胡国斌｜中国海洋大学｜学者主页

2026

Genome-wide Identification and Expression Profiling Reveal the Galectin Gene Family Diversity and their Possible Role in Antibacterial Mucosal Immunity in Japanese Flounder (Paralichthys olivaceus)

Weiheng Sun, Guobin Hu, Songlin Chen, Quanchao Chen, Yuanxin Yang

Marine Biotechnology

DOI

2026

Insights into the role of TLR21 in innate immunity of Japanese flounder (Paralichthys olivaceus)

Yuting Song, Yuanxin Yang, Shuo Zhang, Songlin Chen, Guobin Hu

Fish & Shellfish Immunology

DOI

2026

Time-Series Transcriptomics of a Gill Cell Line (BTG) from Chinese Bahaba (Bahaba taipingensis) During ISKNV Infection (3–24 hpi)

Chenfei Guo, Zhihong Gong, Fei Fang, Xihong Li, Lei Wang, Na Wang, Zhangfan Chen, Yan Lin, Kuoqiu Yan, Guobin Hu, Songlin Chen

Fishes

DOI

2026

De novo establishment of a stable brain cell line from Cephalopholis sonnerati (tomato grouper) and transcriptomic dissection of its response to nervous necrosis virus (NNV) infection

Zhihong Gong, Fei Fang, Xiaoli Guo, Chenfei Guo, Na Wang, Lei Wang, Chongwei Wang, Guobin Hu, Bo Zhou, Songlin Chen

Fish & Shellfish Immunology

DOI

2026

Grass carp (Ctenopharyngodon idella) SIRT7 negatively regulates HIF-1 signaling pathway by interacting with HIF-1α independent of deacetylase activity under hypoxia

Shuo Zhang, Yuanxin Yang, Yuting Song, Songlin Chen, Guobin Hu

Aquaculture

DOI

2025

Characterization of TLR14 ligands, adaptor proteins and immune mechanisms in Japanese flounder (Paralichthys olivaceus)

Yuting Song, Zhihong Gong, Songlin Chen, Guobin Hu

Fish & Shellfish Immunology

DOI

2025

Establishment and characterization of a gill cell line from turbot (Scophthalmus maximus)

Jiaqi Wang, Xiang Shi, Zhihong Gong, Songlin Chen, Guobin Hu

Fish & Shellfish Immunology

DOI

2024

Multi-organ transcriptomic profiles and gene-regulation network underlying vibriosis resistance in tongue sole

Quanchao Chen, Xinran Ma, Jie Wang, Meng Shi, Guobin Hu, Songlin Chen, Qian Zhou

Scientific Data

DOI

2024

Establishment and characterization of cell line from fin of Chinense bahaba (Bahaba taipingensis) and transcriptome analysis of its response to megalocytivirus SKIV-SD strain infection

Zhihong Gong, Qi Zhang, Na Wang, Lei Wang, Zhangfan Chen, Lin Yan, Kuoqiu Yan, Guobin Hu, Songlin Chen

Aquaculture

DOI

2023

Establishment and identification of a skin cell line from Chinese tongue sole (Cynoglossus semilaevis) and analysis of the changes in its transcriptome upon LPS stimulation

Zhihong Gong, Chenfei Guo, Jiacheng Wang, Songlin Chen, Guobin Hu

Fish & Shellfish Immunology

DOI

2023

Bmp4 in Zebrafish Enhances Antiviral Innate Immunity through p38 MAPK (Mitogen-Activated Protein Kinases) Pathway

Lihui Chen, Shenjie Zhong, Yajun Wang, Xinyuan Wang, Zhenhui Liu, Guobin Hu

International Journal of Molecular Sciences

DOI

2023

Transcriptome analysis reveals immune-related genes in tissues of Vibrio anguillarum-infected turbot Scophthalmus maximus

Yuting Song, Maqsood Ahmed Soomro, Xianzhi Dong, Guobin Hu

Journal of Oceanology and Limnology

DOI

2023

Establishment, characterization and application in germplasm conservation and disease resistance: An embryonic cell line from Yangtze sturgeon (Acipenser dabryanus)

Zhihong Gong, Qi Zhang, Juanjuan Liu, Guobin Hu, Songlin Chen, Na Wang

Aquaculture

DOI

2022

齐口裂腹鱼鳃丝细胞系的建立、鉴定及免疫研究

巩志宏，王娜，刘娟娟，胡国斌，陈松林

《中国水产科学》

2022

大菱鲆TLR14基因的克隆和相关功能研究

孙莹，李松，胡国斌

《中国海洋大学学报(自然科学版)》

2022

Identification and functional analysis of histone 1.2-like in red sea bream (Pagrus major)

Lianfei Song, Maqsood Ahmed Soomro, Lingshu Wang, Yuting Song, Guobin Hu

Developmental & Comparative Immunology

DOI

2022

Transcriptome analysis of turbot (Scophthalmus maximus) head kidney and liver reveals immune mechanism in response to Vibrio anguillarum infection

Yuting Song, Xianzhi Dong, Guobin Hu

Journal of Fish Diseases

DOI

2021

牙鲆NTF3基因克隆与表达分析

陈志鹏，朱颖，王磊，胡国斌，陈松林

《农业生物技术学报》

2021

Toll样受体9(TLR9)在鱼类中的研究进展

王冠杰，胡国斌

《畜牧兽医科技信息》

2021

Molecular cloning, identification and expression analysis of MDA5/MAVS/TRAF3/TANK/TBK1, five pivotal molecules of RLR signalling pathway in turbot ( Scophthalmus maximus )

Maqsood Ahmed Soomro, Li Song, Tushar Ramesh Pavase, Qiuming Liu, Guobin Hu

Aquaculture Research

DOI

2021

Transcriptome analysis of red sea bream (Pagrus major) head kidney and spleen infected by Vibrio anguillarum

Lianfei Song, Xianzhi Dong, Guobin Hu

Aquaculture Reports

DOI

2021

Transcriptome analysis reveals immune‐related differentially expressed genes in the hepatopancreas and gills of Penaeus vannamei after Vibrio anguillarum infection

Yuting Song, Lianfei Song, Maqsood Ahmed Soomro, Xianzhi Dong, Guobin Hu

Aquaculture Research

DOI

2020

Transcriptome analysis of Giant grouper ( Epinephelus lanceolatus ) kidney and spleen in response to spotted knifejaw iridovirus (SKIV) infection

Gui‐liang Zheng, Qian Zhou, Kun‐ming Li, Wenteng Xu, Lei Wang, Guobin Hu, Song‐lin Chen

Aquaculture Research

DOI

2020

Molecular Characterization and Expression Analysis of Toll-like Receptor 9 Gene in Turbot, Scophthalmus Maximus

Guanjie Wang, Xuepeng Li, Qiuming Liu, Xianzhi Dong, Guobin Hu

Journal of Clinical Medicine Research

DOI

2020

Adaptor Molecule TRIF in Teleost

Guanjie Wang, Guobin Hu

Journal of Clinical Medicine Research

DOI

2018

Molecular cloning and expression study on Toll-like receptor 5M in turbot, Scophthalmus maximus

Dahai Liu, Jinjing Chen, Song Li, Guobin Hu

Developmental & Comparative Immunology

DOI

2017

Cloning and expression study of an IRF4a gene and its two transcript variants in turbot, Scophthalmus maximus

Song Li, Guobin Hu, Zhipeng Chen, Lianfei Song, Guanjie Wang, Dahai Liu, Qiuming Liu

Fish & Shellfish Immunology

DOI

2017

Cloning and expression analysis of a Toll-like receptor 21 ( TLR21 ) gene from turbot, Scophthalmus maximus

Song Li, Guanjie Wang, Dahai Liu, Qiuming Liu, Guobin Hu

Developmental & Comparative Immunology

DOI

2016

Cloning and expression study of a Toll-like receptor 2 (tlr2) gene from turbot, Scophthalmus maximus

Haiyan Zhang, Guobin Hu, Qiuming Liu, Shicui Zhang

Fish & Shellfish Immunology

DOI

2016

Interferon regulatory factor 4b (IRF4b) in Japanese flounder, Paralichthys olivaceus: Sequencing, ubiquitous tissue distribution and inducible expression by poly(I:C) and DNA virus

Dahai Liu, Jinjing Chen, Haiyan Zhang, Mengzhu Hu, Huimin Lou, Qiuming Liu, Shicui Zhang, Guobin Hu

Developmental & Comparative Immunology

DOI

2015

Molecular cloning and expression analysis of interferon stimulated gene 15 (ISG15) in turbot, Scophthalmus maximus

Jing-Yun Lin, Guobin Hu, Dahai Liu, Song Li, Qiu-Ming Liu, Shicui Zhang

Fish & Shellfish Immunology

DOI

2015

Molecular cloning and expression studies of the adapter molecule myeloid differentiation factor 88 (MyD88) in turbot (Scophthalmus maximus)

Jing-Yun Lin, Guobin Hu, Changhong Yu, Song Li, Qiu-Ming Liu, Shicui Zhang

Developmental & Comparative Immunology

DOI

2015

Cloning and expression analysis of a Toll-like receptor 22 (tlr22) gene from turbot, Scophthalmus maximus

Guobin Hu, Shoufeng Zhang, Xi Yang, Dahai Liu, Qiu-Ming Liu, Shicui Zhang

Fish & Shellfish Immunology

DOI

2014

Molecular cloning and characterization of interferon regulatory factor 9 (IRF9) in Japanese flounder, Paralichthys olivaceus

Guobin Hu, Ming-Yu Zhao, Jing-Yun Lin, Qiu-Ming Liu, Shicui Zhang

Fish & Shellfish Immunology

DOI

2013

Structural and expression studies of interferon regulatory factor 8 in Japanese flounder, Paralichthys olivaceus

Guobin Hu, Xiaoling Chen, Qiaoli Gong, Qiuming Liu, Shicui Zhang, Xianzhi Dong

Fish & Shellfish Immunology

DOI

2013

Anti-viral activity of galectin-1 from flounder Paralichthys olivaceus

Shousheng Liu, Guobin Hu, Chen Sun, Shicui Zhang

Fish & Shellfish Immunology

DOI

2013

Antiviral activity of phosvitin from zebrafish Danio rerio

Chen Sun, Lili Hu, Shousheng Liu, Guobin Hu, Shicui Zhang

Developmental & Comparative Immunology

DOI

2012

Molecular cloning and expression analysis of interferon regulatory factor 8 (IRF8) in turbot, Scophthalmus maximus

Xiaoling Chen, Guobin Hu, Xianzhi Dong, Qiuming Liu, Shicui Zhang

Veterinary Immunology and Immunopathology

DOI

2012

Characteristics of the interferon regulatory factor 5 (IRF5) and its expression in response to LCDV and poly I:C challenges in Japanese flounder, Paralichthys olivaceus

Guobin Hu, Huimin Lou, Xianzhi Dong, Qiu-Ming Liu, Shicui Zhang

Developmental & Comparative Immunology

DOI

2011

Molecular characterization and expression analysis of interferon regulatory factor 5 (IRF-5) in turbot, Scophthalmus maximus

Jun Xia, Guobin Hu, Xianzhi Dong, Qiu-Ming Liu, Shicui Zhang

Fish & Shellfish Immunology

DOI

2011

An IRF-3 homolog that is up-regulated by DNA virus and poly I:C in turbot, Scophthalmus maximus

Guobin Hu, Jun Xia, Huimin Lou, Xiaoling Chen, Jing Li, Qiu-Ming Liu

Fish & Shellfish Immunology

DOI

2010

Cloning and expression analysis of interferon regulatory factor 7 (IRF-7) in turbot, Scophthalmus maximus

Guobin Hu, Jun Xia, Huimin Lou, Qiuming Liu, Jing-Yun Lin, Xiangyan Yin, Xianzhi Dong

Developmental & Comparative Immunology

DOI

2010

Interferon regulatory factor 3 (IRF-3) in Japanese flounder, Paralichthys olivaceus: Sequencing, limited tissue distribution, inducible expression and induction of fish type I interferon promoter

Guobin Hu, Xiangyan Yin, Huimin Lou, Jun Xia, Xianzhi Dong, Jianyie Zhang, Qiuming Liu

Developmental & Comparative Immunology

DOI

2010

Retroviral Delivery of Simian Virus 40 Large T Antigen Gene into Primary Cultured Ovary Cells of the Penaeid Shrimp,Penaeus chinensis: Indirect Evidence of Retroviral Integration

Guobin Hu, Dan Wang, Jixiang Chen

Journal of the World Aquaculture Society

DOI

2008

A novel immortalization vector for the establishment of penaeid shrimp cell lines

Guobin Hu, Dan Wang, Changhong Wang, Kunfeng Yang

In Vitro Cellular & Developmental Biology - Animal

DOI

2007

Expression and characterization of a metalloprotease from aVibrio parahaemolyticusisolate

Xiaoyan Luan, Jixiang Chen, Xiao‐Hua Zhang, Yun Li, Guobin Hu

Canadian Journal of Microbiology

DOI

2005

几种免疫促进剂对中国对虾血细胞数量、形态结构以及酚氧化酶产量和活性的影响

汪小锋，樊廷俊，丛日山，胡国斌

《水产学报》

2005

Effects of several immunostimulants on the number, ultrastructure of hemocytes and the yield,activities of phenoloxidase in Penaeus chinensis

Wang Xiaofeng, Fan Tingjun, Rishan Cong, Guobin Hu

JOURNAL OF FISHERIES OF CHINA

1999

紫外辐射诱导草鱼肾脏细胞系(CIK)的程序性死亡

屈三甫，郑从义，胡国斌，彭芳，栾亚华，丁桂珍，刘颖

《水产学杂志》

精选作品

期刊论文

Genome-wide Identification and Expression Profiling Reveal the Galectin Gene Family Diversity and their Possible Role in Antibacterial Mucosal Immunity in Japanese Flounder (Paralichthys olivaceus)

Insights into the role of TLR21 in innate immunity of Japanese flounder (Paralichthys olivaceus)

Time-Series Transcriptomics of a Gill Cell Line (BTG) from Chinese Bahaba (Bahaba taipingensis) During ISKNV Infection (3–24 hpi)

De novo establishment of a stable brain cell line from Cephalopholis sonnerati (tomato grouper) and transcriptomic dissection of its response to nervous necrosis virus (NNV) infection

Grass carp (Ctenopharyngodon idella) SIRT7 negatively regulates HIF-1 signaling pathway by interacting with HIF-1α independent of deacetylase activity under hypoxia

Characterization of TLR14 ligands, adaptor proteins and immune mechanisms in Japanese flounder (Paralichthys olivaceus)

Establishment and characterization of a gill cell line from turbot (Scophthalmus maximus)

Multi-organ transcriptomic profiles and gene-regulation network underlying vibriosis resistance in tongue sole

Establishment and characterization of cell line from fin of Chinense bahaba (Bahaba taipingensis) and transcriptome analysis of its response to megalocytivirus SKIV-SD strain infection

Establishment and identification of a skin cell line from Chinese tongue sole (Cynoglossus semilaevis) and analysis of the changes in its transcriptome upon LPS stimulation

Bmp4 in Zebrafish Enhances Antiviral Innate Immunity through p38 MAPK (Mitogen-Activated Protein Kinases) Pathway

Transcriptome analysis reveals immune-related genes in tissues of Vibrio anguillarum-infected turbot Scophthalmus maximus

Establishment, characterization and application in germplasm conservation and disease resistance: An embryonic cell line from Yangtze sturgeon (Acipenser dabryanus)

齐口裂腹鱼鳃丝细胞系的建立、鉴定及免疫研究

大菱鲆TLR14基因的克隆和相关功能研究

Identification and functional analysis of histone 1.2-like in red sea bream (Pagrus major)

Transcriptome analysis of turbot (Scophthalmus maximus) head kidney and liver reveals immune mechanism in response to Vibrio anguillarum infection

牙鲆NTF3基因克隆与表达分析

Toll样受体9(TLR9)在鱼类中的研究进展

Molecular cloning, identification and expression analysis of MDA5/MAVS/TRAF3/TANK/TBK1, five pivotal molecules of RLR signalling pathway in turbot ( Scophthalmus maximus )

Transcriptome analysis of red sea bream (Pagrus major) head kidney and spleen infected by Vibrio anguillarum

Transcriptome analysis reveals immune‐related differentially expressed genes in the hepatopancreas and gills of Penaeus vannamei after Vibrio anguillarum infection

Transcriptome analysis of Giant grouper ( Epinephelus lanceolatus ) kidney and spleen in response to spotted knifejaw iridovirus (SKIV) infection

Molecular Characterization and Expression Analysis of Toll-like Receptor 9 Gene in Turbot, Scophthalmus Maximus

Adaptor Molecule TRIF in Teleost

Molecular cloning and expression study on Toll-like receptor 5M in turbot, Scophthalmus maximus

Cloning and expression study of an IRF4a gene and its two transcript variants in turbot, Scophthalmus maximus

Cloning and expression analysis of a Toll-like receptor 21 ( TLR21 ) gene from turbot, Scophthalmus maximus

Cloning and expression study of a Toll-like receptor 2 (tlr2) gene from turbot, Scophthalmus maximus

Interferon regulatory factor 4b (IRF4b) in Japanese flounder, Paralichthys olivaceus: Sequencing, ubiquitous tissue distribution and inducible expression by poly(I:C) and DNA virus

Molecular cloning and expression analysis of interferon stimulated gene 15 (ISG15) in turbot, Scophthalmus maximus

Molecular cloning and expression studies of the adapter molecule myeloid differentiation factor 88 (MyD88) in turbot (Scophthalmus maximus)

Cloning and expression analysis of a Toll-like receptor 22 (tlr22) gene from turbot, Scophthalmus maximus

Molecular cloning and characterization of interferon regulatory factor 9 (IRF9) in Japanese flounder, Paralichthys olivaceus

Structural and expression studies of interferon regulatory factor 8 in Japanese flounder, Paralichthys olivaceus

Anti-viral activity of galectin-1 from flounder Paralichthys olivaceus

Antiviral activity of phosvitin from zebrafish Danio rerio

Molecular cloning and expression analysis of interferon regulatory factor 8 (IRF8) in turbot, Scophthalmus maximus

Characteristics of the interferon regulatory factor 5 (IRF5) and its expression in response to LCDV and poly I:C challenges in Japanese flounder, Paralichthys olivaceus

Molecular characterization and expression analysis of interferon regulatory factor 5 (IRF-5) in turbot, Scophthalmus maximus

An IRF-3 homolog that is up-regulated by DNA virus and poly I:C in turbot, Scophthalmus maximus

Cloning and expression analysis of interferon regulatory factor 7 (IRF-7) in turbot, Scophthalmus maximus

Interferon regulatory factor 3 (IRF-3) in Japanese flounder, Paralichthys olivaceus: Sequencing, limited tissue distribution, inducible expression and induction of fish type I interferon promoter

Retroviral Delivery of Simian Virus 40 Large T Antigen Gene into Primary Cultured Ovary Cells of the Penaeid Shrimp,Penaeus chinensis: Indirect Evidence of Retroviral Integration

A novel immortalization vector for the establishment of penaeid shrimp cell lines

Expression and characterization of a metalloprotease from aVibrio parahaemolyticusisolate

几种免疫促进剂对中国对虾血细胞数量、形态结构以及酚氧化酶产量和活性的影响

Effects of several immunostimulants on the number, ultrastructure of hemocytes and the yield,activities of phenoloxidase in Penaeus chinensis

紫外辐射诱导草鱼肾脏细胞系(CIK)的程序性死亡

研究方向