丁强｜清华大学｜学者主页

2026

腋窝入路单孔腔镜电剪刀法乳房皮下腺体切除技术要点

周文斌，王丹丹，潘红，石靓，夏添松，梁燕，马丹丹，王水，齐晓伟，丁强

《中国普通外科杂志》

2026

血管内介入栓塞治疗腹部手术后胃肠瘘并发出血

丁强，丁锦辉，顾国胜，付大鹏，王胜军，彭伟

《中国微创外科杂志》

2026

SARS‐CoV‐2 enhances lysosomal exocytosis and deacidifies lysosomes to facilitate viral release

Fu-Jun Qin, Chuang Yan, Zi-Zheng Liu, Dian-Bing Wang, H. Zhong, Qiang Ding, Ming-Hai Chen, Xian-En Zhang

mLife

DOI

2026

Real-time tracking of dual-labeled fluorescent SARS-CoV-2 reveals that the nucleocapsid mutations R203K/G204R accelerate viral uncoating

Zi-Zheng Liu, Ji-Bin Zhang, Qiang Ding, Chen-Yang Yang, Han Wu, Shi-Min Li, Fu-Jun Qin, Xian-En Zhang, Dian-Bing Wang

Journal of Virology

DOI

2026

EIF4H and YBX1 are essential host factors for hepatitis E virus replication and pathogenesis

Xiaohui Ju, Lin Dong, Tianxu Liu, Fan Zhang, Xuege Sun, Michael P. Schwoerer, Wenlin Ren, Mingli Gong, Alexander Ploß, Wei Qin, Xianfang Wu, Lin Wang, Qiang Ding

Proceedings of the National Academy of Sciences

DOI

2025

Vesicle-associated membrane protein 5 is an intrinsic defense factor for embryonic stem cells against coronaviruses

Hui-Jun Dong, Zi-Hang Pan, Peng-Tao Jiao, F. Ye, Qi Peng, Yanying Yu, Xin-Yuan Lai, Huan Li, Zhao Guan, Juan Deng, Tao Shen, Wen-Jie Tan, Yi Shi, Qiang Ding, Jian-Yuan Luo, Tong Li, H. Zhuang, Kuan-Hui Xiang

Nature Communications

DOI

2025

Interferon-stimulated gene GALNT2 restricts respiratory virus infections

Wei Ran, Jinghong Yang, Shi Yu, Qingtao Hu, Yuqi He, Sheng-Jun Wang, Chun-Xiao Wei, Jing Sun, Ai-Ru Zhu, Fang Li, Lu Zhang, Peng-Fei Li, Huina Hu, Ruan-Gang Pan, Yanying Yu, Yanqiu Yuan, Ling Sun, Yan-Qun Wang, Zhao-Yong Zhang, Zhao Chen, Dong-Lan Liu, Qi-Hong Yan, Dong Wang, Kuai Yu, Yi-Liang Wang, Jianfen Zhuo, Z. Zhuang, Hua Tao, Qiuhui Zeng, Kai-Xin Zhou, Fenghua Chen, Wen-Wen Tang, Yu-Zheng Zhou, Rong Bai, Yong-Hao Xu, Na Li, Jun Dai, Hongyu Zhao, Jung-Eun Park, Tao Wang, Qiang Ding, S. Perlman, Jing-Xian Zhao, Yang Mao, Shao-Bo Wang, Jin-Cun Zhao

Nature Microbiology

DOI

2025

The prion-like characteristic of ORF3 contributes to virion release and pathogenesis of hepatitis E virus

Ya-Jing Wang, Houlu Tian, Na Shi, Chun-Yan Wu, Yao-Wei Huang, Yong-Lin Yang, Qiang Ding, Xu Zheng, Qin Zhao, Zhao-Nong Hu, Jiao-Jiao Luo, Le-Le Feng, Lingdong Xu, M. Tuite, Hongying Chen, Yu-Chen Nan

Proceedings of the National Academy of Sciences of the United States of America

DOI

2025

The R203M and D377Y mutations of the nucleocapsid protein promote SARS-CoV-2 infectivity by impairing RIG-I-mediated antiviral signaling

Yongkui Li, Moran Li, Heng Xiao, Feng Liao, Miaomiao Shen, Wei-Wei Ge, Junxian Ou, Yuqing Liu, Lu-Miao Chen, Yue Zhao, Pin Wan, Jinbiao Liu, Jun Chen, Xian-Wu Lan, Shaorong Wu, Qiang Ding, Geng Li, Qiwei Zhang, Pan Pan

PLoS Pathogens

DOI

2025

UHRF1 restricts HCoV-229E infection through epigenetic silencing of the viral receptor APN

Peng-Cheng Wang, Zi-Qiao Wang, Fei Feng, Lisha Yin, Yuyuan Zhang, Zhichao Gao, Jiannan Chen, Ping Zhang, Shui-Qiao Yuan, Qiang Ding, Yue Hong, Yuanlin Song, Chun Li, Jin-Cun Zhao, Rong Zhang

bioRxiv

DOI

2025

DAZAP2 functions as a pan-coronavirus restriction factor by inhibiting viral entry and genomic replication

Fei Feng, Jiannan Chen, Rong Li, Yun-Kai Zhu, Yanlong Ma, Zi-Qiao Wang, Yuyan Wang, Zhichao Gao, Lulu Yang, Ying Yu, Yanfeng Liu, Ying-Jie Sun, Ying Liao, Xin-Xin Huang, Qisheng Zhang, Yongheng Huang, Lin Qiu, Jia-Yu Wu, Jing-Xian Zhao, Chao Liu, Qiang Ding, Youhua Xie, Zheng-Hong Yuan, Yue Hong, Ping Zhang, Jing Sun, Jin-Cun Zhao, Rong Zhang

bioRxiv

DOI

2025

Glycosylphosphatidylinositol biosynthesis functions as a conserved host defense pathway against coronaviruses via regulation of LY6E

Yanlong Ma, Fei Feng, Hui Feng, Xue Ma, Zi-Qiao Wang, Yutong Han, Yun-Kai Zhu, Yu-Yan Wang, Zhichao Gao, Yuyuan Zhang, Qiang Ding, Jin-Cun Zhao, Rong Zhang

PLoS Pathogens

DOI

2025

Structural basis of DNA replication fidelity of the Mpox virus

Yufeng Xie, Lu Kuai, Qi Peng, Qian Wang, Han Wang, Xiaomei Li, J. Qi, Qiang Ding, Yi Shi, G. Gao

Proceedings of the National Academy of Sciences of the United States of America

DOI

2025

Enantiomer-dependent and modification-free DNA matrix as an adjuvant for subunit vaccines against SARS-CoV-2 or pneumococcal infections

Cuifeng Li, Yuxin Li, Bini Zhou, Tong Li, Xiaohui Wei, Kun Chen, Wenlong Chen, Ziwei Shi, Xiaobin Dai, Jiachen Zhang, Yang Chen, Zhenglin Ji, Wenbo Sun, Ji Gao, Jing Wu, Bin-Bin Zhao, Xin Min, Yujie Li, Lin Lin, Wei Yang, Min Wang, Zezhong Liu, Yaping Liu, Chenyou Zhu, Bo Kyung Yang, Jiang‐Fei Xu, Li‐Tang Yan, Yi Shi, Lu Lu, Linqi Zhang, Qiang Ding, Jing Xue, Baidong Hou, Hai Qi, Jiangning Liu, Yuhe Renee Yang, Dongsheng Liu, Wanli Liu

Nature Biomedical Engineering

DOI

2025

Design, synthesis and biological evaluation of dapsone derivatives with broad-spectrum antiviral activity

Ren‐Jie Lin, Jiajia Han, Yun He, Lin Xie, Tianyu Gao, Yaoming Chen, Yaoming Chen, Ye Zhong, Qiang Ding, Kui Cheng, Xingang Yao, Zhipeng Chen

European Journal of Medicinal Chemistry

DOI

2024

TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry

Yifan Xie, Jie Cao, Shuyi Gan, Lingdong Xu, Dongjie Zhang, Suhong Qian, Feng Xu, Qiang Ding, J. Schoggins, Wenchun Fan

PLoS Pathogens

DOI

2024

Zika virus NS5 protein inhibits type I interferon signaling via CRL3 E3 ubiquitin ligase-mediated degradation of STAT2

Wenlin Ren, Chong-Lei Fu, Yu Zhang, Xiaohui Ju, Xi Jiang, Jing-Wei Song, M. Gong, Zhuoyang Li, Wenchun Fan, Jun Yao, Qiang Ding

Proceedings of the National Academy of Sciences of the United States of America

DOI

2024

Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection

M. Gong, Cheng Peng, Chen Yang, Zhenhua Wang, Hong-Wu Qian, Xue Hu, Peng Zhou, Shan Chao, Qiang Ding

PLoS Pathogens

DOI

2024

Viral N protein hijacks deaminase-containing RNA granules to enhance SARS-CoV-2 mutagenesis

Zhean Li, Lingling Luo, Xiaohui Ju, Shisheng Huang, Liqun Lei, Yanying Yu, Jia Liu, Pumin Zhang, Tian H. Chi, Peixiang Ma, Cheng Huang, Xingxu Huang, Qiang Ding, Yu Zhang

The EMBO Journal

DOI

2024

Chemical Recording of Pump‐Specific Drug Efflux in Living Cells

Xuege Sun, Ying Chen, Yang Chen, Song Yang, Wei Lin, Baiyi Quan, Xuanzhen Pan, Qiang Ding, Xing Chen, Chu Wang, Wei Qin

Angewandte Chemie

DOI

2024

Receptor binding mechanism and immune evasion capacity of SARS-CoV-2 BQ.1.1 lineage

Chenghai Wang, Yu Zhang, Chen Guang Yang, Wenlin Ren, Chenguang Qiu, Shilong Fan, Qiang Ding, Jun Lan

Virology

DOI

2024

Drupacine as a potent SARS-CoV-2 replication inhibitor in vitro

Chen Yang, Yanying Yu, Qi Peng, Jingwei Song, Bo Sun, Yi Shi, Qiang Ding

Biosafety and Health

DOI

2024

Structural insights into the Langya virus attachment glycoprotein

Chenghai Wang, Min Li, Yufan Wang, Qiang Ding, Shilong Fan, Jun Lan

Structure

DOI

2024

Natural evidence of coronaviral 2′-O-methyltransferase activity affecting viral pathogenesis via improved substrate RNA binding

Jikai Deng, Shimin Yang, Yingjian Li, Xue Tan, Jiejie Liu, Yanying Yu, Qiang Ding, Chengpeng Fan, Hongyun Wang, Xianyin Chen, Qianyun Liu, Xiao Fang Guo, Feiyu Gong, Li Zhou, Yu Zheng Chen

Signal Transduction and Targeted Therapy

DOI

2024

Establishment of replication-competent vesicular stomatitis virus recapitulating SADS-CoV entry

Zihui Zhu, Yutong Han, Mingli Gong, Bo Sun, Rong Zhang, Qiang Ding

Journal of Virology

DOI

2024

A Comparative Study of Human Pluripotent Stem Cell-Derived Macrophages in Modeling Viral Infections

Yaxuan Zhang, Hui Qiu, Fuyu Duan, Haoran An, Huimin Qiao, Xingwu Zhang, Jing‐Ren Zhang, Qiang Ding, Jie Na

Viruses

DOI

2024

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

Zemin Yang, Bryan A. Johnson, Victoria Meliopoulos, Xiaohui Ju, Peipei Zhang, Michael P. Hughes, Jinjun Wu, Kaitlin P. Koreski, Jemma E. Clary, Ti‐Cheng Chang, Gang Wu, Jeff Hixon, Jay L. Duffner, Kathy Tin Kam Wong, Rene Lemieux, Kumari G. Lokugamage, R. Elias Alvarado, Patricia A. Crocquet-Valdes, David Hughes Walker, Kenneth S. Plante, Jessica A. Plante, Scott C. Weaver, Hong Joo Kim, Rachel E. Meyers, Stacey Schultz‐Cherry, Qiang Ding, Vineet D. Menachery, J. Paul Taylor

Cell Reports

DOI

2024

Recapitulation of the Powassan virus life cycle in cell culture

Jingwei Song, Jia-Yao Hong, Chen Yang, Yu Zhang, Zhuoyang Li, P. F. He, Qiang Ding

mBio

DOI

2024

Modeling antiviral response in the liver using human pluripotent stem cell-derived macrophages

Yaxuan Zhang, Xingwu Zhang, Fuyu Duan, Huimin Qiao, Mingli Gong, Hui Qiu, Xia Chen, Peiliang Wang, Yuan He, Qiang Ding, Jie Na

Life Medicine

DOI

2023

Evolution of SARS-CoV-2 Spikes shapes their binding affinities to animal ACE2 orthologs

Weitong Yao, Yujun Li, Danting Ma, Xu-Dong Hou, Haimin Wang, Xiaojuan Tang, Dechun Cheng, He Zhang, Chengzhi Du, Hong Pan, Chao Li, Hua Lin, Mengsi Sun, Qiang Ding, Yingjie Wang, Jiali Gao, Guocai Zhong

Microbiology Spectrum

DOI

2023

Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling

Xudong Chen, Min Xie, Sensen Zhang, Marta Tortajada, Jian Yin, Chang Liu, Youqi Zhang, Maeva Delacrétaz, Mingyue Song, Yixue Wang, Dong Lin, Qiang Ding, Boda Zhou, Xiaolin Tian, Haiteng Deng, Lina Xu, Xiaohui Liu, Zi F. Yang, Qing Chang, Jie Na, Wenwen Zeng, Giulio Superti‐Furga, Manuele Rebsamen, Maojun Yang

Nature Communications

DOI

2023

The PRMT5/WDR77 complex restricts hepatitis E virus replication

Xiaohui Ju, Yanying Yu, Wenlin Ren, Lin Dong, Xianbin Meng, Haiteng Deng, Yuchen Nan, Qiang Ding

PLoS Pathogens

DOI

2023

A tissue specific-infection mouse model of SARS-CoV-2

Bo Yeun Yang, Chao Liu, Xiaohui Ju, Bingbing Wu, Zhuangfei Wang, Fucheng Dong, Yanying Yu, Xiaohui Hou, Min Fang, Fei Gao, Xuejiang Guo, Yaoting Gui, Qiang Ding, Wei Li

Cell Discovery

DOI

2023

Evolution of Immune Evasion and Host Range Expansion by the SARS-CoV-2 B.1.1.529 (Omicron) Variant

Wenlin Ren, Yu Zhang, Juhong Rao, Ziyi Wang, Jun Lan, Kunpeng Liu, Xuekai Zhang, Xue Hu, Chen Yang, Guocai Zhong, Rong Zhang, Xinquan Wang, Chao Shan, Qiang Ding

mBio

DOI

2023

SARS‐CoV‐2 NSP8 suppresses type I and III IFN responses by modulating the RIG‐I/MDA5, TRIF, and STING signaling pathways

Jian Deng, Shengnan Zheng, Yang Xiao, Mei‐Ling Nan, Jing Zhang, Lulu Han, Yi Zheng, Yanying Yu, Qiang Ding, Chengjiang Gao, Pei‐Hui Wang

Journal of Medical Virology

DOI

2023

Vitamin C promotes ACE2 degradation and protects against SARS‐CoV‐2 infection

Yibo Zuo, Zhijin Zheng, Yingkang Huang, Jiuyi He, Lichao Zang, Tengfei Ren, Xinhua Cao, Ying Miao, Yukang Yuan, Yanli Liu, Feng Ma, Jianfeng Dai, Sheng Tian, Qiang Ding, Hui Zheng

EMBO Reports

DOI

2023

Design and characterization of novel SARS-CoV-2 fusion inhibitors with N-terminally extended HR2 peptides

Yue Hu, Yuanmei Zhu, Yanying Yu, Nian Liu, Xiaohui Ju, Qiang Ding, Yuxian He

Antiviral Research

DOI

2023

A vaccine delivery system promotes strong immune responses against SARS‐CoV‐2 variants

Zhiwei Lei, Leqing Zhu, Pan Pan, Zhihui Ruan, Yu Gu, Xichun Xia, Shengli Wang, Weiwei Ge, Yangrong Yao, Fazeng Luo, Heng Xiao, Jun Guo, Qiang Ding, Zhinan Yin, Yongkui Li, Zhen Luo, Qiwei Zhang, Xin Chen, Jianguo Wu

Journal of Medical Virology

DOI

2022

A preliminary study of comprehensive behavioral intervention for tics in Chinese children with chronic tic disorder or Tourette syndrome

Wen Xu, Qiang Ding, Ying Zhao, Wenqing Jiang, Jingjing Han, Jinhua Sun

Frontiers In Psychiatry，Vol. 13

DOI

2022

Characterization and analysis of linear epitopes corresponding to SARS‐CoV‐2 outbreak in Jilin Province, China

Wenying Gao, Zhaolong Li, Qingtian Guan, Wenzhe Cui, Baishong Zheng, Qiang Ding, Guoyue Lv, Jiancheng Xu, Wenyan Zhang

Journal of Medical Virology

DOI

2022

A CRISPR activation screen identifies genes that enhance SARS-CoV-2 infection

Fei Feng, Yunkai Zhu, Yanlong Ma, Yuyan Wang, Yu Yin, Xinran Sun, Yuanlin Song, Zhugui Shao, Xinxin Huang, Ying Liao, Jingyun Ma, Yuping He, Mingyuan Wang, Longhai Tang, Yao‐Wei Huang, Jincun Zhao, Qiang Ding, Youhua Xie, Qiliang Cai, Hui Xiao, Chun Li, Zhenghong Yuan, Rong Zhang

Protein & Cell

DOI

2022

Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2

Jun Lan, Peng Chen, Weiming Liu, Wenlin Ren, Linqi Zhang, Qiang Ding, Qi Zhang, Xinquan Wang, Jiwan Ge

Structure

DOI

2022

SARS-CoV-2 Omicron Variants Reduce Antibody Neutralization and Acquire Usage of Mouse ACE2

Ruoke Wang, Qi Zhang, Rui Zhang, Zhen Qin Aw, Peng Chen, Yi Hao Wong, Junxian Hong, Bin Ju, Xuanling Shi, Qiang Ding, Zheng Zhang, Justin Jang Hann Chu, Linqi Zhang

Frontiers in Immunology

DOI

2022

The Deubiquitinase USP29 Promotes SARS-CoV-2 Virulence by Preventing Proteasome Degradation of ORF9b

Wenying Gao, Liuli Wang, Xiaohui Ju, Simin Zhao, Zhaolong Li, Manman Su, Jiancheng Xu, Pei‐Hui Wang, Qiang Ding, Guoyue Lv, Wenyan Zhang

mBio

DOI

2022

Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication

Xinyuan Lai, Yanying Yu, Wei Xian, Fei Ye, Xiaohui Ju, Yuqian Luo, Huijun Dong, Yi‐Hua Zhou, Wenjie Tan, Hui Zhuang, Tong Li, Xiaoyun Liu, Qiang Ding, Kuanhui Xiang

iScience

DOI

2022

Characterization of SARS-CoV-2 Variants B.1.617.1 (Kappa), B.1.617.2 (Delta), and B.1.618 by Cell Entry and Immune Evasion

Wenlin Ren, Xiaohui Ju, Mingli Gong, Jun Lan, Yanying Yu, Quanxin Long, Devin Kenney, Aoife Kateri O’Connell, Yu Long Zhang, Jin Zhong, Guocai Zhong, Florian Douam, Xinquan Wang, Ailong Huang, Rong Zhang, Qiang Ding

mBio

DOI

2022

An ultrapotent RBD-targeted biparatopic nanobody neutralizes broad SARS-CoV-2 variants

Xiaojing Chi, Xinhui Zhang, Shengnan Pan, Yanying Yu, Yujin Shi, Tianli Lin, Huarui Duan, Xiuying Liu, Wenfang Chen, Xuehua Yang, Lan Chen, Xiaoqian Dong, Lili Ren, Qiang Ding, Jianwei Wang, Wei Zhong Yang

Signal Transduction and Targeted Therapy

DOI

2022

Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2

Shuyuan Zhang, Qingtai Liang, Xinheng He, Chongchong Zhao, Wenlin Ren, Ziqing Yang, Ziyi Wang, Qiang Ding, Haiteng Deng, Tong Wang, Linqi Zhang, Xinquan Wang

Cell Research

DOI

2022

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.

Wenlin Ren, Yunkai Zhu, Jun Lan, Hedi Chen, Yuyan Wang, Hongyang Shi, Fan Feng, D. W. Chen, Brianna J. Close, Xiaomin Zhao, Jianping Wu, Boxue Tian, Zhenghong Yuan, Dongming Zhou, Mohsan Saeed, Xinquan Wang, Rong Zhang, Qiang Ding

PubMed

DOI

2021

输尿管软镜钬激光碎石技术治疗CT值≥1200 HU肾结石的碎石方式选择

吴忠，高鹏，王路加，张元芳，丁强

《中国激光医学杂志》

2021

输尿管软镜联合钬激光技术治疗肾盏憩室内结石

吴忠，高鹏，王路加，丁强

《中国激光医学杂志》

2021

上海市泌尿外科会诊咨询服务部成立35周年纪念

张元芳，闵志廉，黄翼然，夏术阶，丁强，齐隽，周任远

《上海医学》

DOI

2021

Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption

Wenlin Ren, Jun Lan, Xiaohui Ju, Mingli Gong, Quanxin Long, Zihui Zhu, Yanying Yu, Jianping Wu, Jin Zhong, Rong Zhang, Shilong Fan, Guocai Zhong, Ailong Huang, Xinquan Wang, Qiang Ding

PLoS Pathogens

DOI

2021

Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2

Shaojun Zhang, Wenze Huang, Lili Ren, Xiaohui Ju, Mingli Gong, Jian Yu Rao, Lei Sun, Pan Li, Qiang Ding, Jianwei Wang, Qiangfeng Cliff Zhang

Cell Research

DOI

2021

Molecular determinants for regulation of G3BP1/2 phase separation by the SARS-CoV-2 nucleocapsid protein

Wenjie Huang, Xiaohui Ju, Min Tian, Xiaoyu Li, Yanying Yu, Qingxiang Sun, Qiang Ding, Da Jia

Cell Discovery

DOI

2021

Genome-wide transcriptomic analysis of highly virulent African swine fever virus infection reveals complex and unique virus host interaction

Xiaohui Ju, Fang Li, Jingrui Li, Chunyan Wu, Guangtao Xiang, Xiaomin Zhao, Yuchen Nan, Dongming Zhao, Qiang Ding

Veterinary Microbiology

DOI

2021

Novel quinolone derivatives targeting human dihydroorotate dehydrogenase suppress Ebola virus infection in vitro

Mingli Gong, Yiqing Yang, Yi Ping Huang, Tianyu Gan, Yue Wu, Hongying Gao, Qianqian Li, Jianhui Nie, Weijin Huang, Youchun Wang, Rong Zhang, Jin Zhong, Fēi Dèng, Yu Rao, Qiang Ding

Antiviral Research

DOI

2021

Compartmentalization-aided interaction screening reveals extensive high-order complexes within the SARS-CoV-2 proteome

Weifan Xu, Gaofeng Pei, Hongrui Liu, Xiaohui Ju, Jing Wang, Qiang Ding, Pilong Li

Cell Reports

DOI

2021

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species

Ruoke Wang, Qi Zhang, Jiwan Ge, Wenlin Ren, Rui Zhang, Jun Lan, Bin Ju, Bin Su, Fengting Yu, Peng Chen, Huiyu Liao, Yingmei Feng, Xuemei Li, Xuanling Shi, Zheng Zhang, Fujie Zhang, Qiang Ding, Tong Zhang, Xinquan Wang, Linqi Zhang

Immunity

DOI

2021

Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry

Wenlin Ren, Yunkai Zhu, Yuyan Wang, Hongyang Shi, Yu Yin, Gaowei Hu, Fei Feng, Xiaomin Zhao, Jun Lan, Jianping Wu, Devin Kenney, Florian Douam, Yimin Tong, Jin Zhong, Youhua Xie, Xinquan Wang, Zhenghong Yuan, Dongming Zhou, Rong Zhang, Qiang Ding

PLoS Pathogens

DOI

2021

A novel cell culture system modeling the SARS-CoV-2 life cycle

Xiaohui Ju, Yunkai Zhu, Yuyan Wang, Jingrui Li, Jiaxing Zhang, Mingli Gong, Wenlin Ren, Sai Li, Jin Zhong, Linqi Zhang, Qiangfeng Cliff Zhang, Rong Zhang, Qiang Ding

PLoS Pathogens

DOI

2021

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2

Yinghui Liu, Gaowei Hu, Yuyan Wang, Wenlin Ren, Xiaomin Zhao, Fansen Ji, Yunkai Zhu, Fei Feng, Mingli Gong, Xiaohui Ju, Yuanfei Zhu, Xia Cai, Jun Lan, Jianying Guo, Min Xie, Lin Dong, Zihui Zhu, Jie Na, Jianping Wu, Xun Lan, Youhua Xie, Xinquan Wang, Zhenghong Yuan, Rong Zhang, Qiang Ding

Proceedings of the National Academy of Sciences

DOI

2021

A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry

Yunkai Zhu, Fei Feng, Gaowei Hu, Yuyan Wang, Yu Yin, Yuanfei Zhu, Wei Xü, Xia Cai, Zhiping Sun, Wendong Han, Rong Ye, Di Qu, Qiang Ding, Xinxin Huang, Hongjun Chen, Wei Xü, Youhua Xie, Qiliang Cai, Zhenghong Yuan, Rong Zhang

Nature Communications

DOI

2021

In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs

Lei Sun, Pan Li, Xiaohui Ju, Jian Yu Rao, Wenze Huang, Lili Ren, Shaojun Zhang, Tuanlin Xiong, Kui Xu, Xiaolin Zhou, Mingli Gong, Eric Alexander Miska, Qiang Ding, Jianwei Wang, Qiangfeng Cliff Zhang

Cell

DOI

2021

SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production

Lingling Luo, Zhean Li, Tiejun Zhao, Xiaohui Ju, Peixiang Ma, Bo-Xing Jin, Yulin Zhou, Su He, Jinhua Huang, Xun Xu, Yan Zou, Ping Li, Aibin Liang, Jia Liu, Tian H. Chi, Xingxu Huang, Qiang Ding, Zhigang Jin, Cheng Huang, Yu Zhang

《中国科学通报：英文版》

DOI

2021

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

Jiwan Ge, Ruoke Wang, Bin Ju, Qi Zhang, Jing Sun, Peng Chen, Senyan Zhang, Yuling Tian, Sisi Shan, Lin Cheng, Bing Zhou, Shuo Song, Juanjuan Zhao, Haiyan Wang, Xuanling Shi, Qiang Ding, Lei Liu, Jincun Zhao, Zheng Zhang, Xinquan Wang, Linqi Zhang

Nature Communications

DOI

2021

TRIM26 is a critical host factor for HCV replication and contributes to host tropism

Yisha Liang, Guigen Zhang, Qiheng Li, Lin Han, Xiaoyou Hu, Yu Guo, Wanyin Tao, Xiaomin Zhao, Mingzhe Guo, Tianyu Gan, Yimin Tong, Yongfen Xu, Zhuo Long Zhou, Qiang Ding, Wensheng Wei, Jin Zhong

Science Advances

DOI

2020

A Rare Novel CLCN2 Variation and Risk of Gilles de la Tourette Syndrome: Whole-Exome Sequencing in a Multiplex Family and a Follow-Up Study in a Chinese Population

Aihua Yuan, Zengge Wang, Wen Xu, Qiang Ding, Ying Zhao, Jingjing Han, Jinhua Sun

Frontiers In Psychiatry，Vol. 11

DOI

2020

Emotional Contexts Modulate Anticipatory Late Positive Component and Reward Feedback Negativity in Adolescents With Major Depressive Disorder

Wenhai Zhang, Caizhi Liao, Fanggui Tang, Shirui Liu, Jing Chen, Lulu Zheng, Ping Zhang, Qiang Ding, Hong Li

Frontiers In Psychiatry，Vol. 11

DOI

2020

前列腺穿刺结果的多参数预测列线图模型建立：上海单中心1585例经会阴前列腺穿刺回顾

胡梦博，杨天，吴亦硕，张立旻，姜昊文，丁强

《复旦学报(医学版)》

2020

A safety consideration of mesenchymal stem cell therapy on COVID-19

Yajun Cao, Hongyan Wu, Wanli Zhai, Ying Wang, Mengdi Li, Meng Li, Liu Yang, Ye Tian, Yunhao Song, Jun Li, Yinyin Wang, Qiang Ding, Linqi Zhang, Ming Cai, Zhijie Chang

Stem Cell Research

DOI

2020

Identification of functional cis-acting RNA elements in the hepatitis E virus genome required for viral replication

Xiaohui Ju, Guangtao Xiang, Mingli Gong, Rui Yang, Jierui Qin, Yafei Li, Yuchen Nan, Yonglin Yang, Qiangfeng Cliff Zhang, Qiang Ding

PLoS Pathogens

DOI

2019

中国男性运动员人群中慢性前列腺炎的现况调查

柳滟波，刘龙，丁岗，赵彦豪，沈逸凡，方祖军，丁强，熊祖泉

《中国临床医学》

2019

Hepatitis E Virus Assembly and Release

Xiaohui Ju, Qiang Ding

Viruses

DOI

2018

高功率双波长龙激光汽化术治疗良性前列腺增生症

吴忠，高鹏，王路加，茅善华，张元芳，丁强，沈周俊

《中国激光医学杂志》

2018

输尿管软镜治疗肾下盏结石合并感染的病例体会

高鹏，吴忠，王路加，茅善华，丁强

《中国激光医学杂志》

2018

新型双波长龙激光整块剜除术治疗浅表性膀胱癌:技巧及初步经验

吴忠，高鹏，茅善华，王路加，张元芳，丁强，沈周俊

《中国激光医学杂志》

2018

输尿管软镜钬激光碎石术治疗肾脏结石的策略选择

吴忠，高鹏，王路加，茅善华，冯陈陈，沈周俊，丁强

《中国激光医学杂志》

2016

输尿管软镜钬激光粉末化碎石技术治疗肾脏结石(附468例报告)

吴忠，高鹏，茅善华，冯陈陈，王路加，张元芳，沈周俊，丁强

《中国激光医学杂志》

2016

肾实质肿瘤术后腰部切口长期不适的手术相关因素分析

熊祖泉，于洋，冯陈陈，丁强，方祖军，郑捷

《中国临床医学》

2015

老年性下尿路功能障碍防治现状

丁强，邹鲁佳

《老年医学与保健》

2015

利用两种不同上皮细胞体外构建组织工程尿道的比较研究

谢雪锋，侯剑刚，陈刚，丁强

《复旦学报(医学版)》

2014

代谢综合征(MS)与前列腺癌:分子机制及治疗方法研究进展

胡梦博，姜昊文，丁强

《复旦学报(医学版)》

2014

经尿道电切术治疗成人输尿管囊肿的有效性和安全性

侯剑刚，王翔，方祖军，丁强

《复旦学报(医学版)》

2014

负载辐射凋亡MB49肿瘤细胞抗原的树突状细胞(DC)疫苗对小鼠膀胱癌的抑制作用

谢雪锋，侯剑刚，陈刚，丁强

《复旦学报(医学版)》

2014

钬激光碎石术联合新型结石捕获器(Ntrap)治疗输尿管上段结石

吴忠，高鹏，冯陈陈，王路加，张元芳，丁强

《中国激光医学杂志》

2014

标准输尿管软镜钬激光碎石术治疗肾脏结石

吴忠，高鹏，冯陈陈，王路加，张元芳，丁强

《中国激光医学杂志》

2012

肾上腺髓性脂肪瘤的诊断与治疗

瞿连喜，黎力平，王翔，丁强

《复旦学报(医学版)》

2011

前列腺癌伴骨转移患者的初始前列腺特异性抗原水平与癌症特异生存的相关性

张立旻，姜昊文，刘俊，那溶，丁强

《上海医学》

2011

双向凝胶电泳进行肾癌与健康人血清中差异表达蛋白的筛选和鉴定

石农，徐罡，袁海川，温晖，顾斌，刘俊，马志承，张立旻，项翠琴，陆晔，丁强，张元芳

《上海医学》

2010

iTRAQ技术在前列腺癌蛋白质组学研究中的应用

孙传玉，夏国伟，徐可，丁强

《中华男科学杂志》

2010

输尿管肾镜钬激光内切开术治疗输尿管狭窄和输尿管肾盂连接部狭窄

吴忠，丁强，姜昊文，高鹏，温晖，顾斌，张元芳

《中国激光医学杂志》

2010

半硬性输尿管肾镜钬激光碎石术治疗输尿管结石——附1625例报告

吴忠，丁强，姜昊文，高鹏，温晖，顾斌，张元芳

《中国激光医学杂志》

2010

输尿管肾镜联合结石捕获器在输尿管上段结石碎石中的应用

吴忠，丁强，姜昊文，高鹏，顾斌，温晖，张元芳

《中国激光医学杂志》

2010

负载表柔比星的磁性CS-PAA-EPI纳米粒在人膀胱癌移植瘤模型中的抗肿瘤作用

于江，熊晖，金讯波，郭佳，徐可，丁强

《复旦学报(医学版)》

2010

神经酰胺的凋亡效应在恶性肿瘤治疗中的作用

孙传玉，徐可，夏国伟，丁强

《复旦学报(医学版)》

2009

PMEPA1在前列腺癌中的表达及临床意义

杜俊华，姜昊文，关明，童仕俊，龚健，丁强

《复旦学报(医学版)》

2009

经尿道切除术后并发尿道狭窄的原因及技术改良

陆勇，丁强，徐可，王翔

《复旦学报(医学版)》

2009

重组PEDF腺病毒载体的构建及其抗膀胱癌效应的研究

蒋华，陈建红，王卫东，杭霞，张荣良，姜昊文，丁强

《检验医学》

2008

HIF-1α和HIF-2α在人肾透明细胞癌中的表达及意义

徐可，丁强，李映川，陈波，于江，方祖军，张元芳

《复旦学报(医学版)》

2008

腹膜后纤维化诊治上尿路梗阻11例报告

徐煜，徐可，姜昊文，陈忠清，丁强

《复旦学报(医学版)》

2008

IL-12双亚基共表达载体的构建及其在人骨髓间充质干细胞中的表达

高鹏，丁强，方祖军，郑捷

《中国医药生物技术》

2008

压力性尿失禁与尿道周围肌细胞凋亡的关系

郑捷，方祖军，丁强

《上海交通大学学报(医学版)》

2007

膀胱原发性淋巴瘤五例临床分析

王海燕，高鹏，谢毅，丁强

《中华内科杂志》

2007

应用尿动力学检查预测前列腺增生症术后疗效的研究

史东民，史沛清，刘国斌，孙长华，于雷，黄永刚，丁强

《黑龙江医学》

2007

雄激素受体信号通路改变导致前列腺癌非激素依赖性转化

蒋华，丁强

《中国煤炭工业医学杂志》

2007

载表柔比星磁性壳聚糖纳米粒的制备与表征检测

于江，徐可，丁强，李映川，郭佳，张元芳

《复旦学报(医学版)》

2007

螺旋CT平扫结合输尿管镜诊断和治疗输尿管阴性结石

姜昊文，吴忠，丁强，张元芳

《复旦学报(医学版)》

2006

经阴道无张力吊带术治疗女性压力性尿失禁的体会

方祖军，郑捷，徐可，丁强

《中华泌尿外科杂志》

2006

膀胱内灌注透明质酸治疗顽固性非细菌性膀胱炎的多中心观察

徐罡，丁强，孙颖浩，许传亮，黄翼然，薛蔚，夏术阶，凡杰，张元芳

《中华泌尿外科杂志》

2006

肾脏偶发性小占位病变的诊治分析

李映川，丁强，刘军

《复旦学报(医学版)》

2006

经腹膜外腹腔镜下前列腺癌根治术及其控尿技术

夏国伟，丁强，徐可，张元芳

《中华泌尿外科杂志》

2006

大鼠精原细胞的分离纯化及免疫化学研究

马良宏，丁强，王翔，汪洋，张元芳

《中华医学杂志》

2006

酒石酸托特罗定缓释片治疗膀胱过度活动症的多中心双盲双模拟随机对照临床研究

吴士良，崔一民，肖云翔，段继宏，王晓峰，丁强，张炜，那彦群

《中国临床药理学杂志》

2006

经闭孔无张力尿道中段悬吊术治疗女性压力性尿失禁

史东民，史沛清，孙长华，黄永刚，丁强，刘国斌，于雷，郑建华，于景江，唐秀泉，冯铁夫，李学东，姜维广

《中华泌尿外科杂志》

2006

阴茎阴囊Paget病130例分析

王忠，应俊，任晓敏，姚海军，杨堂斗，卢慕峻，丁强，张元芳

《中华泌尿外科杂志》

2006

输尿管子宫内膜异位症12例报告

高鹏，丁强，凡杰，夏术阶，方祖军，郑捷，张元芳

《中华泌尿外科杂志》

2006

叶绿素光敏剂-光动力学诱导PC3细胞凋亡的形态学研究

姜昊文，关明，龚健，丁强，张元芳

《中华泌尿外科杂志》

2006

女性压力性尿失禁经阴道无张力吊带术并发症处理

郑捷，方祖军，徐可，丁强

《复旦学报(医学版)》

2006

经腹膜外腹腔镜前列腺癌根治术(附10例报告)

于江，夏国伟，丁强，徐可，张元芳

《复旦学报(医学版)》

2006

原发性输尿管癌的临床诊断(附38例分析)

侯剑刚，王翔，丁强

《复旦学报(医学版)》

2006

早泄的流行病学研究

温晖，丁强，张元芳

《国际泌尿系统杂志》

2006

监测前列腺特异抗原对前列腺癌的临床价值

史东民，史沛清，孙长华，丁强，刘国斌，于雷，黄永刚

《黑龙江医学》

2005

叶绿素-光动力学诱导p53在PC3细胞和移植瘤的表达变化

姜昊文，张元芳，关明，丁强，陈宇明，龚健

《上海医学》

2005

翁沥通治疗慢性前列腺炎:多中心随机双盲安慰剂对照试验

徐罡，丁强，高小峰，孙颖浩，许明，张永康，王元天，黄翼然，鲁军，夏术阶，乔勇，徐月敏，张元芳

《中华泌尿外科杂志》

2005

前列腺癌患者联合雄激素阻断治疗中的肝功能异常与处理

姜昊文，张元芳，丁强，姚孟树，吴忠，方祖军，王继功，孙剑良，瞿连喜

《中华泌尿外科杂志》

2005

输尿管肾镜钬激光碎石术治疗输尿管结石

吴忠，丁强，姜昊文，周守静，郑景存，杨醌，赵鸿，张元芳

《中华泌尿外科杂志》

2005

经阴道无张力尿道中段悬吊术治疗女性压力性尿失禁

史沛清，史东民，刘国斌，李洪松，卢德祥，孙长华，丁强，于雷，刘福军，黄永刚

《中华泌尿外科杂志》

2005

伐地那非治疗勃起功能障碍的多中心、随机、双盲、对照研究

金杰，贺占举，张凯，朱积川，姜辉，潘天明，庄申镕，洪铠，唐文豪，马洪铭，王晓雄，何学酉，宋涛，黄翼然，周立新，戴继灿，丁强，方杰，徐罡，蔡松良，陈军，金晓东，郭应禄

《中华泌尿外科杂志》

2005

精原干细胞移植及其相关研究进展

马良宏，丁强，王翔

《中华医学杂志》

2005

国产新型光敏剂CDHS801光动力学杀伤膀胱癌机理的实验研究

郑景存，赵鸿，陈波，吴忠，姜昊文，丁强，张元芳

《中华医学杂志》

2004

18F-FDG PET在肾上腺病变定性诊断中的应用

张佐良，丁强，左传涛，管一晖，李强，杨鲲，张元芳

《中华泌尿外科杂志》

2004

成体干细胞分化调控研究的新进展

丁强，贾心善

《日本医学介绍》

2004

PET在泌尿生殖系统肿瘤诊断中的应用

姜昊文，管一晖，张元芳，丁强

《中华泌尿外科杂志》

2004

肾脏偶发癌临床分析(附116例报告)

燕翔，丁强，方祖军，郑捷，姚孟树，张元芳

《中华泌尿外科杂志》

2004

膀胱肿瘤手术前后血清和尿液bFGF浓度监测的临床意义

汪伟，丁强，张元芳，姜昊文，王翔，龚健

《中华泌尿外科杂志》

2004

单次腔内灌注表阿霉素预防浅表性膀胱癌术后复发的长期随访研究

刘本春，张元芳，王忠，丁强，陈波，于江，张鹏

《中华泌尿外科杂志》

2004

高能聚焦超声热疗治疗泌尿系统晚期恶性肿瘤

刘本春，沈天骊，王勇，丁强，王怡，张元芳

《上海医学》

2004

血清和尿液的碱性成纤维细胞生长因子诊断膀胱肿瘤的临床意义

姜昊文，张元芳，丁强，汪伟，龚健

《上海医学》

2004

重组转化生长因子α-绿脓杆菌外毒素融合蛋白对人膀胱癌细胞生长的抑制作用

燕翔，丁强，张元芳，徐永华

《中华外科杂志》

2004

浅表性膀胱癌PD-ECGF mRNA表达的意义

李纲，张元芳，丁强，严春寅，温端改

《中华外科杂志》

2003

无功能性肾上腺恶性肿瘤(附12例报告)

李强，张佐良，瞿连喜，吴忠，丁强，张元芳

《中华泌尿外科杂志》

2003

老年膀胱嗜铬细胞瘤一例报告

姜昊文，张元芳，丁强，王继功

《中华泌尿外科杂志》

2003

干扰素γ增加去氧氟尿苷和5-氟尿嘧啶抗膀胱癌作用的实验研究

李纲，张元芳，丁强，温端改，严春寅，瞿连喜，金建军

《中华泌尿外科杂志》

2003

α受体激动剂盐酸米多君治疗女性压力性尿失禁的临床研究

那彦群，吴士良，杨勇，段继宏，张小东，张晓鹏，王晓峰，丁强，徐可，方祖军，郑捷

《中华泌尿外科杂志》

2003

膀胱移行细胞癌中肿瘤细胞和间质细胞PD-ECGF的表达

李纲，张元芳，丁强，严春寅，温端改，郭震华

《苏州大学学报(医学版)》

2003

5α-还原酶在良性增生前列腺组织中的表达及意义

叶烈夫，张元芳，方祖军，丁强，姚孟树

《中华医学杂志》

2003

血管内皮生长因子在肾细胞癌的表达及临床意义

王金根，张元芳，丁强，陈波，金建军，王忠

《中华医学杂志》

2003

阴茎折断伴尿道损伤的诊断与治疗

应向荣，丁强，徐国强

《中华急诊医学杂志》

2002

肾上腺节细胞性神经瘤伴血儿茶酚胺异常一例

赵鸿，杨鲲，吴忠，丁强，张元芳

《中华外科杂志》

2002

前列腺肉瘤的诊治(附四例报告)

刘本春，王忠，丁强，张元芳，陈波

《中华泌尿外科杂志》

2002

新型5α-还原酶抑制剂爱普列特治疗良性前列腺增生的Ⅳ期临床研究

李宁忱，那彦群，丁强，张元芳，吴宏飞，杨宇如，鲁功成，郭应禄

《中华泌尿外科杂志》

2002

单次腔内灌注表柔比星预防浅表性膀胱癌术后复发

刘本春，张元芳，王忠，丁强，陈波，王继功，姜昊文

《中华外科杂志》

2002

米托蒽醌灌注预防膀胱癌术后复发的疗效观察(附98例报告)

瞿连喜，金建军，王继功，方祖军，丁强，张元芳

《中华泌尿外科杂志》

2002

成人双侧肾母细胞瘤一例报告

陈波，王忠，刘本春，高恩江，丁强，张元芳

《中华泌尿外科杂志》

2001

肾癌IGF-ⅠmRNA表达及与浸润转移的关系

孔宪国，张元芳，丁强，王忠，刘本春

《同济大学学报(医学版)》

2001

阴茎折断的诊断和治疗

王忠，刘本春，梁健峰，袁荫田，张元芳，丁强，姚孟树

《中华外科杂志》

2001

分子生物学技术在膀胱癌诊断中的研究现状与存在的问题

张元芳，王晓，丁强

《中华医学杂志》

2001

前列腺癌组织中Ⅰ型与Ⅱ型5α-还原酶表达的意义

叶烈夫，张元芳，方祖军，丁强，姚孟树

《中华医学杂志》

2001

新型抗胆碱能药物托特罗定治疗膀胱过度活动症的临床研究

吴士良，杨勇，薛兆英，那彦群，宋波，金锡御，丁强，张元芳，郭应禄

《中华泌尿外科杂志》

2001

前列腺组织中Ⅰ、Ⅱ型5α-还原酶表达的研究

张元芳，叶烈夫，丁强，方祖军，姚孟树，施达仁

《中华泌尿外科杂志》

2000

膀胱移行细胞癌伴前列腺癌的诊断与治疗

瞿连喜，金建军，方祖军，姚孟树，丁强，张元芳

《中华泌尿外科杂志》

2000

糖尿病性阴茎勃起功能障碍大鼠阴茎海绵体一氧化氮合酶活性的测定

王为服，张元芳，丁强，徐一甄，董德欣

《中华泌尿外科杂志》

2000

吡喃阿霉素膀胱内灌注预防浅表性膀胱癌术后复发

王翔，张元芳，瞿连喜，丁强，王忠

《中华泌尿外科杂志》

2000

爱普列特治疗良性前列腺增生Ⅱ期临床研究

薛兆英，韩文科，金杰，张元芳，丁强，王晓雄，曹立军

《中国临床药理学杂志》

2000

新型5α-还原酶抑制剂-爱普列特治疗良性前列腺增生症Ⅱ期临床试验研究

张元芳，丁强，冯善章，蔡松良，王翔

《中国临床药理学杂志》

2000

经尿道铲状电极汽化切除浅表性膀胱肿瘤

瞿连喜，丁强，姜昊文，方祖军，姚孟树，王忠，张元芳

《中华外科杂志》

2000

不同前列腺组织中睾酮及双氢睾酮含量测定的研究

张元芳，叶烈夫，丁强，方组军，姚孟树，施达仁

《中华外科杂志》

2000

前列腺癌患者伴其他器官的原发性恶性肿瘤

方祖军，丁强，姚孟树，张元芳

《中华外科杂志》

1999

B超发现的未能扪及的睾丸肿块

叶烈夫，王翔，张元芳，丁强，王勇

《中华外科杂志》

1999

前列腺组织端粒酶活性检测对前列腺癌的诊断价值

王翔，张元芳，丁强，叶烈夫，瞿连喜，贾万健

《中华外科杂志》

1999

前列腺癌130例诊断分析

王忠，张元芳，丁强，刘本春，姜昊文

《上海医学》

1999

外伤性后尿道断裂26例的治疗

崔云阁，刘国滨，刘福军，刘欣，丁强

《黑龙江医学》

1999

PICP和ICTP诊断前列腺癌骨转移的价值

姜昊文，张元芳，丁强，王忠，瞿连喜，邓守真

《中华泌尿外科杂志》

1999

糖尿病性阴茎勃起功能障碍大鼠模型海绵体超微结构的研究

王为服，张元芳，丁强，徐一甄，凌治萍

《中华泌尿外科杂志》

1998

端粒酶活性与膀胱癌预后的初步研究

彭钧铮，张元芳，丁强，潘崇贤

《中华外科杂志》

1998

微血管密度在判断肾细胞癌转移中的作用

王忠，张元芳，刘本春，丁强，孔宪国

《中华泌尿外科杂志》

1998

肾细胞癌骨转移的诊治(附四例报告)

刘本春，张元芳，王忠，丁强

《中华泌尿外科杂志》

1998

血管内皮细胞生长因子mRNA在肾细胞癌中的表达

王忠，张元芳，孔宪国，丁强

《中华泌尿外科杂志》

1998

膀胱癌细胞株和组织端粒酶活性研究

彭钧铮，张元芳，丁强，赵琳琳，潘崇贤

《中华泌尿外科杂志》

1998

99mTc-EC肾动态显像在肾移植中的应用

彭钧铮，张元芳，陈可靖，孙晓光，张立，丁强，王国民，张永康

《中华核医学与分子影像杂志》

1997

膀胱癌组织中端粒酶活性研究

彭钧铮，张元芳，丁强，潘崇贤

《中华泌尿外科杂志》

1997

睾丸癌组织中 K-ras 基因点突变和 ras 基因产物 P21 表达的评价

丁强，张元芳，孙逊，邹宇

《中华泌尿外科杂志》

1997

原癌基因c-myc在前列腺癌组织中的扩增和表达分析

张元芳，丁强，孙逊，邹宇

《中华泌尿外科杂志》

1996

肾癌组织中C－erbB－2基因的扩增和P185蛋白的表达分析

丁强，张炯，孙逊，潘文生

《中华泌尿外科杂志》

1996

聚合酶链反应和核酸杂交在检测阴茎癌人乳头状瘤病毒中的作用

丁强，张元芳，孙逊

《中华外科杂志》

精选作品

期刊论文

腋窝入路单孔腔镜电剪刀法乳房皮下腺体切除技术要点

血管内介入栓塞治疗腹部手术后胃肠瘘并发出血

SARS‐CoV‐2 enhances lysosomal exocytosis and deacidifies lysosomes to facilitate viral release

Real-time tracking of dual-labeled fluorescent SARS-CoV-2 reveals that the nucleocapsid mutations R203K/G204R accelerate viral uncoating

EIF4H and YBX1 are essential host factors for hepatitis E virus replication and pathogenesis

Vesicle-associated membrane protein 5 is an intrinsic defense factor for embryonic stem cells against coronaviruses

Interferon-stimulated gene GALNT2 restricts respiratory virus infections

The prion-like characteristic of ORF3 contributes to virion release and pathogenesis of hepatitis E virus

The R203M and D377Y mutations of the nucleocapsid protein promote SARS-CoV-2 infectivity by impairing RIG-I-mediated antiviral signaling

UHRF1 restricts HCoV-229E infection through epigenetic silencing of the viral receptor APN

DAZAP2 functions as a pan-coronavirus restriction factor by inhibiting viral entry and genomic replication

Glycosylphosphatidylinositol biosynthesis functions as a conserved host defense pathway against coronaviruses via regulation of LY6E

Structural basis of DNA replication fidelity of the Mpox virus

Enantiomer-dependent and modification-free DNA matrix as an adjuvant for subunit vaccines against SARS-CoV-2 or pneumococcal infections

Design, synthesis and biological evaluation of dapsone derivatives with broad-spectrum antiviral activity

TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry

Zika virus NS5 protein inhibits type I interferon signaling via CRL3 E3 ubiquitin ligase-mediated degradation of STAT2

Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection

Viral N protein hijacks deaminase-containing RNA granules to enhance SARS-CoV-2 mutagenesis

Chemical Recording of Pump‐Specific Drug Efflux in Living Cells

Receptor binding mechanism and immune evasion capacity of SARS-CoV-2 BQ.1.1 lineage

Drupacine as a potent SARS-CoV-2 replication inhibitor in vitro

Structural insights into the Langya virus attachment glycoprotein

Natural evidence of coronaviral 2′-O-methyltransferase activity affecting viral pathogenesis via improved substrate RNA binding

Establishment of replication-competent vesicular stomatitis virus recapitulating SADS-CoV entry

A Comparative Study of Human Pluripotent Stem Cell-Derived Macrophages in Modeling Viral Infections

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

Recapitulation of the Powassan virus life cycle in cell culture

Modeling antiviral response in the liver using human pluripotent stem cell-derived macrophages

Evolution of SARS-CoV-2 Spikes shapes their binding affinities to animal ACE2 orthologs

Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling

The PRMT5/WDR77 complex restricts hepatitis E virus replication

A tissue specific-infection mouse model of SARS-CoV-2

Evolution of Immune Evasion and Host Range Expansion by the SARS-CoV-2 B.1.1.529 (Omicron) Variant

SARS‐CoV‐2 NSP8 suppresses type I and III IFN responses by modulating the RIG‐I/MDA5, TRIF, and STING signaling pathways

Vitamin C promotes ACE2 degradation and protects against SARS‐CoV‐2 infection

Design and characterization of novel SARS-CoV-2 fusion inhibitors with N-terminally extended HR2 peptides

A vaccine delivery system promotes strong immune responses against SARS‐CoV‐2 variants

A preliminary study of comprehensive behavioral intervention for tics in Chinese children with chronic tic disorder or Tourette syndrome

Characterization and analysis of linear epitopes corresponding to SARS‐CoV‐2 outbreak in Jilin Province, China

A CRISPR activation screen identifies genes that enhance SARS-CoV-2 infection

Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2

SARS-CoV-2 Omicron Variants Reduce Antibody Neutralization and Acquire Usage of Mouse ACE2

The Deubiquitinase USP29 Promotes SARS-CoV-2 Virulence by Preventing Proteasome Degradation of ORF9b

Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication

Characterization of SARS-CoV-2 Variants B.1.617.1 (Kappa), B.1.617.2 (Delta), and B.1.618 by Cell Entry and Immune Evasion

An ultrapotent RBD-targeted biparatopic nanobody neutralizes broad SARS-CoV-2 variants

Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.

输尿管软镜钬激光碎石技术治疗CT值≥1200 HU肾结石的碎石方式选择

输尿管软镜联合钬激光技术治疗肾盏憩室内结石

上海市泌尿外科会诊咨询服务部成立35周年纪念

Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption

Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2

Molecular determinants for regulation of G3BP1/2 phase separation by the SARS-CoV-2 nucleocapsid protein

Genome-wide transcriptomic analysis of highly virulent African swine fever virus infection reveals complex and unique virus host interaction

Novel quinolone derivatives targeting human dihydroorotate dehydrogenase suppress Ebola virus infection in vitro

Compartmentalization-aided interaction screening reveals extensive high-order complexes within the SARS-CoV-2 proteome

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species

Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry

A novel cell culture system modeling the SARS-CoV-2 life cycle

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2

A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry

In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs

SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

TRIM26 is a critical host factor for HCV replication and contributes to host tropism

A Rare Novel CLCN2 Variation and Risk of Gilles de la Tourette Syndrome: Whole-Exome Sequencing in a Multiplex Family and a Follow-Up Study in a Chinese Population

Emotional Contexts Modulate Anticipatory Late Positive Component and Reward Feedback Negativity in Adolescents With Major Depressive Disorder

前列腺穿刺结果的多参数预测列线图模型建立：上海单中心1585例经会阴前列腺穿刺回顾

A safety consideration of mesenchymal stem cell therapy on COVID-19

Identification of functional cis-acting RNA elements in the hepatitis E virus genome required for viral replication

中国男性运动员人群中慢性前列腺炎的现况调查

Hepatitis E Virus Assembly and Release

高功率双波长龙激光汽化术治疗良性前列腺增生症

输尿管软镜治疗肾下盏结石合并感染的病例体会

新型双波长龙激光整块剜除术治疗浅表性膀胱癌:技巧及初步经验

输尿管软镜钬激光碎石术治疗肾脏结石的策略选择