Ye, Yayi Mao, Xiaolai Lei, Guoping Zhao, Xiaoming Ding

Acta Biochimica et Biophysica Sinica

DOI

2016

The genome of serotype VI Streptococcus agalactiae serotype VI and comparative analysis

En-Ming He, Chengwen Chen, Yong Guo, Mei‐Hua Hsu, Liang Zhang, Hsiu‐Ling Chen, Guoping Zhao, Cheng‐Hsun Chiu, Yan Zhou

Gene

DOI

2016

A systematic study of the whole genome sequence of Amycolatopsis methanolica strain 239 T provides an insight into its physiological and taxonomic properties which correlate with its position in the genus

Biao Tang, Feng Xie, Wei Zhao, Jian Wang, Shengwang Dai, Huajun Zheng, Xiaoming Ding, Xufeng Cen, Haican Liu, Yucong Yu, Haokui Zhou, Yan Zhou, Lixin Zhang, Michael Goodfellow, Guoping Zhao

Synthetic and Systems Biotechnology

DOI

2015

从生命分子的人工合成到合成生命——人工合成胰岛素事业在新时代的继承及超越

赵国屏

《生命科学》

2015

合成生物学的发展:我国面临的机遇与挑战

熊燕，刘晓，赵国屏

《科学与社会》

2015

合成生物学——革命性的新兴交叉学科,“会聚”研究范式的典型

赵国屏

《中国科学:生命科学》

2015

A preliminary study of the mechanism of nitrate-stimulated remarkable increase of rifamycin production in Amycolatopsis mediterranei U32 by RNA-seq

Zhihui Shao, Shuang-Xi Ren, Xin-Qiang Liu, Jian Xu, Han Yan, Guo-Ping Zhao, Jin Wang

Microbial Cell Factories

DOI

2015

Precise characterization of GlnR Box in actinomycetes.

Jin Wang, Ying Wang, Guo-Ping Zhao

Biochemical and Biophysical Research Communications - BBRC

DOI

2015

GlnR-Mediated Regulation of ectABCD Transcription Expands the Role of the GlnR Regulon to Osmotic Stress Management

Zhihui Shao, Wanxin Deng, Shi-Yuan Li, Juanmei He, Shuang-Xi Ren, Wei-Ren Huang, Yin-Hua Lu, Guo-Ping Zhao, Zhi-Ming Cai, Jin Wang

Journal of Bacteriology

DOI

2015

["Nitrate stimulating effect" in Amycolatopsis mediterranei--from discovery to mechanistic studies].

Zhihui Shao, Zhao Wei, Y. Wang, Xiao-Ming Ding, Jin Wang, Wei-Hong Jiang, Guo-Ping Zhao

Sheng wu gong cheng xue bao = Chinese journal of biotechnology

2015

Identification of three extra-chromosomal replicons in Leptospira pathogenic strain and development of new shuttle vectors

Wei-Nan Zhu, Jin Wang, Yong-Zhang Zhu, Biao Tang, Yun-Yi Zhang, P. He, Yan Zhang, Bo-Yu Liu, Xiao-Kui Guo, Guo-Ping Zhao, Jin-Hong Qin

BMC Genomics

DOI

2015

Complete genome sequence of the glidobactin producing strain [Polyangium] brachysporum DSM 7029

Biao Tang, Yucong Yu, Youming Zhang, Guoping Zhao, Xiaoming Ding

Journal of Biotechnology

DOI

2015

Site‐specific recombination for cloning of large DNA fragments in vitro

Ruixue Dai, Bo Zhang, Guoping Zhao, Xiaoming Ding

Engineering in Life Sciences

DOI

2015

Production of bioactive ginsenosides Rh2 and Rg3 by metabolically engineered yeasts

Pingping Wang, Yongjun Wei, Yun Fan, Qunfang Liu, Wei Wei, Chengshuai Yang, Lei Justan Zhang, Guoping Zhao, Jian‐Min Yue, Xing Yan, Zhihua Zhou

Metabolic Engineering

DOI

2015

Comparing Mycobacterium tuberculosis genomes using genome topology networks

Jianping Jiang, Jianlei Gu, Liang Zhang, Chenyi Zhang, Xiao Deng, Tonghai Dou, Guoping Zhao, Yan Zhou

BMC Genomics

DOI

2015

Streptomyces yangpuensis sp. nov., isolated from soil

Biao Tang, Yucong Yu, Xiao‐Yang Zhi, Ling‐Ling Yang, Xufeng Cen, Guoping Zhao, Xiaoming Ding

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

DOI

2015

Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy

Bin Zhou, Hui Dong, Yungang He, Jian Sun, Weirong Jin, Qing Xie, Rong Fan, Minxian Wang, Ran Li, Yangyi Chen, Shaoqing Xie, Yan Shen, Xin Huang, Shengyue Wang, LU Feng-ming, Jidong Jia, Hui Zhuang, STEPHEN A LOCARNINI, Guoping Zhao, Jin Li, Jinlin Hou

Scientific Reports

DOI

2015

Draft Genome Sequence of the Streptothricin-Producing Strain Streptomyces sp. fd2-tb

Biao Tang, Yucong Yu, Xufeng Cen, Yongqiang Zhu, Ruixue Dai, Xianwei Wang, Guoping Zhao, Xiaoming Ding

Genome Announcements

DOI

2015

Gossypium barbadense genome sequence provides insight into the evolution of extra-long staple fiber and specialized metabolites

Xia Liu, Bo Zhao, Huajun Zheng, Yan Hu, Gang Lü, Changqing Yang, Jiedan Chen, Jun-Jian Chen, Dian-Yang Chen, Liang Zhang, Yan Zhou, Ling-Jian Wang, Wangzhen Guo, Yulin Bai, Ju-Xin Ruan, Xiao‐Xia Shangguan, Ying‐Bo Mao, Chun‐Min Shan, Jianping Jiang, Yongqiang Zhu, Lei Jin, Hui Kang, Shuting Chen, Xu-Lin He, Rui Wang, Yuezhu Wang, Jie Chen, Lijun Wang, Shuting Yu, Bi-Yun Wang, Jia Wei, Sichao Song, Xinyan Lu, Zhengchao Gao, Wen-Yi Gu, Xiao Deng, Dan Ma, Sen Wang, Wenhua Liang, Lei Fang, Caiping Cai, Xiefei Zhu, Baoliang Zhou, Z. Jeffrey Chen, Shuhua Xu, Yugao Zhang, Shengyue Wang, Tianzhen Zhang, Guoping Zhao, Xiao‐Ya Chen

Scientific Reports

DOI

2014

iBrick: A New Standard for Iterative Assembly of Biological Parts with Homing Endonucleases

Jia-Kun Liu, Wei-Hua Chen, Shuang-Xi Ren, Guo-Ping Zhao, Jin Wang

PLoS ONE

DOI

2014

EMSA analysis of ald promoter with purified His-tagged GlnR.

Ying Wang, Chen Li, Na Duan, Bin Li, Xiao-Ming Ding, Yu-Feng Yao, Jun Hu, Guo-Ping Zhao, Jin Wang

DOI

2014

Subdomain II of α-Isopropylmalate Synthase Is Essential for Activity

Zi-Long Zhang, Jian Wu, Wei Lin, Jin Wang, Han Yan, Wei Zhao, Jun Ma, Jianping Ding, Peng Zhang, Guo-Ping Zhao

Journal of Biological Chemistry

DOI

2014

Atypical OmpR/PhoB Subfamily Response Regulator GlnR of Actinomycetes Functions as a Homodimer, Stabilized by the Unphosphorylated Conserved Asp-focused Charge Interactions*

Wei Lin, Ying Wang, Xiaobiao Han, Zi-Long Zhang, Cheng-Yuan Wang, Jin Wang, Hua Yang, Yin-Hua Lu, Wei-Hong Jiang, Guo-Ping Zhao, Peng Zhang

Journal of Biological Chemistry

DOI

2014

GlnR Negatively Regulates the Transcription of the Alanine Dehydrogenase Encoding Gene ald in Amycolatopsis mediterranei U32 under Nitrogen Limited Conditions via Specific Binding to Its Major Transcription Initiation Site

Ying Wang, Chen Li, Na Duan, Bin Li, Xiao-Ling Ding, Yu-Feng Yao, Jun Hu, Guo-Ping Zhao, Jin Wang

PLoS ONE

DOI

2014

The First Complete Genome Sequence of the Class Fimbriimonadia in the Phylum Armatimonadetes

Ziye Hu, Yuezhu Wang, Wan‐Taek Im, Shengyue Wang, Guoping Zhao, Huajun Zheng, Zhe‐Xue Quan

PLoS ONE

DOI

2014

Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis

Li Xu, He Huang, Wei Wei, Yi Zhong, Biao Tang, Hua Yuan, Li Zhu, Weiyi Huang, Mei Ge, Shen Yang, Huajun Zheng, Weihong Jiang, Daijie Chen, Guoping Zhao, Wei Zhao

BMC Genomics

DOI

2014

Production of bioactive ginsenoside compound K in metabolically engineered yeast

Xing Yan, Yun Fan, Wei Wei, Pingping Wang, Qunfang Liu, Yongjun Wei, Lei Justan Zhang, Guoping Zhao, Jian‐Min Yue, Zhihua Zhou

Cell Research

DOI

2013

合成生物体将革新工业生物制造

丁陈君，陈云伟，陈方，赵国屏

《中国科学院院刊》，Vol. 28, No. 5

下载原文

2013

赵国屏 以科学思维看待“大师”现象

赵国屏，唐琳

《科学新闻》

2013

“人造生命”展现诱人前景

刘晓，王慧媛，王方，熊燕，赵国屏

《中国科学院院刊》，Vol. 28, No. 5

下载原文

2013

The MASTER (methylation-assisted tailorable ends rational) ligation method for seamless DNA assembly

Wei-Hua Chen, Zhong-Jun Qin, Jin Wang, Guo-Ping Zhao

Nucleic Acids Research

DOI

2013

Three of Four GlnR Binding Sites Are Essential for GlnR-Mediated Activation of Transcription of the Amycolatopsis mediterranei nas Operon

Ying Wang, Jing-Zhi Wang, Zhihui Shao, Hua Yuan, Yin-Hua Lu, Wei-Hong Jiang, Guo-Ping Zhao, Jin Wang

Journal of Bacteriology

DOI

2013

Genetic and molecular biological characterization of two homologous cheR genes from Leptospira interrogans.

Yun-Yi Zhang, Ke Dong, L. Zeng, Qing-Tian Li, Chang Liu, Jin Wang, Xiao-Kui Guo, Guo-Ping Zhao

Acta Biochimica et Biophysica Sinica

DOI

2013

Mycobacterial MazG Safeguards Genetic Stability via Housecleaning of 5-OH-dCTP

Liang-Dong Lyu, Bikui Tang, Xiao‐Yong Fan, Hui Ma, Guoping Zhao

PLoS Pathogens

DOI

2013

Control of Directionality in Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination

Lin Zhang, Binyan Zhu, Ruixue Dai, Guoping Zhao, Xiaoming Ding

PLoS ONE

DOI

2013

The genome of the hydatid tapeworm Echinococcus granulosus

Huajun Zheng, Wenbao Zhang, Liang Zhang, Zhuangzhi Zhang, Jun Li, Gang Lu, Yongqiang Zhu, Yuezhu Wang, Yin Huang, Jing Liu, Hui Kang, Jie Chen, Lijun Wang, Aojun Chen, Shuting Yu, Zhengchao Gao, Lei Jin, Wenyi Gu, Zhiqin Wang, Li Zhao, Baoxin Shi, Hao Wen, Renyong Lin, Malcolm K. Jones, Broňa Brejová, Tomáš Vinař, Guoping Zhao, Donald Peter McManus, Chen Zhu, Yan Zhou, Shengyue Wang

Nature Genetics

DOI

2013

Genome Sequencing and Analysis of BCG Vaccine Strains

Wen Zhang, Yuanyuan Zhang, Huajun Zheng, Yuanlong Pan, Haican Liu, Pengcheng Du, Li Wan, Jun Liu, Baoli Zhu, Guoping Zhao, Chen Chen, Kanglin Wan

PLoS ONE

DOI

2013

ContigScape: a Cytoscape plugin facilitating microbial genome gap closing

Biao Tang, Qi Wang, Minjun Yang, Feng Xie, Yongqiang Zhu, Ying Zhuo, Shengyue Wang, Hong Chao Gao, Xiaoming Ding, Lixin Zhang, Guoping Zhao, Huajun Zheng

BMC Genomics

DOI

2013

An Efficient Procedure for Marker-Free Mutagenesis of S. coelicolor by Site-Specific Recombination for Secondary Metabolite Overproduction

Bo Zhang, Lin Zhang, Ruixue Dai, Meiying Yu, Guoping Zhao, Xiaoming Ding

PLoS ONE

DOI

2012

合成生物学伦理、法律与社会问题探讨

刘晓，熊燕，王方，赵国屏

《生命科学》

2012

结核分枝杆菌基因组学与基因组进化

宛宝山，张秋芬，周爱萍，赵国屏，姚玉峰

《生物化学与生物物理进展》

2012

Characterization of a New GlnR Binding Box in the Promoter of amtB in Streptomyces coelicolor Inferred a PhoP/GlnR Competitive Binding Mechanism for Transcriptional Regulation of amtB

Ying Wang, Xu-Feng Cen, Guo-Ping Zhao, Jin Wang

Journal of Bacteriology

DOI

2012

Complete Genome Sequence of Amycolatopsis mediterranei S699 Based on De Novo Assembly via a Combinatorial Sequencing Strategy

Biao Tang, Wei Zhao, Huajun Zheng, Ying Zhuo, Lixin Zhang, Guoping Zhao

Journal of Bacteriology

DOI

2012

Characterization of acetyl-CoA and propionyl-CoA carboxylases encoded by Leptospira interrogans serovar Lai: an initial biochemical study for leptospiral gluconeogenesis via anaplerotic CO2 assimilation

Nanqiu Peng, Yi Zhong, Qing Zhang, Mingyue Zheng, Wei Zhao, Hualiang Jiang, Chen Yang, Xiaokui Guo, Guoping Zhao

Acta Biochimica et Biophysica Sinica

DOI

2011

合成生物学的科学内涵和社会意义——合成生物学专刊序言

赵国屏

《生命科学》

2011

合成生物学发展现状与前景

熊燕，陈大明，杨琛，赵国屏

《生命科学》

2011

Identification and functional analysis of a nitrate assimilation operon nasACKBDEF from Amycolatopsis mediterranei U32

Zhihui Shao, Jin Gao, Xiao-Ming Ding, Jin Wang, J. Chiao, Guo-Ping Zhao

Archives of Microbiology

DOI

2011

Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

W. Yue, Hai-Feng Wang, Liang-Dan Sun, Fu-Lei Tang, Zhongliang Liu, Hong-Xing Zhang, Wen-Qiang Li, Yan-Ling Zhang, Yang Zhang, Cui Ma, B. Du, Li-fang Wang, Yun-Qing Ren, Yong-Feng Yang, Xiao-Feng Hu, Yi Wang, W. Deng, Li-Wen Tan, Yun-Long Tan, Qi Chen, Guang-Ming Xu, Guigang Yang, X. Zuo, Hao Yan, Y. Ruan, Tian-Lan Lu, Xue Han, Xiaohong Ma, Yan Wang, L. Cai, Chao Jin, Hong-Yan Zhang, Jun Yan, Wei-Feng Mi, Xianyong Yin, Wenbin Ma, Qi Liu, Lan Kang, Wei Sun, Cheng-Ying Pan, Mei Shuang, Fu-De Yang, Chuan-Yue Wang, Jianli Yang, Ke-Qing Li, Xin Ma, Ling-Jiang Li, Xin Yu, Qi-Zhai Li, Xun Huang, L. Lv, Tao Li, Guo-Ping Zhao, Wei Huang, Xue-Jun Zhang, Dai Zhang

Nature Genetics

DOI

2011

Two genes, rif15 and rif16, of the rifamycin biosynthetic gene cluster in Amycolatopsis mediterranei likely encode a transketolase and a P450 monooxygenase, respectively, both essential for the conversion of rifamycin SV into B.

Hua Yuan, Wei Zhao, Yi Zhong, Jin Wang, Zhong-Jun Qin, Xiao-Ming Ding, Guo-Ping Zhao

Acta Biochimica et Biophysica Sinica

DOI

2011

Prokaryotic systematics in the genomics era

Xiao‐Yang Zhi, Wei Zhao, Wen‐Jun Li, Guoping Zhao

Antonie van Leeuwenhoek

DOI

2011

Tandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination

Lin Zhang, Guoping Zhao, Xiaoming Ding

Scientific Reports

DOI

2011

Complete Sequencing and Pan-Genomic Analysis of Lactobacillus delbrueckii subsp. bulgaricus Reveal Its Genetic Basis for Industrial Yogurt Production

Pei Hao, Huajun Zheng, Yao Yu, Guohui Ding, Wenyi Gu, Shuting Chen, Zhonghao Yu, Shuangxi Ren, Munehiro Oda, Tomonobu Konno, Shengyue Wang, Xuan Li, Zai-Si Ji, Guoping Zhao

PLoS ONE

DOI

2010

Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice

Chenhong Zhang, Menghui Zhang, Shengyue Wang, Ruijun Han, Youfang Cao, Weiying Hua, Yuejian Mao, Xiaojun Zhang, Xiaoyan Pang, Chaochun Wei, Guoping Zhao, Yan Chen, Liping Zhao

Isme Journal，Vol. 4, No. 2

DOI

2010

Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism

Wei Zhao, Yi Zhong, Hua Yuan, Jin Wang, Hua-Jun Zheng, Ying Wang, Xufeng Cen, Feng-Yi Xu, J. Bai, Xiaobiao Han, G. Lu, Yongqiang Zhu, Zhihui Shao, Han Yan, Chen Li, Nanqiu Peng, Zi-Long Zhang, Yun-Yi Zhang, Wei Lin, Yun-Liu Fan, Zhong-Jun Qin, Yongfei Hu, Baoli Zhu, Sheng-Yue Wang, Xiao-Ming Ding, Guo-Ping Zhao

Cell Research

DOI

2010

DNA Cleavage is Independent of Synapsis during Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination

Lin Zhang, Lu Wang, Jin Wang, Xijun Ou, Guoping Zhao, Xiaoming Ding

Journal of Molecular Cell Biology

DOI

2010

proTF: a comprehensive data and phylogenomics resource for prokaryotic transcription factors

Jie Bai, Junrong Wang, Feng Xue, Jingsong Li, Lijing Bu, Junming Hu, Gang Xu, Qiyu Bao, Guoping Zhao, Xiaoming Ding, Jie Yan, Jinyu Wu

Bioinformatics

DOI

2010

Mycobacterial MazG Is a Novel NTP Pyrophosphohydrolase Involved in Oxidative Stress Response

Liangdong Lu, Qing Sun, Xiao‐Yong Fan, Yi Zhong, Yufeng Yao, Guoping Zhao

Journal of Biological Chemistry

DOI

2010

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

Qijun Wang, Yakun Zhang, Chen Yang, Hui Xiong, Yan Lin, Jun Yao, Hong Li, Lu Xie, Wei Zhao, Yufeng Yao, Zhi-Bin Ning, Rong Zeng, Yue Xiong, Kun‐Liang Guan, Shimin Zhao, Guoping Zhao

Science

DOI

2009

Mapping Human Genetic Diversity in Asia

M. Abdulla, Ikhlak Ahmed, A. Assawamakin, J. Bhak, S. Brahmachari, G. Calacal, A. Chaurasia, Chien-Hsiun Chen, Jie-Ming Chen, Yuan-Tsong Chen, Jiayou Chu, E. C. Cutiongco-de la Paz, Maria Corazon Abogado De Ungria, F. Delfin, J. Edo, S. Fuchareon, H. Ghang, T. Gojobori, Junsong Han, Sheng-Feng Ho, B. Hoh, Wei Huang, H. Inoko, Pankaj K. Jha, T. Jinam, Li Jin, Jongsun Jung, D. Kangwanpong, Jatupol Kampuansai, G. Kennedy, Preeti Khurana, Hyung-Lae Kim, Kwang-joong Kim, Sangsoo Kim, Woo-Yeon Kim, K. Kimm, R. Kimura, T. Koike, S. Kulawonganunchai, Vikrant Kumar, P. Lai, Jong-Young Lee, Sunghoon Lee, Edison T. Liu, P. Majumder, Kiran Kumar Mandapati, S. Marzuki, Wayne Mitchell, M. Mukerji, K. Naritomi, C. Ngamphiw, N. Niikawa, N. Nishida, B. Oh, S. Oh, J. Ohashi, A. Oka, R. Ong, C. Padilla, P. Palittapongarnpim, Henry B. Perdigon, M. Phipps, E. Png, Y. Sakaki, Jazelyn M. Salvador, Yuliana Sandraling, V. Scaria, M. Seielstad, Mohd Sidek, Amit Sinha, M. Srikummool, H. Sudoyo, S. Sugano, H. Suryadi, Yoshiyuki Suzuki, K. Tabbada, Adrian K S Tan, K. Tokunaga, S. Tongsima, Lilian P Villamor, Eric Wang, Ying Wang, Hai-Feng Wang, Jer-yuarn Wu, Hua-sheng Xiao, Shu-Hua Xu, Jin Ok Yang, Y. Shugart, H. Yoo, W. Yuan, Guo-Ping Zhao, B. Zilfalil

Science

DOI

2009

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

Jian-Wen Han, Hou-Feng Zheng, Yong Cui, Liang-Dan Sun, D. Ye, Zhilin Hu, Jin-hua Xu, Zhi-Ming Cai, Wei Huang, Guo-Ping Zhao, Hong-Fu Xie, H. Fang, Qian-Jin Lu, Jian-hua Xu, Xiang-Pei Li, Yun-Feng Pan, D. Deng, F. Zeng, Zhi-zhong Ye, Xiao-Yan Zhang, Qing-Wen Wang, Fei Hao, Li Ma, X. Zuo, Fu-Sheng Zhou, Wen-Hui Du, Yi-lin Cheng, Jian-Qiang Yang, Song-Ke Shen, Jian Li, Y. Sheng, Xiaowei Zuo, Weidong Zhu, Fei Gao, Pei-Lian Zhang, Qing Guo, Bo Li, Min Gao, F. Xiao, C. Quan, Chi Zhang, Zheng Zhang, Kun-Ju Zhu, Yang Li, Da-Yan Hu, Wen-Sheng Lu, Jian-Lin Huang, Sheng-Xiu Liu, Hui Li, Yun-Qing Ren, Zai-Xing Wang, Chun-Jun Yang, Pei-Guang Wang, Wen Zhou, Yong-mei Lv, An-Sheng Zhang, Sheng-Quan Zhang, Da Lin, Yi Li, H. Low, M. Shen, Z. Zhai, Ying Wang, Fengyu Zhang, Sen Yang, Jian-jun Liu, Xue-Jun Zhang

Nature Genetics

DOI

2009

GlnR positively regulates nasA transcription in Streptomyces coelicolor.

Jin Wang, Guo-Ping Zhao

Biochemical and Biophysical Research Communications - BBRC

DOI

2009

Current research status of immunology in the genomic era

Hao-Wen Li, Jinzhi Li, Guo-Ping Zhao, Ying Wang

Science in China Series C Life Sciences

DOI

2009

Characterization ofrrdA, a TetR Family Protein Gene Involved in the Regulation of Secondary Metabolism inStreptomyces coelicolor

Xijun Ou, Bo Zhang, Lin Zhang, Guoping Zhao, Xiaoming Ding

Applied and Environmental Microbiology

DOI

2009

Structure modeling and spatial epitope analysis for HA protein of the novel H1N1 influenza virus

Di Jia Wu, Tianlei Xu, Jing Sun, Jianxin Dai, Guohui Ding, Yungang He, Zhengfeng Zhou, Hui Xiong, Hui Dong, Weirong Jin, Chao Bian, Jin Li, Hongyan Wang, Xiaoning Wang, Zhong Yang, Zhong Yang, Hao Wang, Xiaoyan Che, Zhong Xian Huang, Ke Lan, Bing Sun, Fan Wu, ZhenAn Yuan, Xi Zhang, Xiao‐Nong Zhou, Jiahai Zhou, Zhiyong Ma, Guangzhi Tong, Yajun Guo, Guoping Zhao, Yixue Li, Zhiwei Cao

Chinese Science Bulletin

DOI

2009

The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus

Yungang He, Guohui Ding, Chao Bian, Zhong Wei Huang, Ke Lan, Bing Sun, XueCai Wang, Yixue Li, Hongyan Wang, Xiaoning Wang, Zhong Yang, Zhong Yang, Weirong Jin, Hui Xiong, Jianxin Dai, Yajun Guo, Hao Wang, Xiaoyan Che, Fan Wu, ZhenAn Yuan, Xi Zhang, Zhiwei Cao, Xiao‐Nong Zhou, Jiahai Zhou, Zhiyong Ma, Guangzhi Tong, Guoping Zhao, Jin Li

Chinese Science Bulletin

DOI

2009

Subtyping of type A influenza by sequencing the variable regions of HA gene specifically amplified with RT-PCR

Yan An, Guohui Ding, Zhen-feng Zhou, Hui Dong, Yakun Zhang, Lei Zhu, Yungang He, Guoqing Zhang, Yixue Li, Bing Sun, Zhong Wei Huang, Ke Lan, Jin Li, Hongyan Wang, Xiaoning Wang, Zhong Yang, Zhong Yang, Jianxin Dai, Yajun Guo, Hao Wang, Xiaoyan Che, Fan Wu, Zhengan Yuan, Xi Zhang, Zhiwei Cao, Xiao‐Nong Zhou, Jiahai Zhou, Zhiyong Ma, Guangzhi Tong, Guoping Zhao, Weirong Jin, Hui Xiong

Chinese Science Bulletin

DOI

2009

Learn to fight from the war

Guoping Zhao, Yang Zhong

Chinese Science Bulletin

DOI

2008

A novel differential expression system for gene modulation in Mycobacteria

Xiao‐Yong Fan, Hui Ma, Jian Guo, Zhong-Ming Li, Zhiheng Cheng, Sheng-Qi Guo, Guoping Zhao

Plasmid

DOI

2008

SarA influences the sporulation and secondary metabolism in Streptomyces coelicolor M145

Xijun Ou, Bo Zhang, Lin Zhang, Kai Dong, Chun Liu, Guoping Zhao, Xiaoming Ding

Acta Biochimica et Biophysica Sinica

DOI

2008

Highly Efficient In Vitro Site-Specific Recombination System Based on Streptomyces Phage φBT1 Integrase

Lin Zhang, Xijun Ou, Guoping Zhao, Xiaoming Ding

Journal of Bacteriology

DOI

2008

Genetic Basis of Virulence Attenuation Revealed by Comparative Genomic Analysis of Mycobacterium tuberculosis Strain H37Ra versus H37Rv

Huajun Zheng, Liangdong Lu, Bofei Wang, Shiying Pu, Xianglin Zhang, Genfeng Zhu, Wanliang Shi, Lu Zhang, Honghai Wang, Shengyue Wang, Guoping Zhao, Ying Zhang

PLoS ONE

DOI

2008

Genome Biology of Actinobacillus pleuropneumoniae JL03, an Isolate of Serotype 3 Prevalent in China

Zhuofei Xu, Yan Zhou, Liangjun Li, Rui Zhou, Shaobo Xiao, Yun Wan, Sihua Zhang, Kai Wang, Wei Li, Lu Li, Hui Jin, Mingsong Kang, Baolige Dalai, Tingting Li, Lei Liu, Yangyi Cheng, Lei Zhang, Tao Xu, Huajun Zheng, Shiying Pu, Bofei Wang, Wenyi Gu, Xianglin Zhang, Geng-Feng Zhu, Shengyue Wang, Guoping Zhao, Huanchun Chen

PLoS ONE

DOI

2007

Evolutionary Relationships between Bat Coronaviruses and Their Hosts

Jie Cui, Naijian Han, Daniel G. Streicker, Gang Li, Xianchun Tang, Zhengli Shi, Zhìhóng Hú, Guoping Zhao, Arnaud L Fontanet, Yi Guan, Lin‐Fa Wang, Gareth Jones, Hume Ernest Field, Peter Daszak, Shuyi Y. Zhang

Emerging infectious diseases

DOI

2007

A complex role of Amycolatopsis mediterranei GlnR in nitrogen metabolism and related antibiotics production

Hao Yu, Yufeng Yao, Yang Liu, Jiao Ruishen, Weihong Jiang, Guoping Zhao

Archives of Microbiology

DOI

2007

A comprehensive survey on isoleucine biosynthesis pathways in seven epidemicLeptospira interrogansreference strains of China

Ying Ning Zou, Xiaokui Guo, Mathieu Picardeau, Hai Xu, Guoping Zhao

FEMS Microbiology Letters

DOI

2006

体内重组工程:功能基因组研究中的一种新武器

田永强，赵国屏，覃重军

《中国抗生素杂志》

2006

Bacterial type I glutamine synthetase of the rifamycin SV producing actinomycete, Amycolatopsis mediterranei U32, is the only enzyme responsible for glutamine synthesis under physiological conditions.

W. Peng, Jin Wang, Ting Wu, Jian-Qiang Huang, J. Chiao, Guo-Ping Zhao

Acta Biochimica et Biophysica Sinica

DOI

2006

Identification and Characterization of glnA Promoter and its Corresponding Trans-regulatory Protein GlnR in the Rifamycin SV Producing Actinomycete, Amycolatopsis mediterranei U32

Hao Yu, Wentao Peng, Yang Liu, Ting Wu, Yufeng Yao, Ming-Xue Cui, Weihong Jiang, Guoping Zhao

Acta Biochimica et Biophysica Sinica

DOI

2005

Simple sequence repeat-based consensus linkage map of Bombyx mori.

X. Miao, S. Xub, Ming-hui Li, Mu-Wang Li, Jian-Hua Huang, F. Dai, Susan Marino, D. R. Mills, Peiyu Zeng, K. Mita, Shi-Hai Jia, Yong Zhang, Wen-Bin Liu, Hui Xiang, Qiu-Hong Guo, Anying Xu, Xiang-yin Kong, Hong-Xuan Lin, Yao-Zhou Shi, Gang Lu, Xiang-Lin Zhang, Wei Huang, Y. Yasukochi, T. Sugasaki, T. Shimada, J. Nagaraju, Zhonghuai Xiang, Sheng-Yue Wang, M. Goldsmith, Cheng Lu, Guo-Ping Zhao, Yong-Ping Huang

Proceedings of the National Academy of Sciences of the United States of America

DOI

2005

Identification of Two Critical Amino Acid Residues of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Its Variation in Zoonotic Tropism Transition via a Double Substitution Strategy

Xiuxia Qu, Pei Hao, Xijun Song, Siming Jiang, Yanxia Liu, Peigang Wang, Xi Rao, Huai‐Dong Song, Shengyue Wang, Yu Zuo, Aihua Zheng, Min Luo, Huálín Wáng, Fēi Dèng, Hanzhong Wang, Zhìhóng Hú, Mingxiao Ding, Guoping Zhao, Hongkui Deng

Journal of Biological Chemistry

DOI

2003

重组SARS冠状病毒刺突蛋白的表达和分离纯化

俞浩，杨勇，张伟，谢幼华，秦峻，汪垣，郑华宝，赵国屏，杨晟，姜卫红

Acta Biochimica et Biophysica Sinica

2003

用生物信息学的方法预测SARS病毒的基因组包装信号序列(英文)

秦磊，熊斌，罗成，郭宗明，郝沛，苏炅，南蓬，冯颖，石忆湘，俞晓晶，罗小民，陈凯先，沈旭，沈建华，左建平，赵国屏，石铁流，何伟忠，钟扬，蒋华良，李亦学

Acta Pharmacologica Sinica

2003

Divergence of the genes on human chromosome 21 between human and other hominoids and variation of substitution rates among transcription units

Jinxiu Shi, Hui-Feng Xi, Ying Wang, Chenghui Zhang, Zheng-Wen Jiang, Kuixing Zhang, Yayun Shen, Lin Jin, Kai-Yue Zhang, W. Yuan, Jie Lin, Qi Hua, Fengqing Wang, Shu-Hua Xu, S. Ren, Shi-Jie Xu, Guo-Ping Zhao, Zhu Chen, Li Jin, Wei Huang

Proceedings of the National Academy of Sciences of the United States of America

DOI

2003

A high-resolution genetic and physical map of a mouse coat abnormality locus (Uncv).

Yao-Zhou Shi, Dong-Ping Wang, Lan-Dian Hu, Guo-Ping Zhao, Yu-zhen Wang, Xiang-yin Kong, Shan-Ru Li

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

2002

生物信息学

赵国屏

《科学出版社》

1998

基因组及后基因组时代的微生物学

赵国屏

《生命科学》

会议论文

2016

UDP-糖基转移酶的鉴定及代谢工程改造酿酒酵母合成稀有人参皂苷

王平平，魏维，魏勇军，杨成帅，赵国屏，严兴，周志华

《中国菌物学会2016年学术年会》

2016

人参皂苷合成关键糖基转移酶基因鉴定及代谢工程改造酿酒酵母合成稀有人参皂苷

王平平，魏维，魏勇军，杨成帅，赵国屏，岳建民，严兴，周志华

《第九届中国模式真菌研讨会》

2014

病原微生物基因组学研究:为防御传染病提供新策略

赵国屏

《纪念中国微生物学会临床微生物学专业委员会成立五周年-第五届中国临床微生物学大会暨台湾海峡两岸微生物学与免疫学论坛论文汇编》

2014

在酿酒酵母底盘细胞中利用单糖合成稀有人参皂苷Compound K

严兴，范云，魏维，王平平，刘群芳，魏勇军，张磊，赵国屏，岳建民，周志华

《中国菌物学会第六届会员代表大会（2014年学术年会）暨贵州省食用菌产业发展高峰论坛》

2014

Pathogen Genomics:Revolutionizing the Regiment against Infectious Diseases

赵国屏

《中国首届One Health研究国际论坛》

2014

基因组科学与健康

赵国屏

《2014第八届中国生物产业大会基因科学与人类健康产业发展论坛》

2014

New Insights into Pathogenic Leptospira Interrogans Genomic Constitution and Genetic Transformation Systems Establishment

朱威南，王金，朱泳璋，唐标，张云怡，何平，张彦，刘伯玉，秦金红，赵国屏，郭晓奎

《中华医学会2014全国微生物学与免疫学学术年会论文汇编》

2012

ConitgScape:微生物基因组Gap Closing工具

唐标，王琪，杨敏俊，谢峰，卓英，王升跃，张立新，赵国屏，郑华军

《第四届全国微生物基因组学学术研讨会论文集》

2012

利用比较基因组学解析工业菌株中阿维菌素的高产机制

卓英，王琪，谢峰，陈金松，贾晓鹏，唐标，白超炫，高弘，刘梅，郑华军，孙际宾，赵国屏，张立新

《第四届全国微生物基因组学学术研讨会论文集》

2010

中国微生物基因组研究:回顾与展望

赵国屏

《2010年第四届全国微生物遗传学学术研讨会》

2008

胸膜肺炎放线杆菌JL03株基因组测序与比较基因组学分析

徐卓菲，周锐，黎璐，李良军，万云，肖少波，周雁，王升跃，赵国屏，陈焕春

《中国微生物学会《第二届全国农业微生物研究及产业化研讨会》和《第十一届全国杀虫微生物学术研讨会》暨《湖北省暨武汉市微生物学会和内蒙古微生物学会2008年会》》

2006

总结基因组研究成果,发展微生物系统生物学

赵国屏

《2006中国微生物学会第九次全国会员代表大会暨学术年会》

2006

钩体中异亮氨酸合成途径与其进化地位有关

邹膺，郭晓奎，赵国屏

《第二届中国青年学者微生物遗传学学术研讨会》

2006

基于生物信息学和基因芯片的钩端螺旋体疫苗候选基因的初步筛选

杨宏亮，朱泳璋，秦金红，何平，赵国屏，郭晓奎

《上海市预防医学会第二届学术年会》

2006

问号钩端螺旋体的比较基因组学研究

何平，盛跃颖，史耀舟，蒋秀高，秦金红，张志明，杨杨，赵国屏，郭晓奎

《上海市预防医学会第二届学术年会论文汇编》

2006

问号钩端螺旋体α-异丙基苹果酸合成酶与柠草酸合成酶底物专一性比较

马骏，张鹏，丁建平，赵国屏

《第二届中国青年学者微生物遗传学学术研讨会》

2002

钩端螺旋体2-甲基苹果酸(Citramalate)合成酶的克隆、表达及功能分析

徐海，张玉臻，任双喜，缪有刚，郭晓奎，张怡轩，胡宝瑜，姜卫红，赵国屏

《首届中国青年学者微生物遗传学学术研讨会论文摘要集》

预印本

2023

Mycobacterial DnaQ is an Alternative Proofreader Ensuring DNA Replication Fidelity

Ming-Zhi Deng, Qingyun Liu, Shu-Jun Cui, Han Fu, Mingyu Gan, Yuanyuan Xu, Xia Cai, Wei Sha, Guoping Zhao, Sarah M. Fortune, Liang-Dong Lyu

bioRxiv (Cold Spring Harbor Laboratory)

DOI

2005

Comparative and functional genomic analyses of the pathogenicity of phytopathogenXanthomonas campestrispv.campestris

Wei Qian, Yantao Jia, Shuangxi Ren, Yong-Qiang He, Jia‐Xun Feng, Ling-Feng Lu, Qi‐Hong Sun, Ge Ying, Dong‐Jie Tang, Hua Tang, Wei Wu, Pei Hao, Lifeng Wang, Bo‐Le Jiang, Shen-yan Zeng, Wen-Yi Gu, Gang Lü, Rong Li, Yingchuan Tian, Zhijian Yao, Gang Fu, Baoshan Chen, Rongxiang Fang, Boqin Qiang, Zhu Chen, Guoping Zhao, Ji‐Liang Tang, Chaozu He

Genome Research

DOI

研究方向

微生物基因组学与进化基因组学系统与合成生物学肠道微生物组及蛋白质乙酰化酵母染色体重构与天然产物细胞工厂

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