百晓学者学者目录

陈亮

副研究员、研究员，复旦大学

精选作品

期刊论文

2026

视网膜光损伤及欧洲越橘花色苷护眼作用机制研究进展

沈佳辰，陈亮，许肇初，段彦旭，李双石，张洁如，彭效明

《食品科技》

DOI

2026

基于系统认知的免疫学教学思考与探索

曾跃勤，陈菲，李奕霏，齐芮，周磊，陈亮

《继续医学教育》

2025

The CHPT-pSTAT3-SLC7A11 signaling axis controls progression and ferroptosis susceptibility of pancreatic cancer

Jianhui Yang, Jiang Liu, Zeyin Rong, Zhen Tan, Wei Wang, Qingcai Meng, Miaoyan Wei, Jie Hua, Bo Zhang, Xianjun Yu, Jin Xu, Chen Liang

Translational Oncology

DOI

2025

Global burden of early-onset pancreatic cancer attributable to metabolic risks from 1990 to 2021, and projections to 2030

Yingjin Fang, Yile Xu, Faliang Xing, Weixin Zhang, Chen Liang, Qingcai Meng, Jialin Li, Jin Xu, Wei Wang, Yi Qin, Xianjun Yu, Bo Zhang

Frontiers in Oncology

DOI

2025

Correction to: Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways

Yang Li, Zhichao Xi, Xiaoqiong Chen, Shuangfan Cai, Chen Liang, Zhen Wang, Ying-Yi Li, Hongsheng Tan, Yuanzhi Lao, Hong‐Xi Xu

Cell Death and Disease

DOI

2025

Dense stroma activates the TGF-β1/FBW7 axis to induce metabolic subtype switching in pancreatic cancer

Zeyin Rong, Jianhui Yang, Jiang Liu, Qingcai Meng, Jie Hua, Zhen Tan, Bo Zhang, Yuan Liu, Qiong Du, Wei Wang, Xianjun Yu, Jin Xu, Chen Liang

International Journal of Surgery

DOI

2024

将更多免疫学领域科技成果转化为守护人民健康的产品

陈亮，谢欣希

《羊城晚报》

2024

Topical application of Glauber’s salt accelerates the absorption of abdominal fluid after pancreatectomy

Jialin Li, Jie Hua, Haiyan Ruan, Hang Xu, Chen Liang, Qingcai Meng, Jiang Liu, Bo Zhang, Jin Xu, Si Shi, Xianjun Yu, Wei Wang

BMC Surgery

DOI

2024

CircRREB1 Mediates Metabolic Reprogramming and Stemness Maintenance to Facilitate Pancreatic Ductal Adenocarcinoma Progression

Zeyin Rong, Jin Xu, Yang Jianhui, Wei Wang, Rong Tang, Zi-Feng Zhang, Zhen Tan, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Chen Liang, Xianjun Yu, Si Shi

Cancer Research

DOI

2024

Intratumoral CD38+CD19+B cells associate with poor clinical outcomes and immunosuppression in patients with pancreatic ductal adenocarcinoma

Heng Zhu, Jin Xu, Wei Wang, Bo Zhang, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Xianjun Yu, Si Shi

EBioMedicine

DOI

2024

Integration of single-nucleus and exosome RNA sequencing dissected inter-cellular communication and biomarkers in pancreatic ductal adenocarcinoma

Rong Tang, Zi-Feng Zhang, Jin Xu, Wei J. Wang, Qingcai Meng, Yuan Liu, Qiong Du, Chen Liang, Jie Hua, Bo Zhang, Xianjun Yu, Si Shi

Computational and Structural Biotechnology Journal

DOI

2024

CPT1B maintains redox homeostasis and inhibits ferroptosis to induce gemcitabine resistance via the KEAP1/NRF2 axis in pancreatic cancer

Abudureyimu Tuerhong, Jin Xu, Wei Wang, Si Shi, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Xianjun Yu, Chen Liang

Surgery

DOI

2023

Modulating miRNA binding sites within circRNA for enhanced translation efficiency

Kewei Zhang, Shan Ge, Liang Chen

JUSTC

DOI

2023

Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response

Rong Tang, Jin Xu, Wei Wang, Qingcai Meng, Chenghao Shao, Yiyin Zhang, Yubin Lei, Zi-Feng Zhang, Yuan Liu, Qiong Du, Xiangjie Sun, Di Wu, Chen Liang, Jie Hua, Bo Zhang, Xianjun Yu, Si Shi

Cell Reports Medicine

DOI

2023

Radical antegrade modular pancreatosplenectomy (RAMPS) versus standard retrograde pancreatosplenectomy (SRPS) for resectable body and tail pancreatic adenocarcinoma: protocol of a multicenter, prospective, randomized phase III control trial (CSPAC-3)

Jialin Li, Si Shi, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Hang Xu, Miaoyan Wei, Bo Zhang, Jin Xu, Wei Wang, Xianjun Yu

Trials

DOI

2023

CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma

Xiaomeng Liu, Rong Tang, Jin Xu, Zhen Tan, Chen Liang, Qingcai Meng, Yubin Lei, Jie Hua, Yiyin Zhang, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi

Gut

DOI

2023

Integrated analysis revealed hypoxia signatures and LDHA related to tumor cell dedifferentiation and unfavorable prognosis in pancreatic adenocarcinoma

Mingwei Dong, Rong Tang, Wei Wang, Jin Xu, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Xianjun Yu, Bo Zhang, Si Shi

Translational Oncology

DOI

2023

Cuproptosis-Related Gene DLAT as a Novel Biomarker Correlated with Prognosis, Chemoresistance, and Immune Infiltration in Pancreatic Adenocarcinoma: A Preliminary Study Based on Bioinformatics Analysis

Zengli Fang, Wei Wang, Yuan Liu, Jie Hua, Chen Liang, Liu Jiang, Bo Zhang, Si Shi, Xianjun Yu, Qingcai Meng, Jin Xu

Current Oncology

DOI

2023

Mechanical Regulation of Redox Balance via the Induction of the PIN1/NRF2/ARE Axis in Pancreatic Cancer

Chen Liang, Zeyin Rong, Abudureyimu Tuerhong, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi, Jin Xu

International Journal of Molecular Sciences

DOI

2023

Mitochondria-Related Transcriptome Characterization Associated with the Immune Microenvironment, Therapeutic Response and Survival Prediction in Pancreatic Cancer

Jia Dong, Jiang Liu, Bo Zhang, Chen Liang, Jie Hua, Qingcai Meng, Miaoyan Wei, Wei Wang, Xianjun Yu, Jin Xu

International Journal of Molecular Sciences

DOI

2022

Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs

Liang Chen, Yucong Wang, Jia-Mei Lin, Zhenxing Song, Qin-Wei Wang, Wenfang Zhao, Yan Wang, Xiao-Yu Xiu, Yu-Qiong Deng, Xiu Li, Qiqi Li, Xiaolin Wang, Jing-Xin Li, Xu Liu, Kun-Peng Liu, Jincong Zhou, Kuan Li, Yu-Chan Liu, S. Liao, Qin Deng, Chao Xu, Qianwen Sun, Shengzhou or sheng-zhou wu, Kai-Ming Zhang, Min-Xin Guan, Tianhua Zhou, Fei Sun, Xiujun Cai, Chuan Huang, G. Shan

Nature Communications

DOI

2022

Signaling pathways in cancer‐associated fibroblasts: recent advances and future perspectives

Zengli Fang, Qingcai Meng, Jin Xu, Wei Wang, Bo Zhang, Jiang Liu, Chen Liang, Jie Hua, Yingjun Zhao, Xianjun Yu, Si Shi

《癌症：英文版》

DOI

2022

RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m6A-YTHDF2-dependent manner

Zhen Tan, Si Shi, Jin Xu, Xiaomeng Liu, Yubin Lei, Bo Zhang, Jie Hua, Qingcai Meng, Wei Wang, Xianjun Yu, Chen Liang

Oncogene

DOI

2021

CircRNA in cancer: Fundamental mechanism and clinical potential.

Liang Chen, Shan Ge

Cancer Letters

DOI

2021

Circular RNAs in physiology and non-immunological diseases.

Liang Chen, Chuan Huang, Shan Ge

TIBS -Trends in Biochemical Sciences. Regular ed

DOI

2021

Exosomes derived from immunogenically dying tumor cells as a versatile tool for vaccination against pancreatic cancer

Wenxi Zhou, Xinli Chen, Yu Zhou, Si Shi, Chen Liang, Xianjun Yu, Hongyi Chen, Qin Guo, Yiwen Zhang, Peixin Liu, Chao Li, Yongchao Chu, Yifan Luo, Yu Wang, Zheng Zhou, Zhenhao Zhao, Qinjun Chen, Tao Sun, Chen Jiang

Biomaterials

DOI

2021

Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives

Xiaoqi Mao, Jin Xu, Wei Wang, Chen Liang, Jie Hua, Jiang Liu, Bo Zhang, Qingcai Meng, Xianjun Yu, Si Shi

Molecular Cancer

DOI

2021

Ferroptosis: At the Crossroad of Gemcitabine Resistance and Tumorigenesis in Pancreatic Cancer

Jianhui Yang, Jin Xu, Bo Zhang, Zhen Tan, Qingcai Meng, Jie Hua, Jiang Liu, Wei Wang, Si Shi, Xianjun Yu, Chen Liang

International Journal of Molecular Sciences

DOI

2021

Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis

Zeyin Rong, Si Shi, Zhen Tan, Jin Xu, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Chen Liang

Molecular Cancer

DOI

2021

Analysis of Immune-Related Signatures Related to CD4+ T Cell Infiltration With Gene Co-Expression Network in Pancreatic Adenocarcinoma

Zhen Tan, Yubin Lei, Bo Zhang, Si Shi, Jiang Liu, Xianjun Yu, Jin Xu, Chen Liang

Frontiers in Oncology

DOI

2021

Overcoming chemoresistance by targeting reprogrammed metabolism: the Achilles' heel of pancreatic ductal adenocarcinoma

Abudureyimu Tuerhong, Jin Xu, Si Shi, Zhen Tan, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Chen Liang

Cellular and Molecular Life Sciences

DOI

2021

Head-to-head comparison between FOLFIRINOX and gemcitabine plus nab-paclitaxel in the neoadjuvant chemotherapy of localized pancreatic cancer: a systematic review and meta-analysis

Rong Tang, Qingcai Meng, Wei Wang, Chen Liang, Jie Hua, Jin Xu, Xianjun Yu, Si Shi

Gland Surgery

DOI

2021

From the Immune Profile to the Immunoscore: Signatures for Improving Postsurgical Prognostic Prediction of Pancreatic Neuroendocrine Tumors

Miaoyan Wei, Jin Xu, Jie Hua, Qingcai Meng, Chen Liang, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi

Frontiers in Immunology

DOI

2021

Identification of the Roles of a Stemness Index Based on mRNA Expression in the Prognosis and Metabolic Reprograming of Pancreatic Ductal Adenocarcinoma

Rong Tang, Xiaomeng Liu, Wei Wang, Jie Hua, Jin Xu, Chen Liang, Qingcai Meng, Jiang Liu, Bo Zhang, Xianjun Yu, Si Shi

Frontiers in Oncology

DOI

2021

Role of tumor mutation burden-related signatures in the prognosis and immune microenvironment of pancreatic ductal adenocarcinoma

Rong Tang, Xiaomeng Liu, Wei Wang, Jie Hua, Jin Xu, Chen Liang, Qingcai Meng, Jiang Liu, Bo Zhang, Xianjun Yu, Si Shi

Cancer Cell International

DOI

2021

Deciphering the Prognostic Implications of the Components and Signatures in the Immune Microenvironment of Pancreatic Ductal Adenocarcinoma

Rong Tang, Xiaomeng Liu, Chen Liang, Jie Hua, Jin Xu, Wei Wang, Qingcai Meng, Jiang Liu, Bo Zhang, Xianjun Yu, Si Shi

Frontiers in Immunology

DOI

2021

Hyperdense Pancreatic Ductal Adenocarcinoma: Clinical Characteristics and Proteomic Landscape

Xu He, Jie Hua, Qingcai Meng, Xiaohong Wang, Jin Xu, Wei Wang, Bo Zhang, Jiang Liu, Chen Liang, Xianjun Yu, Si Shi

Frontiers in Oncology

DOI

2021

Microorganisms in chemotherapy for pancreatic cancer: An overview of current research and future directions

Siyuan Lu, Jie Hua, Jin Xu, Miaoyan Wei, Chen Liang, Qingcai Meng, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Si Shi

International Journal of Biological Sciences

DOI

2021

Construction of a novel risk model based on the random forest algorithm to distinguish pancreatic cancers with different prognoses and immune microenvironment features

Yalan Lei, Rong Tang, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Jie Hua, Xianjun Yu, Wei Wang, Si Shi

Bioengineered

DOI

2020

Circular RNAs from BOULE play conserved roles in protection against stress-induced fertility decline

Liuze Gao, Shuhui Chang, Wenjuan Xia, Xiaolin Wang, Chen-Wang Zhang, Liping Cheng, Xu Liu, Liang Chen, Qing-Hua Shi, Juan Huang, E. Xu, Shan Ge

Science Advances

DOI

2020

lncRNA PART1 and MIR17HG as ΔNp63α direct targets regulate tumor progression of cervical squamous cell carcinoma

Hanyuan Liu, Chen-Chen Zhu, Zhihao Xu, Juan Wang, Lili Qian, Qingqing Zhou, Zhen Shen, Wei-Dong Zhao, Weihua Xiao, Liang Chen, Ying Zhou

Cancer Science

DOI

2020

Prognostic value of circulating tumor DNA in pancreatic cancer: a systematic review and meta-analysis

Zengli Fang, Qingcai Meng, Bo Zhang, Si Shi, Jiang Liu, Chen Liang, Jie Hua, Xianjun Yu, Jin Xu, Wei Ting Wang

Aging

DOI

2020

The value of a metabolic reprogramming-related gene signature for pancreatic adenocarcinoma prognosis prediction

Zhen Tan, Yubin Lei, Jin Xu, Si Shi, Jie Hua, Bo Zhang, Qingcai Meng, Jiang Liu, Yiyin Zhang, Miaoyan Wei, Xianjun Yu, Chen Liang

Aging

DOI

2020

The promising role of noncoding RNAs in cancer-associated fibroblasts: an overview of current status and future perspectives

Zengli Fang, Jin Xu, Bo Zhang, Wei Wang, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Xianjun Yu, Si Shi

Journal of Hematology & Oncology

DOI

2020

The role of ferroptosis regulators in the prognosis, immune activity and gemcitabine resistance of pancreatic cancer

Rong Tang, Jie Hua, Jin Xu, Chen Liang, Qingcai Meng, Jiang Liu, Bo Zhang, Xianjun Yu, Si Shi

Annals of Translational Medicine

DOI

2020

The role of m6A-related genes in the prognosis and immune microenvironment of pancreatic adenocarcinoma

Rong Tang, Yiyin Zhang, Chen Liang, Jin Xu, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Xianjun Yu, Si Shi

PeerJ

DOI

2020

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

Rong Tang, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Xianjun Yu, Si Shi

Journal of Hematology & Oncology

DOI

2020

Hypoxia: a barricade to conquer the pancreatic cancer

Zhen Tan, Jin Xu, Bo Zhang, Si Shi, Xianjun Yu, Chen Liang

Cellular and Molecular Life Sciences

DOI

2020

A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance

Qingcai Meng, Chen Liang, Jie Hua, Bo Zhang, Jiang Liu, Yiyin Zhang, Miaoyan Wei, Xianjun Yu, Jin Xu, Si Shi

Theranostics

DOI

2019

ΔNp63α exerts antitumor functions in cervical squamous cell carcinoma

Ying Zhou, Hanyuan Liu, Juan Wang, Xiaolin Wang, Lili Qian, Fei Xu, Weiguo Song, Da-Bao Wu, Zhen Shen, D. Feng, B. Ling, Weihua Xiao, Shan Ge, Liang Chen

Oncogene

DOI

2019

Analyses of a Panel of Transcripts Identified From a Small Sample Size and Construction of RNA Networks in Hepatocellular Carcinoma

Zhiyong Sheng, Xiaolin Wang, Ge-Liang Xu, Shan Ge, Liang Chen

Frontiers in Genetics

DOI

2019

Effects of LncRNA Lnc-LIF-AS on cell proliferation, migration and invasion in a human cervical cancer cell line.

Weiguo Song, Juan Wang, Hanyuan Liu, Chenchen Zhu, Fei Xu, Lili Qian, Zhen Shen, Jing Zhu, Shuai Yin, J. Qin, Liang Chen, Da-Bao Wu, B. Nashan, Shan Ge, Weihua Xiao, Ying Zhou

Cytokine

DOI

2019

Role of Damage DNA-Binding Protein 1 in Pancreatic Cancer Progression and Chemoresistance

Yiyin Zhang, Yubin Lei, Jin Xu, Jie Hua, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Xianjun Yu, Si Shi

Cancers

DOI

2019

The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implications

Xiaomeng Liu, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Jie Hua, Xianjun Yu, Si Shi

Molecular Cancer

DOI

2019

The impact of the nodal status and resection margin on the effectiveness of adjuvant chemotherapy for pancreatic cancer: It calls for more careful evaluation

Zhen Tan, Chen Liang, Xianjun Yu, Si Shi

Journal of Surgical Oncology

DOI

2019

A PD-L2-based immune marker signature helps to predict survival in resected pancreatic ductal adenocarcinoma

Yiyin Zhang, Jin Xu, Jie Hua, Jiang Liu, Chen Liang, Qingcai Meng, Miaoyan Wei, Bo Zhang, Xianjun Yu, Si Shi

Journal for ImmunoTherapy of Cancer

DOI

2019

TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status

Chen Liang, Jin Xu, Qingcai Meng, Bo Zhang, Jiang Liu, Jie Hua, Yiyin Zhang, Si Shi, Xianjun Yu

Autophagy

DOI

2019

The microbiota and microbiome in pancreatic cancer: more influential than expected

Miao-Yan Wei, Si Shi, Chen Liang, Qing-Cai Meng, Jie Hua, Yi-Yin Zhang, Jiang Liu, Bo Zhang, Jin Xu, Xianjun Yu

Molecular Cancer

DOI

2019

Codelivery Nanosystem Targeting the Deep Microenvironment of Pancreatic Cancer

Xinli Chen, Wenxi Zhou, Chen Liang, Si Shi, Xianjun Yu, Qinjun Chen, Tao Sun, Yifei Lü, Yujie Zhang, Qin Guo, Chao Li, Yu Zhang, Chen Jiang

Nano Letters

DOI

2019

Sequential Targeting TGF‐β Signaling and KRAS Mutation Increases Therapeutic Efficacy in Pancreatic Cancer

Yuanyuan Pei, Chen Liang, Yukun Huang, Jiahao Wang, Jingxian Feng, Minjun Xu, Yu Chen, Qingxiang Song, Gan Jiang, Xiao Qin Gu, Qian Zhang, Xiaoling Gao, Jun Chen

Small

DOI

2019

Nab-paclitaxel plus gemcitabine as first-line treatment for advanced pancreatic cancer: a systematic review and meta-analysis

Yiyin Zhang, Jin Xu, Jie Hua, Jiang Liu, Chen Liang, Qingcai Meng, Quanxing Ni, Si Shi, Xianjun Yu

Journal of Cancer

DOI

2018

Comparing two approaches of miR-34a target identification, biotinylated-miRNA pulldown vs miRNA overexpression

H. M. Awan, Abdullah Shah, Farooq Rashid, Shuai Wei, Liang Chen, Shan Ge

RNA Biology

DOI

2018

Targetable long non-coding RNAs in cancer treatments.

Liang Chen, E. E. Dzakah, Shan Ge

Cancer Letters

DOI

2018

GPx1 is involved in the induction of protective autophagy in pancreatic cancer cells in response to glucose deprivation

Qingcai Meng, Jin Xu, Chen Liang, Jiang Liu, Jie Hua, Yiyin Zhang, Quanxing Ni, Si Shi, Xianjun Yu

Cell Death and Disease

DOI

2018

PIN1 Maintains Redox Balance via the c-Myc/NRF2 Axis to Counteract Kras-Induced Mitochondrial Respiratory Injury in Pancreatic Cancer Cells

Chen Liang, Si Shi, Mingyang Liu, Yi Qin, Qingcai Meng, Jie Hua, Shunrong Ji, Yu‐Qing Zhang, Jingxuan Yang, Jin Xu, Quanxing Ni, Min Li, Xianjun Yu

Cancer Research

DOI

2018

The Strain Ratio as Obtained by Endoscopic Ultrasonography Elastography Correlates With the Stroma Proportion and the Prognosis of Local Pancreatic Cancer

Si Shi, Chen Liang, Jin Xu, Qingcai Meng, Jie Hua, Xiujiang Yang, Quanxing Ni, Xianjun Yu

Annals of Surgery

DOI

2018

Current status and dilemma of second-line treatment in advanced pancreatic cancer: is there a silver lining?

Jie Hua, Si Shi, Dingkong Liang, Chen Liang, Qingcai Meng, Bo Zhang, Quanxing Ni, Jin Xu, Xianjun Yu

OncoTargets and Therapy

DOI

2018

Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling

Qingcai Meng, Si Shi, Chen Liang, Dingkong Liang, Jie Hua, Bo Zhang, Jin Xu, Xianjun Yu

Oncogene

DOI

2018

MiR‐29a, targeting caveolin 2 expression, is responsible for limitation of pancreatic cancer metastasis in patients with normal level of serum CA125

Chen Liang, Si Shi, Qingcai Meng, Dingkong Liang, Jie Hua, Yi Qin, Bo Zhang, Jin Xu, Quanxing Ni, Xianjun Yu

International Journal of Cancer

DOI

2018

Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways

Yang Li, Zhichao Xi, Xiaoqiong Chen, Shuangfan Cai, Chen Liang, Zhen Wang, Ying-Yi Li, Hongsheng Tan, Yuanzhi Lao, Hong‐Xi Xu

Cell Death and Disease

DOI

2018

TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer

Jinfeng Xiang, Qiangsheng Hu, Yi Qin, Shunrong Ji, Wenyan Xu, Wensheng Liu, Si Shi, Chen Liang, Jiang Liu, Qingcai Meng, Dingkong Liang, Quanxing Ni, Jin Xu, Bo Zhang, Xianjun Yu

Cell Death and Disease

DOI

2018

Mismatch repair status as a beneficial predictor of fluorouracil-based adjuvant chemotherapy for pancreatic cancer

Dingkong Liang, Si Shi, Chen Liang, Qingcai Meng, Bo Zhang, Quanxing Ni, Jin Xu, Xianjun Yu

Surgery

DOI

2018

Proposed Modification of the 8th Edition of the AJCC Staging System for Pancreatic Ductal Adenocarcinoma

Si Shi, Jie Hua, Chen Liang, Qingcai Meng, Dingkong Liang, Jin Xu, Quanxing Ni, Xianjun Yu

Annals of Surgery

DOI

2017

Erratum: BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin

Zhao-Yong Li, Chuan Huang, Chun Bao, Liang Chen, Mei Lin, Xiao-Lin Wang, Guo-Lin Zhong, Bin Yu, Wan-Chen Hu, Li-Min Dai, Peng-Fei Zhu, Zhao-Xia Chang, Qing-Fa Wu, Yi Zhao, Ya Jia, Ping Xu, Hui-Jie Liu, Shan Ge

Nature Structural &Molecular Biology

DOI

2017

Induction of miR-3648 Upon ER Stress and Its Regulatory Role in Cell Proliferation

Farooq Rashid, H. M. Awan, Abdullah Shah, Liang Chen, Shan Ge

International Journal of Molecular Sciences

DOI

2017

The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5

Abdullah Shah, Farooq Rashid, H. M. Awan, Shanshan Hu, Xiaolin Wang, Liang Chen, Shan Ge

Stem Cells International

DOI

2017

Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going

Chen Liang, Si Shi, Qingcai Meng, Dingkong Liang, Shunrong Ji, Bo Zhang, Yi Qin, Jin Xu, Quanxing Ni, Xianjun Yu

Experimental & Molecular Medicine

DOI

2017

Do anti-stroma therapies improve extrinsic resistance to increase the efficacy of gemcitabine in pancreatic cancer?

Chen Liang, Si Shi, Qingcai Meng, Dingkong Liang, Shunrong Ji, Bo Zhang, Yi Qin, Jin Xu, Quanxing Ni, Xianjun Yu

Cellular and Molecular Life Sciences

DOI

2017

Diagnostic and prognostic value of carcinoembryonic antigen in pancreatic cancer: a systematic review and meta-analysis

Qingcai Meng, Si Shi, Chen Liang, Dingkong Liang, Wenyan Xu, Shunrong Ji, Bo Zhang, Quanxing Ni, Jin Xu, Xianjun Yu

OncoTargets and Therapy

DOI

2017

Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma

Chen Liang, Yi Qin, Bo Zhang, Shunrong Ji, Si Shi, Wenyan Xu, Jiang Liu, Jinfeng Xiang, Dingkong Liang, Qiangsheng Hu, Quanxing Ni, Jin Xu, Xianjun Yu

Molecular Cancer Research

DOI

2017

Diagnostic Accuracy of a CA125-Based Biomarker Panel in Patients with Pancreatic Cancer: A Systematic Review and Meta-Analysis

Qingcai Meng, Si Shi, Chen Liang, Jinfeng Xiang, Dingkong Liang, Bo Zhang, Yi Qin, Shunrong Ji, Wenyan Xu, Jin Xu, Quanxing Ni, Xianjun Yu

Journal of Cancer

DOI

2016

ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer

Chen Liang, Yi Qin, Bo Zhang, Shunrong Ji, Si Shi, Wenyan Xu, Jiang Liu, Jinfeng Xiang, Dingkong Liang, Qiangsheng Hu, Quanxing Ni, Xianjun Yu, Jin Xu

Cancer Letters

DOI

2016

Energy sources identify metabolic phenotypes in pancreatic cancer

Chen Liang, Yi Qin, Bo Zhang, Shunrong Ji, Si Shi, Wenyan Xu, Jiang Liu, Jinfeng Xiang, Dingkong Liang, Qiangsheng Hu, Liang Liu, Chen Liu, Guopei Luo, Quanxing Ni, Jin Xu, Xianjun Yu

Acta Biochimica et Biophysica Sinica

DOI

2016

Metabolic plasticity in heterogeneous pancreatic ductal adenocarcinoma

Chen Liang, Yi Qin, Bo Zhang, Shunrong Ji, Si Shi, Wenyan Xu, Jiang Liu, Jinfeng Xiang, Dingkong Liang, Qiangsheng Hu, Quanxing Ni, Jin Xu, Xianjun Yu

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

DOI

2016

FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer

Shunrong Ji, Yi Qin, Chen Liang, Run Huang, Si Shi, Jiang Liu, Kaizhou Jin, Dingkong Liang, Wenyan Xu, Bo Zhang, Liang Liu, Chen Liu, Jin Xu, Quanxing Ni, Paul J. Chiao, Min Li, Xianjun Yu

Clinical Cancer Research

DOI

2016

ALDOA functions as an oncogene in the highly metastatic pancreatic cancer

Shunrong Ji, Bo Zhang, Jiang Liu, Yi Qin, Chen Liang, Si Shi, Kaizhou Jin, Dingkong Liang, Wenyan Xu, Huaxiang Xu, Wenquan Wang, Chuntao Wu, Liang Liu, Chen Liu, Jin Xu, Quanxing Ni, Xianjun Yu

Cancer Letters

DOI

2015

Altered expression of microRNAs in the response to ER stress

Li-Min Dai, Chuan-Xin Huang, Liang Chen, Shan Ge, Zhao-Yong Li

DOI

2015

The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation

Liang Chen, Farooq Rashid, Abdullah Shah, H. M. Awan, Mingming Wu, An-Dong Liu, Jun Wang, T. Zhu, Zhao-Feng Luo, Shan Ge

Proceedings of the National Academy of Sciences of the United States of America

DOI

2015

Circular RNAs in Eukaryotic Cells

Liang Chen, Chuan Huang, Xiaolin Wang, Shan Ge

Current Genomics

DOI

2015

Circular RNAs remain peculiarly unclear in biogenesis and function

Liang Chen, Shan Ge

Science China Life Sciences

DOI

2015

Exon-intron circular RNAs regulate transcription in the nucleus

Zhao-Yong Li, Chuan Huang, Chun Bao, Liang Chen, Mei Lin, Xiao-Lin Wang, Guo-Lin Zhong, Bin Yu, Wan-Chen Hu, Li-Min Dai, Peng-Fei Zhu, Zhao-Xia Chang, Qing-Fa Wu, Yi Zhao, Ya Jia, Ping Xu, Hui-Jie Liu, Shan Ge

Nature Structural &Molecular Biology

DOI

2015

FGF ‐1/‐3/ FGFR 4 signaling in cancer‐associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP ‐7

Yu‐Pan Bai, Kun Shang, Huan Chen, Fei Ding, Zhen Wang, Chen Liang, Ye Xu, Menghong Sun, Ying-Yi Li

Cancer Science

DOI

2015

miR-33a suppresses the nuclear translocation of β-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells

Chen Liang, Zhen Wang, Ying-Yi Li, Baohua Yu, Fei Zhang, Hongyu Li

Tumor Biology

DOI

2015

MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine

Chen Liang, Xianjun Yu, Xiaozhong Guo, Meng-Hong Sun, Zhen Wang, Yao Hua Song, Quan-Xing Ni, Hongyu Li, Naofumi Mukaida, Ying-Yi Li

Oncotarget

DOI

2015

Orthotopic inflammation-related pancreatic carcinogenesis in a wild-type mouse induced by combined application of caerulein and dimethylbenzanthracene

Chen Liang, Zhen Wang, Li Wu, Chen Wang, Baohua Yu, Xiuzhong Yao, Xiao-Lin Wang, Yingyi Li

Tumor Biology

DOI

2014

Use of regulators and inhibitors of Pim-1, a serine/threonine kinase, for tumour therapy (Review)

Chen Liang, Ying-Yi Li

Molecular Medicine Reports

DOI

2013

Environmental RNA interference in animals

Lingfeng Meng, Liang Chen, Zhaoyong Li, Zheng-Xing Wu, Shan Ge

DOI

2013

Roles of microRNAs in the Caenorhabditis elegans nervous system.

Lingfeng Meng, Liang Chen, Zhao-Yong Li, Zheng-Xing Wu, Shan Ge

Journal of genetics and genomics = Yi chuan xue bao

DOI

2012

Signals from noncoding RNAs: unconventional roles for conventional pol III transcripts.

Shanshan Hu, Jing Wu, Liang Chen, Shan Ge

International Journal of Biochemistry and Cell Biology

DOI

预印本

2024

Stromal Activation Induces the Switch of Metabolic Subtype in Pancreatic Cancer

Zeyin Rong, Jianhui Yang, Jiang Liu, Qingcai Meng, Jie Hua, Zhen Tan, Bo Zhang, Yuan Liu, Qiong Du, Wei Wang, Xianjun Yu, Jin Xu, Chen Liang

SSRN Electronic Journal

DOI

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